LOCUS       DAVDFK010000001       110362 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.01, whole genome shotgun sequence.
ACCESSION   DAVDFK010000001 DAVDFK010000000
VERSION     DAVDFK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 110362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 110362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..110362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.01"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(278..475)
                     /locus_tag="VUR04_000001"
     CDS             complement(278..475)
                     /locus_tag="VUR04_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5339984.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(460..738)
                     /locus_tag="VUR04_000002"
                     /pseudo
     CDS             complement(460..738)
                     /locus_tag="VUR04_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
     gene            complement(777..1562)
                     /locus_tag="VUR04_000003"
     CDS             complement(777..1562)
                     /locus_tag="VUR04_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5339985.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1564..2382)
                     /locus_tag="VUR04_000004"
     CDS             complement(1564..2382)
                     /locus_tag="VUR04_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET5339986.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2384..3376)
                     /locus_tag="VUR04_000005"
     CDS             complement(2384..3376)
                     /locus_tag="VUR04_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5339987.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(4421..4783)
                     /locus_tag="VUR04_000006"
     CDS             complement(4421..4783)
                     /locus_tag="VUR04_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET5339988.1"
                     /translation="MLEVGLNSLINLFTFTFDILYPIVKVGHADDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSTVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            complement(5625..6314)
                     /gene="rplA"
                     /locus_tag="VUR04_000007"
     CDS             complement(5625..6314)
                     /gene="rplA"
                     /locus_tag="VUR04_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET5339989.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(6522..6947)
                     /gene="rplK"
                     /locus_tag="VUR04_000008"
     CDS             complement(6522..6947)
                     /gene="rplK"
                     /locus_tag="VUR04_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET5339990.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(7256..7972)
                     /locus_tag="VUR04_000009"
     CDS             complement(7256..7972)
                     /locus_tag="VUR04_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET5339991.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKPKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVVNKGDYYSIQGKYDEIVIANKHYPLSKDYNPGENPTAKAELLKLI
                     AAMQAAGYPISDHYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASDLSLEEYYGFEGGDYVD"
     gene            complement(7990..8451)
                     /locus_tag="VUR04_000010"
     CDS             complement(7990..8451)
                     /locus_tag="VUR04_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET5339992.1"
                     /translation="MCLICQRIELIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMENPVKFRFLEEMSLVQETVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     TGDMKGHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKHLA"
     gene            complement(8453..9490)
                     /locus_tag="VUR04_000011"
     CDS             complement(8453..9490)
                     /locus_tag="VUR04_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET5339993.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEEHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEERIDLPMTTHFAFSVFEE
                     VGHGANSNIPKEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATELM
                     VDAYLKSEGVS"
     gene            complement(9588..10913)
                     /gene="brnQ"
                     /locus_tag="VUR04_000012"
     CDS             complement(9588..10913)
                     /gene="brnQ"
                     /locus_tag="VUR04_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET5339994.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(11084..11176)
                     /locus_tag="VUR04_000013"
     CDS             complement(11084..11176)
                     /locus_tag="VUR04_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5339995.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(11219..11371)
                     /locus_tag="VUR04_000014"
     CDS             complement(11219..11371)
                     /locus_tag="VUR04_000014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5339996.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGTHNLPLSQ
                     LADSYD"
     gene            complement(11531..12109)
                     /locus_tag="VUR04_000015"
     CDS             complement(11531..12109)
                     /locus_tag="VUR04_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET5339997.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMTKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(12163..13563)
                     /gene="pepV"
                     /locus_tag="VUR04_000016"
     CDS             complement(12163..13563)
                     /gene="pepV"
                     /locus_tag="VUR04_000016"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET5339998.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(13576..14181)
                     /locus_tag="VUR04_000017"
     CDS             complement(13576..14181)
                     /locus_tag="VUR04_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET5339999.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            14352..15152
                     /locus_tag="VUR04_000018"
     CDS             14352..15152
                     /locus_tag="VUR04_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340000.1"
                     /translation="MKKFSLLLAILPFLVACENQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(15334..16167)
                     /locus_tag="VUR04_000019"
     CDS             complement(15334..16167)
                     /locus_tag="VUR04_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET5340001.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(16157..18001)
                     /gene="uvrC"
                     /locus_tag="VUR04_000020"
     CDS             complement(16157..18001)
                     /gene="uvrC"
                     /locus_tag="VUR04_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET5340002.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(18041..18742)
                     /locus_tag="VUR04_000021"
     CDS             complement(18041..18742)
                     /locus_tag="VUR04_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET5340003.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(18821..20053)
                     /gene="murN"
                     /locus_tag="VUR04_000022"
     CDS             complement(18821..20053)
                     /gene="murN"
                     /locus_tag="VUR04_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET5340004.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNSIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDIFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(20058..21278)
                     /gene="murM"
                     /locus_tag="VUR04_000023"
     CDS             complement(20058..21278)
                     /gene="murM"
                     /locus_tag="VUR04_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET5340005.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELVNVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(21390..22169)
                     /locus_tag="VUR04_000024"
     CDS             complement(21390..22169)
                     /locus_tag="VUR04_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET5340006.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(22238..23899)
                     /locus_tag="VUR04_000025"
     CDS             complement(22238..23899)
                     /locus_tag="VUR04_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET5340007.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(24074..26296)
                     /gene="recJ"
                     /locus_tag="VUR04_000026"
     CDS             complement(24074..26296)
                     /gene="recJ"
                     /locus_tag="VUR04_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET5340008.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEEM
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            26573..27331
                     /locus_tag="VUR04_000027"
     CDS             26573..27331
                     /locus_tag="VUR04_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5340009.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            27371..28135
                     /locus_tag="VUR04_000028"
     CDS             27371..28135
                     /locus_tag="VUR04_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5340010.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNSKTIGVAQGSITQCLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            28148..28825
                     /locus_tag="VUR04_000029"
     CDS             28148..28825
                     /locus_tag="VUR04_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5340011.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            28835..29494
                     /locus_tag="VUR04_000030"
     CDS             28835..29494
                     /locus_tag="VUR04_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5340012.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVHNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYKAGMSQGFTSAQILYYIILPQASRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            29752..30942
                     /locus_tag="VUR04_000031"
     CDS             29752..30942
                     /locus_tag="VUR04_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET5340013.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(31263..32144)
                     /locus_tag="VUR04_000032"
     CDS             complement(31263..32144)
                     /locus_tag="VUR04_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET5340014.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(32285..33613)
                     /gene="vncS"
                     /locus_tag="VUR04_000033"
     CDS             complement(32285..33613)
                     /gene="vncS"
                     /locus_tag="VUR04_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET5340015.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVAQD"
     gene            complement(33610..34266)
                     /gene="vncR"
                     /locus_tag="VUR04_000034"
     CDS             complement(33610..34266)
                     /gene="vncR"
                     /locus_tag="VUR04_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET5340016.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(34315..34398)
                     /gene="pep27"
                     /locus_tag="VUR04_000035"
     CDS             complement(34315..34398)
                     /gene="pep27"
                     /locus_tag="VUR04_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET5340017.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(34578..35957)
                     /gene="vex3"
                     /locus_tag="VUR04_000036"
     CDS             complement(34578..35957)
                     /gene="vex3"
                     /locus_tag="VUR04_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET5340018.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(36009..36656)
                     /gene="vex2"
                     /locus_tag="VUR04_000037"
     CDS             complement(36009..36656)
                     /gene="vex2"
                     /locus_tag="VUR04_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET5340019.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(36669..37946)
                     /locus_tag="VUR04_000038"
     CDS             complement(36669..37946)
                     /locus_tag="VUR04_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340020.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(38084..38368)
                     /locus_tag="VUR04_000039"
                     /pseudo
     CDS             complement(38084..38368)
                     /locus_tag="VUR04_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(38511..39110)
                     /locus_tag="VUR04_000040"
     CDS             complement(38511..39110)
                     /locus_tag="VUR04_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340021.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKMSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNDIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(39247..40131)
                     /locus_tag="VUR04_000041"
     CDS             complement(39247..40131)
                     /locus_tag="VUR04_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET5340022.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQNKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(40135..40521)
                     /locus_tag="VUR04_000042"
     CDS             complement(40135..40521)
                     /locus_tag="VUR04_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET5340023.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(40514..41857)
                     /locus_tag="VUR04_000043"
     CDS             complement(40514..41857)
                     /locus_tag="VUR04_000043"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET5340024.1"
                     /translation="MIKIYDTMSRDLRKFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(41939..42823)
                     /locus_tag="VUR04_000044"
     CDS             complement(41939..42823)
                     /locus_tag="VUR04_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340025.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(42835..43452)
                     /gene="cysE"
                     /locus_tag="VUR04_000045"
     CDS             complement(42835..43452)
                     /gene="cysE"
                     /locus_tag="VUR04_000045"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET5340026.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(43468..45681)
                     /gene="pnp"
                     /locus_tag="VUR04_000046"
     CDS             complement(43468..45681)
                     /gene="pnp"
                     /locus_tag="VUR04_000046"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET5340027.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVENLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(46366..47232)
                     /gene="metF"
                     /locus_tag="VUR04_000047"
     CDS             complement(46366..47232)
                     /gene="metF"
                     /locus_tag="VUR04_000047"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET5340028.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(47296..49545)
                     /gene="metE"
                     /locus_tag="VUR04_000048"
     CDS             complement(47296..49545)
                     /gene="metE"
                     /locus_tag="VUR04_000048"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET5340029.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLDTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHAPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKN
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(49806..50072)
                     /locus_tag="VUR04_000049"
     CDS             complement(49806..50072)
                     /locus_tag="VUR04_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5340030.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            complement(50198..50601)
                     /locus_tag="VUR04_000050"
                     /pseudo
     CDS             complement(50198..50601)
                     /locus_tag="VUR04_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            50757..51758
                     /locus_tag="VUR04_000051"
     CDS             50757..51758
                     /locus_tag="VUR04_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET5340031.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTETKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(51826..54231)
                     /locus_tag="VUR04_000052"
     CDS             complement(51826..54231)
                     /locus_tag="VUR04_000052"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET5340032.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVELPVADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVRAARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNAGSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILETLFTRLGLQVTYIATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(54308..54817)
                     /locus_tag="VUR04_000053"
     CDS             complement(54308..54817)
                     /locus_tag="VUR04_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340033.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(54817..55863)
                     /gene="pheS"
                     /locus_tag="VUR04_000054"
     CDS             complement(54817..55863)
                     /gene="pheS"
                     /locus_tag="VUR04_000054"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET5340034.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(56451..57866)
                     /locus_tag="VUR04_000055"
     CDS             complement(56451..57866)
                     /locus_tag="VUR04_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET5340035.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(57879..59717)
                     /locus_tag="VUR04_000056"
     CDS             complement(57879..59717)
                     /locus_tag="VUR04_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5340036.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLILPNNQTIEHSKELLVIL"
     gene            complement(59735..60574)
                     /locus_tag="VUR04_000057"
     CDS             complement(59735..60574)
                     /locus_tag="VUR04_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET5340037.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(60875..63450)
                     /locus_tag="VUR04_000058"
                     /pseudo
     CDS             complement(60875..63450)
                     /locus_tag="VUR04_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(63947..64750)
                     /locus_tag="VUR04_000059"
     CDS             complement(63947..64750)
                     /locus_tag="VUR04_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET5340038.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATVYHHTVDASTEEADLVSLRIVELLSRRGFRFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(65130..66875)
                     /locus_tag="VUR04_000060"
     CDS             complement(65130..66875)
                     /locus_tag="VUR04_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5340039.1"
                     /translation="MRFPHYKSLSLNSRINFNFPITLLVGRNGVNKTSILQALYGSPA
                     NKSVSEYWFSTNVDQIDEVDGKQCLIYSYYNIKASRNVEVLKGRSGTKKGLDYWEPYA
                     PQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFFYHYNFKKISTQ
                     RSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEIISEIMDESYTDI
                     QILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVNDIVNAQSNSLIL
                     IDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPREAVKLLVKNGEK
                     VDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSENLKQNLVVRYI
                     PGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLENGVVISDKIPES
                     DNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKYVSYLPFPTPEF
                     FLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQEQRRAVSKIQPE
                     SSMFQCIKEKLEALF"
     gene            complement(66943..68034)
                     /locus_tag="VUR04_000061"
     CDS             complement(66943..68034)
                     /locus_tag="VUR04_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET5340040.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDKDINVVSGDEVKEYLKIDTDDKLMLVACPPCQGFSTIGTNNENDERNQLV
                     FQFLRLINELNPDFLLMENVVGMTRTRNEKIFKKFLTSIDNNYSVIYDILNTADYGVP
                     QSRKRLVLHGIRKEILDNTNLTLNLPSKTHSNIPELDLLSWINADIIMDLPPIEGGEE
                     YIGEGIYNHVANKLSNLNIERITHIRNNGGSRTSLPKSLELNCHKNRLGHSDVYGILD
                     INKPSITITGGCMSYSKGRFGHPTQNRALSAREAARLQSFDDDYIFVGNRGQLAKQIG
                     NAVPVKLAQASGNYFMSVYREIANGQSDN"
     gene            complement(68115..70766)
                     /locus_tag="VUR04_000062"
     CDS             complement(68115..70766)
                     /locus_tag="VUR04_000062"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET5340041.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAIAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPEGDDWTQDSDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLPLEQATANVEKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKNLIRAVRNA
                     RAEVNVAQSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(70759..71337)
                     /locus_tag="VUR04_000063"
     CDS             complement(70759..71337)
                     /locus_tag="VUR04_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5340042.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDSTLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELEASLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNFQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(71337..71897)
                     /locus_tag="VUR04_000064"
     CDS             complement(71337..71897)
                     /locus_tag="VUR04_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340043.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAVFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVCSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            complement(71884..72333)
                     /locus_tag="VUR04_000065"
     CDS             complement(71884..72333)
                     /locus_tag="VUR04_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET5340044.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(72745..73140)
                     /locus_tag="VUR04_000066"
     CDS             complement(72745..73140)
                     /locus_tag="VUR04_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET5340045.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKEDGIKFK"
     gene            complement(73236..73490)
                     /locus_tag="VUR04_000067"
     CDS             complement(73236..73490)
                     /locus_tag="VUR04_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET5340046.1"
                     /translation="MSYEQEFMKEFEAWVNAQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(73500..74834)
                     /locus_tag="VUR04_000068"
     CDS             complement(73500..74834)
                     /locus_tag="VUR04_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET5340047.1"
                     /translation="MADEQIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(74834..75067)
                     /locus_tag="VUR04_000069"
     CDS             complement(74834..75067)
                     /locus_tag="VUR04_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET5340048.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(75517..75699)
                     /locus_tag="VUR04_000070"
     CDS             complement(75517..75699)
                     /locus_tag="VUR04_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340049.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(75701..76480)
                     /locus_tag="VUR04_000071"
     CDS             complement(75701..76480)
                     /locus_tag="VUR04_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340050.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVERSKFLVDKFSKELDPKDIPTL
                     LEQGPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(76759..77109)
                     /gene="rbfA"
                     /locus_tag="VUR04_000072"
     CDS             complement(76759..77109)
                     /gene="rbfA"
                     /locus_tag="VUR04_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET5340051.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(77360..80122)
                     /gene="infB"
                     /locus_tag="VUR04_000073"
     CDS             complement(77360..80122)
                     /gene="infB"
                     /locus_tag="VUR04_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET5340052.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAPKASAEKKAEKSEPVKPAVAKEEAKPAEPVAPKTEKVAAKPQSRNFKA
                     EREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQQ
                     GQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKEA
                     LAQANKRKEPEEIFEEAAKLAEQVQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRDD
                     YDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFHE
                     LPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYGI
                     EAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRVA
                     TGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDGV
                     MPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVEI
                     SAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTL
                     NVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEKS
                     ARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSAS
                     LQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVEI
                     RLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKVA
                     RDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAYV
                     MEEIKR"
     gene            complement(80139..80438)
                     /locus_tag="VUR04_000074"
     CDS             complement(80139..80438)
                     /locus_tag="VUR04_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET5340053.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(80431..80724)
                     /locus_tag="VUR04_000075"
     CDS             complement(80431..80724)
                     /locus_tag="VUR04_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET5340054.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(80746..81882)
                     /gene="nusA"
                     /locus_tag="VUR04_000076"
     CDS             complement(80746..81882)
                     /gene="nusA"
                     /locus_tag="VUR04_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET5340055.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDESDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(81926..82405)
                     /gene="rimP"
                     /locus_tag="VUR04_000077"
     CDS             complement(81926..82405)
                     /gene="rimP"
                     /locus_tag="VUR04_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET5340056.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(82531..83166)
                     /gene="trmB"
                     /locus_tag="VUR04_000078"
     CDS             complement(82531..83166)
                     /gene="trmB"
                     /locus_tag="VUR04_000078"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET5340057.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(83163..83957)
                     /locus_tag="VUR04_000079"
     CDS             complement(83163..83957)
                     /locus_tag="VUR04_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET5340058.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(84119..84730)
                     /locus_tag="VUR04_000080"
     CDS             complement(84119..84730)
                     /locus_tag="VUR04_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5340059.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMLYNSWLLLYYL"
     gene            complement(84881..85114)
                     /locus_tag="VUR04_000081"
     CDS             complement(84881..85114)
                     /locus_tag="VUR04_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340060.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(85156..85845)
                     /locus_tag="VUR04_000082"
     CDS             complement(85156..85845)
                     /locus_tag="VUR04_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5340061.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(85897..86280)
                     /locus_tag="VUR04_000083"
     CDS             complement(85897..86280)
                     /locus_tag="VUR04_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET5340062.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(86743..86904)
                     /locus_tag="VUR04_000084"
     CDS             complement(86743..86904)
                     /locus_tag="VUR04_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340063.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIVYMIAVMIYF
                     SLIKKKEKK"
     gene            complement(87201..87320)
                     /locus_tag="VUR04_000085"
     CDS             complement(87201..87320)
                     /locus_tag="VUR04_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET5340064.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(87323..87553)
                     /gene="blpU"
                     /locus_tag="VUR04_000086"
     CDS             complement(87323..87553)
                     /gene="blpU"
                     /locus_tag="VUR04_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET5340065.1"
                     /translation="MNTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(87797..88000)
                     /gene="blpN"
                     /locus_tag="VUR04_000087"
     CDS             complement(87797..88000)
                     /gene="blpN"
                     /locus_tag="VUR04_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET5340066.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYRRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(88016..88270)
                     /gene="blpM"
                     /locus_tag="VUR04_000088"
     CDS             complement(88016..88270)
                     /gene="blpM"
                     /locus_tag="VUR04_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET5340067.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            88550..90675
                     /gene="blpA"
                     /locus_tag="VUR04_000089"
                     /pseudo
     CDS             88550..90675
                     /gene="blpA"
                     /locus_tag="VUR04_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            90686..92047
                     /locus_tag="VUR04_000090"
     CDS             90686..92047
                     /locus_tag="VUR04_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET5340068.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            92104..92259
                     /gene="blpC"
                     /locus_tag="VUR04_000091"
     CDS             92104..92259
                     /gene="blpC"
                     /locus_tag="VUR04_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET5340069.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(92304..93644)
                     /locus_tag="VUR04_000092"
     CDS             complement(92304..93644)
                     /locus_tag="VUR04_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5340070.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYALFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(93658..94395)
                     /locus_tag="VUR04_000093"
     CDS             complement(93658..94395)
                     /locus_tag="VUR04_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340071.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(94400..94738)
                     /locus_tag="VUR04_000094"
     CDS             complement(94400..94738)
                     /locus_tag="VUR04_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340072.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     VQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            95014..95343
                     /locus_tag="VUR04_000095"
     CDS             95014..95343
                     /locus_tag="VUR04_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET5340073.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(95511..96560)
                     /locus_tag="VUR04_000096"
     CDS             complement(95511..96560)
                     /locus_tag="VUR04_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340074.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(96557..97288)
                     /locus_tag="VUR04_000097"
     CDS             complement(96557..97288)
                     /locus_tag="VUR04_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340075.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLEGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            97356..97766
                     /locus_tag="VUR04_000098"
     CDS             97356..97766
                     /locus_tag="VUR04_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET5340076.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSTSQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            97776..98063
                     /locus_tag="VUR04_000099"
     CDS             97776..98063
                     /locus_tag="VUR04_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340077.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(98797..99933)
                     /gene="dnaJ"
                     /locus_tag="VUR04_000100"
     CDS             complement(98797..99933)
                     /gene="dnaJ"
                     /locus_tag="VUR04_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET5340078.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(100335..100691)
                     /locus_tag="VUR04_000101"
     CDS             complement(100335..100691)
                     /locus_tag="VUR04_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HET5340079.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(100693..102516)
                     /gene="dnaK"
                     /locus_tag="VUR04_000102"
     CDS             complement(100693..102516)
                     /gene="dnaK"
                     /locus_tag="VUR04_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET5340080.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(102996..103520)
                     /gene="grpE"
                     /locus_tag="VUR04_000103"
     CDS             complement(102996..103520)
                     /gene="grpE"
                     /locus_tag="VUR04_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET5340081.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(103547..104581)
                     /gene="hrcA"
                     /locus_tag="VUR04_000104"
     CDS             complement(103547..104581)
                     /gene="hrcA"
                     /locus_tag="VUR04_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET5340082.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(104745..105254)
                     /locus_tag="VUR04_000105"
     CDS             complement(104745..105254)
                     /locus_tag="VUR04_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET5340083.1"
                     /translation="MNSRVEFRIFTIPDLDKEEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEVQVYMS
                     KGLKWEVMRSRLRSCTVAFSGGLVVCMSSFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            105861..108194
                     /locus_tag="VUR04_000106"
     CDS             105861..108194
                     /locus_tag="VUR04_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET5340084.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYSRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            108207..109670
                     /locus_tag="VUR04_000107"
     CDS             108207..109670
                     /locus_tag="VUR04_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET5340085.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            109670..>110362
                     /locus_tag="VUR04_000108"
     CDS             109670..>110362
                     /locus_tag="VUR04_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5340086.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILI"
BASE COUNT        32874 a        24126 c        19938 g        33424 t
ORIGIN      
        1 aagcacattc ataccatcaa aaatagtagc aataaacttg aacaactacc agaaacacga
       61 aaacaggcat aattgatgaa atatcagcgc tattaaacaa tataaataac cgctaagaat
      121 aaggcttaac ggttatcttc tacctatcta ttttttcaaa tcctcagtcg tttatctacc
      181 tataacctag gctttacgag tgccttgctc taccaactga gctaaatcgg cgattacact
      241 tacagtatag cactctgaga atagatgtca agtaatatta ttcaagcttt ttaatcaaaa
      301 tctgacaagg attttgcgga ttccatagct gagaaaaaat ctctaacttt ttaaagccaa
      361 gacctcgata aaagtcattt gttcgatcat aatctttatt agaaccttct gccactgttt
      421 tgacctgcag ataaccaact tttttacgag cttcactctc taaagtagca agcaattggc
      481 tcccaatttt tctaccttga taagcttttt tacgccgaga caatcaatct ctgcacaatc
      541 ttcactcgaa taggataagc ttacaaatcc agtcaaatca ctctcctgat aggcggtcca
      601 aacttgcagt gtcgtggttc cttctatata ggcttatgtg ctttctggga ttccaaacca
      661 ttctggcaaa tccttcaaaa cctcagcgac aactgccttt ttttgatttt catccttgac
      721 ttcttcaatt acaaacatca taagttcctt tcttgatttt agtcttactt tagcttttac
      781 gaacccgcac tttcgtagga atctaagccc ttatcccaaa gtttaaggga aataacaaag
      841 aaaaccagag aaatcaacat caaacctcct acgttaaaga acacatcctt ttcctgtaag
      901 aaatagctag ctggatagta ggctgtaaag gcgaaaggca cgataaagct aatcaaccaa
      961 cgaagaagag aattgtaaat agaaatcgga tacttagcaa agtcattgaa catatagaag
     1021 atgtaaatca tggcgcctga ctgcttagtc caaaaggcga tactggctgt tgcgatttta
     1081 agagaagtat aaatcaaggt cgcaaaagga atacaaacta ggaaaagcag gaattttgga
     1141 agagtccaaa caatgctggt cactgttgtt cccaataaaa taccaccgac taagagttca
     1201 cccaaggcat caatctgaaa ggtttcaact aggatgtgaa agagaggatt gatgggacga
     1261 gtcagatact tgtcaaactc cccttttcgg actaggcgtt gccctagtgc ccagagattg
     1321 tcaaaaaaga gatggtccat tcccttggga atcaaggaaa atccataaat gaaagctatc
     1381 tcttgaaagg tccagccttc taggaatgga atatgttgaa agatgacatt gagaaacaag
     1441 agattcaagc cttgagccag aaagactccc aaaacaccaa ccacaaaatc caccttatat
     1501 tccatgattt gtttgatgta ttgtctgata aaaatcagat gcattcgttg atattttttc
     1561 atactaacct ccttgaatgg tgataaagga ctggacccgt ttccaaatca actgagacaa
     1621 tcccaccatc actaagagcc agaagaactg caaaaggagt gcctgaagaa tctgactggc
     1681 atcgtatttt ccaacaatga tcataactgg agtataaatc aaggatgaaa aaggcaaaaa
     1741 ggagagaata tctgaaacaa cctttggaaa gaatgccaag ggaatcaaac tccccgacat
     1801 aaaagccact atggaagtct taagtaggtt ggaaccccaa agatttttaa acacaaaggc
     1861 tgaaaatcca aagcaaatat taaagaaaaa gttaatcaga taggcgagcg ttaagctaaa
     1921 aagataaatg acagttaatc ctagcacctc tacaatacct tgacccgata tgattttcat
     1981 caagacaatg acacttaaaa atggaaggcc aacgctgata aaaatcaacc acttggaacc
     2041 aagctcggtg aaaagatagg aggccgcaaa atgcactggt cgcaacaaac gcatgataat
     2101 ggagccatcc ttgacctcct ccccaatcat aaaggacgaa tcggatctag tcagaagatt
     2161 ggtcacaaaa ctcatgatga tgtagagggt gatatccgcc atactaaagc cctgaatcaa
     2221 agactcttgc gaagaatcaa agacagcctt ccagagataa aaggccacaa aagcccccat
     2281 gacatcgcca atccgataga gaataaagtt gactcggtaa gtaatcaact cctgaacccc
     2341 tgcattgata aagggtttat aacgtctcca caatttgatc atcctagagc tcctttcggt
     2401 agaagcgacg gataatatcc tcaatatccg tatccaccat cttcaaatcg cggatttcaa
     2461 aatcagacag ggtttgcttg ataatgtcag ctgactggta gcgagaacta tcaaattcaa
     2521 tgttgaggct gtttccttgt ctatcaatgg tcatatcaga cagaccttca tagtgagaga
     2581 cgagatgact ttgacctggg agcagttcaa aagagagagt cttcatctta ccaaaggtct
     2641 ccttgagttg gctcaccgtt ccatcaaaaa tctcttgccc cttgtcaatc atgaaaatcc
     2701 gatcacaaag ttgctcaata tcactcaaat cgtgagtggt caaaagaatg gtagtttctt
     2761 cctcttgatt gatctgagta attgcccgac gaatattatc cttaaccgaa acgtccaaac
     2821 caatggtcgg ctcatctaaa aaaagaacct tgggattgtg gagcaaggag gccgcaatat
     2881 ccgcccgcat ccgttgtccc agtgaaagag tccgcacggg atccttgata aagtccttca
     2941 aatccaagac ttcattcaaa aagtccatac gcttatgaaa gagcgagtct ggcacatcat
     3001 aaatctcttt taagacagtg taggtctctt gcagagccaa atcccaccat agctgggtgc
     3061 gttgtccaaa gactacgcca atatctttga cataatcttg ccgattgtcc tggggaatct
     3121 tgccgttaat ccgacaaaaa ccagatgttg gtttcaaaat tcctgtcagc attttaatgg
     3181 ttgtcgactt cccagcacca tttgccccga taaatcctaa aatctgccct tttggaacct
     3241 caaaggtcaa atccttgacc gcttcaaagg tctgcttttc aggatgaata aaggagcgca
     3301 aagccccctt caagcccggt tccttaacaa tcttcacaaa atgtttctga agatgttcca
     3361 cttctatcat tgccatatct atctccctat cataaggaat agcaacattg tgtttttaac
     3421 tacaaatatt ctaaatcctt actttctaca ccttctacat tttattacta cagaaggctt
     3481 tataccaacc tattatagtc caataaaaaa cagaatgcaa gcgtttgcct atggattgtg
     3541 aaattaggat ttctctcatg aaataatact tttaatcaaa aattctgttt aatagtttaa
     3601 attaccaacc tactcatctt ctcaccagag ggcggtatta actttgatca taaaatcgga
     3661 tactccctct atccagaaaa tatgctcaga atgattgtct ctaaacaata cctgctcttt
     3721 tacctcattc atgaaaaaga agtccatacc ctgagaatta tcaactcacg caccgactac
     3781 ctaaatcaac tcgaccacct ctttcgtaca tgtaggaaac tattttcctc acaaataatc
     3841 tcattataaa atccaataaa tttttttagc tcacttgaat attttctttg tatcgtttta
     3901 tcagcttcaa tctgatctag acttgttacc ttggaacgac ttgaaataac ctttgtaaaa
     3961 taacacttaa ggctttcatc atctcgtata aatttttcaa tagtgatata aaaagctttc
     4021 atattctgtt tgtaatcaga tattaattga ttaattttat cattctgatg aagattcgat
     4081 accataatat atagcggatt gaaataagat gagaacaaat cgattgggaa agtaaaatta
     4141 atttctataa atgttttagc aattgtttcg tactatttta gattcagtct actatacata
     4201 aactaacctc ctcattatta gcaaggcttc tactgattat aacctaattc ttagactact
     4261 tcaagactaa ctgtccaata ataatctaca gataaatcat ccactcttaa tcaaatttta
     4321 ttcaatccat ctactcattc ccaaaaggtt gctgtataat gcaagacatt tttcttactg
     4381 attttacttt tccttaccct caatttagtg agctaataaa ttattcttct tcaaaaggtt
     4441 gagatttatc tagtaactct aaaacattaa tggtaggtag caacattgct tcactgctat
     4501 caattgccga aactgttgaa acaatagaac gtaaataatg ataaagaata gcagtaccat
     4561 ttacgtatag aatatcggtg atattttcat ctatatttat ttcaaaatat cctattacag
     4621 ttacagatat ttttttcatg gcatctttgt caactaaaga aacactaagt tttacggctc
     4681 catgactata atcatctgca tgaccaacct taactatggg atataatata tcgaaggtaa
     4741 atgtgaacaa attgattagg gaatttaaac caacttctaa caatgtgtta tactcaatga
     4801 aaaccaaaga gcaaactagg aaactagccg taggttgctc aaaacactgt tttgaggttg
     4861 tagatggaac tgacgtagtc agctcaaaac actgttttga ggttgtggat agaactgacg
     4921 tagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
     4981 cgcacggcaa ggcgacgttg acgtggtttg aagagatttt cgaagagtat tagaaagctc
     5041 gatggactat tccagattca ttccactaga tttcgaaatc gagtagggga taatctctag
     5101 cccctctcac accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc
     5161 atgtcgttca aggtaataat ccaaacacga aaccagtcca cgtttttcaa ggactggttt
     5221 tgatatagca cgtttaagta ccgacttctg agctactata gtagattgaa actagaatag
     5281 tacatccctt cttctaaaac attgttagaa atcgatttgg ctgccctgat cgattcgtcc
     5341 tactcttatt tcattttact ataattgata gtggtcgccc cagccagata ccttatccgc
     5401 tatataggcc ttattatcac gttcctgttc gtagagccac gatttcgcta tcccttcctc
     5461 tgacgattct tatttcctgc gtcagacttg ggaatcgcta ttgggttcac cggtagcagg
     5521 tgcccaccga ggacttacac ctcagatata cgacatgccc gtcgtacatc aaaaaaagtt
     5581 gagacatggc gtcttcaact tttttacatt actttaacta ctgattaaag tgagtttacg
     5641 tcaactttga taccaacacc ttgagtagtt gtgatagtca agtttgttac gtaagttcct
     5701 ttagctgtag ctggttttgc tttttggatt gtttcgttga aagctttaaa gttttcaacc
     5761 aatttttcag cttcaaatga tactttaccg atgattgctt gaacgttacc tgcacggtca
     5821 gcacggtaag tgattttacc acctttagac tcttcaactg ctttagcaac atccattgtt
     5881 acagtaccag ttttagggtt tggcatcaag ttacgtggtc caaggacacg tccaagacgt
     5941 ccaacaagag ccatcatatc aggtgtagcg ataactacgt cgaagtccaa ccaaccgtcg
     6001 ttgattttag caacaaggtc atcttcacca acaaagtctg caccagcagc ttttgcttct
     6061 tcagcttttg caccacgtgc gaaaacaaga acacgtgaag ttttaccagt accgtttggc
     6121 aataccattg ctccacggat ttgttggtca gcttttttaa cgtcgatgtt caagttgtaa
     6181 gcaacttcta cagttgcgtc aaattttgca aagttagttt cttttgcaag tgctacagct
     6241 tcttctacac tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg aagttgtttg
     6301 ctttttttag ccattttcta ttctccttgt aagtggttca atcgattttc atctcccacg
     6361 tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct actatttttc tcttcctacg
     6421 gccttaagct cccttgctgt acccaagtac aaggctcagt cacttgccta gtatgaaaag
     6481 caactaatag actgctgtga gattttctac tgtgttattg attagtcaac aacagtgaat
     6541 cccatagaac gagcagtacc ttcgatcata cgcattgcag actctacgtt tgctgcgttc
     6601 aaatctggca tcttagtttc tgcaatttct tgtacttgtg cacgagtaac tgtagcaact
     6661 ttagttttat taggtgtacc tgatcctttt tcaacacctg cagctttttt caaaagaaca
     6721 gcagctggtg gtgttttcgt aacgaaagta aatgatttat cttcgtaaac tgagataaca
     6781 actggaatga tcataccagc ttggtcagct gtacgagcgt tgaactcttt tgtgaatccc
     6841 atgatgttga taccagcttg accaagagca ggtccaaccg gtggagctgg tgtagcttta
     6901 ccagcaggga tttgcaattt tacaagtttt tcgacttttt tagccatttt taaatcctcc
     6961 tttgtggttt tggcggtaat tagagatttt tacctcccac aagtatgttt ttcacatacc
     7021 cctccattat acactattta tctggaattg caagagaaaa gtttattttt tatactcaat
     7081 gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc tcaaagtaca gctttgagat
     7141 tgcagataaa actgacgaag tcagctcaaa acactgtttt gaggttgtga atagaaccga
     7201 cgcagtcagt aggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattaat
     7261 cgacgtagtc tccgccttca aagccatagt actcttccaa actgaggtca cttgcagcaa
     7321 tttctttggc ttcttttcca acgtagcgga gatgccattc ttctgccatg tagccggtct
     7381 ccttttcctt gcctttgaga tagcggacaa caaagccata gtcagccgca tggtccaaga
     7441 gccactgggc tgccttttct tcagtaacta aatcaccatc tgtcccaata aggtcaaaag
     7501 caaggcctgt ttggtgttca ctataacctg ggcgtgctga gtagcgatcc gctgcttcct
     7561 taccatcttg attgacatag tcttggtaga gcttagcctg agtttcataa cttctaaaac
     7621 cactgtagtg atcgctgatt gggtagccag ctgcttgcat tgctgcaatg agtttcagca
     7681 actctgcctt ggctgttgga ttttctcctg gattgtagtc ttttgacaaa ggatagtgct
     7741 tattagctat gacgatttca tcgtatttcc cttgaatact atagtagtct cccttattga
     7801 caacttctgc ctttttctga ctagatgctt gagatttgct acctacagtt ccttccggtt
     7861 gactgctttg ctccgtcttt tgagtatttt cttcaacttt cggtttttct tgcgaacaag
     7921 ctgcaagagt caatgctagt aaaccagata aaatgacata tctttttttc atttctttct
     7981 tcctctctct taggccaaat gcttctccaa ttcatgagat aagattttaa tcatctcttc
     8041 cagctctggc gattgtactt ggcaatcttc tgctgccatt tcttcccagg gcacccacca
     8101 gactgggcca cggccattca atccatgacc cttcatatca cctgttcttc gtggaaagag
     8161 atgccaatga gcgtgggcat caccatttcc taggagttca atattcatct tttcagcctc
     8221 aaatgctttg gcgactgttt cttggaccaa actcatttcc tctaaaaagc gaaattttac
     8281 aggattctcc atatggtgga gttctgtaac atgctctttt gctaaaaata aggtatagcc
     8341 cttgaagtat tggtgatccc caataaccac atagcctgtt tctagttctt taacaaagta
     8401 gggattttct ccagctttga tgagttcgat tctctgacag attaagcaca ttctatgata
     8461 ccccctcgct cttaagataa gcatcaacca taagctcagt cgctactact gaatcgatgt
     8521 gggtgcgctc ataagagtga ctggactcaa taccagctcc aagaagtgca tgcttgacct
     8581 ccgcgcctgc tgacatcgct gctgaagcat ccgaaccgta aaatggataa atgtcgagct
     8641 taaatggaat atcttgctcc ttcgccaaag ctactaagtg ttgacggaag tcatagtgat
     8701 aaggaccaga agcatccttg acacagatag atactgtgta ctcatccgtc tgttggtcat
     8761 cccccattgc acccatatcg acagccaggt actctaccac ctcttttgga atatttgaat
     8821 tggcaccatg gcccacctct tcaaagactg aaaaggcaaa atgtgtcgtc atcggcaagt
     8881 cgattctctc ttctttataa actcgaagga gattgagcag aattgctgcg ctgactttgt
     8941 cgtccaagtg acgggacttg ataaaaccag tctctgtcac gacagtacgt ggatcaaagc
     9001 tgataaaatc accgacctcg atgcccaagg cacgcgtttc tttttcattg gtcacttttt
     9061 catccaaacg cacttccata ttgtcctgag tgcgttcagc agttcctgca tctttgtaga
     9121 catggcaaga tgtctggtgg atgaggatcg ttccagatac cgttttacct gtactagcta
     9181 catgaacagt acagttttct ccctcaatca tgttccaagg aaaaccaccg atacggtcca
     9241 atttgagacg accatctggc ttgactgcac gcacaatggc tccaagtgtg tccacatggg
     9301 cagttacata gcgatgttct tcgtcgtttt gacctttgat ggtcacattg acaccgccct
     9361 tggctgttcg aacaggctgg taaccaaaac cttctagagt cttgactaaa taattcgaaa
     9421 tttcacgagt aaagcccgtt ggcgatgcga tggctgtcag ttctttgata tattctactg
     9481 tttgattcat ttcttcacct ctttcgctac ctattataac acatttatca tcggataaaa
     9541 aaagaaaatc actcctgtag acttggctac aaaagtgatt taagtgatta ttccatttca
     9601 aaaacatcgc tttcttgctt gtttggtaga accaatgaga gcaagattcc aacaatggct
     9661 ggcaccaacc atgggagaga tgccttggca aaaggaagaa cgctaacaag atttgcaaga
     9721 aactcaacct taaacgagct tcctagtacg cttgcaatgg caataactgt aaccacagca
     9781 attgtcaact gcatacctgg ttttgaaagg gcaacaaatt tgttgacaat gacaatcata
     9841 acgatagcaa tcgtgattgg gtacaagata accagtactg gaattgagta cttgataatc
     9901 gcatcaagac ccaaattggc aatagcaaat ccaatcaagg taaaggctgt cgcataaacc
     9961 ttgtagctga tttgtgggaa gcgctcatta aagaactcag ctgttgacac aatcaaacca
    10021 acagtcgttg tgaagcaggt tacggtaacc atagctgcaa ggaagagttg agctgttgag
    10081 ccaaagattt cttgagtggc ttgtgacaag atgtaaacac ctggtgttcc acccttcatc
    10141 gcttcagctg gtactgggaa atgatttcca agaaaaccta aaccgatgta aagagcgctg
    10201 aaggcaaggg caacaacgat accaacaacc caaatagttg aaatgtattc tttcttactt
    10261 gaaaatccaa gttgtttcaa ggtttgaact gcgattacgc taaaggccac tgaggcaagg
    10321 gcgtccaaag tattgtaacc ttctaggaaa cctgtaccaa aggcagaagc ttgataagca
    10381 gctgaagcag cttgaggact tgttccacca tatttgatag ctcccagaac gaccaagata
    10441 acaatcaaaa ttgcaaagac tggcgttaaa atacgtccaa tgcggtctaa gatttttgat
    10501 ggattaagcg aaatcaaata ggctgccgca aaatacagaa ccgtaaatac aatcaagcca
    10561 agtcctttat ttgcatccga caaaaggggg ctaatcccta cttcgtaagc tgttgtagca
    10621 gtacgtgggg tagcaaagaa tggaccgatt gacaagtaaa gaactgagag gtaaagagtc
    10681 gcaaaccaag gcgctatctt cgttgaaatc tcgtagatat atcctttagg atttagcgtt
    10741 ccaataataa gagtcaagac ggcgatacca acgcctgaaa agacaaaacc tgcgatggca
    10801 ggaagaaaat gttctccaga tagagcacct agagaaggcg gaaaaatcaa gttccccgca
    10861 ccaaaaaata ttccaaacag gagcaaacct gttagggtac cttttttagc cataaaaatc
    10921 tccttcatat ttataaaata ctgacctagt ataccacgat taggagtctg aaaaaagcat
    10981 cacgaggcaa atattaaatg ttttcaattt tcttaaaaat aagaattatc taaaaataaa
    11041 actctcctac ccagtccaca ccaagtagga gaaatgcaaa attttaaagt tcttcaaagg
    11101 ctaacatgcc accctggaca ttgataacat tataaccttg ttctaatagg aattggcaag
    11161 cacgcgccga tctcattcca gatttgcaaa taatataatg caagcgatct ttatccaatt
    11221 aatcataact atcagccaat tgactaagcg gtaggttgtg ggtaccttct aaatgaagag
    11281 ctgcaaactc atccacttct ctaacatcca ctagagaaag ctggtcgttt tggtaaagct
    11341 ggtaaaatgc gtcaaaggct atttctttca ttctttttct tctaatactc ttcgaaaatc
    11401 tcttcaaacc acgtcagcgt cgccttaccg tgcgtatgtt accgacttcg tcagttttat
    11461 ctgcaacctc aaagctgtac tttgagcagc ctacgactag cttcctagtt tgctctttga
    11521 ttttcattga ctataaaatg gttttaattc tttttttcaa atctggcact acttctgcct
    11581 caaaccaagg atttttggtc atccagattt gatttcgtgg tgatgggtga actagcggaa
    11641 aataggctgg cagatagtct ttatagtgtt tcaccctctc cgttaccttc ccactgattt
    11701 tctcctgtaa atagtaggct tgggcatatt gcccaatcaa gagggttaac tgaatatcag
    11761 gcaattcctg taagagctgc ggatgccatt tttctgcaaa acctgtacga ggcggaagat
    11821 cacccgactt gccatgtcct ggaaagtaga aatccatagg caaaacagca aaataacctg
    11881 aattgtaaaa ggtatcttca tccacaccta gccagtcccg caaacggtca ccacttttat
    11941 ctttccagta aaggcctgct tcttgagttt taagtcccgg agcctgaccg atgatattga
    12001 tgcgagcagt ttttggcgct gcaaagagag gctcaatgcc acgctctgta tagctggcat
    12061 tctgcgaatc cgccatgata gcctgtttga ttctttcgat ttgagacatc tactttccct
    12121 ccaaaaagaa gtccaagcat aagatctcag acttctatcg ttttatttga tcaattcgta
    12181 aatagcttcg gcataaattg ctgctgctcg gaagagatcg tccaaggcaa taaattcatt
    12241 ggcttggtgc atggtatcaa ttgagtctgg gaacatagca ccataggcaa ctccgcgctc
    12301 taacaagcga ccaaaggttc caccaccgat gacttgttca tgacctttaa ggcctgtttg
    12361 tttttcatag acattcaaca aggtttgcac aagtggatct tccattggca catagtgagg
    12421 ggtatgacca tgttctgata gactgacaga agcaactggc aagttttcta ggattgactt
    12481 gatttgttct ggacttgttc cttttggata gcggatgtta agggcaatgg tattatcagc
    12541 acttgtttca tcgaagcgga agacgccggc attcatagaa agagcaccca tcttttcatc
    12601 cacatgagca atcttgagat tttcaccctc atgatcgttc aagagaattt tacctgcgat
    12661 gtcaaggtag tctttggctg gaccagcaaa gccaaactgg ctgaggaaga gggctaggta
    12721 agtcgcacca ttgacacctg aagcaggcat agcaccgtgg gctgatttac caatgatcgt
    12781 caccttgtat ttgccagctt cttcttggag ttctcctcta agtttgtgtt ctgcaacaaa
    12841 ggcatctagt ttagcttgca agtcagccaa atcacctgaa acgactgctg ttgctgattc
    12901 tggtaccata ttttcacgta aaccacctgt aaagctgtga agacgggcag cacctgtatt
    12961 ttctcctgca aagtggaggt attccgtgat atttcctttt tcaccattga tgattggaaa
    13021 ttcagcatct ggtgagaaac cgaaatctgg tttggcaagt cctacgtgct caaagtagta
    13081 gtccatgtct gcccagcctg attcttcgtc tgttccaacg atgaagcgaa ctttcttaga
    13141 agttggaaga cccaattctt tgatgatttt caaaccatag taacaagctg ttgtaggacc
    13201 cttatcgtcc gaagccccgc gcgcataaag gcgaccatct ttgatagttg gtgtgtaagg
    13261 atctgtatcc caaccgctac cagctggaac cacgtccata tgggcaaaga ttccgagaac
    13321 ttcttctcca tcaccaaact caaaatgtcc tgcatagtta tcaacatttt tagttggata
    13381 accatcacgg tctgcgattt caaggaattt ttccaaggct tttactggac caggtccaaa
    13441 tggatgttgg gcatcagcct tgctatcatc acgttctgag ttgatttcca aaaggctaaa
    13501 caagtcagcc aagaggtctt ctttgcgttt ttctacttct gctgtaaaat caattgctat
    13561 cattttttct tcttcctatc ttttttcgat gatttcatct actggcaagc ggtagcttgg
    13621 ttccaatttg tcgtctgtgt aacccactgt gatcaagagt tctgggcgga aacggtcttc
    13681 gatttccaaa acttcattaa cttttgattt gtcaaaacca agaataatgt tagaaccaat
    13741 tccttggtct gtcaatgcaa gaaccaagtt catggcaacc aaacctgcat tgagagctag
    13801 gtagtcgctg acttgttgct cactgtaacg ggcaaactca gctggcagat ttttcataaa
    13861 atattgaagt tgctcttcag aaaagttatt agcaccacca acacgggcaa tcttacgagc
    13921 acgtttggct aagtccgtat ctgtaaacaa ggcaatggtt acaggcgctg atgatacctg
    13981 ttcaaaattg gaaccataag ctaactttgc cagttcagca tttttctcac gtaccaccac
    14041 aaatttccaa ggctggctgt tgtgggcgct tggcgccaag gttgcaattt cgatagccgt
    14101 acgcacatct ttgggatcaa caggcttatc agtaaaatgc ttagtcgcat gacgtttttt
    14161 atttaattca agaaatttca taatcgattt ccttttctaa ttctactgct tccattctac
    14221 cataatttga aagagcttgc agggattttt catgattaag tttttctatc acagacataa
    14281 aagatatata ttggtttatc aggaaagttt ctgataaact agcaagtact ttacatttga
    14341 atggagacag tatgaaaaaa tttagcctat tactagctat cctaccattt ttggttgcct
    14401 gtgagaatca agctacaccc aaagagacta gcgctcaaaa gacaatcgtc cttgctacag
    14461 ctggcgacgt gccaccattt gactacgaag acaagggcaa tctgacaggc ttcgatatcg
    14521 aagttttaaa ggcagtagat gaaaaactca gcgactacga gattcaattc caaagaaccg
    14581 cctgggagag catcttccca ggacttgatt ctggtcacta tcaggctgcg gccaataact
    14641 tgagttacac aaaagagcgt gctgaaaaat acctttactc gcttccaatt tccaacaatc
    14701 ccctcgtcct tgtcagcaac aagaaaaatc ctttgacttc tcttgaccag atcgctggta
    14761 aaacaacaca agaggatacc ggaacttcta acgctcaatt catcaataac tggaatcaga
    14821 aacacactga taatcccgct acaattaatt tttctggtga ggatattggt aaacgaatcc
    14881 tagaccttgc taacggagag tttgatttcc tagtttttga caaggtatcc gttcaaaaga
    14941 ttatcaagga ccgtggttta gacctctcag tcgttgattt accttctgca gatagcccca
    15001 gcaattatat cattttctca agcgaccaaa aagagtttaa agagaaattt gataaagcgc
    15061 tcaaagaact ctatcaagac ggaacccttg aaaaactcag caatacctat ctaggtggtt
    15121 cttacctccc agatcaatct cagttacaat aacactcttc gaaaatctct tcaaaccacg
    15181 tcagctttat ctgcaacctc aaagctgtgc tttgagcaac ctacggctag cttcctagtt
    15241 tgctctttga ttttcattga gtataagata tactaaaagc gattggctgg tccaatcgct
    15301 tttttagttt gcattggcta ttttaggaaa ctcttacaaa aaatcaaaaa aattcttcac
    15361 atcctctaca tacccatgct tttctattaa gctggctaat aattccagat tgtgcccctg
    15421 atagttatcg tcacgacgca gttcttcata catttcgata aagggaagcc ccttggactt
    15481 ggccaattct aactcagctt cgtaatcata agcaacttta cgaaattgga tattgagtaa
    15541 ttccccatct tcaacttcta tcacggcata ctgggcacgg tgatttttta acgcctccca
    15601 attaaaatag ggcatgccaa tcgaccctgg attgatgatt tgttgccctt gacttccata
    15661 acgaagcaac tgcttgtgaa catgaccata aactgccacg tccgtttccg catctagcag
    15721 ttggtcaaat ttctctgtat cattctcaac tagcaagtca ccaccatagt ttttgtcagg
    15781 taaattatga gagatagaaa agcgcaatcc gtcaatttct ttcttttcca gcaaaggcaa
    15841 gcttcgtagc cagacaatcg ttgcaggatc cattcgctcc atcaaatact gtgtcatacg
    15901 caagagctga acttcctgtg ggtcttctaa gccatattgc ccatctaaag cctcaaggac
    15961 acgatcatcc caattgcctc gaacacttgc tgtgatagga aggtccttta gcagggcgac
    16021 taagtcattt gcgcctggac caggaagaaa aatatctccc agaagccaat attcactggc
    16081 cccttgattt ttagcatctg caatcactgc ttctagcgcc gtcgcattgc catgaacatc
    16141 tgataaaatt gcgattttat ggttcattgt ggtttccttc cgtttggtaa tctactcttt
    16201 cttctgctac ttgaggcaag gcttctccct gcgggttcaa ctttctttgc acagcctctg
    16261 caacgactct aggtacccca acttcgacaa tctcatccac actggcttcc ttgattttgg
    16321 tcaaagactt gaaatgcctc atgagatttt gcttgcgttt aggtcccaga ccatcaatcc
    16381 catccaattg agatgagaaa gaatttttgg agcgcagttg gcggtggaaa gtgatagcaa
    16441 agcggtgcac ctcatcttgg atgcgttgga ggaggaaaaa ttcctgagaa ttgcgagaca
    16501 agtccaccac ctcaagcgga tctccaaaga gcaattcatg ggtttggtgc ttatcattct
    16561 tttgcagccc agcaattgga atatccaagc ccagttcctc ttggataacc tgcttagcga
    16621 tattgacttg accttgcccc ccatcaatca caatcaaatc tggaggagtc aaagcctcac
    16681 gctgtactcg accatagcgt ctgcgaatga cctctctcat gctggcatag tcgtctggtc
    16741 caacaaccgt ttttatcttg tacttacggt aatccttctt actcggttta ccgttgacaa
    16801 agaccaccat agccgaaaca gggctagttc ccatgatatt agagttatcg aaggactcga
    16861 tacgtactgg ggtcgggatt tggagcaaac gccctagatt ttcaatagct ccttgagtct
    16921 tttcgacaga tttttctagc agattgaact tctgctctag actaacacga gcatttttta
    16981 tggctagatt gaccagttgt tttttctctc cacgttgagg cttaagaatc ttggaatcca
    17041 ccaaggcctt gacagcctct tcgtcaatat cctgcggaat cagtacctca ttgggaacta
    17101 gatgagattt ttcttgatag aattgtccta cataggtcaa aaaatcctca tctggatcat
    17161 tgaagtaggg gaagagattg acatcgcgct cgataagctt accctgacgg acaaagaaaa
    17221 cctgcacaca catccagccc ttatccacat agtagccaaa gacatcgcga ttttgcaaat
    17281 ctttcgccat gacccgttgc ttggttcgaa gcgttccaat agcctgaatc aggtcacggt
    17341 attccgccgc acgttcaaac tccatacttt gtgctgctac tgccatttta ctcttgagat
    17401 catcgatgat tttgtcatcc tgacctttca gaaaatcaga cacctcctga gccatagact
    17461 tgaaataagc ctcatccttc ttacagatgg tgtgggccat acactggccg atatggtaat
    17521 aaaaacagac cttagagggc gggttggtac attttcgaaa agggaaaatc ctatctagaa
    17581 gtcgcttgat ttcattggct gcccccacat ctggataagg gccaaaataa agaccaccgt
    17641 cctttttgac ctgacgagta atgataagcc gtggatagcg ctcattggtg attttgatga
    17701 aaggatagga cttgtcatcc ttgagcatga tattgtactt gggcttgttt tccttgatca
    17761 ggttgatttc taggagaagt gcctcaatat tagactccgt aacaataaat tcaaaatcca
    17821 caatttcaga caccagagcc tctgtcttgg tatcatgact tccacgaaaa taggaccgta
    17881 ctcgattacg cagattttta gcctttccta catagataat ggtgccattt ttatccttat
    17941 gaatgtagca accagggctg gtcggcaaga gctctagttt tgatttaatc aagttgttca
    18001 tagttccatt atagcaaaaa aagtagggaa agatagtacc ctactcacta gtctcatata
    18061 tttttcggag gtttgcaaca tcctcttcct ggataccata aaaggaacct gctggttgca
    18121 tgacagactt ctcatctgta tggtccaagc caatcgcatg acctaactca tgttctgccg
    18181 tatggacaag gcgttcatag gagtagccat agtatggatt ggacaaataa taatgattca
    18241 accgcaccgt tacggacaag aattgccctg ttaagagatt agtttgactt tccgcctctc
    18301 ctgccacagg agtgcctccg tcgttcatct ccgtagccgt aatatccgcc ttactagact
    18361 cagtcacgag ttcaaagtta aaagcaccag tttgattcca gttctggatt gcttctaaat
    18421 aagcctcttg aaagcgtgaa tccatctgcg gatccaggta aatacgagca gaggcctgtg
    18481 cccaccttcc ttcagaatgc tggtgactat ctgtctggct taacttaggc agttgccctg
    18541 ttttctccca ttggtcaata ctttgttgac caatttttac tgaccgttct gcttgcttta
    18601 gcgctccttg aaaatccccg ttcagatacc agagaagtcc gaaagcaagc acacataaga
    18661 gcacaactat ccaaaccaga cgccaaaaca aacgccacac aaaagaaaag aaagccccta
    18721 tcaaacgaaa aagccagcgc atgtctctcc acctttctag caaataagaa ttattttact
    18781 aaaagaagct aaaagaaatc taaatactga ctttttcatc ttaacgtcct actatttttt
    18841 tgagtaactg gatagctttg tattttaaag gcgatggatg gtaacggaaa gtacccgctt
    18901 tgcgtacaat atagccatta aaattctgtt taaaacgcaa aacaccatca cttccatcaa
    18961 aaatcccttg aatgcctagg aagttgtatt taggtattcc acgttttatg ctttccaaca
    19021 taacatattt ttgaagcagg gcaggggcat agaacttatt aaactcagtg taggaaccac
    19081 taaagagata agtcgtttcc tgaggcatat aaacaaataa actcccagct aaaacaatat
    19141 cttcttctcc atatttttca atcaagtctc gcgcttctgc ttttcgaact tcaaacgttt
    19201 caaattgact agaatattct ctcagttgat tttgtttttt ctcagaatga ggatttttac
    19261 tcaaatcaag tcgcaacttg tccaagtttt cttctagttt actttgttca ccttgcaatt
    19321 tgctcatata gtccgaaaaa tttaagcttg ctatgagaaa ctccgcttgt tctccaaaaa
    19381 tatcataaaa atgctcataa tattctaaac ttttatcact atattctcta cgttcagagg
    19441 tttcttttgt tatattctta aaaatcgata gttcttcacg ttttaacttt ttcaaccgaa
    19501 tgccaaaggt ttcagccttt ttcaccaagg gtttaccctt tttgctaaaa cttttaagca
    19561 aactcttttc agttaattca gttaaatctt tatagtataa ccaatctggt tctccacctg
    19621 ggtaacctgt tgttaagcca tcaaattgat aacctaaatc agtcaaacct tgaataatac
    19681 tttttttctc agcatctatt gaattacctt ggctatcaaa agtttgataa gtttcataag
    19741 gttttacaag caactctaat acaccatttt gcttggcata ttcttttaac tctgcataaa
    19801 aaactggaag agcatcttgt tgggtataaa tcggccccga attgagttcc atatgcagac
    19861 cacccagcat gggcaagcta taaaccagag ctgcaacttg aatttctcct tcttgtttca
    19921 aagcaagata aacaattcga gcccctcttt tttctagcaa atcccccatc tggacagatt
    19981 gcataaagga acgagaagaa acctgatcag aataagtctg aaactcttct ttcgtgagtg
    20041 ttgttagtgc catatactta ctttctatgt ttttttctta atgttttacg gaaatcaaga
    20101 gcaagtctta acagaggata gagaggatga gtgggcattg taaattcacc caagtattct
    20161 tcaatcgttg gattaaattt ttccttaaaa tgataaagtc caccattgag agagttttca
    20221 acaccaccta aattttgcca aaccatacct cgctcaaagg catagcgagc cgtttcatac
    20281 catgttaaaa ttggtgcatt gtaacgttta aaatcatcat ccataccagc atatatattg
    20341 acagaggtag taccaaattc caaactcaaa gtagccgcta aaggaactct cgcttgacct
    20401 acatctatat attcctgcaa gaaggtcaat tcctctaaca aacgttcttt ttccttcttc
    20461 tgcgcttcta cttttgaaat tcgagtcgac tcagtaaagg tctcttccaa ggctctattt
    20521 ttcgctaact gttcttctaa ttcttgcgaa cgtttagaaa catccaaggt ggccaaggtg
    20581 atataggcct tgtccttaaa attatctaac aattttttat aataggcttc attcctcaaa
    20641 tgaatctctt ttcgcttctc agtttttttc atcaactccg aaaatgaatc taatagttcc
    20701 agtccaccat attgaatctc aagccctttg tttcgtgctg ttcgaatagc ctgttttgtt
    20761 gacttggaaa gtttatcttc ttcaaaattt tccttgtata ttttcgcctg aatacgaggt
    20821 tgaatggtgt ctcccatttc ctccgttttt cctgaccacc ttactcccat ttgttgcaaa
    20881 ctatcaataa tagccagatt ttcaggaaat tctgtctttt cctgattgat taaactttga
    20941 gataggcaaa tacttgggtc aaaagtcaca aaaaccgctc tcttactgcg agcataggac
    21001 ttaatagact gaatgacaaa attcaagagt tctttatccc cataatccaa tataggtcct
    21061 cttgggatgt aaaacatttt atagcctagc ggaagagttc taatcaaaat actagctgtc
    21121 gccagtaatt tttcttccct gtaaacacca aacttctcat gttgccaatt agacttaact
    21181 tcctcccaag cactactttg taatacattg actaattcat gttctttgac aaactgatca
    21241 tattctaatg tgggaatgcc aatttgataa cggtacattt cctactctct ttcctccagt
    21301 attttattac tattctacta ctttcgtttg aaaagtctag tgaaaacata ttttatttta
    21361 gttctactcc ccctatgctg aagttcaaac taagtcagtc tctcttctaa tttgaaatca
    21421 attggtaggg ttgttaaaaa aacttccaat tgtttttccc agtagtacca ctcgtgagtt
    21481 ccagcgctat ggctataggt cacatcaaaa cctagttttt tgagattttt cactgcgaga
    21541 ttattggctt cgtacaagaa atcctgttcg ccacaccacg cccaaagttt ggtcttttta
    21601 tccgattttt tagccagact ttcaagagaa tagggactag ttgtccagtc tttaatctct
    21661 ccaaaaacac ctctccagta ggctggactt cccagatttt gactttcagg agaaaagttt
    21721 tgaaagctga gggcacctga aaaactagct gcatgagaaa aacgatttgt cgtaagagcc
    21781 agtttgaagc agccgtagcc tcccatagaa agaccagcga taaaggtctt ttcacgcttg
    21841 ctagtcatat tagggaagaa gcgtttcaga acctgtggca attcctctgc tagagccgtg
    21901 tagtagtcaa aaccatactg ggtatcggtg taccaaccat tgctggtatt gggcataaca
    21961 acgatgagat tagttcctcg aagcaagcgt tctacattgg tccgcttaag ccaactatta
    22021 tgatttccag acatcccgtg caaaaggtac aagacgggaa tatcttcaca ctctggttct
    22081 tccactcgat tggcatcagg gtagaggaca ttcacccccc actccatatc caatacttgt
    22141 gagtaatact cgattttcat tactgccatg attttctcct tctatttttc tataagaaaa
    22201 agccgaaact cgactttctc tctgtttatt tcaacgatta ttttgcttcc atgactactg
    22261 gtaaaatagc tggacgacgc ttggtttggt caaagagata cttggtcaaa ttatctcgaa
    22321 ccttcccttt aagatctgcc cagtcaaagt catctccttg aagatactct tctaccgttt
    22381 ggttaatcaa ttctgaactt tcacggagaa tatcgcgact cttcttgaga taaacaaatc
    22441 cacgcgtgtg aacacgagcc ctagccacaa ttttcttctc acgacggttg actgtaatag
    22501 ccacgatgaa aattccatcc tctgacaaga ccttacggtc acgaagaaca acatttccaa
    22561 catcaccaat ggcattccca tcaatcaaga tatctcctgc tgaaaccgat ccagctggaa
    22621 caaagtctcc attctcgtaa gccatggtcg tccccttttt aggaatgaaa atgcgttctg
    22681 gcaacatccc aactgccatg gcagccttag cgtgagcatc caactcacga tactcccctt
    22741 ggacagggaa gaggtactta ggttgcaaaa gattgatcat cagctgcaaa tcacgcacat
    22801 ttccgtgccc tgatacatgt aaactttggg taatcaattt gacaacccca cctgcctgat
    22861 aaatcatatt ttccacacgc gcaacaaagg cttctttagc aatagacgga gccgtagcaa
    22921 tatagaccag gtccccatcc ttgatttcta cataacgatg gcgaccaatc gacatcttac
    22981 gaagtccatt gataggttca cccatacgac ctgtctcaag aataatcaac tcatggtctt
    23041 caaagcgaga catatcttta ggcttaatca agagaatttc gttggctaaa gacaacttct
    23101 taagacgaat cgctgtgcgg acgatatttt caatatcaaa tcctgtcaag acgatacgtc
    23161 gacctgtttt atccgcagcg tcaaaaatct gctgaatacg agaaagatta ctggaaacag
    23221 ctgcaacgat gatacgacct tcccagtcag caatagtttg ggtaatttca tccctaactt
    23281 cactttcact agccacctga atattgctgt ctgcattggc cgaatcactg aggagagcca
    23341 ggacgccgtc acgaccaatc tctgccaaac gagcaaaatc agttgcataa gattcactag
    23401 ccgtttggtc aaatttgaag tcacctgtat aaacgatgct tccttccgat gtcttcaaga
    23461 caattcccag actctctgga acggagtaag tcgtagggaa gaaggaaacc actgtcccac
    23521 caaaatcaat ctccgtattc tcatcaatga catggaaatc attaaatttc ttaacggcat
    23581 catttccttt gacaaagagc tttgccaact caatggtcaa ctcagaccca aatacaggaa
    23641 ctttagcctc tgccaagaga taaggtagag caccaatagc atccgcatgc ccgtgggtca
    23701 agaaaacccc agcaatacgg tcgctatttt caaaaaggta atccatgttt ggaatcacca
    23761 catcgacccc taattgttca ttttcaggat attttaaccc tacattcaaa acaaaaatgg
    23821 actctccaat ttcagcaatg tacatatttt ttccattctc acgcacacca ccaagtgttg
    23881 ttaaactgat attactcatt tttcctccaa aatcttagtt tatcttgatt atagggcaac
    23941 tctaccctct tattctaaaa gttctgatac tttcagccga atcttttcct accattatac
    24001 catttttttg atgattttca aaatgaaggt ctgttttcaa aaaagagttg atttcccaac
    24061 tctttcctaa cttctactct ttttccatca aaaaatcata aatttcttgc accgtaccca
    24121 gcgccatcat ttcttggtct ttaacggttt gtttgagatt ttggtaaatt tgactttctc
    24181 ctatctcccg ctttggcgcc tctttattga ctgtcatcac accatctttt atcgtcacaa
    24241 agcctagttc ttcaaatact tgaatcatct tgaccagcaa gatttgttga atattaagat
    24301 atgcagccaa atctttcagc ttgtagcgaa tatcaaactc tgggaactgg taaatagtct
    24361 tgtacaattt agcaaactga tctctagtcc cataacctgt cagataatag gtcttgtcaa
    24421 tatcattttt gaaatagaca gcagagaaat gctgttcctg aaaaatggtc ttcagctgag
    24481 taatatcctc tggaatgttt tttacgacaa cagcttcact agccgcaaga tttggcagtt
    24541 ctccaggaaa atccaagact ggaacacctt ctggcaagac tgcatttttt ccacgaatgt
    24601 taaaaagttg aacaccttcc actcgcgcat ccaccatcat caactggagg gcagtttggc
    24661 cattccattg gttgacagac aatttaaccg ctaactctag attcttggtt tgagaaaact
    24721 ctgtcgccca tctgccttga ccaaaggcta ccacttcaaa actcgcctca cccttggaaa
    24781 ttttcagctt tagatgggca ttacctgccc ccatagtacg agcactttcg acctgaaaat
    24841 tcttgatata aaaaataggt ttctgattat ccattccaaa aggagctaaa cgttcaaaac
    24901 ttttgaccgt ttccaagcta agtgcctcca aatccaactc ttcatctagg tttaacttat
    24961 tcttgccacc agcatctgca cctttttcac gaacataatc ttccaaaacc tgagataaat
    25021 ctgagagttg ctcaacttcc agcgtcatac ccgctgcacc tgcatgacct ccaaaggcga
    25081 tgaagaggtc tcgatgggga tccagagctt caaaaatatc gaccgcttcc acactacgag
    25141 cactgccctt ggcacgaccg tcttctatat taagaacaat gactgtctgt cccaattctt
    25201 ccaataaacg accagccacg attcctagaa ccccaggatt ccagccttcc ttggccaaga
    25261 cctgaacctt cttctcagga tccaccatgg tcttggcttc ttcatagata gactgaacga
    25321 tttccttgcg ctcttcgttt ttctggtgaa tcataagggc aatctcatgc gcttcctcat
    25381 catcaaatcc agtcaacaaa tcaatggcag gattgggatc atccaagcgg cccaaggcat
    25441 tcaaacgagg agcaatctgg aaaccaacca tttcttctgt tacttcgttg gcagcaatcc
    25501 cagccatgtc cagcatttct tgcagaccaa tgcgctgggt atgacccaac atttccagac
    25561 catattgaac taagatacga ttttcatccg tcagactcac catatctgca atagttccaa
    25621 tagcgaccaa atcaagcaat tccacttgca cttcttctaa cagggcacaa gccaacttga
    25681 aagcaactcc acaaccagcc aaatatttaa aaggataatc cgcatctgga tgttcaggat
    25741 ggacaatagc ataagcatct ggcagggttt caggcatgga atgatggtct gtcacaatga
    25801 catctactcc catagactga gccaatgcaa tagcctcatg accagcaacc ccattgtcca
    25861 ccgtcacaat caaggaaatc ccttcttgct cgataaagta tttataaaca ctagcattag
    25921 ggccatagcc atcggtaaaa cgatttggca ggtaaactcg gcactcagca ccaagttgtt
    25981 ccaaactttc cttcacaata gaagccgaag tcatgccatc cgcatcgtag tctccataaa
    26041 cgagaatatt ttccctttct tcaatagcct gacgaatccg ctccactgcc ttgtccatat
    26101 catggagcag ataagcatca tgtaagtcct ccaaggaagg ttctaaaaac ttcttcagac
    26161 tttcttggtc ctgaatccct ctctcaaaca ataaccgagc cacctcagga cccagtccag
    26221 ccttcttggc tatctttgta aaatccgcat cttctacctg cagggcaaac tgccattcat
    26281 aagtaggtgt tatcaaaaag acatccactc tttctaagaa ttctattgct tcattataac
    26341 atgatttaga cgttttctct atccagattg cttttttata acattttata gtatattgaa
    26401 actagaatag tacacctcta cttctaaaat attgttagaa atcgatttga ctgtcccgat
    26461 cgatttttcc tgttcttatt tcactatagt gaattttttc agatacgatt tgacaagaac
    26521 attcttttat tgcagaatcg tgttataaaa tctaacataa aggagttctc tcatggcttt
    26581 agtagaattt aaaaacgtcg aaaaatatta cggagactac cacgcactcc gcaacatcaa
    26641 tctccgtttt gaaaaaggac aagttgttgt cctgcttgga ccttctggct ctgggaagtc
    26701 cactcttatc cgtacgatca atggtttaga ggctgttgac aaaggaagtc tcctagtcaa
    26761 tgggcaccaa gttgctggtg ccagccagaa agatttggta cctcttcgca aggaagtcgg
    26821 catggttttt caacatttta acctttatcc acacaaaaca gtgttagaaa acgtgacact
    26881 tgcacctatt aaagttctag gaattgataa aaaagaagct gaaaaaaccg ccaaaaaata
    26941 tctggaattt gtaaatatgt gggacaagaa agattcctat cccgccatgc tatctggtgg
    27001 acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg catccggaac tcctcctctt
    27061 tgatgaacca acatctgctc ttgatcctga gactatcgga gatgttctag cagttatgca
    27121 gaaactggcg cgtgatggga tgaacatgat catcgttacc cacgaaatgg gctttgctcg
    27181 agaggttgcg gaccgcatta tctttatggc cgacggagaa gttttagtag atacgacaga
    27241 tgtcgataac ttttttgaca atccaagcga acctcgtgcc caacaattcc tcagcaaaat
    27301 tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc tatgaaaaaa aattcttttt
    27361 atcagcatta ttgattagcc ttttcggcct tgctgctgcc aaaccagtcc aggctgatac
    27421 aagtatcgca gacattcaaa aaagaggcga actggttgtc ggtgtcaaac aagacgttcc
    27481 caattttggt tacaaagatc ccaagaccgg tacttattct ggtatcgaaa ccgacttggc
    27541 caagatggta gctgatgaac tcaaggtcaa gattcgctat gtgccggtta cagcacaaac
    27601 ccgcggcccc cttctagaca atgaacaggt cgatatggat atcgcgacct ttaccatcac
    27661 ggacgaacgc aaaaaactct acaactttac cagtccctac tacacagacg cttctggatt
    27721 tttggtcaat aaatctgcca aaatcaaaaa gattgaggac ctaaacagca aaaccatcgg
    27781 agtcgcccaa ggctccatca cccaatgcct gattactgaa ctgggcaaaa agaaaggtct
    27841 aacctttaaa tttgtcgaac ttggttccta cccagaattg attacttccc ttcacgctca
    27901 tcgtatcgat gccttttccg ttgaccgctc tattctgtct ggctacacta gtaaacgcac
    27961 agaactacta gatgatagtt tcaagccatc tgactacggt attgttacca agaaatcaaa
    28021 tacagagctc aacgactatc ttgataactt ggttactaaa tggagcaagg atggtagttt
    28081 gcagaaactt tatgaccgtt acaagctcaa accatctagc catactgcag attaaggagg
    28141 acaccccatg acagatttat catcttggac agcctatttt caggattttg gacaattttt
    28201 caatggtttc ctctttactc ttgccctagc gattggatcc tttatcctcg ccatggtctt
    28261 aggaatcttc tttggtgcca tgtcaaccag taaacgtcca attttacgca ttttagctca
    28321 catctttgtg gaattttacc aaaacactcc cctcttggtg cagtttgtta ttgtttttta
    28381 tggcctacct cttatcagtg accatactat catgattcca atttattgga cagctgttct
    28441 ctgcgtggga ctctatcacg gcgcttatat cgctgaggtt attcgttcag ggattcagtc
    28501 tattcctagt ggtcagatgg aggccgcctt gtcgcaaggt tttacctata tcagtgccat
    28561 gcgcttgatt accttgcctc aggccttccg catcattctc cctccattga ccaaccaaat
    28621 tgttaacctc atcaagaaca catctactgt agctatcatc tctggagtag acttgatgtt
    28681 tgtgactaag tcttggtcgg ctctcaacgg aaactatatc ccagcctttt taggtgctgc
    28741 tcttctctac tttgccctat gcttccctgt tgcccagttt ggtcgcaaga tggagcaagc
    28801 caataaaaaa gcctattcac tttaggaggt tactatggaa tctattttag aaattttaac
    28861 cccagataac ctagtcttta tctttaaagg atttggcttg accctctata tttctctgat
    28921 tgccatcatc ctctctacta tcatcggtac cgtgcttgcc gtcatgcgaa atggaaaaaa
    28981 tcctatctta cgcattattt ccagtattta tatcgagttt gtgcacaacg ttcccaacct
    29041 tctctggatt tttactatct ttttggtgtt caaaatgaag tccacaccag caggtattac
    29101 agcctttact ctctttacat cagcagcctt ggctgagatt attcgaggcg gtctcaatgc
    29161 cgtagacaag ggacaataca aagcaggaat gtcacaaggc ttcacctcag cccaaatcct
    29221 ctactacatc attctcccac aagccagccg caaaatgcta ccagccatca tttctcagtt
    29281 tgttaccgtg attaaggata ccagtctcct ctactctgtt atcgccctac aagaactctt
    29341 tggagccagc caaattctca tgggccgtta tttcgaacca gagcaggtct tcagtcttta
    29401 catcctgatt gccctcatct acttcagctt taacctagca atttctagcc tgtctcatat
    29461 gctagccaaa cgttggcaac aagctgcaga ataatactct tcgaaaatct cttcaaacca
    29521 cgttagctct atctgcaacc tcaaaacggt gttttgagca gcctgcggct agcttcctag
    29581 tttgctcttt gattttcatt gagtataaac agccactctc cagttcaatt ggagagtttt
    29641 ttgatgagag tagatattta tagacctcaa tttgacacca tacattttct atgataaaat
    29701 gtaacaaatt tatttacaac aaatcgaaat ctaaatgaaa tggaattttc tatgaaatca
    29761 gtcaaaggac tactctttat catagctagt tttatcttga ctcttttgac ttggatgaac
    29821 acttctcccc aattcatgat tccaggacta gctttaacaa gcctatctct gacttttatc
    29881 ctagccactc gtctcccact actagaaagc tggtttcacg gtttggagaa ggtctacacc
    29941 gtccacaaat tcacagcctt tctctccatc atcctactaa tctttcataa ctttagtatg
    30001 ggcggtttgt ggggctctcg cttagctgct cagtttggca atcttgccat ctatatcttt
    30061 gccagcatca tccttgtcgc ctatttaggc aaatacatcc aatacgaagc ttggcgatgg
    30121 attcaccgcc tggtttacct agcctatatt ttaggactct ttcacatcta catgataatg
    30181 ggcaatcgtc tccttacatt taatcttcta agttttcttg ttggtagcta tgccctttta
    30241 ggcttactag ctggttttta tatcattttt ctatatcaaa agatttcctt cccctatcta
    30301 gggaaaatta cccatctcaa acgcttaaat cacgatacta gagaaattca aatccatctt
    30361 agcagacctt tcaactatca atcaggacaa tttgcctttc taaagatttt ccaagaaggc
    30421 tttgaaagtg ctccacatcc cttttctatc tcaggaggtc atggtcaaac tctttacttt
    30481 actgttaaaa attcaggcga ccataccaag aatatctatg ataatcttca agccggcagc
    30541 aaagtaaccc tagacagagc ttacggacac atgatcatag aagaaggacg agaaaatcag
    30601 gtttggattg ctggaggtat tgggatcacc cccttcatct cttacatccg tgaacatcct
    30661 attttagata aacgggttca cttctactat agcttccgtg gagaagaaaa tgcagtctac
    30721 cttgatttac tccgtgacta tgctcagaaa aatcctaatt ttgaactcca tctaatcgac
    30781 agtacaaaag acggctatct taattttgaa caaaaagaag tgcccgaaca tgcaaccgtc
    30841 tatatgtgtg gtcctatttc tatgatgaag gcacttgcca aacagattaa gaaacaaaat
    30901 ccaaaaacgg agcttattta cgaaggattc aagttcaaat aagtaatcat actctcctgg
    30961 aatttcccag gagagttttt tatagccaaa tgaaataaga ccggaacgat ggaattttgg
    31021 cattcaaatc aattgataag aatattttat agtggagtga aataggatac gaacaaattg
    31081 attaggaaaa tcaaatgaat ttatagaaat cttttagcag ttatgttatc ctattctagt
    31141 ttcaaaacgc tatagaagca gcattgtgct agtctagatt cagtttacta tactaaaacg
    31201 agtagcttga aatcaaaaaa cccaccctca caggcaggtt ttatctgtat tattcagcta
    31261 gattatgctt taccttctga accgaatacg tcgatacgtt cttcaaccga tgcttggata
    31321 gcttttacac cgtcagccaa gaatttacgt gggtcgaaga gttttttctt atcgtattct
    31381 gcttcgtttg cttcgtagtc acgagcaaat ttacgagttg cgttagcgaa tgcgatttgg
    31441 cattctgtgt taacgttaac tttggcaaca ccaagtttga tagctgcttg gatttgctca
    31501 tcaggaatac ctgatccacc gtgcaatacg attgggaatc ctggaagagc ttctgtcaat
    31561 ttttgcaagt ggtcaaggtc aagaccttcc cagtttactg ggtaagggcc gtggatgtta
    31621 ccgataccag ctgccaagaa gtcgatacca gtttcaacca ttgctttagc gtcttcgatt
    31681 ggagccaatt cacctttacc gatgattccg tcttcttcac caccgatagt accaacttca
    31741 gcttctactg agataccttt agcgtgtgct ttttcaacaa cttctttagc caatttaagg
    31801 ttttcttcaa ctggaaggtg tgaaccgtca aacatgattg aagtataacc aacttcgata
    31861 cactcaagtg catcttcgta gtgaccgtgg tcaaggtgga tagctactgg tacagtgata
    31921 cccattgatt caacaaggtt agcgatcaag ttgcgagcaa ctttgtaacc acccatgtat
    31981 ttagcagcac ccattgaagt ttggatcaaa actggagctt ttttagcttc tgctgcgcgc
    32041 aagatagctt gagtccactc aaggttgttt gtgttaaatc caccaactgc ataaccgttg
    32101 tcacgggctg cttggacaaa tttttctgct gaaacgattg ccattttatc aggcctcctg
    32161 tatattttta tgggtcatcc catttacatt gttcatttta tcactttttg ccaaaaaaat
    32221 ctagtttttc ccgcagtttc aattgatttt cttctaactc catctatgta aaccctttct
    32281 ctccctagtc ttgggcgact tttggaaaat ctataaagaa ggttaaacga ttctcctcca
    32341 tctcgaaacg ataagctaat ttttcatgtt ctaatagact cttaaccaca aagagcccca
    32401 taccagaccc cttgaccttg cgactagcat tgtcagaaaa agactgggct agtttttctt
    32461 gttcctctga gctacagcta ttttcgataa aaagttctcc ttctctttct ccaattcgaa
    32521 ctaagccacc tggaacagag tgcttaatgg cattgctgat gagattagaa agaatcaact
    32581 tcataactga tgggtttaga taagcctgct gatgggtcaa actattgtct atctggagct
    32641 ctctttcctt ggctagcaag gcataatctt tgaccagatt ttgcgtcatc tggaggaggt
    32701 caattgtttc cctatcatct cgcaattcct gcacagaaga gagggaaagt atctgcagaa
    32761 catggtgatt gagttcatcc acaatcccca aggcaactcc cagatactgg tctctatcct
    32821 tataacgacc gatattctct ctcatatttt cgattaggat tttcaaacta gccagcggtg
    32881 ttttcaattc atgagaagct cctcgtagga attcgacctt catcttctcc agctggagaa
    32941 tggcttcatt cttttcatgc aagtccgcaa taacagtcaa gagatgctgg tagaggctat
    33001 tgatttgttc cttgagatta cctatctcat ccttagaatc cacgcgcaat cgcacttggg
    33061 catccaggta catcatccga cgagtcaccc gcttgatttc caaaatcggt gcaacaatag
    33121 tccgagcgta gatgtaggcc accaagaggg aaatcagaaa ggaggccagc aaggtatagg
    33181 gaagaaactg gagactgatt tgctccgctt ccttttgtaa atccatggaa gctagaaact
    33241 ggagaatcat agtaccaccg tcttgcgttt tcacctcgcg ctcctcaata aagagagagg
    33301 ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac ttctaacttg tcctcggtca
    33361 tctcaccttt gacggtcccc ttgatatcac tagtctggga atacaagtct aacacttgct
    33421 cgatactctg cctatctttc ccttctaggg actgggcaat ggctgttgcc ttttgaccaa
    33481 tggtttcctg acgatgactc agataagtcg aaggaaaaag aaaataaata gctaaatgaa
    33541 ggcagataac cagaacacta aatatcgaga aggtatagat aaatatcttt gcaaataaac
    33601 ctgttcgttt cattttcgct ccaatttata accaacattg cgcacagtga ggatacaatc
    33661 caagtctagc tttttccgca attccttgat ataaacatca ataacacggt caaagggaac
    33721 ctcatctgtc gctttccaga cggcatcgat aatctgagat cgagtcaagg cccggccttc
    33781 atttttcact agatagtcca gaatttccaa ctctttggca ttgataggca cttcttgacc
    33841 tgcgatgctt gcactgtagc tttcaaagtc caccttggta tccttgtaag aaaagattcg
    33901 tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc acttttaaaa gggagaggga
    33961 gaaaggtttt tccagatagc catctgccaa agaggcaaag gcactcatct tgtattcctc
    34021 atcctgaaaa gctgtcaaca tcaagacagg aacctgactg gttttacgaa tctcagctag
    34081 gacttctaag ccgttgagct tgggcatctg gatatccagt aaaaccaggg ccacctcata
    34141 gctagaaaat tgctccagag cttcctgacc gtccgctgcc tcaatagttt catagccaca
    34201 atccgtcaaa taatcactga ccccctcacg gatcatctct tcatcttcta caattaaaat
    34261 tttcatactt taactgctct ctatttttta tttttcttag aataaatacc tactctattt
    34321 tctattatag tctcttgctg gccttttgtc tgcaagcaac tgaccactag ataaaacgtt
    34381 gtgaaattcc tttctcataa attcaataac tttagtatat tatatttaag cactaaagta
    34441 caaagaaagc aactgaaagc aatgattttc accactgctt tcggatttat tttgaattgt
    34501 taaatagcca ttcctatcca ctattcttga atagaaacac aagatgcaat ctttattcta
    34561 gactcatttt ttcaaattta ttcaccatcc agcaagagct cttttggttg ttttctaagg
    34621 agattgcttg aagcaagcgc cataacgaga accactagaa ccaaggcaag gacaaaaatg
    34681 atgataaagt ctgatgtctg aatggaaatg tctaggctcg acaaggtctt gctaaagcca
    34741 tctacttctg caccaccacc aaggttagag gcttgagccg ccttactagc ctgtttggca
    34801 acacctgaag tcacattggc aaggacagtg tttccaattg cacgggcagt gtaattagct
    34861 aggaagtaag cagaaactag agcagggata gcaatcaaga tagattcggt gatgaattga
    34921 cccaagatac ttgcctgctt gaggccgata gagaggagaa ttcccacttc cttgcgacgg
    34981 gcgttgatcc aaaggctgag caagagggca aggaggagaa ctgagaagct caagctaccc
    35041 cagaagagga ggttggccat cttgtacata ccagagatag attgctcaag agctgggtag
    35101 ttagaggagc tcttgacgag tgtgtagctc ttccagttga taccactgat gccattcaac
    35161 tctttcataa catcatccaa gttcttgtct gctgttacaa agaaggttgc gtccccataa
    35221 atggctgtgt cttctgtgta tccataaagt tttgcagcag tgtgaatgtc tgtaatagct
    35281 gtgttttcgt aaagttcttg tgagtaggtt actgctgact tattatgacc atcaaagagt
    35341 cccttgattg tcacttcaac tgtttccttg gctccttttt cattatctgc atcgtagata
    35401 ttagagtcca gtttaacctt gtcccctact ttccagccgt gtttggctgc caagtccttg
    35461 tgcaatagga ttttatcctt gtcgtcgttg gttaagtgct ctccttcgac tagtttataa
    35521 gaaccagaga caaacttgtc ttctttagag gagtcattga cacctgtaat catcaagcta
    35581 cttccaaaac gcttggcacg atcagcagtg agattcttct tggtttctgg cgtttcaatc
    35641 aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt tgacataaga ctcaatggcc
    35701 ttgttttcgg tgattttttt gatgtcttca cccttgatat tcccagcacc acgaggcgtt
    35761 ccttggttga cgcgacgatt gatttgcatg gagaagctat tggtgatatt tttaaaggtc
    35821 tcctgagaag ccttggcagt agctcccttg attgacaagc cgaccaaact caagctcgcc
    35881 atgaggagaa taatcaggaa gatgacaatc gatttgaaaa acttccttgt aacataggca
    35941 aatgcgttgt gtaacataga ttccctttct agattttgtt ttaatcattc tattaaaata
    36001 agctcaaatt atttactagt attgcgcgtt tcagtcagtt tcttatcctt taattcaagt
    36061 gtaatatctg acgcttgtgc cacttcttta ctgtgagtta cgacaatcac acatttacct
    36121 gttttctggg caagtgattt gagtagttcg acaatatctc cagcagtttt aggatccaga
    36181 tttcctgttg gctcatcagc tagaataact ggagcttctg agaccaaact gcgagcaatg
    36241 gcaacacgtt gctgttgacc acctgataac tggagaacat tccgcttgat ctggctttca
    36301 tccaaaccaa gctcaagaag tgtattcttg cttgcctttt tgttgaccaa tcggatattt
    36361 tccagcggag aaagataatc tatcaagtta taattttgaa agaccaggga aatatggtgc
    36421 atgcgatggt aagaatagcc cttcttacga atatcctctc cttgaaaaag gatagaacct
    36481 tcaacaggac tatctagacc agcaagtagg gacaagagtg tggattttcc tgctcctgac
    36541 tccccaataa tactgtaaaa ttttccgggt tcaaaattat aattgatctg atataggact
    36601 gcttcagcag tattcttata acggtaggta acatcttgta attgtaataa agtcatgatt
    36661 tctccttctt aactaataga tgataaaatt tctttcggtg attttctaaa taagaatagg
    36721 aaacaaaggg ctacagataa gcaactaagc agaactagaa aaacatagga ttctgcaaaa
    36781 gataagatgc tagttgataa actgcttgct ttggctagtg tatcttgtaa gcttgcctga
    36841 tctccacttg ctagtagagt ttggagtagg taagttgtga ttgcgtttcc tgcaacaaat
    36901 gctggaagca aagctccaag agataccaaa actacctcta aacagaattg taggaagatc
    36961 gagctcttgc cttttccaag tgcaagtaaa atccccactt catagacccg ttctctcaac
    37021 cagagagaca aaaccagaat taaggctcca gctcctgcta tcaacatccc ataaaggaag
    37081 atggtcagga aggtttggaa agttgcaact gagtctttga tttgttcaaa agccttgttt
    37141 tccttttcga cttggtagcc ttgattttcc aaggccaagt tttctacctg cttcatgagt
    37201 ccgtccattt ccttaggatt ttctacatag aagcgtgctg cactgacttg agcttcacta
    37261 ttgcccaaaa gggtttggct actttcatag tctgtaaaga cttgattttc actgaagtca
    37321 gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa agatgccgat aatctcaaac
    37381 tctactgttt gtccttttcc agattcagac tgaccagcat ccaagccaat cttgtcatga
    37441 agtgaaagac cgttcttctt agccaattct tcgtggataa ggattttctt ggaatcccct
    37501 ttttgaaggt gtcgcccttc ttttagattg aaagccgaac tggtaaaggt tacatccttg
    37561 gatgaatcct caagagccgt taagctaacc aagttattgt ctgcagctga taaatcatca
    37621 cgctccacgc tctgctcgcc agtcactgct tccttgtctt ttagttttgc gaccgtctca
    37681 agttcaggag agacattttc cagcccctta atcttgctta cagatgctag gtctgacaac
    37741 ttgaatgtct gaccattctc tatcttctta atagaaaaag atgtattgag tgatttataa
    37801 agattgcttt ctactgtttt gttggacttc atcagagtca aacaggctga aattccggcc
    37861 aataagacca ataaaatcag aaataaaata aaacttctca gtcgctttct gctgacataa
    37921 gcccaagatc tttggattgg attcatttgt cacctccata tttgtaagac tattataaaa
    37981 cccaaatatg aaatgtttat gaaatacgaa aaaaaaatat cgagtagggg ataatctcta
    38041 gcccctctca taccaccgta cgtgccgttc ggcatacggc ggttcaacta acttttaacg
    38101 catgtcgttc aaggtaataa tccaaacacg aaaccagtcc acgtttttca agggctggtt
    38161 ttgatatagc acgtttaagt accgacttct gagctactaa ttgatagtgg tcgccccagc
    38221 cagatacctt atctgctatc catttaggaa cccctaactt aagcaatccc cataatcgtc
    38281 tcgatttctt cttccattgc ttccagataa tcactcgtag gcgagtacgc aagcgctcat
    38341 ctatgctagt gactatactt ttcatattta taattcattc ctttcgtttc actcaaggca
    38401 caacacagaa tgaaaaagtg ttgtgatctt tattttgttt tataataata gtgagaaagc
    38461 ctatcactac tacaaatcac ggggaggtga ataagtgagt ggtacagcca ctacctcgca
    38521 tattttgtca catcatttaa cggtacataa taagttgtac catctgaata agttgctaca
    38581 atatcatttg catgctctcc ttcaccttta gcaaaggttg gagctcctgc tggatgattt
    38641 ttatttgcct ctttcaattt ttcaataatg tcattttttt ctgtatcttt tatattatca
    38701 ggatttttca ctaagatttt gtctggatat gtcggtttag cagaaacaat ttttactgtt
    38761 atttcttttt tattcgaagc acttgtccag tttccagcat tatctttagc atttaatttt
    38821 acagtaattc ctgaactagg aacttcagta gcaggttgat tatcaacatt attcaacttt
    38881 aatttcaaaa gagctgttgc atcagacatt ttatcaatcg ttatatataa tgatgaattg
    38941 ttattataac cagtttcttc atatttagct gtttgtgagc tacttgaaac agaactgaaa
    39001 ttatacccac tacctccctg attatcttca atgcttacgt ctaaatgaac ttccccacta
    39061 ttatttggct tagcaacaac tgttatagta aaataacata aaatttgcat aaatagatta
    39121 gggaaatcaa agcaacttct aggaatgttt tagcagtcac agtgtacttt cccagcatca
    39181 agccactata actctgcaca taaaaatgga gaagatggca atcctcttct ccaaatatta
    39241 acttctttac aaaccaacta tagttgacaa agaacctaaa atcaattgat aacacaaggt
    39301 caggtcggtc aactctttca actgaagccc tgtcaactct tcccatttat caatcttgta
    39361 ttggagagaa ttgcggtgca gatagagttg ctgggctgtt ttagtgagaa cagcactatt
    39421 ttcccaaaga gagagaatga tttcctgaat ctgatcttga tccaaaatca tctggtgtag
    39481 acattcttta attggcttca agtccacgag tctttctccc atactccaaa gatagagctg
    39541 agaaaaagta tgaacacctt ggtgaccctg acgccaccat gtcttgaaca aatcccgctc
    39601 agctttgatt aagtctgata gggcttgatg tcctgtctga gaccaaacct gacccaacat
    39661 gatagaaaga cgaagtccaa agtcatactc aaccgcttca atcgtatcac ttaaaatatc
    39721 tcttacagaa gtgtatttgt tttgttgaag cacgaaaaca taatcctgag ctccgacctg
    39781 tagcactgtc tgacaattcg gaaaaagagt ccgcatcata tctagccaag aagccagatt
    39841 ttcctgctga aaataagaaa gatggcaata aaccaactga atctttttaa aaacttgcgg
    39901 tgcctgtccc ttgccttcaa ccagatagga ataccaaggg tttagcgaac gagcctgctc
    39961 ctgctgggtc aaaagggcaa ccaactgctt ttcacgctcg ctgagcccag cttcctccag
    40021 caaaatccac tgctgagaag ctaaagggag cgtgagatag ccctctttct ctactggttg
    40081 gtctgaaatc cgagcctcag gaaaccagtc ttgtagttct ttttccctca tgttctagcc
    40141 ctccactttt tggatgcacc atgaaaccaa actctcaaga cgttccagat tctcagtcat
    40201 atggagatag cccataaccg cttcaaatcc cgtggacata cgataagtca cgacatctgc
    40261 atttttagcc tttgtgtggc tattggtatt gcggccacgt ttgtagattt cttcttcttt
    40321 ttccgttagg acctgctcct ccaacatgag agcaatcagg cgagcctgag ccttggctga
    40381 cacatacttg gttgcttctt gatggagttt attgggtttg gtcatacctt tgaggatgag
    40441 gtgacggcga atatacatag aatacaccgc atccccctca aaggctagcg caatcccgtt
    40501 aatgagattg acatcaatca cgtgtccacc tcactccatc cttggtatca aggagcttaa
    40561 ttccttgagt aaccaattgg tcacggattt ggtctgctgt cgcaaagtca cgattagcac
    40621 gcgcctcttg gcgtttttga atcaagtctt caatctctgc atccaaaact tcctcaacaa
    40681 agacaattcc aaaaatttct aacatatctg caagagcttg cttgacactt gcatcatagt
    40741 tccctgagtt gatccatttg gccatttcaa agacaactgt gataccgttg gcagcattaa
    40801 aatcttcatc catagctgct acaaacttat ctttaaagtt ttgtaactct tgggcatcca
    40861 cgtttcctgt aaatggttgt tcgtaagtat tcttcagata cttgagattg gtctcggcat
    40921 cgcgaactgc cttttccgtg aagttgatag gcttacggta gtgctgggtc gcaaagaaga
    40981 aacgaagtac ttgcccatca agagttttaa gggcatcgtg taccgtaatg aagttaccca
    41041 aggacttaga cattttgaca ttgtcgatat tgacaaagcc attgtgcatc cagtagttag
    41101 caaaagcctt gcctgtttta gcttcagatt gggcaatttc attggtgtgg tgtggaaact
    41161 ctaggtcagc tccaccaccg tggatatcaa tggtatcacc taaaatctct gtcgacatga
    41221 ctgaacactc aatatgccaa cccggacgtc caggtcccca aggactatcc caagaaatct
    41281 cacctggttt ggaagatttc catagagcaa agtctacagg attttcctta cgagccgttt
    41341 cttcatcggt acgacctgaa gcacctagct ccaaatcttc caaggtttta ttagccaatt
    41401 tagcatagtt gtgggatttt tctacacgga aatagacatc cccttgactc tcataggcaa
    41461 agcctttctc gatcaagtct tccacaaaac ggatgatgtc tgccataaac tccactacac
    41521 gcggatggcg agtcgcaggt ttcacgccca aggccgtcac atcctcacga aaggcagcga
    41581 tgtacttatc cgcaacctcc tgaggcgtga tgccttcttc cctggcacgg ttgataatct
    41641 tatcatccac atctgtaaaa ttggaaatat aggcaacctt atacccacgg tactcaaaat
    41701 agcgacgaat cgtatcaaaa gctaccgtcg aacgggcgtt tcccacgtgg atatagttgt
    41761 acaccgttgg cccacaaaca tacatcttga tcttgccgtc ctcaatcggg acaaattttc
    41821 gcaaatcacg agacatggtg tcatagattt taatcataaa tcataatcag gaaagctgaa
    41881 atccaagaac aattagtttc atcactaaaa gttcaagtaa atttcagtcc gaatatctct
    41941 acacttcgga atcccttgct cctttctcat tcagataaac cacctgagtc tgtttgacaa
    42001 agccaatttt ttcatacaaa cgtttggcac ctacattgct atcttccact gcaatctgaa
    42061 attccttgtc attttgctca attagttggt tgacgaggga ttttgctaag tagcttccat
    42121 agcctttccc acgttcaggt tccgatattg ctaaaccgta gaggtaattc gtattagtcg
    42181 ataaatcaac cgtacaagtt ccaataacct gaccagcttt taataaaata tatagtcggc
    42241 tttctggatc tttcagagct tcagcgacat atctatccac aacttctctc gattcatgtt
    42301 cctctgaaaa tgcctgaaat tttaattgac taatttgatc ctgatacgaa ctatctgcta
    42361 acaaaatttc aagatgggaa acatttgcta acggataagg tcttctatcc ttacctaacc
    42421 aagtttctgt ctcttcatcc tcgattagtc cccagttact ggcaaagtca ggatgattct
    42481 ctaaaaaaat acgttctgtc tgaaaagtga ctgaccgaat ggggaaagaa gctgtttctc
    42541 tctcaaaact agtaaacaat gcacgcgcaa tcccctgacg gcgatgacct ggatgaacca
    42601 gtatcgtcac ttctacatct tggtcatctg catagacagt taataaacca acaagttcgc
    42661 ctttttcata ataaaggaaa aaggcgggca tgtttgggtc aaaattaagc atgttagaga
    42721 gatagggatc gcgataggta ccgtcatagt tttggcaaca gttaattact tttttcgcct
    42781 cagatagctc ctcttggctt aacttgtttc ttgcttgaat catataggta tcctctacaa
    42841 accagacgat ctgtgactgg catctttagc ctgctcgagt ttattgacat aatactctcg
    42901 tttttcttcg acttcgtgaa tgacaggctc atctttctta ccatgaagac ggacaatctt
    42961 ggccggaata ccgacaaccg tcacgtcact aggtacatct gctacgacaa ctgctgcagc
    43021 accgaccttg gcattctcac caatttccac aggcccgata acttgggcat gggctgatat
    43081 gagggctccc tttcgtacag tcggatggcg tttgccacag tctttccctg ttcccccgag
    43141 agtcactccg tgatagagaa gaacgccttt ttcaacaatc gctgtctctc caatcaccag
    43201 accagaacca tggtcaataa aaacacctga atcaatctgg gctcctggat gaatctcaat
    43261 ctgagtccaa aagcgccaaa actgactgta catacgagct aatagtttga agccgtgctt
    43321 ccagagaaaa tgcgagagac ggtgggccgc caaggccttg acacctggat aagtcagcaa
    43381 aacctccaaa gtggtgcggg ccgctggatc attttctttt acaatatcaa tggtttcgcg
    43441 ccaccacccc atacatttct ccttttctta ttctgaatct tttggtgttt ctgtaaattc
    43501 tttcttaggt ttgtgatcct tgtgatgacg tgggcggtga gggcgctcag acttttcacc
    43561 tttttcatca tgctcaggtt ttggcggacg aggtagaaga gccttcatag aggcatcgat
    43621 acggcctttt tcatcaatct tgataacctt aacatcaact tcatccccga tttctaccaa
    43681 attctctaca cgattggtac gagtccaagc catctcagag atatgaacaa gggcatctgt
    43741 cttatcaaag aggttaacaa aggcaccaaa tttctcgata cgaacgactt tagcacggta
    43801 aacttcatcc actttggctt cacgaaccaa accagcaata atttctttgg cacggttaat
    43861 agcatcttgg tcactagagt agatagacac atttccttct tcgtctatat caatcttaac
    43921 acctgtttca gcgataatct tgtcgatggt ttctccaccc ttaccgatga caatcttaat
    43981 cttgtccaca tcaatcttga tcgtatcaat tttcggagca gttggagcca attctggacg
    44041 aacttctgga atggttgctt caatgacatc aaggatttca aaacgcgctt tcttggcttg
    44101 agcaagagcc tccgtcaaga tttctgcagt aatcccttga atcttgatat ccatttgaag
    44161 ggctgtaatc ccatcacgag tacctgcaac cttgaagtcc atatctccaa agtgatcttc
    44221 caaaccttgg atatctgtca atactgtgta gttatttcca tctgagataa gtcccatagc
    44281 aataccagct actggcgcct tgattggcac accaccagcc ataagggcaa gagttcccgc
    44341 acagatagaa gcttgagatg aagaaccgtt tgattccaaa acttctgcta ctagacggat
    44401 agcgtatggg aattcttcca agcttggcaa gacttgagca agagcacgct caccaagggc
    44461 accgtgaccg atttcacgac gacctggcgc accgtaacga cctgtttccc ctacagaata
    44521 ttgagggaag ttatagtggt gcataaagcg tttcttgtac tctggatcca aaccatcaat
    44581 gatttgagtt tctcccatcg gagccaaggt caagactgaa agagcttgag tttgcccacg
    44641 agtaaagaga cctgaaccat gtacacgagg aaggaagtcg acaaccgcat ccaaaggacg
    44701 gatttcatcg accttacgac catcaggacg caccttgtct tctgtaatta aacgtcgcac
    44761 ttctgcgtgt tccatttgtt ccaagatttc agccacatca cgcataatac ggtcaaattc
    44821 ttcgtggtcc gcatattttt cttcgtaaac ggcagtcact tggtctttca ctacttgagt
    44881 cgcagcttca cgggccaatt tctcttctac ttgaactgcc ttttggaggt cactgttgta
    44941 ggctgcaatg atttcagctt gcaattcagc atccacgtga agcaattcca cttctgcttt
    45001 ttctttaccg acagcagcaa cgatttcttc ttggaaggca atcaattctt tgacagcttc
    45061 gtgcccttta aggagcgctt ccaacatgat ttcttctgac aattctttgg caccagactc
    45121 taccatgttg atagcgtgct tggttccagc tactgtcaat tcaagaagag attgctctgc
    45181 ttgttcttga cttgggttga tgatgatttg gccatctaca tatcccactt gtaccccagc
    45241 aattggtccg tcaaatggaa tatctgaaat agacagtgcc aaagatgaac caaacatagc
    45301 agccattggt gcagatgcat tttcatcata agaaagcact gtattgatga cttggacttc
    45361 attacggaaa ccttccgcaa acataggacg aatcggacgg tcaatcaaac gcgctgtcaa
    45421 ggtcgcatct gttgaaggac gtccttcacg tttcataaag ccaccaggaa acttcccagc
    45481 cgcatacatt ttttcttcgt agttgacttg gagtgggaag aaatccccag ttgccatttt
    45541 cttagacata acggcagcag tcaagacagt tgactcaccg taacgtacga caacagatcc
    45601 atttgcttgc ttagcaacct gaccagtctc tacaattaac tcacgacccg caaaagtcgt
    45661 ttgaaacact tgttttgcca ttttaatccc ctttggattg atgaaattat acgccttgcc
    45721 tacaaagatc aagataccaa ggacgtcaaa agcaaagtaa aaataggaaa ctgacgaagt
    45781 cttcgatgaa gacaagacag tttatctttt ttacacagct tttcggccgt gttcaattac
    45841 acaagatatt ttggacggtt cggcttgccg aacatttctg tagaaaaata ggaaggtgac
    45901 gtcgcactcg acgagtgcta ggaagcttat cttttttcct aagaaatgag accaaaattc
    45961 aagtcatcaa gataccaagc cgtcaagcaa ctcaaaggaa gataggaaat cgaacgacgg
    46021 agcgactgct cctagggaga tttatctttt tccacagagt tgtaggcaag ttcagttttc
    46081 aagatacatc attagaaagg tttaatacta aagtatctaa agctttcacg ctaatcgcta
    46141 tcgggcgatt agctaaatgc tttactaact ctctcgtcaa ataacatcga tttgactcac
    46201 tcgtgtcgtt aaatcttaca gtttaaatgc attgtattat ttaatacctt catctttgta
    46261 tcaagtacgt acagaattta ttttatcata tttttcttaa aaagtgaggt ctttaccatt
    46321 aaaaaggaac cattcccctc acctgagaag aatggtttgc ttttattatc ctagagactg
    46381 gtgattaaac aaggcatggg ttgcttgatg gatgtatttt gctgtatcag cattattcat
    46441 cgtatagaga tgcacaccgg caacatcctg agttaccaag tccacgattt ggtccactgc
    46501 ataggcaagt cctgctgctc tgagcgactc agggtcatgc tcatacttgt ctaagatggc
    46561 tttaaatttg cgtggaagat ggatattctc acaagtcttc aagagtcgga gagcctgatt
    46621 tcgattcaga attggcataa ttcctgcatg aatgggaaca tcaatcccag ccaagataca
    46681 cttgtcctga aaatcataga agcgctcatt gtcaaagaag agctgagtta cgaggctcga
    46741 acagcctgca tccactttct tcttaagatt ttgaatatct gaaatctgat ttggcgaatc
    46801 tggatgccct tctggatagc aagctccaat aatatcaaag tgaggggctt gttccttgat
    46861 aaactcaatc aagtcggttg catagcggaa atccttttgt ggttctacgt ctggaataat
    46921 atccccacga agagccaaga ttttctgaac cccaactttg tccaagtcaa caatagtttc
    46981 agcaaccttg tccttagtta gataaatagc tggcaagtgg gcaatggtcg gaatcgccaa
    47041 gtcattttgg ataaagtcag ccaaacgaac cgtcgtttcc ttgatattaa atttattatt
    47101 gctggcagtt acactgataa aatggggagc caactcctgc atatcctgca aggctgaaat
    47161 aatgttacca ttacccacgg ctgggtttgg agggaacact tcaaatgaga gtgacggtgt
    47221 ttggcgtgac atatgtaata accttttcta gttgatttct ttttgaacaa ccactgtatg
    47281 gagagaaatc caatcttaca atttctcacg cgcagcttta gctgcttcaa caaggcggat
    47341 caagctttct tttgtttctg ggataccacg tgttttcaaa ccacagtcag ggttgatcca
    47401 aactttcttg cttggcactt tagcaaggat ggcttcgatt gtgttgtcga tttcgccttc
    47461 atttggtaca cgaggtgagt ggatatcgta aaccccaggt cccacttctg tttggaagtt
    47521 tttcgctttg agttcgtcca agatttcaag gtttgaacgg ctagcttcaa aggaaataac
    47581 gtctgcatcc atgttatcga tagctgggat gatatctgta aattctgagt aacacatgtg
    47641 agtgtggatt tgtgtgtctg gcgctactgt tgagtgtacc aagcggaagg caggaatagc
    47701 ccagtcaagg tagtcttcgt accagtcgct acggcggagt ggcaattttt cacgaagagc
    47761 agcctcgtcg atttggatga ttttcacacc agcagcttca aggtcaagta cttcatcctt
    47821 gatagcaagg gcgatttgga gagttgaatt cttgatagag atgtcttcac gtgggaatga
    47881 ccagttaagg atggtaacag gtccagtcaa cataccttta acaggtttgt ttgtacgact
    47941 ttgtgcatag ctagaccatt taacagtgat agggttaaga cgagtgacat caccccagat
    48001 gattggtggt tttaccccac gcataccgta tgattgtacc catccatttt tagagaagag
    48061 gtatcctgac aagttttgac cgaagtactc aaccatgtca ttacgctcaa attcaccgtg
    48121 aacaaggaca tcaaagtcaa tatcttcttg ccacttgatc cattcgtcaa tcgtttcagc
    48181 aaggaaagcg tcgtactctt tttgagacaa ttcaccttta cggtaagcca aacgtttggc
    48241 acgaacttct tttgtttgag ggaatgaacc aatcgttgtt gttggaagag ctggaagttt
    48301 aaaagcttct tcttggatag cttcacgttc tgcaaaggct ggcaaacgag tgtagtctgc
    48361 gtctgtcaag ccagcgatac gcgcacgaag ttcagcattt tcaccaacac gctcagtcgc
    48421 aaagagttct ttgttggctg caagagcttc tgaaccttga ccattgcgga tagcatccaa
    48481 gtcacggatt tcatccaatt tttcaactgc aaaggcaaag tggttcaaga gtgctggttc
    48541 aaattcttca ttagcagttg taaatggcgc atgaagaagt gagcaagagc ttgtcaaaac
    48601 gatgttttca gctgggattt gctcaagaac agccaagctc ttttcgtagt tgttacgcca
    48661 gatgttttta ccattgacaa tacctgcata gagagtcttg tcagctggga agccaccttt
    48721 aacgagttca agagttttct taccttcaac aaagtcaaga ccgatagcat ctactggtaa
    48781 gtttacaagg tcagcgtata cgtcacgaac atcaccgaaa taagtttgaa gcaagacttc
    48841 aagacctttt ttgtcagcca agagtttgtt gtaaaggttc aagaagagag ctttttcttc
    48901 agctgtcaag tcttttacaa gagccgcttc atccaattgg atgcaagtcg caccaagttc
    48961 agccaattta gcaaaaactt cttggtaagc agccactaag ctatctacga agtcgtctgc
    49021 tttcacgcct tcttcaaagt ctgacaattg aaggaaagtg aagggaccta caagaactgg
    49081 acgagtgtcc aatccaagtt cttttgcttc ttggaactca tcgaaaatct tgtgaccagc
    49141 caatttcact tgagtgtctt tttcaaattt aggaacgatg tagtggtagt tagtgttgaa
    49201 ccatttcttc attggaaggg cgcgaacgtc ccctttttct ccctggtaac cacgtcccaa
    49261 agcgaagtag cgctcaaggt cagacaagtc caagttttga actgaggcag gcactacgtt
    49321 gaaaaggaaa gccgcatcta ggaagttgtc atagtgagaa aagtcatttg atgggatttc
    49381 agtgatgcct ttttctttga cgatgttcca gtgtttagca cgcaagtctt ttgcggctgc
    49441 aaggagttct tcttctgaga tttcttttct aaagtatttt tcagttgtaa attttaattc
    49501 gcggaattcg cccaaacgag ggaaaccgat gattgtagtt gacatgatgt gtcctccaaa
    49561 atttgttgtt gaaactatct taacagaaaa gaaagcgtct gtataattgt aaaaaattag
    49621 ggtttgatat agtttgaaac tatatatctg tttcggacaa aagaaaaaga cttgaagcaa
    49681 acgtctcaaa tcctttgtat agcttgtttt atagctttat ttcagttaga cggttcaaac
    49741 gcgttattag taattcttat aagtgactat ggcttgttat tagaaaagac tataactgat
    49801 tctagtcaac tttttccctg ttcaagtggg acgactgcta gtgtctttcc taaactggct
    49861 aggactttta agactgtatc caactgagga ctagtctttc ctgtctccat cctagctatg
    49921 acaggctggc ttattccact gacttcttcc agctttttct gactgattcc ttgttcatac
    49981 ctagcctcaa tcaactcgct catgatagcc actcgcatat cactttcaag gatttcctcc
    50041 ttgctaaaga gctcagatgg acatccttcc aattactccc aatagcacta ttcttcatca
    50101 cttaaccctc ttttttttac gtctatgtat ttttaaaaaa atgagcgaat tatgattcga
    50161 tagattgacc agtgggttta aagttggtgc tagcctattt cttaagcgat tttccttttc
    50221 taggataaag catatcctgc ttgcttaacc ccaattttcc acgatgaatc caatagtaaa
    50281 tggttgaaat tcccacgtta acccctttaa ccataaccat catttcaggc gaaaattttt
    50341 ggttatgtat agtggagaat cttttccttt agtttcttaa gactgttgag cgtagtcggc
    50401 agaataaatc tctttgaagc gcccttttcc aagacattgt cggactgtcc cacgctttat
    50461 ttcagtgtgg atagtttgag gagcttttcc aagtagagag gcaatttctc tatttgattt
    50521 tccttctttt ttccatcgtt cgattaagcg acggctatcg attgtcaaat gtttgccttt
    50581 tgtagtataa ttgtcttgca tttctgtgcc ttttaatcat ttcaatctta aattggactt
    50641 tttttacttg ggttgtactt aatctataag gaagacaata aaaagaatat caatcaagta
    50701 aagtcacaaa gtcacattag ctccgagcaa ccattgcaaa ttgaggtact cacacaatga
    50761 ttaaaacatt tctctctgcc ctttcggtca ttctctttgt tatccctatc atagcttatt
    50821 ctttttttcc atcttctaat cttaatattt ggctatctac cagacctatc ttggcacaga
    50881 tttatgcctt ccccttagct actgcaacta tggcttctat tttaagtttc gtattttttt
    50941 ccctatcttt ttacaagaaa aataaacaaa tacggtttta ctctggcatt ttgctcttac
    51001 tatcgctcat attactatta tttggaacag ataaaaccct ttcttctgca tcaaataaga
    51061 ctaaaacctt aaaattagta acttggaacg tcgctaatca aatagaagca caacatattg
    51121 agcgaatttt tagccatttt gatgccgata tggctatatt ccctgaacta gctaccaata
    51181 tcagaggtga gcaagaaaac cagagaatca aactattgtt tcatcaagtt ggactttcta
    51241 tggccaacta tgatattttc acttctccac ctaccaatag tggaatagct cctgtgactg
    51301 tgattgtcaa gaaaagttat ggtttctata cagaaactaa aacttttcat acaacacggt
    51361 tcgggacaat tgtattacat tcgagaaaac aaaatatacc agatatcatt gccttgcata
    51421 ctgctcctcc tctgccaggt ttaatggaaa tctggaagca agacttaaac atcattcata
    51481 atcaattggc ttcaaaatat ccaaaggcta ttattgcagg tgattttaat gcaactatgc
    51541 gtcatggagc acttgcaaaa ataagctctc atagggacgc attaaatgta ctgccacctt
    51601 ttgaaagagg aacttggaat agccaaagtc caaaactttt taatgcaaca atagatcata
    51661 ttttattgcc taaaaaccac tactatgtta aagatttaga cattgtaagt tttcaaaact
    51721 ctgatcatag atgtattttt acagaaatca cattttaatt attttatata aaatcacccc
    51781 tctagtgttc ataaactaga gggggaattt gtatcctact atcgtttaac gcacttctgc
    51841 attgactttt tcttcgagag acgcttggat tttttccatg tagcgtgcga cttcttcgtc
    51901 cgttaagctg tcttctggat tttggaaggt caagctataa gccattgact tcataccaag
    51961 tcccagtttt tcacctgaga agacgtcaaa gagtttgata tctgtcaaac gtttcacgcc
    52021 ggcagcttgg atagcatcta caacttcttg gtgagtcact tctgccttga ggagaagggc
    52081 aacgtcacgg ctgactgctg ggaatttggt gatttccaca aatggaacag caggttggag
    52141 cgccccttcg atggctgaaa ggttaagctc agctacatac gtttctggaa tatcgtaagc
    52201 cttggcagtg actggatgca cttggccaag gaaaccaaga acttggtcac cgagtgaaat
    52261 cacggctgta cgacctggat gaaggctagc gatttcagat gttgctatat aggttacttg
    52321 gagtcccaaa cgagtaaata gggtttcaag gattccctta gcatagaaga aatcaactgg
    52381 aactgctgct gtttggaaat ctttttcagc aaccaagcct gtcaaggcaa aggcaaagct
    52441 gttgatctca tttggaagtt cttcttttgg attacctgtt tgttcaaaga cttttccaat
    52501 ctcataaagg gccaagtttt tattcttacg agccacgttg taggcaacgg tatcaaggat
    52561 ccctgaaatc atattttgac ggaggactga acgatccaca gtcattggcc acatgagttc
    52621 agtaaggtta cttggttgag ctgtgaactc aactgctttt tcaggagttg tcagagcata
    52681 ggtgatgatt tctgtcaaac ctgctccttc agcaatggta cgaacttgac ggcggagttt
    52741 ttgtgtcaca gtcaattcac cagctgtacc atcgtctttt ggaaggctgg ttggcaagcg
    52801 gtcatatcca tagatacgag cgatttcttc aaagagatca gcttcgattg tgatatccca
    52861 acgacgacgt ggtacgctga ctgtaaagct gcctgcattt ccagaaagac caaagccaag
    52921 acgacggaag acgtcttcta catcagcata agacagctca gttccgagga cacggttaac
    52981 atcagcaagg gttgaagaaa cttccacatc agaggtatca agctcacccg ctgaaacgat
    53041 acccttacgc accgtcgcac ctgcaagttc cgcaatcagg ctagctgccg catcaagggc
    53101 ttcattaact gttgccacat taattccttt ttcaaagcga gaagatgact cagaacgaag
    53161 gttcaggcga ccacttgtct tacggataga tttgccattg aaaacagcag cttcaaggat
    53221 aacacgacta gatttttcag aaatttctgt agcctgacca cccataacac cggcaagggc
    53281 tactggtttg tcagcaactg taatcacgag gtctgtctca gccaagtctc gttcttcacc
    53341 gtccagggtc actaattttt caccatcacg cgctgcacgc acacggatgt cagtcccttc
    53401 aaatgtgtcc aagtcaaaag catgcatagg ttgaccaaag tagagcagga tgtagtttgt
    53461 cacgtctaca acgttattga tgggacggat gccttcgttc atgagaaggt tttgcaacca
    53521 ttgtggactt ggtgcgatag tcacattgtc caagatacga gctgcatagt aaggcgcctt
    53581 gtctgtctca atgctgacag aaagggcatc tgccgcagct tcattagttt ctgttagagt
    53641 aaatttttta aagttgactg ccttgtcata gatggctgcc acttcgtgag ccactccaca
    53701 catagaaagg gcatctgcac ggtttggtgt gatggaaagt tcgatgattt catcatccaa
    53761 gtctaggtaa gaaaagactt cctcacctgg cacggcatct tcaggcaaga tttggatgcc
    53821 atctgcgaat tccttaggca caactgagtc agaaatcccc aattcaccaa gtgaacagat
    53881 cattccaagt gactccaaac cacggatttt tccttttttg attttgtagt tatcagcgat
    53941 acgagctcct ggaagagcca ccatgacctt gatcccagca cgcacatttg gggcaccaca
    54001 aacgatctga cgggcttctt cttcgccaac gttaacctga caaacatgga ggtgagtctc
    54061 tggcacatct tcgcaagaca agacctcacc gacaacaatt tttgagagat cagcaactgg
    54121 taattcgaca ctctctacct cgatccctgt ggttgacatt ttttcagcca actcctgtga
    54181 tggcacatca atgtccacca attcttttaa ccatttataa gatacaagca taatttagtt
    54241 ctccagaatg accattgcca cactggttct tttcctttcc tatcatttca atagaagaat
    54301 cctcttctta ccttaatttc tttctcagta accaatccgt atctactttt tgaccaacca
    54361 taaaatgatg ttggctaaat ttttcaaaac catatcgatt ataaaacgct tgagcttttg
    54421 tattatgctc ccaaacacct agccaagccc aagaaaaact attttttgta gcaagttcaa
    54481 gtgcgaattc aaacagttgc ttacctattc caaatccttg gaatttttgt agcacataga
    54541 ggcgttgaat ttcaaaagcg tcctctaatt ctctctcagt ttgagcactt ccccagttga
    54601 ctttgagaaa accagctatc tcctcctcat gcataatgaa ataggtttca gagtcaggat
    54661 ttcccaactc agttgacaaa gttttcagac tataagcctc ttcaaagtat tcctgtaact
    54721 gctcttccgt attatcatac gcaaaggttt cacgaaaggc ttgtttggca attttagcca
    54781 acacctcaac atctgccatt tctacttttc taatcattat ttaaactgtt ctgagaagcg
    54841 gacatctcct tggtagaatc cacggatatc gttgattcca taacggagca tagctacacg
    54901 ctcttgtcca agaccaaagg caaaaccaga gtatacagtc gcatcgatac cactcatttc
    54961 aaggacacgt gggtgaacca taccggctcc cataatttcg atccaacctg ttttcttaca
    55021 tacgttacag ccttctccac cacacttgaa gcaagaaaca tccacctcaa cagatggctc
    55081 tgtgaatggg aagtaagatg gacgcaaacg aatttgacgc tcttcaccaa acattttttg
    55141 gacaatcaac tgaagcgttc cttgaagatc agccatagag atatttttcc caactaccaa
    55201 gccttcgatt tggtggaatt ggtgactgtg ggtcgcatcg tccgtatcgc gacggaagac
    55261 acgccctggc gagatcatct tcaaaggacc tttagaaaaa tcatgggcat ccatagcacg
    55321 cgcctgaact ggagacgtgt gggtacggag caagatttct tcagtgatat agaaagtatc
    55381 ctgcatatca cgagctgggt ggtcttttgg aaggttcata cgttcaaagt tatagtagtc
    55441 ttgctctact tcaaaaccat ccacgacttg ataacccata ccgatgaaga tatcttcgat
    55501 ttcttcactg gtttgtgtca aaacgtgacg gtgaccagtc gcaactggac gacctggaag
    55561 cgtcacatcg atactctcgc tagccagttg agccgcgact ttcttttctt ccaagagctt
    55621 agctgtttct tcaaaagcag cagtcaagac atcacgagct tcattgacgt gtttcccgat
    55681 gattggacgc atctcagcag aaacatcttt catccctttg aggatttcag tgagcgaacc
    55741 ctttttacca aggacagaga cacgcaaatc ttgcatctct ttttcatttc cagcagtaat
    55801 ctgcttcaag ctagccagcg tttcttcgcg aagcgctttt aattgttctt caatagttga
    55861 catatttcct ccatcagtct ctcgtagata aaaagaaaac cacatgccaa aaactccact
    55921 cggagcgttg acacgcggta ccatccgttt tcatctgaca agtcagacct tcatttctaa
    55981 atccatgcgc aagtgaattc acccagcttt catatagaga gcttgcagtc acggctctcc
    56041 tccctgatat acttcccttg ggctactagt ctttcagatt cctattcaat tactacttag
    56101 tttatcagat ttttaccatt cttgcaagac ctatcttact tctgcttgtt agcttattct
    56161 tatctaactt tatagcggat tgaaataaga tgagaacaaa tcgattggga aagtaaaatt
    56221 aatttctata aatgttttag caattgtttc gtactatttt agattcagtc tactatatat
    56281 aaccaatcta tcctaagtta actatttata atcggctctc tgtaacaaaa ttaaattaat
    56341 ccccctataa aataaagagg tttagaattt gatgtcttcc aaacctcttt atttcatatt
    56401 taatgagatg ctgccttaac cgtgataata tctaatcatc aataaacaaa ctatttgaat
    56461 aaggattctc catttgattc aatcactcct ttataccaag taaaggacat tttcttatat
    56521 cgattgaatg tgccatttcc atcatcattt cgatcaacat aaatgagacc gtacctttta
    56581 gaaagttgtg cagtggacat agaaacacag tcaatacatc cccaagacgt atagcccata
    56641 atttcaacac catcctgtag agcttcagca acttgcaata aatgttcttt catatactga
    56701 attctataat catcttggac ggttaagtta ttaagttcat cttttattag ttgatcttta
    56761 gcacctaatc cattttctac tataaataat gggatttgat aacggtcata atatctattt
    56821 aaaattatac gtagtccaat tggatcaatt tgccatcccc actctgaaga ctctaaataa
    56881 ggatttacta aaccaccaat aatattccct tctcctgaat tatactgtgt tggaagagca
    56941 gattgagtta cactcatgta atagctaaag gataaaaaat ctacagtata attttttaat
    57001 aactctgcat cttcagctgc aaactctatg ttaatgtcat gttccttaaa atatcttttt
    57061 gcataattcg gataataacc tctaacatgc acatctgaaa atagataatt tagattctca
    57121 tactcatgag tcgcccatac atcttttgga tttggagtca ttggataagc tggcatagct
    57181 aataccatac accccacctt aaactctgaa ttaatctcac gagcaatttt tgtaaccaaa
    57241 ctcgaggcga ctaattcatg atgtatagct tgatataatt cttgtttcga aagattctcc
    57301 ttaggtatat ctattcctcc actagtaaac ggtaattcca aaacagagtt tacttcgtta
    57361 aatgtaagcc aatatttaac tttatcttta tacctttcta aaactgttcg agcaaatttt
    57421 tcataaaaat gaatcattct cctatcaatc catccatgat attttcttgc taaatataat
    57481 ggagtctcat agtgtgaaag agttacaagt ggttctatcc cgtgagcatg tagttcatca
    57541 aacaattcat cataatattt caacccagct tcgttaggtt cttcctcatc tccttttgga
    57601 aaaattctac tccatgcaat agaagtacga aaaacattaa agcccatttc agaaaacaag
    57661 gatatatctt ccttatattt atgataaaaa tcaataccta tcaattttaa gttatcttct
    57721 gtaggatttt ctgttgcttc tcctaatcca cctttgggta acacatcctg aactgataag
    57781 cccttaccat cttcattata tgctccctct acttgattag ctgcaacagc tccaccccaa
    57841 agaaaatcat ctggaaaaat ggtcataact ttcctccatt ataatattac cagtaattcc
    57901 ttagaatgct cgattgtctg attattaggt aatattaata catctagaaa atcattggta
    57961 ttcgttacaa ttactggtgt aactgtttcg tagcctttag tcttgattaa attcaagtcc
    58021 atttcaaaaa tcaactgatt tttgaaaact ctgtctcctt cttctacatg actaataaaa
    58081 ccttgacctt ttagctcaac agtatctaat ccaatatgaa ttagtaactc aacaccctca
    58141 tcactcttca atccaattgc gtgcttagtc ggaaaaatat ttgtaatttt cccatcaaat
    58201 ggtgcataaa ccttaccttc acttgggata atcgctactc cgtctccaat tagtttatct
    58261 gaaaatgttt tatcctggac atcgcttaac ggaatgattt ctcctgatat aggagaaaat
    58321 atcatttttt tatttgaaac tccagcttta acttctaaat tgctagaact ctcttcttca
    58381 tcgattccaa atatataagc taatacaaag gtaataacaa ccgaaataac cgccacaatt
    58441 aaagcattta caatatttga tggtacatca gaataaataa attgaggcaa cgctatcaaa
    58501 gatgggacag caaatagata cgctttaaca ctagtaagac ctgcaaataa tcccgctaat
    58561 ccaccaccaa tcatagctgc ataaagcggt tttttatatt ttaaagtcac accatataat
    58621 gcaggttcgg taatccctgc aagtaaggct gagaaacctg ctgcaaaagc aatttgtttt
    58681 gtattattat ttttactctt taatgcaaca gccatcgaag cagccccttg agctaagttt
    58741 gaccctaaca ttgctggaag aattaatacg tctggagtag caatagatgc cgccaaaaaa
    58801 ataggtgcaa aagcccaatg cattccagtc ataacaataa atggcataat agcaccaaga
    58861 atagctaatg taagccatcc agctacacca tacatttgcc caactagatt tgataatcct
    58921 tcaccaacaa ttactccaat aggtccgact acaactaagg caatacagct tgatactaat
    58981 aatactagcg taggttgcaa aaaactctta gtaacagctg gtgttaattt agcaatcatt
    59041 ttttcaatat atttcatcaa ccaaaccata ataagaattg gaacgactga cgaaccataa
    59101 ctagctggtg tcacaggtgc accaaataaa ctaagaggat tccctgattg caccatttga
    59161 acaaaatttg gatggagaag tacacctgct acagacatag ctaatgtaga tgttactttt
    59221 aatttttgtg atgcagaata agctaataac agcggtaaga aataatatgg agcatcccca
    59281 aaaaatgtca aaaaagcaat agtctgagaa tctgattgca atataccaag cattggtaaa
    59341 ataattacca agactttcag catacctccc cctaacattg ctggaatgat tggagtcatg
    59401 gaaccagcga tatattcaat gattctttct aaaatattcc ctttgtgccc ttgaacaact
    59461 gaatcggatt caaaattgcc aagtttaacg aattctttat aataattagc tacatcatta
    59521 ccaagtataa tttgatattg tccattcttt ttcataatac ctattacacc tggtatcttc
    59581 ttcacatcat catcattgac taaattttca tcttttaatt ctaatcttaa acgtgttaca
    59641 caatgggtaa ctctattgac atttttttca cctccaatta catcgaggat tttttgtacc
    59701 gtatctttat aactcatggt attctcctat tctattaatc taaatttttt gttaagcgac
    59761 gaatatgagc catcaaataa actaattcac tagaagtcaa caaataattg tactcagttt
    59821 gtataaacat tgccacctgt tcaccacatt catattctct aggatattta tttttcatta
    59881 atgctaacaa gtcttcatca tcatcgtcac aataagttgt attttcaacc aagcgatggg
    59941 caaataattt tatatgagtt atgaatctat aataatcaat agaatcttgg ttaaactcag
    60001 tacaatagaa atcttgaatg attttctcaa ttcccataat tatttcagtg attttatacg
    60061 actcttgaaa attattttct aaattagcat taacaaaatg tagcgctatg aatgcagctt
    60121 cgtcaattgg aagttcaata cctaactctt tttttattat ttgtaaagcc cttttcccaa
    60181 gttcaaattc ttctttataa tatttcgaga tttcccagcg taggggattc gaaataataa
    60241 ctccttcctt ataacgttct atgctcgaag aaatatgatc cgttaaatta atatagataa
    60301 tttcatcaaa attattaccc aatgttattt tacctaggtt aattattttt tcggtgatgt
    60361 acaccaactc caaaggaacg ttaataaaca tctctgtaaa acgggtcata ttatctctat
    60421 ttttgagaaa aaaacttttc tcaatatcaa ttggatttac tttatctcca atttttcttc
    60481 caaaagctat tccccttcca aaaagaagaa tatcgatatc ttttttactt tgcgcaatta
    60541 cggcattgtg gtttagtatt cgttttatga tcataaaatt tcccttttaa aataaaagga
    60601 acctacttaa aaaacatcaa gaaacttctt ctgatgtgat taaataggtt cctgctcact
    60661 tgtattagtg ataacatcct tttatttcaa tttttaatgg tgacatgaag cttaaataat
    60721 caataactct gtaaccgttt ttattttatg atatttcaat ctatttgtca agtacttata
    60781 aaaatttttt tattttgtgt gattcgaatg tgataatggc aacagtctca ctaaagaaat
    60841 gaaaatcata catagaaatt tttaaaaatt ttctctatcg taaacctgcc actagttcag
    60901 aaactatact agctgattcc aaacgtaata tggtcatctc atctaccttc cctaataatg
    60961 gcattgcacc ataccaaaca atagtcttat tcaccaaaag aataggcgtt actatttttg
    61021 attgagtaaa agacacttta attttctggc tcttcaactg gtctagccat gctttatttg
    61081 caaccgtctc tggtatacat atctcaattt gactaatcct aaattctttt agaaaattca
    61141 tcagttttgt ctggtgcaca taaggtaaaa taagcagaca ttcctgtctt tcccctgcta
    61201 agtcctctct caacaccttc tcatatctac tatcaacata aacgaattgt ttctcctcac
    61261 cctcaatggc acgataatcc atctttcgat aagctacttg tcgtttctga aacatctttt
    61321 ctaaataagg aacatgaata tccacataat cgaaaatccg caccaaagac ttatccttgt
    61381 agtttctatg aatccgacct gagtactgaa tcaaattatt tttccaagaa aagggtgctg
    61441 ccaagataag cgtgtccaac tgaggtaagt caaaaccttc gccaatgtat tttccagtag
    61501 acaacaaaac aaacccttta tctaactgtt ctaacgtctc cagtaaactc gttctctttc
    61561 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
    61621 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
    61681 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
    61741 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatttctc tgaaaaacaa
    61801 taggttcatg accattctta cgctcaggcg tagccgtcaa accgtaaaga tacttccctc
    61861 taaactgagc aacaactttt tcaaacatca aggcagagat atgatgacac tcatccacaa
    61921 tcatcatctc atactcatcc aaaagacttt gactattttc caacttaaat agagattgaa
    61981 tcataacaac atcaaccagt ttactcagtc atttcttagc cccaccgtac tgcccgacat
    62041 agcctattac cctttcacga cctgatggtg tataacgggt agcttctgcc tcttcgaaag
    62101 tcaaaaaaca ctttaaacga tccagtcatt ggtctaagag ttgtctatta tgaactagga
    62161 taatggtttt tgtcttacgt tcagagataa gagcagcacc taaaacgatc tttccaaaac
    62221 ctgtcccgca tgaagtaaac cattttcttt agaattcata tctgacaggg ctaattcttg
    62281 ctccaaagta agctctccct taaatgctac tctaatagac ctttgtactt ttctcctatc
    62341 ctccacaact acctgcttaa atttatcttg caatggatat aacaagcctc ttggcagcca
    62401 taaataataa tcggattctc caaataaata cattcgctca ggaatttgat aggttggctg
    62461 tcgcatagcc tgctttaaat ataataaaat gaaataataa caggacaaat cgatcaggaa
    62521 agtcaaatcg atttctaaca atgttttaga agcagaggta tactattcta gtttcaatct
    62581 actataaaat tcgggattag aaaaggaagc catatttttc aagaaaaaaa gtgccttgga
    62641 tgtcacagac gatttttcaa gttggatcat attggataaa acgaccttca actccttatc
    62701 caattcttgc ttgcctaact cctcttggat taacagtgcc actttagcag ttgaaatcct
    62761 ctgaatttct tgtagatacc tccattgatc ttcataaggc tgaaaatgtt catccacaaa
    62821 gaccgttcgc ccttgatgat aagcttctcc ttgaaaagga agggaaatta aattatcaaa
    62881 tccaccttta ggaagaacat cctgatttgg aaacatgcca tcaaaagaat caaaggacag
    62941 ttgcatactt tcctgcatag ccaattctaa tagtttcttt ccaaacaggc gagcctttcg
    63001 actcagaatc gcttcctcaa agaagaacca aatatggagt ccgtaacccg aacgagaaat
    63061 ctctaaatgg gcttccatct ggcgttccct tgctattctt cgaatggtta aaccagcttc
    63121 tttccaatct ccttcatcca aatccagtac caaaaaataa cagctatcat ctaagtgcat
    63181 aggaaagata ccgatagctg cctccccacg aaaatgagat ttcaaaacgg agttcgtcaa
    63241 tgtctggaaa ctccgttttt caggtggcaa ctgcttccaa ccataatcat aggaaggaaa
    63301 atactgaatt ttcccttgtt cattgataaa attcttagca taaacatcat aacgtccagc
    63361 aaacacggag gtaaacaatt gtaatttttc ttgcgtcgtc aagtgactac tttgaagttg
    63421 gaacatctcc tcgaaccgag agcgttccat cacaaactga ctcttgtctt taagacgttt
    63481 acagtggaat gaaataagat atgaacaaat tgattaggaa aatcaaatta atttatagaa
    63541 atcttttagc agtcatggcg tcctattcca gcttcaaaat gctatacaca agaaaaactc
    63601 actatcccca ttaaaagaaa aaaagacatc aagtatttct accacaattc catccaaaga
    63661 cgcaaaaaca gccataagag tcacctcctt gattcctata ggctgattat aacaagaata
    63721 gctgaaattg tacacgaaaa taaaatccga atagcactca ttttgtatgc gactaatagt
    63781 ccatctcgct ccggaatgta cgaagtaaat agagtttaaa cgagcagtct ataaaattca
    63841 aaaaacgcat attatcaagc gacctaaaac tttgatgata tacgttttct tgtgagaata
    63901 tttacttcat ttttgcctaa aattcaatgt ttactcagta tttggattat gaaaaatcga
    63961 ggtctaaatc tagatacatt ttttctgaag acaaatcatt ttgaccaccg agcaagagat
    64021 tttcaaaaaa agctgttaaa aactcaggac gtcgctgtaa aatctttgca ttatctaata
    64081 ccaaggcatc acgaaaatac ttggaatgtt gctgaaatgg tatattatca atatcaaaac
    64141 caaactcacg aagatactga atcaaaaaga ccgttactgt ccgagtgttt ccttcgcgaa
    64201 atggatgaat ctgccagatt cctgaaataa aatgctggat ttgtttaacc acatccgcct
    64261 gagttagtgt cgcatatgca acttgttttt cctgattaaa atcataatcc aaggtcattt
    64321 gaatcatgga gtaatcagag tacacaacac tttcaccatt caaaacaggt tcattctttg
    64381 tgatattggt ctgacgaaat tgccccaccg gaatagaggg ttcaaatata tcttgaaaca
    64441 actccttatg aatagcaagt aaggtcgcag gactaaatct aaaacctctt cgagacaaga
    64501 gttctacgat acgcaaagaa accaagtctg cctcctccgt actcgcatca acggtatgat
    64561 gataaaccgt tgcatcctca taaacctgct cataagtcag ttcaccccgg gactgtttct
    64621 cagccaaaga ttccatatac gctgatggca ctagattgtc aactttctgc agaccaaaac
    64681 ctatccgcca taaatcacgc ttcgcttcat aagacaagtt tggattgtca atgttgtaag
    64741 ttggttgcat agaaatatcc tttcaattgt ttttctgtgt catcggtaaa ttgtgaaata
    64801 ggtatggaat tggcgaaaat tataaaaatc cttcacaata ggttctatga aatatatata
    64861 cttcatctta atagtgagca agctaaactt agcatttcat gccctcatat gggatgttct
    64921 ttgactaaat aatatgatta tcgagatata tctggataaa tgaactaata agtctgacgc
    64981 gtagacttat caaagtcatt ggcatacacc actatgaact cgttggtctg ttcaaatccc
    65041 aacacattac ctgagaagaa agttgcaatg ttgtttttgg tgcgggtttg aatttaaaaa
    65101 atttgttatg tagtacctaa tctaaggaat tagaacaatg cctctaattt ttctttaata
    65161 cactgaaaca ttgatgattc tggctgtatt tttgaaacag ctcttctttg ctcctggaaa
    65221 atatcttcag aagttatatt ctctattcct aacgctactt gagttttttt tctaaaatat
    65281 tcttttccgt tgccatcttt agaaaaatca taaccttccc tatctacgct gttacacaaa
    65341 ttagctaaaa aaaactctgg ggttgggaaa ggaagataag aaacgtattt agcccaataa
    65401 tctataaagc ttctttgttt cgcaattaat tcaatattat ttttttgccc tttattacct
    65461 gaaacattaa atttaattgg acatcccgtt atcaatttta taatatcatc aagattttta
    65521 ttatctgatt caggaatttt atctgatata acaacaccat tttcaagata gttcattaaa
    65581 ttatttgatt cactaacatt agtgttttga tctccatcaa gccaaaaata atggttatcg
    65641 gaatctaaat acgatgagtt taaaatatta ttacaaatta tttgatttgc tccaccagga
    65701 atatatctca ctactaaatt ctgtttaaga ttctcactac ctgaatgagt gataacaaac
    65761 tctagaatat atttagctag tctatcttca acataaatca tcttcctaga atgatacaca
    65821 tcacctaatt caaaaaatgc atcctgataa tcaatatttt caataacatc taccttttct
    65881 ccgtttttca ctaaaagttt cacggcttct ctaggaaaat cttttataag ttgtgtagaa
    65941 tgtgtagtga taataatttg atgtttttta tttaaacact cttgaagtaa aaactcttta
    66001 aatttataga ttgcactcgg atgaagtgag atttcaggtt catctattaa tattaatgaa
    66061 tttgattgcg catttactat atcatttact aacaaaataa ttctagcctc acctgttcct
    66121 gcaaaagcct cggaatattc ttttccagat tttttcatcc aaatagtttt ggaagctttt
    66181 atatcatcac cttttgaata caacttatgt gttaaaattt gaatgtctgt ataagattca
    66241 tccattattt cactaataat ttcacaaact ttatcatcaa ctttaacatt atctataacc
    66301 atttcctttt tataacgcgt atagctactt gtattattct ttaaaatatc agcaactggt
    66361 ttagatcgta atcttataaa atcttgttta ctacgttgag tagaaatttt tttaaaatta
    66421 tagtgataga aaaataaatc aaaagcagaa acatattctt tacaatcaca aaagacaaca
    66481 tttttttcaa tgccatccca tctgtctgtc gaagaacttc caatatattt atttttgggt
    66541 aatctttcca tctcatattg tttttgagga gcatatggtt cccaataatc taatcctttt
    66601 tttgttccag aacggccttt aagaacttct acatttctag aagctttaat gttataatat
    66661 gaatagatta aacattgttt cccatccact tcatctattt gatcaacatt tgtactaaac
    66721 caatattcag acacactttt attggctgga gaaccatata aagcttgtaa aattgaagtt
    66781 ttatttactc catttctacc aactaataaa gtaataggga aattaaaatt tattcttgaa
    66841 tttaatgata agctcttgta atgaggaaat cgtatataat caatataagg ataaaattga
    66901 tttttatttt taaaaaaatt tttagttatt ccttctaaac tctcaattat ctgattgtcc
    66961 atttgctatc tccctataaa ctgacataaa ataatttcca ctagcttgag ctaattttac
    67021 tggaactgca ttaccaattt gcttagctaa ttgacctcta tttccaacaa aaatatagtc
    67081 atcatcaaaa gactgtaatc ttgcagcttc tcttgcactt aaagctctat tttgagttgg
    67141 gtgcccaaat ctaccttttg aatatgacat acaccctcct gtaatagtaa tggaaggttt
    67201 gttgatatct aatattccat atacgtcact atgacctaaa cgatttttat gacaatttaa
    67261 ttctaaagat tttggcaaag aggttctact tcccccatta tttctaatat gagtaattct
    67321 ctcaatattt aaattagata gtttgtttgc aacatgattg tagatacctt ctccaatata
    67381 ttcttcacca ccttcaatag gaggcaagtc cattattata tccgcattaa tccatgaaag
    67441 aaggtccaat tctggtatat ttgaatgagt tttggaaggc aaattcaaag ttaaattcgt
    67501 gttatcaaga atttcttttc taattccgtg taacaccaat ctttttctag attgaggaac
    67561 tccataatca gctgtattta aaatgtcata aataacacta taattattat cgattgatgt
    67621 caaaaatttt ttaaagattt tttcatttct tgttctagtc atacccacaa cattttccat
    67681 taatagaaaa tcaggattca attcattaat caaacgaaga aattgaaaaa caagttgatt
    67741 cctctcgtca ttttcattat tagtaccaat agttgaaaaa ccttgacatg gtgggcatgc
    67801 cacgagcatt agtttatcgt ctgtatcaat tttaagatac tcttttactt catctcctga
    67861 tactacattt atatctttat ctattacaga cacctcagga ttatttaact tataagtttt
    67921 aacagctacg gaatcaattt caacagcaac ttgaacatct atgcctgatt ttttaaggcc
    67981 acttgtagtg ccacctgcac cgctaaataa atcaatagca acaattttcc ccatagtatt
    68041 ctcctaaagt ttctcctttt tattataaca ttatcaaatg taaaacccaa cccgataggg
    68101 ttaggttttt aacatcattt caccaacttc ttcatctcat caatacgtgc tacggtcgca
    68161 tcatacttgg cttggtagtc agcttgtttg tcgcgttctt tttggacgac ttctggtttg
    68221 gcgttggcta cgaagcgttc gttagagagt ttcttaccaa ccatgtccag ttctttctgc
    68281 catttggcaa gttctttttc cagacgtgcc aattcttctt cgacattgag gagatcggcc
    68341 agtggcaggt agatttctgc tcctgtgatg acacttgaca tagccagttc aggtgcaggg
    68401 atggttgatg cgatttccaa gtgttctgga tttgtaaagc gtttgatata gttgacattg
    68461 ctgttaaaga aggcttccaa gtcgctatcg cttgtcttaa caaggatggt gataggtttg
    68521 ctttgtgcta cgtttacttc cgcacgcgca ttccgaacag cacgaatcaa gtttttgaga
    68581 ctttccacac cagtgtgagc cgcaaggtct tcaaaggcta gattaacagt tgggtatgca
    68641 gctgtcacga tagaaccttc tgagatttgt ccaaagattt cctctgtcac gaatggcatg
    68701 attgggtgaa ggagacgaag gatcttgtcc agagtgtaaa ggagaacaga acgtgtgatg
    68761 actttctctt cttcattatc gctataaagg acttccttgg tcaactcaac ataccagtcc
    68821 gcaaattcat cccagatgaa gttgtagagg atgtggccag caacaccaaa ctcaaactta
    68881 tcaaagttag cagttgcttt tccaatcgtt tcattgaggt tgtggagaat ccagcggtcc
    68941 gtcacattac cagcctcacc tgttgcaact ttttcgacat tggcagttgc ttgctcaagg
    69001 ggcaaacctt cattgttcat aaggatgtag cgagagatgt tccagatctt gttaatgaag
    69061 ttccatgaag catccatttt ctcataagag aaacgcacgt cttgtcctgg cgcagaaccg
    69121 tttgaaagga accatcgaag ggcatcggca ccgtatttct cgataacatc cattgggtca
    69181 atcccgttac cgagagactt agacatcttg cgtccttgct cgtcacgaat aagaccgtgg
    69241 ataaggacgt tttggaatgg ttgacggcct gtgaattcca atgactggaa gatcatacga
    69301 gacacccaga agaagatgat gtcgtaacct gttaccaagg ttgaagttgg gaaataacgt
    69361 ttaaagtctt ctgagtcgac ttcaggccag cccatggttg aaaatggcca aagagcagaa
    69421 ctaaaccacg tatcaagcac atctgaatcc tgagtccagt cgtctccttc tggtgcctct
    69481 tctcccacat aaatctcacc tgcctcgttg taccaagcag ggatttggtg accccaccag
    69541 agctgacgag agataaccca gtcgtggaca ttttccatcc attgaaggaa ggtatcgttg
    69601 aagcgcggtg ggtaaaattc gaccttgtcc tctgtgtctt ggttggcaat ggcgttctta
    69661 gccaattggt ccatcttgac gaaccattga gtagacaagc gtggctcaac tacgacacct
    69721 gtacgttctg agtgaccaac actgtggaca cgtttttcga ttttgacaag ggcaccgatt
    69781 tcttccaact tagcaacgac tgccttacga gcttcaaaac gatccatgcc tgaaaattca
    69841 aaggcaagct cgttcatagt tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga
    69901 cgttggccaa ccaagaagtc atttggatcg tgggcaggtg tgattttcac gacaccagta
    69961 ccaaactcag gatctgcgtg ctcatctcca acgattggga tgagtttatt agcgattgga
    70021 aggatgacgt ttttaccaat caagtccttg tagcgcgggt cttctggatt aaccgcaatc
    70081 gcaacgtccc caaacatagt ctcaggacga gttgtagcaa cttcaagggc gcgtgaacca
    70141 tcttccagca tgtaattcat gtggtagaag gcaccttcca catccttgtg aatcacctca
    70201 atatcagaaa gggctgtgcg agctgctggg tcccagttga tgataaactc accacggtag
    70261 atccagcctt tcttgtaaag gtccacaaag accttacgaa cagcttttga caaaccttcg
    70321 tcaagagtga aacgctcacg agaatagtct acagagagcc ccatcttgcc ccattgttcc
    70381 ttgatggtag tggcatattc gtctttccat tcccagactt tcgtcaagaa agactcacga
    70441 ccaaggtcat agcgggaaat gccctcacca cgcaagcgct cctcaacctt agcctgagtc
    70501 gcaataccag cgtggtccat tcctggaagc caaagcgtat caaaaccttg catgcgtttt
    70561 tgacggatga taatatcttg caaagttgta tcccaagcgt gaccaagatg aagtttacct
    70621 gtaacgtttg gtggtggaat aacgattgaa taaggcttag ccttttgatc gcctgaaggc
    70681 ttgaaaacat cagcatcaag ccatttttgg taacgaccag cctcaacctc ggctggattg
    70741 tatttagatg aaagttcttt agacatgtgt gtgtcctttc tctattttgt ttattttatt
    70801 ttgaatttgc ttagcagctt cttctgcaga caaattcgta ttatttattt taaagtagtg
    70861 gtgcaactca ttcggttgat attggaaatt taattgaagt gtttcagcgg tctctaaaat
    70921 ttctctttca gatacctcaa tatgtcgttt taagggtttg tgctttaatc gattctccgt
    70981 tcgatttcga cgtatgcact cttcaagact tgcttccaac tcaacaaaaa gaatctcttg
    71041 atgataatca tccaacaaat tctgaatttg ctttaaatat atcagatgat actgatttga
    71101 aaaatcaatt acatctgtta aaattactga tcgctgattt cttgcacttg ctccaaggaa
    71161 agaaaaggta attccacgaa caaattccca catctcctcg gtataatcct gatagatttc
    71221 tagtgcaaaa tcgatggctt gatggttata aaagagggta gaatccgtca gtcgagataa
    71281 ttcttgacca atggtcattt ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa
    71341 atcacctccc actcgctctt cagcaagcca tatatcagac tgtcacagcg gtttccttga
    71401 acatcctttc ggtctcttat gcgagcttcg agggtaaagc caagcttttc cgcgactcgt
    71461 ttactttgaa ggttatatcc aaagcaagtt agttcaatct tgtgaagacc caaatcttta
    71521 aaggctaagt caatcaaggc acgcgcagct tctggcacat aacctcgccc ccaatagtct
    71581 gggtgtaagg tatagccgat ttccagcaca tcatcttcat ggcgatggtt gaaatcgaca
    71641 gagcaaacga tcttatccgt tcctttgacg acaatcccgt agcctgctgg gagattttcc
    71701 ttttgattac gctccggaag aatgtgctcc agataataaa tctcatcttc caaggtcttg
    71761 actggaggaa aaactgctgg ataggcgacc tctggcaaac tagcatagtc aaagatatcc
    71821 tcagcatccg ccacagtacg gactcgtaaa acgagacgtt ctgtttcgat tttatctggc
    71881 agctcagttc ttgccatcct tcttcctcgc ttttttgatg aaactgccct tcatatctac
    71941 acgcttatcc agatagcgat aaacgcgctg atatccatct cccatgaaat aggttggggc
    72001 aaacagttga tttttaaaat gtcccttttc atccaggagt tctggggcaa caagtcgctc
    72061 aagaatcttg gcaaagatgt ggcaaatacc gtcttcctca acaatcctat ctaccctaca
    72121 atctaaaaca agtggacagg cgtctaaaat aggagtctga gttcgttcag aaatttcata
    72181 atgcactccc aaacgttcca atttctcctg atgactgata aaaccagcct gctccatcgc
    72241 aagcatagaa gtttcatcag aaatattcac agtaaatttt tgatactgtt tgatctgctc
    72301 tgcggcattc tctctcgcaa cgactccaat cacaacccaa tctcctagac tatacgagga
    72361 actacaggtc gtgatgttat agccaaaatt ctaatcttga tatcctaaaa taaaaacagg
    72421 aaaaccataa tatagtttat tagttttaaa tgattgtttt ataacaacct cctttgacta
    72481 agacacaaaa gaaaagccct gccatctaca tgacagggac gaatgtgttt atccgcggta
    72541 ccacccaatt tcgggccaag cccgcatctt tagtctttaa aataaaaaga cagaaatatt
    72601 tcattttttc agtcattagc aaccagtttt gacacatttg tggacttctc agcgccgcca
    72661 ctttctgtaa aatgtgggat tcaaaacacc tctaatggct ctattgtagc aagtttttct
    72721 cggaaatgca aggctcaaga aaaattactt gaacttgatg ccatcttctt tcaatttctt
    72781 aatggtagct gggccgattc ctttcaaggc aaggagttct ttttcagtcc agtttttgaa
    72841 atctgaagca gacttgattc cttcatcata gaaagtcttg gcacgatcaa gtggaagtcc
    72901 acccaagttt gctgcaaaat cttctacaga attagctact ttttgagctt gctctttggt
    72961 agcttctact gcttgttcaa cttttttaga aacagcctta ccagctgcgc ttgctgactg
    73021 ttctgcacgc ttcacgactt tttttgtctc atctacaacc ttagtcacag tacttgaaaa
    73081 ggcacctgcg cgacggaggc catttcgtaa ttgtttttta cgattgagtt tctttgacat
    73141 gataaaatcc tttcaataaa aaatccctgc tctgacaagg atttaacata aacattctat
    73201 caagatttta gtgaaaaatc aagaatcttt ctcgtttaat aatttcgctc accaaacaag
    73261 ccttctggca aatcatggaa tcccttgcct actttgaagt tttcaaactt accaagcaag
    73321 aactgataag catccaagcg actctcatag cgaatcatgg catctttggc acgctcgtcc
    73381 tggtcttctt cgtaaacttt ttggctttcc ttgtgcgcca tgtcgttaat catgatttgg
    73441 gcattgaccc aagcttcaaa ttccttcata aattcttgtt cgtaactcat tttttctcct
    73501 tattctaatc cacggaaata gtccgtatca atctcacggt agggctggat atcctgaacg
    73561 tattccagta caccttggaa ttctccgttt tcatcgtgta ctgcagcata ggtgatgtgg
    73621 acaaacttgc ctcgcgactc agacttgaac cacatttcat acttgtcctt ggtcccctca
    73681 cgaagtccct tcatgatagc cttgaccttg tccaaatact taggcggatg acagagttcg
    73741 acattgcgcc cgacttggga cggcgtccgt ttgaaaatca tctcatcagc tggcgtattg
    73801 tcattgtaat actggaaaat atcttcttta ttgacaaagg taatctccat agggagatga
    73861 ttgaggatga gattggcctg ctcgactgaa agatagccat taccaaaagc ctgttgacta
    73921 tggcggtcca gcacagcttc cttttcctta ggggtaaagg taatggtaaa atggccttct
    73981 ggcgtatcta tgacttgttg aacttgacct tctgccgtat ctagctgtac aggctcctct
    74041 gcaatctttt cctcaataaa gctctgtcgt tctggcaccc atttctctga cggacggatg
    74101 atggcatagc cataggcatc gctctcctcc gcaatctgaa gccagtcatc ctgagtaaaa
    74161 gactcaagga gaatcatgag gaggatggac tcttccttga aaatcatact ttcaaactct
    74221 gtcgcaaaag cttcaaaagc ttcctttaca ctgctaattg acacttctgg tagtgacttg
    74281 gctgtcgtta gagctgtttg aaagagttcc ctaatctgat catccactcc ccacataact
    74341 ttgggaggtg aatcgtgtcc atagcgctcc atgataggaa agaagagttc ttctttacgt
    74401 tggtaatgga tgtcaaattg ccccacaagt cccatctgac gcaccaagcc cttgcgcatc
    74461 tccgcaagca tttcctcgtc ttccatcaac tcataggtat ctaacaatct acgaatgcga
    74521 atcaaagctg cacggagggc caaattttct tccttaaaga cacgaactgg gtgcccaggg
    74581 tgttcggtat ctaaaacttc gacacctttg atagcatttt taaaaagatt ggcatggaca
    74641 tcacagagtt ccataacatc ttcaaaggtg acacctgagt ctgagttcat cagctcgtgc
    74701 tccataaggg aaatctcaat ggctgagaca cccgcaaagg tcgcatcaaa acgctcctga
    74761 accgactcag gagaggcgcc attatgcaat tctaataaaa tatcccgtag gacatgaatc
    74821 tgttcatctg ccattagtct aatccaatca cttcgtagcc attcgcttcc agtgtgcgta
    74881 caatcttgtc cataggagtt cctgctagct tagaaccttg tttgagcgat accttgcgac
    74941 cgactgtgtt gcgcatcaag ggattggcaa ggggtttaaa acccagctcc actagaattt
    75001 ccaagacttc tggatgcttg tccaccactt ctgcaacagg aattgacaca tcgatgatat
    75061 tgtccatgac gacctccatt atatgttcta atactcaatg aaaatcaaag agcaaactag
    75121 gaagctagcc gcaggttgct caaaacagtg ctttgaggtt gtagatagaa ctgacgaagt
    75181 cagctcaaaa caccgttttg aggttgtgga tagaactgac gaagtcagta acatatatac
    75241 agcaaggtga agctgacgtg gtttgaagag attttcgaag agtataaaat gattttactg
    75301 cttatattat accatatgga gagagattaa aaaactagca gtggggttcc tgctagtttt
    75361 ctgcgacttg gattaccatc tagataagtt taaagaacca atccaatatc ttgtaaaaca
    75421 gcaattgaac tgcaaaagaa atgatcatcc aaaagaattt cacaatccca ataatcggtt
    75481 tgataaaaat aatggtaaga agtccccaga aaaatttcat tttttatcct ctggcttaat
    75541 gagccaccga gccgtatcca ttaacttgtc ggcaataaaa agtttcccca gaccgacaac
    75601 ggcattatca tctttcttta tcgttttcat tacttttaca ccttgcacgg tcaaaaagta
    75661 attaccataa attttagcta gagtttttat gagtcccata ttactctcct tcgatgattt
    75721 cagcctcttt tcggattgtt tcaacatctt cttgatattg aacttcacta tagttaacta
    75781 gcttggacaa ttctttctgc aagctttcac ccatcggttt catagttgca aaggttaaac
    75841 cacctgaaat gataccaccc aagataggaa taaatttccc cattcctttg gccagccctc
    75901 ccttggtaag attcacacca aatattctta agactttttt caaaatagga taccaaagcg
    75961 tctttgttaa agctttatta ggtactgttt tcattacctg tttggcaatt gttataccac
    76021 cagcacgtag caaagcagca gttccattca cccccaacat gacgcctaga taaagcaaga
    76081 gggtattttg agcatcttca ctcaactcct cgcgtgaagc ccaaagatcc tcataaccat
    76141 aaatataacc taattcttgg gccaatttca gagagaaacc ataaaattga gccacatcag
    76201 ctggaatggt aattgccata gcaagccctc caggtaatcc tgccaaaaca gaagtcccac
    76261 tcgctaataa tacattgtcc cgaatacaag cattagctac acgatctaat atttcttgag
    76321 atagaagagt cgttggacct tgttccaata aggtaggaat atcttttgga tccaattctt
    76381 tggaaaactt atccactaaa aatttcgaac gttcaacctt aacaactggt agttttacca
    76441 cttgttgtaa tacttgcata gctaagtctt gttcagccat atacaaactc cttatttctt
    76501 ttttacacct tatcatatta tatttcctac aaaaaaagca ttttctaatt agataacatt
    76561 aaaaaataca gaaccccttt tttatagtaa aatgaaacaa gaacaggaca aatcgatcag
    76621 gacagtcaaa tcgatttcta acaatgtttt agaagtagat gcgtactatt ctagtttcaa
    76681 tatattttaa aagaatattt ttccatttca aattcaacct attttcctcc accaaaaaag
    76741 aggggcaacc cctcttcttt agttcttatc cagattgcgt agcatctcgt caatcttgtt
    76801 tccatactcg atggactcgt ctttgacgaa ggtcaaatct gggattttgt acaatttcaa
    76861 attgcgacca agttcacgtt tgatggtacc agttgctttt tcaagcccga tttgggcttt
    76921 ttggttatcc gaagcaaggt tactcaaaat ggtgtaataa accttggcaa cagacaagtc
    76981 acccagcatc tgaacatctg tgatggtcac accttggaca cgtggatcac ggactttctt
    77041 ttgcaaaatc tcattgacct cacgcttgat ttccatgccc acacgatctg tacggaaatg
    77101 atttgccatg atattccttt ctctactttg aaccaaaagc taggccagca gacctagcta
    77161 ttttaaactt cttgattgtc agtttaaatt gaaacgaagt tcaatttgaa gtcatctgct
    77221 tctttcgccg tggtgaaagt gatggaactg atttatcagt cccatcacag gggatttttg
    77281 agaccctagg ctcaaaaata agcaatgaaa ccatcggttt gcttgcgtcc ctcaccacct
    77341 aagaaaggag caaaaaatct tatctcttga tttcttccat gacatacgcc tcaatcacat
    77401 catccatctt aatatcattg tagccgtcga tcatcaatcc accttcacgg ccgtttgtaa
    77461 cttccttaac gtcgtcttta tagtgtttca agcttgcgag ttcaccatca tagataacga
    77521 caccatcacg gataacacgg actttagagt cacgggcaac cttaccgttg ataaccataa
    77581 atccaccgat agttcccact ttagacacct tgaaggtttc acggataacc gcttcaccaa
    77641 taactttttc ttcaaattct ggatcaagca tccctttcat agcttcttcc atctcttcga
    77701 taaccttgta gataatgctg tgaagacgga tttccacatc gtcagcttct gcttgttgac
    77761 gagcttgtgg tgtagggcgt acgttgaaac caacgataaa ggcatttgaa gcttcggcaa
    77821 gggtcacgtc tgattcgttg atagcaccaa ccgctgagtg gacgatagtc actttgacac
    77881 cttccacgtc aatcttttga agtgaggcag aaagggcttc aacagaacct tgtacatcgg
    77941 ccttgatgat aacattaaca gatttgagtt ccccagcttt aagggtatca aagaggtttt
    78001 caaggctaac acgttgggta gcttgacgtt gtttcatgag ggcacgtttg gcacgctctt
    78061 cacctgctgc acgcgcagat ttttcatcct cgtaaacggc aaagtggtca cccgccatcg
    78121 gtgcttcgtt caaacctgtg atagagactg gtgttgatgg tccagcaact ttaacacgac
    78181 gaccaaggtc gttggtcata gcacggacac gaccgaaggt atttccgaca acgattgggt
    78241 cttgaacatt caaggtacct tgttgtacaa gaagggttgc gaccgcacct tttcctttat
    78301 ccaagcgcgc ttcgataacc gtaccgattg cacgcactgt tgggtctgcc ttgagttctt
    78361 ggatttcagc tacaagaagg actgtttcca acaattcttc gatattttgg ttgaatttag
    78421 ctgagatttc aacaaattca gaatctccac cccaagcagt tgacataact ccatgctctg
    78481 ccaattcacc gataacgcgt tctgggttag cacctggttt atcaatcttg ttaatggcta
    78541 cgatgattgg aacgttggcc gcttttgagt ggttaatggc ttcgatagtc tgaggcataa
    78601 ccccgtcatc tgccgctacg accaagatcg taatatcggt aacagaagca ccacgcgcac
    78661 gcattgatgt aaaggccgcg tgtcctggtg tatcaaggaa ggtaatcttc ttaccatttt
    78721 ccacgatttg gtaggcaccg atatgctgag taataccacc tgcttcacct gtcgcaacac
    78781 gtgagttacg aagagtatcc aaaagggttg ttttaccgtg gtcaacgtgt cccatgatag
    78841 taacaactgg tggacgctca accaattcat cttcattgag ataaccatct tcgacaaaga
    78901 aacgttcgat gtcagcatta tccacttcaa ccttttgttt ggcttcgata ccgtaatcca
    78961 ccatgaggag ttcaattgtt tccccatcca aggattggtt ttgtgtggcc atgacaccca
    79021 tcatgaaaag tttcttaacg atttcagctg gttcacgttt gatacgtttt gcgatttccg
    79081 caacggtcat accatctgta tattcaaatt ctgttggcaa ttcatggaat ttacgctccg
    79141 taacaggttt tggagtctga ttacggttgt tcttgttatt gccttttttg ttctttttgt
    79201 tgttattcca gttactattc ttttgatttc tcacttgatt ttgactactt cgattctttt
    79261 gttgttttct aggaccatct tcttcatgat cataatcgtc acgatttttg tctggtcgag
    79321 cttgtttttt acgacgtgta tccactgcag gttctttttt ctcagggacg acttcaacca
    79381 ctgcttgaac ttgctgtact tgttcagcta acttagccgc ttcttcaaag atttcctctg
    79441 gttccttgcg tttgttagct tgagccaagg cttctttagc agcctgatac tgcttgaagc
    79501 gttcctcact tgaacgagcg tactctgcat tttgctctgc ttttagggct gctgcacggg
    79561 ctttaaagtc aatacgtgga gccgcttgat ttgaacgttt atcctcttgc tgacggcgct
    79621 catttctacg tttttgctga ccttgctgct tcttagcttg gtcattaaag cgacgattgt
    79681 cgcggttgct ttgaccttgt tttccaccat tacggccgtc gtttttctga cggtttccgt
    79741 tttgttgttg gtcacggtta ttgcccttat tttgcttgcg tcgctctgcc tgctctttag
    79801 cacgtgcttc acgctcagcc ttgaaattac gactttgcgg tttagccgct actttttctg
    79861 ttttcggagc gactggctca gctggttttg cctcttcctt ggctacagct ggttttactg
    79921 gttcagactt ttcggctttc ttttctgcac ttgcttttgg ggctgcaggc ttaaagctgg
    79981 cagcaatttt tgcagcgaca gcttcttcca cacttgatga gtggcttttc acatccaagc
    80041 ccaactcttt tgcacgcgct acaacttctt tactttcttt tccaagttct tttgcgattt
    80101 cgtacaatct tttcttagac aaatcatgtc ctcctcttct attccataag agacctcatt
    80161 ttctttgtaa atccagcatc tgttacagcc aaaacctttc tcgatttccc gactgctatg
    80221 cttaattcca gtgttgaaaa cacggttaca atttctactt gataataatg acttttatct
    80281 tgaatcttct tggtcagatt gggtccagca tcatgagcta gaaagaccaa cttggccttg
    80341 ccgtcttgaa tggccttgac caccaattct tcacccgata tgatgcgccc tgctcgctga
    80401 gcaagcccca agagattact tatcttttgc ttattcaagt cccaactctc ttcttttcac
    80461 tttgtgatcc acataagcga tcaactcgtc ataaaagctt tcttccactt ccatgctaaa
    80521 gctgcggtta aagaccttct tctttttcgc ctctagggct tctgcattgt ctagtttgat
    80581 ataagcgccg cggccattgg ccttgcccgt aggatcaata aagacttgtc cttccttgtt
    80641 cttgacaatg cggagcaaat cacgcttatc aatcacttcg ttagacacaa cagacttgcg
    80701 caaagggatt tttcttgttt tcatctttcc ctcctctagc agcttttatt cttctacagt
    80761 atcgttttct acttccaact ctactgaagc agcgtcttcc atggcttcaa attcgctagc
    80821 agacttgata tcgatacggt aaccagtcaa gtgagccgcc aagcgcacgt tttgtccacg
    80881 acgaccaatg gcaagagaaa gcttgttatc tggaacaacc accaaggcac gtttgctgtc
    80941 gctttcatca aagataactt ggtcaacctc agcaggagcg atggcattgt agataaattc
    81001 agctggatct gctacccact cgataacatc gatattttct tcgattggta ccatgcggtc
    81061 atttttagca tcgtaacgag ctgggtggaa tttgctagta atcttcttga tattagcacc
    81121 accacgtcca acgattgtac cgatagcatc cacgtttgga ttgtggctac gaacagcaac
    81181 cttcgtacgg tcacctgctt cacgagccac gctcatgatt tcaacagttc catcataaac
    81241 ttctggaatt tcttgctcca tcaaacgttt gatcatttct ggatggctac ggctaacaaa
    81301 gacgttcaca ccacgagggt tgtcttcaac cttgtaaaca taaacttcga tacgatcatg
    81361 agaagcaaaa acttctccag gaatttggtc ttgttttgac aattgggctt cgatgctacc
    81421 aaggttgaca tagataaagc ggttgtcaaa gcgttctact gtaccagaca tgatttcttg
    81481 ctcatgttct ttgtaagtat tgtaagtgat ggcacgtgtt tgcttgcgca ttttttccat
    81541 gatggtttgt ttggcagatt gggctgctac acgaccaaac tcagctggtg cttcttcaaa
    81601 cttgattttg tctccaagtt cataagctga attaatggca agagcatctt tcaagctgat
    81661 ttccaaacgg ctatcaaata cttcatcaac aacttcacgg acagtataaa ctgtaaagtc
    81721 acctgttttt tcgttgaagt caatagctac gctgtctgac tgaccatagc gtctgcgata
    81781 agcggaacga agcgactcta ctactgcgtc gatgatatct tcttttttga ttcccttgtc
    81841 ttcttccaaa atgcggaagg cctctagcat ttctttactc atgttttctt cacttttgaa
    81901 tcctcaaaag ctatcctttc tttttctata atttaactgc taaacgtgct tttgatacta
    81961 aactgtatgg aatttggacg gttttcttac gcgtcttgtc catatattcc atagtcaact
    82021 cgtcctcttc gaaggccaac aaggttcctt caaagacctt ttgcttatcg atggcttggt
    82081 agagcccgac atggatgtat tttccaaccg ctccagcgac ggcatccttg gttttcaaag
    82141 gacgttccaa acctggactg gtaatttcta ggaaatattg ttctgggaag ggatctggct
    82201 tgatggtgtc taggacagga ctgatcattt ctgtcaagtc tgccgtgtcg ttcaaggtaa
    82261 ttccttcggg tttatctaca aaaatactga gaatcatgtc actgccaatc tttccatact
    82321 cgatatccac gagttcaaaa ggagcttcta tgacaggttc tacaacttct ctgactaatt
    82381 ctacgattgt tgcgattgcg tccacctcct cataagcaag aggcgaagat atttccccgc
    82441 ctcacttttc atattcttac tatcagtata gcacgtttgc caacttatgt aaagcaaaag
    82501 cacttgtaca gcctaatttt aggctatctc ttaaaattct gcctcaactc ggtagataac
    82561 ttgccccttg tttgagaatt tttgctcgta ttctgtcatg acattgcctt caaaatcact
    82621 ggcatgcaaa tctagccaga caccattgag tttcatgcca tattgagaaa agctcactaa
    82681 actgtactca aacaagccac ggttatccgt cttgaaatga atttctccat tttcaggcaa
    82741 gatacgtttg aaggtatcca aaaaggtctt gtaggtcaaa cgacgctttt catggcgttt
    82801 tttcggccat ggatctgaaa agttcagata caagcgatca atctcaccgt cttcaaagta
    82861 gtcagtcaag tcagaaccat ctacccacaa gagcttgatg ttaggcactc caacttcaag
    82921 caccttgtcc aaagcgtagc tcaaaacaga cttttgaata tcaatcccga tatagttgat
    82981 gtcagggttt tgcttggcca tacctgaaac aaaggcaccc tttccacttc caacttccac
    83041 atgaatggga ttatcattgc caaacaagtc ccgccatttt gccttggctt ccaagggatt
    83101 gaggaccaca tactggggat ttgcctctag taattctgtt gcccctttac gatttctaac
    83161 tctcatcttc tctttccata cttgtctcgg aaatgacgca aaccatgaat ctcccgattg
    83221 acattttcta aatcttggtt catataatac ttggaaatct gactcaaata agacaattga
    83281 ccataccaat acaatttact taataccgtt tgattgtact tgtaaccgta gtaggtcaac
    83341 cattccttcc actgatgttc tgaaatataa tggcagagca tatgggccac atcaaacatg
    83401 cgatcggtca agcgaaccga atcccaatct actaaataaa tcaagccact atctgtctca
    83461 atccaattac tatgtcgtac atctccatgg acaatggtcg catggtcctc tctaaatcct
    83521 ggaatagtct gacgtaaatc agccatcact tcactgataa aatgattttt acgcaaagca
    83581 tctggagccg tttcttgcca agactgtagt aaatctacag gtgtttccat ggcatagccc
    83641 aaacgactca attgtgtcat caacggacgt gagcgatgaa gacgggttaa aatattgacg
    83701 atttgcttac gattcatatc atagggggtc aatatcttgc ctgtcaacca ttcttgagca
    83761 cacatatcac gcccatctgc caaacgacga ctccataata attgtggagc aatttgttct
    83821 ctagctagac caggtaggat tggagaggtg ttcattttta caaagatgcg cttcccatca
    83881 ggatagctac ccatataagc cttgccactt ttcccaggta tgggagtcag tgttagctca
    83941 ttatcaccca aatccatttc tttcctccgt ataaagtttc cttactattc tactagtttt
    84001 tggcctattc gtcaaccact ctaacccgat tctcaaagaa aagcctctgg agtggtttgg
    84061 gttatcatta tagaaagaaa aaggtaagca caatctccta cttacctttt catgattttt
    84121 ataaataata taagagtagc caactgttgt aaagcatatg gactagagta gaaacccata
    84181 agttttggct ctttttataa gcaaggccca gcaacaagcc cccaagtaga taaaaaataa
    84241 acgaagggac attagaaggt ccatgcatga aagaaaagag agaggaagtt agcacaagcc
    84301 ctaaccaaga attgtcaaaa accgcacctt gaagaagtcc tctgaaaatg agttcctcct
    84361 ggatggggcc aaaaactgag gtagtcaaaa tcaaagacag ggaaattcct ctgctgactt
    84421 ccgccaagtg ttggacccct gagccagaag aaacagcgaa gaaatgaata taaaccagcg
    84481 tctcaagtac acttagaaga aagattgcaa tgaaaagcaa aagttgtttc ttgcttaaca
    84541 tcccaaaaga aatcatttca aactttctag cataagcaac actcagcgag gttacaagaa
    84601 gacttacaag aatcaatgca gattcatttt gaaaaaaatc cccatggtta atcgtataag
    84661 gaactataat gacaattatt agtactaaaa atccaaaaca caaggcatga aatttatcaa
    84721 aaaactccat aaaattatcc tcctcaacaa acagacttcc tacacgtcat tctttagttc
    84781 tagcctttcc aaaacaaacc attttatact cttcgaaaat caaattcaaa ccacgtcaac
    84841 gtcgccttgc cgtactcaag tacagcctgc ggctagtttc ctagtttgct ctttgatttt
    84901 cattgagtat tagtaaccaa aatccgacca catagccagc ccctatgaat atagccatta
    84961 aagctagcat ggaatttagg aaattaaaaa ccaccgcaga tacaaaggtt agcacaaaaa
    85021 cattaaaagc aatggtgtca gaagccaaga ctagaatata gggtgtcaac cgatctaaag
    85081 ttttggaatc taggaaaaat aagtgtttat acatgatgac ctcctctatg gctgaaaagc
    85141 aagccttttg tttttttacc ccaagaccct atgtagaaaa gtgagcaaaa acgggaaggt
    85201 cgctacaata ttattgatca catgcaccgc ataggatgga taaatgctct tggtatagcg
    85261 ggtcaaacca gcaaagatga ttccaactgt tgcaaagacg aagatatcta acagactagg
    85321 caggcttgaa aaatgaggga gagcaaataa aatagaagga agaagcaaat caagaccaaa
    85381 tcgcgaatgc ttaaagaaag catgttgcag taatcctcta tagattaact cttccatcag
    85441 tggaaccaga aagaacaggg ctatataaat acctagctct gcaaagttag tcccactata
    85501 accaatcaat acagcccaac cttccgcagt tgactgaaca tgtttagctg tctgaacgtt
    85561 aaaagagatc tggaacacta ccactaatac tgtcaaaatc gaataccaaa gccatttttt
    85621 tcttggaatg cggaagagat aaccatggcc tgtcttaaca agaaccacaa tcatgactcc
    85681 aataaaaagt aaactcaaga tattttgaat ccagacgaaa ttaccaatct gggaagaaaa
    85741 ttgccaataa ttttggacga taagcgtcag ctgagaaaga ccaaatacga aaaataagta
    85801 agagaagact gcacttattt tgaatagaag ttgatacttt ttcatagaaa tcctccctac
    85861 tatgacctca ccttgtcagg ctctactgct gtaagattaa gaagacagtt tgtttttttt
    85921 aaggctaacc tgactactag ataatagata cattaaggca ttaaagacaa tgaaaatatg
    85981 tccatagaat aaaatcaacc tcgcatccaa accaagataa agtttgatta tcaaaaagat
    86041 gagcaaaaga atttgaaacc ataaggtttt tccaaaaata aatttaaagc gatttcgaat
    86101 atctacttcc ttgattttta ccgccacccc tttattagca agaaggaaaa ctcctgcttc
    86161 aaacaaacca ctgtaaagaa caagccaccc aatagatacg atagagattt gtaaaaatgt
    86221 ccctaaaaga atatccaaca cactactcaa gaaaataaca aaaaataatc tgtatttcat
    86281 attaaatacc tccattcatt tatttcacta acaatttaat agagccttct actcaaatat
    86341 cctgtcagaa aaggatagaa agctactttt tataatactt caagccccac atgagcagaa
    86401 gcgtgataaa caagcagaga atacacctat ataaacgatt agttgttgat agaattctgt
    86461 ttctgaaata cctctataca aacaaatgac aaacataaaa tctgccaagc cgataaacat
    86521 aagttgattg gttctaggac taaccaaatc atcatcttca aactctctta atctcatttc
    86581 cctagtaaga taaacagtaa ccaaaataga agtcaagtta ataaccacta aaagaaattg
    86641 gaaaactgac gaaatagaaa tagataagta gaaacaagca aaggcaactg acccaggaac
    86701 aatctcacaa agaatatgat tctttttaat caagaaaatc tttcatttct tttctttctt
    86761 tttaattaaa gaaaaataga tcataaccgc aatcatatag actatggtat aaaatagctg
    86821 ataccaagca ctctccctaa gcggatatag aaagatggac atgattagat acagaacgaa
    86881 aataatcagt atttttttct tcataagatt tcctcctaaa tgtgcgattt atcttagttg
    86941 agcaagaaca tttacactgc tagtatagca cttattttga ccttggatca ctcaaatcat
    87001 aaatggtcat caaaacctct tgaattgtaa aaattaaaaa agcaagcatg aaaaacatac
    87061 tttcctcttt atattgtatt gataccaact tgtttgtaga cttttcatcc tgctatcaca
    87121 tatcattttg acaggcgaaa caatattaaa gaaactcccc tgtaaattaa gctagcaaat
    87181 acaggggaga aatttatttt ttagggggta ctatctgtat cctttttggg aaattttgaa
    87241 aatatttttc taattaaatt atccatataa ggaccaaata taccaactac taaaccaata
    87301 ataaaacttt taaaatccat aattaccacc aacatgttgc tgcataggct acacctccaa
    87361 gtatagctcc acccgcagca ccagttgctg caccttgcca tgttcctgtt ttaatgccta
    87421 gttgaagacc tcttgctgct gctcctccaa cacctgcttt ggcaaaatct ccccaattgc
    87481 atccgccacc ttcaacgcaa gcaagcattt cagtatccat aacagaaaat tgtgacatca
    87541 tttttgtatt catatagtat gtcacttttc agttacggaa caagtttaat ataaaaatta
    87601 tcaaaaaaac ataggcaata aagagaaaaa ttaatttatt atagattaga aataatatga
    87661 caaaacaatt caatgatgtt aattcaatag tcttttgttt tttatcggag atacttatgg
    87721 atagataaat aagataggtt tgaaaagcga agagaataat aaagaatata gccttcataa
    87781 aatttagctt tcatttttat gatgtagcgg tataggctaa atatccacaa accactgctc
    87841 ctccaattcc tcctattgca gcgccccatg gtcctagaag tctcctatat ttcactccac
    87901 ccgctgcaca acctaaagca gcaactacag ctgctcctcc ggaattacct ccataaacct
    87961 cactcagcat tgtttcattt atattacaat aagtattcat acaagtctcc ttttattaaa
    88021 atccacccgt tgcccctgtt actcctgccc aaagatccac accaaattta gctcctatgt
    88081 atccacatgc tcccataaat ggtgctccaa caccactcgc agcacaaata gctgtcccta
    88141 gcccccagcc accaaaagca gcaccaccac cttctaagac attagtttgc caattattct
    88201 tgcctccttc aatactagat aacatagtta tatccatttc atgaaattgt tccataattt
    88261 ttgtatccat gacaaatact cttttttatt tttaattttt gtcttgttgt aactttgaca
    88321 agtttagtat atcatcgttt tttaaaattt ttcatccaga tcttgaatag tcatcgaaac
    88381 gtcttgaatt agcttttcat ttgaaaccac ctctaaattt tttaaaaaaa gataatttct
    88441 aattattttt taccattcag gaagtttcaa tgactattca agatttaata aaatatgaac
    88501 ttatttttat ggcataatat acctatctac tatatgaaag gaattgccaa tgacttctta
    88561 taaacgtaca tttgttcctc aaatagatgc gagagactgc ggtgttgctg ccttagcctc
    88621 gattgctaaa ttctatggtt cagatttttc tctagctcac ttgagagaac ttgcaaagac
    88681 caataaagaa gggacgactg ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga
    88741 aacaagacct gttcaagcag ataaaacgct ctttgacatg agtgatgtcc cctatccatt
    88801 tatcgttcac gttaacaaag aaggaaaact ccaacattac tatgttgtct atcaaacaaa
    88861 gaaagactat ctgattattg gtgatcctga cccttctgta aaaatcacta aaatgtcaaa
    88921 agaacgcttt ttctctgaat ggactggagt agctattttt ctagctccca aacccagcta
    88981 tcaaccccat aaagataaaa agaatggtct actaagcttc cttcctctga ttttcaaaca
    89041 aaaatctctc attgcttaca ttgttctctc aagcttattg gtcactatta tcaatatcgg
    89101 tggttcttat tatctccaag gaatcttaga tgaatacatc ccaaatcaga tgaaatcaac
    89161 tttaggaatc atctcagttg gtctggttat cacctatatc ctccaacaag tcatgagctt
    89221 ctccagagat taagcattga tgtgatttta tcctatattc gccatatttt tgaacttccc
    89281 atgtctttct ttgcgacacg tcgtacagga gaaatcattt cacggttcac agatgctaac
    89341 tctattatag atgccttggc ttctaccatt ctttctcttt ttctggatgt ttctattctg
    89401 attcttgtag ggggagtctt gctggcacaa aaccctaatc tcttccttct ttctcttatt
    89461 tccattccta tatacatgtt catcatcttt tcttttatga aacctttcga aaaaatgaac
    89521 catgatgtca tgcaaagtaa ttctatggtt agctctgcca ttatcaaaga tatcaacggg
    89581 attgaaacta taaagtcgct cacgagtgaa gaaaatcgct atcaaaatat agacagcgaa
    89641 tttgtagatt atttggaaaa atcctttaag ctcagtaaat attctatttt acaaacgagt
    89701 ttaaagcagg gaacaaaatt agttctgaat atccttatcc tatggtttgg cgctcaatta
    89761 gtcatgtcaa gtaaaatttc tatcggtcag ctgattacct ttaacacact tttttcttac
    89821 tttacaactc ctatggaaaa tattatcaac ctccaaacca aactccaatc tgcgaagatc
    89881 gctaataacc gtttgaacga agtctatcta gtcgaatctg aatttcaagt tcaagaaaac
    89941 cctgttcatt cacatttttt gatgggcgat attgaatttg atgacctttc ttataagtat
    90001 ggttttggac gagatacctt aacagatatt aatctcacga ttaaacaagg agataaggtt
    90061 agcctagttg gagttagtgg ttctggtaaa acaactttag ccaaaatgat tgtcaatttc
    90121 tttgaaccct acaaagggca tatttccatc aatcatcagg atattaaaaa cattgataaa
    90181 aaagtcttgc gccgtcatat taattaccta ccccaacaag cctatatctt taatggctct
    90241 attttggaaa acttaacctt gggcggtaat catatgatta gtcaagaaga tattctaaaa
    90301 gcttgtgaag tagctgaaat ccgtcaagac attgaaagaa tgcctatggg ctatcaaact
    90361 cagctctctg atggagctgg tctatcagga ggacagaagc aacggatcgc cctcgctcgt
    90421 gctcttttaa ctaaatctcc tgttttaata ctagatgaag ctactagcgg tcttgatgtc
    90481 ttgactgaga aaaaggttat agataatctt atgtccctaa ctgataaaac cattctcttt
    90541 gtagcccatc gtctcagtat agccgaacga actaaccgtg tcattgttct tgaccagggg
    90601 aaaatcattg aagttggtag tcaccaagag ttaatgcagg cgcaaggctt ctaccatcat
    90661 ctattcaata aataaggaga atgtcatgaa tcctaatctt tttagaagcg tcgagtttta
    90721 tcagagacgt taccataact atgcgacagt gttaattata cctctttcat tactgtttac
    90781 tttcatcttg attttctccc ttgttgccac aaaagaaatt actgttactt cccaaggaga
    90841 aatcgcccct acaagtgtca ttgcatctat tcagtcgacc agtgataatc ctatccttgc
    90901 taatcattta gtggcaaatc aagtagttga gaaaggtgac ttactcatca aatactctga
    90961 aacaatggaa gagagtcaga aaactgcctt agaaactcaa ttacaaaggc ttgagaagca
    91021 aaaagaagga cttggaatct tgaaacaaag cttagaaaaa gcgactgatc ttttttctag
    91081 cgaggatgag tttggctacc ataatacttt tatgaatttt actaaacaat cccatgatat
    91141 tgaactgggt atctcaaaga ctaacactga agtttcaaat caagctaatc ttaccaatag
    91201 cagttcatca gccatcgaac aagaaattac aaaagttcaa caacaaattg gagaatatca
    91261 agagctgaga gatgctatcg taaataaaag agctcgctta ccaactggca atccgcacca
    91321 gtcaatttta aatcgttatc ttatagcctc tcaagaacaa acacaaggaa cggcagagga
    91381 gccattttta tctcaaatta atcaaagtat tgcaggtctg gaatcatcta tcgcaagcct
    91441 caaaattcag caagctggca tcggaagtgt agcaacttat gataatagtt tagcaaccaa
    91501 aattgaagta ctccgcactc agtttttaca aacagcctca cagcaacaac taaccgtgga
    91561 gaatcaatta acagaattaa aagtacaact agatcaagcg acacagcgct tagaaaacaa
    91621 taccttaacc gctccaagta aaggtatcgt tcatctgaac agcgaatttg aaggtaaaaa
    91681 tagaattcca actggtacag aaattgctca aatattccct atcatcacag atacaagaga
    91741 agtactaatc acttactacg tatcttctga ctatctacct ctactagata aaggacaaac
    91801 tgtaagatta aaactggaga agattggaaa tcacggcacc accatcatcg gccaacttca
    91861 gacaattgat caaactccta ccagaacaga gcaaggtaat ctctttaaat taaccgctct
    91921 tgcaaaacta tctaatgagg atagtaaact catccaatat ggcttacaag gtcgcgtcac
    91981 tagtgtaact gcaaagaaaa catattttga ttatttcaaa gataaaattt taacccattc
    92041 tgattaattt tcagataaca ctctataact atttattatc ttatcaaaaa ggagaatcat
    92101 aacatggata agaaacaaaa cctaacttca tttcaagaac taacaactac cgaactcaac
    92161 caaattacag gtggaggact gtgggaagat atcttataca gccttaatat aattaagcat
    92221 aacaatacga aaggacttca tcatccaata caactataaa aaataagacc gagtaacaag
    92281 aactctcggt cttatttttt tcatcattct gtaggtatca tagtaagcac ctgacgaaag
    92341 acttgatctt gacaggtagt atttaaactg gcattgggat aactttccac aatcttcata
    92401 acggtataga gaccgacacc tctctcctcc cctttagaac taactccaaa ggagaagatt
    92461 tcagaaatat ctatgccctc ttctttgatg gaattttcga tgatgaaggt ctcctgtgct
    92521 ccacttttta aaaaggcaat tgaaacatga ggttgaccgg cctctgcact cgcttcaata
    92581 gcattatcac aaaggataga cacaatggtt agaaaatcaa gcagtctcat cccctcaacc
    92641 tgaatctctt caggaacttc gacattaaag acaatgtcct tttctctagc ttttataaat
    92701 tttccagcta ggagactttt gagggcacga tcccgaacat tcaccaatcg gcccaggtca
    92761 tatttattgt cctgcaattt tttactagaa tcctttaaga ccaagtcata gacctctttt
    92821 atctgctcca tatcctcctc ttcaataccc agacgtaaac ttgtcaagag gttggtgtag
    92881 tcatggcgaa aactccttac ttccttgtaa agttcctcta tatgccgact atagcgttcc
    92941 atatctctat agcgcaagac ctgctcttgg tccagtctat catggagttt gtccttcaaa
    93001 taggtatcca atttcttgat aacccccata aaaaatagga ggtagaacac taggatgaga
    93061 tggcgaacag tcgttgattg aataccttgc tcatattcaa agtaagacag actttgtatc
    93121 accaaatagt aagcccccat tatccagtta atcttagtca gggacttttg aaaacctgta
    93181 tctagaatct cccttctcaa actagtaaaa tcatagtcca accatttcaa aaaggctaga
    93241 gaaatgaaga aattgaaaat tattatacat aacccagtaa atgagtagcc atcatatact
    93301 tgcccttgtc ccaaaaatgg aagcacaaaa taggagactc ctctataaaa gagattcacc
    93361 aatatcattg gaaagagagc ataaaagaaa aggagttttt taggaagccc tcttaacaat
    93421 aagaaagaca agcctatgcc gtacaagggt tccataaaat aagataggta aacatttcct
    93481 actatatagc taatcattac aaaaacaaag accaacagta tcttcaaaag aaaggcctta
    93541 aaaatcctct cgaaagtaag attaattcca tccaccttaa agaaaatgac aatttctagc
    93601 ccattagtaa taagtgtatg caataatatc caaacaatat tcataaactc tcctagttca
    93661 gtgtaagtta ttaatagcct cagacacttc cctgacctta taacgggcga ttagacaact
    93721 tcctccattg ggaaagaaaa gcagtttttc tttcttatcc aaatgcacca catttgcagg
    93781 attgatgaga aaggagcgat ggcactgcaa aagacgaggt tcctgcttaa aaacctcctc
    93841 taaactcgct gtaaattcca gcctgtctgt cttggtatag agaataacac gatggggtct
    93901 tggggatgtt tcgagatagt aaacctcttt aaaaggatac tggaattggg caaattttga
    93961 tttaaagtaa aagcaatctt ccgccagact tttactatct tgactattgg catagaggag
    94021 ggctgtctcg attcgagatt caaactcctc tgccgaaagg gccttatcaa tatagtccag
    94081 agcagacact tggtagcgaa aggacagggg cataaactcc gagtgagtcg tcacaaagac
    94141 aatcagggca taggggtctc gatcccgaat ctttctagcc acttccagcc ccttcatctc
    94201 ctcatttcga atctcaatat ccaaaaagaa tagctgatgg gcccccttct catgcacctc
    94261 tgccagcagt tggtctggct tgccaaatac ctcaaaagag ctgggagtga tatgatgttc
    94321 cttcaagagt ttctcaatcg tcgtttcaat cctagtctgt tgggaaaaat catcctctaa
    94381 aacaaatatt ctcatcttct tactctccct ctttcaacca tttttgacga atttctctat
    94441 agcgacgtct ggcatacttg acagcgtatt gaccttcttc tccgagaaaa aggattcttt
    94501 cttgaaaatc aatcgatttt aatttatcaa gattaactaa acaatttcga tgacatctca
    94561 tcaaggtttc cccacattgg ttctcaagat tacttaaatt ttgaaccata ttaaaactag
    94621 ctttttctgt aacaatctgt acggtatggg ctttagttgg atgtgtttgg atatagtaga
    94681 tatcgtcgat gtttacttta tagactgttt tctgtgtctg aataatcata tgtttcattg
    94741 gattctcctc ctaagaaaag aataacagaa aaggtctagc ccaagcccac ccaatcctaa
    94801 acagtctttg aaaactccta aaaggattat tttctacaac atcatgatga gcttacaact
    94861 attttatcat aaaattcact cagcgcaatt caagacattt caatgacaat taaagatttg
    94921 aataaaaaaa aagaattaaa agtgataaac taacagtatc aaaacacagt tgccagaagt
    94981 aaaactggca cccagattaa aggaggcatt cccatgacag atacagaccc catcaaaaga
    95041 gctcatactt tgattactga cttaaacaaa gcctaccaag catgcaaaca ggcaagcgct
    95101 gacgacgtcc gctttcagga gcaattaaac tctattcttg gttttctagc caaggctgaa
    95161 acagtggata atcgattctt gattgaattg gaaaaatttt accagacttc cagtcttctc
    95221 atgggactca gcgctcttga tccagatgct ccaactcgcg ccgcttggcg ggcctatgac
    95281 cgcttccact ttgaccaagt caagaccaag ttaatactca atgaaaatca aagagcaaac
    95341 taggaagcta gccgcaagct gtacttgagt acggtaagac gacgctgacg tggtttgaag
    95401 agattttcga agagtataag tctctacgga ccaaccatta tcctgtagta acaaaaaaga
    95461 agctgagaca gactgaactc aacttctttt ttagtgtcgt atcagcaatg ttagtcctgc
    95521 atctgacgtt ttacctgata aggcaaatac aagacttgta aaaccaaacc agctcccagt
    95581 aaggctagaa gggctagttt ttcttgaaag gtaatcaacc caacaactaa ttccacaagt
    95641 aaaacaaaac tggtcaatcc tcgaactacc tcctgtaagc ctttttcctt ttgccccttg
    95701 tccagcggaa agagttgggt caaatactgg tagtcaaagg catgatagag ggccagcaac
    95761 tggaagagca agaggtagtt aaagagaact accactgctg tcgcaatcca agcttgctcg
    95821 ataaaaacct gcgccagtac ggaaagtaag agaagacgaa gactgagagc aaagaggtcg
    95881 ccatttcgca gataagaacg cagatagaga ttttgccaaa tcttcccagg caccttctga
    95941 acagccttta agataaagtc cagataggca cgacgcttaa cgctgtttga aattcccttg
    96001 acctgcgtaa agagggcaaa gaaacgaagc aagacttgct tacgcttgct ttcttgagaa
    96061 ataacatagt cccagtccag tccagtttca gtgaaaaatt tgctggcctt ttgacgaaag
    96121 tggaaatatt ttcctacccc caataaaagc acatagagca gaaaaactgg caagccataa
    96181 cccattgcta aaaataaagg cgcaaataac agcaagaaaa gggtctgtac aaagagccaa
    96241 aagactaggg aaatgccagt ttgacgcttg agatggagct tgatttcctc ttctccaact
    96301 aagagaaaga gcttgtctgg agcctccata taggtggcaa ttcctcccca aagtaaaagt
    96361 aaaacagacg taattcctac aaacaaaagg ataggccaat gattttcagg aaaatgttgt
    96421 aagagttgac tgtactggta ggctagaaag cccaacagga caagcaggaa caagacaaag
    96481 tggtcattga gcacatagcg cagataacca agacactcct tacgaaaggc ctgctttctc
    96541 tttaaaaaca agtctttcat agatcctcct ctttggtcag agccaagtaa atatcattca
    96601 aactagcctc aggcatatca aaggcttcac gtagttgcag gagattgcct ttggcacgca
    96661 cctctccctt gtgaagaatg acaaaggcat cacacatctt ttccgccgaa tccagcacgt
    96721 gggtactcat gagaatagac ttgccctttt gcttctccac ttccaaaagc tgaatcaaat
    96781 cagaaatagc cagcggatca agaccaagga aaggctcatc cacgatgaaa agacttggat
    96841 ccaccacaaa agcacagata atcatgacct tctgcttcat cccttttgaa aaatgaacag
    96901 ggaaccagtc taatttctgt tccaaacgga acatttttaa caagggctct actcgttcga
    96961 aagccacttt ttgctcaata ccgtaagcca tagcaaccgt ttcgatatgc tctctgaggg
    97021 tcaattcctc atacagacta ggcgtctcag gaatgtagcc aatctgcttg cggtagctag
    97081 tcgcatctcc ttccagagtc aggccattga tattgatgga gccactataa ggtgccaaca
    97141 gaccgataat ctcattgatc gtcgttgatt tcccagcacc attgagacca atcaaaccga
    97201 ccaactgccc actttcaaca gtaaaggaca catctttcaa aacaggaaca tgaacatagc
    97261 cacctgtcag gtttttaatt tctaacatat tttctccaaa tctggtataa tgtagctata
    97321 ttatatcaaa attcagtaca gtagaggtag attttatgtc agattgcatt ttttgtaaaa
    97381 tcatcgcagg ggaaattcct gcttcaaaag tatatgaaga tgagcaggtc cttgcctttc
    97441 ttgatatctc tcaagtaaca ctaggacaca ccttggtcgt gccaaaagaa cactatcgca
    97501 atcttttgga gatggatgct acgagcacca gccaactctt tgcccaagta ccaaaagtag
    97561 ctcaaaaagt catgaaagtc actaaggctg ctggtatgaa tatcatttcc aactgtgaag
    97621 aagtcgctgg tcaaacagtt tttcatactc acgttcacct tgtgcctcgc tacagtgctg
    97681 acgatgacct caagattgat tttatcgccc acgaaccaga ctttgacaaa cttgctcaag
    97741 tcgctgaaac catcaaaaac gcttaaggag ttgctatgaa attatccaac ctactgctat
    97801 ttgcaggagc tgcagccgga agttatctgg ttacaaaaaa tcgccaaacc atcacagatg
    97861 aagtcttgaa taccactgac cgcgttcaag ctatcaagga cgatgtggat attatccaaa
    97921 atagcctgca aatcatcgac cagcaaaaag aacttatcaa ggaataccaa gaagacttga
    97981 cttacaagtt taaggtcttg gaaaaggata tccagactag actagctgtg ataaaagaaa
    98041 tgcagggaac tgaagataag taaaaagagc cccccggctc ttttttaaaa cgtaaacaag
    98101 ttatagtgaa ttgaatttag aatagcacac catagtttct aaagcattgt tagagattac
    98161 tttaaaatcc tcttatcaat ttgttcatat tctatttcaa tctactatat atatcccatc
    98221 aactatgcat cataatttag gtaattcata ctcaataaaa atcaaaaagc aaactagaaa
    98281 gctaggcaca gactgctcaa aacaccgttt taaggttgtg gatagaactg acgaagtcag
    98341 ctcaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca tacccatgac
    98401 aagccgacgc tgacgtggtt tgaagaaatt tttgaagagt atcattcacc atttcacaac
    98461 taaatcgaag actttctgcc gtaatgaaaa cacctgaaac agcttggttt cagctgtccg
    98521 gaaactttaa aacttaggtt caaagtttag gtatggaact tcgaaggagg tcactaccgt
    98581 ccgtcattac ttaggaaagt cttaaaaaat ctataaagta aaaagagccc gacagctctt
    98641 tttgtttata ctcaatgaaa atcaaaaagc aaactaggaa actagccacg ggctgctcaa
    98701 aacactgttt tgaggttgta gatacgactg acgaagtcag tcacatatat acgacaagcc
    98761 gacgctgacg tggtttgaag aaatttttga agagtattat tctccatcaa aggcatcttt
    98821 aatatggtca aagaagcctt ttttctttgg atttactttc aagtcaccag cagccgcgaa
    98881 ttctttcaag gctacttttt ggcggtcgtt caagcctgtc ggtgttacga cattaacagt
    98941 aacgtattgg tcaccaactg caccgccacg aaggctcggt gcccccttac tacgtaggcg
    99001 gaatttctta ccagtctgag ttccctctgg aataaccaat tcaacatcac cgtgaacagt
    99061 tggaatatct actgtatcac caagagccgc ttggacaaag ttgaggttga gattgtagaa
    99121 gatagtcgtt ccttcacgtt caaacttgtc actagcttcc acagaaacta ctacatacaa
    99181 gtcaccataa ggtccaccgt taaagcctgc ttcaccttga ccagcgaggc gaatttgttg
    99241 acctgtttcc acaccagcag ggattttcac atgtacgcta tgagcttgtt tctcatgacc
    99301 tgttccatga caggttgtac atggatattt gatttctttt cctcgaccgt gacagacatc
    99361 acaggttact tggcgacgca tcataccaag aggagtctgc gtatcgacgt taatgacacc
    99421 agcgccatga cagcgtccac aagtgactgg acttgtccct ggcttagcac cagatccatt
    99481 acatgtacga cagccagctt cacgatgata cttaacttcc ttctcagttc cgaagatagc
    99541 ttcttcaaag gtcaaattga cacgatactg gagatcatct ccttggcgag gagcgtttgg
    99601 attgcgcgaa gaaccgcctc cgccgaagaa acttgagaaa atatcctcaa aaccaccgaa
    99661 gccacctgcc ccattgaaac caccgaaacc accagctcca ccaaaaccac cattggcgcc
    99721 tgcagcacca tactggtcat aggcagcacg tttttggtcg tcactcaaag tctcataggc
    99781 ttcttgaact tccttgtact tgtcctcagc accaggctcc ttgttgatat ctgggtgata
    99841 ttttttggaa agcttacgat aagccttttt gatttcgtct gccgaagcgt ttttggatac
    99901 ccccagacga tcataaaatt cagtattgtt cataattcaa gatacaaagg gcgtcaaacg
    99961 gacacagcca tctaggagtt ttgacgacgg acgcttacgt cctagaaaaa actatctttt
   100021 tggcacagtc cgtagcccgt gttcagttac gaacaccctt attcctttct attgatgttc
   100081 tgaatcgaac caccatttag gtcgggttca attcctttct tttatattta gtaagaaatt
   100141 ctgaaacccg tgttcagtta cgaacactct ttgttccttt ctattgatga gacaaaaccc
   100201 aaacaaatga gattccgtcc ctttttatcg aaaaacagag gctgggttgc aacctctgca
   100261 aataagtaaa ttaactttat tttgatttta aatatcctat aagtacagaa atatttatat
   100321 atttttgtct cttcttagta tttgcctata taattccaat tgatcataag aaatacaact
   100381 actgtccaaa tcataccaat tatgaacggt attacaaatt tatatgtttg tatttctaat
   100441 gatatcatag ctgataccat cgccgataca aatgcagaca acaatactga ggtaacaaaa
   100501 ttccttaccg cttcatcatt tttgatacaa ctatcatgtt cagctaatat aatttctcta
   100561 tatctagcta aatattctat tggaatatta tcaataaaat cttttgatgt tctatagtta
   100621 tcagcttgat tacaaaaatc attataaact tttcgtgtat tttttagata ctcttcatcc
   100681 aatacactca tcttactttt ccgtaaactc tccgtctacg acgtcatcgc ctgcgtttcc
   100741 tgttgcttgt gcgccttctg ctccttcttg agcttgttgc gctgctgcgg cttgttcgta
   100801 gagtttaaca gcaagtcctt gagctttttc gttcaatgct tcaagttttg ctttcatgtc
   100861 gtccaagttg ttgtcttctt gagctttctt aaggtcatca agggcagctt gggcagcgtc
   100921 acgttctgcg tcgaagcctt taccttcagt ttccttgatt gtcttttcag tcgcaaagat
   100981 tgcttggtct acttcattac gaaggtctac ttcttcttta cgtttcttat cggcttcagc
   101041 gtttgcttct gcatctttca tcatgcggtc gatttcttcg tcagtcaaac ctgagttcga
   101101 ttggatgaca atagtttgtt ctttttgagt tccaaggtct ttggccttaa cagacacgat
   101161 accgttcttg tcgatgtcaa atgttacttc gatttgagga attccacgag gtgcagctgg
   101221 gatatcagtc aattggaagc gtccaagagt cttgttatct gctgccattg ggcgttcacc
   101281 ttgaagaacg tggatatcaa cggctggttg gttgtctgct gctgttgaga agacttgtga
   101341 tttagatgtt gggattgtag tgttgcgatc gataagtttt gtaaatactc cacccattgt
   101401 ttcgatacca agtgacaatg gcgttacatc aagaaggaca acgtccttga catcaccagt
   101461 aatcacacca ccttggatag ccgcacccat agcaactact tcatcagggt ttactgattt
   101521 gtttggttct ttaccagttt cagctttaac agcttcaaca acggcaggga tacgagttga
   101581 accaccaaca aggataactt cgtcgatttc tgacaagctc aaacctgcat ctgaaagggc
   101641 ttgacgaact ggaacttttg tacgttcaac aaggtcacga gtcaaatcat caaatttcgc
   101701 acgagtcaaa gtcatttcca agtgaagagg tccagcctca cctgcagtga taaatggcaa
   101761 gctgatttgt gttgaagtta caccagaaag gtctttcttc gctttttcag ccgcatcttt
   101821 caaacgttgc attgccatct tgtcagtaga caagtcgata ccgttttctt tcttgaattc
   101881 tgctaccaag tggtcaatga ttttttggtc aaagtcgtca ccaccaagtt tgttgtcccc
   101941 tgcagttgac aatacgtcga agacaccgtc acccaattca aggatagaga cgtcgaatgt
   102001 accaccacca aggtcaaata ccaagatttt ttcttctttg tcagtcttgt ccaaaccata
   102061 agcaagagct gctgcagttg gttcgttaac aatacgttct acttcaagac cagcaatttt
   102121 accagcgtct tttgttgctt gacgttgagc gtcgttgaag taagccggaa ctgtgataac
   102181 agctttggtt actttctcac caaggtagtc ttcagcgtag cctttcaagt attgaaggat
   102241 catagctgag atttcttgtg gagtgtattc ttttccattt gcagaaactt tttcagaagt
   102301 tcccatctta gatttgatag agataactgt atctgggttt gtaactgctt gacgttttgc
   102361 agcatcacca acgatgattt ctccgttttt gaatgagact acagatggag ttgtgcggtt
   102421 tccttctggg tttgcgatga ttttgctttc agttccttca agaactgcaa ctgctgagtt
   102481 tgttgtacct aagtcaatac cgataatttt agacatgtgt ttttctcctt gttagttaat
   102541 tttctatttt tctttttgat actcttctta agtggcgacg ccgtcagagc ttgacttcgt
   102601 caatctcttt gactaaactt tgagcctaag gtctcaaaat ttgcgcaaat agcaccacgg
   102661 cgaagagtat cgtctttggt tcgcttcgct cactattaca aagccaaaca tattttatct
   102721 ttcttcatag tttattgtcg tttcggacaa gttttctatt atgtaaattg cgacacgagg
   102781 agtcgaaatc gattttattt cgacgacgag ttagtaagga agctaggcaa acgtcatagc
   102841 gattgccgtt ttctgacgag ttgctttagc taccgtcaga attgccgaat cgaacacgcc
   102901 ctaagctctg agtaaaaaag atagattttc ttgtgttcat cgaacacttc gtcaatctcc
   102961 tatttttact gcgagctttt tacgagcttt gtatcttagt tatacaccac taccattgct
   103021 gggcgtagga tgcggtcatg gagtttgtag cctttttgaa agacttgggc gatggtatct
   103081 actgggtgtt catcgtctgc tgggagagtt tggatggcca tatggtagtt atggtcaaat
   103141 tcgccatctg ctgcgatttc ttcaattcct tcttctttca aagcgtgaat caagctttct
   103201 tgcaccatcg ccaagccctt cttcacatca tctgtcaaac cttcaactgc aagtgcacgc
   103261 tcaaggttgt caagagatgg taagattgct tttgccaagt cctggctacg ataacgttgc
   103321 aagttttgac gttcttcatt ggcacggcgt tggatatttt gcatttctgc atgagcgcga
   103381 agatatttgt tttcgaactc atctgcacgt tcatttgcca agtccaactc agacttttca
   103441 ggagttgttt cttcagctgt ttccacaact tcctcttctt gaacttcttc tacttcttca
   103501 ttttttatat cttgggccat gttcgcctcc tttaatgatt tcaatcttaa tgtacttcgt
   103561 aatgattact gctgaggtag cggtaaaaat ctgtcaactt catggtcaaa acacggttga
   103621 ccacattgac ttgattgatt agctgttggt aatccagatt aactggaccg ataatggcta
   103681 gaattccaac tccccgataa ggaatgagga acttactact aatcaccgct aggtcagcta
   103741 aacaggactc ttgaccgtct gcaacacgaa cattttgcat ctgatcctca cgcaacccct
   103801 cacgaatctc caaggccacc ttttgcggtt ggtcaaagaa ctgataggct tctagattgg
   103861 caaaattcaa gagattgacc ttgcccgcca tcacaatgtt ttcgttgaac atttccttaa
   103921 agatgtgttc aaagagatcg atgacattat ccgttgttgt aaagtaacgc tggataatct
   103981 gcggaatctc cgtccgaatc ttgtagtgaa tatctaaaac ggtgtgaccg aggaaacgtt
   104041 cctgaatgat gctcttcagt ttcagcaaat cctcctgcaa gaagttcctt ggaatcagaa
   104101 actgactagt aaccgttcgc gactcgtcta gggtaaatac cgccaaggct gtatgttgcc
   104161 ccaaaacaac gatatcaaag gctgtcaaac gttgcctgct cggctcaaca tccagtgcca
   104221 ctaccgtaca gccactcagg tctgttagca agttagcagc ctcttgcaga atatcctcca
   104281 atttgaagaa ttcctgatca aaggctttga caatctcata tacctcattt tcagccagtc
   104341 ggtcaaaatc cagtgagtgt ttcacatagt actgaaaacc agcaacactt ggcatccgac
   104401 cgcttgaagt atgagccttc tcaagcaacc cttgtttttc tagttccgcc atgtcattac
   104461 gaatggttgc actgctagag ttaatagact cttgcaaggc ttttgatccg acaggttcgt
   104521 gcgttttggt aaagatgtca ataatcagat ttaaaatatc ctgctgacgc tctgttacca
   104581 tctcatcact cctctctgtc tgatcaatta gcactcaatg catccaagtg ctaactcatg
   104641 attctattat acacccttag aagagaatgt caagacaaaa actcaaaaaa ttagcactct
   104701 tttatcaaga gtgctaaaaa tcaatctgaa gacctagaac cttgctattc atctactcgg
   104761 tatttccttt ttagtctgaa ataaccatga attagataag aaatcagaaa agcatataaa
   104821 acaaaaataa gaaagaaaga catagaaaga tcttctctaa acgaactcat acaaacaaca
   104881 agaccacctg agaaagcaac tgtacaggaa cgaagtctag atcgcataac ttcccatttg
   104941 agccccttac tcatatagac ttgaacctct ggaagtaaat cagaagacga tttacgaaga
   105001 atcgaacaag aacctgctcc tatcaattcc caacctctat ctctaaaatc ttgcagttca
   105061 tgcttatact ttttaagaaa tctagaatca tagatacggt agatgacatc gtctggttga
   105121 ccttgctcaa aatagaacaa accaaaacga ctagttctat acctccaacc tttcaaatgc
   105181 atctcatgta aatattcttc ttccttgtcc aaatcaggaa tagtgaaaat ccgaaattct
   105241 actctgctat tcattgtctt accccaaaat tagaaaacat gcctggcgtt atttattaga
   105301 taattctttc cacttttgac tcaatctcca aaaaatataa gaaatctgaa tcgcaaaaac
   105361 tatcaataaa acccaatcta ttatgaaaat caaaaatact ccccaactga aagaactacc
   105421 tccagtgaca aactttgaga aaaacggtag tagagctaaa aagagaagca aaataggaag
   105481 catccgcatt gttaaaatcc gtttggcata aaaaatcttt atttaaacga aaatattatg
   105541 gcaaaattta cgccagtttt tgaacggctg atgtagatat tttatacttt caaaatgttt
   105601 aaatgtgatt atttattttt gaaaaatagc tcaccagccc gactgaaagt gcttatagaa
   105661 tgataataag tcgcctgccg aaaacagcga aaaatagcgg tgttatgcgg agataatctg
   105721 acgcgatgcg aaagtatatt gcatacttat tttcaacaat ttagcagagt atttttataa
   105781 gtgtgatata atagaagtat aatttgttct gatagtttat tttatggaga agtagatttt
   105841 tagaatgcgg agggttcaat atggttgagt ttataaagtc taagaaagaa atgagtgagg
   105901 aggatattaa agcaaatttc atcactcctg ctattgtatc caaaggatgg aaaaatggtg
   105961 agcatatcgc ttacgaagaa tacttcactg atggtcgaat tgaggttaga ggagataagg
   106021 ctcgtcgtaa agaaggaaaa aaatcagact attcactgta ttaccaattt ggaactcgaa
   106081 ttgcaattgt tgaggcaaag gataataaac acagcgttcg agcaggatta caacaagcta
   106141 ttgaatatgg agagatttta gatgttccat ttgtttattc ttcgaatggt gatggcttta
   106201 ttgaacacga ccgtatcacg agagaagaac gtgagctgga gttagacgaa ttccctactc
   106261 gtgaagaatt attttctcgt atgacgaagg aaaaaggatt gacgtacgaa attacagaag
   106321 ctatctcaac tccatactat acagacgcct tctcaatgaa aacgccacgc tattatcagc
   106381 aaatagctat caaccgtact attgaaacag ttgccagagg acaaaaacga gtaatgtttg
   106441 tgatggcaac aggaacgggg aaaacgttca tggcttttca aattattcat cgccttcgaa
   106501 aagctggttt ggctaaacga gttttattct tagcggatag aaacatctta gtagaccaaa
   106561 cgatggctga agactttaag ccattcgaaa aggtaatgac gaaaattaca ccaaaacttt
   106621 tgactgctcc tgaaaaatta aattcttttg aaatttatct agggctttat cagcaactaa
   106681 ctggtgaaga tggaactgaa acacattatc aaaaatttga caaagacttc tttgatttaa
   106741 tcgtaattga tgaagcgcac cgtggttcag ctaaggaaaa cagtaactgg cgtaagataa
   106801 ttgattattt cagttctgcg acacagattg ggatgaccgc tactcctaaa gaaaccaaga
   106861 atgcttccaa tacggaatac tttggtgagc caatctatac ttatagttta aaacagggaa
   106921 tcgaggatgg ttttttggct ccatatcgtg ttatgagggt taatttagat gtggatgtgg
   106981 atggttatcg tccagaaact ggaaaagttg atgctaacgg acaattaata gaagataggt
   107041 actacagcag gaaagatttt gataaaacca ttgtcattga tgatagaacg caaagagttg
   107101 ccaagtttgt ttctgattat atgaagcaaa acaatgcacg atttgataaa acaattgttt
   107161 tttgtgttga tattgaccat gccgagcgaa tgcgtgctgc acttgtaaaa gagaatctag
   107221 acttagtcca agaagactat cgttatgtca tgcaagtaac tggtgacaac gctgaaggaa
   107281 aagctcaact ggataacttt atggatgtca attctaattt tcccgctatt gtaacaacgt
   107341 ctaaattatt aacgacagga gttaatgcta aaacatgtcg tttgattgtt ttagactcta
   107401 atatccaatc catgactgaa tttaaacaaa ttattggtcg tggcacacgt ctttatcctc
   107461 aaaaggggaa agaatttttt acgattattg attttcgaaa tgttaccaat ttgtttgctg
   107521 accctgattt tgatggtgag ccagtgaagg tgctggaaac aggtgcgaaa acagtcagtg
   107581 gttctacgcc cggtttcgta gatgaggaag gtgacccagt agaaaaatat atcgttacag
   107641 acaagcaggt taccattctt aattctactg ttcaagtatt ggatgaaaac gggaaactga
   107701 ttaccgaaag cctgaccgac tacactcgga agaatatctt aggtagctac gccactttga
   107761 acgattttat cacagtttgg catacggcgg ataaaaagaa gcttatctta gacgaacttt
   107821 ataaaaaagg agtttatcta gatgctattc gagagtcgga gggaatatca gaacaagaaa
   107881 tcgatgattt tgatttactc ctaaaacttg cctatggtca aaaagaatta accaaaacgg
   107941 aacgtatcaa taagctcaaa caaagcggat atttatataa atatagtgag gaagcgcgtg
   108001 ctgttttgga aattttactg aacaaataca tggataaagg tattggagaa ctcgaaagca
   108061 ttgaaacatt aaaacttcca gaatttcaaa tatatggtgg aaccttcaaa atcatcaata
   108121 cttattttgg agataaaaaa cgatatttac aagcaattaa agaattggag caagagctat
   108181 ttacagtagc ttaatgaaag gaaagtatgt caattacatc atttgtaaaa agaattcaag
   108241 atatcactcg aaacgatgct ggtgttaatg gtgatgctca acgtattgag caaatgtctt
   108301 ggttattatt cttaaaaatt tatgatagcc gtgaaatggt ttgggaatta gaagaagacg
   108361 agtatgagtc aattatccca gaggaattaa aatggcgaaa ttgggctcat gctcaaaatg
   108421 gggaacgggt attgacaggc gatgaattac ttgattttgt caataacaag ttattcaaag
   108481 agttgaaaga gcttgaaata acttcaaata tgcctattcg aaaaacgatt gttaaatcag
   108541 cttttgaaga tgcgaacaac tatatgaaaa atggcgtctt gttacgccaa gtcatcaatg
   108601 ttattgatga agttgatttc aatagccctg aagatcgtca ttcgtttaat gatatttacg
   108661 aaaaaattct taaagatatt caaaatgctg ggaactcagg agaattttat acgccacgtg
   108721 cagcgactga ttttattgcc gaagttcttg acccaaaact tggagaatca atggcagacc
   108781 ttgcttgcgg aacaggaggc ttcttgactt cgactctgaa ccgtttaagt agtcaacgta
   108841 aaactagtga agataccaaa aaatataata cagctgtttt tggtattgaa aagaaagcat
   108901 ttcctcatct tttagcagtt acaaatctgt ttcttcacga aattgatgac cctaaaattg
   108961 ttcatggaaa tactttggag aaaaatgttc gtgaatatac ggatgatgaa aaatttgaca
   109021 ttattatgat gaatccacct tttggagggt cagaattaga aacaataaaa aataactttc
   109081 cagcagaatt acggagttct gaaacagctg atttatttat ggctgtcatt atgtatcgtt
   109141 tgaaagaaaa tggtcgtgtt ggagttattt tacctgatgg ttttctattt ggtgaaggtg
   109201 taaaaactcg cttgaaacaa aaactggtag atgagttcaa cttgcatacg attattaggt
   109261 tgcctcatag tgtctttgca ccgtatacag gaatccatac gaacattctt ttctttgata
   109321 aaacaaagaa aacagaagaa acttggtttt atcgtttaga tatgccagat ggttataaaa
   109381 atttctcgaa aactaagccg atgaagtcag aacacttcaa tcctgttcgt gactggtggg
   109441 aaaatcgtga agagattctg gaaggtaagt tctacaaatc taaatcattt acacctagtg
   109501 aattggctga gttgaattat aatttagacc agtgtggctt tccaaaagag gaagaggaaa
   109561 tcttaaatcc ctttgagttg attcagaatt atcaagcgga aagagcaact ttaaatcata
   109621 agattgataa tgtattagct gatattttgc agttgttgga ggacaaataa tgacaccaga
   109681 acaacttaaa gcaagtattc tccaaagagc gatggaaggg aaattagtgc cgcaaaatcc
   109741 caatgacgaa cctgcaagtg aattattaaa gagaattaaa gctgaaaaag aaaaacttat
   109801 cagtgaagga aaaatcaaac gagataaaaa ggaaactgag atatttcgtg gtgatgatgg
   109861 gaaacattat gggaagtttg ctgatggaag cactcaagaa attgatgttc cttatgatat
   109921 tcctgatact tgggagtggg tgaggttttc tacattggtt gaaattgtca gaggtggctc
   109981 tccacgacca atcaaagatt atcttacttc tgaagtagat ggaataaatt ggataaaaat
   110041 aggtgatact gaaaagggtg aaaagtatat aaataatgtt aaagaaaaaa tcaaaaaatc
   110101 agggcttaac aaaactagat ttgtaaaaaa aggtacattt ttgttaacta attctatgag
   110161 ttttggtaga ccttatattt tgaatgttga tggtgcaata cacgatggat ggttggctat
   110221 ttcgaactat gaaaactcat taaataaaga ttatctattc tatattcttt catcaaatgt
   110281 agtttattct caatttctat ctctaattag tggagctgtt gtgaaaaact tgaatagtga
   110341 taaagttgct tctattctta tc
//
LOCUS       DAVDFK010000002        96670 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.02, whole genome shotgun sequence.
ACCESSION   DAVDFK010000002 DAVDFK010000000
VERSION     DAVDFK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 96670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.02"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..314)
                     /locus_tag="VUR04_000109"
     CDS             complement(<1..314)
                     /locus_tag="VUR04_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5340087.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKIAVAETSLVKKNHQI
                     PR"
     gene            complement(565..1500)
                     /locus_tag="VUR04_000110"
     CDS             complement(565..1500)
                     /locus_tag="VUR04_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET5340088.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1497..2357)
                     /locus_tag="VUR04_000111"
     CDS             complement(1497..2357)
                     /locus_tag="VUR04_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5340089.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELSQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYIRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2465..4627
                     /locus_tag="VUR04_000112"
     CDS             2465..4627
                     /locus_tag="VUR04_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET5340090.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSC
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQIEKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYENQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEIYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4719..5978
                     /locus_tag="VUR04_000113"
     CDS             4719..5978
                     /locus_tag="VUR04_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5340091.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5992..6858
                     /locus_tag="VUR04_000114"
     CDS             5992..6858
                     /locus_tag="VUR04_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5340092.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6872..7705
                     /locus_tag="VUR04_000115"
     CDS             6872..7705
                     /locus_tag="VUR04_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5340093.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLNEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8016..9458
                     /gene="gtfA"
                     /locus_tag="VUR04_000116"
     CDS             8016..9458
                     /gene="gtfA"
                     /locus_tag="VUR04_000116"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET5340094.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9596..10789
                     /locus_tag="VUR04_000117"
     CDS             9596..10789
                     /locus_tag="VUR04_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET5340095.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11476..13455
                     /locus_tag="VUR04_000118"
     CDS             11476..13455
                     /locus_tag="VUR04_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340096.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13522..15018
                     /locus_tag="VUR04_000119"
     CDS             13522..15018
                     /locus_tag="VUR04_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340097.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15018..15944
                     /locus_tag="VUR04_000120"
     CDS             15018..15944
                     /locus_tag="VUR04_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340098.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15953..17020
                     /locus_tag="VUR04_000121"
     CDS             15953..17020
                     /locus_tag="VUR04_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340099.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17031..17957
                     /locus_tag="VUR04_000122"
     CDS             17031..17957
                     /locus_tag="VUR04_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340100.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(18032..19358)
                     /locus_tag="VUR04_000123"
                     /pseudo
     CDS             complement(18032..19358)
                     /locus_tag="VUR04_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(19513..20223)
                     /gene="treR"
                     /locus_tag="VUR04_000124"
     CDS             complement(19513..20223)
                     /gene="treR"
                     /locus_tag="VUR04_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET5340101.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            20408..22375
                     /gene="treP"
                     /locus_tag="VUR04_000125"
     CDS             20408..22375
                     /gene="treP"
                     /locus_tag="VUR04_000125"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET5340102.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVIAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPTADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            22553..24178
                     /gene="treC"
                     /locus_tag="VUR04_000126"
     CDS             22553..24178
                     /gene="treC"
                     /locus_tag="VUR04_000126"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET5340103.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            24434..24682
                     /locus_tag="VUR04_000127"
     CDS             24434..24682
                     /locus_tag="VUR04_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET5340104.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            24889..25683
                     /gene="racE"
                     /locus_tag="VUR04_000128"
     CDS             24889..25683
                     /gene="racE"
                     /locus_tag="VUR04_000128"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET5340105.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            25680..26651
                     /locus_tag="VUR04_000129"
     CDS             25680..26651
                     /locus_tag="VUR04_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET5340106.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            26627..27148
                     /locus_tag="VUR04_000130"
     CDS             26627..27148
                     /locus_tag="VUR04_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET5340107.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            27145..27606
                     /locus_tag="VUR04_000131"
     CDS             27145..27606
                     /locus_tag="VUR04_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5340108.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            27597..28337
                     /gene="xerD"
                     /locus_tag="VUR04_000132"
     CDS             27597..28337
                     /gene="xerD"
                     /locus_tag="VUR04_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET5340109.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            28337..29065
                     /locus_tag="VUR04_000133"
     CDS             28337..29065
                     /locus_tag="VUR04_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET5340110.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            29084..29653
                     /locus_tag="VUR04_000134"
     CDS             29084..29653
                     /locus_tag="VUR04_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET5340111.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            29640..30362
                     /locus_tag="VUR04_000135"
     CDS             29640..30362
                     /locus_tag="VUR04_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5340112.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLHP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            30362..30604
                     /gene="yidD"
                     /locus_tag="VUR04_000136"
     CDS             30362..30604
                     /gene="yidD"
                     /locus_tag="VUR04_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET5340113.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(30829..31794)
                     /locus_tag="VUR04_000137"
     CDS             complement(30829..31794)
                     /locus_tag="VUR04_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340114.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGVADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(31890..32642)
                     /locus_tag="VUR04_000138"
     CDS             complement(31890..32642)
                     /locus_tag="VUR04_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5340115.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(32639..33595)
                     /locus_tag="VUR04_000139"
     CDS             complement(32639..33595)
                     /locus_tag="VUR04_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET5340116.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(33585..34544)
                     /locus_tag="VUR04_000140"
     CDS             complement(33585..34544)
                     /locus_tag="VUR04_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340117.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(34967..35668)
                     /gene="galE"
                     /locus_tag="VUR04_000141"
     CDS             complement(34967..35668)
                     /gene="galE"
                     /locus_tag="VUR04_000141"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET5340118.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLKENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            36068..37132
                     /gene="pepA"
                     /locus_tag="VUR04_000142"
     CDS             36068..37132
                     /gene="pepA"
                     /locus_tag="VUR04_000142"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET5340119.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            37154..37450
                     /locus_tag="VUR04_000143"
     CDS             37154..37450
                     /locus_tag="VUR04_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET5340120.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            38132..38575
                     /locus_tag="VUR04_000144"
     CDS             38132..38575
                     /locus_tag="VUR04_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5340121.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            38579..39343
                     /locus_tag="VUR04_000145"
     CDS             38579..39343
                     /locus_tag="VUR04_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET5340122.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRIIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            39358..40086
                     /locus_tag="VUR04_000146"
     CDS             39358..40086
                     /locus_tag="VUR04_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340123.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            40079..41599
                     /locus_tag="VUR04_000147"
     CDS             40079..41599
                     /locus_tag="VUR04_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET5340124.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLGLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELETVLNKLAGKITESQMSQLNYQVGVEGKPAEQVAKEFLQEQGLLKK"
     gene            41944..42750
                     /locus_tag="VUR04_000148"
     CDS             41944..42750
                     /locus_tag="VUR04_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET5340125.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(42916..43452)
                     /locus_tag="VUR04_000149"
     CDS             complement(42916..43452)
                     /locus_tag="VUR04_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET5340126.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            43585..44475
                     /locus_tag="VUR04_000150"
     CDS             43585..44475
                     /locus_tag="VUR04_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET5340127.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILNLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            44719..45072
                     /locus_tag="VUR04_000151"
     CDS             44719..45072
                     /locus_tag="VUR04_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET5340128.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            45073..46110
                     /locus_tag="VUR04_000152"
     CDS             45073..46110
                     /locus_tag="VUR04_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET5340129.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAAFECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(46157..47164)
                     /gene="galR"
                     /locus_tag="VUR04_000153"
     CDS             complement(46157..47164)
                     /gene="galR"
                     /locus_tag="VUR04_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET5340130.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            47328..48506
                     /locus_tag="VUR04_000154"
     CDS             47328..48506
                     /locus_tag="VUR04_000154"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET5340131.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKREDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            48525..50006
                     /locus_tag="VUR04_000155"
     CDS             48525..50006
                     /locus_tag="VUR04_000155"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET5340132.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            50076..50480
                     /locus_tag="VUR04_000156"
     CDS             50076..50480
                     /locus_tag="VUR04_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET5340133.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGKNVCKATFTMFVTGQRSEDRQVRI"
     gene            50661..51425
                     /locus_tag="VUR04_000157"
     CDS             50661..51425
                     /locus_tag="VUR04_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HET5340134.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            51422..51883
                     /locus_tag="VUR04_000158"
     CDS             51422..51883
                     /locus_tag="VUR04_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HET5340135.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(51934..53196)
                     /locus_tag="VUR04_000159"
     CDS             complement(51934..53196)
                     /locus_tag="VUR04_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET5340136.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(53196..53777)
                     /locus_tag="VUR04_000160"
     CDS             complement(53196..53777)
                     /locus_tag="VUR04_000160"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET5340137.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(54177..54272)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(54655..54783)
                     /locus_tag="VUR04_000161"
     CDS             complement(54655..54783)
                     /locus_tag="VUR04_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HET5340138.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHEFAVLDPNGYFLRFSE"
     gene            complement(54894..55037)
                     /locus_tag="VUR04_000162"
     CDS             complement(54894..55037)
                     /locus_tag="VUR04_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET5340139.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(55049..55876)
                     /gene="xth"
                     /locus_tag="VUR04_000163"
     CDS             complement(55049..55876)
                     /gene="xth"
                     /locus_tag="VUR04_000163"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET5340140.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            56010..56466
                     /locus_tag="VUR04_000164"
                     /pseudo
     CDS             56010..56466
                     /locus_tag="VUR04_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            56619..56915
                     /locus_tag="VUR04_000165"
     CDS             56619..56915
                     /locus_tag="VUR04_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET5340141.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            57121..58866
                     /locus_tag="VUR04_000166"
     CDS             57121..58866
                     /locus_tag="VUR04_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5340142.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPELPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLSLSAVVEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            58856..60607
                     /locus_tag="VUR04_000167"
     CDS             58856..60607
                     /locus_tag="VUR04_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340143.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLRENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYYGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            60780..61472
                     /locus_tag="VUR04_000168"
     CDS             60780..61472
                     /locus_tag="VUR04_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET5340144.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            61515..62741
                     /locus_tag="VUR04_000169"
     CDS             61515..62741
                     /locus_tag="VUR04_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET5340145.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            63872..66031
                     /gene="pfbA"
                     /locus_tag="VUR04_000170"
     CDS             63872..66031
                     /gene="pfbA"
                     /locus_tag="VUR04_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET5340146.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPIEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            66015..66311
                     /locus_tag="VUR04_000171"
     CDS             66015..66311
                     /locus_tag="VUR04_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340147.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
     gene            66642..66854
                     /locus_tag="VUR04_000172"
     CDS             66642..66854
                     /locus_tag="VUR04_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340148.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
     gene            66912..67553
                     /locus_tag="VUR04_000173"
     CDS             66912..67553
                     /locus_tag="VUR04_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HET5340149.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERVELI
                     KEDLIINESVLNIDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISKIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            67566..69041
                     /gene="galT"
                     /locus_tag="VUR04_000174"
     CDS             67566..69041
                     /gene="galT"
                     /locus_tag="VUR04_000174"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET5340150.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPNQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            69054..70064
                     /gene="galE"
                     /locus_tag="VUR04_000175"
     CDS             69054..70064
                     /gene="galE"
                     /locus_tag="VUR04_000175"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET5340151.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            70244..70903
                     /locus_tag="VUR04_000176"
     CDS             70244..70903
                     /locus_tag="VUR04_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET5340152.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            70928..71995
                     /locus_tag="VUR04_000177"
     CDS             70928..71995
                     /locus_tag="VUR04_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5340153.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            72098..73108
                     /locus_tag="VUR04_000178"
     CDS             72098..73108
                     /locus_tag="VUR04_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340154.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETKQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            73120..74811
                     /locus_tag="VUR04_000179"
     CDS             73120..74811
                     /locus_tag="VUR04_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5340155.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSHDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            74814..75524
                     /locus_tag="VUR04_000180"
     CDS             74814..75524
                     /locus_tag="VUR04_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET5340156.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            75620..75987
                     /locus_tag="VUR04_000181"
                     /pseudo
     CDS             75620..75987
                     /locus_tag="VUR04_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            76095..77096
                     /locus_tag="VUR04_000182"
     CDS             76095..77096
                     /locus_tag="VUR04_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5340157.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            78328..79689
                     /gene="trpE"
                     /locus_tag="VUR04_000183"
     CDS             78328..79689
                     /gene="trpE"
                     /locus_tag="VUR04_000183"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET5340158.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            79686..80252
                     /locus_tag="VUR04_000184"
     CDS             79686..80252
                     /locus_tag="VUR04_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET5340159.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            80263..81267
                     /gene="trpD"
                     /locus_tag="VUR04_000185"
     CDS             80263..81267
                     /gene="trpD"
                     /locus_tag="VUR04_000185"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET5340160.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            81264..82031
                     /gene="trpC"
                     /locus_tag="VUR04_000186"
     CDS             81264..82031
                     /gene="trpC"
                     /locus_tag="VUR04_000186"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET5340161.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVNIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            82018..82617
                     /locus_tag="VUR04_000187"
     CDS             82018..82617
                     /locus_tag="VUR04_000187"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET5340162.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQANYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            82595..83818
                     /gene="trpB"
                     /locus_tag="VUR04_000188"
     CDS             82595..83818
                     /gene="trpB"
                     /locus_tag="VUR04_000188"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET5340163.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            83811..84587
                     /locus_tag="VUR04_000189"
     CDS             83811..84587
                     /locus_tag="VUR04_000189"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET5340164.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(84559..85218)
                     /locus_tag="VUR04_000190"
     CDS             complement(84559..85218)
                     /locus_tag="VUR04_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET5340165.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            85288..85734
                     /locus_tag="VUR04_000191"
     CDS             85288..85734
                     /locus_tag="VUR04_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340166.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            complement(85962..87140)
                     /locus_tag="VUR04_000192"
     CDS             complement(85962..87140)
                     /locus_tag="VUR04_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET5340167.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            87420..88682
                     /locus_tag="VUR04_000193"
     CDS             87420..88682
                     /locus_tag="VUR04_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5340168.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            88685..89581
                     /locus_tag="VUR04_000194"
     CDS             88685..89581
                     /locus_tag="VUR04_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET5340169.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            89596..89913
                     /locus_tag="VUR04_000195"
     CDS             89596..89913
                     /locus_tag="VUR04_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5340170.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            89930..90247
                     /locus_tag="VUR04_000196"
     CDS             89930..90247
                     /locus_tag="VUR04_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5340171.1"
                     /translation="MDESNLESVMGLIMYGGDAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            90257..91612
                     /locus_tag="VUR04_000197"
     CDS             90257..91612
                     /locus_tag="VUR04_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5340172.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGCFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            91936..93411
                     /locus_tag="VUR04_000198"
     CDS             91936..93411
                     /locus_tag="VUR04_000198"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET5340173.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            93408..94256
                     /locus_tag="VUR04_000199"
     CDS             93408..94256
                     /locus_tag="VUR04_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET5340174.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGLQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            94271..95041
                     /locus_tag="VUR04_000200"
     CDS             94271..95041
                     /locus_tag="VUR04_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET5340175.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(95319..95606)
                     /locus_tag="VUR04_000201"
     CDS             complement(95319..95606)
                     /locus_tag="VUR04_000201"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5340176.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            95804..96082
                     /locus_tag="VUR04_000202"
                     /pseudo
     CDS             95804..96082
                     /locus_tag="VUR04_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            96208..>96670
                     /locus_tag="VUR04_000203"
     CDS             96208..>96670
                     /locus_tag="VUR04_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5340177.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFEHDFSRLPKIM"
BASE COUNT        29093 a        16907 c        21171 g        29499 t
ORIGIN      
        1 atacgaggga tttggtgatt tttcttgacg agggaagtct cagcgaccgc tatttttgag
       61 cactgatagc acttaaagcg acgctttcta aggaggattc tagtaggcat accagttgtc
      121 tcaaggtaag gaattttaga aggtttttga aagtcatatt tcttcaattg gtttccgcac
      181 tcagggcaag atggagcctc ataatccagc ttagcgataa tttctttgtg ggtatccata
      241 ttgatgatat ctagaatctt gatgtttggg tctttaatgt ctagtaattt tgtgataaaa
      301 tgtaattgtt ccatatgatt ctttctaatg agttgttttg tcgcttttca ttatagatct
      361 tatgggactt ttttctgcac aaaaataggc tccataatat ccatagggga tttacccact
      421 acaaatatta tagagcccgt tttaatgaga gtttgtaact ctctttttta tttttagaga
      481 caataaaact tcagatccgt aaaacttaat tgaattacta atctgaagtt atttttatat
      541 cgtttatatt ataattgtgt tattttactt ccaactattg agagaaattt cgccactatt
      601 tagccagatt tcttttccgt tatcacattg aattaaaagt tttccatttt ctgagatgtc
      661 tttagcaagt cccttgtagt ctttttgctc tagtgtgaaa gtgacttctt ttcctagaat
      721 gaatgactgt tttttgtata ggtataatag ctcttctgct ggtgtttcga agaaagcacg
      781 ccagatttct atgatcaatt cattccttgt tataggagct gtagctttaa ataagctggc
      841 agctttttct tttaattcct gagggaagtc tttaatagtg aaattgatac ctactccaat
      901 aatgatatct gtgactaagc cagtttctac agaggtcatt gcttcagtaa ggattcctcc
      961 aattttatga ttgtttagat agatatcatt gacccatttt atgtcgacat ctattaaagt
     1021 taggttctta atagctttgt agacagctcc agctacaagt agtgtgtagg atggtaattt
     1081 gtcatagggg agatttggtt taagatggag tgtcatataa ataccacctt gtggtgagta
     1141 gaaggaacgt tgaaaacggc ctcggcctgc tgtttgatag gaagctagat agagggtatt
     1201 tgcttcatgg cctaaatcaa ttgcttcttt tgcatctagt tgtgttgatt ttgtttcggg
     1261 tttaaaactg actttaattg gaagattttc ttctagaatc tctggaagaa taaggtcacc
     1321 attcatcagt ttatatcctc tatttttgat actatcaatt tcaatgcctt cttgttctag
     1381 tcgcttgata gctttccaaa ttgatgttcg gcttagggat agtttttctg cgattttttc
     1441 tccgctgata tagtcggttt ctttagatag gatttggtag acagcttggt aggatttcat
     1501 aatgttgcct ttctcactag ttggtattga gagtattctt ttcttgtatg acttggagtc
     1561 tgattaaagt attgtttata agctttcgaa aaatggagtg gatctgaaaa acctaccgag
     1621 tatgcaatta ccttgatgga ctcttgggta ttttcgagaa gttgtctagc tcggtgcatt
     1681 cgaatgtaga gtaggtattc tttgggtgat aaggtattaa attctttgaa tacgcttgat
     1741 aagtagcttc tgtgaacgga tagttctttt gctaaatctt gaattgtaag tgattgagga
     1801 tagtggctat caattaatcg tttgcattca agatagagtt ggtgggttga tgaaatattc
     1861 ttttttttct gattgggagc aatagttccc agatgaaaca tcagttcatg aagttgtccc
     1921 atgatatgga gttgagataa ttcacttgat tttgtaatct gagcgaagcg gacaatgtct
     1981 gagatgagtt ttgcagtagt ctgggtatga caagtttcag attggatgag ataggattga
     2041 tcagaaattt gagaaagagc aaaataatca ggggatttcc ctccagtgat tcctaaccag
     2101 tagtaggccc aaggttcttt actatctgct tgataaaagg ttagttcctc tggttttaat
     2161 agaaagaaat ctccttcttt taaatcaaca attttaccct tgtaatgaaa ttttccttgt
     2221 cctttagtaa tgtaatgtag gacgtatgta tcacgaatgg ctggaccaaa agagtaatta
     2281 ggtgtgcatt cctcatatcc ataaaagctt agggcaaggt caattgttcc agtctggtat
     2341 tctgaaaaaa ctagcatgtg ctacctccta cctaacattt taccatattc ttgagacatt
     2401 tttctatttt ggaaagcgat ttcaggtgat aaaatataat caataaagtg atgaggtgaa
     2461 gtaaatggga gttaggatag agaataatct attttatgtt gagagtaaaa atctaagttt
     2521 gattattgaa aatcgaaatg gctacttact tttgaaacat ttaggaaaga ctattaagaa
     2581 ctataaaggt tccaatagtg tttatgaacg agaccatgcc ttttcaggaa atccaacggc
     2641 tactaatcga acctttagtt tagatactca gcgacagatt tttggacaac atggcttagg
     2701 agattttagg aaaccaacca tacaggttca gcatagtgta actgaagtaa cagactttcg
     2761 atttgtagaa gcaaagattt taaaaggtca gaatggtcca cagggcttac cttctccaca
     2821 tagcatggac gatacagaga ctcttgtctt aatgttagaa gattctaagg ctcaacttag
     2881 tctgactttg tattatacta cttttaataa tgatgcgact attgctagct acagtaaatt
     2941 agataataat agtaatcagg aagttgtcat ccataaagat ttttctttta tggctgattt
     3001 tccagctgca gattacgaaa tagtaactct gcagggtgct tatgctcgtg aaaagactgt
     3061 tagacgtcaa caggtagaac aaggaatctt ttcgattagc tcaaaccgag gtgcttctgg
     3121 tcatgctcaa acaccagctc ttttactatg cgaacaagga gtcacagagg atgctgggaa
     3181 tgtgtttgct attcaactaa tgtatagtgg caactttgaa gcttttgttc aaaaaaatca
     3241 attgaatgaa gttcgggtgg ctattggcat taatccagaa aacttttctt gtaagttagc
     3301 tcctgaggaa tactttgaaa caccggtagc tttagtgacc cattcagatc agggattaac
     3361 tggtattagt catgaaagtc agaattttgt actgaagcac attatgctaa gtgaattttc
     3421 taaaaaagaa cgtccaattc taatcaataa ctgggaagct acttactttg actttcagat
     3481 agaaaaactg ttagagttag cagatgaagc taagaaagtt ggcattgaac tttttgtatt
     3541 agatgatggt tggtttggca atcgttttga tgataatcgt gctttaggtg attgggttgt
     3601 taatgaggaa aaactgggtg gaagtctaga aagtctgatt tcagctatcc atgaaagagg
     3661 tttgcagttt ggactttggt tagaacccga aatgatttct gtagatagtg atttgtatcg
     3721 tcgacatcct gactgggcta ttcaggttcc tgactatgag catacttatt ctcggaatca
     3781 attagtactt aatcttgcca atcctcaggt agtagaatac ttgaaaagtg tcttagatca
     3841 actcctatct tatcatgata ttgattacat taaatgggat atgaaccgca atatcactaa
     3901 gctagggaat ggattaactt atctagagac acagatgcaa tctcatcagt acatgctggg
     3961 gctttacgaa ctcgtttctt atctgacaga gaagcacagc catattctct ttgagtcctg
     4021 ctctggtggt ggtggacgaa atgatcttgg tatgatgcgc tatttcccac aagtttgggc
     4081 tagtgataat actgatgcca ttgcacgttt accaattcaa tacggttcat cctatctcta
     4141 tccaaccatt tctatggggg ctcatgtgtc agcagtaccg aatcatcaga tgggacgaat
     4201 gacaccatta gaaacacgtg gccttgtagc aatgatggga aatttgggct atgaacttga
     4261 tttgacaaat ttatcagatg aagagaaagc tacgattgct aatcaggtga acttgtataa
     4321 agaattacga ccagtagttc agttaggaca gcagtataga ctaattaatc ctgatactgt
     4381 atccaatgaa gcagctgtac aatttaatta cgaaaatcaa acgattgtaa cctacgttcg
     4441 cgttttatct gttgtagaga ccatggaaac aactttaaaa ttaaaagatt tggatgaaga
     4501 gggactatat aaattacagg aaaatggcga aatttactca ggtgcagaac taatgtatgc
     4561 gggcttaact gttatcttat cccaaggaga ttttttgagt agacagtata tttttagaaa
     4621 actatgatat gtactgaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     4681 tcaataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat aaaaaaatcg
     4741 gacttcttgc aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta
     4801 aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa
     4861 ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg
     4921 tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg
     4981 atgtggtcaa tatttaccca cagtccatcg aactgcaaga atgggcaaaa gcaggtgtct
     5041 ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat
     5101 atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact
     5161 acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg
     5221 aacagttagt caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag
     5281 atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa
     5341 aagaagcaaa tcaatacctt cgttattctc aaccaaatgc tattaaattg tcggatccga
     5401 ttatgaaaga tgatatcaag gtcatggaca tccttcgcat taatggctct aagcaaaaga
     5461 actgggaagg tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca
     5521 tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga
     5581 ttgggacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag
     5641 acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg
     5701 aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag
     5761 cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg
     5821 cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc
     5881 ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc aatgatttga
     5941 atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa
     6001 gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt
     6061 ttcttctatg taccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg
     6121 acttataact acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa
     6181 ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt
     6241 gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc
     6301 cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag
     6361 caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa
     6421 accagtcttt tagggactaa gtggggagca atctttgcgg ctgcctttgt ccttctttgg
     6481 caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag
     6541 attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa
     6601 ttgccttact tgctaccaag tgtctctatg gtctttatcc tagccctaaa aggtgggctg
     6661 actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca
     6721 cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc
     6781 attgccgtaa tcttgttcct cttaattgta gtgatttcga tcatccaatt gagagtatct
     6841 aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat
     6901 tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac
     6961 cctctttagt tcctttaaac ccactaagga tattgtagat aatttctttg gctttccaac
     7021 caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag gctattattg
     7081 gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc
     7141 agcctactcc atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct
     7201 cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat
     7261 gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat
     7321 tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgaa
     7381 tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc
     7441 aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gcactttggt tctggaatga
     7501 cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt
     7561 ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt
     7621 ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg
     7681 aatgagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct
     7741 agccgcaggc tgtacttgag tacggtaagg cgacgctgac gtggtttgaa gagattttcg
     7801 aagagtataa gaagagctca tggaatctat agtctttgac acagaggaag agttcagctt
     7861 gttgataatt ctatgtagaa aacaagaaag tagtactttg tttatcacag tctatattag
     7921 tacgagtttg atgataaata gagatttaaa atgaatttga tttacgaagc cagatcatat
     7981 gagacttggc ttcaattaga aaaaggagag taatgatgcc aattcaaaat aaaaccatgt
     8041 tgattaccta ttctgatagc cttggaaata atcttaaaga cttatatgat aatttggaag
     8101 agcattttgg agatgctatt ggaggagttc accttttacc atttttccca tcaacaggtg
     8161 atcgtggatt tgcgccagtt gactacgacg aagtggactc agcttttggt gattgggagg
     8221 atgttaagcg tttaggtgag aaatattatc ttatgtttga ttttatgatt aatcatattt
     8281 ctcgtcaatc caagtattat aaggactatc aagaaaaaca tgaagccagt gaatttaaag
     8341 atctcttttt aaactgggat aagttttggc cagaaaaccg tccgacacag tctgatgtag
     8401 atttaattta caagcgtaag gatcgtgcac caaagcaaga gattgtgttt gaagatggtt
     8461 cagtggaaca tttgtggaat acctttggtg aggagcagat tgatcttgat gtgaccaaag
     8521 aagtaactat ggaatttatc cgtaagacca ttcagcactt ggcaagtaat gggtgtgatt
     8581 tgattcgtct agatgccttt gcttatgcag tgaagaaatt ggatactaat gatttctttg
     8641 tggaaccaga tatttgggat ttattggaca aagttcgaga tatcgctgct gagtatggga
     8701 cagagctttt acctgagatt catgaacact attcgattca gtttaaaata gcagaccatg
     8761 attactatgt ttatgatttt gctcttccaa tggtgacact ttatactctt tacagttcca
     8821 gaacagagcg tttggctaag tggttaaaga tgagcccgat gaagcaattt acgacgctag
     8881 atacccatga tgggattgga gtagtagatg tcaaggatat cctgaccgat gaggagattg
     8941 actatgcttc aaatgaactc tataaggttg gagctaatgt caaacgtaag tactctagtg
     9001 ccgagtataa caacttagat atctaccaaa tcaattcaac ctactattca gcgcttggag
     9061 atgatgatgt caagtatttt ctcgctcgtc taattcaagc ttttgcccca ggtattcctc
     9121 aggtttacta tgtgggtcta ttagcaggca agaatgactt gaaattatta gaagaaacta
     9181 aagaaggtcg aaatattaat cgtcattact atagcaacga ggaaatagca aaagaagtgc
     9241 aacgacctgt tgtgaaggcc cttctcaatc tattttcttt ccgtaaccgt tcagaagcct
     9301 ttgatctaga agggactact gagatagaga caccaacagc tcacagcatt gtaatcaaac
     9361 gtcaaaataa agataagtcc gtaacagcag tagcagaaat tgatttgcaa aatcagactt
     9421 atcgggtaat tgagaatgga gttgaagtaa cattttgaag ccttgatatg gtggataaaa
     9481 tagggttttt attttggaaa acgtttcctt tgttttcaaa ttgctaaaaa agtggtacaa
     9541 tataggatag cttactatta tctgaatcag ctgatttgga gagaaaggat tcattttgaa
     9601 atcaataggc tttattgaaa agctgaaggg gttgtctagt aaagagctga ttttattggg
     9661 aattatccta agtatctttt taccctttta tctttttgta gttgtactct gtttatatat
     9721 tatcagtttg atttttacag gagacatgaa aagtattctt cagaaaatgg gggagcatcc
     9781 gatgctgctt ctttttctta gctatagtac tgttatatcc attcttgcac aaaattggat
     9841 gggtcttgtg gcttcagtag gaatgtttct atttactatt ttctttttgc actatcagtc
     9901 gattttatcc cataaattct ttcgattgat tttgcagttc gtcttgtttg gtagtgtctt
     9961 gtcagctgct tttgccagtt tagaacattt ccaaattgtg aagaaattta actatgcttt
    10021 tctttcaccc aatatgcagg tgtggcatca gaaccgggca gaagtgacct tctttaatcc
    10081 taattattat ggaattattt gttgtttctg tattatgatt gctttctatc tgtttacaac
    10141 gaccaagttg aattggttga aagtattctg tgtgattgca ggctttgtta atctctttgg
    10201 tttgaacttt actcaaaatc gaactgcctt tcctgctatt atcgctggag caattatcta
    10261 tctctttacg actattaaaa actggaaggc cttttggctt agtattgggg tcttcgcgat
    10321 tggtttgagt ttcctctttt ctagtgattt gggagttcga atgggtactt tagactcttc
    10381 tatggaagaa cgcatttcta tctgggatgc tgggatggcc ttgtttaagc aaaatccttt
    10441 ttggggtgaa gggccattga cctatatgca ctcttatcct cggatacatg ctccttatca
    10501 tgaacatgcc cacagtcttt atattgatac gattctgagt tacggaattg tgggtaccat
    10561 tttattagtt ttgtcttctg ttgctcctgt tcgcttgatg atggatatga gtcaggagtc
    10621 ggggaaacgt ccgattatcg gcctttatct atctttcctt acagtggttg ctgtgcacgg
    10681 aatttttgac ttggctctct tctggattca gtcaggcttt attttcttgc tagttatgtg
    10741 cagtattcca ttggagcatc gaatgttggt atcggacatg acggattaag ttttataagt
    10801 ttgaaatctt ctaccttggg taggagattt ttttatacga tgggcatgtc gtgcatctga
    10861 ggtgtaagtc ctctgtaggg atccactacc ggtgaataca atagcgctcc ccaagcctga
    10921 ctatcgtgag gtagcggatt aaaatggtct ggggatagat cgttttaagt ctgacgcagg
    10981 aaataagaat tgtcagagaa agcaatagtg aaatcgtagg ctatgaatag aaacgtgata
    11041 gcgaggagca tatagtggat aaggtagcga gaaattttaa agtataaaag atagtcttaa
    11101 tctatatatg taaatcacaa aagtaattga attcggaata aggttggtgt gaaaagacat
    11161 agtaaactga atcttgaata ctagaatgat acttctacaa tattgttata atttaatttg
    11221 aattccaaaa tcacattgtt ccgtccgtat ttcattttac tgtatgtctt cctaaactcc
    11281 aaagtttctg cgtcaaattt cctattttca ctgtagtctt tgacacttcg aacgacaatt
    11341 tgaatcatat attcaaaaaa aaatgaaaaa tttgtgccaa caagcctaaa tattctgaaa
    11401 atttgtttga tttttaatgg ataatgtgat ataatggttg tcaatctata attcacataa
    11461 acagaggagt agaaaatgaa aaaaaatcgt gtatttgcta cagcaggtct tgttttatta
    11521 gcagcaggtg tacttgcagc atgcagttct tcaaaatcat ctgattcatc agcccctaaa
    11581 gcttatggct atgtttatac agcagaccca gaaaccttgg actacctgat ttcaagtaaa
    11641 aatagtacaa cagtagtgac ttcaaatggg attgatggtt tattcactaa cgataattac
    11701 ggtaatcttg ctcctgcagt tgcagaggat tgggaagtct ctaaggatgg tttgacctac
    11761 acttataaga ttcgtaaagg ggttaaatgg tttacctctg atggagaaga atatgcagag
    11821 gtgacggcta aagatttcgt gaacggttta aaacacgcag cagataaaaa atcagaagct
    11881 atgtatttag ctgaaaattc ggttaaaggc ttggcagatt atctatcagg aacttcaaca
    11941 gatttttcaa cagttggtgt caaggcggtt gatgattata cgttacaata cactttgaac
    12001 cagcctgaac cgttctggaa ctctaagttg acctattcta ttttctggcc tctgaatgaa
    12061 gaattcgaaa catcaaaagg aagcgatttt gctaaaccaa cagatccgac atccttgctt
    12121 tataatggtc cattcttgtt gaaagggttg actgcaaaat cttctgtaga gtttgtaaaa
    12181 aatgagcaat attgggataa agaaaatgtc cacctagata ctatcaatct agcttactat
    12241 gatggatcag atcaggagtc gctagagcgt aacttcacta gtggagctta tagttatgcc
    12301 cgtctttacc ctaccagctc caactattct aaggttgcag aagaatacaa ggacaatatc
    12361 tattacacac aatcaggctc tgggattgct ggtctgggtg tgaatattga tcgccaaagt
    12421 tacaactata cttctaaaac tacagattca gagaaagtag ctactaagaa ggcattgctt
    12481 aacaaagatt tccgtcaagc cttgaatttt gctcttgatc gctcagctta ctcagctcaa
    12541 atcaatggta aagatggagc agctttagca gttcgtaatt tatttgtaaa accagacttt
    12601 gtttcagctg gtgagaagac ctttggtgat ttagtcgctg ctcaacttcc tgcttatggt
    12661 gatgagtgga aaggtgtgaa tttagctgat gggcaggatg gtttattcaa tgctgacaag
    12721 gccaaggcag agtttgcgaa agctaagaaa gctttagaag cagacggcgt tcagtttcct
    12781 attcatctgg acgttccagt agaccaagca tcaaaaaact acatatctcg tattcagtct
    12841 tttaaacaat ctgtagaaac agttcttggt gttgaaaatg tcgttgttga tattcaacaa
    12901 atgacaagtg atgaattcct taatattact tactatgctg ccaatgcttc atctgaggat
    12961 tgggatgtat caggaggagt ttcatggggt ccagactatc aagacccatc tacttacctg
    13021 gatattttaa aaacaactag cagtgaaact acaaaaacat atttaggatt tgataatcca
    13081 aatagccctt cagtagttca agttggtttg aaagaatacg ataaattagt tgatgaagct
    13141 gccagagaga caagcgactt gaatgtccgt tatgaaaaat atgcagcggc tcaagcatgg
    13201 ttgacagata gttcactctt tattcctgct atggcttctt ctggtgcagc accagtgctt
    13261 tcacgaattg ttccatttac tggagcttct gcgcaaacag gctctaaggg gtcagatgtt
    13321 tacttcaaat atttgaaatt acaagataaa gtggtgacta aggaagagta tgaaaaagct
    13381 cgtgaaaaat ggttgaaaga aaaagctgaa tcaaatgaga aagctcaaaa agaattggca
    13441 agtcatgtga agtaaataat ttctaataga actttctctc catgaggaga aggttctttt
    13501 gggattttta aaggaaataa tatgaaaaaa tatattttta tgcgtgtttt gcggtcattg
    13561 gtttcgattt tcttagtaac gactttgacc tacacgatta tctatacctt ggttcctcga
    13621 aaattgattt tcaagcagga tcctaactat aataaaattg cgacaacggc tgataaacgt
    13681 gataactatg aaaatactgt gtttgagcgt atgggctaca ttgagtatta cgatactaaa
    13741 gagttgcaag aaaaggcaag tagcatggat tcttctgtaa cagtagaagc aaatgcgacc
    13801 aataaagcta tttatgaaaa gtacatcaat caattaggtc atggttggac tttgggagaa
    13861 tttactgaaa gtggtcaatt ctatgctact cgtgaaattc caatttttga acgtgttttt
    13921 cacttctatg ctaacttgat tgacattgac catacaaata aaatccaaga ccctgaaaat
    13981 ccagacttga aacgctacct tcgttttgaa aatgatccag ctatcggatg gtcattggtc
    14041 ggttcaggaa ctaaacataa atatctcttg tactttaaca gtcagttccc atttgttcat
    14101 caaaactttg tgaacttgaa tttaggtgac tcttacccaa cctatgctaa tacaccagtt
    14161 cttcaggtta ttactcaagg tcaaggacaa accaaaactg cccaagttca gttcccaaca
    14221 ggtaagaaaa cgtcttctgt aaatatttac tcaagaacct acaagtcacc tagtcaggct
    14281 gactctcgtg aagtagctag ctatgggaaa gatgatcctt atacagcgac tgaaagtaat
    14341 taccaatatc catctatgat tgtcagctct gctattactg gtttgattgg tttggttctt
    14401 gcctatgctc ttgccgtgcc acttggttca gccatggctc gtttcaagaa cacttggatt
    14461 gatagcctct caacagggac tttgaccttc ttgcttgctc ttccaacgat tgccttggtt
    14521 tacatcgttc gattgattgg atcatctatt gcccttccag attcattccc tatcttggga
    14581 gctggagatt ggcgttctta cgttttacca gcagtcatcc ttggtttgtt gggtgctcct
    14641 gttacagcca tttggattcg tcgttacatg attgacttgc aatctcaaga ctttgttcgt
    14701 ttcgctcgtg caaaaggttt gtctgaaaaa gaaatttcaa acaaacacat ctttaaaaat
    14761 gccatggttc cgctggtttc aggaattcct ggtgccatta ttggggttat cggtggtgca
    14821 acccttactg aaacagtctt cgccttccca ggtatgggta aaatgttgat tgactctgta
    14881 aaagcatcta ataactctat ggtcgttggt cttgtcttca tctttacatg tatttctatc
    14941 ttctcacgtc ttttgggaga tatttggatg actattattg acccacgtat taaattgact
    15001 gagaaaggag gcaaataatg tctacaatcg ataaagaaaa atttcagttt gtaaaacgtg
    15061 acgattttgc ctctgaaact attgatgcgc cagcatattc ttactggaaa tcagtgttta
    15121 aacaatttat gaagaaaaaa tcaactgtag tcatgttggg aatcttggta gccatcattt
    15181 tgataagttt catctaccca atgttttcta agtttgattt caatgatgtc agcaaggtaa
    15241 acgactttag tgttcgttat atcaagccaa atgcggagca ttggttcggt actgacagta
    15301 acggtaaatc gctctttgac ggtgtctggt tcggagctcg taactccatc ctcatttctg
    15361 tgattgcgac agtgattaac ttggttatcg gtgtttttgt cggtggtatt tggggtattt
    15421 caaaatcagt tgaccgtgtc atgatggaag tttacaacgt catctcaaac atcccacctc
    15481 ttttgattgt tattgtcttg acttactcaa tcggagctgg attctggaat ctgatttttg
    15541 ccatgagcgt aacaacatgg attggtattg ccttcatgat ccgtgtgcaa atcttgcgct
    15601 atcgtgactt ggaatacaac ttggcgtcac gtactttggg aacaccaacc ttgaagattg
    15661 ttgccaaaaa tatcatgcct caattggtat ctgttattgt gacaaccatg actcaaatgc
    15721 ttccaagctt tatctcatac gaagccttct tgtctttctt cggtcttgga ttaccgatta
    15781 cagtgccaag tttgggtcgt ttgatttcgg attattcaca aaacgtaaca accaatgctt
    15841 acttgttctg gattccattg acaacccttg tcttggtatc cttgtccctt ttcgtagttg
    15901 gtcaaaactt agcggatgct agtgatccac gtacacatag ataggagtag aaatgacaaa
    15961 agaaaaaaat gtaattttga ctgctcgcga tattgtcgtg gaatttgacg ttcgtgacaa
    16021 agtattgaca gccattcgcg gcgtttccct tgaactagtt gaaggagaag tattagcctt
    16081 ggtaggtgag tcaggatcag gtaaatctgt tttgacaaag accttcacag gtatgctcga
    16141 agaaaatggt cgtattgccc aaggtagtat tgactaccgt ggtcaggact tgacagcttt
    16201 atcttctcac aaggagtggg aacaaattcg tggtgctaag attgcgacta tcttccagga
    16261 cccaatgact agtttggacc ccattaaaac aattggtagt cagattacag aagttattgt
    16321 aaaacaccaa ggaaaaacag ctaaagaagc gaaagaattg gccattgact acatgaataa
    16381 ggttggcatt ccagacgcag atagacgttt taatgaatac ccattccaat attctggagg
    16441 aatgcgtcaa cgtatcgtta ttgcgattgc ccttgcctgc cgacctgatg tcttgatctg
    16501 tgatgagcca acaactgcct tggatgtaac tattcaagct cagattattg atttgctaaa
    16561 atctttacaa aacgagtatc atttcacaac aatctttatt acccacgacc ttggtgtggt
    16621 ggcaagtatt gcggataagg tagcggttat gtatgcagga gaaatcgttg agtatggaac
    16681 ggttgaggaa gttttctatg accctcgcca tccatataca tggagtctct tgtctagctt
    16741 gcctcagctt gctgatgata aaggggatct ttactcaatc ccaggaacac ctccgtcact
    16801 ttatactgac ctgaaagggg atgcttttgc cttgcgttct gactacgcaa tgcagattga
    16861 cttcgaacaa aaagctcctc aattctcagt atcagagaca cattgggcta aaacttggct
    16921 tcttcatgag gatgctccaa aagtagaaaa accagctgtg attgcaaatc tccatgataa
    16981 gatccgtgaa aaaatgggat ttgcccatct ggctgactag gaggaaggaa atgtctgaaa
    17041 aattagtaga aatcaaagat ttagaaattt ccttcggtga aggaagtaag aagtttgtcg
    17101 cggttaaaaa tgctaacttc tttatcaaca agggagaaac tttctcgctt gtaggtgagt
    17161 ccggtagtgg gaaaacaact attggtcgtg ctatcatcgg tctaaatgat acaagtaatg
    17221 gagatatcat ttttgatggt caaaagatta atggtaagaa atcgcgtgaa caagctgcgg
    17281 aattgattcg tcgaatccag atgattttcc aagaccctgc cgcaagtttg aatgaacgtg
    17341 cgactgttga ttatattatt tctgaaggtc tttacaatca ccgtttattt aaggatgaag
    17401 aagaacgtaa agagaaagtt caaaatatta tccgtgaagt aggtcttctt gctgagcact
    17461 tgactcgtta ccctcatgaa ttctcaggcg gtcaacgtca acgtatcggt attgcccgtg
    17521 ccttggtcat gcaaccagac tttgttattg cagatgagcc aatttcagcc ttggacgttt
    17581 ctgtacgtgc ccaagtcttg aacttgctca aaaaattcca aaaagagctc ggcctgacct
    17641 atctcttcat cgcccatgac ttgtcggttg ttcgctttat ttcagatcgt atcgcagtta
    17701 tttacaaggg tgttattgta gaggttgcag aaacagaaga attgtttaac aatccaattc
    17761 acccatatac tcaagccttg ctttcagcgg taccaatccc agatccaatc ttggaacgta
    17821 agaaggtctt gaaggtttac gacccaagtc aacacgacta tgagactgat aagccgtcta
    17881 tggtagaaat ccgtccaggt cactatgttt gggcgaacca aaccgaattg gcacgttatc
    17941 aaaaaggact aaactagtaa tggttttata atttccatgt caatttttat ggaaattagg
    18001 ctctttgtca actgtagtgg gttgaagtca gctaagctcg agaaaggaca aatttcgtcc
    18061 tttctttttt gatgttcaaa gcgataaaaa tccgtttttt gaagttttca aagtttcgaa
    18121 aaccaaaggc attgcgcttg ataagtttga tgagattatt ggtcgcttcc agtttggcat
    18181 tagaatagtg tagttgaagg gcgttgataa tcttttcttt atctttgagg aaggttttaa
    18241 agacagtctg aaaaatagga tgaacctgct taagattgtc ctcgataagt tcgaaaaatt
    18301 tctctggttc cttattctgg aagtgaaaaa gcaagagctg atagagctga tagtggtgtt
    18361 tcaagtcttg tgaataactc aaaagcttgt ttaaaatctc tttattggtt aaatgcatac
    18421 gaaaagtagg acgataaaat cgcttatcac tcagtttacg gctatcctgt tgtatgagct
    18481 tccagtagcg cttgatagcc ttgtattcat gggattttcg atgaaactga ttcatgattt
    18541 gaacacgcac acgactcata gcacggctaa gatgttgcac aatgtgaaag cgatcaagaa
    18601 cgattttagc attcgggagt gaaacagtct gggagactgt ttcagcctga gtctagaaat
    18661 ttgaaagcga agctgtttag ccaagtcata gtaagggcta aacatatcca tagtaatgat
    18721 tttgacgcga catcggacgg ctctatcata tttaagaaag tgatctcgga tgacagcttg
    18781 tgttctacct tcaagaatag tgatgatatc gagcttttca aaatcttgcg caataaagct
    18841 catctccatc tcccgattga aacagtcact ccccggactg tttcaacgtc ccaagacata
    18901 atcttaggca gatttctaaa attacactca aagtggaagt cattgagctt tcgaatgaca
    18961 gttgaagttg agatggaaag ctgatgggca atatcagtca tagaaatctt ttcaattaac
    19021 ttttgagcaa tcttttggtt gatgatacga gggatttgat gattcttctt gacgatagaa
    19081 gtttcagcaa ccataatttt agaacaatga tagcacttga aacgacgctt tctaaggaga
    19141 attctagtag gcataccagt tgtttcaaga taaggaattt tagaaggttt ttgaaagtaa
    19201 tatttcttca tttgacttcc gcactcagga caagatggag cttcatagtc cagtttggcg
    19261 atgatttcct tgtgtgtatc cttattgatg atgtctaaaa tctggatatt agggtcttta
    19321 atgtctagta attttgtgat aaaatgtaat tgttccatat gattctttct aatgagttgt
    19381 tttgtcgctt ttcattatag gtcatatggg actttttttc tacacaaaat aggctccata
    19441 atatccatag gggggttacc cactacaaat attatagagc cgaaaaaggc tgagatctgg
    19501 tgtctcagtc ttttatttct tgcgttttgc aaaatctaca aatctaaatt tttctaactt
    19561 atggcgactt tcggtaaact gaaattggcg tccgtcttgg agatagactt ttgatttaat
    19621 cgaaacgaca taagggtctt tgccaatgtc catgagaatc ttgtctcggt cgcttgagtg
    19681 gtcaatggtg atttccttct gagcataatc aataaggagt ttgaggccat tttctatata
    19741 agaatagata gactgctcag caatttggcg agtgagattt ggaattagtt ccatatccag
    19801 atagtctgta tccagaacgg ataccagatc atccaccaca cgctggcgga ccaccttcca
    19861 aaccatccga aactctggga aaccggttat cagtgaggat tttttatcaa taataatctt
    19921 gtccagactg accacgttgg ttttagagcg cagtccaagt tctttaacta gttcttggta
    19981 gctggttagg ttggatacag ggaaattgac ggtttcttct ttgacgactt gagaaccttg
    20041 ccctcttatc tttttgatca atccttcctc ttggaggaga gacagggcct ttcggacggt
    20101 atcacgactc acttgatatt gctccataag gtcgtgctcg ctaggaagga aatctccgac
    20161 agcgtaagtc tcgttttgaa tggtttcttg gatttgctta aataattgtt ggtatttctt
    20221 cattttgcct gcttaaatag gtttttagtc tagtttaatg aacacctgta tctattttac
    20281 catacaagtg ctagaaaatt tacaaaaaaa cacccttttt ataccaaaca agttgcagac
    20341 aagtttggta tcgtttacaa tatacttatc aaatcaaact tgctttgaca agtataagga
    20401 gaatcaaatg ggaaaatttg aacaagaagc caaagatctg cttcaggcaa ttggaggcaa
    20461 agaaaatgtg attgccgtaa ctcactgtgc gacacggatg cgctttgttt taggagatga
    20521 taagaaggct aatgttaaag ctatcgagtc aattccagct gttaaaggaa cttttacaaa
    20581 tgcaggtcaa tttcaggtaa tcattggaaa tgacgtgccc atcttttata atgattttac
    20641 agccgtttca ggtattgagg gtgtttccaa agaagcagcc aagtctgcag ctaagagtaa
    20701 tcaaaacgtg gtccaacgtg ttatgaccac tctggcggag atttttactc cgattattcc
    20761 agccttgata gtcggaggat tgatcctcgg tttccgtaat gtcttggaag gtgtccattg
    20821 gtcgatgttg gatggcaaga ccatcacaga atcctctcag ttttgggcag gtgtcaatca
    20881 cttcctctgg ttgcctggtg aagctatctt ccagttctta ccagtaggga ttacttggtc
    20941 tgtttctcgt aagatgggaa ccagccaaat tttgggaatt gttctcggaa tctgtttggt
    21001 atcgcctcag ttgctcaatg cctatgcggt tgcttcaacg ccaacagctg atatcgcggc
    21061 aaactgggtt tggaattttg gctattttac tgttaatcgt atcggttacc aagcccaagt
    21121 tatcccagcc ttgcttgcag gtttgagtct gtcttatctt gaaatcttct ggcgcaagca
    21181 tatcccagaa gtcatttcta tgatttttgt acctttcttg tcattgattc cagccttgat
    21241 tttggctcat actgttttgg gaccaatcgg ttggacaatt ggacaaggac tttcatcagt
    21301 tgtcttggca ggtttaactg gtccagttaa atggctcttc ggtgcaattt ttggtgccct
    21361 ctacgctcca tttgtcatca caggtctgca ccatatgacc aatgccattg atacacaatt
    21421 gattgcggat gctggtggca ctgccctatg gccaatgatt gctctttcta atattgctca
    21481 aggctcagcc gtgtttgcct attatttcat gcatcgccat gatgagcgtg aggctcaggt
    21541 ttcacttcct gcaaccattt cagcctatct cggtgttaca gaaccagctc tttttggggt
    21601 taacgtaaaa tatatttatc catttgttgc tgggatgact ggttcagccc ttgcaggcat
    21661 gttatccgtt acttttaatg taactgcggc ttctattggt atcggtggtt tgccaggtat
    21721 tctctctatt caacctcaat acatgctgcc atttgcagga actatgctag ttgcgattgt
    21781 tgttccaatg ctcttgactt tcttcttccg caaggctggt ctctttacaa aaacagaggg
    21841 cgatacgaac ttgcaggcag aattcgttgc tcaagaagaa gcagaatttg tgagccatga
    21901 actagtagaa cttacttcgg tagaaattat cagcccacta actggccaag tgaaagaatt
    21961 gagtcaagcg acggatccta tttttgcatc aggtgtcatg gggcaaggtc tagtcattga
    22021 accaagccaa ggtgagttga cctctccagt taatgggaca gtgacggttc ttttccctac
    22081 caagcatgcc atcggcattg tctctgacga gggagttgaa ttgctcatcc acatcggtat
    22141 ggatacagta ggtcttgatg gcaaaggttt tgaaagtctt gtagtccaag gagatcacgt
    22201 tacagttggt cagcaactga ttcgttttga tatggatgtc attaaggctg caggtctggt
    22261 gacagaaact cctgttatca tcaccaacca agatgcttat acagcgacta ttcccggaac
    22321 ttatccgaca acgatccaag ctggagcatc tctcatggtc gctacacgaa tctaatactc
    22381 ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaac ctcaaaatag tgttttgagc
    22441 aacctgtggc tagcttccta gtttgttctt tgattttcat tgagtataat tgaaatagca
    22501 caaataggga cggaagactg cttcctccct tttatcagaa aaggagaaac agatgacact
    22561 tgataaagga aaagtagtct atcaaatcta tccaaaatct tacaaagaca ccactgaaaa
    22621 cggtattggg gatttccgtg ggattatcga aaaaattccc tatttagcca aactaggtgt
    22681 ggatatggtc tggctcaatc cattctatcc aagccctcaa cgggataatg gttacgatat
    22741 ttcagattat atggcagtgg atcctctttt tggtgatatg gctgattttg aggaaatggt
    22801 gtgtgtcggt aaagagcaca agattgactt tatgctggat atggtactta atcattgttc
    22861 gacagagcat gaatggtttc agaaagccct agctggtgat aagtattatc aagacttttt
    22921 cttcatccaa gaccaaccaa cagattggca gtctaagttt ggtggttctg catggacgcc
    22981 tttcggggat actgggaaat actatcttca cctatttgat gagacccagg ctgaccttaa
    23041 ctggcgcaat tccaatgtcc gtaaggagct tttcaaggtt gttaatttct ggcgcgacaa
    23101 gggtatcaaa ggtttccgat ttgatgtgat caatttgatc ggtaaggacg aggtttcagt
    23161 ggactgtcct gaaaatgaag ggaagccagc ttatacagac aaacccatcg ttcataacta
    23221 tttgcgtatg atgaaccaag ccacttttgg atctgacgat agctttatga cagttgggga
    23281 aatgtcttct accaccatgg aaaactgtgt cctctattcg tcgcctgatc gtcaggaatt
    23341 atccatgacc tttaattttc atcacctcaa ggtggactat aaggatggac aaaagtggac
    23401 cttggctccc tttgattttg aagagttgaa gagtctttac catagttggg gtaaggaaat
    23461 gagtgataaa gacggttgga gtgccctctt ttggaacaat cacgatcaac cacgtgcctt
    23521 gaaccgtttt gtcgatattc aaaacttccg caaggaagga gccaccatgc tagcggctag
    23581 cattcacctg tcacgtggga caccttatat ctatatgggt gaagaaatcg ggatgattga
    23641 cccagactat gattctatgg ctgattatgt ggatgtcgaa tcgcttaatg cctatcagac
    23701 gctcttagaa gaaggaaaga gtcagcaaga agccttccag attattcaag ctaagtcgcg
    23761 tgataattca cgcattccca tgcagtggga tgcttcggaa aatgcaggat tttcaacagg
    23821 cactccatgg ttgaaagctg gtaaatccta taaagacatc aatgtagaaa atgaaatcca
    23881 gggtccgatt ttcaccttct atcaagactt gattcgactg cgtaaggaaa tgccaatcat
    23941 ttcagaagga agttacaaac cagcctttga agatagcaaa caagtctacg cttttgaacg
    24001 ccagtttgag gatcaaaagt tactagtgct caataacttt tatgctaaag aagtggaaat
    24061 cgacttgcca gcagtctacc aaaatggaca gattttgata tcaaactatg aagatgcaga
    24121 agtgtctgag aaaattctac tcaaacccta tcaaacactg gctatttatg taaattaata
    24181 ctcttcgaaa atctcttcaa accgtgtcag ttttatctgc aacctcaaag cggtgctttg
    24241 agcaacctgt ggctagcttc ctagtttgct ctttgatttt cattgagtat aaacttagca
    24301 aggagacctc tttttcagaa aagcagcgtt ctttttgctg tctattccat ccctgaaagt
    24361 gtagaacaaa ctggtcaggg tggctagttt gtggtataat gaaagggatt caaaaagaaa
    24421 caggagaaaa atgatggatt tacttttagc aattgtattg attgtgctag cttttctagg
    24481 aggagctctt ggaggaatgt acttggttcg taagcaaatc gaaaaagaat ttgctgacaa
    24541 cccacgtttg aatgctgaag cagttcgtac tcttttgagt gcaaatggtc aaaaaccaag
    24601 cgaagctaag gtacaacaag tttaccacca aatcatccgc caacaaaagg cagcccttgc
    24661 taacaataaa aagaaaaaat aaataaggaa aagtctggga tgaaagttcc agacttctca
    24721 ctatgttggt tatggtttag ggatgagact ttttccttgc attctattga tatttgatta
    24781 tgattaagag agaggtagtt gacattctat caagctgtcg gtcagttcgt tcagtacaag
    24841 gaatcataat gaacgatcaa tcagaaaaaa gactagaaag aagactgtat ggataatcga
    24901 ccaattggtt ttttggattc gggtgtcggg ggcttgaccg ttgtgcgcga gctcatgcgc
    24961 cagcttcccc atgaagaaat cgtctatatt ggagattcgg cgcgggcgcc ctatggcccc
    25021 cgtcctgctg agcaaattcg tgaatatact tggcagctgg tcaactttct cttgaccaag
    25081 gatgtcaaaa tgattgtcat tgcttgtaac actgcgactg cggtcgtctg ggaagaaatc
    25141 aaggctcaac tagatattcc tgtcttgggt gtaattttgc caggagcttc ggcagccatc
    25201 aagtccagtc aaggtgggaa aatcggagtg attggaacgc ccatgacggt acaatcagac
    25261 atataccgtc agaaaatcca tgatctggat cccgacttac aggtggagag cttggcctgt
    25321 cccaagtttg ctcccttggt tgagtcaggt gccctgtcaa ccagtgttac caagaaggtg
    25381 gtctatgaaa ccctgcgtcc cttggttgga aaggtggata gcctgatttt gggctgtact
    25441 cattatccac tccttcgccc tattatccaa aatgtgatgg ggccaaaggt tcagctcatc
    25501 gatagtgggg cagagtgcgt acgggatatc tcagtcttac tcaattattt tgaaatcaat
    25561 cgtggtcgcg atgctggacc actccatcac cgtttttaca caacagccag tagccaaagt
    25621 tttgcacaaa ttggtgaaga atggctggaa aaagagattc atgtggagca tgtagaatta
    25681 tgacaaataa aatttatgaa tataaggatg accaggactg gtatgttggg tcttatagta
    25741 tttttggtgg cgttaacagt ttgagcgact atcagacaga ttttcctctg tttgaattct
    25801 ccaaaatatt tggagatgaa gagtatggtt tcccgctttc agttactgtt ttacgctatg
    25861 gttctaccta ccgtttgttc tcctttgtgg tagatatgct taatcaagaa atgggacgaa
    25921 acttggaagt tattcaacgt catggggccc tgctcttggt tgaaaatggg caactcttgt
    25981 atgtagaatt gcctaaagaa ggggtcaatg ttcatgattt ctttgagaca agcaaggtca
    26041 gagaaacctt gttgattgcg actcgtaacg aaggtaaaac caaggaattc cgagctatct
    26101 ttgataagtt aggctacgat gtggaaaatc ttaatgacta ccctgacctg cctgaagtag
    26161 cagaaacagg tatgaccttt gaggaaaatg cccgccttaa ggcagaaacc atttctcaat
    26221 taacgggcaa gatggttttg gcagatgatt ctggtctcaa agtcgatgtc cttggtggct
    26281 taccaggcgt ctggtcagct cgtttcgcag gtgtgggagc aactgaccgt gaaaataatg
    26341 ccaaactctt gcacgaattg gccatggtct ttgaactcaa ggaccgctcg gctcagttcc
    26401 acacaaccct agtcgtagcc agcccaaata aggaaagttt agttgttgaa gcagactggt
    26461 caggttatat taactttgaa cctaagggtg aaaatggctt tggctatgat cccctcttcc
    26521 ttgtaggaga gacaggtgag tcatcagctg aattaaccct ggaagaaaaa aatagtcaat
    26581 ctcaccgtgc cttagccgtt aagaaacttt tggaggtatt tccatcatgg caaagcaaac
    26641 catcattgta atgagcgatt cccatggcga tagcttgatt gtggaagaag tccgtgatcg
    26701 ctatgtgggc aaagtcgatg ccgtttttca taacggcgat tctgaactac gtccggattc
    26761 tccactttgg gagggcatcc gcgttgttaa agggaacatg gacttctacg ccggctaccc
    26821 agaacgtctg gtgactgagc ttggttcgac caagattatc caaactcatg gtcacttgtt
    26881 tgacatcaat ttcaactttc aaaagttgga ctactgggct caggaggaag aggccgctat
    26941 ctgcctctat ggtcacttgc atgtgccaag tgcttggttg gaaggcaaga tcctctttct
    27001 aaatccaggc tctatcagtc aaccacgagg taccatcaga gaatgtctct atgctcgtgt
    27061 ggagattgat gatagttact tcaaagtgga ctttttgaca cgagatcacg aggtgtatcc
    27121 aggtttgtcc aaggagttta gccgatgatt gccaaggagt ttgagacttt cttgttgggg
    27181 caggaggaaa cttttttgac ccctgctaaa aatctagctg tgttgattga tactcacaat
    27241 gcggatcatg cgaccctctt gctcagtcag atgacctata cccgtgttcc cgttgtgaca
    27301 gatgaaaaac agtttgttgg gacgattgga ctcagagata ttatggctta tcagatggag
    27361 catgacttga gccaagaaat catggcggat acggatatcg ttcatatgac aaaaacggac
    27421 gtagcggttg tttcgcctga tttcaccatt acggaggtct tgcacaagct agtagatgag
    27481 tccttcttac cggttgtgga tgcagagggt attttccaag ggattattac gcgcaagtcc
    27541 atcctcaagg ccgttaatgc cctcttgcat gactttagta aggaatatga gattcgatgc
    27601 caatgagaga caggatttca gcctttttag aggaaaagca gggcttgtct gtcaattcca
    27661 agcagtccta taagtatgat ttggagcaat ttttagacat ggtaggtgag cggatttctg
    27721 agaccagtct caagatttac caagcccagc tagccaatct aaaaatcagc gcccagaagc
    27781 gaaagatttc ggcctgtaac caatttctat actttctcta tcaaaaagga gaggtggaca
    27841 gcttttaccg cttggaatta gccaaacaag ctgaaaagaa gacggaaaag ccagagattc
    27901 tatacctaga ctctttttgg caggaaagcg accatccaga gggccgcttg ctagcgctct
    27961 taatcctaga aatggggctc ttgcccagtg agattttagc catcaaggtt gcggacatca
    28021 atctggattt tcaggtgttg cgaatcagca aggcttccca acggaggatt gtcaccattc
    28081 ccacggcctt gctttcagaa ttggaaccct tgatggggca gacctatctt tttgaaagag
    28141 gagggaaacc ctattctcgt cagtgggcct ttcgtcagtt agaatctttt gtcaaggaga
    28201 aaggttttcc atccttatca gctcaagtct tacgtgaaca gtttattcta agacaaatag
    28261 aaaacaaggt cgatttgtac gaaattgcaa aaaaattagg attaaaaaca gtcctgacct
    28321 tagaaaaata tagataatgg atattaaatt aaaagatttt gaaggacccc tggacttact
    28381 cttgcatctg gtttctaagt accagatgga tatctacgat gtgcccatta cggaagtcat
    28441 cgaacagtat ctagcctatg tctcaaccct gcaggccatg cgtctggaag tgacgggtga
    28501 gtacatggtc atggctagtc agctcatgct gattaagagt cgtaaactcc ttccgaaggt
    28561 agcagaagtg acagacttgg gggatgacct ggagcaggac ctcctctctc aaatcgaaga
    28621 atatcgcaag ttcaagctct tgggtgagca cttggaagcc aagcaccaag aacgggccca
    28681 gtattattcc aaagcgccga cagagttgat ttacgaagat gcggagcttg tgcatgacaa
    28741 gacgaccatt gacctctttt tggctttttc aaatatccta gccaagaaaa aagaggagtt
    28801 tgcacaaaat cacacgacta tcttgcggga tgagtataag attgaggaca tgatgattat
    28861 tgtgaaagaa tccttgattg gacgagatca attgcgcttg caggatttgt tcaaggaagc
    28921 ccagaatgtc caagaggtca tcaccctctt tttggcaacc ctagagttaa tcaaaaccca
    28981 ggagctgatc ctcgtgcaag aggagagttt tggagatatc tatctcatgg aaaagaagga
    29041 agaaagtcaa gtgcctcaaa gctagacttg atagagagga aagatgagta ctttagcaaa
    29101 aatagaagcg ctcttgtttg tagcgggtga agatgggatt cgggtccgcc agttagctga
    29161 actcctctct ctgccaccga caggcatcca gcaaagttta ggaaaattag cccagaagta
    29221 tgaaaaggac ccagattcca gtttggcttt gattgagaca agtggtgctt atagattggt
    29281 gaccaagcct caatttgcag agattttgaa ggaatactct aaggcgccta tcaaccagag
    29341 cttgtctcgg gctgcccttg agaccttgtc cattattgcc tacaaacagc cgattacgcg
    29401 gatagaaatt gatgccatcc gtggggttaa ctcgagtgga gccttggcaa agttgcaagc
    29461 ttttgacctg ataaaggaag acgggaaaaa ggaagtattg gggcgcccca acctctatgt
    29521 gactacggat tatttcctag attacatggg gataaaccat ttagaagaat taccagtgat
    29581 tgatgagctt gagattcaag cccaagaaag ccaattattt ggtgaaagga tagaagaaga
    29641 tgagaatcaa taagtatatt gcccacgcag gtgtggccag taggagaaaa gcagaagagc
    29701 tgatcaagca aggtttggtg acggttaacg gccaagtggt gcgtgaacta gcaaccacta
    29761 tcaagtcagg cgacaaggtc gaagttgaag gtcaacctat ctacaacgaa gaaaaggtct
    29821 attatctgct taacaaacca cgcggtgtca tttccagtgt aacagatgac aagggtcgca
    29881 agacggttgt cgacctcttg cccaatgtca aagaacgtat ttaccctgtg ggtcgtttgg
    29941 actgggatac atcgggtgtc ttgattttga ccaatgatgg ggactttaca gacgagatga
    30001 ttcaccctcg taatgagatt gacaaggttt atgtcgcgcg tgttaaaggt gtggccaata
    30061 aggacaatct ccgccccttg acccgtggtc ttgagattga tggtaagaaa accaagccag
    30121 ctgtttatga aattctcaaa gtggacccag tcaaaaatcg ctctgtggtg cagttgacca
    30181 tccatgaagg gcgtaaccat caggttaaaa agatgtttga agctgttggt ctccaagtag
    30241 ataagttgtc tcggactcgt ttcggacacc tagacttgac aggactccat ccaggagaat
    30301 cccgtcgtct taataaaaaa gaaatcagcc aactacacac catggctgta actaagaaat
    30361 aatgaaacga attttaatag cgcctgtgcg cttttaccaa cgttttatct caccagtctt
    30421 tccaccctct tgtcgctttg agctgacttg ttccaactac atgattcagg ctattgaaaa
    30481 acatggtttt aagggggtat tgatgggctt ggctcggatt ttacgttgtc atccctggtc
    30541 gaaaacaggt aaggaccccg ttccagacca cttttccctt aaacgaaatc aagaagggga
    30601 atgaggtggg gtaaatagat ttcaaaatga taaaaacgca tcctatcagg tttgagtaaa
    30661 cttgatagga tgcgttttag aatgtcaaaa ttttatactc ttcgaaaatc tcttcaaacc
    30721 gcttcagctt tcatctgcaa cctcaaaaca gtgttttgag caacctgcgg ctagtttcct
    30781 agtttgctct ttgattttca ttgagtatta aattgagttt gaagtggctt atttcaaagc
    30841 tttttgtatg tcttcaatca tgagttttgt tgattcaagt ccgcctccgc ttagatacca
    30901 gaggtctggt gttagttgga taatcttacc atttttagca gcaggtgttt cagcgataag
    30961 ggcattttct aggacaccgt cgttgctaga gttgtcccca ccgatggcaa gggtacggtt
    31021 gatgacaaag aggatgtcag ggttgatttc tttgacactt tcaaagctga cttcttgtcc
    31081 gtggcgtgag tcttcaaatt ttgtatcagt tggtttgaat ttcaaggttt ggtacaagaa
    31141 agagaaacga gatttggcac caaaggctgc catttttcct tcattaagga ggatcgcaag
    31201 ggcttttttg tcagagcttt catttttagt agcgacttct tggatgctct tgtctagctt
    31261 ggccaattct tccttggctt tctgtgtacc agtttcgccg aaggcacttg ctaaggattc
    31321 gatattagcc ttggtagaag tccagtagtc gtccttgctt gcttggaaga gaacggttgg
    31381 ggcgatttct ttgaatttgt ctacgaattt ttgtgtacgt ggtgaagcga taatcaaatc
    31441 aggctcaagg gcggcgatag cttctaaatc aggttctttc atagaaccaa catttttgac
    31501 agttcccact aggtctttta gataagtcgg aacagttttt gtaggcattc cgacgatatt
    31561 tttttcaaat cctaaagcgc gaatagtatc cgcaacgccg aggtcaaagg tcacaatctt
    31621 ttcaggaact ttggaaagtt tgacctcgtc cagtgaactt ttaatggtta cctctgttgg
    31681 agcagagcta ctggtctctg tctgactagt gcttgagttt gtactacatg caccaagtag
    31741 gagcaagaag ctggccacta gggcagtgaa ataaagttta agggatgttt tcataatttc
    31801 tcctttttaa aatgtgataa cgatttaggg agtctcttga tcttattgac taagagactg
    31861 aaggttctct aacttgagct tttatgttac tagctataga tacagatctt tttgtcattg
    31921 atatcagcta gcgtgatggg aatctcataa agttgactga gtaggtcagc ctgcatgatt
    31981 tgatcggttc ttcccttgct aaagacctgg ccgtccttga aggcgacaat ttcatctgca
    32041 tactgactgg ccatgttgat atcgtggagg acgatgataa tggtcttgcc gagttcctcc
    32101 accagtcgtc gaagaatctg catcatgctg acgctttgct tgatatcgag attgttgagt
    32161 ggttcgtcca gcaagataaa gtccgtatcc tgggccagta ccatagcgat aaagacgcgc
    32221 tggagttgcc cccctgacag gctattgatg tagcggtctt ttaagttggt cagttccaaa
    32281 tagttcagag tttctcggat tttttcccag tcttctgatc taagtcgacc tcggctgtag
    32341 ggaaaacgtc caaaactgac cagttcttca acagtcaatt tggcttggta attgattttc
    32401 tgttttagga tggttagttc ttgggccagt tcttgcgaat tccagctctc gatttcacgt
    32461 cctttgatac tgagaactcc ctgatctttc ttggttagtc tgctcatgat ggagaggaga
    32521 gtcgattttc cagcaccatt tggaccaata aaggctgtca gtttttgagg actgacttca
    32581 agcgaaatgc cttgcaaaat atcctgtttt tgaatggatt tgtcaatgtt ttccagtttc
    32641 actgacgaga cctcctatat agtaagataa agaataagaa gccacccaca ctctcaatga
    32701 tcatactgat acgaatttcc agtgcaaaga ctcgttcaat caaggcttgc cccaaggtta
    32761 agctaataaa tccaatcaga atggccacta taaagagtaa cttgtgctga tagtctttga
    32821 caatcaggta ggtgaggttg gccagcataa agccgaagaa ggccataggt cctaccaagg
    32881 cagtggccgt tgaggtcaaa agcacgattc cccagaggag ctctttctgt tctttttcaa
    32941 catcgagtcc caatatctga gccgtttctc tttgcaggtg caagacatct agaacgactg
    33001 cttttcgaaa gaaaaagatt gtcaaagcga ggatgatcag agaaccgatg gctaggatgg
    33061 aagtgttgag atgttgaaag gaggcaaaaa gactattttg cagtttatcg tattcgtttg
    33121 gatccattag gacttgaagg aaggtgctga tatttcgaaa gagacttctg agcgctagac
    33181 agatcagcag gatgaagacc aggtcttgct tcatcagtgt cttcaagtaa ccttgtaagg
    33241 cgagaaagaa gagggactgg acaagaagta agactaggaa ttctaagata ggggatttgc
    33301 caagttgaag aaacttgctt tcaaaaacca gtagtagggt ttgtagtagg acgtagaagg
    33361 attcaattcc caaaatacta ggcgtcagga agcgattttc cgtcagggtt tgaaaactaa
    33421 tggtcgaaat cccagtcgcg atggctacca agagataaac gatgatcttt tgggaacgca
    33481 acttccaagc aaaggctgac aagtgagtga tgggccaaaa gtagagaaga caagctccga
    33541 tggcaagaat aatgagaatc cagaagagct tggtatgttt gcttttagtc tgcatctttt
    33601 cgtccccctc tccagagaag taggataaag acgagactac cgatgattcc tagcaagaga
    33661 ctgacagaca actcataggg cctaatcaga actcgggata ggatatcgca agccagaact
    33721 agattggcac caaccagtgc gaccatgagt ttggtttgac ttagattatc tccatagcac
    33781 ttgcgaacaa gattgggaac gataactccg agaaatggta ggccacccac ggtaatcatg
    33841 gtgacgcttg tcgttagcgc caccagaaag agggccagtt tttcaagtag ggagtaggaa
    33901 atccccaaac tctcgctggt ttctttccct agattcatga tggtgaaggt ttgggataat
    33961 ttccaaacgg ttatcaggat gatgaggcct aagaagagcc actcatactg atgggtctga
    34021 atcatggaga aggagccctg ggtccaggca gtcatactct gaaccagatt gaaacgatag
    34081 gcgataactt ctgtgactga gccgataatc ccgctataga tgatcccaat cagaggcaac
    34141 atccaccttt cctttacagt aaaaatggtc ataaaggcta ggaagaagag ggtgaatacg
    34201 atggatgaaa caaaagcgaa gagcatcttt tgggtcagac tagccgatgg aaagacaaaa
    34261 aggctcagca ccattcccag tttggcggct tcagtcgttc caactgtact cggtgcagca
    34321 aactgatttt gggtaatagt ctgcatgaga aggcctgcca tactcatact agaggcagtc
    34381 aggagaatac tgatagttct tgggagacgg gactcttgaa agaggagcca ggtctgctgg
    34441 tcgaaatcaa atagctttcc ccatgaaaaa tcactggtcc caatgctaat agagagaaag
    34501 actaggagta gaagtaagcc aattaaataa tgagaaagtt tcataccccg tcctttcatg
    34561 tagatttggt atcgaaagat atctgcggat ataaatgtaa cattattttt ctaatctgtc
    34621 aataaaattt ctgacaattt aataaataca acaaggagag agcaacaaga ctttctcctt
    34681 tgttatccta ttctaaaatg tttttacctt aatctgataa aataatatct tcgagggagt
    34741 agctagccgt ccaatcaaga tattgtttag cttttgaagc atctgctagg acactggctg
    34801 ggtcactagc acgtcgagca acaatctcgt gtgggatttt ttaatttagt aattcttcag
    34861 cagttttaaa gatttctttg atagtatagc cttttttagt tcctaagtta aagatttgag
    34921 aagaactgtc ttcttgaaat aggtagttca ttcctttaac atgagcctat gcaaggtcca
    34981 agacataaat gtaatctcga atacatgaac cgtcacgtgt atcgtagtca tctccaaata
    35041 tttttaagct atcattttgt cccaatgcgg tcttgttgat atttggaatg atgtgagttg
    35101 gatttttcac acgcagaccg tttgaagcat ccatttcagc cccagcaaca ttaaagtaac
    35161 ggaaaataac atatttccag tcgtagcgat tggccatcca gtaaatcatt cgttcgccca
    35221 tcagttttgt ctctgcataa gggttgacag ggtcgagcag ggtatcttca gtcaccggct
    35281 tgtcaataca gttatttcca tagagagaag cagtcgaaga gaacatgatt ttttgaatgc
    35341 caacttcaga taagactttg agaacttggt tcataccagc aacgttggca gtgaagtatt
    35401 tacttggatt ttcaatactt tcgctcacaa caatttcacc tgcacaatgg aggacagcat
    35461 caatctgatt ttcttttaag taagccttta aggcgctagc atcataaaca tccagttctt
    35521 taaagctagc acgactatcc acagccgctc gatttcctgt ggagagatta tcgaggacat
    35581 gcaccttata gccagcattt aaaagagctt taacggtatg ggagccaatg tagctagtcc
    35641 cacctgtaac aagaattgtt ttggtcatga ttttttcctt ttctagtttt gtactatagt
    35701 aaattgaaat aagatatgaa caactctatt aggaaagtca aattaatttc tagaaatgtt
    35761 ttagcagcta cagcgtacta ttccaaactc aaccaactat atatttaaag aaagaagaaa
    35821 gggaagtcaa ctattttctg taaatttcat gaaaaatcca aacaactttg atggtgtatt
    35881 gttttttgtt tggaaataaa tattcgagtt aattttggaa tgtttactag attttgcact
    35941 acatgcaaga gaatactatc cttttctaag atagagcagg actaagatac taacttagaa
    36001 atccaccttc ccactatcct tctcctataa aaagtggtaa aatggatgaa agaaagaagg
    36061 aactgaaatg acaacattat tttcaaaaat taaagaagta acagaacttg ctgcagtctc
    36121 aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag ttgacaccgc atgtggatga
    36181 agtggtgaca gatggcttgg gtggtatttt tggtatcaaa cattcagaag ctgtggatgc
    36241 accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt tttatggtca gcgaaatcaa
    36301 gccagatggt accttccgtg tcgtagaaat cggtggctgg aaccccatgg tggttagcag
    36361 ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt cctgtgattt caggttctgt
    36421 tcctccgcat ttgactcgtg gaaagggggg accaaccatg ccagccattg ccgatatcgt
    36481 ttttgatggt ggttttgcgg acaaggctga ggcagaaagt tttggcatcc gtcctggtga
    36541 taccatcgta ccagatagtt ctgcaatttt gacagccaat gaaaaaaata tcatctcaaa
    36601 agcttgggat aaccgctacg gtgtcctcat ggtaagcgag ctagctgaag ctttatcagg
    36661 tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc caagaagaag ttggtctgcg
    36721 tggcgctcat acctctacaa ccaagtttga cccagaagtc ttcctcgcag ttgattgctc
    36781 accagcaggt gatgtctacg gtggtcaagg caagattgga gatggaacct tgattcgttt
    36841 ctatgatcca ggtcacttgc ttctcccagg gatgaaggat ttccttttga caacggctga
    36901 agaagctggt atcaagtacc aatactactg tggtaaaggc ggaacagatg caggtgcagc
    36961 tcatctgaaa aatggtggtg tcccatcaac aactatcggt gtctgcgctc gttatatcca
    37021 ttctcaccaa accctctatg caatggatga cttcctagaa gcgcaagctt tcttacaagc
    37081 cttggtgaag aaattggatc gttcaacggt tgatttgatt aaacattatt aaaccataag
    37141 ggaggtggta gggatggcag aaccaaacct agaaagcctt ataaaagatc tttacaatca
    37201 tgctcgacat gatttgagtg aagatttagt tgctgctctc ctagagacta ctaaaaaact
    37261 gcctactaca aatgagcaat tgcaggcagt tcgtctctca ggcctggtca atcgtgaatt
    37321 gctcctaaat cccaaacatc cagcacctga gttgctcaac ttggctcgct ttatcaaaag
    37381 agaagaagcc aagtacagag gaactgcgac ttctgcactt atgtatgagg aactttttaa
    37441 aatgctttga ttccattgtg gatcaaagca ttttttataa gacctatctc gtgagcgttc
    37501 aaatagtagt aacaaggaat catgagaagt cagccgagac catagtagtg aagaaacttc
    37561 tgtaatggaa gtggagtgaa gtgaggaatc gtcaaacggt aggggatagg ctgtttgaag
    37621 ggtgctacga aaaagatagg gtaaggtgaa attatagcgg aatgaaataa gatatgaaca
    37681 aattgattag ggaaatcaaa tgaatttata gaaatctttt agcagtcatg gtgtcctatt
    37741 ccagtttcga aatgctataa agacgaacaa attgattggg aaattcaaat cgctttctat
    37801 caatgtttta gaagatacag tgccctagtc caacttcaat atactataaa agaacagatg
    37861 gaagcaatta tgatttactt ctatctttaa aataaatgat ctgataggaa aaatgtgtcc
    37921 cctcataaaa aataggatag tacggatgga aggcttttgt agactggagg acgaaggaat
    37981 ttagaaactc tcgttaaaag ttagttgagc cggagtatgg tggtgtgaat aattatcaaa
    38041 aattatttcc aaatcgaaat agttgacagt tagaacgatg agtgttacaa ttattttatt
    38101 catttcgaca tcgaaataaa ttggaggtgt tatgaaagat agtcatttgc tagcccatca
    38161 tattcgtttg ttgaatgggc ggatttttca aaagttactg agtcaagatc ctgaggctct
    38221 ttataggggt gaacagggca agattttagc ggttttatgg aatagtgaaa ctggctgcgc
    38281 aactgcgaca gatatcgcgc ttgcgactgg acttgcgaat aatacgctga cgactatgat
    38341 aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg tgtggaaaag acaagcgtaa
    38401 gaagtattta gttttaacgg agttaggcaa gtcccagaaa gaagtggggc atcgtgtcag
    38461 tcagaaattg gatactatct tttacaaagg attttcagag gaagaaattc accaatttga
    38521 aggttttcaa gaaagaattt tggcgaatct gaaagagaag ggaaatgagg tttagaatat
    38581 gtcacaacaa gtgaaaaatg ctcacaacct atacatccat gccattcaag acggacgagt
    38641 tgctgaggct caagcccagt ctgtagggga tacctatatc caacattcga caggtgttcc
    38701 tgacgggaaa gaaggatttg cagccttctt tgcagatttc tttgagcgtc atccagagcg
    38761 tcagattaag attgtccgca tcattgagga tggcaatctg gtctttgttc atgttcatca
    38821 atatctgaat ggtggagaag ctcaatgggt gacgacggat actttccgtg cggatgagaa
    38881 tggtcgtatt gttgagcatt gggatgtcat tgactactat cgaacacctg aaaatgacca
    38941 actagatcaa atttttggag attttgaaat caaggatttg gacaagaaag cagaaaataa
    39001 aaagctggtt cgccgtttct tgacagaaat tttccaaaat ggggagctag agcagtggag
    39061 tgattatgtg gcagacgatt tgattcagca taatcatgag attggacaag gaagtgctgc
    39121 ttataaaaac tatgtggctg aatatagtgt cacttttgac tttgttttcc aactcttagg
    39181 acaaggaaac tatgtggtta gctatggtca gactcagatt gatggcgttg cttatgccca
    39241 gtacgatatc ttccgtttag agaacgggaa aattgtggag cattgggata ataaggaagt
    39301 catgcctaag gtagaagact tgaccaatcg agggaagttt taaattgagg acaaagaatg
    39361 attgaataca aaaatgtagc actgcgctac acagaaaagg atgtcttgag agatgtcaac
    39421 ttacagattg aggatgggga atttatggtt ttagtagggc cttctgggtc aggtaagacg
    39481 accatgctca agatgattaa ccgtcttttg gaaccaactg atggaaatat ttatatggat
    39541 gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc tttctactgg ttatgtttta
    39601 caggctattg ctctttttcc aaatctaaca gttgcggaaa atattgctct cattcctgaa
    39661 atgaaggggt ggagcaagga agaaattacg aagaaaacag aagagctttt ggctaaggtt
    39721 ggtttaccag tagccgagta tgggcatcgc ttacctagtg aattatctgg tggagaacag
    39781 caacgggtcg gtattgtccg agctatgatt ggtcagccca agattttcct catggatgaa
    39841 cccttttcgg ccttggatgc tatttcgaga aaacagttgc aggttctgac aaaagaattg
    39901 cataaagagt ttgggatgac aacgattttt gtaacccatg atacggatga agccttgaag
    39961 ttggcggacc gtattgctgt cttgcaggat ggagaaattc gccaggtagc gaatcccgag
    40021 acaattttaa aagcgcctgc aacagacttt gtagcagact tgtttggagg tagtgttcat
    40081 gactaattta attgcaactt ttcaggatcg ttttagtgat tggttgacag ctctatctca
    40141 acatttgcag ttgtcacttt tgaccttgtt actagctatt ttgcttgcga ttcccttggc
    40201 tgtttttctt cgctatcatg agaagctggc cgactgggtc ttgcagattg caggtatttt
    40261 ccagaccatc ccgtctctgg ccttgttggg gctctttatc cctttgatgg gaattgggac
    40321 cttgccggct ttgacagctc tagtgattta tgcgattttc cctattttgc aaaatactat
    40381 cactgggctg aagggaattg atccgaacct gcaagaggct gggattgcct ttgggatgac
    40441 cagatgggaa cgtctcaaga aatttgaaat tccactcgcc atgcctgtta tcatgtctgg
    40501 gattcggacg gcagctgttt tgattatcgg tacggcaacc ttggcggcct tgattggagc
    40561 agggggactg ggttccttta tcctgttggg aattgaccgt aataatgcca gtttgatttt
    40621 gattggggca ctttcttctg cagtgcttgc tattgccttt aacttcctac taaaagtaat
    40681 ggaaaaagca aaattacgga cgattttctc aggttttgcc ttggtgacgg tattgctggg
    40741 tctatcttat agtccagccc tcttggttca aaaagagaaa gaaaacgtga ttattgcagg
    40801 gaaaattggt ccagaaccag aaattttggc taatatgtat aaacttttaa tagaagaaaa
    40861 tacaagtcta acagcaaccg ttaagcctaa ctttgggaaa acaactttcc tttatgaagc
    40921 gttgaaaagc ggagacattg atatctatcc tgaatttact ggtacggtga ctgaaagttt
    40981 gcttcaacca tcacctaaag tgagtcatga gccagagcag gtttatcagg tggcgcgtga
    41041 tggcattgcc aaacaggatc atctagccta tcttaaaccc atgtcttatc aaaatactta
    41101 tgctgtagct gttccgaaaa agattgcgca agaatatggc ttgaagacca tttcggattt
    41161 gaaaaaagtg gaaggtcagt tgaaggcagg ctttacactc gagtttaacg accgtgaaga
    41221 tggaaataag ggcttgcaat caatgtatgg tctcaatctc aatgtttcaa ccttggaacc
    41281 tgctcttcgc tatcaagcga ttcagtcagg tgaaattcaa attacagatg cctattcgac
    41341 tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa gatgacaagc aactcttccc
    41401 accttatcag ggggcgccac tgatgaaaga agctcttctc aagaaacacc cagaattgga
    41461 aactgttctt aataaattgg ctggtaagat tacagaaagc cagatgagcc agcttaacta
    41521 tcaagtcggt gtcgaaggca agccagcaga acaagtagcc aaggaatttc tacaagaaca
    41581 aggtttgttg aagaaatgat gggacagaga ctttaaacat actgaactca acttccttaa
    41641 acgactagat aaaagaatgc tcagacaatt tcgtctgggc ttttttgatg tgagaatgac
    41701 tgaatgtcac ttaaaatgga aagaaagaga aaattttcat gattttctaa aattttactg
    41761 taaagacagt tgactattca taaaataggt gtataatatt ttgtgaacta cttaacaaat
    41821 aagaggtttc agctcatgtc gactaaggtt agaaatcttg tgtataggca gttcattatc
    41881 taatagagcg ttgcgtccga aagtctatcc agacacggct ctttaaaaac aaaaggagaa
    41941 atgatgcata cttatttgca aaagaaaatt gaaaatatca aaacaaccct aggtgaaatg
    42001 tcaggtggtt accgtcgtat ggttgcggct atggctgatt taggattttc aggaactatg
    42061 aaggctatct gggatgacct ctttgcccat cgtagttttg cccagtggat ttatttgctg
    42121 gttttaggaa gttttcctct ctggctggag ttggtttacg aacatcgtat tgttgactgg
    42181 attgggatga tttgtagctt gacagggatt atctgtgtaa tctttgtatc ggaaggtcga
    42241 gcaagtaatt atctttttgg cttgattaac tctgttattt accttatttt ggccctacag
    42301 aaaggctttt atggtgaggt gctgacgaca ctttacttca cagtcatgca gccaattgga
    42361 cttctagttt ggatttatca ggcacagttt aagaaggaaa agcaggagtt tgtcgcgcgt
    42421 aaactggacg gcaagggctg gacaaagtat ctttccatta gtgtgctttg gtggttggcc
    42481 tttggcttca tttatcagtc tattggtgcc aatcgtccct atcgtgattc aatcacagat
    42541 gcaaccaatg gggtagggca aatcctcatg acagctgttt accgtgaaca gtggatattc
    42601 tgggcggcta ccaatgtttt ttcaatctat ctctggtggg gagaaagcct gcaaattcaa
    42661 gggaaatatc taatttatct cattaacagt ctagttggtt ggtatcaatg gagcaaggca
    42721 gctaagcaga atactgattt acttaactag gaaaagatgt ttgaaagtgc tgttttgaga
    42781 tttcgattaa aacagatata gttgataatc aaggatttat agtatgaaaa agaggatcgg
    42841 cgggtcctct tttgttgttg aaaagataaa aaactcagta atctagaaat aagacaactg
    42901 agctttactc tatattcaat ttttaggaat gagaaggtct agataaaatt ggacaacttc
    42961 ctggtctgtg aaatcttgac cttttttgag ccaccaggtc aatgtctcga taaagttgga
    43021 catgaccaag tgttggaggt aagaagtagg cagattaggg tgggcttctt ttaaattatc
    43081 agctagcacg gaatagacat ggtgttctag ctctttatgg agttgacgga ggaagtagtc
    43141 atttttggaa aatagcagac tggtgatatg gtcttggttt ttatgaaaat gcagaaagag
    43201 gtgggcgagg tagtcctcgg ttgaaatggc ttgctctctt tcaaaaagat gatggaagag
    43261 gtagcggcag agctggtcca gaagaagctc cttactctca tagtgacagt aaaaggtgga
    43321 tcgtcccaca tctgcgagat caatgatatc ctgaacagta gtggcctcgt agcccttagc
    43381 attcaaaagt tgtataaaag cttgatagat ggcttttttg gttttgctga tacggcggtc
    43441 aatgttagtc atatggacac ttgaggcaaa ttgttcagaa ctgaataaag ctgacgtttt
    43501 gcttctatcc tttctttgag ttttagtgga taatgataat gaacaaggtg ttcataaatc
    43561 tattataaca aaggaatgag aaatatgaag gcaaaatatg ctgtttgggt ggcttttttc
    43621 ttaaatttga cttatgccat tgttgagttt attgcaggtg gagtatttgg ttctagcgct
    43681 gttcttgctg actctgtgca tgacttggga gatgcgattg caattggaat atcagctttt
    43741 ctagaaacaa tctccaatcg tgaagaagac aatcagtaca ccttgggcta taagcggttt
    43801 agcctgctag gagccttggt aacagctgtg attctcgtaa cgggctctgt tctagtcatt
    43861 ttggaaaatg tcacgaagat tttgcatccg caaccagtca atgatgaggg gattctctgg
    43921 ttaggaatta ttgcgattac tatcaatctg ttagcgagtc tggtggttgg taagggaaag
    43981 acaaagaatg agtctattct gaatctgcat tttctggaag atacgctagg gtgggtagct
    44041 gttatcctga tggcgattgt tcttcgattt acggactggt atatcctaga tcctcttttg
    44101 tcccttgtca tttctttctt tattctttca aaagcccttt cacgtttttg gtctacactc
    44161 aagattttct tggatgctgt gccagaaggt cttgatatca agcaagtaaa gagtggcctg
    44221 gaacgattgg ataatgtggc cagccttaat cagcttaatc tctggactat ggatgctttg
    44281 gaaaaaaatg ccattgtcca tgtttgtcta aaagaaatgg aacatatgga aacttgtaaa
    44341 gagtctattc gaattttcct aaaagattgt ggttttcaaa atattaccat tgaaattgat
    44401 gctgacctag aaactcatca aactcataag cgaaaggtgt gtgacttgga acggagttat
    44461 gagcatcaac attagaaaaa agtgaaaaat acttgggtac tatcttattt ggaatagagt
    44521 aatttcttta ttatttaaat atttcaaaaa ttggtaagag aagagcattg tataaactcc
    44581 agatatatga ttgttaatga taaaaatttt tcgattagat acaaaatgct tgacttggag
    44641 tcaactcaaa gttatataat aagataagtg agttagaata gcgtgaactc agtgaatgaa
    44701 atgagaggag gttagcgtgt gaatattaaa tctgccagtg atttgttggg aatttcagcg
    44761 gatacgattc ggtattatga acgggttggt cttgtgccac cgattactcg tactgctact
    44821 gggattcgtg attttcaaga tcaggatatc gaagcgctgg aatttattaa gtgttttcgt
    44881 tcggcgggtg tctctgtaga tagtttagtt gactatatgt cgctctacca aaagggagat
    44941 gaaacgagag aggagaggct tggtatttta gaagaggaaa agcaaaaatt agaggagcgc
    45001 ttgtctcagc tacagacagc tttaaatcgt ttaaatctca aaattaaact ttataaggaa
    45061 ggaaaatttt aaatgaaatc agcagtatat acaaaggcag gtcaggttgg acttgctagc
    45121 attgaacgtc cgcaaataat agaagcggat gatgtgatta ttcgtgtggt tcgtgcgtgc
    45181 gtttgtggtt cagatttatg gaggtaccgt aatccagaaa cgaaagctgg acacaaaaat
    45241 agtggacacg aagcgattgg gattgttgaa gaagctgggg aagccattac gacggtgaaa
    45301 ccaggtgatt ttgtgattgt cccttttaca catggatgtg gtgagtgtga tgcctgtctt
    45361 gctggatttg acggttcttg cgacaatcat attggcaata atttgggggg tgattttcag
    45421 gcagaatata ttcgcttcca ctatgcaaac tgggcgctgg ttaaaatccc tggtcaacct
    45481 tctgactata cagaagggat gctcaagtcc cttttgactc ttgcagatgt catgccgaca
    45541 ggctatcatg cggcgcgtgt tgcaaatgtt caaaaagggg acaaggttgt tgttatcggt
    45601 gatggggctg ttggtcaatg tgctgtcatc gcggctaaga tgcgtggagc atcacaaatt
    45661 atccttatga gccgtcatga agaccgtcaa aagatggcta tggagtcagg tgcgacagct
    45721 gttgttgcag aacgtggtca agaaggaatt accaaggtgc gtgaaatcct cggtggagga
    45781 gcagatgcag catttgaatg tgttggtacg gaggctgcta tagaacaggc gctaggtgtt
    45841 cttcataatg gagggcgtat gggctttgta ggagtcccac actataataa tcgtgctctt
    45901 ggttcgacat ttatgcaaaa tatctctgta gcaggtgggg cagcttctgc tacaacatac
    45961 gataagcaat ttttactaaa agccgtcctt gatggtgata tcaatccagg tcgcgtcttt
    46021 acttcaagtt ataaactgga agatatcgac caagcctaca aagatatgga tgaacgtaag
    46081 accattaagt ctatgattgt aatcgaataa aaaacgaata ggagttctaa aactcctatt
    46141 cgttttttat gttatcctat tcttgattta gggtactttc tcttaatgtc agtctggttc
    46201 ccagcatggt caggctaggg attttccgac cgtggaggac ttccttgtta agaatatcca
    46261 tacctgctcg gcccatttct tcagtataaa ctgtaatact agagagggga ggatagacct
    46321 gtttggtcag actagtgtcg ttaaaggaaa tgaggctgac gcgatctggc aggttgattc
    46381 cagcttcttg gagggcacgg agggcaccga tagctaaact atcgctggct gcgaaaaatg
    46441 ctggcggaag ttggtctccc aagctctgaa tggcctcctt cattaagtca tagccagact
    46501 gggcagtaaa tcttccttga aagaccagtt catcatgata gattcccctc gcttgactgt
    46561 agtttctgaa attttccagc cgcttatcct caatgatttc ttcttggtct gttgtttctt
    46621 caaggcctgt tagaatcccg atacggtcca ttccttggct gaggaaataa tcgacaacct
    46681 gtttcatagc agtgtaaaaa tccgtgataa tacaggtatg tcccagggaa agtgtatcgc
    46741 tgtctagaaa tacaagaggc ttttggtatt cttcaaaggc agaaatctga gctcgactaa
    46801 actttccgat gcagagaatc ccaatcactt cctcgcttag ggtaaaaggg tggtcattaa
    46861 aatagcgcaa gatatcgtag tccaactctt gggctctttt ttctattcct aggcgaatct
    46921 ggtagtagta gaggtcgtct agctcccctt gttcgctgac ccattgaata atggcaatct
    46981 tttgcttggg tttatgggac tcgcctgtct tgaggtgctt ggtgtagccc agctcttcag
    47041 caacggttaa aatacggtgt ctggtttctt ctgtaacaga taggctctgg tcgcggttga
    47101 gaacacggga tacggtcgcg atagagacag aggctagctg tgcaatgtct tttaaggtag
    47161 ccataaatcc tccttgatta ggttagtata tcatattttt ctgcttttta ctgatatttt
    47221 agtaaaattt tagtaaaaag gattgacctt gggaaatccc ttggatacaa tagaagaaaa
    47281 cgattacacg ttaaggtggc ttaacggaca gtcaaaggag aaatcatatg acacaacatc
    47341 ttactgctga aactcttcgc aaagactttc ttgctgtttt tggtcaagaa gcagaccaaa
    47401 ccttcttttc accaggtcgt atcaatttga ttggtgaaca cacagactac aacggtgggc
    47461 acgtttttcc agctgctatt tccttgggaa cttatggtgc agctcgcaag cgtgaagacc
    47521 aagttttacg tttctactca gctaactttg aggacaaggg cattatcgaa gtgcctctcg
    47581 ctgacctcaa gtttgaaaaa gagcacaact ggaccaatta tccaaaaggt gtccttcatt
    47641 tcttgcaaga agctgggcac gtgattgaca aaggttttga tttttatgtt tatgggaata
    47701 taccaaatgg tgctggtttg tcttcttcag catccttgga gctcttgaca ggagtcgtgg
    47761 cagagcatct ctttgattta aaattagagc gtctcgattt ggttaaaatc ggaaaacaaa
    47821 cagaaaacaa ctttatcgga gtcaactctg gtatcatgga ccagtttgct attggtatgg
    47881 gggctgatca acgtgctatt taccttgata ccaacacctt agagtatgat ttggtgccac
    47941 ttgatttgaa ggacaatgtc gttgttatca tgaacaccaa caaacgccgt gaattggcgg
    48001 actctaaata caatgaacgt cgtgctgagt gtgaaaaagc agtggaagaa ttgcaagttg
    48061 ccttggatat tcagaccctg ggtgaattgg acgagtgggc cgttgaccaa tatagctatt
    48121 tgattaaaga tgaaaatcgt ttgaaacgtg ctcgccatgc tgtgcttgaa aaccaacgta
    48181 cccttaaagc tcaagcagcc cttcaagcag gtgatttgga aacatttggt cgtttgatga
    48241 atgcgtcaca cgtttctctg gagcatgatt atgaagtaac tggtttggaa ttagataccc
    48301 ttgttcacac agcttgggca caagaaggag ttctcggtgc tcgtatgaca ggggctggtt
    48361 ttggtggctg tgccattgcc ttggttcaaa aagatactgt tgaggccttt aaggaagctg
    48421 taggcaaaca ctacgaggaa gtagttggat acgctccaag cttctatatc gctgaagttg
    48481 caggtggcac tcgcgtcctt gactagtcaa aaggaggctc tatagtgacc ttagtagata
    48541 aatttgtaac acatgtcatt tctgaaagtt catttgagga aatggatcga atctacctga
    48601 ccaatcgtgt tttggcacga gtgggagaag gtgttttgga agttgagacc aatctggata
    48661 aattgattga cctcaaggac cagctagttg aggaagccgt tcgattagag acgattgagg
    48721 atagtcagac tgcgcgtgaa atccttggta ctgaattgat ggacttggtg actccttgtc
    48781 cgagtcaggt caatcgtgac ttctgggaag cctatgccta ctctcctgag caagcgatag
    48841 aggattttta tcaactcagt cagaaaaatg actacatcaa actcaaggcc attgctaaaa
    48901 atatcgctta tcgtgttcca tctgattatg gagaacttga aattaccatc aatctctcta
    48961 agcctgaaaa ggatccgaaa gagattgcgg cagccaagtt ggtgcaagct agtaattatc
    49021 ctcagtgtca actttgttta gagaatgagg gttaccatgg tcgggtcaac cacccagctc
    49081 gcaccaacca ccggattatc cgttttgaaa tggttggtca ggaatggggt ttccagtatt
    49141 cgccctatgc ttactttaat gagcattgta tctttttaga tggccagcat cgtcccatgg
    49201 ccattagtcg tcagagtttt gaacgtctgt tggctatcgt agagcagttt ccaggatatt
    49261 ttgctggatc taatgccgac ctgccgattg tggggggctc tattctaact catgatcatt
    49321 atcagggagg ccgtcacgta tttcctatgg aattggctcc cttgcaaaag accttccgat
    49381 ttgctggttt tgagcaggtc aaggctggaa ttatcaagtg gccaatgtct gtcctacgct
    49441 tgacttcgga ttccaaagag gatttgatta acttagctga taagattttc caggaatggc
    49501 gtcagtattc agattctagt gtgcagattt tggcagagac agacgggaca ccgcatcaca
    49561 ccatcacacc aatagcgcgt aagcgtgatg gacagtttga gttggacttg gtcttgcgag
    49621 acaatcagac ttcagcagag catcctgatg gcatctatca tccccacaag gatgtccaac
    49681 atatcaagaa ggaaaatatc ggcttgattg aggtcatggg cttggcaatc ttgccaccac
    49741 gtctgaaaga agaagtggag caagtcgcta gctatcttgt aggagaagct gttacagttg
    49801 ccgattatca tcaggagtgg gcagaccaac tcaaatccca acatccagac ctaacggata
    49861 aagaaaaagc ccttgcaatc gtcaaggact ctgtgggtgc tatctttgtg cgtgtacttg
    49921 aggatgcagg agtctacaag cagacagaac aagggcagac agcctttatg cgctttgtgg
    49981 aacatgtcgg aatttcacta gactaggagc tttctccttg cacagtccta taaaaagtag
    50041 tatcatagtg tcgtttgaaa tatcaggagg aaacgatgaa agattttcat tttgacgcta
    50101 tatctgcctt tgaaaattac gaaattgaaa aaatgagaga tggtcacgtt gtggtgacga
    50161 ccaaagtagt gaactcgtcg ctcaattact atggcaatgc ccatggtggc tatctattca
    50221 cgctatgtga ccaaatcagt ggtttggtgg ttatctcgct gggacttgat ggggtgacac
    50281 tccaatcctc tatcaactac cttaaggcag gaaaactcga cgatgtattg accattaaag
    50341 gagaatgtgt ccatcaaggc cgtacaacct gtgtgatgga tgtggatatc accaatcaag
    50401 agggcaaaaa tgtctgtaaa gcaaccttta ccatgtttgt cacaggccag cggtcagaag
    50461 acagacaggt aaggatataa agaaaggtga gtgggataaa tttatctcac tcatttttaa
    50521 tttatgagat atgttagaag gaaatataaa agagagtgat gaaatacaaa tgtaataggt
    50581 acatatatgt ggtatactag ttatagtaga ttttaattac ttatatcgag tgagttctca
    50641 tattagtgag gaatttttaa atggaattac actttaattt agaattagta gaaacctata
    50701 aaagtaatag ccaaaaggca cgtatcttaa cggaggattg ggtttatcgt cagtcttatt
    50761 gccctaattg tgggaacaat cccttaaatc attttgaaaa taatcggcct gtagcagatt
    50821 tttactgtaa tcattgtagt gaggagtttg aactaaagag caaaaaagga aatttttcat
    50881 caacaatcaa tgatggtgct tatgcaacga tgatgaagcg tgtgcaggca gataataatc
    50941 ctaatttctt ttttttaact tacacaaaaa attttgaggt aaataacttt cttgtccttc
    51001 cgaagcaatt tgttacaccg aaatcgatta ttcaaagaaa accacttgca ccaactgcta
    51061 gacgagcagg ttggattggt tgtaatattg atttatcaca agtaccttct aaaggaagga
    51121 tatttcttgt gcaagatgga caagttagag atccagaaaa agttacaaaa gaatttaagc
    51181 aaggtttatt tttaaggaag agctctctgt catcaagagg ttggacaata gaaattctaa
    51241 attgtataga taagatagag ggttcagaat ttacccttga agatatgtat cgttttgaaa
    51301 gtgacctaaa aaatatcttt gttaagaaca atcatatcaa agaaaagatt aggcaacagc
    51361 ttcaaatatt aagagacaaa gaaataatag aatttaaagg tagaggaaag tatcggaaat
    51421 tatgaaaacg aaacaacttg ttgcatcaga agaggtgtat gatttcttaa aagtcatctg
    51481 gcctgattat gaaactgaaa gccgttacga taacctaagt ttaatcgtct gtaccttatc
    51541 agatcccgat tgtgtgagat ggttatctga aaatatgaaa tttggtgacg aaaaacaact
    51601 agctttgatg aaggaaaaat atgggtggga agtaggagat aaattgccag agtggctaca
    51661 tagctcctat catagattat tgttaatagg tgaattattg gaaagcaatc taaaactgaa
    51721 aaagtataca gtagaaatta cagaaacttt atcacgttta gtaagtatag aggctgaaaa
    51781 tccagatgaa gccgaacgac ttgtaagaga aaagtataag agttgtgaaa ttgttcttga
    51841 tgcagatgat tttcaggact atgacactag catatatgaa taggtagatg tttttatttt
    51901 gtcacacaaa aaagaggctc gcacctcttt ttcttatttc tttttatgat ttaatacggc
    51961 attgaggaca atagcgagta ggctggctac gacgattccg tttgagaaga acatttggaa
    52021 ggctgtcggc atgctgacaa agagattact gttgttgaga ccgacacctg cagcgattga
    52081 aacagctgcg ataaggaagt tgtgttcatt gttagcaaag tcaactcggg cgaggatttg
    52141 catcccttga atagatacaa aaccaaacat caccagcatg gcaccgccga ggacggagct
    52201 tggaatgatt tgggcaaggg caccaaactt aggaagcagt ccaaggagaa ccaggaaacc
    52261 agctgcgtag tagattggca ggcgtttttt gatgcctgac aatttaacca aaccaacgtt
    52321 ttgtgaaaat ccggtgtaag ggaaggtgtt aaagattcct ccgagaagta cggccaaacc
    52381 ttctgcgcgg taaccgttgc gaaggcgcgt gctgtcgatt ggatcttttg tgatatcaga
    52441 caaggctaga taaacaccag ttgactcaac catagacacc gttgcgatga tacacatcat
    52501 gacaatagat gagatttcaa aggttggcat cccaaagtag agtggagttg ggacatggac
    52561 aagtggagct accgcaacag gagagaagtc caccaagccc atagtagcag caatggcagt
    52621 tccaacaacc agaccaatca aaatagagat agacttgata aatcctttgg taaagatgtt
    52681 gatcaagagg ataatcagaa cagtaatagc tgaaagcaag agactttgac cagttggctc
    52741 tggaacgtta tttcccatat ttccaatagc gacagggatc aaggttaaac caatcgtggt
    52801 aataacagat cctgttacga tagatgggaa gagattggct acttttgaga agatgcctga
    52861 aacaagaacc acgtaaatcc cagatgcgat aagggcacca aacatagcgc cactaccatg
    52921 gctttgccca atcataatca agggagcgac cgactggaat gcaactccaa gaacgactgg
    52981 gagtccaatc ccaaagtatt tgttgagttg gagttggagg aaggttgcca ccccacacat
    53041 gaagatatct gtagaaatca ggtaggtcaa ctgctcagct gaatagccaa gggctgtcgc
    53101 aatcatgatg ggaaccagga tagatcctga gtacatggct agtaagtgct gcaagcccag
    53161 aacggctgct tgcgagtgtt tttcttgagt ttgcattaga gatctgcctc cttaaatacg
    53221 acctgaccat tttcaaaacg atccaagcga gcaagtgata ggacagggta gcctgctttt
    53281 tcaagcaaat cacgaccatc ttggaaggat ttctcaatca cgataccgat agcttggact
    53341 gtggcaccgg cctgttcgat gatttgaatc aagcctttag cagcttggcc attagcaagg
    53401 aaatcgtcga taatcaaaac cttgtcctct ggtgagagga attttccagc gatagaaaca
    53461 gtgctggtca cctgcttggt aaaggagtag acttgagcag ttaagatgcc ttcgttcatg
    53521 gtgatgttct tagctttttt ggcgaaaatc atgggaacgt ttaaggcttc agctgtaaaa
    53581 acggctgggg caatacccga cgcttcaatg gttacgacct tggtaatgcc agtagcagca
    53641 aatttttccg caaaaacctt accaatctct cgcatcaagc taaagtcaac ttggtgggtt
    53701 aaaaaggaat ctaccttgag gatgttatca cccaagatat gcccatcctt gaggatgcgc
    53761 tcttctaata atttcataag acctcctaaa gtctaaaagt taatttactt gttgtttaaa
    53821 tatttctata gtgatccctt ttgctaatac tatatatttg ataaaactat tacgagcgaa
    53881 gcgagtctta tcaaatattt cccgttgtag tggtatcata gacaataatc ttgttattgt
    53941 ctatgacggg atttttgaga gtaaaatagt tcggggaact attttagcct aagcctagaa
    54001 atgaaagagc taggggctca aaaattaggg atgaaattcc ctggattcct gaaattattc
    54061 acaggataat ttcacctccc gtccgcacta attaagggaa atattaaaaa tattcaaaaa
    54121 agacctactt aatctctaag taagtcccct aaatagacat ggcaaaaacg gccatatctc
    54181 actgctgact tacttattgt taggtgttcc ggcaccttgt agaaacgtcg tgccaattca
    54241 cgacataaac aagtaaaacg atattcaatt ttaaataggc ttgagccaat gtttttattt
    54301 tacactaaat aactttagga atcaactatt ttgttagtgt tttggtttaa aaagcgaaca
    54361 aaaagaagag agggtgaaca aaaactccat tgtaagctaa catttatact aaatgaaaat
    54421 caaagagcaa actaggaagc tatccacaac ctcaaaacac tgttttgagg ttgtggatag
    54481 aattgacaga gtcagtatca tatacctacg gtaaggcgac gttgacgtgg cttgaagaga
    54541 ttttcgaaga gtattagaag atttttccat cataaaaggc atactatcaa gtttttagac
    54601 acctgacaat atgccttttt ctaactttaa agacttttcc caatttttat tattctactc
    54661 gctaaatctt aaaaaatagc catttggatc caaaactgca aattcatgag gatagatata
    54721 gggatcactg acacgaaact ttctcttggt caagggacga taaataggat agtttgcctt
    54781 catcactctt taatagagtt ttgaaacatc ctttatgcca aaggagagat tgactccacg
    54841 accaaatgga taggtcagtt cagctagttg atcctttgtt ccctcctcta acattagttg
    54901 acactcttca agagaaagag aaagttttct tctggacgtt ggtattcaat cctaaaaccc
    54961 agtaaaccac agtagaagga ccgggactgt tcgatattcg atacaagcaa ctcgggaatg
    55021 accgcattgt agtccatata gaaaatcctt acaagtcaat ttccaagaca atcggtgtat
    55081 ggtcttggcg agcacctgag tcaatcatat cagatttagt gaccttgtca gcgatacggt
    55141 tacttgtgag ccagtagtcg attctccagc ctgtattgtt gattttagaa gttttgctgc
    55201 gttgtgccca ccaagtgtag cgttcaggaa catcgccatg aacatggcgg aaggtatcag
    55261 taaatccagt tgccaatagg ttggtaaatc cagcacgttc ctcgtcagta aatccaggtg
    55321 aacggcggtt gctagcagga tttgcaaggt cgatttcatt gtgggctacg ttgtagtcac
    55381 cggtcgcaag gactggtttt tctttgtcta gttcagccaa atactccgca tatttgacat
    55441 cccagacttg gcgttcttcc aagcgtttga gaccgtcacc agcgtttgga gtgtaaactt
    55501 gggttacgaa aaatgcatca aattctagag tgatgatacg gccttccaag tccatggtag
    55561 aaggggcacc gatttctggg aagctgatcg taggcgtaag ttctttctta taaaggaaca
    55621 tggttccagc atagccttta cgggcaggct cttgggaaga gcgccacgtg ttttcgtagc
    55681 ctgggaagag ttcttctaaa atttccacgt gtttctttgt aggtcctttg gcagaaagct
    55741 tggtttcttg gatagcaata atatcagcat tttcagcgac caaggtttgt aggacttctt
    55801 gggacaattt ggcacgagct gagtcactag ttagggcagc gtttagggaa tcaatattcc
    55861 atgagataag tttcataaag ttaccttttt cattcagatt atagatttta ttataccaaa
    55921 aaaaggtcta tttccccaac gtatggtttg aaaaattact ctctttcgtt tataattaag
    55981 aatgatttta tgaaagggag tgaaaataca tgaaattcta ctcttatgac tatgtactca
    56041 gccaaatcgg tcagcaaaat ggtatcatgg ttggctttgg gattgttcta ttagctgtga
    56101 cagttttttt tgctttcaag gtatacaatg ataaaaaagg aaccgaattt cgtgagttgg
    56161 tcatgatttc agctctggcc ttatttagct ctgcttttgg tcagcatcac gacttatcaa
    56221 aacaatcaag tttctaacaa taaatttcaa actttacttc atttcatcga ggttgtttcc
    56281 aaagatttgg gagtagacaa gtcagaagtc tatgttaata cttccacaaa cacagatggc
    56341 gcacttatca aggtgggaga ttgctattat cgtgccctaa acggaagtga gccagacaag
    56401 tacctgttag agaaagtcga attgtataag acagacgcaa ttgaactggt ggatgtgaac
    56461 aaatgacact taattatatc gaaattttaa tcaaactggt cttgactctc aaatagctca
    56521 acaacaatgt tcactttgtg aaacgtttga ttgatggtaa gccaactctc cttatcaaaa
    56581 atgggaatat tgacccataa acctgtcgtt cagttggttt gtctgcatcg gatgtagccc
    56641 tcaaacttcg tagccaaggg attttccaga tgaagcaagt caaacgagct gtgcaagagc
    56701 aaaatgggca actcatcgtt gtgcaaatgg gagatgaaaa tcctaagtat ccagttgtga
    56761 ctgacggtgt gattcaagta gatgtcttgg aatcgattgg tcgtagcgaa gagtggttgc
    56821 ttgataacct cagtaaacaa gggcatgaca atgtagccaa tatctttatt gctgaatatg
    56881 acaagggtgc tgttacagtc gtaacttatg aataagaaaa acctggggtc ttgtactctt
    56941 cgaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta tgtaggttac tgacttcgtc
    57001 agttctatct acaacctcaa agcagtgctt tgagcagcct gcggctagtt tcctagtttg
    57061 ctctttgatt ttcattgagt attggcctca ggtttccatt tgcaatcaga aagggatttt
    57121 atgtccatta ttcaaaaact ttggtggttt ttcaagttag aaaaacgccg ttatctagtc
    57181 gggattgtgg ccctggtctt ggtttccgtt ctcaatctca ttcctcctat ggttatgggg
    57241 cgggttattg atgccatcac atcggggcaa ttaacccagc aggacctcct tcttagccta
    57301 ttttacttgc tacttgcagc ctttggtatg tactatttgc gctatgtgtg gcgtatgtat
    57361 atccttggga cctcttattg cttgggacag atcatgcggt ctcgcttgtt taagcatttc
    57421 acaaaaatgt cgtcagcctt ttatcaaacc tatcggacgg gtgatctgat ggcacacgca
    57481 accaatgata tcaatgcctt gactcgttta gcaggtggcg gtgtcatgtc tgcggtggat
    57541 gcctctatca cggctctggt gactttgttg accatgctct ttagcatctc atggcagatg
    57601 actcttgttg ccattctccc cctacctttc atggcctata cgactagtcg cctagggaga
    57661 aagactcata aggcctttgg cgaatcccaa gctgcttttt ctgaactcaa taacaaggta
    57721 caggagtccg tatcaggtat caaagtgacc aagtctttcg gttatcaggc agacgagttg
    57781 aagtcttttc aggcagtcaa tgaattaacc ttccaaaaga acctgcaaac catgaaatat
    57841 gatagtctct ttgaccctat ggttctcttg tttgttggtt cgtcctatgt tttaacgctt
    57901 ttggttggct ccttgatggt tcaggaaggg cagattacag ttgggaatct agtcaccttt
    57961 atcagctatt tggatatgct ggtctggcct cttctggcca tcggtttcct ctttaatact
    58021 actcagcgag ggaaggtttc ttaccagcgg attgaaaatc ttttgtctca ggaatctcct
    58081 gtacaagacc ctgagcttcc tctggatggt attgaaaatg ggcgtttgga gtatgccatt
    58141 gacagctttg cttttgaaaa tgaggaaaca ctgacggata ttcactttag tttggcaaaa
    58201 gggcaaacac tgggcttggt tgggcagaca ggctctggga aaacgtcctt aatcaagctc
    58261 ctcttgcgtg aatacgatgt ggataagggt actatttatc taaacggtca cgatattcgg
    58321 gactatcgtc tgacagacct tcgcagtctc atgggctatg ttcctcagga ccagtttctc
    58381 tttgcgactt caatcctaga caatatccgc tttggcaatc ctaacttgtc cctttcagcg
    58441 gtcgtggaag ctactaagct agcccgagtt taccaagata ttgtagacat gcctcaagga
    58501 tttgatacgc tgattggtga aaaaggagtc agtctttctg gtggtcaaaa gcaacggttg
    58561 gctatgagtc gggctatgat tttagaccct gatatcttga ttttggatga ttccttatcc
    58621 gccgtagatg ccaagacaga gtatgcgatt atcgacaacc tcaaggagac gcgaaaggac
    58681 aagacaacca ttatcactgc ccatcgcctg agtgcagttg tccatgcaga tttgatttta
    58741 gtcctgcaaa atggtcaaat tatcgaacga ggcaggcacg aagacttgct agctttggat
    58801 ggctggtatg cccaaaccta ccagtctcag cagctggaaa tgaagggaga agaagatgca
    58861 gaataaacaa gaacaatgga ctgtattgaa gcgcttgatg tcctatctca agccttatag
    58921 actcctgacc tttttggcac tcagttttct cctagcgacg acggtcatta aaagtgtcat
    58981 acccctcgtg gcttcccact ttatcgacca gtatctcagc aatcttaacc aactagccgt
    59041 taccgttttg ctggtctact atggtctcta catcctacaa actgtagttc agtatgtagg
    59101 caatcttctc tttgcgcgcg tgtcttacag tattgttagg gatattcgtc gggatgcctt
    59161 tgccaatatg gagaaactgg gcatgtctta ctttgacaag acgccagcag gttctatcgt
    59221 ttctcgtttg accaacgata ccgagacgat tagtgatatg ttttctggga ttttatccag
    59281 ctttatctca gcagttttta tctttctgac aaccctttat accatgttgg tgctggattt
    59341 tcgtttgaca gcattagtct tgctctttct ccccttgatt ttccttttgg tcaatctcta
    59401 tcgaaaaaag tcagtgaaaa tcatcgagaa aaccagaagt ctcttgtcag atatcaatag
    59461 taagctggca gagaatatcg agggaatcag gattattcag gcttttaatc aagagaagcg
    59521 cctgcaggca gaatttgatg aaatcaacca agagcacttg gcctatgcca accgttctgt
    59581 agccttggat gccctctttt tgagacctgc catgagtttg ttgaaacttc taggttatgc
    59641 tgtcttgatg acctattttg gctatcgtgg tctttctatc gggataacgg ccgggaccat
    59701 gtatgctttt atccagtaca tcaaccgcct ctttgaccct ttgattgagg tgacgcaaaa
    59761 cttttcaaca ctgcaaacgt ctatggtttc tgcaggccgt gtctttgcct taatcgatga
    59821 gaggacctat gagccccttc gagaaaatgg gcaagccaaa gtcaaagaag gcaatatccg
    59881 ttttgaacat gtgtgtttct cgtatgacgg taaacatccg attctggatg acatttcttt
    59941 ctctgttaat aagggtgaaa ccattgcctt tgtaggtcat acaggttcag ggaaatcgtc
    60001 tattatcaat gtcctcatgc gcttttatga attccagtca gggagagttc tcttggatga
    60061 tgtggatatc agggatttca gtcaagaaga gctgagaaaa aacatcggtt tggttttaca
    60121 ggaacccttc ctctattatg gaactattaa gtccaatatc gccatgtacc aagaaatcag
    60181 tgatgagcag gttcaggctg cggcagcctt tgtggatgca gattccttta ttcaagaact
    60241 tcctcagggg tacgactccc ctgtttccga gcgtggttcg agcttctcta ctgggcagcg
    60301 ccagcttctt gcctttgcta gaacagtcgc cagccagcct aaaatcctga ttttggatga
    60361 agcgacagcc aatattgact ctgaaacaga aagtttggtt caagcttctc tggcgaagat
    60421 gagacagggc cgaacaacta ttgctatcgc tcaccgcctt tctactattc aagacgccaa
    60481 ctgcatctat gtcttggata agggacgcat tatcgagagt ggaacccatg aggaactctt
    60541 gactctggga ggaacctatc acaagatgta tagtttgcag gcaggggcca tggcctatac
    60601 tctttgaaaa tctctttaaa ccatgtcagc tttatctgca atctcaaagc tgtactttga
    60661 ttttcattga gtactagaag gaaatccttc aaattacaga tttctttcac cgccttttcc
    60721 attttgtggt ataatgaaaa atgttgacaa atagtataat aaaaacaaag gagaacagca
    60781 tgctgaaatg ggaagacttg cctgtggaaa tgaaatcaag cgaggttgag tcttactacc
    60841 agcttgtctc taaaaggaag ggttcgctga ttttcaagcg ttgcttggac tgggttttgg
    60901 ccttggtctt actggttcta acttctccca tctttctcat cttgagcatt tggatcaagt
    60961 tggatagcaa ggggccagtg atttacaagc aagagcgtgt gacccagtac aaccgtcggt
    61021 tcaagatttg gaagttccgt accatggtga cggatgcgga taaaaaagga agtctggtga
    61081 cttctgctaa cgatagccgt attaccaagg ttggaaattt catccgacgt gtccgtttgg
    61141 acgaactgcc tcagttggtc aatgtcctta aaggtgagat gtcctttgtc ggtacacgac
    61201 ctgaagtgcc acgttataca gagcagtata gccctgaaat gatggcaacc ttgctcttgc
    61261 aagcaggaat tacctctcca gccagcatca actacaagga tgaggacacc atcatcagtc
    61321 aaatgacgga gaaaggtctg tcagttgatc aggcctatgt ggagcatgtt cttcctgaaa
    61381 agatgcgcta taacctcgcc tatctccgag agtttagttt ctttggggac atcaaaatca
    61441 tgtttcaaac cgtgtttgag gtactaaaat aaagtagtca taagaaaatg agtacagata
    61501 aaaggagcaa atcaatgcca aattacaata ttccattttc accgcctgat atcacagaag
    61561 cagaaattgc tgaagtagcg gataccctgc gttctggttg gatcacaaca ggtcctaaaa
    61621 caaaagaact ggagcgccgc ttgtctcttt acacacagac acctaagact gtttgtctca
    61681 actctgcgac agccgctctg gagttgattt tacgcgtttt ggaagtggga cctggtgatg
    61741 aagtcatcgt tccagccatg acctatacgg cttcatgtag tgtcattacg cacgtgggag
    61801 caacccctgt catggtggat atccaagcag atacgtttga gatggactat gacctgcttg
    61861 agcaagctat cactgagaaa actaaggtga ttatcccagt agagctcgca gggattgttt
    61921 gcgattatga ccgtttgttc caagtcgtgg agaaaaaacg tgacttcttt accgcttcaa
    61981 gcaagtggca aaaggccttt aaccgtattg tcattgtctc tgatagtgcc cacgctttgg
    62041 gatctactta taaaggacaa ccttctggtt ctatcgctga ctttacttcc ttctcattcc
    62101 atgccgttaa gaactttaca acggcagaag gtggaagtgc gacttggaaa gccaatccag
    62161 tgattgatga cgaagagatg tacaaggaat tccaaatcct ttcccttcac gggcaaacta
    62221 aggatgctct tgccaagatg caattggggt catgggaata cgatatcgtt acaccagcct
    62281 ataagtgcaa catgaccgat atcatggctt cacttggttt ggtacaattg gaccgctatc
    62341 caagtttgtt gcaacgccgt aaggacattg tggaccgcta tgatagtggt tttgcaggtt
    62401 ctcgcatcca tcctttggca cacaagactg aaactgtcga atcttcacgc cacctctaca
    62461 tcacccgtgt agaaggagca agcctagaag aacgcaacct catcatccaa gaattggcta
    62521 aagcaggaat tgcaagtaat gttcactaca aaccgcttcc tctcttgaca gcctataaga
    62581 atcttggatt tgatatgacg aactatccta aggcctatgc cttctttgag aatgaaatca
    62641 ccctccctct tcatactaaa ttaagcgatg aagaagtaga ctatatcatt gagactttca
    62701 aaacagtttc tgaaaaagtg ctaactttat caaaaaaatg acaaactaca gtcaagcgaa
    62761 agtgatcctg tccctaaaaa gtctaattga gtgtaaaaac tgttgttttc aattgataat
    62821 agtttacacc tgtagttgag gcctctttct cctcagagag agaattttta taggattttc
    62881 ctttcttgtg ggagtcccgt ggtttgaaat aagatgtgag caatttggta tagcatttag
    62941 aatccttact agacatcatt tagaaaatct agtgtcttgt tctagttttc aattcaccct
    63001 attttttgaa agacgtgagt ttccatgagt gagattgtgg aaactcgcgt cttttttttg
    63061 ttttcagaat attgttcaaa gttttgtgcc tgtctttcat gttctagtca ttcttttgca
    63121 tgatagaatt tatagcatgt tgatattata ataatacgaa tatcccatat gtttagtgat
    63181 gcttgctata catcattaga tctcccgcga gacaatctat aaaacacttg tctacgatta
    63241 cctatatgcc ctattccagt attttagaag cactgcatct atttttatcg aggttaaatc
    63301 tagcttttat agaaggtcta tttaagaaat atattgtagt gttttagttt caatccgcca
    63361 tatgagcgat attcaggtaa atatccccgg cgaatgcttg tatgacaagg tatttgttct
    63421 ttcatttata atttacaaca tatcaataaa tttaaatata gtaaatggga tattttatat
    63481 tcaagctaag aaagatagca tcacttttga atggaaggct aaagagcaaa ctaggaagtt
    63541 ggccatagat agctcaaaac cctgctttga ggttgtagat atagtaaaat gaaataagaa
    63601 taggacaaat tgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
    63661 tactatttta gtttcagtct actatagaac tgaccaagtc agtaacctag acttagggca
    63721 aggcagcact gacctagttt gaagagattt ccgaagagta taaattttaa tattttcttg
    63781 tgttattcct tgacaattca atttggaaaa tatatgataa agataatgac agcggtgtca
    63841 ttctatctat tttaagaaaa gtaataatca attgttaaaa atagtaaaaa aattggaggt
    63901 tctgatgaaa tattttgttc ctaatgaggt attcagtatt cgtaaattaa aggtggggac
    63961 ttgctcggta ctattggcaa tttcaatttt gggaagccaa ggtattttat cggatgaagt
    64021 tgttactagt tcttcaccga tggctacaaa agagtcttct aatgcaatta ctaatgattt
    64081 agataattca ccaactgtta atcagaatcg ttctgctgaa atgattgcct ctaattcaac
    64141 cactaatggt ttagataatt cgttaagtgt taatagtatc agctctaatg gtactattcg
    64201 ttccaattca caattagaca acagaacagt tgaatctaca gtaacatcta ctaatgaaaa
    64261 taagagttat aaggaagatg ttataagtga cagaattatc aaaaaagaat ttgaagatac
    64321 tgctttaagt gtaaaagatt atggtgcagt aggtgatggg attcatgatg atcgacaagc
    64381 aattcaagat gcaatagatg ctgcagctca agggctaggt ggaggaaatg tatattttcc
    64441 tgaaggaact tatttagtaa aagaaattgt ttttttaaaa agtcatacac acttagaatt
    64501 gaatgagaaa gctacaattc taaatggtat aaatattaag aatcaccctt ccattgtttt
    64561 tatgacaggt ttatttacgg atgatggtgc gcaagtagaa tggggcccaa tagaagatat
    64621 tagttattct ggtggtacga ttgatatgaa cggtgctttg aatgaagaag gaactaaagc
    64681 aaaaaatcta ccacttataa attcttcagg tgcatttgct attgggaatt caaataacgt
    64741 aactataaaa aatgtaacat tcaaggatag ttatcaaggg catgctattc aaattgcagg
    64801 ttcgaaaaat gtattagttg ataattctcg ttttcttggg caagccttac ccaaaacgat
    64861 gaaggatggg caaatcataa gtaaggagag cattcagatt gaaccattaa ctagaaaagg
    64921 ttttccttat gccttgaatg atgatgggaa aaaatctgaa aatgtgacta ttcaaaattc
    64981 ctattttggc aaaagtgata aatctgggga attagtaaca gcaattggca cacactatca
    65041 aacattgtcg acacagaacc cctctaatat taaaatttta aataatcatt ttgataacat
    65101 gatgtatgca ggtgtacgtt ttacaggatt cactgatgta ttaatcaaag gaaatcgctt
    65161 tgataagaaa gttaaaggag agagtgtaca ttatcgagaa agcggagcag ctttagtaaa
    65221 tgcttatagc tataaaaaca ctaaagacct attagattta aataaacagg tggttatcgc
    65281 cgaaaatata tttaatattg ccgatcctaa aacaaaagcg atacgagttg caaaagatag
    65341 tgcagaatat ttaggaaaag tatcagatat tactgtaaca aaaaatgtaa ttaataataa
    65401 ttctaaggaa acagaacaac caaatattga attattacga gttagtgata atttagtagt
    65461 ctcagagaat agtatattcg ggggtaaaga aggaattgtt attgaggatt caaagggtaa
    65521 aataaccgtt ttaaataacc aattttataa tttatccggt aagtatatat cattcatcaa
    65581 atctaatgca aatgggaaag aacctgttat acgtgatagc gatggtaatt tcaatattgt
    65641 aacggagaat gggctttaca aaattgtaac aaataattta agtgataaaa acgaaaaaga
    65701 aaaaaacaaa gaggaaaaac aatctaattc aaataatgta attgatagta accagaagaa
    65761 cggagagttt aactcaagta aagataatag acaaatgaat gacaagatcg acaataaaca
    65821 agataataag acagaagaag taaactataa aatagttgga gatggcagag aaactgaaaa
    65881 tcatattaac aaatctaaag aaatagtaga tgtaaaacaa aaattaccaa agactggttc
    65941 gaacaagatt atggaactat tcttaacagt gacaggaatt ggtttacttt tgacactaaa
    66001 agggttgaag tattatggta aagataaata aaatttgttc gatacaagga agttccgtag
    66061 aaaatgagga tattgtaggt tcacaaaatc agtatttttg gattattggt ggagctacag
    66121 atttatataa ttctaaagag gagataggtt attcagtctc agaagttgta catattttat
    66181 cagaaagttt gtcggttaat tgtaaagaat caaaaactct taaacaaata tttgaaactg
    66241 ctttactcga ggttaaagat gaaatcggtt taaactcata taaattaaca gagtatagta
    66301 aaatgaaata ataataggac aaatcaatca ggacagtcaa atcgatttct aacaatgttt
    66361 tagaagtaga ggtgtactat tctagtttca atatactata ttatcgctta ccaatatttg
    66421 ctaaactttc agaaaaaaag ttggagtata tgatgctagg tgactgcgtc atgttagtaa
    66481 acgaaatgga aataactgat catagagtag ataacttatt tgaaaaaggg aaaaatgaga
    66541 taaaagattc aattggtaca aatagtgttt taaataaaaa aattatttta caaaaaatca
    66601 gaaaattatc taatcaaccg agtgggtact ggataggttc gttggatgag agatttttag
    66661 accatgctat tattaatcaa atagatgtta ctagtgaaca aattgtttta atgagcgatg
    66721 gcttttatga attctatcaa aataatcaaa ataaaacttt tgaagagtta attaagatga
    66781 gatttaattc ttctgctatt gatccaatct atggaaagaa ggatgatgca agtattctag
    66841 tcattgatgt ttgatatatt gtttaaaata ttaattgtta ctattgaact ttgttaagaa
    66901 gaggtaccta aatgttaagg ttatatttag aaaatgaaat tatagaatta tcaaataatt
    66961 tagagaccat ttgggtatct gtgcttgata aatatgagaa gttatttgaa tatttatcaa
    67021 atgaagaacg agtagaattg attaaagaag atttaatcat aaatgagtca gttctaaata
    67081 ttgataaaaa aggatatgag ttaatttgtt tacaacatcc tgtttcatat gacttaagaa
    67141 gaattattag tgtaataaaa atatcaactg acattgaacg tattggggat agaattgttg
    67201 aaattttaaa aaatctacag attcttcaaa ataatgaaat tttgaagaaa attatttcaa
    67261 aaataaaaat acttcatgaa gttatcggac tgcatatgaa tagggctata tcttgttata
    67321 gagaggaaca atctggatgt ttagatatgg ttgttataca aaaacagaat gagatagaag
    67381 agcttagtat aaatatggaa aagaaaataa tgaattacat atttgaagat gatgggaacg
    67441 tttctgaagt aattagtgct ttagatatta ttcatcacct tgataaaatt gctcatacta
    67501 cgcaagcaat ttataaatgg ataatgtata gaaaatatgg gaacataaat tagaaagaaa
    67561 aatatatgaa aacaattatt gataattttg ttgatagagt aattgaatac ggaatgtata
    67621 atgaaattga caaaatatat gtgaaaaata gagtactagc gttaataggt gaggagggaa
    67681 ttgatcgcat ttccgatgaa aatgacctga aacaaataaa agattactta gtggaaatcg
    67741 ccttaaaaaa cggtaaaatt aaagatttaa tcgaggaaaa ggaatgttta ggagcagagt
    67801 taatgaattt catagttcct ttacctagtc gattaaatga tattttttgg agttcatatg
    67861 atatatcacc tcaagaagca gttgaagagt tttataagtt aagtaaagat agtgattata
    67921 ttaaaacttc tgctattgct aagaatattg agtttcgagc atcaactaaa tacggagagc
    67981 tagagattac gataaatttg tcaaaacccg aaaaagatcc aaaaacaatt gctgctgaaa
    68041 aattagtaaa agcaactaat tatcccaaat gtttactatg tatggaaaat gaaggatatc
    68101 aggggcgaat aaattatcca gcacgttcga atcatagaat tattcggttg aaacttggtg
    68161 acgaagtatg gggattccag tattctccct actcatactt taatgagcat gcgatatttt
    68221 tgaatagtca acatgtacca atggctatta cctctaaaac atttgaacaa ttattggaga
    68281 ttgttgatat tttgccagga tattttgctg gttcaaattc tgatcttcct atctcaggag
    68341 gctccattct tagtcataac cactaccagg gagggaaaca tattttccca atggaaaaag
    68401 caaaatttga gagtgaattt tgttttaaag actttgagga tgttaatgct ggtattgtaa
    68461 aatggccaat gtcagtaatt aggttacaaa gtgaaaataa aaatcgcttg ttagatttag
    68521 ctactaaaat tctaaataag tggagagaat attcagattt agaagtagac atcattgcta
    68581 tgactgaaga tgtcccacac catacggtga ctcctattgc tcgtaaagtg gacgggagat
    68641 acgaattaga tattgttcta agagataatc atactactga acaataccca gatggtgttt
    68701 tccatcctaa tcaagatgta caacatatta aaaaggaaaa tatcgggtta atcgaagtga
    68761 tgggacttgc gatattacca cctcgtttga aaccagagtt agaagaagtt ggaaaatatc
    68821 ttttaggaga ggataatgca attgcggatt atcatttaga atgggccgac caattgaaag
    68881 aaaaatatcc tcgcattaat aaagaagagg ttaatagcgt agttcaacac gaagcaggac
    68941 aagtgtttgc gagagttctg gaagatgcag gagtttataa gaatacaccg tctgggcatg
    69001 aagcgtttat gagatttgtt aagtcggttg gaattaatta ggaggaaacc cagatggcaa
    69061 tattggtaac aggcggagct ggttatattg gtagccatac cgtagtagaa ttactaaatt
    69121 taggaaagga agttatcatt gtcgacaacc tttcgaactc tagcaaattg gtgctagacc
    69181 gtattgaagc aattacagga atacgtcccg tgttttacga attagatgtt tgtgataaac
    69241 aagcattgag aaaggtattt gaacaagaat cgattgatgc tgcaattcat tttgcaggtt
    69301 ataaagctgt cggagaatcc gtgcaaaagc ctgtgatgta ctacaaaaat aatattatga
    69361 gtacattggc acttgttgaa gtgatgtcag aatttaatgt taaaaagatt gtcttttctt
    69421 caagtgcgac tgtatatgga attaacaatc agtcacctct aattgagacg atgcaaacaa
    69481 gtgcgacaaa tccttatggg tatacgaaag tgatgcttga gcaaatttta aaagatgttc
    69541 atgtggcaga ttcagaatgg agtattgcgt tgcttcgtta tttcaatcca attggtgctc
    69601 atgagtctgg tttgattggg gaagatccct caggaattcc taacaacttg atgccttata
    69661 ttgcacaagt agcggtaggt aagctatcag agctaagtgt gttcggaaat gattatgata
    69721 cgcttgatgg tactggtgtg cgtgattata tccatgtagt agatttagca ataggacata
    69781 taaaagcttt agaaaaagta tctgaaaaaa cagatgttta tatctataac ctaggctcgg
    69841 gagaaggcac tagtgtatta caacttgtaa atacatttga aagtgttaat aagatcccta
    69901 ttccttataa aatagttcca agacgttcag gagacgttgc aacttgttat gcaaatgcag
    69961 acaaagcata taaggaatta aattggagga caacaaaatc gattgaagac atgtgtagag
    70021 atacatggaa ttggcaatca aaaaatccca atggctataa ttgatgatac tgtctatatg
    70081 agtgctgtat tttgaaaaaa ttacttaacc ttttaatgaa atgcatattt aatgaaagat
    70141 aaatttaaaa aaatgtttgc aagtgcttga caaaggaaac ggtttcattg tataatgtaa
    70201 acatggtgac accgatgtca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa
    70261 aattaagttc aaagagaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa
    70321 tctttatact aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga
    70381 attaccattt atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat
    70441 tgaattgttg tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga
    70501 tacaccttta caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt
    70561 ggatgaagaa attcatatgc gtataactga aatgggaaaa caaaacatac tagttgaacc
    70621 tgcagatgaa gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc
    70681 aggtgtttgt ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg
    70741 gattcctcta accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga
    70801 aattttatta gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga
    70861 agatatgaga caatttgttc catatcacga aaaatttaaa taaaataata aaaaaggaga
    70921 acttatcatg aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac
    70981 tacacttgct gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa
    71041 agctgataaa agtcaagaat tagttatcta ttcgaactca gtctcaaatg gtcgtggtga
    71101 ttggttaact gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatcgctgg
    71161 cgctcaatta gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt
    71221 tggaattggt gctgttgact caaataaaat tagagatcaa aaattactag tacagtacaa
    71281 gcctaaatgg ttagataaaa ttgatcaatc tttatcagat aaagataatt attataatcc
    71341 tgtgattgtt caaccattag ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga
    71401 ttggactgaa ttaggtagta agtataaagg taaatattca atttatggtc ttcaaggtgg
    71461 tacaggacgg gcaattctag caagtatctt agttcgttac cttgatgaaa aaggagattt
    71521 aggcgtatca gaaaaaggat gggaagttgc aaaagaatac tttgcaaatg cctatactct
    71581 tcaaaaaggt gaaagctcag ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg
    71641 tatgatctgg ggttctggag cgttaattgg acaaaaagaa caaaatgttg aattcaaagt
    71701 tatgactcct gagattggtg taccatttgt aactgaacaa actatggttt taagcactag
    71761 taaaaaacaa gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt
    71821 agaatatagt aaaaaatttg gatctattcc tgcaaataaa gatgccctaa aagagttacc
    71881 tgaagatacg aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt
    71941 tggaaagcat ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat
    72001 aagagttatt ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag
    72061 agaggctttt ggtttagtaa tagagggagt tagtgagatg attaaatttg ataatattca
    72121 aattaaatat ggtgattttg ttgcaattga taatctgaat ttagatatac atgaagggga
    72181 attctttaca tttcttgggc cttcaggatg tggtaaatca actactttga gagcattagt
    72241 aggtttttta gatccatcat caggaagtat tgaagttaat ggaacagatg tcactcattt
    72301 ggaacctgaa aagcgtggaa ttggtattgt atttcaatct tatgcgctat ttccaactat
    72361 gactgttttt gataatattg catttggttt aaaagttaag aaggtagctc cagatgttat
    72421 taaagctaaa gtatcagcag tggcagcaaa aattaagatc tctgatcaac agttacagcg
    72481 taatgtatca gaattatctg ggggtcaaca acaaagggta gcattggctc gtgctctggt
    72541 tcttgaacct aaaattcttt gtctagatga accattgtca aaccttgacg caaaattacg
    72601 tgtagatttg agaaaagagt tgaaaagact tcaaaaagag ttaggtatta ctactttata
    72661 tgttactcat gatcaagagg aagccttgac tttatctgat agaattgcag tctttaacaa
    72721 tggatacatc gaacaggtcg gtacaccagt agagatttat cataattctc aaactgaatt
    72781 tgtatgtgat ttcattggag atattaatgt tttgaccgat gaaacagtcc acgaagtatt
    72841 actgaaaaat acaagcgttt tcttagaaga taaaaaaggt tacattcgat tagagaaagt
    72901 tcgattcaat cgtgaaacta aacaagattt tattctaaaa gggacaatta ttgatgttga
    72961 gttttctgga gttacaattc actatacaat aaaagtttct gaaagtcaga ttcttaatgt
    73021 aacaagtatt gatagtcagg ctgctattag atctgtcgga gaaagtgtgg aattatttat
    73081 cacaccatca gacgttctgc aattttaagg aggtgcagta tgcgtcataa attaaattta
    73141 aaagattggc ttattcgttt agggttaatc tggttcttag taacatttat tatttatcca
    73201 aactttgatc tagtagtgaa tgtatttgta aaaggaggag aattttccct tgatgctgta
    73261 catcgtgttc taaaatctca gagggcactt cagagtatta tgaacagttt taagttagca
    73321 ttttcactca ttattacagt taatgtcgta ggtattcttt gtgttctatt tacagagtac
    73381 tttgatatta aaggtgctaa aattttaaaa ttaggttata tgacctcttt aatttatgga
    73441 ggagtggttt tagcgactgg atataaattt gtctatggtc cttatggatt gattacaaaa
    73501 tttttacaaa atgttatccc ttctttagac tctaactggt ttattgggta tggtgcagtc
    73561 ttattcatta tgacattttc aggaactgct aatcatacat tgtttttaac aaatacaatt
    73621 cgaagcgttg actatcacac tattgaggct gctcgaaata tgggagcaaa accatttact
    73681 gttttccgaa aagtagtgtt accaacctta attccaactc tatttgcact tactattatg
    73741 gtttttctta gtggtttatc tgcagtagca gcacccatga ttgttggtgg taaagaattt
    73801 caaactataa atccaatgat tattacattt gcagggatgg ggaattctca tgatttagct
    73861 gccttacttg caattatttt aggtattgca actacaattt tgcttactat catgaataag
    73921 atagaaaaag gtggaaatta tatttctatc tctaagacta aagcgcctct taaaaaacaa
    73981 aaaattgcgt ctaagccttg gaatatcatt gctcacattg tagcatatgg attgttcaca
    74041 gttttcatgc ttccactaat ttttatagta ttatactcat ttacagatcc agttgcaatt
    74101 caaacaggta acttaacatt atcaaacttt actttagaaa attatcgctt attctttagt
    74161 aatagtgcgg cattctctcc attcttggtc agctttattt attctattat tgctgcgaca
    74221 acagcaacaa ttctcgcagt tgtatttgct cgtgttgtca gaaaacataa atctcgtttt
    74281 gatttcttat ttgaatatgg tgctctactt ccttggttac taccaagtac acttttagca
    74341 gtaagtttat tatttacttt taatcagcca caatttcttg tcttgaatca gattttggta
    74401 ggtagtttgg taattctact tattgcatat atagttgtaa aaatcccatt ttcttataga
    74461 atggtacgtg ctattttatt tagtgttgat gatgagatgg aagatgcagc aagaagtatg
    74521 ggtgcttcac ctttttatac tatgatgaag gttatcattc catttatttt accggttgtt
    74581 ctctctgtta ttgctttaaa ctttaactct ttattaactg acttcgactt atctgtattc
    74641 ctttaccatc ccctagctca accattaggt attacgattc gatctgcagg tgatgaaaca
    74701 gcaacatcta atgcacaagc tctggtattt gtttatacaa ttgttctgat gattatttct
    74761 ggaacggtat tatacttcac acaaagaccg gggcgtaaag taaggaaata atcatgacag
    74821 ccactagtct tgggttatca aatattgaaa tagttgtcag gattgtttta tcagtagtca
    74881 ttggtagtat aattggttta gagagaggga gcaaatccca gcctgcaggc atccgaactt
    74941 atagtattgt ttgtctagct gcatgtttga ttatgatgac gaatgaatac gtatcttata
    75001 aatttgggac aggagatcct acacgattag gagctcaagt tatatcaggt gtgggttttc
    75061 taggcgctgg aacgattctt attacagata aaaagaaaat tacaggtctg acaactgcag
    75121 caggcatttg ggcttcggca ggaattggat tagctattgg agtaggtttt tatgagggag
    75181 ctcttttagt agccatttct gtttggggtg tgatatccat gttccaacca ctaaaaaaat
    75241 atctgcaaaa tcgttctaaa atgattgaat tgtatatagt agttaaatct acagaagcct
    75301 ataatcgtgt attggtttat tgtgcagaaa atggtatcag aatgaccgat tcaagaacag
    75361 cgtttggaga tgttaattct gacagaattg aatactttga tgttccggac aaaaaaatag
    75421 cgtcatttat tactctggaa ttatcaggta gatttgaaca tcttcgactg atggaagaaa
    75481 ttgctaatat tgtaggtgtt atttatgtcg aagaaattag ctgaaattta gtaaacaaag
    75541 ggacagatgt ttttgtcctt ttgtttttta gatgttttaa tcatctaatt tttgagtaga
    75601 tttttgctca gaggttttta tgaaagatta taaaatcaat tttgatttag gtaaaataga
    75661 atatttgata ataattgttt gatacaagta tacaaattta tttcttttta tgatatttgt
    75721 gaaatggtgt ttgcctttca tttacctcct gatgagttga taacaaatgt tatctttaaa
    75781 gaaaaaatta actctatgtt aaaatgttac attgacaggc tattatatgt ttttataaat
    75841 cctacacatt ttactgaaaa agttaatcta caattttatg gcagtttttt ctcatatgaa
    75901 tttatttgtc gtgaagttgg aaacattctt aaaaataaag gtgtgaaatg caatttaaac
    75961 ttttttgaag ggaaagaata tttgtaaaat taattttgtg aatttgtgga tcttaaataa
    76021 tttactaaat tctcttgtta aaaaaaatta aatattgtat agtaatatta gaatgttcgt
    76081 aatggaggac tgaaatgaaa aatataaatg ggaaaaaggt aactatttat gatattgcac
    76141 gtttatcagg tttttctcca aaaacagttt cacgagttat taatggtgga gtaaatgtta
    76201 aagaagaaac ttatcaagcg attcaaaaag ttatagagga attgtcgtat attccaaatg
    76261 cgtatgcaaa aaatttaact aaaaaagaag ctataaatat attgatttct gtaaaaaaaa
    76321 tcgactcttt tcctttaatt tggtttcata cgctgttaga taaagtgtta cggacgtgta
    76381 aagaatttgg tgttaatgct atagttgagt actttggaga ggaggataca attagtaatt
    76441 caattatatc aagcacaggt agcctagtag atggtgttat tgttttttat gaaagtgtag
    76501 atgatatcag aattcagtat ttaaagaaga accatatgcc ttttcttgtt ttcggtgaat
    76561 ctcaaacgtc tggagtagtc tatgtatcta ataataattt tcaagctact tatgatatga
    76621 tgaaagctgt aactgaagaa aaatttaaaa atatgtggtt gcttatggga ggagaatccc
    76681 atgttaataa ggatcgtgaa agaggtgtgc gttcttttct gaatgataaa aattacttta
    76741 tggatttaaa agtcatttat ggcttatcta caattgattc agtttattct tatgcaatgc
    76801 agcacttgac tacccaaaat tatccggaca ttatttttgt ttcaggagat gaaaaggttc
    76861 agggcttgat tcgtgcgtgc tatgagaaag gaattcttat tccagatgat atttctatca
    76921 ttggatttga taatattcct atttctcagt attatactcc agctttgtct acaattgctc
    76981 ccaattatgt taaattggct aaagaaatga tagaaggtgt tttagcaatt attaaagggg
    77041 aaagtgtcac atctgttgaa gtttctccta aatttgttag gagacagagt ttctagtatt
    77101 gtttaattct tgaaaatcct agtggaaaag atggagtgtt ctaaaataag ttctgtttag
    77161 cctccattca gtttctattg agttggatcc aatttctaac aagtgggaca tgttcatgtt
    77221 cgatctaagg aagacatggt catattcgaa tgatattttc aaaaaaatcg taaaaaagtc
    77281 ttgacaaaga aaaaacaaag tattaaaata agttcaacaa atcagaaaag taactatttt
    77341 tgatcttcag ggagcctgtg gtgattgtga ataggtggtt ggaagtagtg aaagtgggct
    77401 gattttgaaa atgaatttga aacaatgaaa attcggtgcg cacaccttac agtgcagctt
    77461 gttgttaaac aaggcagaga tgtaaaggga tagtcccttt ataattgagg tggcaccgcg
    77521 ttaccaacgc cctcacacgg aagtatattc tgtgtgtggg cttttttcta tccgtcgttt
    77581 ggtttatctt ttattagggc cttaagtcgc tttgatgaac ttgagttcta tctacagctc
    77641 catgcctact actaaaagca aacaaaaagg ctggactaat acgaaaaaag ctagtaatac
    77701 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgctcaaa accctgtttt
    77761 gaggttgtgg atagaactga cgaagtcagc tcaaaatact gttttgaggt tgtggataga
    77821 actgacgaag tcagctcaaa accctgtttt gaggttgcag atagaactga cgaagtcagt
    77881 aaccatacct acggcaaggc gacgttgacg cggtttgaag agattttcga agagtataaa
    77941 ggtgtaccga gatgaacatc tcttcatcaa tgtctttggt cgtggaggga aggacctagc
    78001 tgcgattgca gactacctag aagctaaaaa ataatagatg gaaaaattac agttctttct
    78061 ctcacagaga gcttgtggtt gctgaaaaca agcagagaaa gctgtaaagt tgggttcatc
    78121 tgaaacgaga gaagaaaaca tcattctcaa gggagtgccc tttatcgcac agcctgttac
    78181 aggagatatc tgagacagga atgagagata ggagaaatcc tataattgag gtggcaccgc
    78241 gaatttcgtc ctcacgcaag ttattttgcg tggggatttt tcatacagtc gccacgaact
    78301 agaagtagaa ctgaaaggga aattacaatg gaacgaatca ttcatggaga tgtcttatca
    78361 ccaatcttgg cttatatgcg cttaaagggg caacataagg ttattttaga gagtattccg
    78421 agagacaagg aaacagctcg tttttctatc ctagcctata atccagtttt tgagattaag
    78481 tttgaaaatg gagttctcta tcaaaatggt caagtgattg atcgggatcc cttggatttc
    78541 ctttatgaag tgattcataa gagtcagcac cactcagagc taccttttgg tggtggagcc
    78601 attggttttg tgggttacga tatgatttcg ctttatgaag aaattggtca aatccctgag
    78661 gatacaattg ggacgccaga catgcatttc tttgtctatg agagctatat ggtctttgac
    78721 cacaagaagg agaagataca tgtcatagag gatgcacttt atagtgagcg cagtcaagaa
    78781 gccttggaaa aatccttgaa ccaagtgctt gaggaattac gcattcctgc tccaaatgaa
    78841 tttgaagact tggatctatc tccgttagac ttcaaacccc atatcgctcc tcagaagttt
    78901 gaggaaatgg tggaaaccgc tcgcgacttg attcgtaatg gcgatatgtt ccaatgtgta
    78961 ctcagtcagc gcttctcagc agaagttact ggaaatccat ttgacttcta cagaaatctc
    79021 cgcgtgacta atccttctaa ttacctttat ttctatgatt ttggggatta tcaaatcatc
    79081 ggagccagtc cagaaagttt ggtttctgtc aaaaatggca tcgtgacaac caatccgatt
    79141 gcagggacgc gaccaagagg ggctacggat gaagaagaca aggccttggc gactgacctc
    79201 ctctctgatg agaaggaaac agcagaacat cgaatgttgg tagacttggg gcgtaacgat
    79261 attggccgca tctctgaaac ggccagtgtc caagttacta agtatatgga agtggagctc
    79321 ttccgttatg ttatgcattt gaccagcgtg gtcaaggggc gtttgcttcc agaactcact
    79381 gccatggatg ccttgaaagc aacgcttcct gctggaaccg tttctggagc accaaaaatt
    79441 cgagctatga gacgcatcta tgaactggaa acggaaaaac ggggcgtata tgcaggagca
    79501 atcggctact tgtctgcgac gggtgatatg gatttggcca ttgccatccg aaccatgatt
    79561 ctcaaaaatc aaagagccta tgtgcaggct ggggcaggga ttgtctacga ctctatcgcc
    79621 caaaacgaat accaagaaac cattaacaaa gcaaaatcta tgactagaat tggagaacta
    79681 agaccatgat tttattgatt gacaactatg attcttttac ctataacttg gcccaataca
    79741 ttgggaattt tgcagaagtt caggttctga gaaatgatga ttccaagctg tatgaagaag
    79801 ctgaaaaagc agatggtctg gtcttttctc ctggtcctgg ttggccagtt gatgctggaa
    79861 agatggaaga catgattcgt gattttgcag gcaagaagcc gattctaggg atttgtttgg
    79921 gccaccaagc cattgcagaa gtctttggtg gtaagctagg tttggctcca aaagtcatgc
    79981 atgggaaaca gagcaatatc aactttgaag cgccatctgt tttgtatcaa ggtattgagg
    80041 atggacgtgc ggtcatgcgt tatcacagta ttttgattga ggaaatgcca gaagactttg
    80101 aagtgacagc tcgttcgact gatgaccaag ccatcatggg gattcaacat aaaaacctac
    80161 cgatttatgg cttccagtac catccagaga gcattggaac gccagacggc ttgtcttcta
    80221 ttcggaattt tatcgagaag gttgtaaagt gaggaaacta ggatgaaaga gattattgaa
    80281 aaactagcaa aatttgaaaa tttatcaggt gtggaaatga cggatgtcat tgagcgtatc
    80341 gtaactgggc gtgtaactga agcgcagatt gcttctctcc tcttagctct taagatgaag
    80401 ggggaaacac ctgaagaacg cacagccatt gcccaagtca tgagaggaca tgcccagcat
    80461 attccaactg agattcatga tgctatggac aactgtggta caggtgggga caagtctttc
    80521 agttttaata tttccacaac tgcagccttt gtcttggctg gtggtggtat tcacatggcc
    80581 aagcatggta accgctcgat ttcttctaaa tctggttccg cagatgtcct cgaagccttg
    80641 ggaatcaatc ttgacctcaa accagctgaa ctaggtaagg tctttgataa aactggaatt
    80701 gtctttctct tcgctaaaaa tatgcaccca gctatgaaat acatcatgcc agctcgtttg
    80761 gaattgggaa ttccaacgat tatgaacttg actggtccac tgattcatcc aatggcttta
    80821 gaaacacagc ttcttggaat tagtcgtcca gaactcctag aaagtacagc tcaggttttg
    80881 aaaaatatgg gtcgcaaacg tgccatcgtg gttgctggac cagaagggtt ggatgaagct
    80941 ggcttgaacg gaacaaccaa gattgcactt cttgaaaatg gcgaaatcag cttgtcaagc
    81001 tttactccag aggatttggg aatggaaggc tatgctatgg aagatattcg tggtgggaat
    81061 gctcaggaaa atgcagaaat tttgcttagc gttctgaaaa acgaagcaag tccattcttg
    81121 gaaacgacag tcttgaatgc tggtcttggt ttctatgcta atggtaagat tgatagcatc
    81181 aaggaaggag ttgccttggc ccgtcaagtg attgctagag gcaaggccct tgaaaaactc
    81241 agactgttac aggagtacca aaaatgagtc aggaattttt agcacgaatc ttagagcaga
    81301 aggcgcgtga ggtggagcag atgaagctgg agcaaatcca gcctctgcgc cagacctatc
    81361 gcttggcaga atttttgaag aatcatcagg accgcttgca ggtaatcgct gaggtcaaga
    81421 aagctagccc tagtttggga gatatcaatc tcgatgtgga tattgtgcaa caggcccaga
    81481 cttatgaaga aaacggagca gtgatgattt cggtgttgac agatgaggtt ttctttaaag
    81541 ggcatttgga ttatctacgg gaaatttcca gtcaggtaaa cattccaacg ctcaacaaag
    81601 actttatcat cgatgaaaag caaatcatcc gcgctcgcaa tgcaggtgcg acagttatct
    81661 tgctcattgt ggcagccttg tccgaagaac gcctcaagga actgtatgac tacgcgacag
    81721 agcttggtct ggaagtctta gtggagactc acaatctagc tgaactagag gtagcccaca
    81781 gacttggtgc tgagattatc ggggtcaaca accgcaactt gactaccttt gaggtcgact
    81841 tgcagaccag tgtagattta gccccttact ttgaggaagg tcgctattac atttctgaat
    81901 ctgccatttt cacagggcag gatgcggaac gactagcccc atactttaac ggaattttgg
    81961 tagggacagc tcttatgcag gcagaaaatg tggcccagag aatcaaggag ttgcagattg
    82021 acaaaggtta aaatttgtgg actatcgacc aaagaagcgg tggaaacagc cgtttcagca
    82081 ggagccgact atatcggttt tgtctttgca cctagtaaaa gacaggtgac tttagaagag
    82141 gcagctgagt tggcaaagct tattcctgca gatgtgaaaa aggttggagt atttgtttca
    82201 ccaagtcggg tagaactgct ggaagcgatt gacaaagttg gcttggactt ggttcaagtt
    82261 cacggtcagg tggcagatga tttatttgag aatttgcctt gtgctagcat tcaggctgtg
    82321 caggtagatg gagagggtca tgtgcccaat tctcaggcaa actatctact ctttgatgcc
    82381 cctgtggctg ggagtggcca gccctttgat tggggtcaac tggatacgac tggattacct
    82441 cagtctttct ttatcgcagg tgggcttaat gaagacaatg tagtaaaagc aattcaacac
    82501 tttactccct atgcagtaga tgtatcaagc ggagtggaga cagatggaca aaaagatcat
    82561 gaaaagatta gaagatttat agagagggta aagaatggca tatcaagaac caaataaaga
    82621 tggattttac ggaaaattcg gcggacgttt tgtcccagaa acattgatga cagcagtttt
    82681 ggagttggag aaggcctacc gtgaaagtca ggcagaccca agtttccaag aggaattaaa
    82741 ccagcttttg cgccagtacg taggacgtga aactcctctt tattacgcaa aaaacttgac
    82801 ccagcatatc ggcggagcca agatttatct caaacgggaa gaccttaacc atacaggagc
    82861 ccacaagatt aacaatgcct taggacaagt ttggcttgcc aaacgcatgg gtaaaaagaa
    82921 aattatcgca gaaacgggtg ctggccagca cggtgtggca actgcaactg ctgcagccct
    82981 ctttaacatg gaatgtacca tctacatggg tgaggaagat gtcaaacgcc aagccctcaa
    83041 tgtcttccgc atggagcttt tgggagccaa ggtcgaggcc gtgacagatg gttcgcgcgt
    83101 gctcaaggat gcggtcaatg cagcccttcg ttcatgggtg gctaatatcg atgataccca
    83161 ctatatcctt ggttctgcct tgggtcctca tccattccca gaaatcgttc gtgacttcca
    83221 aagtgttatt ggtcgagaag ctaaacaaca gtaccgtgac ttgacaggtc gagatctgcc
    83281 agatgcccta gtagcctgtg ttggtggtgg gtcgaatgct atcgggctct tccatccctt
    83341 tgtagaagat gagtcagtag ctatgtatgg ggctgaagca gcagggcttg gtgtggatac
    83401 agagcaccac gcagctacct tgaccaaggg tcgtccaggt gtccttcacg gttcccttat
    83461 ggatgtgctc caagatgccc atggtcaaat tcttgaagcc ttctctatct cagcaggttt
    83521 ggactatcct ggtatcggtc cagagcattc tcactaccac gatattaaac gtgccagcta
    83581 tgtccctgtg acagacgaag aagccttgga aggatttcaa ctcttgtctc gtgtggaagg
    83641 gattatccca gctttggaat ctagccatgc tatcgctttt gcggtgaaat tggccaaaga
    83701 acttggacca gaaaagtcta tgattgtctg cctatcaggt cgtggggaca aggatgtggt
    83761 tcaagtcaaa gaccgcttgg aagcagatgc agcaaagaag ggagaagctc atgcctaaga
    83821 cactaacaga aaaattgaat gctattaaag cagctggaaa aggaattttt gttccctata
    83881 tcatggctgg tgaccacgag aaaggtttgg acggtcttgc tgaaacaatt cactttttag
    83941 aagatttggg tgtctctgca attgaagtgg gtattccctt ttcagaccct gttgcagatg
    84001 gacctgttat cgaagaagct ggcttgcgca gtttagccca cgggacctct acccaggctt
    84061 tagttgaaac cttgaaaacc attgaaacag agattccact ggtcatcatg acctacttca
    84121 accccctctt tcagtacggt gtggagaact ttgtcaaaga tctggctgat acagctgtga
    84181 agggcttgat tatcccagac ttgcctcatg aacatgccaa ctttgtagaa ccatttttgg
    84241 cagatacaga tatcgccttg attcctttag taagcttgac cacaggaatt gagcgccaga
    84301 aagagttgat tgaaggcgcg gagggattcg tctatgccgt tgccatcaat ggggtgacag
    84361 ggaaatcagg caattaccgt gcagatttgg acaagcactt ggcgcaactt catcaagtgg
    84421 ccgacatccc agtcttgaca ggttttggtg tatctagtca agccgatctg gaacgcttca
    84481 atgcggtgtc agatggtgtt atcgtcggtt cgaaaatagt aaaagctctc caccaaggag
    84541 agccgattca ggattttatc agacaagcag tagcttacca aaaataatca cacaagcagc
    84601 aagtaagagg aaaggcacga aaggaagtct ttcctttttc ttttgcagga gaaaggccag
    84661 gatacccgtc gcagaagcga actgaatcaa gatcagtaac tccgttacgc taaagacgag
    84721 agcgcaagaa gctaaaaaaa ggaaatcccc tgcacccatg cggatatcga taaaatgagc
    84781 caaaattcca agtatgagga aggagaccat gaccagattc cagccagagg aagctattag
    84841 gattaggtgg aaagtcatcc agaccagtaa gggatattcc tgatggcgaa agtcgtagat
    84901 acccaaggtc aaaccagcag tgattaggat gacttgactc aaggaaagta attcccaaga
    84961 gtaaagcaga aagaggagtc ctaagcctag ttcaaagagg gcataccaga caggatagcg
    85021 gaccttgcag tagcgacagc aaaagcgatt gaagacctgt gagagaatcg gaatcaaatc
    85081 taagggacgc aagcgagtct gacaggaatc gcagtgactg gctgaactga taatggattg
    85141 ctctggaaaa cggtcaatga ccaaaccaag aaaggaagcg agaatgctcc cgacgagaaa
    85201 aaaataaaaa tcaatcatac ttatctattc gtaaaaaatg ggagaaatag tataatggag
    85261 aaacatagat aagatggtga ggaaaagatg acaattcgtt ttgaagaaaa ggtgagtata
    85321 gaaaacgctc agctcgtatg ccaatggtcc aactccttag gcaaagtctt tcaagaacaa
    85381 tggatgggac caaggattcc ttttctactg acccttcaag ccttggaagg agtcttttca
    85441 atctttgatg aacaagagtt tgtgggactt atccagaaaa tcaggctaga agacagcaat
    85501 cttcatatcg ggagattttt tatcaacccc cagaaacagg agcaaggctt aggtagccag
    85561 gctttaagga aatttgttag tttggccttt gaaaatgaag atatagatag tatttctcta
    85621 aatgtcttcg aggcaaatca aagagctcag aatctttacc aaaaagaagg atttgaaatc
    85681 gttcaaatgg ttgaagcacc tgtacgaaaa tatagtagat tgaaactaga atagtacacc
    85741 tctacttcta aaacattgtt agaaatcgat ttgactgtcc cgatcgattc gtcctgttat
    85801 tatttcattt tactatacat tatgaaaaat gggagatagg agtataattc caaatataaa
    85861 gaaagcgaac aaaacagaat tctgattttc agaaaacagg tttattcgct ttttatgata
    85921 tactccctct ttttagccta tttattaaat gtaatagaaa attaagaatg tagaattgta
    85981 tgatacaaac aaagtgcaat agctgagtgt gcggctgtaa aatcattgta aggttcaata
    86041 atgacttcag gtaggcgatt atagagcagt ttgggtttgt agttcatttc actatatagt
    86101 ttttggatga tgtgttgatt tgttagtaaa ggactatgta ggtagatttt ttgagagtca
    86161 atcatcatac tgatatttaa aatggtttga ctaagataga gtaaggcttg atggataagt
    86221 gtgattattc cagtgtcacc taattgataa gcggttaaaa taacttggat atcaatatca
    86281 tcggcatttt tgactaaact aggaagtaga gaatagggag attgatgata tagaattttt
    86341 gattttttga ttaaccaaga ttctccagca aaagtttgta agcatccctt gcgcccgcag
    86401 ctacattctt ctccctcaga tgaaacaact gtatgcccta tttctccaat cattagattt
    86461 cctttcccat aaatgtttcc gtcgtagata taagaacagt gcatacctct agcaaaatga
    86521 aaataagcaa aattagggtc attctgttgg cgactaaata ggcgtttacc tatagccata
    86581 cagttaacat tgttagagaa aaacaaaggc ttatcaaagt gggattgaat catttctaag
    86641 tcgatatgtt gccataaagg attgtttgtt gttattttat aatcatctaa atagcgacca
    86701 ggtagcgcga ttccaattgc ttctatttca taatcagagc agttatttaa gaattgcttt
    86761 agtgtctggt taatgagttg atttcccttt tcttggatta actgtttagt aacaatttct
    86821 ttctcttcct ttaagatatt tcctagatta tctcctaaag caaaagtgaa atgtttttca
    86881 gatagttcac aaccaatgta gtaaaatcgt ttagcttgaa tgtctagcag gatttttttt
    86941 ctcccgacgc ttgtatcgtg ttcgtcttca ccaagttcta agagaatatt ttctttaatc
    87001 agatcatttg tgatactgct agttgttgca ggtgttattc ctgttttagt agcgatttca
    87061 attcgtgaaa tgggacctaa tgtgtaaact gtttccagta ttttagctct tagttgtaat
    87121 tgtttcttag ataaggtcat attagttttc ttcctagttg tcagattctt aaaatcctat
    87181 gattttttgc tatggataaa tgtagatgtt aatcttttta agcttttcat tacttactgg
    87241 tctcttttta ttatatattg ataataaaaa ataatcaaat gtttacacaa atccttgaca
    87301 aggctttctt atagttgtaa aatataaata acaaaagata atcaaataac aacttgacgt
    87361 caaaaaataa agataattga taacttttga taataaaata tatttaagag gaaaaggtta
    87421 tggaaaaatt attacaagaa aagttacttc cagtagcggc tagattgggt aataataaag
    87481 cgttggtttc tattcgagac ggtattactc taactatacc tttattgttg ataggttcat
    87541 tactaatggt tattgcaagt tttcctattc caggatggga aaaatatctg ggtgatattg
    87601 gtgttgctga ctatttatgg aagggtgttg atagtagttt tggattactt ggtcttgtag
    87661 ctagttttgg tatcgcttac tttatggcta gacaatacaa agttgatggt attcctgctg
    87721 gtattgtgtc attatcatct tttattacag ttacgccttt cattacagga gaggctggag
    87781 caggaatgcc taccgctttc atggcatcaa aaggtttatt tgttgctatg attttaggat
    87841 tgattaatgg ctatatctac caatggttta taaatcataa tatacagata aaaatgccgg
    87901 atggtgttcc accagcagta tctaaaagct ttagtgccat tattcctggt gcagtgacta
    87961 ttgttggttg gttgattgtt tatgcaactt tagataaatt aagtttacct aatcttcatg
    88021 aaattgctca agtagctttg ggaggtccac ttggactttt aggaaataat gttattggtc
    88081 ttcttatctt aattttcctt aatagtagtt tttggtttgt aggattacac ggaggaaatg
    88141 ttgttaatgc agttatgaaa ccgttatggt tagctaatct agatgcaaat aaagtagctt
    88201 atcaaactgg agaaactctt ccaaatattt ttactagcgt atttatggat aattttgtat
    88261 tcataggtgg cggtggtgca accataggtt tagttcttgc gttaggatat ttagcacata
    88321 agaagaaagc tagtaaacaa ctaaaaactt tggcacctat aactgttata cctggattat
    88381 ttaatataaa tgaaccagca atgtttggcg ttcctattgt tttgaacatt ttgttactag
    88441 ttccatttat cttagctcca atgtttaact tactagtagc gtggggagca atggcatcag
    88501 gtttggttcc gctaacttat acagatccag gttggactat gccacctgtt ataagtggtt
    88561 tacttgctac aggaagtatt tctggttcat tattacaaat tgtattgatt gttttggatg
    88621 tcttacttta tttaccattt gtaatagcta ttgaaaaacg gtttaagtta ttggaggatt
    88681 gagaatgaaa cgtttaatta gtgcaaatcc atctgagata ttacagatga atgctgaaga
    88741 attaaaacaa agtattttag caagtgaagg tagagttgtt ctatctgaaa atgtagttac
    88801 tcgtgagaca tttgttgggg atataactaa ttctgaaatt gctagagctt ttggagctga
    88861 tatgatttta ttgaattgtg ttgatgtttt tgagcctaaa atttatgctt tggatagttc
    88921 aggtgatgat gttattcatc gcttacacca gcttgttgct tgtccaattg gtgtaaattt
    88981 ggaaccgatt gacccatctg caaagatgct agaggaaaca caggaaattg ttgcaggtcg
    89041 tgttgctagt gttgaaacat tgaatcgaat agaggagtta ggttttgact ttgtctgttt
    89101 gactggaaat cctggaacag gagttagcaa tcgagaaatc attaaggctg ttcaaactgc
    89161 taaggaaaac ttttctggtt tgattattgc aggtaagatg cacggggcag gagtgaatga
    89221 gcctgtggca gagctttctg tcgcagagca attgttggaa gcaggtgcgg atgtgatact
    89281 tgttccagca gttggaaccg ttccagcctt tcatgaccaa gagttgcgtg aagtcgttga
    89341 tctcgttcat agtaagggtg gtcttgtatt gagtgctatt ggtactagcc aagaaacatc
    89401 tgatacagat actattaagg aaattgcact tagaaataaa atttgtggag ttgatattca
    89461 acatataggt gacgcaggat atgggggact ggcaacagtc gataatattt atgcattgag
    89521 caaggcaatt agaggagtga gacatacagt atctcgcttg gctaggtcag taaataggtg
    89581 ataaaggagt aagctatggc taaagtaaca attatgttag catgtgcagc aggtatgagt
    89641 acaagtctgc tagtgacaaa gatgcaaaag gcagcagaag ataaggggtt ggatgcagaa
    89701 atttttgcag ttccagctcc tgaagcagaa gaaattgtag caacaaaaga agtaaatgtg
    89761 ttgcttttag gcccccaagt tcgctattta ctaggggact ttcaagaaaa actaaaagat
    89821 agacagattc ctgtggcggt tattccgatg acagattacg gaatgatgaa tggttctaaa
    89881 gttttagatt tagctgaaag tttattagac taagattgag gagaatgtta tggatgaaag
    89941 taatttagaa tctgtaatgg ggctaattat gtatggtggg gatgccaaaa gtaatgctat
    90001 ggaggctatt caggcagcaa aaaaagggga tttctctaaa gccaatcgaa gattagctga
    90061 tgcgaatgct gccttattac aggcgcataa ggctcaaaca gaaatgttga caaaagaggc
    90121 acagggggaa gaaacatcaa ttagcctctt gatggtacac gcgcaagatc atttaatgac
    90181 gagtctgacc tttgttgact tggcgaaaga agtggtagaa gtatacgaac gatttgaaaa
    90241 aaattaggaa tttgctatga atacaatgtt ggataaaatg caagaaaaac tttctccaat
    90301 tgcaatgaaa gttgggaatc agaagttttt agttgcttta cgtgattcat ttgtggggac
    90361 tatgcctgtt attatgacag gttccattgc tttgttatta aatgcttttc tagtggattt
    90421 accacaacaa tttcacctag aaagtattac gaaaaccttt cagtggcttg ttgacatcaa
    90481 taatttggta ttcaagggaa gtataccaat tgtttcctta ttgttcatct attgcttggg
    90541 agtgaatatc gctaagattt ataaggttga tacagtttct gctggtttgg tatcgcttgc
    90601 ttcgtttgtc atttcgattg gaagtacagt tacaaagagt ttccctttgg caaatgtagg
    90661 agatgtgaaa ttagatcaaa tcttacaagg aattgataat ctagcatttg atggtaaaaa
    90721 tctgatggta actattggga atgtgattcc aggaaaccat attaatgcca gaggctactt
    90781 tacagccatg atgattggat ttttagcctc tattattttc tgtaaagtaa tgaaaaagaa
    90841 ctgggtaatc aagttaccag attcagttcc ccctgcgatt gctaagccgt tcacttctat
    90901 cattccagga tttatggcga tgtatatagt agccatcttg acttatgttt tccatttact
    90961 tagcaatgac ttattgattg attgggttta caaggtgtta caaacgccat tactaggttt
    91021 gtctcaaagt ttctttgcag ttattctgat gatcttttta aataagttat tctggttttt
    91081 tggtctccat ggaggaaatg tattggctcc catcatggaa gggctgtttg gagttgctat
    91141 gttagcgaat ctggatgctt tccaaaaagg tgaaccgatt ccttatatat ggacaagtgg
    91201 gtcttttggg gcgtttgtct ggtttggagg attaggattg gtacttgcta ttttaatttt
    91261 ttcaagaaac agtcattatc gaaaagttgc taaacttggt ctagcaccag ttctgtttaa
    91321 tattggtgag ccggtaaatt atggtttacc agttgtcttg aatcctttgc tatttatacc
    91381 atttgtactt agcccggttt tcatggcaac ggtagcttac tgggcaacaa gctggggtct
    91441 tgtttcacct gttacacaaa atgttacttg ggtaatgcct ccaattttat atggttgctt
    91501 ctctacagca tttgattggc gtgccatcat cttatcagtt gtttgtttga ttattagtgt
    91561 cttgacttat ttcccatttg tgaaaatggc agataaaact gaattgagtt aatggtctta
    91621 cttgcgtttt ttgtgataaa atagaaatag attacgtgta agattgagtt aggtgtagga
    91681 tttcttatct ccactaaaat tgttattaga caaaggttta tagtttattg aagttggaat
    91741 agtacactgt aacttctaaa atagtactag aaaatgattt gaatttccta atcgatttag
    91801 tcatatttta gttcattttt ctataaaaca taacaagaat gttattgttt tatatagaga
    91861 gattgatata gaaaggggtg cagtaaaggt agatatcttc ttgtgcctct tttgccatat
    91921 tagaaaggag attttatggt tcagacaaaa cagccaaata ttattttgat tgttgtagat
    91981 caaatgagag cagacgcctt atccttgaat agtaaggata agctagttag cactccaaca
    92041 ttagatatga tggctagtgt aggttataat tttgaaaatg cctattctcc agttccttct
    92101 tgcgttcctg ctagggcagc tttattgact ggcttagacc aagataaaag tggacgagtt
    92161 ggttatcaag atgaggtgcc ttggaatttt actaatactc ttccaaaagt ctttaaagat
    92221 atgggttatc aaacagagtg tattggtaag atgcatgttt ttccttccag acagagactt
    92281 gggtttgatc atgtcttact tcacgatggg tatctacatg ttgatagaaa gtatgataag
    92341 gcttatggaa gtcaatttga ttatgctagt gactatctag cctttttaaa gggtaaagtt
    92401 ggttatgatg ttgatttgat tgatgacgga atggattgta attcttggga agctagacct
    92461 tgggataaag atgagaagtt acatccaaca aactgggttg tgagtgagtc catttcattt
    92521 ttacaaagaa gagatccaac ggttcctttt tttctcaaaa tgtcttttga aaaaccacat
    92581 gctccattaa atcccccaaa atactatttt gatatgtata tggaacgctt gcctcaattt
    92641 ctcgatttgc acatcgggaa ttgggaagta ttagaaaagc aaattccgtc tatttatgct
    92701 ttaagaggga aattaaagga agatgatcaa agaagaatgg ttgctgctta ttttggattg
    92761 attactcata tagaccatca aattagtcgc tttttgactg ccctaaaaga atttcgtcat
    92821 gataaagata cgattatctg gtttgtttcg gatcatggag atcagcttgg tgaacattat
    92881 ctgtttagaa agggatatcc ttatcaggga agtatccaca ttccttcgtt tatttacgat
    92941 ccggctggat tgatagctgg taatagggga acaatcaagc aattagtgaa aattcaagat
    93001 atttttcctt cactcgtgga tttggcagga ggaactacta cagatgaact agatggacgg
    93061 agtgttaaga atttattatt tggacagtac gaggggtggc gaacagaatt tcatggtgaa
    93121 catgctttag gaaaagattc tagtcaatat attttgacag accagtggaa atttatctgg
    93181 tttcctgttt taaatcatta tcagttattt gatatgaaaa aagatccgca tgaaatgaat
    93241 gatttgtatc caagtgaaaa atatcaacct attgttcgtc agatgaagaa aaaattagta
    93301 gactttctta gatatagaga agaaggtttt gttgtggatg aagagttagt tcctgttgaa
    93361 ctttctaaaa taacgccaac tctaacgaaa acgggggata gtcaatcatg aaaatgaaaa
    93421 aaatcaaggg tgggacattt atgatgggaa caaattctga agagggcttt ttagatgatt
    93481 ttgaaggtct tcaagtcgct gttagtgtaa aggatttttc cattgcggat actccagtta
    93541 cgaatcaaga atttgctcaa tttgtgaaag aaacaggcta taaaacacta gctgagcgac
    93601 aagagtggtc ttttgttttt atattgttcg ttccggaggc agaaagggag ggatatcctc
    93661 atcctgctgg ggctccgtgg tggttacaag tttcgaacgc ttgctggaaa catccctacg
    93721 gtgagaatag taatctagtg ggtttagaag accatccagt agttcatgtt gctttagaag
    93781 atgcattggc tttctgtaat tggagcggaa tgtctttacc gactgaagca cagtgggaat
    93841 atgctgctag aggaggaaga caatctgaat atccttgggg agatactctt ttagaaggtg
    93901 gatattatca tgccaatact tggcaaggaa gatttcctta tgaaaatact gccttagatg
    93961 gatttatagg aacggctcct gtctatgaat ttttacctaa tgattttggt ctatatcaaa
    94021 tgattgggaa tgtttgggaa tggtgtcgca atccgagata taccttatta gctagtttta
    94081 atgaagatga ctatgagttg ccaaaatatg ggatacaaga tgaggagtat gctatcagag
    94141 gaggttcctt tttatgtcat tgttcttatt gtaatcgata ccgagtagct gctagaaatg
    94201 gatgtatttc tacttccact agtagccatc taggttttag atgtttgaaa gaataggatg
    94261 gacttaaaaa gtggttgaga ttatttattt tctaatcatt ataatagcta gtggattggg
    94321 ttctatatca ggcatgggtg gtggaattat aattaagcca cttatggata gttttggata
    94381 ccattcggtc agtgatattg ctttttattc tagtttctct gtttttataa tggcgattat
    94441 ttcaacaatc aaaagatttt cacaaagtaa agagataaaa tggagattga tttttacggt
    94501 atccttttct tctgttttag gaggatttct aggtcatctt atttttcaag ttttgttatc
    94561 tcaattatca gtacggctag tatccattgt tcaaatgatt ttactatttg tgatgctact
    94621 tgtatcattt gttttaacag attttaaaaa aacttatcaa tttgataaga taggattcta
    94681 tatgatttgt ggtcttctat tgggcttaat ttctagtttt ttagggattg gtggtggtcc
    94741 gctcaatgta tctttattga tggtgttttt ttctatttcg ataaaagaag caacgatgta
    94801 ttctcttgca attattttct tttcccagct gtctcatttg gctacaattg ttgtggttac
    94861 aggtttaaat cagtatcatt tagcacctgt tccagttatt tttcttgctt ctatatgcgg
    94921 aggggtattg gggacggttg tatcaaaagt cttacctgaa aattgggtaa gatactgttt
    94981 taaagggatg ttattctttg tcatgggaat gactttatat aatttgtttc atattttgta
    95041 aggtcagtgt gaaaatattt aaatagactt cctgtaaaaa ctggatttaa cgccctccat
    95101 ttgtcaaatt aagctagaca gtcttaccaa ctcagaaaat acctgatgag gtatttggta
    95161 tccaaaggat ttaggtggga tgtgatttct tgaggctggg aaaaagtctt taaaattaaa
    95221 aaatgcataa tatcaggtgt tggaaaaact ttgatactat gcattttatt gtgggaatat
    95281 ttatttcatt ttctcctgaa attgagtttt tacccagcct aaaattcttg actgacttcg
    95341 ttgaaatctg tctgctttgg caagtcatga caccttaaaa gtctatttga atgttcgttg
    95401 agacaccgct gtcttggaca tcctagattc gcaaaaaagc tctcactatc gtgatgattg
    95461 gaaatatctt tccattttga aaactctttt ccacagtcaa acgtaataga tttaaagagg
    95521 ttcactagaa attgtgccag ccacccttgg atggattctg ccatatcctt tgccttacga
    95581 ctcttggtct tcaaactgac aatcaattga ctatacctgt tcgctcacaa ataggagaga
    95641 actttttacg aaaatctaat gaatatgcca caagaacatt ataccgcaac gtgtactatt
    95701 tttggttcat tttactatag aaactattga agcacctgta cgaaaatata tcatgaaaaa
    95761 ggggagatag aaagcaaaca gccttgaaat caatgttgac tgcgattatg aacctgaatc
    95821 agcccctcaa aagggactgt atatgaatga acgttaccag tgtttaaaaa ctaaagaata
    95881 tcaggcactt ttatcttcca agggtagaca aattttcgct aaacgtaaga ttgatatgaa
    95941 atctgtcttt gggcagataa aggtttgttt gggttataag agatgtcatc tgagagggaa
    96001 gcgtcaagtg agaattgaca tgggattcgt actcatggcc aacaacctgc tgaaatataa
    96061 taagagaaag aggcaaaatt aaaggctcta taatatttgt agtgggtaaa tcccctatgg
    96121 atattatgga gcttattttt gtgtagaaaa aaagtcccat atgacctata atgaaaagcg
    96181 acaaaacaac tcattagaaa gaatcatatg gaacaattac attttatcac aaaactgctc
    96241 gatattaaag acccaaacat caagattcta gatatcatca atatggatac ccacaaagaa
    96301 attatcgcta agctggatta tgaggctcca tcttgccctg attgtggaag tctaatgaag
    96361 aaatatgact ttcaaaaacc gtctaagatc ccttacctcg aaacaactgg tatgccttct
    96421 agaattctcc ttagaaaacg ccgtttcaag tgctatcact gttcaaaaat gatggttgct
    96481 gagactcccc tggtaaagaa aaatcaccaa atccctcgta tcatcaacca aaaaattgct
    96541 caaaagttaa ttgaaaaaat ttctatgact gatattgccc atcagctttc catttcaact
    96601 tcaactgtca ttcgcaagct caatgacttt cactttgagc atgatttttc tcggcttcca
    96661 aagattatgt
//
LOCUS       DAVDFK010000003        95906 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.03, whole genome shotgun sequence.
ACCESSION   DAVDFK010000003 DAVDFK010000000
VERSION     DAVDFK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 95906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.03"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(394..1740)
                     /gene="gdhA"
                     /locus_tag="VUR04_000204"
     CDS             complement(394..1740)
                     /gene="gdhA"
                     /locus_tag="VUR04_000204"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET5340178.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVTWVDRNGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHGGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVDQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            2082..2306
                     /locus_tag="VUR04_000205"
                     /pseudo
     CDS             2082..2306
                     /locus_tag="VUR04_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2409..2820
                     /locus_tag="VUR04_000206"
                     /pseudo
     CDS             2409..2820
                     /locus_tag="VUR04_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            2823..3494
                     /locus_tag="VUR04_000207"
                     /pseudo
     CDS             2823..3494
                     /locus_tag="VUR04_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            3550..4068
                     /locus_tag="VUR04_000208"
     CDS             3550..4068
                     /locus_tag="VUR04_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET5340179.1"
                     /translation="MLSPAGAQESLSSYFVKITDASKAVKNGDQAEVQKLVTKMASDF
                     ERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLAFEKEQNPVDLDAEKEKLVNR
                     LSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNSTAHYGRVETAISFLPS
                     SMETEPTDESGT"
     gene            complement(4125..4409)
                     /locus_tag="VUR04_000209"
     CDS             complement(4125..4409)
                     /locus_tag="VUR04_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET5340180.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4463..5398)
                     /locus_tag="VUR04_000210"
     CDS             complement(4463..5398)
                     /locus_tag="VUR04_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET5340181.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQTDGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            5502..5945
                     /locus_tag="VUR04_000211"
     CDS             5502..5945
                     /locus_tag="VUR04_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET5340182.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            6061..6327
                     /locus_tag="VUR04_000212"
     CDS             6061..6327
                     /locus_tag="VUR04_000212"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET5340183.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            6324..6698
                     /gene="crcB"
                     /locus_tag="VUR04_000213"
     CDS             6324..6698
                     /gene="crcB"
                     /locus_tag="VUR04_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET5340184.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLRRKKW"
     gene            6692..7021
                     /gene="crcB"
                     /locus_tag="VUR04_000214"
     CDS             6692..7021
                     /gene="crcB"
                     /locus_tag="VUR04_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET5340185.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            7140..7487
                     /gene="rplS"
                     /locus_tag="VUR04_000215"
     CDS             7140..7487
                     /gene="rplS"
                     /locus_tag="VUR04_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET5340186.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            7529..7600
                     /locus_tag="VUR04_000216"
     tRNA            7529..7600
                     /locus_tag="VUR04_000216"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7562..7564,aa:Arg,seq:cct)
     gene            complement(7655..8461)
                     /gene="yidA"
                     /locus_tag="VUR04_000217"
     CDS             complement(7655..8461)
                     /gene="yidA"
                     /locus_tag="VUR04_000217"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET5340187.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(8474..9778)
                     /locus_tag="VUR04_000218"
     CDS             complement(8474..9778)
                     /locus_tag="VUR04_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET5340188.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSHIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            9850..10227
                     /locus_tag="VUR04_000219"
     CDS             9850..10227
                     /locus_tag="VUR04_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET5340189.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            10318..10650
                     /locus_tag="VUR04_000220"
     CDS             10318..10650
                     /locus_tag="VUR04_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET5340190.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            10662..12233
                     /gene="ffh"
                     /locus_tag="VUR04_000221"
     CDS             10662..12233
                     /gene="ffh"
                     /locus_tag="VUR04_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET5340191.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(12428..13711)
                     /locus_tag="VUR04_000222"
     CDS             complement(12428..13711)
                     /locus_tag="VUR04_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET5340192.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14014..14727)
                     /gene="rsmG"
                     /locus_tag="VUR04_000223"
     CDS             complement(14014..14727)
                     /gene="rsmG"
                     /locus_tag="VUR04_000223"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET5340193.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            14821..15381
                     /locus_tag="VUR04_000224"
     CDS             14821..15381
                     /locus_tag="VUR04_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET5340194.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            15383..16282
                     /gene="htpX"
                     /locus_tag="VUR04_000225"
     CDS             15383..16282
                     /gene="htpX"
                     /locus_tag="VUR04_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET5340195.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGVQKLFYTHPPISERIERLKQM"
     gene            complement(16326..17885)
                     /locus_tag="VUR04_000226"
     CDS             complement(16326..17885)
                     /locus_tag="VUR04_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5340196.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKAPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYTGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(18300..18440)
                     /locus_tag="VUR04_000227"
     CDS             complement(18300..18440)
                     /locus_tag="VUR04_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HET5340197.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            18610..19152
                     /locus_tag="VUR04_000228"
     CDS             18610..19152
                     /locus_tag="VUR04_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET5340198.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            19152..19781
                     /gene="nth"
                     /locus_tag="VUR04_000229"
     CDS             19152..19781
                     /gene="nth"
                     /locus_tag="VUR04_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET5340199.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            19992..20513
                     /gene="pyrR"
                     /locus_tag="VUR04_000230"
     CDS             19992..20513
                     /gene="pyrR"
                     /locus_tag="VUR04_000230"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET5340200.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            20532..21455
                     /locus_tag="VUR04_000231"
     CDS             20532..21455
                     /locus_tag="VUR04_000231"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET5340201.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQIPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            21505..22584
                     /gene="carA"
                     /locus_tag="VUR04_000232"
     CDS             21505..22584
                     /gene="carA"
                     /locus_tag="VUR04_000232"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET5340202.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            22897..26073
                     /gene="carB"
                     /locus_tag="VUR04_000233"
     CDS             22897..26073
                     /gene="carB"
                     /locus_tag="VUR04_000233"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET5340203.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(26349..27158)
                     /locus_tag="VUR04_000234"
     CDS             complement(26349..27158)
                     /locus_tag="VUR04_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5340204.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(27160..27963)
                     /locus_tag="VUR04_000235"
     CDS             complement(27160..27963)
                     /locus_tag="VUR04_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5340205.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(27973..29460)
                     /gene="tacF"
                     /locus_tag="VUR04_000236"
     CDS             complement(27973..29460)
                     /gene="tacF"
                     /locus_tag="VUR04_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET5340206.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVGIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            29796..30503
                     /locus_tag="VUR04_000237"
     CDS             29796..30503
                     /locus_tag="VUR04_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET5340207.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            30508..31530
                     /locus_tag="VUR04_000238"
     CDS             30508..31530
                     /locus_tag="VUR04_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET5340208.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIHYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            31547..32416
                     /gene="licA"
                     /locus_tag="VUR04_000239"
     CDS             31547..32416
                     /gene="licA"
                     /locus_tag="VUR04_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET5340209.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            32406..33284
                     /locus_tag="VUR04_000240"
     CDS             32406..33284
                     /locus_tag="VUR04_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET5340210.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLV
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            33296..33985
                     /locus_tag="VUR04_000241"
     CDS             33296..33985
                     /locus_tag="VUR04_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET5340211.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            34081..34929
                     /gene="dprA"
                     /locus_tag="VUR04_000242"
     CDS             34081..34929
                     /gene="dprA"
                     /locus_tag="VUR04_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET5340212.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            35811..36854
                     /locus_tag="VUR04_000243"
     CDS             35811..36854
                     /locus_tag="VUR04_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET5340213.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            37021..39108
                     /gene="topA"
                     /locus_tag="VUR04_000244"
     CDS             37021..39108
                     /gene="topA"
                     /locus_tag="VUR04_000244"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET5340214.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLTIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            39214..39573
                     /locus_tag="VUR04_000245"
     CDS             39214..39573
                     /locus_tag="VUR04_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET5340215.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            39666..40298
                     /locus_tag="VUR04_000246"
     CDS             39666..40298
                     /locus_tag="VUR04_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET5340216.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            40342..40998
                     /locus_tag="VUR04_000247"
     CDS             40342..40998
                     /locus_tag="VUR04_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET5340217.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            41016..41649
                     /locus_tag="VUR04_000248"
                     /pseudo
     CDS             41016..41649
                     /locus_tag="VUR04_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            41677..42111
                     /locus_tag="VUR04_000249"
                     /pseudo
     CDS             41677..42111
                     /locus_tag="VUR04_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
     gene            42123..43160
                     /gene="leuB"
                     /locus_tag="VUR04_000250"
     CDS             42123..43160
                     /gene="leuB"
                     /locus_tag="VUR04_000250"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET5340218.1"
                     /translation="MTKKIVALAGDGIGPEIMEAGLEVLEALAKKTGFVYEIDRRPFG
                     GAGIDAAGHPLPDETLKACREADAILLAAIGSPQYDGAVVRPEQGLLALRKELNLYAN
                     IRPVKIFESLKHLSPLKSERIAGVDFVVVRELTGGIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     SMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSEKGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVAMMLRDSFGRYEDAERIEHAVEASLAAGVLTRDIGGQTST
                     KEMTEAIIARL"
     gene            43157..43426
                     /locus_tag="VUR04_000251"
     CDS             43157..43426
                     /locus_tag="VUR04_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET5340219.1"
                     /translation="MKLDEKITLALLIWNVMIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTCGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            43430..43789
                     /gene="leuD"
                     /locus_tag="VUR04_000252"
     CDS             43430..43789
                     /gene="leuD"
                     /locus_tag="VUR04_000252"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET5340220.1"
                     /translation="MAGSSSEHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            43951..44521
                     /locus_tag="VUR04_000253"
                     /pseudo
     CDS             43951..44521
                     /locus_tag="VUR04_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            44845..46776
                     /locus_tag="VUR04_000254"
     CDS             44845..46776
                     /locus_tag="VUR04_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET5340221.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            46763..48078
                     /locus_tag="VUR04_000255"
                     /pseudo
     CDS             46763..48078
                     /locus_tag="VUR04_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
     gene            48253..49239
                     /locus_tag="VUR04_000256"
     CDS             48253..49239
                     /locus_tag="VUR04_000256"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET5340222.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            49303..49374
                     /locus_tag="VUR04_000257"
     tRNA            49303..49374
                     /locus_tag="VUR04_000257"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49336..49338,aa:Arg,seq:ccg)
     gene            49557..50255
                     /locus_tag="VUR04_000258"
     CDS             49557..50255
                     /locus_tag="VUR04_000258"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET5340223.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            50246..53785
                     /gene="smc"
                     /locus_tag="VUR04_000259"
     CDS             50246..53785
                     /gene="smc"
                     /locus_tag="VUR04_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET5340224.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLIRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKNRLGGIVGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     ELAADEASLRSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEKDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHSRLEFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            53782..54576
                     /locus_tag="VUR04_000260"
     CDS             53782..54576
                     /locus_tag="VUR04_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5340225.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            54576..55394
                     /locus_tag="VUR04_000261"
     CDS             54576..55394
                     /locus_tag="VUR04_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5340226.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDDHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            55398..56687
                     /gene="ftsY"
                     /locus_tag="VUR04_000262"
     CDS             55398..56687
                     /gene="ftsY"
                     /locus_tag="VUR04_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET5340227.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELAEEEKLEHE
                     GTVEENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(56733..58220)
                     /locus_tag="VUR04_000263"
     CDS             complement(56733..58220)
                     /locus_tag="VUR04_000263"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET5340228.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALSQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(58369..59109)
                     /locus_tag="VUR04_000264"
     CDS             complement(58369..59109)
                     /locus_tag="VUR04_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5340229.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(59109..61274)
                     /locus_tag="VUR04_000265"
     CDS             complement(59109..61274)
                     /locus_tag="VUR04_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET5340230.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            61447..62400
                     /locus_tag="VUR04_000266"
     CDS             61447..62400
                     /locus_tag="VUR04_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5340231.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVTMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            62477..64465
                     /gene="uvrB"
                     /locus_tag="VUR04_000267"
     CDS             62477..64465
                     /gene="uvrB"
                     /locus_tag="VUR04_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET5340232.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            64475..65038
                     /locus_tag="VUR04_000268"
     CDS             64475..65038
                     /locus_tag="VUR04_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340233.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            65004..65492
                     /locus_tag="VUR04_000269"
     CDS             65004..65492
                     /locus_tag="VUR04_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340234.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIDGLKVIGFISYGNFRDKTMQAGEIIALYVLKDYYGKGIAQK
                     LVKAALTALDSFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKMLELGKPIKERRMVFY
                     SK"
     gene            65565..66032
                     /locus_tag="VUR04_000270"
     CDS             65565..66032
                     /locus_tag="VUR04_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5340235.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLRS
                     SDEGEVSWVQKDQLPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(66029..66544)
                     /locus_tag="VUR04_000271"
     CDS             complement(66029..66544)
                     /locus_tag="VUR04_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET5340236.1"
                     /translation="MTKDRKQSLLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYVYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGRVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(66556..67083)
                     /locus_tag="VUR04_000272"
     CDS             complement(66556..67083)
                     /locus_tag="VUR04_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5340237.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAIFVILASSFGFLMAGYPMVIVFRAFSHIFFGTLGALYLQKFPDTL
                     DKPKSSWVFNFVLALIHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(67260..67823)
                     /locus_tag="VUR04_000273"
     CDS             complement(67260..67823)
                     /locus_tag="VUR04_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5340238.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTVFVLGGIFYLFGNVFDGNIQKLLATVI
                     STNSIAELVISAVLTLAIVPRLQTLKK"
     gene            complement(67807..68358)
                     /gene="coaC"
                     /locus_tag="VUR04_000274"
     CDS             complement(67807..68358)
                     /gene="coaC"
                     /locus_tag="VUR04_000274"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET5340239.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(68370..69059)
                     /gene="coaB"
                     /locus_tag="VUR04_000275"
     CDS             complement(68370..69059)
                     /gene="coaB"
                     /locus_tag="VUR04_000275"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET5340240.1"
                     /translation="MKILVTSGGTSETIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            69289..70959
                     /locus_tag="VUR04_000276"
     CDS             69289..70959
                     /locus_tag="VUR04_000276"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET5340241.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRTLRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            71288..72463
                     /gene="mutY"
                     /locus_tag="VUR04_000277"
     CDS             71288..72463
                     /gene="mutY"
                     /locus_tag="VUR04_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET5340242.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQAFMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            72518..73222
                     /locus_tag="VUR04_000278"
     CDS             72518..73222
                     /locus_tag="VUR04_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340243.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            73215..74564
                     /gene="vicK"
                     /locus_tag="VUR04_000279"
     CDS             73215..74564
                     /gene="vicK"
                     /locus_tag="VUR04_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET5340244.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            74566..75375
                     /locus_tag="VUR04_000280"
     CDS             74566..75375
                     /locus_tag="VUR04_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET5340245.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            75466..75708
                     /locus_tag="VUR04_000281"
     CDS             75466..75708
                     /locus_tag="VUR04_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET5340246.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            75710..75964
                     /locus_tag="VUR04_000282"
     CDS             75710..75964
                     /locus_tag="VUR04_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET5340247.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            76011..76754
                     /locus_tag="VUR04_000283"
     CDS             76011..76754
                     /locus_tag="VUR04_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HET5340248.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGVLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(77043..78029)
                     /locus_tag="VUR04_000284"
     CDS             complement(77043..78029)
                     /locus_tag="VUR04_000284"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET5340249.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINRSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            78223..80691
                     /gene="gyrA"
                     /locus_tag="VUR04_000285"
     CDS             78223..80691
                     /gene="gyrA"
                     /locus_tag="VUR04_000285"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET5340250.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            80691..81434
                     /gene="srtA"
                     /locus_tag="VUR04_000286"
     CDS             80691..81434
                     /gene="srtA"
                     /locus_tag="VUR04_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET5340251.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSETVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            81678..82475
                     /locus_tag="VUR04_000287"
     CDS             81678..82475
                     /locus_tag="VUR04_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET5340252.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIASGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            82623..82745
                     /locus_tag="VUR04_000288"
     CDS             82623..82745
                     /locus_tag="VUR04_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HET5340253.1"
                     /translation="MTRDFKFETLQLHAVQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            82767..83807
                     /locus_tag="VUR04_000289"
     CDS             82767..83807
                     /locus_tag="VUR04_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET5340254.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALVH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYYALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            83978..85252
                     /locus_tag="VUR04_000290"
     CDS             83978..85252
                     /locus_tag="VUR04_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET5340255.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            85262..86140
                     /gene="truB"
                     /locus_tag="VUR04_000291"
     CDS             85262..86140
                     /gene="truB"
                     /locus_tag="VUR04_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET5340256.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            86381..86683
                     /locus_tag="VUR04_000292"
     CDS             86381..86683
                     /locus_tag="VUR04_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET5340257.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKASSQERGRLAFLQMLAQTLQGFR"
     gene            86791..87429
                     /gene="udk"
                     /locus_tag="VUR04_000293"
     CDS             86791..87429
                     /gene="udk"
                     /locus_tag="VUR04_000293"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET5340258.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            87557..88897
                     /locus_tag="VUR04_000294"
     CDS             87557..88897
                     /locus_tag="VUR04_000294"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET5340259.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            88875..89087
                     /locus_tag="VUR04_000295"
     CDS             88875..89087
                     /locus_tag="VUR04_000295"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET5340260.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            89084..89959
                     /locus_tag="VUR04_000296"
     CDS             89084..89959
                     /locus_tag="VUR04_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET5340261.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            89952..90767
                     /locus_tag="VUR04_000297"
     CDS             89952..90767
                     /locus_tag="VUR04_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET5340262.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREHIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            90760..91191
                     /locus_tag="VUR04_000298"
     CDS             90760..91191
                     /locus_tag="VUR04_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5340263.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            91198..92865
                     /gene="recN"
                     /locus_tag="VUR04_000299"
     CDS             91198..92865
                     /gene="recN"
                     /locus_tag="VUR04_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET5340264.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEADIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            92867..93595
                     /locus_tag="VUR04_000300"
     CDS             92867..93595
                     /locus_tag="VUR04_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET5340265.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLFFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            93674..95497
                     /gene="lepA"
                     /locus_tag="VUR04_000301"
     CDS             93674..95497
                     /gene="lepA"
                     /locus_tag="VUR04_000301"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET5340266.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(95590..>95906)
                     /locus_tag="VUR04_000302"
     CDS             complement(95590..>95906)
                     /locus_tag="VUR04_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5340267.1"
                     /translation="LYQLLLFHFQNKESEKFFGLIEDNLKQVHPLFQTVFKTFLKDKE
                     KIINALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLS
                     QA"
BASE COUNT        29093 a        17254 c        21266 g        28293 t
ORIGIN      
        1 ataatagagc aactacagta gtagcttaaa aacatgatta aatcgctatt cttaggagta
       61 gcggtttttc tttttgttta atactctttg aaaatctctt caaaccacgt cagctttgcc
      121 ttgccgtact caagtacagc ctgcgactcg cttcctagtt tgctttttga ttttcattga
      181 gtataaaaag ggttaagtaa gtatagtaaa ttgaaataag atatgaacaa atcgattaga
      241 aaagtcaaat taatttctag aaatatgtta gaaattggtt tgaattccgc aatcaatttg
      301 ttcagttttt atttcattta attagaattt cccaactgtc taactcaact aaaaatcccc
      361 aatcgtagtg attgaggatt gagtaaataa atcttaaaca ataccttgtg caatcatggc
      421 atttgctaca ttttcaaagg cagcaatgtt agcacctgca aggtagtctt tatcaagacc
      481 gtatgtttct gaagtcgttt tagctgtgtt gaagatgttt gtcatgatgt ctttgagacg
      541 gccatcaact tcttcacgag tccatgagag gcgaagactg ttttggctca tttcaagagc
      601 tgaaacggct acaccaccag cgttggcagc ttttgcaggt ccgtagaaga taccattttc
      661 tttgtaaact ttgatggcat caaggtcgct tggcatgttg gcaccttcag atacacagat
      721 aacgccttga tcaaccaaac gtttagctgc ttcaccgttg atttcgtttt gagtcgcaca
      781 tggaagagcg atatcatagt taccagcgta agtccataca gaacctccat gataagtagc
      841 agttgctttt tcagctgcat actcagtcaa acgagcacga cgtttttctt taacatcaac
      901 caaaagatcg aagtcaatac cattttcatc gatgacataa ccatttgagt cagaaacaga
      961 aataacagtt gcaccgagtt cagttgcttt ttgaagagca tattgagcaa cgttaccaga
     1021 acctgaaata acgactttct taccagcaaa gctgttaccg ttagctttga gcatttcttc
     1081 agtatagtaa accaaaccgt aaccagttgc ttctggacga atcaagctac caccaaatcc
     1141 aagaggttta ccagtcaaga caccagcatc aaattggtta agacgtttgt attgaccgta
     1201 aaggtaacca atttcacgtc caccaacacc gatatcacca gcaggtacgt caagtgatgg
     1261 tccgatgtgt ttttgcaatt cagtcatgaa gctttggcag aagcgcatca cttcagcatc
     1321 tgttttacct ttaggatcga agtctgatcc acctttacct ccaccgatag gaagtccagt
     1381 caagacattt ttaaagattt gttcaaatcc gaggaatttc aagatccctt ggtttacagt
     1441 tgggtggaaa cgaagtccac ctttgtatgg tccaacagct gagttgaatt gaacacggta
     1501 accacggttt acttgaactt ttccattacg gtcaacccaa gtaacacgga aagaaatcac
     1561 gcgctcaggc tcagtaatac gtgccaagat attttcttcg atatactcag ggtgtttttc
     1621 aaatacaggt tccaaagtgt tgaaaaattc ttcaacagct tggaggaatt cagcctcgtg
     1681 cccgttacga gctttcacag tttcaaacac gctttggata tattctttag cagatgtcat
     1741 atcgttctcc ttttattgtc atattttatt acataagaca ttatagcaga attttttttc
     1801 actgtaaaga aaaaacagaa attttctaaa aattctttca attcagtttt ttggtttttt
     1861 tgaaaataga taaaaaaacg aacgtttttc ttggaaatat ctttctcaaa gacaaaatct
     1921 taaagtatgg tatgctataa gaaaagaaaa tgtttagcaa ttcagaaatc acttgttaat
     1981 ttatccgtga tatgttagat ttgccagtaa aactatgacc attttggagg aaagcaatat
     2041 ttataccaga ctaaaataaa aaagcattat ataatagtga tatgaaatca actaaagaag
     2101 aaatacaaac catcaaaaca cttttaaaag actctcgtac agctaaatat tataaacgcc
     2161 ttcaaatcgt tctatagtaa aatgaaacaa gaacaggaca aatcgatttc taacaatgtt
     2221 ttagaagtag aggtgtacta ttctagtttc aatctattat atttcgtctg atgggcaaat
     2281 tttataaaga gattatagaa cttttatagt ggtttgaaat aagatgtgaa caactctatc
     2341 aggaaagtca aattaattta tagaaatatt ttagcagcca aggtgtactg ttatagattc
     2401 aatacactat agactgtaat caaacaacga tttggcgaaa tgtaaaaaaa tatgaggagt
     2461 tcggactcga ctctctcctt caagaaacac gtggtggtcg taaccatgca tatatgacag
     2521 ttgaggaaga gaaagccttt cttgcccgtc atttgaaggc tgcagaggca ggagaatttg
     2581 ttacaattga tgccttattt caggcttata aaaaggagtt aggtcgttcc tacacacgtg
     2641 atgccttcta tcaactgttg aagcgccatg gctggcgaaa tattacgcca cgtccagaac
     2701 atcttaggaa agcagacgct caaaccattg tcgcgtctaa aaataaaatc tcaattcaag
     2761 aagacaagaa agcgctttaa aatcagtaga ccttttcata aggttcgctt gatgtaccaa
     2821 atagtacgcc catgcaaaag aatatctatt ttgttgtctt ggacctgcat acgacggata
     2881 gagataaaat tatccagcta ttcaaggatt ggacggatga cagttgggct caatcctcat
     2941 cgtttgacgc tgacttttgg tgtatctgca agtttcttga aaaggatgaa cttggaaaac
     3001 aagcgccctc gactgttcag ggatttacct ctatttccta aggagcaatt acgtgaaaaa
     3061 tatactggtg gagatattgt gattcatgct tgtgcagatg atgagcaaat tgcctttcac
     3121 gctattcgca atctcatccg taaggggaga aatgcggtgc cccctttggt aagaaaaatg
     3181 agtttgatga agtggatttg agtctcttac ctgatgattc gcatgtttgt ttggccaaag
     3241 aagtggataa gccactttta cgtcgttctt attcttactc agatggcatt gatgaaaaga
     3301 ctggtcagtt tgatacgggt ttgctcttca tttctttcca gaaggatcct gataactttg
     3361 ttaaggttca aactaaccta ggtgctactg ataagatgaa tgaatacatc actcacatag
     3421 gtagtggact ttttacttgc tttggtggtg tggagaaagg aggctacatt ggtcagaaat
     3481 tattggaagg ctaaaagctg gttgcttgtt ttagctttgt catttttaat tcttaattct
     3541 taattcttaa ttctttcccc agcaggtgcc caagaaagct tgagttctta tttcgtaaaa
     3601 atcacagatg catccaaagc ggttaaaaat ggtgatcagg ctgaggtcca gaaactcgtt
     3661 acgaagatgg catcagactt cgaaagagta gaaaataagg attctgaggt tggtaagatt
     3721 gttaaggaaa agttagctct atctggagat attactgaag ccaaactcac cgaaatttcc
     3781 tcagctctat tagcttttga aaaagaacaa aatcctgttg acctagatgc ggaaaaggaa
     3841 aaattggtaa accgtctaag tcctcgtttt gaaaccttag agcaggccat tgcctccaaa
     3901 gatttggaaa aagtccgaga agcttttaag aaaatgaatt ccacttggac catcaatgaa
     3961 agtgtggttc gtgacaatag tacagctcat tatggacgtg ttgaaacagc tatttccttc
     4021 ctgcctagta gcatggaaac cgaacctaca gatgagtctg gaacatgaaa acagcagttg
     4081 atttcaagaa acaaaaaaga acagccgaaa ctgttctctt atcattattt gagaccgtat
     4141 tttttgttga aacgatccac gcgtccatct gcttgagtga acttttgacg tccagtgtag
     4201 aatgggtgtg agtctgatga aatttccaca cggatcaatg ggtaagtttc gccttcgaac
     4261 tcaactgttt cgttagagcg ttttgttgaa ccgctaagga attggtaacc agtagttgtg
     4321 tccatgaaga caactgggcg atattctgga tggatatctt ttttcatttt gcaatatttc
     4381 ctttctgcca tggtctcttt gcgagccata gattgttacc atactagtct atcagattct
     4441 gaaaagtttg gcaagtattt tatcagtttt taagcaagtt ttttaacttt tggtagatga
     4501 tttcgttttc ttctaggcta taggaattag caccacttgc tagagggtgg cctccaccat
     4561 catgctcctt ggcaatttca ttgataggat ggactttact gcgtaagcga actcggtagt
     4621 ggccatcagt ctgttcgaca aaaattcccc agagactcac tctgtcaatg cgtccaggtg
     4681 caccgacaat ggctgcagtt tcagcatcgg ttacattgta ttgtttcaag acttcttgac
     4741 tcaggataac gcgagcagca ccattttcat ccacttccag atggtcgtag atgtagcctt
     4801 gcagtttagc aattttgtag ctcatagtgt ccattttgcg agtgagagcc gcaaagtcaa
     4861 agttatgttc tctcaaataa gcagccagac gaagagtccg tgcagtggta gaagggtaga
     4921 ggaagcgacc tgtatcaccg acaattcctg caaagagcaa ctcagcatcg cgatctgcca
     4981 aggctagttg ggttgtttgg gcaaataggg taatcatctc gctagcgcta cttgaactag
     5041 tatcgaccca agacaggtca ccgtatacat catcatttgg atggtggtca atcttaatga
     5101 gaaaatcacc ttgactatag cgcttatcat cgatacgagc agtattagct gtatcacaga
     5161 cgatgacaag tgcgccttgg taggctctat cttcaacaag atccatctca gccatccaag
     5221 taagagttgg ttcatcaaaa ccgacggctt tgatggtttt ttctgggaaa tgatgttcca
     5281 gcaaggcttt caatcccacc tgacttccca aggcatcagg gtctggtttc atatgacgat
     5341 gaatgataat ggtgtcgtat tctttaattt tttctaaaat ttgttggcaa atctccataa
     5401 ataacctcaa ttctttctca tttcattgta gcacaagaat ttttattttt aaaatgaaaa
     5461 agatgtgata taatggagaa agataaattg aggaggacga tatggcatta gcaaaaattg
     5521 tatttgccag tatgaccggt aataccgaag aaattgcaga tattgtagca gacaaattac
     5581 gtgacttggg cttggatgtt gatgttgatg aatgtacaac tgttgacgct tcagacttct
     5641 tggaagcaga catcgctatc gttgcgacct atacttatgg tgatggtgaa ttgccagatg
     5701 agatgatgga cttctacgaa gacctagcag atctcaactt gaatggcaaa atctacggag
     5761 tggtcggctc aggagatacc ttctacgatg aattctgtaa ggctgttgat gactttgacc
     5821 gtgtctttgt gtcaacagga gcagaaaaag gttcagagtg tgttaaagtt gatctttctg
     5881 ccgaggaaga agatattgaa cgcttggaac aattcgcaga agaattggtt gctaaagtag
     5941 gataagcata aaagtgcgct gatgtaatca atcagtgcat ttttcttatc gagagttggg
     6001 attttactag cctaattgat ggctttttga tacaataatt caaataaagg aggagactat
     6061 atggatttag atattattcg tcaagaaatc gatcaaatcg acgaccaaat tgtcaaactg
     6121 ttagaagaac gaatgcattt agttgagggg gtggttgctt ataagaaagc ttcaggtaaa
     6181 ccaattttag atactaagag agaagaagtt atttttgaaa aggttagaag tcgtgtagag
     6241 gacaagcgct atcaggagac tattgtcgca acgttttcgg acatactcaa acgttcgcgt
     6301 gattatcagg atcagaatat caaatgaaaa aagaacaatt ttatccgcta ggaatttttc
     6361 tagctgctat gttgggcgga cttgtccgat atctagtttc cacctggtta ccagccagtc
     6421 cagactttcc ttggggcact ctctttgtta actatctggg aattttctgc ttgatttatc
     6481 ttgtcaaggg ctatctggtc tataagggga ctagtaaggg cttgatttta gcactgggga
     6541 cgggtttttg cggaggttta acaacttttt ccagcctaat gcttgatact gtgaagctgc
     6601 ttgatacagg gcgttatctt agtttagtcc tgtatttgct tttgagcatc ggtggaggcc
     6661 tactcttagc ttattttcta aggaggaaga aatggtaatt gtctatcttg caattgcttg
     6721 tggtttcgga gcactcgtac ggtatttctt ttctcgctat aatcaagctt ctaaattgcc
     6781 actcggaacg ctcatagcta atcttttagg ttgtttttta attggagtat tctacaatca
     6841 tgtagagtct aaggaagtat atgctattct agcaacagga ttttgtggcg gtttaacaac
     6901 tttttcgacc ttgaatgacg aacttcaaag actgctaagt gataagaagg tcttttattc
     6961 ttacctgact ttgacttaca taggtggttt ggttgcgatt tttttaggaa ttttgctata
     7021 aatttcttta cttttttgtg aaaatttggt aaactgtatc ttgtgtgtaa tggacgcaca
     7081 agaatacagt ttatccgctg aggaagtttc ctcaagattg acaaagatag gagaataaaa
     7141 tgaatccatt aatccaaagc ttgactgaag gtcaacttcg tacagatatc ccatcattcc
     7201 gtcctggtga cactgttcgt gtacacgcga aagttgtcga aggtaaccgt gaacgtatcc
     7261 agatttttga aggtgttgtt atcgcacgta aaggtgctgg aatctcagaa aactacacag
     7321 ttcgtaaaat ctctaacggt gtaggtgttg agcgtatctt cccaatccac actccacgtg
     7381 ttgaaaaaat cgaagttgtt cgttacggta aagtacgtcg tgcgaaattg tactacttgc
     7441 gtgctcttca aggtaaagca gctcgtatca aagaaatccg tcgttaattc gactaaaaaa
     7501 ctctgctttt cagcagagtt tttatctagc tcccttagtt caatggatat aacaactccc
     7561 tcctaaggag tagttgcagg ttcgattcct gcagggggca gtaattagac atcaaaaacc
     7621 gctcagctga gcggttttta tctattcttt ccttttacag tacccatgta cgaatagcat
     7681 gggcaacgcc ggattcgtca tttgttttgg tgatgtattt ggcgattttt ttgatttctg
     7741 gatttccgtt ttccatgact acagggttgc caacgacttc cagcatggca cggtcatttt
     7801 cttcgtctcc gatagccatg gtttcatctt tggttaatcc tagtttttca gctaagtgag
     7861 taatagctga acccttgtct acattctttt taaggagttc gaggtagaaa ggagcagatt
     7921 tgttgataga gtagtgctcg taaaattcgg ctggtatttt ttcaatcgca gcatcgagga
     7981 tttctggttc atcgatgaac atacacttga caatttcctt gccagccatt tcttcagggg
     8041 tacggtagaa gataggcatg ctgacgaggg ttgattcgtg tacagtgtat tttccgatat
     8101 tgcgatttgc agtatagata ccgtccttgg taatggcatg catgtggaca ccgagcttgc
     8161 gactgaggaa ttccatatcc agataatcct cataggtcaa ggattcgctg ataatctcat
     8221 ggccagtagc agtttcttgg acaagggcac cattgaaggt caccacatag tcaccttggt
     8281 ctctcaactg caagtcgtcc agaagtttgg caacacctgc gatggggcgg ccagttgcaa
     8341 tcacgacttt gacaccagct tctttggcat cttggatggc agaaaagact tcaggagtga
     8401 tttccttttg gctgttgact agggttccgt caatatcgac ggcgattagt ttaatactca
     8461 taaatttcct cttttagttt ttatttgggg taaaatgatc gttctcaatc aagtgtaaaa
     8521 attgctgggt gatgcttgcg aagatgctgt tttggtctaa catttctttc gggaaataaa
     8581 agcgattatc tccgtggcga cttccagcaa gggattggac gataggggac aggctagaga
     8641 gttctgccag ttctccattt ttttgtaaaa tctcaatctg tgtccttgga ttttcagatt
     8701 cgggacggta aatatcataa gggaggtcaa agttcttatg aatggcagta tagtagtcgg
     8761 gatcaaagcc gatgtcctca accaattttc tcatgctagc gagttggtct tggtcttctt
     8821 gtgaaaaggt aatggattta aagaccttgc ggttgacaaa gcgatgcgat aaatctgcaa
     8881 gaatcttgtc aggactggtc atccaaagct ggaagtaggt attcatcacg ccatcatcca
     8941 gagccagata gtcagtcaag gtcacatttt tttcgaagaa aggcaggagg tgtggagaag
     9001 ttcgggcaaa gaaatccttg tcctcaggat agagttcctt ggcgcgtttg agaagattct
     9061 gtaggagaac ttccatggca cgtgttgcgg ggtggaaata aacctgcatg tacatctggt
     9121 agcgactgag gacgtagtct tcgatggcgt gcatgccatt gcgctgaaag gcgataccat
     9181 tttcgatagg acgaatgact cggaggattc gagtcaggtc aaattcccca taggatgctc
     9241 ctgtaaaata ggagtcgcgc aagagatagt ccatgcgatc tgcgtcaata tgactagaaa
     9301 tgagctgcac gacctgctta ttaggatagg tatggtcaat gacactggcc accttttctg
     9361 ggaaatcagg tgccacttgt agcaggactt ggtgaatctc tgtctcagga ttttgaataa
     9421 tctcctgagt aatggcttca tggtctgtat caaagagatt ttcaaaagta tgggagtagg
     9481 caccatgccc aaggtcgtgt aggagagcag cggtcatggt caagagagac tcggcaggat
     9541 tccattcctc aggatatttt tcttcgaaaa tctctgtgat gcgtcgtgca atttcataga
     9601 ctcctagaca gtgagagaag cgactgtgtt ctccaccgtg gaaggtataa ctggaagttc
     9661 ccagttgttt gatccggcgc aaacgctgaa attcttttgt attaatcaag tcatagatga
     9721 tttgattatt gacatggatg tagttgtgaa cagggtcacg gaatactttt tcgttcatat
     9781 gaccattata gcaaaatcct gctctttttg gtaaaatagt aggacaagag acaagaaaga
     9841 gggcctgatg tgaagattcg gatgcgaaat acaattcagt ttgatgagca gttggaagtg
     9901 attgaccagc tttatgatgt ggaagtgcat gaaaaaggag attatagcta cctgcttttc
     9961 tataatgagg aaaaggaaaa agtagtgatt aaatttcatg gtcaagaact tgtgatgagt
    10021 cgattttcca atcccaagac cattatgcgc tttctaaagg atagtgatag tttagcctat
    10081 attcccacac ctatgggtat gcaggagttt attatccaaa cgaatcgtta tcaagtggat
    10141 gggcaaaaga ttgaactaga ttatcaacta caaaatcaag agggacatcc ctttgccagc
    10201 tatcaattgg aaattacttg gggctaggct catgtctttt tcaaatttag ctatctatct
    10261 tcttggatcg gcttcctagt gtggtagatt aggctaattt ttggtataat aaaagttatg
    10321 gaaatcgaaa aaaccaatcg tatgaatgcg ctctttgaat tttatgcggc gcttttgaca
    10381 gataagcaaa tgaattatat cgagctctac tacgctgatg attacagcct tgctgaaatt
    10441 gccgaggagt tcggtgtcag tcgtcaggct gtctatgaca atatcaagcg aacagaaaag
    10501 attctggaag attatgagat gaaattgcac atgtactcgg actatattgt ccgcagtcag
    10561 atttttgatc agattttgga gcgctatccc aaggataact ttctgcagga gcagatagaa
    10621 attttaacaa gcattgataa tagagaataa gaggaagaaa aatggcattt gaaagtttaa
    10681 cagaacgttt gcagaacgtc tttaaaaatc tacgtaaaaa aggaaaaatc tctgaatctg
    10741 atgtccaaga ggcaaccaaa gaaattcgct tggccttgct cgaggccgac gttgccttgc
    10801 ctgttgtaaa ggactttatc aagaaagttc gtgagcgtgc agtcgggcat gaggtcattg
    10861 atacacttaa tcctgcgcaa cagattatta aaatcgttga tgaggaactg acagccgttt
    10921 taggttctga tacggcagaa attatcaagt cacctaagat tccaaccatc atcatgatgg
    10981 ttggtttaca aggggctggt aaaacaacct ttgctggtaa attggccaac aaactcaaga
    11041 aagaagaaaa tgctcgtcct ttgatgattg cggcggatat ttatcgtcca gctgccattg
    11101 accagcttaa gaccttggga caacagattg atgtgcctgt ctttgcactt ggaacagaag
    11161 taccagctgt tgagattgta cgtcaaggtt tggagcaagc ccaaactaat cataacgact
    11221 atgtcttgat tgatactgcg ggtcgtttgc agattgatga actcctcatg aatgagcttc
    11281 gtgatgtgaa agcattggct caaccaaatg aaatcttgct tgtcgttgat gctatgattg
    11341 gtcaggaagc agccaatgtt gcgcgtgagt ttaatgctca gttggaagtg actggggtca
    11401 tccttaccaa gattgatggc gatactcgtg gtggtgctgc tctgtctgtt cgtcacatta
    11461 ctggaaaacc aatcaagttc actggtacag gtgaaaagat tacggacatt gaaaccttcc
    11521 acccagaccg catgtctagc cgtatccttg gtatggggga tatgctcact ttgattgaga
    11581 aagcttctca ggaatacgat gaacaaaaag cccttgaaat ggctgagaag atgcgcgaaa
    11641 acacctttga ttttaatgat ttcatcgatc aattagatca ggtgcaaaat atggggccga
    11701 tggaagactt gctcaagatg attccaggta tggccaacaa tccagccctt caaaacatga
    11761 aggtggatga acgccagatt gctcgtaaac gtgccattgt gtcttcgatg acacctgaag
    11821 agcgtgaaaa cccagatttg ttaaatccaa gccgtcgccg tcgtattgct gctggttctg
    11881 gaaatacatt cgtcgaagtc aataaattca tcaaggactt taaccaggct aaacagctca
    11941 tgcagggtgt tatgtctggg gatatgaata aaatgatgaa gcaaatgggg attaatccaa
    12001 ataaccttcc taaaaatatg ccaaatatgg gaggaatgga tatgtctgcc cttgaaggaa
    12061 tgatgggaca aggcggtatg cctgacttat cagctctcgg aggagcagga atgccagata
    12121 tgagccagat gtttggtggc ggtttgaaag gtaaaattgg tgaatttgcc atgaaacagt
    12181 ccatgaaacg tatggctaac aaaatgaaga aagcgaagaa gaaacgcaag taagacaaga
    12241 gattgatgca aatctcattt gatgagaaaa taaagtaaaa atttctatga taaaacgtac
    12301 agtatcaagg ttttagaata tctgatatta tacgtttttt gattttaata attttgttaa
    12361 gacactttta ttatggtatg cgaaaaatcc actcagctgt ctgagtggat taggtgtatt
    12421 tagactctta gtctttattt tcgtatggca agatcaagtt caagatgatt cctgtcatgg
    12481 ctgaaagggc agtacctgaa agtgtaactg gaccaagttt aaggatagct cctccaagtc
    12541 caagaaccaa catagcactt gcgatgatga ggtttcgcat ttgagcgaaa tcaacacgtt
    12601 ctttaatcaa gactttcaaa ccattgctgg cgataacccc atagagaagg attgacatac
    12661 caccaagtac agcgtttgga atagttgaaa tcaaggcagt gaatttacca aggaagctga
    12721 gggcaatcgc gatgaaggca gcgttacgga taactgagac agaagcgata cgagtcatac
    12781 cgataacccc tgtattttct ccgtaagttg tattggctgg tccaccaagg aaggcagaaa
    12841 cagaagttgc gataccgtca ccaagaagag tacggtgaag acctggttct tttaagaatt
    12901 gacgaccaca gatttgaccc aaaacagtat ggtctccgat atgttcagaa attgttacga
    12961 tagcgattgg caagatagcg atggcttctg gaccaaagta aagattgtac tctttaaagg
    13021 caccacctgt gctaaatggc aagtagaaac caggaatttc gaaccagttg gctttaagaa
    13081 ctggtgtaaa gtcaaccaag ccaagagtta gtgcgaaaag gtaaccaccg ataatggcaa
    13141 agaggaatgg aatgattcgt aggaagcctt ttccttttgt attgataaag gcagcaatta
    13201 ggaaagtaac aacggctacc agagcatttt tccaatttcc gtctgctaca agacctgcat
    13261 tggtaacagc tgaacctgca agtccaagac cgataacgat gatcatagga ccgataatga
    13321 ttggtggcaa gagtttatca atccattttg ttcctacaaa tcggatgctg gtagcaacaa
    13381 ggacatagac caaaccagtc aagataaccc ctgtttgggc agcagataca tcccccccca
    13441 tttctttcat agccagtgac atagctgtga taaaggcaaa tgaagaacct agataaactg
    13501 gaactttaaa accagtagca atcatgtaga tgagtgttcc aacacctgaa gcaaaaaggg
    13561 caacagatac aggcattccc aaaatcaatg gtaccaagat ggtcgcacca aacatggcga
    13621 aaacgtgttg gaaactaagg agaattcctt ttccatccga aggacgttgg tcaacgtcta
    13681 gtaacaaatc aacagttgat tcttgtttca tataaacctc acttttgggc atcagaaaag
    13741 agcccattat tttacagcaa taggccctca gagtaagact tctctaaaat ctagacttta
    13801 aagagtttca aatatttctg cgtcttcgtc acctcacggg atgacattaa aaacctttgc
    13861 ttaggatagt atagcagaaa aaaatgattt tgtaaatcat tttttcccga gcctagaaat
    13921 aaaagagcga ggctgatttt gtaaatcatt ttttcccgag cctaaaaata agagagcgag
    13981 gttgattttg taaatatttt tttacttaaa aatttaaagc gggcgtttat ttggcatacc
    14041 agccttacgt ggatatttat ttggtgtttc ttttttcttt tctaccactg tgatgtaacg
    14101 cggatctcta tttggtaggg cgtagctgag attgtcttcg actttactaa aaaggagatt
    14161 gagggcattc ttagcttcta acaactcctc aggcgcattg ctggccttga gtgccaatag
    14221 ttttccacca accttaaggt agggaatagt caattcagat aggacctgca tacgggcaac
    14281 cgcacgagct gttacaaaat catattgagc acggaagttc ttgtcttggg caaaatcttc
    14341 ggcacgtccg tggtagaaat gaactccgtt caaatccagt tcttgagcca agagttgtag
    14401 gaagttgatg cgcttattga gtgaatcaat aatggtcaca tctaactccg gatagagaat
    14461 tttcattggt agactaggaa atcctgcccc agccccgata tcaagaagtt tgatagtttc
    14521 attgggaatc aaaccttgaa gaatgggtgc aatcgaatcg taaaaatgtt tgagataaac
    14581 ttcttccttg tccgtaatcg ccgttaaatt aatcttctca ttccactcga ccaagagctc
    14641 aaaataacgt tcaaattgtt ctttttgctg gtccgaaagt ggaagattct gctcggcaag
    14701 caagttgtaa aatgtttttg gtttcatagt tatttccttc tttagtatca tcttatttta
    14761 ccacaatcat agaaaatttg atatactggt actaatctaa aagcagaaag gacttatatt
    14821 atgacttgga ttattcttgg agttttagct cttgttgtta tttttgtgat tgttagctat
    14881 aacggtttgg ttaaaaatcg tatgcaaacc aaggaggctt ggagtcagat tgatgttcag
    14941 ttgaaacgtc gcaatgatct cttgccaaac ttgattgaga ctgtaaaagg ttatgccaaa
    15001 tatgaaggtt ctacccttga aaaggtggca gaactacgta accaagtggc ggcagcgact
    15061 tcaccagcag aagctatgaa agccagtgat gccctcactc gtcaggtttc aggtattttt
    15121 gcagttgcag aaagctatcc agatttgaaa gctagtgcta actttgttaa attgcaagag
    15181 gagttgacaa acacagaaaa taaaatttct tactctcgtc aactctataa cagtgttgtc
    15241 agcaactaca atgtaaaatt agaaactttc ccgagcaata ttatcgctgg aatgtttgga
    15301 tttaaagcgg cagatttcct tcaaacacct gaagaggaaa agtcggttcc taaagttgat
    15361 tttagcggtt taggtgacta agatgttgtt tgatcaaatt gcaagcaata aacgaaaaac
    15421 ctggattttg ttgctggtat ttttcctact cttagctctt gttggttatg cggttggtta
    15481 tctctttata agatctggac ttggtggttt ggttatcgca ctgattatcg gctttatcta
    15541 cgctttgtct atgatttttc aatcgacaga gattgtcatg tccatgaatg gagcgcgtga
    15601 ggtggatgag caaacggcac cagacctcta ccatgtagtg gaagatatgg ctctggtcgc
    15661 tcagattcct atgccccgtg ttttcatcat tgatgatcca gccttaaatg cctttgcgac
    15721 aggttctaat cctcaaaatg cggctgttgc tgcgacttca ggtctactag ctatcatgaa
    15781 tcgtgaagaa ctagaagctg ttatgggaca tgaagtcagt catattcgta attatgatat
    15841 ccgtatttcg actattgcag ttgcccttgc tagtgctatc accatgcttt ctggtatggc
    15901 aggtcgtatg atgtggtggg gtggagcagg tcgcagacga agtgatgatg accgagatgg
    15961 aaatggtctt gaaatcatta tgctagtggt ttccctacta gctattgtac tggcacctct
    16021 cgctgcaacc ttggttcagc tcgctatttc tcgtcagagg gaatttctgg cagatgcatc
    16081 tagtgttgag ctgactcgca atccccaggg aatgattaat gccctagata agttggacaa
    16141 tagcaaacct atgagtcgcc acgtcgatga tgctagcagt gctctttata tcaatgatcc
    16201 caagaaaggt gggggggtcc aaaaactctt ttatacccac ccacctatct cagaacggat
    16261 tgaacgttta aaacagatgt aaaagaatcc agaggtcgtc tctggatttt tgctatgttg
    16321 caaatttata catcttctaa attaactaac tccaaaccgt gttctgtcaa gcggtagatg
    16381 cttgaacaga cctcttttaa gaaacgacgg tcatgcgaaa cagtgatgag accgcctgta
    16441 taggttgcaa agagttttct gatttggggt tgagaagtgg gagaaaagtt tcgtgtgggt
    16501 tcatccagca ggagaaagtt tggtttgcgc aggactaaat ccaaaagcag gagttttccc
    16561 tgttgtccgc cagataagga gcgaatttga tgctgcattt ctggataact gaaattgaga
    16621 ctagctaggt gagattggat tttctgtagt tcctcttttt ccccagtttt gctgaggtag
    16681 gctattggtg ataaatccaa ttgcagtttt ttgtggtaat cttgtggcat aaaaccaagg
    16741 gaaatctctc ttttatcatt cagaagttgc tttaatttgg ctaacagagt tgatttccca
    16801 acaccatttg gcccgataat accgattttt tcttggccac ggacagttag ttgtagtttt
    16861 tgaaccaaaa ctcggtcgtc aatggacaaa ttttcttttt ccagttggac taagacttta
    16921 gaagctggta atggttggat gtctgaaaag aaaagttgga tttgttcctc ttcaagtggc
    16981 ttttgagtca tggactgagc tgccttttcg tagcgttttt cttgtgagag gacagttttc
    17041 atctttttag ccaataggcg accggcagta ctatctttgg tagctcgaag cgcagtttct
    17101 acactttgct tgactctccg atgtttttcc atggttttat cgtaggctct ttggttgtta
    17161 gcagcttgct gactttgttt ggcaaaatta gcctttctct gctcactata gctatcatag
    17221 tctaaatgct ctactagcgt ttccgcttct ttacggtgtt tgaccagtcg caagtgaaca
    17281 atagtgtctg ccgtttcaga aagaaagtct tcatcatggg aaatgaaaat aacggtttgc
    17341 ctggtctttt gaatctggcc ttttagccaa tcaactgtct caaggtctag gtcatttgaa
    17401 ggttcatcta aaaatagaat ctcaaagggt ttggctaact catggataag ctgaattttc
    17461 aaagcttcgc cccctgatag attgccaatc tcttggtcac ttgcgaaacg attgctatca
    17521 aaatgcaatt cctccgccaa acgatagagg atactgtagt ctaaatcaat agaatctaaa
    17581 aagaagtagt cgtgtaaagt tttctttttt aggtcctcag gggctttttg aggaatgtag
    17641 gccagtgact gataatcaga ctggatgtct cccttgatag tgaaatcaga caaatcttcc
    17701 cccattaaag ttttaagtaa ggttgattta ccatttcctt cttcgccaat aatagctacc
    17761 ttttccccgt cttggatggt catggttagg tcagatacaa gatctcgtaa atctttgttt
    17821 tgtgtgatgg ttagatgatt gatttttatc atatgatttc cctttctaga atgttcatag
    17881 tgcataacaa aaagctctac tttacctagt agagcccaaa gtctatgtca aaaaaactct
    17941 attaacatgc cagaaaaaga gcataaaaga gcacacaaaa agagacaaaa acaagatcta
    18001 ctaaataaag gttctttatt tgatagactt agttgttcat gtctccctta cctcctagta
    18061 ttagtatctt tatactatac ttttaaggaa attttgtcaa cagaaaactg gaaattctat
    18121 gctctaaaat ccaaaaacag gtccatagag acttagtacg tgtttgacat gctcgtaatg
    18181 gattttatca tagtttcgcc aagcagtgcg ttcttgattg tttagtttta ggctacccag
    18241 tccaatcaga ggactggtgg gttggtaaaa tttctcaaga tcaattaaga tactgttgtt
    18301 caacttttct gttttttgag ctcttgcata gtagtgttta gcagctcttg tagtcgaata
    18361 tcatctgccg taccctgttt acagttttgg tagcttttat ttaacttgga taggagttga
    18421 atgagtttct tgtcttccat gtgagcatcc tccttgatct gatgtactct ttccctatag
    18481 tatagcacta aaaaataaaa atgtaatagt aaatatgtta aaattttgaa ttttaattac
    18541 aaagtttggt gtgctgattt gtagcctttt catggtataa tcaagagagt aaatctttat
    18601 ggaggaagta tgaaattaaa tattcaagaa attcgtaagc agtctgaagg tttgaacttt
    18661 gaacaaacgt tagatttagt tgatgacctg cgtgcacgta atcaagaaat tttagatgta
    18721 aaagatatcc ttgcagttgg gaaagtacaa tatgaagacc gtatgtattt cttagattat
    18781 caactatctt ataccattgt tcttgcttcg agtcgcagta tggagccagt tgagttagtt
    18841 gaatcttatc cagtcacgga agttttcatg gaaggcgcaa ctaaccatct aaatcaagaa
    18901 attttagatg atgacttggt cttgcccatc gaaaatgggg cgcttgacct tgctgagagt
    18961 gtatcagaca atatcctgct aaacattcct atcaaggtct tgacggctga agaagaagct
    19021 ggtcaaggat ttgtctcagg aaatgactgg caaatcatga cagaggaaga ataccaagct
    19081 caacaagcag taaagaaaga agaaaacagt ccttttgctg gcttacaagg actatttgac
    19141 ggagatgaat aatggtcttg tcaaaaaaac gagcacgaaa ggtgctagaa gaaatcattg
    19201 ccctcttccc agatgccaag cctagtcttg attttaccaa tcattttgaa ctcctggttg
    19261 cggtcatgtt atcagcccag acgacagatg cagcggtaaa taaggccaca ccaggtctct
    19321 ttgttgcctt tccaacaccc caagctatgt ctgtagcgac agagagtgag attgcttcac
    19381 atatttctcg cttgggattg tatcggaata aagctaaatt ccttaaaaaa tgtgcccaac
    19441 agttactaga cgattttgat ggtcaagtcc ctcagacacg tgaagaattg gagagtttgg
    19501 caggtgttgg tcgcaagaca gccaatgttg tcatgagtgt aggatttggg attccagcct
    19561 ttgcagtgga tactcatgtg gagcgtattt gcaaacacca cgatattgtc aaaaaatcag
    19621 cgacgccact tgaggtggaa aagcgggtca tggatatctt gccgcctgag cagtggttag
    19681 ctgcccatca ggccatgatt tattttggaa gagccatttg ccatccaaaa aatccagagt
    19741 gtgaccagta cccacaatta tatgatttta gcaatttgta agatgctaca ttgaaacttt
    19801 ttgcttgatt ttaagcatgc tttgtgctat agtaaatgat aactaaatat tcctttaaac
    19861 ctgtcccgtg aggcaggcaa ggagcgcgat aaagtagaag ggtgaagtct atactgtgtg
    19921 cagtagggct cgcttggcta taaatttcaa gtctccttgt ttaaggagac ttttcttttt
    19981 ggaggtttgt catgaaaaca aaagaagttg tagacgaatt gaccgtcaaa cgagcgatta
    20041 cgcgtattac ttatgagatt atcgaacgca acaaagattt gaataagatc gtcttggctg
    20101 gtattaaaac tcgtggtgtc tttattgccc accgaatcca agaacgtttg aagcagttag
    20161 aaaatctttc agttcctgtt gtggaattgg atactaaacc tttccgtgat gatgttaaaa
    20221 gtggagaaga tacttctttg gtttctgtcg atgtgacaga ccgcgaagtt atcttggtgg
    20281 atgatgtgct ctatacaggt cgtaccatcc gtgctgctat tgataatatt gtcggtcatg
    20341 gtcgtcctgc gcgtgtgagt ttagcagttc tagtcgatcg tggacataga gaattgccaa
    20401 tccgtccaga ttacgttgga aaaaatatcc caaccagtcg ttctgaagaa atcatcgtag
    20461 agatgacaga acttgatgac caagacagag ttctgattac tgaagaagct tagaaagtta
    20521 aaggagtagc catgtcagaa aatcaacaag cattgaacca tgtggtgtcc atggaagacc
    20581 tcactgttga tcaagtaatg aaattgatca agcgaggaat tgagtttaaa aatggagccc
    20641 agattcccta tgaagaccat ccgattgttt ccaatctctt ctttgaggat tctacacgga
    20701 cacataagtc ctttgaagtc gcagagatta aacttggatt ggaacgactt gactttgatg
    20761 tgaagactag ttcggttaat aagggtgaga cactttatga taccattttg actctgtctg
    20821 ctttaggagt ggatgtctgt gtgattcgcc atccagaggt cgactactat agagaattga
    20881 ttgctagtcc aacgattacg acttccatca tcaatggtgg agatggttcg ggccaacacc
    20941 ctagccagag cttgcttgat ttgatgacca tttatgagga atttggccac tttgagggtc
    21001 ttaaagttgc tattgcaggt gacttggacc actcacgcgt tgccaaatcc aatatgcaga
    21061 ttttgaaacg cttgggagct gaactctttt tcgctggacc tgaggaatgg agaagtcaag
    21121 agtttgcaga ctatggaaag tttgtaacca ttgatgaaat cattgatcag gttgatgtca
    21181 tgatgtttct ccgtgtgcaa cacgaacgcc atgatagtgg agctgtattt tcaaaagaag
    21241 actaccatgc ccaacatggc ttgactcaag aacgttacga tcgtttgaaa gaaacagcaa
    21301 tcctcatgca cccagctcca atcaatcgtg atgtagaaat agcagaccac ttggttgaag
    21361 caccaaaatc acggattgtc caacaaatga ccaatggtgt ctttgttcga atggcaatct
    21421 tagaatccgt actagcgagt agaaacgcca actaaaacac aagacgttaa aagacgccag
    21481 tgagcgtcca cgagaggtga aaatatgaca aaaagaattc tagtattaga agatggcaca
    21541 gtttttgaag gcaaggcctt cggagcagat attgatgtaa caggtgaaat cgtctttaat
    21601 acagggatga ccggctacca agaatccatt acagaccagt cttataatgg acaaatcttg
    21661 acctttactt atcctttggt aggaaattat ggtattaatc gtgatgatta tgaatccatt
    21721 attccaactt gtaagggagt cgttgttttt gaagaagcgc gtagagctag caactggcgc
    21781 aaccaaatga ccttggatga atttttgaaa gccaagaaaa ttccagggat ttcaggaatt
    21841 gatacgcgtg ctcttaccaa gattatccgt aagcatggta ctatgcgtgc aaccttgacc
    21901 catgttgggg acagtatgga ccatgtgacg gaccagctcc aagcaacagt tttaccgaca
    21961 gacaatatca aacaggtttc tactaaaacg tcttatccag ctccaggagt tggtttgagc
    22021 gtggtgctag tggactttgg tctcaagcac tcaatcctac gtgaactttc taaacgcaac
    22081 tgtaacgtga cagttgttcc ttattcgaca acggctgaag aaattctcca tctcaatcct
    22141 gacggagtta tgttgtcaaa tggtccaggt aacccagaag acgttccaca agcactcgac
    22201 atgattcgcg gtgtacaagg aaaaattcca atctttggta tttgtatggg acaccaactc
    22261 tttgcaatgg caaacggggc taagacctat aagatgaagt ttggccaccg tggattcaac
    22321 catgcggtac gtgaaatcgc aacaggacga gtagacttca ccagccagaa ccatggttat
    22381 gcagtcagcc gcgaggattt gccagagcac ttgattatta cccacgaaga aatcaatgac
    22441 aagtcagtgg aaggtgtgcg ccacagatac caacctgctt tctctgttca ataccaccca
    22501 gatgcagctc ctgggccaca cgacgctagc tacctatttg acgagtttat cgagatgatg
    22561 gaagttttta aacaatcaaa ctaagaacga gtaaaagctc gtcggagaat ttatgtaact
    22621 gaacacggac ggaaagctca gaatttagag aaaccaactt ggattgtcaa tccttccttg
    22681 atttcctaaa attcaatcgc tttctattcg tcctttgtat cttatttaat gtcgccctga
    22741 gaggctacga atagaaagga gaagggtgct ccgtatttgc tgaactgaat acgggctacg
    22801 gacggtgcta aaaagatagt tattcctaga actgacagtt cttcgtcata actcctattt
    22861 tagctttgtc cgcttgacgc ccttaatatc ttatatatgc ctaaacgtac tgatattcaa
    22921 aaaattatgg tgattggttc tggtcctatt attattggtc aggctgctga gtttgattac
    22981 gctgggaccc aggcttgctt gtcgttgaaa gaggaaggtt atgaggttgt tttggttaac
    23041 tcaaatcctg caaccatcat gacggacaag gaaattgctg ataaggttta cattgaaccg
    23101 attacacttg agtttgtgac acgtattctt cgtaaggaag gtccagatgc cttgctacca
    23161 acactcggtg gtcagacagg tctcaacatg gccatggaat tgtctaaaaa tggtatccta
    23221 gacgagcttg gcgttgaact tctgggtacc aaattatctg ccattgacca agcggaggac
    23281 cgtgacctct ttaaacaatt gatggaagag cttgagcaac ccattccaga atctgaaatt
    23341 gttaacacag tagaagaagc agttgccttt gcagcgacaa ttggctaccc agtcatcgtt
    23401 cgtccagcct ttacccttgg tggtactggt ggtggtatgt gtgccaacga aaaagaattg
    23461 cgtgaaatca ctgaaaatgg tttgaaattg tcacctgtta cccaatgttt gattgagcgt
    23521 tcgattgccg gtttcaagga aattgaatac gaagtgatgc gtgactcagc tgacaatgcc
    23581 ttggttgttt gtaacatgga aaactttgac ccagttggga ttcacacagg ggattccatt
    23641 gtatttgccc ctgcgcaaac catgtcagac tatgaaaacc aaatgcttcg tgatgcgagc
    23701 ttgagcatta ttcgtgccct caagattgaa ggtggatgta atgttcagct agctcttgat
    23761 cctaacagct tcaagtatta tgttatcgaa gtaaaccctc gtgtatcacg ttcgtcagcc
    23821 cttgcttcta aagcgacagg atatccgatt gctaagttgg ctgccaagat tgcagtaggt
    23881 ttgaccttgg atgaggttat aaacccagtt acaggttcaa cctatgccat gtttgaacca
    23941 gcccttgact acgtagttgc taagattcca cgtttcccat ttgacaagtt tgaaaagggt
    24001 gaacgccgtc tcggtacaca aatgaaggcg actggagaag tcatggcaat cggtcgtaac
    24061 atcgaggaat ctcttctcaa ggcctgccgc tcccttgaaa ttggggtgca ccacaatgaa
    24121 atacctgaac ttgcagcagt ttctgatgat gccttgattg aaaaggttgt caaagcccaa
    24181 gatgaccgtc tcttctacgt atcagaagcc attcgtcgtg gctacacacc tgaagaaatt
    24241 gcagagctta caaaaattga tatcttctat cttgataaac tcttgcatat ctttgaaatt
    24301 gagcaagaat tgggtgctca tccacaagat ctagaagttt tgaaaacagc caaacttaat
    24361 ggtttctcag accgtaagat tgctgaactc tggggaacga ctgatgatca agttcgccaa
    24421 cttcgcttgg aaaacaagat tgttccagtt tataagatgg tagatacttg tgcggcagag
    24481 ttcgactctg aaacgccata tttctattca acctatggtt gggaaaatga atctatcaga
    24541 tctgataaag aatctgtact tgtcctaggt tcaggtccaa tccgtatcgg tcaaggggtt
    24601 gagtttgact acgcaaccgt tcactctgtt aaggctatcc aggcagctgg ttatgaagct
    24661 atcatcatga actcaaaccc agagaccgtt tcaacagatt tctctgtatc agataagctt
    24721 tactttgagc cattgacatt cgaagatgtt atgaacgtca ttgacttgga acaaccaaag
    24781 ggagttatcg ttcagtttgg tggtcaaaca gccatcaacc ttgcggagcc attggcaaaa
    24841 gcaggtgtga ccatccttgg tacacaggtt gctgacctag atcgtgccga agaccgtgac
    24901 ctcttcgagc aagctctcaa agaattggat attccacagc caccaggaca aacggctacc
    24961 aatgaagaag aagcagctct tgcagctcgt aagattggct tcccagttct tgtccgccca
    25021 tcttatgtac ttggtggacg tgccatggaa atcgttgaaa acgaagaaga ccttcgttct
    25081 tacatgcgaa ctgctgttaa ggctagtcca gatcacccag ttcttgtcga ctcttatatc
    25141 gttgggcaag agtgcgaagt tgatgccatt tcagatggta aagatgtact cattcctggt
    25201 atcatggagc atatcgaacg tgctggtgtc cactcaggtg actcaatggc tgtttaccca
    25261 ccacaaacct tgtcgcaaaa ggttcaggag accatcgcag actacaccaa acgcttagca
    25321 atcggtcttc actgccttgg aatgatgaac atccagtttg ttatcaagga tgaaaaagtc
    25381 tacgttattg aggtcaatcc acgtgccagc cgtaccgttc cattcctatc taaggtaacc
    25441 aatattccta tggctcaagt agcgaccaaa ctcattcttg gtcaaagttt atcagaactt
    25501 ggctaccaaa atggacttta ccctgaaagc acccgtgttc atatcaaggc acctgtcttc
    25561 tcctttacca aactagctaa ggtagacagc ttgctcggtc ctgaaatgaa gtcaacaggt
    25621 gaagttatgg gttctgatgc tactttggaa aaagctctct ataaagcctt tgaagcttct
    25681 tatctacact tgccaacttt tggtaatgtc gtctttacca tcgctgatga tgccaaagaa
    25741 gaagccttga acttggctcg tcgtttccaa aacattggtt atggaatcct tgcgacagaa
    25801 gggacagcag ccttctttgc tagtcatggc ttgcaagccc aacctgttgg taagattggt
    25861 gatgacgata aggatatccc aagttttgta cgcaaaggaa gaattcaagc tatcattaac
    25921 acagtaggaa caaaacgaac tgctgacgaa gatggtgagc aaattcgtcg ttcagccatt
    25981 gaacacgggg tgcccctctt cacagcgcta gatacagcta atgccatgct taaggtactt
    26041 gaaagtcgta gctttgttac agaagcgatt taaatagaaa aaataagata tagcagactg
    26101 aatttagaac agtacacagg gatactaaaa tatttctaga aattaatttg aattttctaa
    26161 ttgatttgtt cgcatcttat ttcaatctac tatagaaaaa agtctttaaa attataaaac
    26221 gcatcatatc aaggtttttc aaaaaacttg atatgatgcg ttttattgtg ggaatatgta
    26281 tttcattttc tactaaaatt atgtttttga ataacctcta tcttagtagt ctgtataatc
    26341 cccctcaatc agtttttgcg ataagcttta atgctatgac tataccactc ttgcatttct
    26401 tttgatggtg gtgtcatata atcgccatac atctgggtta aaaattggtc atattttttg
    26461 ggaacaggca acatacggcc ctcaaactca gttaaaatca gttctttaaa ggtatcaact
    26521 gggaagattt ctttcatccc ttccttaccg atcccaactc ctccttcata ttgaggagtg
    26581 ttggttacag catttttgac tagttgatca attttcttgt aaaagtagcg aggattgaca
    26641 aatcggagag cgtaccagct acataatcta agaaaatctt ttagtttgct atcaccgtga
    26701 actgctcgtg attttttgat ataagctagt tgacgaagag ccacatactt atagctcttg
    26761 tcgacaatgc tcaagtctgt aaatcgatca attgggaaga catcgatgaa aaggctggta
    26821 tcatgacgct tgtacttaac atggtcttct ataacagtag aagtgtccaa aatcgatgcg
    26881 aaattatgga agtaccaaga agatgtatcg taggaaagaa ccttgtagcg agggtgattt
    26941 tcttcttcaa taatcttcag taaacgctca taatcctcac gataaaggga aatatcaata
    27001 tcatcatccc aaggaatcat acctttgtgg cggatggctc caagcatggt tccataactg
    27061 agaaaataag gaatatcatg tttcttacaa gtctcatcaa tatagtccag cagggctagt
    27121 tgaatttctt taatttcttt tttttctaaa tattgcatcc taatcctcca atttataagc
    27181 gtgaaattca tgactgtaga agcgtttttc ttctggtggc agggtcatat aatctccata
    27241 aaattgtgtc aaaatagtat caaatttttc aggtgcagga aggcttaaat tctcaaaggg
    27301 taaatcgatt gttttatcaa aggtaccact tgggaagact tccttttcct taaattttga
    27361 aggaataaaa gccatatact gcccattttc acgactatat ttttgaattt ctttctcgat
    27421 tttatttgca aaataacgag gagaaaccgg tcgaaggagc aaccaaaagg ctgttcgtat
    27481 ccaatctttt aaaaggctat ccttatagac aatattttta tgtttactga aagacagcag
    27541 tttgaagctt tccagtttat aacaagtatc aatgacctta ggatcatcaa agcgatctat
    27601 agggaaaata tcgataaaga taccagactc ataggttttt gtatttcgag tatcaataat
    27661 tttagtcgta ctgtcggtta tcttgataaa gttgttaaag tagttcttat cagtttctaa
    27721 ggataggagc ttatacttgc ttttttcctt ttgaaaaatg ttaataaatc gttggtagtc
    27781 ttctctaggc atggacagat caatatcgtc gtcccaaggg ataaagccct catgtcgaac
    27841 cgccccaatc agagtaccgt agttaataat atagttgata ttgtgctttt tacagagagt
    27901 atcaatataa tccaaaattt ctaattcaat ttgtttggca tcttcaatgg ttagttgttt
    27961 cattttaaac tcctatgatt ttttgaattt attttttaag gctaggacat ggtttaaaaa
    28021 ttcatagaaa atgctatctt ttgtgaagac aagtagacta atataagaga tagctgataa
    28081 caagacaatc aaaccagtat taatcaaaaa tggcaaatta atgaccatat ccacaggata
    28141 cacgaaatta atcaggaaat aaattcccac aaaggaaagt gaaaagagcg agtatcgaac
    28201 agtatagcta aagatatgtc ccaagtggat gagttgtttt ctatggatga aaatgatata
    28261 gaaaacaagt agagaagtct ctgataacat agttgtcagt aagtagtatt caggagccac
    28321 gatatggttg aaaaagagga gactattcaa gcccaaattg agtagcccag caaagactgt
    28381 atagactgtg atacgttttt catagccatt ggtaaagaga atttgggaac caagaatggt
    28441 atctaaggcc aggataatcg tacgaaaagc gaagagagag gtcaagatgc cgcctccgat
    28501 atatttttca ctaccgtaaa gtaggatggc atttggtcct aaaaccatga gtccaaaact
    28561 cagtggaatg ataaagaagt taaagattcg actacctcta ttaaccagag aaacataggc
    28621 ttctttgtct cctttcccca gatagtaact gagacgaggc acactcactc caattgcacc
    28681 tgttacaacc ccagctataa cggtcacaat tcgctgagct atggtatagt aactaacgtt
    28741 gacatcaatc cctgttttaa cgaggaagag gcgatctaaa aaagtgaaga gcatattggc
    28801 attggcaaag actaacatgg ctgtcagagg gagaaagagt ggtttaaaat cacttaggtg
    28861 aatcttaaca agtttgatgt ctcttttaat ccaaaaataa ctaatcaggt agttaatcag
    28921 cgtcgataaa ctcatcacaa gtgtatagac aacaatatcg tgttcatttt taacaaataa
    28981 gaaaatagag accagcatca ggatacggat gaaggcagtt ttgtaaaaga gaaaactgta
    29041 attttccaga gcttcattga cccattcaat tgaaaaaatc tgggcaatga gttgaatccc
    29101 cataacaagg tagacctttt tgacgattgg attatcaata aagaagagag gataggctag
    29161 gatatagaca gcagtggtca aaatcgtaca agcgatgcac aaataaaaaa gactagaaaa
    29221 ggttctgtta agatcttttt tgttatcctt gacattactg atagccctta aaccgtagtt
    29281 atagacacca taagttgcaa agggcaagaa aaatgacaaa atagtgtcga ctgagttgaa
    29341 gtaaccatag tcagttcggt ccaagacacg cgcgacatag gttccagtta ggatgggaaa
    29401 aataatattc aagacacgaa ttcccatgta agatagagca tttaatttta tacttttcat
    29461 tcaatttacc tcgtttttca ttatatcata aagttagcta ataagaaatg aagggcagta
    29521 agtcaagtaa tcactttgaa gtttcaaatt ttaaatttta agttttcttt aaggaaagta
    29581 tattattctg aaggactcta aaatttcgca gccatttatt agtaattgct acagaattcc
    29641 tagtcattac tagaaatgga ctagtttctt tgaataatag aactgcataa ttctcctatt
    29701 ctagaagggg aggaccagta tttcttttat gataggacta gattgtggta taatagagag
    29761 aataagtttt tttagtaaga caaaggagaa aatagatgat ttatgcagga attcttgccg
    29821 gtggaactgg cacacgcatg ggaatcagta acttgccaaa acaattttta gagctaggtg
    29881 atcgacctat tttgattcat acaattgaaa aatttgtctt ggagccaagt attgaaaaaa
    29941 ttgtagttgg tgttcatgga gactgggttt ctcatgcaga agatcttgta gataaatatc
    30001 ttcctcttta taaggaacgt atcatcatta caaagggtgg tgctgaccgc aatacaagta
    30061 ttaagaaaat cattgaagcc attgatgctt atcgtccgct tactccagag gatatcgttg
    30121 ttacccacga ttctgttcgt ccatttatta cacttcgcat gattcaggac aatatccaac
    30181 ttgcccaaaa tcatgacgca gtggacacag tggtagaagc ggttgatact atcgttgaaa
    30241 gtaccaatgg tcaatttatt acagatattc caaatcgtgc tcacctttat caaggacaaa
    30301 cacctcaaac attccgttgc aaggacttca tggaccttta tggatctctt tctgatgaag
    30361 agaaggaaat cttgacagat gcatgtaaaa tctttgtgat caaaggaaaa gatgtggcct
    30421 tggccaaagg tgaatactca aatctgaaga ttacaaccgt aacagatttg aagattgcaa
    30481 aaagtatgat tgagaaagac tagtaaaatg attaatcaaa tttatcaact aactaagcct
    30541 aagtttatca atgtcaaata tcaggaagag gctattgacc aagagaatca tatccttatc
    30601 cgtcccaact acatggctgt ctgtcatgcg gatcagcgtt actatcaggg aaaacgtgat
    30661 cccaagattt tgaataaaaa gcttccaatg gcaatgattc acgagtcatg tggaaccgtc
    30721 atttctgacc cgaccggaac ctacgaagtt ggtcaaaaag ttgtcatgat tcccaatcag
    30781 tctcctatgc agagtgatga agaattctat gaaaactaca tgacagggac ccatttcttg
    30841 tctagtggat ttgatggctt tatgagagag tttgtttctc tccctaaaga tcgtgtggtg
    30901 gcttatgatg ctattgaaga tacggttgca gccattacag agtttgtcag tgtgggcatg
    30961 cacgctatga atcgtctatt gactcttgct catagcaagc gggagcggat tgccgttatt
    31021 ggagatggaa gtttagcttt tgtggttgcc aatattatca actatacttt gccagaatca
    31081 gagattgtgg ttattggtcg tcattgggaa aagttggaac tcttctcatt tgccaaagaa
    31141 tgctatatta cggataatat tcctgaagat ttggcctttg accatgcttt tgaatgttgt
    31201 ggtggtgatg gtactggacc agctattaat gacttgattc actacattcg tcctcaggga
    31261 acgattctca tgatgggagt tagcgaatat aaagtcaatc tcaatactcg cgatgcctta
    31321 gaaaagggct tgattttggt tgggtcatct cgttctggtc gcattgattt tgaaaatgct
    31381 atccaaatga tggaagtcaa gaaatttgcc aatcgtctta aaaatatcct ttatctagaa
    31441 gaacctgtaa gagaaattaa agatattcac cgtgtctttg caaccgattt aaacacagcc
    31501 tttaaaacag tgtttaagtg ggaagtataa gtactggagg ttaattgtgg agaaaatcat
    31561 taaagaaaaa atttcttcct tacttagtca agaagaggaa gtcctcagtg ttgaacaact
    31621 gggtggaatg accaatcaaa actatttggc caaaacaaca aataagcaat acattgttaa
    31681 attctttggt aaaggaacag aaaagcttat caatcgacaa gatgaaaagt acaatcttga
    31741 actactaaag gatttaggct tagatgtaaa aaattatctt tttgatattg aagctggtat
    31801 caaagtaaat gagtatatcg aatctgcgat tacgcttgat tcaacgtcaa tcaagaccaa
    31861 gttcgacaaa attgctccaa tattacaaac tattcataca tctgctaagg aattaagagg
    31921 agaatttgct ccttttgaag aaatcaaaaa atacgaatcc ttgattgaag aacaaattcc
    31981 ttatgccaac tatgaatctg ttagaaatgc agtcttctcc ttagagaaaa gactggctga
    32041 cttaggtgtt gacagaaaat cttgtcatat cgatttggtg cctgaaaact ttatcgaatc
    32101 acctcaagga cgactttatt tgattgactg ggaatattca tcaatgaatg atccaatgtg
    32161 ggatttggct gccctctttt tagagtctga attcacttcc caagaggaag aaactttctt
    32221 atctcactat gagagtgacc aaacaccggt ttctcatgaa aagattgcta tttataaaat
    32281 tttacaagat actatttgga gtctatggac tgtatataag gaagagcaag gtgcagattt
    32341 tggttactat ggtgtgaatc gttaccaaag agctgttaaa ggtttggctt cttatggagg
    32401 ttcagatgaa aagtaaaaac ggagttcctt ttggccttct ctcaggtatt ttctggggct
    32461 tgggtctaac ggttagtgct tatatctttt cgatttttac agatttgtca ccctttgtgg
    32521 tggctgcaac tcatgatttt ttgagcatct ttatcttact agcttttctc ttggtaaaag
    32581 aagggaaagt tcgcctctca attttcttaa atattcgcaa tgtcagtgtt atcatcggag
    32641 ccttgctagc aggccctatc ggtatgcagg ccaatcttta tgcagttaag tatatcggaa
    32701 gttctttagt ttcatctgta tcggctattt accctgcgat ttcagttcta ttggctttct
    32761 tctttttgaa gcacaagatt tcgaaaaata ctgtatttgg gattgtcttg attattggag
    32821 ggattattgc ccagacctat aaggttgaac aggttaattc tttctacatt gggattcttt
    32881 gtgctttggt ttgtgctatt gcatggggaa gtgagagtgt tcttagctct tttgccatgg
    32941 aaagtgaatt gagtgaaatc gaagccctct taatccgtca agtaacttcg ttcttgtcct
    33001 atcttgtgat tgtgctcttc tctcatcagt catttgttgc agtagccaat ggacaattgc
    33061 taggtctcat gattgtcttt gtagcctttg atatgatttc ctatttggct tattatatcg
    33121 ctatcaatcg cttgcaacca gccaaggcta caggcttgaa cgtgagctat gtagtatgga
    33181 ctgtcttgtt cgcagctctt ttcttgggaa catcattaga tatgctgacc attatgacgt
    33241 cacttgtcgt cattgctgga gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa
    33301 agccattatc ttagcagcgg gattgggaac tcgcttgcgt cctatgactg aaaatacccc
    33361 taaagccttg gttcaggtta atcaaaaacc tttgattgaa taccaaattg agtttctcaa
    33421 agaaaaagga atcaatgaca tcatcatcat cgttggttat cttaaagaac aattcgatta
    33481 tttaaaagaa aaatacggtg ttcgcctcgt tttcaatgat aaatacgctg actacaataa
    33541 cttttactct ctctatcttg taaaagaaga attggccaac agctatgtta ttgatgctga
    33601 caattatctc tttaaaaata tgttccgcaa tgatttgaca cgttcgactt attttagtgt
    33661 ttatcgtgaa gattgtacca acgaatggtt cttggtctat ggagatgact acaaggttca
    33721 agacattatt gttgatagca aggcaggtcg catccttagt ggtgtatcct tctgggatgc
    33781 tccaactgca gaaaagattg tcagctttat cgacaaggct tatgcaagtg gtgaatttgt
    33841 tgatctctat tgggacaata tggttaagga taatatcaaa gagctagatg tctatgttga
    33901 agaattagaa ggcaatagca tttatgagat cgatagtgtc caagactatc gtaaattaga
    33961 agaaattctt aaaaacgaaa attaaagatt ccaacatctg acaaaatagt cggatgtttt
    34021 ttgatttttt acgaactttt acgaatagat agatgagtag aaaaagaaat ggagttattt
    34081 atgaaaatca caaactatga aatctataag ttaaaaaaat caggtttgac caatcaacag
    34141 attttgaaag tgctagaata cggtgaaaat gttgatcagg agcttttgtt gggtgatatt
    34201 gcagatatct caggttgccg taatccagcc gtttttatgg aacgttattt tcagatagac
    34261 gatgcgcatt tgtcgaaaga gtttcaaaaa tttccatctt tctctatttt agatgactgt
    34321 tatccttggg atttgagtga aatatatgat gcgcctgtac ttttatttta caagggaaat
    34381 cttgacctcc tgaaattccc gaaggtagcg gtcgtgggca gtcgtgcttg tagcaaacag
    34441 ggagctaagt cagttgaaaa agtcattcaa ggcttggaaa atgaactggt tattgtcagt
    34501 ggtctggcca agggcattga cacagcagct catatggcag ctcttcagaa tggcggaaaa
    34561 accattgcag tgattggaac aggactggat gtgttttatc ctaaagccaa caaacgcttg
    34621 caagactaca tcggcaatga ccatctggct ctaagtgaat atggacctgg agaacaacct
    34681 ctgaaatttc attttcctgc ccgtaatcgc atcattgctg gactttgtcg tggtgtgatt
    34741 gtagcagagg ctaagatgcg ttcaggtagt ctcattacct gtgagcgagc aatggaagaa
    34801 ggacgcgatg tctttgctat tcctggtagc attttagatg gactatcaga cggttgccat
    34861 catttgattc aagaaggagc aaaattggtc accagtgggc aagatgttct tgcggaattt
    34921 gaattttaaa aatgacctaa gctagaattc taagaaaaaa tcaattttaa gagaaaatga
    34981 acccaacatt tccataataa aacgcatatt agcaagtttt taacacttga taatatgcgt
    35041 tttttctaag tggattagta gagtagagga ttttttcata taatactctt cgaaaatctc
    35101 ttcaaactac gtcagcttcc atctgcaacc tcaaaacagt attttgagct gacttcgtca
    35161 gtcttatcta caacctcaaa gcagtgcttt gagcaacctg tggctagctt cctagtttgc
    35221 gctttgattt tcattgagta taagggaaag tatagtgaat tgaaataaga tgtgaacaac
    35281 tctatcagga aagtcaaatt aatttataga aatattttag cagccaaggt gcactgttat
    35341 agattcaata cactataatt tagtgtaatt gagaaaggag aaatgattgt gattgatgtt
    35401 ggctaggtta ttttcaatga ttcctaccgt ctcaaatctt gtcagtaagg aaaaataaat
    35461 tcttcaaaag tagagattac aaggcttgtt taagaaagaa ttcaaagacc ttgacaaata
    35521 aaaataaaat ggttattata agaaatggtc taaaatagat gatgatactt ttcgaaaatc
    35581 tttttacgtc agctcagctt tgccttgctg tgttttgagc aagctacggt tagcttccga
    35641 gtttgatttt catttactag aaatgaaact gatgagagat atcagtagac atttgagtca
    35701 ggatattatg gaaaatgata aaaagagctc gtgagattgg catatcagac tactaaagta
    35761 ttgagtttgt taggatttta gcgactagtt agctgggaaa ggaagatatt gtgacaaata
    35821 ataaactgta ttcgttgata gaatttagaa ataaaatata tgaagaatta gaactttcca
    35881 gaagtgattt agcgatttta ctatgtgcca tgcttatcgc ctctatcgga ttaaatatgg
    35941 attcgactcc cgtgattatt ggagccatgt taatctctcc tttgatgaca cctattctgg
    36001 gagtggggct ctctctagct atatttgatt ttaaattgtt aagaaaatct tttaaaatat
    36061 tagctattca aattcttgcc agtttaatag cttcaacact ttatttttat ctttctccca
    36121 tttcgtatgc tagttcggaa attgttgcta gaacctctcc gactatttgg gatgttctca
    36181 ttgcttttgt aggaggtata gcaggtatta ttggtgctag gaaaaaagag accaataata
    36241 ttgttcctgg tgttgctatt gcaaccgcct tgatgcctcc tctttgtaca gtaggttatg
    36301 ctattgcttc tgctaatcta aaatttatca taggctcctc ttacctattc ctcatcaatt
    36361 gtagctttat tgtcattgcg acttatatag gtgttaggtt gatgatggtt aagaaacatt
    36421 attttaaaga taatgaagaa gactctaaaa tgcgtaggat tttgcttcta gttgctgttt
    36481 tgctgatgat tccgagtttc atctctgcaa cgactttagt gagagaaacg ttgaaaaaag
    36541 agtcccttaa gaaatttata tcagagcagt ttcaggggca taatattttg aaaaaaacct
    36601 attctaaaaa gactcatacc ctaaagctaa ccatttcagg aaattatttg acagaagaag
    36661 aactcgatat gatttcaagt aagagaggtg actatggttt aagtgatgtt tctgttcaag
    36721 tttcacaatt gtctgattca gaacaactta gtaaggaaga actggtggag tatttcttcc
    36781 agtatatcaa ggataaggaa gcaaaagaaa aggaaaaagc taataagttt tatacagagt
    36841 ctgaggagca ataatttctt gagaatagct ggtttttctc gtgagtcttc tatgtatatc
    36901 aaaggaagac tgaggtttta agtataaaac ttttcttcta ttatagtagc taagtcttga
    36961 cagggttcaa aaaatggttt acactttata aagtttatta ctttgaaaag gtgtgatact
    37021 gtggctacgg caacaaaaaa gaaaaaatca acagttaaaa aaaatctagt catcgtggag
    37081 tcgcctgcta aggccaagac gattgaaaaa tatctaggca gaaactacaa ggttttagcc
    37141 agtgtcgggc atatccgtga tttgaagaaa tccagtatgt ccgtcgatat tgaaaataat
    37201 tatgaaccgc aatatatcaa tatccgagga aaaggccctc ttatcaatga cttgaaaaaa
    37261 gaagctaaaa aagctaataa agtttttctc gcgagtgacc cggaccgtga aggagaagcg
    37321 atttcttggc atttggccca tattctcaac ttggatgaaa atgatgccaa ccgtgtggtc
    37381 ttcaatgaaa tcaccaagga tgcagtcaaa aatgctttta aagaacctcg taagatcgat
    37441 atggacttgg tcgatgccca acaagctcgt cggatcttgg atcgcttggt agggtattcg
    37501 atttcgccta ttttgtggaa gaaggtcaag aagggcttgt cagcaggtcg cgttcagtcc
    37561 attgccctta aactcatcat tgaccgtgaa aatgaaatca atgccttcca gccagaagaa
    37621 tactggacag ttgatgctgt ctttaaaaag ggaaccaaac aatttcatgc ttccttctat
    37681 ggagtagatg gtaaaaagat gaaactgacc agcaatgacg aagtcaagga agtcttgtct
    37741 cgtctgacga gtaaagactt ttcagtagat caggtggata agaaagagcg caagcgcaat
    37801 gctcctttac cctataccac ttcatctatg cagatggatg ctgccaataa aatcaatttc
    37861 cgtactcgaa aaaccatgat ggttgcccaa cagctctatg aaggaattaa tatcggttct
    37921 ggtgttcaag gtttgattac ctatatgcgt accgattcga ctcgtatcag tcctgtagcg
    37981 caaaatgagg cggcaagctt cattacggat cgttttggta gtaagtattc taagcacggt
    38041 agcaaggtca aaaacgcatc aggtgctcag gatgcccatg aggctattcg tccgtcaagt
    38101 gtctttaata caccagaaag catcgctaag tatctggaca aggatcagct caagctatat
    38161 acccttatct ggaatcgttt tgtggctagc cagatgacag cggccgtttt tgataccatg
    38221 gctgttaaat tgtctcaaaa aggggttcaa tttgctgcca atggtagtca ggttaagttt
    38281 gatggttatc ttaccattta taatgattct gacaagaata agatgttacc ggacatggtt
    38341 gttggagatg tggtcaaaca ggtcaatagc aaaccagagc aacatttcac ccaaccgcct
    38401 gcccgttatt ctgaagcaac actgattaaa accttagagg aaaatggggt tggacgtcca
    38461 tcaacctacg cgccaaccat tgaaaccatt cagaaacgtt attatgttcg cctggcagcc
    38521 aaacgttttg aaccgacaga gttgggagaa attgtcaata agctcatcgt tgaatatttc
    38581 ccagatatcg taaacgtgac cttcacagct gaaatggaag gtaaactgga tgatgtcgaa
    38641 gttggaaaag agcagtggcg acgggtcatt gatgcctttt acaaaccatt ctctaaagaa
    38701 gttgccaagg ctgaagaaga aatggaaaaa atccagatta aggatgaacc agctggattt
    38761 gactgtgaag tgtgtggcag tccaatggtc attaaacttg gtcgttttgg taaattctac
    38821 gcttgtagca atttcccaga ttgccgtcat acccaagcaa tcgtgaaaga gattggtgtt
    38881 gagtgtccaa gctgtcatca gggacaaatt attgagcgaa aaaccaagcg taatcgccta
    38941 ttctatggtt gcaatcgcta tccagaatgt gaatttacct cttgggacaa gcctgttggt
    39001 cgtgactgtc caaaatgtgg caacttcctc atggagaaaa aagtccgtgg tggtggcaag
    39061 caggttgttt gtagcaaagg cgactacgag gaagaaaaga ttaaataaga ggaggggccc
    39121 gaaagtaaat ttcaggctcc ttttggttag aacttgacaa aatacatcat tttatgcgaa
    39181 actagaagaa gattatttta actaggagaa gttatgcgtc ttatctatct gataattggt
    39241 tttttatcac tggccttggc tattgttggg gttgttttac ccttgttgcc gacaacgcct
    39301 ttccttttgt tgtctattgc ttgtttctcc agaagttcca agcgtttcga agactggctt
    39361 tatcatacca agctctatca aacatatgta gctgattttc gcgagactaa gtctattacg
    39421 cgtgaacgaa agaaaaaaat catcgtctct atctacgtct tgatgggaat ttctatttat
    39481 tttgcacctc ttttaccagt caaaattggt ctgggtgctt tgaccatctt tatcacttat
    39541 tatctcttca aggtcattcc agacaaagaa taattaaaag agtagttatt tcccttgata
    39601 aaattgaaag catattcata acaatatgat ataataaatt tgaagtaata ttcaaggaga
    39661 atcaaatgat ttacgaattt tgtgctgaaa atgtgacttt acttgaaaaa gcgatgcagg
    39721 ctggagctcg tcggattgaa ctctgtgata atctagcagt tggtgggaca acacccagct
    39781 atggagtgac taaggcagcg gttgaactgg cagctaacta cgatacaacc atcatgacca
    39841 tgattcggcc acgtggtggt gactttgtct ataatgacct agaaattgct atcatgctag
    39901 aagacattcg tttgactgct caggctggaa gtcaaggggt tgtatttgga gctttaactg
    39961 ctgataaaaa gttggataag cctaatctgg aaaagttaat tgctgcatca aaaggaatgg
    40021 aaattgtctt tcacatggcc tttgatgaac taagtgatga agatcaaccg gaagctattg
    40081 actggctcag tcaagccggt gtcactcgta tcctaactcg tgctggtgtg tctggcgact
    40141 ccttagaaaa acgttttgtt cactatcaca gaattttgga gtacgctaaa ggtaaaattg
    40201 aaattctacc aggtgggggg attgaccttg aaaaccgtca aacctttatc gaccaggtgg
    40261 gggtaacaca attgcatggt actaaggttg ttttttaaaa aatagaaagg aactgctagc
    40321 tttgggtagc agttttcact tatgtttgaa atttttaaat cctatcaatt taatcaagaa
    40381 aaggctcatg attatggttt tatagaaaat agcgaagtct ggacatatag ttgccagatt
    40441 ttgcaaggtg actttgtcat gactgtgtcc atcactgctg ataatgtgaa ctttcaagtc
    40501 tttgaccaag aaactggtga cctctatcct cacgttcata tggaaagcat gaggggaagt
    40561 tttgtcggaa atgtccgtga ggcttgtctg gagattcttt accagattcg gaaggcttgt
    40621 tttgatgtgc aagattttat ctgtcatcag actaagcgta tcatgactca agttcaggaa
    40681 aagtatggaa accagttgga gtatctgtgg gaaaaatcgc ctgatacagc tgtattgcgc
    40741 catgaaggca atcaaaagtg gtatgccgtc ttgatgaaaa tctcttggaa taagctggaa
    40801 aagggcagag aaggacaagt ggaagcagtc aacctcaagc atgaccaagt agctaatttg
    40861 ctttcacaaa aggggattta tccagccttc catatgagca agcgctactg gattagtgtg
    40921 tcccttgatg atactttatc agatgaagaa gtactggaat tgatagaaaa aagttggaac
    40981 ttaacctcta aaaaatgaat attttaataa ttttcatgaa ctttcaatta gctaaacatt
    41041 ctttactgaa gaaattttca gaaaatatag aatttaccac accagaggaa tatggtgcca
    41101 tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctat tcgcctcact
    41161 gtcatgatga ccttcggaat ggcagtggca aatagccttg ctgctgtcaa gaatggtgca
    41221 ggacgtgttg aagggactat caatggtatt agggagcgag ctggaaatgc tgctttggaa
    41281 gaaattgcag tggctctcaa tattcgccaa gattactacc aagtagaaac cagtattgtc
    41341 ctaaatgaga ccatcaatac gtcagaaatg gtttctcgct tctctggtat tccagttcct
    41401 aaaaacaaag ccgtcgttgg tggcaatacc ttctcccacg aatctggtat tcaccaagat
    41461 ggaatcctta aaaatcctct cacttatgag aacatcacac ctgaattggt tggtgttaag
    41521 attccgcttg taaaattatc tggtcgccat gcttttgttg agaaactgag agaattggcc
    41581 ctagatttta cagaagagga tatcaaacca ctctttgcta agttcaaggc actggtcgat
    41641 aagaagtaag aaatcacaga tgcagatatt cgatctttgg tagctggaac catggttgaa
    41701 aatccagaag gcttccactt tgatgattta caacttcaaa ctcatgcaga taatgacatt
    41761 gaagcgctcg ttagcctagc caatatggat ggtgagaaag tcgaatttaa tgcgacaggg
    41821 caaggttccg ttgaagcaat ctttaacgct atcgataagt tctttaatta atctgttcgt
    41881 ttggtgtcct acactatcaa tgcggtaaca gatggaatcg atgcccagga tcgggttttg
    41941 gtcactgttg aaaacagaga tacagaaacc atctttaatg cagcagggct tgattttgat
    42001 gtgttgaagg cttctgctat tgcctatata aacgctaata cctttgttca aaaagagaat
    42061 gcaggtgaga tgggacgcag tgtttcttac cacgatatgc ctagtgtgta aaggagaagg
    42121 ctatgacaaa gaaaatagta gctctagcag gagatggaat tggcccagaa atcatggagg
    42181 ctggtttaga agttctggag gctctagcta aaaaaacagg ctttgtctat gaaatagaca
    42241 gacgaccttt tggaggtgca ggtattgatg ctgcagggca ccccttacct gatgaaaccc
    42301 tcaaggcatg tagagaagca gatgccattc tcctagcggc tatcggtagt ccccagtatg
    42361 atggggcagt ggttcggcct gaacaaggac ttctggctct ccgtaaggaa ctcaatctct
    42421 atgccaatat tcgcccggtt aagatttttg agagtctcaa gcatttgtca ccactaaaat
    42481 cagaacgaat tgctggggtt gactttgtcg ttgtgcggga gttgacaggc gggatttact
    42541 ttggggatca tatccttgaa gaaagaaaag cgcgtgatat caacgactat agctacgagg
    42601 aagtggagcg gattattcgc aaggcctttg aaatcgcaag aaatcggaga aaaatcgtta
    42661 ctagtatcga taagcaaaat gtgttggcaa catcaaaact ctggcggaaa gtagctgagg
    42721 aagtcgcgca ggatttccca gatgtaacct tggagcacca gctagtcgac tcagcttcca
    42781 tgcttatgat taccaatcct gctaaatttg atgtcattgt gacagaaaat cttttcggag
    42841 atattctctc ggatgaatca agcgttttat ctggcacact tggggttatg ccatcagcca
    42901 gtcattctga aaagggtcca agtctctatg agcccattca cggttcagcg cctgatattg
    42961 caggtcaagg aattgctaat cctatctcca tgattttatc agttgccatg atgttgagag
    43021 atagttttgg acgttatgag gatgcagagc gtatcgagca tgctgttgag gcaagtttgg
    43081 cagctggtgt tttaacaaga gatataggtg gacagacttc gaccaaggaa atgacggaag
    43141 ctattattgc aaggttatga agttagacga aaaaattact ctagccctct tgatttggaa
    43201 tgtcatgatt ttcttgattt atggtattga caaatctaag gcaaggagaa gagtttggcg
    43261 catccctgag aaaatcttac ttattttagc ctttacttgt ggtggttttg gtgcctggct
    43321 agcaggaatc atctttcacc acaagactcg aaaatggtac tttaaaatag tttggtttct
    43381 tgggatggtg accacactag tagccttata ttttatttgg aggtaatgga tggcagggtc
    43441 ttcgagtgaa cacgctgctt gggctctagc ggactatggt tttaaggtcg tgattgcagg
    43501 atctttcggt gacattcatt acaataatga actcaataat ggcatgttgc caatcgttca
    43561 acctagagag gttagagaga aactagccca gctaaaacca accgaccagg taactgtgga
    43621 cttggaacaa caaaaaatca tctcaccagt tgaagaattc accttcgaga tagatagcga
    43681 gtggaaacat aaactcctaa atagtttgga tgatatcggt attaccttgc agtatgaaga
    43741 gttgattgct gcttatgaaa aacaacgacc agcctactgg caggattaga aaaaatagaa
    43801 aaggaaatat agtaaactga aataagatgt aaacaaatga attagagctt aacatccatt
    43861 tccagcaatt ttttagaaac tacagtggac tattctggat tcaacacatt ataaaattat
    43921 gacaaaacac attcacaaga aggctacgac attttaaaag gtgagggcgg atgtatcgtt
    43981 tgccctacta aagttggtta cattatcatg accagtgaca aggcaggact tgagcgtaag
    44041 ttcgcagcca aagaacgtaa gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat
    44101 gaacttcgcg ctttagcgca actcaaccca gaaattgaag cattctacta aaaacattgg
    44161 gatgaagata ttcttcttgg ttgtatcctt ccttggaaac cagaagcctc tgaaaaactc
    44221 aaagcatacg gggatggccg tgaagaactt atgactgatg tacgtggtac tagctgtttt
    44281 gttatcaagt ttggaaaagc aggtgaacaa ttggctgcca agctttggga agaaggtaaa
    44341 atggtctacg cctcatctgc ttcaatgaca aaacgattga aactcgctat gagagcaagg
    44401 tgtaatggtg tctatggtcg ataaggacgg caaactcatc ccagaacaag gaggagcacg
    44461 ttcaacctca ccagcaccag ttgtgatccg taaagggctt gacattgata tagtaaaatg
    44521 aagtaagagc aggacaaatt aatcaggaca gtcaaatcga tttctaacaa tgttttagaa
    44581 gtagaggtgt actattctag tttcaatcca ctataaaatc atgatgcacc tgtcagatac
    44641 ttttaactca tgggactgcc gtcagggtgg gtattattaa gataaaaaaa gaagtctagt
    44701 gttatgagat attaaagctc ctaacactgg gcttttgttt agaatttctt ttctttttct
    44761 atagaatatg gtattctatg tagaaaatat atgttaataa gtaatgccaa tatttaaaca
    44821 tcattagtaa aaggagttag attgatgaat aaaagaaaag ttagtttaga agatttttat
    44881 aaatggtata gtctaaataa agaagagtta ttaaataagg caactgttgg tgaaaagttt
    44941 aatgataaat taaaagaaga gtttctccag gaatggcctt tggataggat tttaacaatg
    45001 tcaatcgatg aatatgtaat aggaaaggga cagcaaaata agtctttatg ctacgctctt
    45061 gagaagggaa aatacaaaaa tctatttctt ggaatttctg gtggctcagc ttcaaaattt
    45121 ggtatttatt ggaataaaaa aacaaacaaa tataaagatc aagctaataa tgagatttca
    45181 gagttggatc agcgattttc aaaattaaaa tcagatttgt atgaaattat caaagaaggt
    45241 attcgtttta actttgaaaa tcctattttt gatatgaaaa gatcaacaaa tgaatttatt
    45301 ggtcgttctg ctatggtgac aaaattactt tgtatctatt ctgagggaga tcctttcttt
    45361 ggtgtaaata ttaatagtca gaaagaattt tggaaccact ttgtttctca gacaaatcaa
    45421 ggtggacctt atctgcaaaa tcataaaata attgaactgg tgtccaaaac ttatcctgag
    45481 ttggagccat cgaaattagg aactatgctt tttgagtatt ctaagctttt tatggaaaat
    45541 aaggaagaca atagtacaat ggattcatca aacaattttc gtcatcaatt aactcaatct
    45601 ctattaaagt ctccaaacct tatccttcgt ggtgctcctg gcacaggaaa gacttatctt
    45661 gctaaagaaa ttgccaaaga attaacggat ggcaacgaag accaaatcgg atttgtacaa
    45721 tttcacccat catatgatta tacggatttt gtagaaggtt taagaccagt atcaaatggg
    45781 gatggagcta ttgagtttag gctacaggac ggtattttta aagatttttg tcagaaagca
    45841 aaagaaaccc aattgattgg aggacaagat aattttgatg aggcttggga ttcttactta
    45901 gaatatataa atgttgctga agaaaaagaa tatataacaa aaacatctta cttatctgtt
    45961 aatagtagac aaaatttgtc agtaaattat gatagtggtg ttccaggatg gtcactacct
    46021 agcaaatatg tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa
    46081 agtggtggaa aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt
    46141 tccccaacag aaattgatac tgataagaaa ttcgtcttca tcatcgatga aatcaatcgt
    46201 ggggagattt ctaagatttt tggcgaactc tttttctcta tcgaccctgg ctatcgtggt
    46261 gaaaaaggaa gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat
    46321 atccccgaaa atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc
    46381 tttgattttg ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt
    46441 ggcatgttgg ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac
    46501 ttgaacgctg ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt
    46561 tattttctta agttgaagga tgtagatttt gactatgaat tactctggtc cgattatatt
    46621 aagcctctcc tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact
    46681 ttgaaaaaag catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac
    46741 aatgaaggtg atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga
    46801 aaaatttgtt gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag
    46861 tctatcccaa gatgaacgta ttttcatttt tccaaatgat ttgactcata ctcctgattt
    46921 ggataaggac caaaagattt ttgaaacagt caatcagaaa atcaagacag ggaacgtgat
    46981 tggttttctt ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag
    47041 taatgaccac tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt
    47101 agatgttgct ttgtctcgtg aagagaggct ttatcaactt ttggtgtatc tctttcccaa
    47161 gtatctacaa gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa
    47221 cgacagtcat gttaagggag tgattgatgt aagaaaccat ctcaagaaaa atcttccttt
    47281 cacgggaata ttgcctacgc aacgagagag ttcacctatg ataatcccct catgcagttg
    47341 gtccgtcaca ctattgaata cattaagaat cagaaaagca ttggtcaagg ggtactagat
    47401 aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa
    47461 ctagctgatc gtgctaagat tattcgggga aatcaatcta aacctatacg tcatgcatac
    47521 tttcacgagt acagaaactt acaagaactt tgtctgatga tcctaaacca agaaaagcac
    47581 ggtttagggt atcaagatca aaaaatctat ggtattctct ttgatgttgc ctggctttgg
    47641 gaagagtatg tttacacctt gttgccaaaa ggttttgtac atcccagaaa taaggataag
    47701 acggatggaa tttcagtatt ttctgttggg aaacgaaaag tatatccaga tttttatgac
    47761 agagaacgaa agattgttct agatgcaaaa tataaaaaac tggaattgac tgaaaaagga
    47821 atcaaccgtg aggacttatt ccagctgatt tcctattctt atattttaaa agctgagaag
    47881 gctggactga tttttcctag tatggagcag tcagtaaata gtgaaatagg aaaagtagct
    47941 ggctatggag ctcaattgaa gaagtggtct attcgaatcc ctcagaatgc ctcattctat
    48001 agtacatttt gtaaaatgat ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa
    48061 gaagtgggga gaaaataatt tcccctcttt cttttatttt taacacaagt aaaactcgaa
    48121 caatatattt caattcataa aataatttga caaaaactgt actttggttt ataataaatt
    48181 aaggaaacgt cggaaaaggc gtagtgatgc aagagtatag gtaggtcatt acaaaagaaa
    48241 cgagacatcg atatgttaaa tgaatttcca atttttgatt acgaagatat tcaattgatt
    48301 ccaaataaat gtgtcattaa aagccgtgca gaagcggata caagtgtcac tttaggaaat
    48361 cacaccttta aactacctgt tgtgccagcg aatatgcaga cgattttgga tgaaaatgta
    48421 gcagagcaac tggctaaagg tggttacttc tacattatgc accgttttga tgaggcagga
    48481 cgcattcctt ttattaaacg aatgcacgat caaggactca ttgcttctat ctctgtcggt
    48541 gttaaggatt atgagtatga tttcgttaga cagctcaaga ctgatgctcc tgagtatatc
    48601 actattgata ttgctcatgg tcatgcggat agcgtgattt ctatgattca acacatcaag
    48661 aaagaattgc cagatacctt tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt
    48721 gaattggaaa atgctggtgc ggatgctact aaggtcggaa ttggtcctgg taaggtttgt
    48781 atcaccaagg ttaagactgg ttttggtaca ggtggttggc agttggctgc tctacgctgg
    48841 tgtgccaagg ctgcgcgtaa accgattatc gctgatggag gaattcgtac tcacggtgat
    48901 attgccaagt ctatccgctt cggtgctagc atgatcatga ttggttccct ctttgcagga
    48961 cacattgaaa gtccagggaa aacgattgaa gtcgatggtg aacagttcaa agaatattat
    49021 ggttcagcct cacaatatca aaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg
    49081 cttcctgcta aaggtcatct gcaagacact ttaactgaga tggaacaaga ccttcaaagt
    49141 gctatttctt atgcaggtgg acgtcaggtt gctgacctta aacacgttga ttatgtgatc
    49201 gtgaaaaact ccatctggaa tggggatgct tcccactaag acggggtctt tgaccaaaaa
    49261 acttgttatt agagcaaatt tctgttataa taaaacaagt ttccaccctt agtgtaatgg
    49321 atatcacgta agattccggt tcttgagatg ggggttcgat tccctcaggg tggatgtaaa
    49381 catcctaaaa agcctttaat agggcttttt tctttatcct gacccaaatt tgccgctaaa
    49441 actgagaatc tctgtctaaa gaattcccaa atgctttcca gtcccgtttt agagtgactc
    49501 agggggcttt ttttgatata ataaaaagga ctgttatcag ttagaaagag gttggtatga
    49561 aagaattaca aactgtacta aagaaccatt ttgcaatcga atttacagac aaaaagttac
    49621 tggaaactgc ctttactcat acgagttatg ccaatgagca ccgcctctta aaaatttcac
    49681 ataatgaacg cttggaattt ttaggagacg ctgttctaca gttattgatt tcagaatatc
    49741 tgtataaaaa atatcctaaa aagcctgaag gtgacctatc aaaactccgt gctatgattg
    49801 tccgtgagga gagtttagct ggttttgcgc gtgattgcca gtttgaccag tttatcaagt
    49861 tgggtaaagg ggaagaaaaa tctggtggtc gcaatcgtga caccattctt ggtgatgcct
    49921 ttgaagcctt tcttggtgcc cttcttttgg ataaggatgt ggccaaggtc aaggaattta
    49981 tctatcaagt catgattcct aaggttgaag caggcgaatt tgagatgatt acagactata
    50041 aaacccatct ccaagagtta cttcaggtca atggtgatgt ggctattcgt tatcaggtga
    50101 tttctgaaac agggcctgct cacgataagg tctttgatgt agaagttctt gttgaaggta
    50161 agagcatcgg tcaaggccaa ggtcgttcta agaaattagc agagcaggaa gctgccaaaa
    50221 atgccgttga gaaggggctg gattcatgta tttaaaggaa atcgaaattc aggggttcaa
    50281 gtcttttgct gataagacca aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc
    50341 caatggatct ggaaagtcca atattacaga aagtctgcgt tgggctttgg gggagtctag
    50401 tgtcaagagt ctccgtgggg gcaagatgcc ggatgtcatc tttgctggaa ccgaaagtcg
    50461 caaaccgctc aattatgctt ctgtagttgt gactctggat aatcatgacg gatttatcaa
    50521 ggatgcaggt caagaaatca gggtggaacg ccatatctat cgtagtggag atagcgaata
    50581 caagattgac ggcaagaaag tccgtctgcg tgatattcat gacctcttct tggatactgg
    50641 attgggacga gattccttct ctattatttc ccaagggaag gttgaggaga tttttaattc
    50701 caagcctgag gaacgacgag ctatttttga agaagctgct ggagttttaa aatacaagac
    50761 tcgcagaaaa gaaaccgaga gtaaactgca acaaactcag gataatctgg accgcttaga
    50821 ggacattatc tacgagttgg ataatcaaat caagcctctt gagaagcaag ctgagaatgc
    50881 ccgtaagttt ttagacttgg aaggacaacg taaggctatt tatttagatg ttctggttgc
    50941 tcaaatcaag gaaaataagg ctgaactaga gtcgacagaa gaagagttgg ctcaggttca
    51001 agaactcttg atgagttatt accaaaagcg tgaaaaatta gaagaagaaa atcaaactct
    51061 taaaaagcaa cgccaagatt tacaggctga aatggccaaa gaccaaggca gtttgatgga
    51121 cttgactagt ctgattagtg atttagaaag aaaattagcc ctatcgaaac tggagtccga
    51181 gcaagtggcc ttgaatcaac aggaggcaca agcccgtttg gctgctttgg aggataagag
    51241 aaattcactc agcaaagaaa agtctgataa agaaagctct ttagctctgt tagagggaaa
    51301 tctagtccaa aataatcaaa aactcaatcg tttagaagct gaattgctag ctttttcaga
    51361 tgatcctgat cagatgattg agctcttacg tgaacgcttt gtggcccttt tacaagaaga
    51421 agcagatgtc tcaaaccaac tgatccgtat tgagaatgag ttggaaaata gtcgtcagct
    51481 ttctcaaaaa caagcagatc aactagaaaa gctgaaagaa cagttggcta cagctaaaga
    51541 gaaggctggt cagcaaaagg ctgagcttga aactgccaag gagcaggttc agaaattatt
    51601 ggccgactat caagtctgtg ctaaggagca agaggagcag aaaacttcct atcaagctca
    51661 acaaagccaa ctctttgacc gtctggataa tctcaaaaac aagcaggcca gagctcaaag
    51721 tttggaaaat atcctgagaa atcatagtaa cttttatgca ggtgttaaga gtgttctcca
    51781 agaaaaaaat cgccttggtg ggattgttgg ggcagtcagt gagcacctga cctttgatat
    51841 gcattatcaa actgccctag aaattgcgct tggagcgagt agtcagcaca ttattgtaga
    51901 agatgagaat gcggcaacca aagccattga tttcctcaaa cgaaacagag ccggtcgtgc
    51961 aacctttctt cctttgacta ctattaaggc gcgtacgatt tctagtcaga accaagatgc
    52021 tatcgctgta agcccaggtt tccttgggat ggcagatgag ttggtgactt ttgatactag
    52081 actggaagcc attttcaaga acttgctagc tacgacggct atctttgata ccgtagaaca
    52141 tgcgcgtgca gcagctcgcc aagttcgtta tcaggttcgt atggtgacat tggatgggac
    52201 agaattacgc acgggtggtt cctatgcggg tggtgccaat cgccaaaata acagtatttt
    52261 catcaagcca gaactggagc aattacaaaa agaacttgct gcagatgaag caagcttgcg
    52321 ttcagaagaa gtggctttga agaccttgca agatgagatg gccagattga ccgagtcatt
    52381 agaagccatc aaatctcaag gagagcaggc acgtattcag gagcaaggct tgttcctcgc
    52441 ttatcagcaa actagtcagc aagttgaaga actggaaact ctttggaaac tccaagaaga
    52501 ggaaaaagat cgtctttccg agggagattg gcaagcggat aaggaaaaat gccaagagcg
    52561 tcttgctgca atcgccagtg acaagcaaaa tctggaagct gagattgaag agattaagtc
    52621 taacaaaaat gccatccaag aacgctatca aaacttgcag gaagagctag cgcaagctcg
    52681 tttgcttaag acagaactgc aagggcaaaa acgttatgaa gttgctgata ttgaacgctt
    52741 aggcaaggaa ttggacaatc ttgattttga acaagaggaa atccagcgcc ttcttcaaga
    52801 aaaggttgac aatcttgaga aggttgatac agaattgctc agtcaacagg cggaagaatc
    52861 caaaactcag aaaacgaacc tccaacaagg tttgattcgc aagcagtttg agttggatga
    52921 tatagaaggt caactggatg atattgccag tcatttggat caggctcgcc agcagaatga
    52981 ggagtggatt cgcaagcaaa cacgtgctga agccaagaaa gaaaaggtca gcgagcgctt
    53041 gcgccatcta caaaatcaat taacagacca gtaccagatt agctatactg aagcactaga
    53101 aaaagcgcat gagttggaaa atctcaatct ggcagagcaa gaggtgcagg atttagagaa
    53161 ggctattcgc tcactgggac ctgtcaactt ggaagctatt gaccagtacg aagaagttca
    53221 cagccgtctg gaatttctaa atagtcagcg agatgatatt ttgtcagcga aaaatctgct
    53281 ccttgagacc attacagaga tgaatgatga ggtcaaggaa cgctttaaat caacctttga
    53341 agctattcgt gagtccttta aagtgacctt caagcagatg tttggcggag gtcaggcaga
    53401 cttgatattg actgagggcg accttttaac agctggtgtg gagatttctg ttcaacctcc
    53461 aggtaagaaa atccagtcgc ttaacctcat gagtggtggt gaaaaagctc tatcggctct
    53521 tgccttgctt ttctccatta ttcgtgtcaa gaccattcct tttgtcatct tggatgaggt
    53581 ggaagctgcg ctggatgaag ccaatgttaa acgttttggg gattacctca accgctttga
    53641 caaggacagc cagtttatcg tcgtaaccca ccgtaaggga accatggcag cggctgattc
    53701 catctatgga gtgaccatgc aagaatcggg tgtttcaaag attgtttcag ttaagttaaa
    53761 agatttagaa agtattgaag gatgacaatt aaactagtag caacggatat ggacggaacc
    53821 ttcctagatg ggaatggacg ctttgatatg gatcgtctca agtctctctt ggcttcctac
    53881 aaggaaaaag ggatttactt tgcggtggct tcgggtcggg gatttctgtc tctggaaaaa
    53941 ttatttgctg gtgttcgtga tgacattatt ttcatcgcgg aaaatggcag tttggtagag
    54001 tatcaaggtc aggacttgta tgaagcgact atgtctcgtg acttttatct ggcaactttt
    54061 gaaaagctga aaacgtcacc ttatgtagat atcaataaac tgctcttgac gggtaagaag
    54121 ggttcatatg ttctagatac ggttgatgag acctatttga aagtgagtca gcattataat
    54181 gaaaatatcc aaaaagtagc gagtttggaa gatatcacag atgacatttt caaatttaca
    54241 accaacttca cagaagaaac gctggaagct ggggaagctt gggtcaatga taatgtccct
    54301 ggtgttaagg ccatgacaac tggctttgaa tctattgata ttgttctgga ctatgtcgat
    54361 aagggtgtag ctattgttga attagctaaa aaacttggta tcacaatgga tcaggtcatg
    54421 gcttttggag acaatcttaa tgacttacat atgatgcagg ttgtgggaca tcctgtagct
    54481 cctgaaaatg cacgacctga aattttagaa ttagcaaaga ctgtgattgg tcaccataag
    54541 gaccagtcgg ttatagctta tatggagggc ttataatggc agatataaaa ttaatcgcat
    54601 tggacttgga cggtaccttg ctgactactg ataaaaggtt gacggatcgt accaaggaaa
    54661 ccttgaaagc tgcgcgtgat cgtggtatca aggtcgtatt gacaactggt cgtcccttaa
    54721 aagctatgga tttctttctc catgagctag gaactgacga ccacgaagat gagtatacga
    54781 ttacttttaa tggtggttta gttcagaaaa atacaggaga aatccttgat aaaacagtct
    54841 tttcatatga tgatgtggca cgtttgtatg aagaaacaga gaaattatca ctgcctcttg
    54901 acgctatctc agaaggaact gtttatcaaa ttcaatcgga ccaagaaagt ctttatgcca
    54961 aattcaatcc agctttgact tttgttccag ttgactttga agacctgtct agtcaaatga
    55021 cctacaacaa atgcgtgacc gcctttgctc aagaaccctt ggatgcagcc attcagaaga
    55081 tttctctaga attgtttgac caatatgaaa tctttaaatc acgtgaaatg ttgctagaat
    55141 ggtcaccaaa gaatgttcat aaagcaacag gtttggcaaa actaatcagc catcttggaa
    55201 tcgaccaaag ccaagtgatg gcttgtggtg acgaggccaa tgacctctct atgattgaat
    55261 gggcaggtct tggtgttgct atgcaaaacg ctgttcctga agtaaaggca gccgcaaatg
    55321 tagtgacgcc gatgaccaac gatgaggaag ctgtcgcctg ggctatcgaa gaatatgtgc
    55381 taaaggagaa ctaagatatg ggattgtttg accgtttatt cggaaaaaaa gaagaaccta
    55441 aaatcgaaga agttgtaaaa gaagctctgg aaaatcttga tttgtctgaa gatgttgatc
    55501 ttaccttcac agaagctgat gaagttcctc aggaagaagc agaggttgaa attgttgaac
    55561 aagctgtgtt ccaagaagag gaaatccaag acacagttga agaaagtcag gattcagagc
    55621 cagctgtagg ggtttctcaa gaagaaatag aagaattacc aaactcagaa gaattagcag
    55681 aggaagagaa gcttgagcac gaaggaactg tagaagaaaa taattctgaa attcttgaag
    55741 cagaaaggcc tcaaacagaa gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa
    55801 ctcgcacagg tttcggtgcc cgcttgaatg ccttctttgc taacttccgc tctgttgacg
    55861 aagaattttt cgaggaactg gaagaactgc tgattatgag tgatgttggt gtccaagtcg
    55921 cttctaactt aacggaggaa ctacgttacg aagccaagct tgaaaatgcc aagaaacctg
    55981 atgcacttcg tcgtgtcatc attgagaaat tggttgagct ttatgaaaag gatggtagct
    56041 acgatgaaag catccacttc caagataact tgacagttat gctctttgtt ggtgtgaatg
    56101 gtgttgggaa aacaacttct atcggaaaac tagcccaccg ctacaaacaa gctggtaaga
    56161 aggtcatgct ggttgcagca gataccttcc gtgcgggtgc agtagctcag ctagctgaat
    56221 ggggccgacg agtagatgtt ccagtagtaa ctggacctga aaaagctgat ccagccagcg
    56281 tggtctttga tggtatggaa cgtgccgtgg ctgaaggtat cgatattctc atgattgata
    56341 ctgctggtcg tctgcaaaat aaggataatc ttatggctga gttggaaaag attggtcgta
    56401 ttatcaaacg tgttgtgcca gaagcaccac atgaaacctt cttggcactt gatgcatcaa
    56461 caggtcaaaa tgccctagta caggccaaag aattttcgaa aatcacacct ttaaccggaa
    56521 ttgttttgac taagattgat ggaactgctc gaggaggtgt ggttctagcc attcgtgaag
    56581 aactcaatat tcctgtaaaa ttgattggtt ttggtgaaaa aatcgatgat attggagagt
    56641 ttaactcaga aaactttatg aaaggtctct tggaaggttt aatctaatca gaagcaaaaa
    56701 tcctgcaagg cataaacttg caggaaattt ttttattcta agcgaccatc ttgacgatag
    56761 gcgatatctg gttgccaagt ccatttggca ccgaattttt caagtaggtc aaagctggct
    56821 tgaggtccca tgcttccagc tttatagtca tgaagtgggg caccattttc agcccagagc
    56881 ttttcaatac gatcaatcaa cttccatgac gcaccaactt catcccagtg gctaaagtta
    56941 gttgagttgt tatttaggac atcataaatc aatttttcgt atggttctgg agaagcacca
    57001 gttgcagtcg cgtctgtacg ataatcaagt gagttaggag ccaagttaaa ttcttctcct
    57061 acttgcttcc catttaggct aagagagaag ccttctgttg gttgaatata gatggtcaaa
    57121 atatttggag caagtggttc tccaaagata gaatccattt gtttaaagac gatgttgaca
    57181 tgagttcctt tttcagtcag tcgtttacct gtacggaaaa agaaaggaac accacggaat
    57241 cgatcgctgt ctacaaagaa ggcaccagat gtaaaggttt cagttgttga ttctggattc
    57301 acatttggct cgctacgata agagatgtat ttcatgccat caatcttacc agagcggtat
    57361 tgcccacgga taaagtgttc tttgagttct tcatcagttg gatgatagag gtttttaaag
    57421 accttaatct tttcagcacg aatctcgtct tttgtgaagc ttgctggttt gtccatggcg
    57481 agaagcgaaa gaagttgtag agtgtggttt tggaccatgt cacggagggc accggattgg
    57541 tcatagtagc caccacgttc ttctacaccc aagcgctccg caaaggtaat ttgaacattg
    57601 tcgataaaat ccttgttcca aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag
    57661 atgctttgga tcatttcctt accaagataa tggtcgatac ggaaaatttg ttcttcgtca
    57721 aatgttgcta ggagttcgtc attcaacttg cttgcagttg cgtaatctgt accaaatggt
    57781 ttttcaacga tcaagcgctc aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt
    57841 ttggcaatgg ttccaaagaa ctgaggtgcc atagacaaga agaagagctt attgtgttca
    57901 gcttggtatt tttcattaag ctcagcttgt aattgactca aagcaatata atgttccgaa
    57961 tcattgacat catggctttg atagtagaag tggctagcaa attcttgggc ttgctcggta
    58021 ctatctgcca aatcaaggat ggactcgaca actacagatt caaaatattc cttactccaa
    58081 ggtctacggg cagttccaat aacggcaaag tgcttggaaa gattgccgga ttgatatagt
    58141 ctaaaaaggg aagggtagag cttgcgttta gccaggtctc cactcgcacc gaaaattgta
    58201 acaataacct tagatgacat ctagctacct aatttctatt tttattccta gtcttgctag
    58261 gtatgaggaa acctcatttc ataaacttaa ttctaacata attttccgaa aaatcaaaaa
    58321 ttccaatacg aggtagaaaa actgcaagga aatccttaca gtttgagttt agacgtttaa
    58381 gaccttatct aagaactctt tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg
    58441 tgttccgtct tcaaggaact cgccatctgc agtaaagata acgcggttgg caacctgacg
    58501 agcaaatccc atctcatggg ttacgataat catggtcatg ccttgctcag ccaattcctt
    58561 cataacgtta agtacgtctc caaccatctc agggtcaagg gcagaagttg gttcatcgaa
    58621 gagcatgatg tctggattca ttgctaggcc acgagcgatg gccacacgtt gtttttgacc
    58681 acctgatagg ctatctggat tggcattagc tttatctgct agtccaacct tttcaagcaa
    58741 ctccattccc aattcctcag cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa
    58801 ggtgatgttg tccaatacag acatatgagg gaagaggttg aagtgttgga ataccatgcc
    58861 gatattttca cggacgtggt caacattggt tgttttttca gttaaatcat agccgttcac
    58921 agtgatgtga ccgctagtga cttcttctaa aagattgagg ctacggagga aagttgactt
    58981 accagaacct gaaggaccga tgatacaaac aacatctcct tcatagaact tagtcgtaat
    59041 tccttttagg acttcatttt ttccatagtg cttgtgtaaa tcatttacat caatttttaa
    59101 ttttgccatt aacgaatcct cttttctaag cgtttcgcta gtctagtcaa aagtgtgata
    59161 attacaagat agaagatagc aaggattgca tacatcttga aactttggta gttacgagca
    59221 atgataatct taccagtttg gaagagttca accaaaccga tagcagatac gatagttgta
    59281 tctttaagag cgataacgaa ttggttgaca aagtttggca acatcaattt agttgcttgt
    59341 ggcaagataa tcttacgcat ggtttttcca taagagatac ccaagcttcg gctggcttcc
    59401 atttggccaa ctggaacggc ctgaatacca ccacgaacga tttcagcgat ataagcagcc
    59461 gcattgagtg agagggcaat ggttccagct acaaagtcgt taattgggct ttgttggcct
    59521 gtgatagact cgatgaagtt tggaattccc cagaagatga aggctgcaag aatcatcaat
    59581 ggaataccac gaataacgtc aacgaaaatc tcagagatga cgcgaagaga tttgtatggg
    59641 ctaacgctaa acataccgaa gataattccg atgacaatgg caatagcaaa tgagataaga
    59701 gctagagcaa gagtgatacc aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag
    59761 ccccagagcg ttgtttcgtc aacagtactt gttgaagcag ttgaagattc gctagctagg
    59821 tatttgtcaa gaatcttttg gaattcaccg tttgccttaa ggtttgcaag tccgttgttg
    59881 aacatttcaa tcagttctgg atttgctcct tttttaacgg caaaggctgt ttcaccgatt
    59941 ggagttccag agattggagt tttcaatttt tgaccttggc tgatagaata tttgagaaca
    60001 ggttcatcat ccataacggc atcaatggca ccagtgttta aactgtcata cattgaagaa
    60061 ccatcagcaa aggttttgat tttgtaaccg tatttgcttt gattttctgt taggaaggtt
    60121 tgagaagcag ttccgttttt aacaccgact gtctttcctt ttagatcttc ataagaagca
    60181 atattgcttg attctttgac accaagaatg gtattagcag tgtagtatga ttctgagaag
    60241 tcaaaagttg ccttacgagc atctgtgaca gacataccag caatgatacc atcggcttga
    60301 ccagcttgga cagcactaat agcagcatca aaaccagggt tggtgatttc aatttcaaaa
    60361 ccttggtctt tagcgattgc cttaatcaat tccatatcaa taccagtgta ttggttgctt
    60421 gaattttgga aaacaaaagg tgcaaaagaa gaatcgctgg caatgatata tttagcctta
    60481 acaggaatag cttttaatcc tgcgagagta gttgtagttg gcactgctga agatgatgaa
    60541 gcagtccatt tcttgataat tttatcaaga ctaccatctt ttttcatttc agccaaggct
    60601 tggttaaatt cagtaaccag gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa
    60661 cttcctacag cttcaccatc catttcaata tggaggtctt gaccttggtt aatggcatat
    60721 tcgataacag gtttgtcatc catcatggca tcgatggcac cagcactcaa gctgttgttc
    60781 attaaatcac cagtgtcaaa tgttttaata gtaaagccgt atttatcttt gattgtttca
    60841 aggaaacgtt gagcggcagt tccgttttta acaccaacgg ttttgccagt taattggtcg
    60901 tacttgctaa ttttgtgtga ctttgtagta gcaatgacaa cttttgtatc atagtaagta
    60961 tcagacatgg tgaagacttt ttcacgttct ttagtctttg tcatccctgc catgatagcg
    61021 tcggcttgcc cagcttgaac cgcattgact gctgcgtcaa atccaggata ggacatctga
    61081 atgttccagc ctttaatctc agcgactttg ttaataatgt caacatcaat tcctttataa
    61141 gtttgatctg aatctttaaa ctcaaaaggt gcataggcgg tatcagaaac aatcttaatc
    61201 gtttctgctt tggcaatacc taatgagaaa attgggaata aaattagcaa aaatgctaga
    61261 aattttttct tcatttttag tctccttttc cgaatattct ctcattatat cagaaaaagt
    61321 aaaaaaaggc aaatttttat atttttcgtg tcagaaaata taacattgat ttttcctttt
    61381 ctttcttgaa ttgctattaa aaagtgctat aataatagta tatatagaag aaaagaggac
    61441 ggggatatga agaacaaaag aatatttaaa gacttccaag cttcaaaaat gaatttaaac
    61501 atttacacaa gccccttgtt agcctttgtt tttgtcttca taggagagtt tgtggcttat
    61561 actttatatg gtattagttt gttagctctc atcggacttg ctagaaattt tggagaggct
    61621 ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt
    61681 gactttcgtt taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga
    61741 tggacaagaa aagttgagaa aagacctatt cgaaccttgg gattttatag agagaatttc
    61801 ctcagcaatc ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta
    61861 ggtttagtgg tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattctctt
    61921 gcctttgtcg tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg
    61981 gcccgtgctt ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt
    62041 atatctagcc tgttctttac cctgcttcat atgggcaatt ctggcctcac ccctctatct
    62101 ctagtaaatc tctttttatt cggagttacc atggctcttt accttctcaa aactgataca
    62161 gtttggggtg ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg
    62221 attttagtta gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat
    62281 caagattggc tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta
    62341 ttactactgc tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga
    62401 cttcggtccg tccttttctt cgtgaaaata ctataagtat gctaaaatag ggatagcaca
    62461 tggagagagg attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa
    62521 atatcaacca tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg
    62581 gggagaaaaa gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag
    62641 tcaggtcatt tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc
    62701 cggtcagctc tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt
    62761 atcctactat gattattacc agccagaggc ctatgtccct tctagcgata cctatattga
    62821 gaaggatagt tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct
    62881 tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc
    62941 gcccaaggaa tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga
    63001 taaactcttg aatgacttgg tcgatattca gtttgaacgt aatgatattg atttccaacg
    63061 cggaagattt cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca
    63121 tgcctttcga gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct
    63181 gacaggtcag gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt
    63241 gaccaatgac gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca
    63301 attagctgtc tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac
    63361 agagtatgat atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc
    63421 tcgccacatg gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc
    63481 agatgatttc ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat
    63541 gtacaatgga gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc
    63601 tgctttggac aatcgtcctc tccgtcggga ggagtttgag agtcacgttc atcagattgt
    63661 ttacgtttca gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca
    63721 aatcattcgt ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca
    63781 gattgatgac ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat
    63841 cacaactttg accaagaaaa tggcagagga cttgaccgac tacttcaagg aaatgggtat
    63901 caaggtcaag tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga
    63961 cctgcgcttg ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga
    64021 cgttcctgaa gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa
    64081 cgaacgtgga ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat
    64141 catgtatgca gatacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg
    64201 tcggaaaatt cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa
    64261 agaaatccgt gacctgattg ccgtgaccaa ggcagttgct aaggaagagg acaaggaagt
    64321 cgacatcaat agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca
    64381 aatgcaagaa gccgtcgaag tgcttgactt tgaactggcg gctcagatcc gtgatatgat
    64441 gttggaagtc aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag
    64501 agaagatttg atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca
    64561 gtatgatgct ccctattatg atgattatca gtatttttca aattttaaag aattcgaact
    64621 acaaaaatca gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa
    64681 actagttggg actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg
    64741 aattggtatt tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca
    64801 gtggatagat aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg
    64861 gtcagggaat cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca
    64921 tattccaaaa gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt
    64981 gagagaagac tgggagaaaa tgaatgacgg ttattatcaa atcaatggaa actcctgaag
    65041 agatagaagg taaatccctt gttcactggc aaacgtggag agaggcttat gatgaccttt
    65101 tgcctgcaga atttcaggag acaatgacat tagaaagatg tcgattcttt agtcaaaagt
    65161 atccagaaaa tacattgatt gcgatagatg gccttaaggt aattggtttt atcagttatg
    65221 gcaactttcg tgataagact atgcaagctg gtgaaattat tgctttatat gttttaaaag
    65281 actattatgg aaaaggcatt gcacaaaagt tagtgaaagc agctttgact gctcttgatt
    65341 ctttttctga aattttctta tgggtattga aagataataa gcgcgccatt gctttctatc
    65401 aaaaaatggg ttttactttt gatggtcaag aaaaaatgct tgaacttgga aagcctataa
    65461 aagaaagacg gatggtgttc tattctaaat aattttaaaa agtagaagct agaatctctg
    65521 gtactaaatc tgaaaattta ataacttaga aagcgagtaa atttatgtcc cgttcccaat
    65581 taacgatttt aacaaacatt tgtctgattg aagacctcga aactcagcgc gtggtgatgc
    65641 agtaccgtgc tcctgaaacc aatcgttggt ctggttatgc ctttccagga ggccatgtag
    65701 aaaacggcga gtctttcgca gagtctgtca ttcgtgaaat atatgaagaa acagggttga
    65761 ctatccaaaa tcctcaactt gtcggcatta aaaattggcc actagataca ggtgggcgct
    65821 atattgtcat ttgttataag gcaactgagt tctctggtac ccttcgctct tcagatgaag
    65881 gagaagtttc ttgggtgcaa aaagaccagc ttccaaactt ggatctggcc tatgatatgt
    65941 tacccttgat ggagatgatg gaagctccgg acaaatctga atttttctac cctcgccgta
    66001 cagaagacga ttgggaaaag aaaattttct agtcttttac taaataacct agctgatcca
    66061 aggcctcctc gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga
    66121 caccatctgt taattcagat aaaggtctaa aatcagaatg ctcgacttgt tctagaaaat
    66181 gttgaacatc tctgcggcaa gacagtttaa gcaaggtttc aatttctcca taaacgggat
    66241 ggtcaatcaa agtattctgg acacgtcctc cattatcgac gatagcaagg agttcttgac
    66301 cgatttcttc aacttcatgt ttcaccttga aaagtttatg gacataagga ttggtatcaa
    66361 tttgcttata gacgtagcca cgattagtag ataggatagg agcgccatcg gctctcaaaa
    66421 ttgcaatgtc ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc
    66481 cattaagggc tttaggagct tctttcaaga gttggagcag agattgtttg cgatcttttg
    66541 tcatagcttt tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt
    66601 atagtctacc atactatgta taattgtacc aaatccaact agcacaaata gaacataaaa
    66661 catattttct acattggtac cagaagttgc gtaaaaaagg acacaggcta atacttcagc
    66721 aagggcatgg ataagcgcta aaacaaagtt aaaaacccaa gaagattttg gtttatctag
    66781 ggtatcgggg aatttttgta ggtaaagagc ccccaaagtc ccaaaaaaga tatgggaaaa
    66841 agctcgaaaa acgataacca tgggatagcc agccatcaaa aatccaaaac tagaggctag
    66901 gatgacaaaa atagccatca agggcgacaa gaacatggcg ataaaaatag cgatgtggct
    66961 ccccaaagtg taagaagcag gaggaatgac aatcttaaag ggcataacaa ttggaatcaa
    67021 aatcgcaata gccgttaaga gggctgtcat tgtcataaat tgtgtctttt tccgtgtgtt
    67081 cataagaatc tcctttttat ctgtatatac actagtatag tacaataaag aagacaataa
    67141 agcaaggatt tacttgggtt tataggtcat tttttagttg aaagttggta aagatttcac
    67201 taaaaagaaa ctacttcaaa caaaatctcc accttcaggt ttgaaagtgg agattgtttt
    67261 tatttcttca aagtttgtag tcttggaaca atggctaagg ttagaactgc ggaaatgact
    67321 aattcagcaa ttgagtttgt tgagataact gttgctagga gtttttggat attaccatca
    67381 aaaacatttc caaaaaggta gaaaattcca ccaagtacaa agactgtgtt ggtaagtgaa
    67441 ccaagggcac cagctagaat tagcccagtc ttgtttttca ttagtttata gaccagataa
    67501 ggagttaaac caatcaaaat acgtgggacg atggcaatga tagctgagta gatattccca
    67561 tttggtacga aaggagagaa gaggtaactt gttggaagga tagtaattgt gttgacggtt
    67621 aaactaagta gtcccatcaa gaaaccaagt gtaacaccaa cgcgtggacc gtaaataatg
    67681 ctggcaataa tgacaggaat atgaacaatg gtcggtttga ttggaaatgg aaaaaggtta
    67741 aagataagtg agctcagaaa gtgtatcacg agcatggtag caaaaaagat agcaatgggt
    67801 gcaatattag agcgtttttt catcgatagt ttcctttatt ctttctaaaa taattgtgag
    67861 gtcagctaaa gctcctcgtc cgtggtctcc acaagctagt agggattcct taggagcaat
    67921 cagctgatag ccgtaggttt ctaatgtttt cagattattc tgagttactg gatggtcata
    67981 catttttgta ttcatagcag gagttattag tttgggaata tgacttggta gggctagagc
    68041 tgtactggtt accatgttgt ccgcaaatcc gtgagctagt tttgcaatag tgttagcagt
    68101 tgcaggtacc acgataaata aatctgcttt ttttccaagt tcgatatgat tgacctgatc
    68161 aggatagggt tccttcatga catccaagtg gacaggattc tgtgagagta cctgtagtgt
    68221 caaaggttgg ataaactctg tagcagcctg agtcattaag acagtgactt gatggccttg
    68281 tttttttaga gaactgacta aatctgccga cttataagag gcgattgaac ccgttacagc
    68341 caagagaatg tttgccatag ttttcctttc taagaatgat aggcttgaat tttttcaagg
    68401 aggagttctg caatttcttc tttagtctgg actgtttgaa gctgattttt ctcaacaaat
    68461 atagctcggt gctgatctgt tgaaatttga gtcaggtcat tcgcgatgat taaatctgct
    68521 tgattcttga taagactttt tcgtgcaatg tcaaccagat gatcttcggt aacatcaacc
    68581 agcagtttga aaccaatcag atgaatagta ggattccatt ccttgactag ggatatgatt
    68641 ttgggtgtct ttttaaggaa caaaacctga acctcatcag ttgaagaaat cttggcctga
    68701 tgattctgct tgcttaaaaa ttcttttaga ttggagctag cctgaacttc ctcaagccct
    68761 gtcatataaa caggagtgta gtcagaaaca gccattgagt ggatcaagac ctgataatcc
    68821 tgaacacgtt cttgcatttc tattagaagg tctttggtat tggtaatttc tcgaatactt
    68881 aggttaggat gaggctctgg cttcagagct cgttttgtcg taattaaaca aacttcatgc
    68941 cctgcagaaa gcaaagtctc tgtgataatt ttccccaagt gacctgtaga atggttagtg
    69001 atagagcgga cgctatcgat agtttcactg gtaccgcccg atgtaactaa aattttcata
    69061 gcactattgt acacaaaaat aagcggtaag taaaatgaaa gtgataaatt tttggtaaaa
    69121 acgaagattt attatagttt caaactataa agccatataa aatttaagaa aggactctaa
    69181 aagtcttaaa aacagagata tttacgaacg tttagagagt tttaagatgt taaaaatctt
    69241 gttttgtgat ataatgaatt atcatataag aggttagagg aattttgaat gaaaacagat
    69301 attgaaatcg cacagagtat tgagttgaag ccaattgttg atgttgtaga gaaacttggt
    69361 atttcttacg acgatttgga gttgtacgga aagtacaagg ctaaactcag ctttgataaa
    69421 attcgtgcag ttgagagcaa tccagtcggt aaattgatct tggttactgc catcaaccca
    69481 acacctgcag gtgaaggaaa gtcgacgctt accattggtc ttgcggatgc cttgaacaag
    69541 attggcaaga aaaccatgat tgctatccgc gaaccgtctc ttggtccagt catggggatc
    69601 aagggtggtg ctgctggtgg tgggtatgca caagttctgc caatggaaga catcaacctc
    69661 cactttactg gagatatgca tgctattaca actgccaaca atgccctttc tgccttgatt
    69721 gacaaccact tgcaccaagg gaatgagctg ggaattgatc aacgtcgtat cctctggaaa
    69781 cgcgttgtgg acttgaacga ccgtacgctc cgccatgtga ctgttggtct tggtggtcct
    69841 ctaaacggta ttccacgtga ggatggtttt gatattacag ttgcttcaga aatcatggca
    69901 attctttgct tggcaacgga catcgaggac ttgaaacgtc gtttggcgaa tatcgttatt
    69961 ggttatcgct atgaccgtac gcctgtttct gtaggtgatt tgcaggttga gggtgccttg
    70021 gctttgattt tgaaggatgc tattaagcca aacttggttc agacaattta cggtacacct
    70081 gcctttgtac acggtggtcc atttgccaat atcgctcatg gctgtaactc tgttttggcg
    70141 acgacaacag cccttcactt ggctgattac actgttactg aagctggttt tggtgcggac
    70201 cttggtgctg agaaattcct tgatatcaag acaccaaact tgccaacatc tccagatgca
    70261 gttgttattg tcgcaaccct tcgtgccctt aagatgaatg gtggtgtggc taaagacgct
    70321 ctgactgaag aaaatgtaga ggcagttcgt gcaggttttg ctaacttgaa acgccacgtt
    70381 gaaaatatcc gtaagttcgg tattccagca gttgtagcta ttaacgaatt tgtatctgat
    70441 acagaagctg aaattgcagc cttaaaagaa ctctgtgcct caatcgatgt accagttgaa
    70501 ttggctagtg tctgggctga tggagcagaa ggtggagtag cacttgccga aacagttgtt
    70561 aagacaattg ctgaaaatcc agctaactat aaacgtttgt atgataatga cctttctgtc
    70621 caagaaaaga ttgaaaaaat tgtcactgaa atctatcgtg gtagcaaagt gaactttgag
    70681 aagaaagctc aaacacaaat tgctcaaatc gttcaaaacg gttgggacaa attgccaatt
    70741 tgtatggcta aaactcaata cagtttctca gacaatccaa atgcgcttgg agcaccagaa
    70801 aactttgaaa ttaccattcg tgaattggta ccaaaattag gtgcaggctt catcgttgcc
    70861 ttaactggtg atgttatgac catgccaggt cttccaaaac gtccagcagc tctcaacatg
    70921 gatgttgaaa gcgatggaac tgtactaggc ttgttctagt ggattgaaat tgactttaag
    70981 tgagtttgga aataatatcc aagctcattt tttctcagac tgcaagcagt tcatcaataa
    71041 gatttatact cttcgaaaat cttttcaaac tacgtcagct tcaccttgcc gtaggtaata
    71101 tgatactgac tctgtcagtt ctatccacaa cctcaaaaca gtgttttgag caacctgcgg
    71161 ctagcttcct agtttgctct ttgattttca ttgagtataa gtagatagaa aagttatata
    71221 ctatctattg aaaatattat aaatcagata taaagacagg tgaaaccttc tgtgttatac
    71281 tagagatatg ttagatttga aagaatacgg tatcgtcatg tggccggagg agaaagtcat
    71341 ttctttccgt gagaaacttc tcgcttggta tgatgaaaac aaaagagatt tgccttggag
    71401 gagaagtaaa aatccttatc acatctgggt atctgaaatc atgcttcagc agaccagggt
    71461 ggatacagtt atcccttact acgaaagatt tttggactgg tttccaactg tcgaaagtct
    71521 ggcaactgcg cctgaggaga gtttactgaa agcttgggag ggcttgggtt attattctcg
    71581 agttcgcaat atgcaggctg cagcccagca gattatgact gactttggtg gccaatttcc
    71641 aaatacctat gaaggaattt ccagcttgaa agggattgga ccttacacag caggagccat
    71701 ttccagtatt gcttttaact tgcctgagcc agctgtagat ggtaatgtca tgcgggtctt
    71761 ggcgcgtctg tttgaagtca accacgatat tgggattcca agtaatcgaa aaatttttca
    71821 ggcaatgatg gagatcttga ttaatccaga tcgtccgggt gattttaatc aagcctttat
    71881 ggacttaggg tctgatattg agtctcctgt aaatcccaga cctgaagaaa gcccagtcaa
    71941 ggactttagt gcggcatatc agaatggaac catggaccgt tatccaatta aatctcctaa
    72001 gaaaaagccg gttcctattt atcttaaagc cttagttgtg aaaaattctc aaggacaatt
    72061 tttacttgaa aaaaatgaaa gcgaaaagct cttggcaggt ttttggcatt tcccctttat
    72121 agaagttgat aacttttcgc aagaagagca gtttgacctc tttcatcagg ttgcggaaga
    72181 aagtgtgaac tctggcccca gtccagaaga gagtttccag caggactatg acctagatgt
    72241 tgattggctt gatgtttgtt ttgatacagt ccagcatgtt tttagtcatc gaaaatggca
    72301 tgtacagatt gtagcaggtc aggtgagtga cttccatgat ttttcagata gggaagttcg
    72361 ttggctttca ccagaagaat tcaagaatta cccacttgcc aaaccccaac aaaaaatctg
    72421 gcaggcttat gcacaagcca acttagacag tagccaagac tagctattgt gtcttctgac
    72481 tattttttgg tataatagta gagaaaaagg tgaacatatg aaaaaaatac taattgtaga
    72541 tgatgagaaa ccaatctcgg atattatcaa gtttaatatg accaaggaag gttacgaagt
    72601 tgtaactgct tttaatggtc gtgaagcgct agagcaattt gaagcagagc aaccagatat
    72661 tattattctg gatttgatgc ttccagaaat tgatggttta gaagttgcta agaccattcg
    72721 taagacaagc agtgtgccca ttcttatgct ttcagccaaa gatagtgaat ttgataaggt
    72781 tatcggtttg gaacttgggg cagatgacta tgtaacgaaa cccttctcca atcgtgagtt
    72841 gcaggcgcgt gttaaagctc ttctgcgtcg ttctcaacct atgccagtag atggtcagga
    72901 agcagatagt aaacctcaac ctatccaaat tggggattta gaaattgttc cagacgccta
    72961 cgtggctaaa aaatatggcg aagaactaga cttaacccat cgtgaatttg agcttttgta
    73021 tcatttagca tcgcatacag gtcaagtcat cacgcgcgaa cacttgcttg agactgtctg
    73081 gggttatgac tattttggtg atgtccgtac agttgatgtg actgtacgac gtctgcgtga
    73141 gaagattgaa gatacgccca gccgaccaga gtatatcttg acgcgccgtg gtgtagggta
    73201 ttacatgaga aataatgctt gatttactga aacaaaccat ttttaccaga gattttatct
    73261 ttatcctgat tttgttaggt ttcatccttg ttgtgaccct cttattactg gaaaatagac
    73321 gtgataatat tcagttgaag caaatcaatc aaaaggttaa agatttgatt gcaggagatt
    73381 attccaaggt tcttgatatg caaggtgggt ctgaaatcac caatattacc aataatttga
    73441 atgacttgtc ggaggttatt cgtctcactc aggaaaatct agaacaagag agtaagaggc
    73501 taaatagtat tctgttttat atgacagatg gggttcttgc gaccaaccgt cggggtcaga
    73561 ttatcatgat taacgataca gccaagaagc aactggggtt ggttaaggaa gatgttctga
    73621 atagaagcat tttggaattg ctcaagatag aagaaaacta tgaattgcgt gatttgatta
    73681 cccaaagtcc agaattgttg ctagattccc aagatatcaa tggcgaatat ttgaaccttc
    73741 gagttcgctt tgccttgata cgtcgagagt ctggctttat ttcaggtttg gtggctgttt
    73801 tgcatgatac gacggagcag gagaaggaag aacgcgaacg aagactcttt gtttccaatg
    73861 ttagccatga gttacggact cctctgacta gcgtaaaatc ctatcttgaa gccttggatg
    73921 agggggcttt gtgtgaaact gtagcaccag actttatcaa ggtttctctt gatgagacca
    73981 accgtatgat gcgcatggtg acggatctcc tccatctttc acgtattgat aatgctacca
    74041 gtcacctaga tgtggaactg attaacttca ctgcttttat tacctttatc ctcaatcgtt
    74101 ttgacaagat gaaaggacag gaaaaggaga aaaaatatga gttggtgaga gattatccca
    74161 tcaattctat ctggatggaa attgatacag ataagatgac gcaggttgtc gacaatattt
    74221 taaataatgc tattaagtat tcgccagatg ggggtaaaat cactgtcaga atgaagacaa
    74281 ctgaagacca gatgatttta tccatttctg accacggttt ggggattcct aagcaggatt
    74341 taccacgtat ctttgaccgt ttctatcgtg tggatcgtgc tagaagtcgt gcacaaggtg
    74401 gtacaggtct aggactgtct atcgctaaag aaattatcaa acaacataag ggctttattt
    74461 gggccaagag tgaatacggc aagggttcaa cctttaccat tgtgctccct tatgataagg
    74521 atgcagtgaa agaagaagta tgggaggatg aagtagaaga ctagaatgag tgaaataggc
    74581 tttaaataca gtattttagc gtcgggttcc agtggaaatt ctttttatct ggaaacctca
    74641 aaaaagaagc ttttagtaga tgcaggcttg tctggcaaga aaattaccag tctgctagct
    74701 gaaattaacc gtaagccaga agacctggat gccatcttga ttacccatga gcattcagat
    74761 catatccatg gagtaggcgt tttggctcgc aagtatggta tggatcttta tgccaatgaa
    74821 aagacctggc aagctatgga aaatagtaaa tatcttggca aggtggattc ttcgcaaaag
    74881 catatttttg aaatgggtaa aaccaaaacc tttggagata tcgacatcga gagttttggt
    74941 gtaagccatg atgcagtcgc accgcagttc tatcgcttta tgaaggatga taagagtttt
    75001 gtccttttga cagatacagg ttatgtcagt gaccgtatgg cgggcattgt cgaaaatgcg
    75061 gatggctatc ttatcgaggc caaccatgat gtagagattt tgcgatcagg ttcttacgct
    75121 tggcgactca aacaacgaat cctatctgac cttggtcacc tttctaacga ggacggtgct
    75181 gaagctatga ttcggacgct aggaaatcgt actaagaaga tttaccttgg gcatttatct
    75241 aaggaaaaca atatcaagga actggctcat atgaccatgg tcaatcagct ggctcaagct
    75301 gatctgggag tcggagtaga ctttaaggtt tatgatacct caccagatac cgcaacacca
    75361 ttgacagaga tatagaaaga acgctgagaa ggtgttcttt ttatattgac tgaacaccta
    75421 aaaagtaata caatggtgtt accattaaaa aagggagcac aaaagatgac tactattaca
    75481 ttaaaagttt ctgaagctga taaaacattt atgaaagcaa tggctaagtt tgaaggagtt
    75541 tccctttcgg aacttattcg caccaaaact cttgaagccc tagaagatga atacgatgct
    75601 cgtgtggcag atttagccta tcaagagtat ttagaagact tggaaaaagg agttgaaccc
    75661 attacttggg aagaaatgat gcatgattta ggcttgaagg atgaataatt tgtataaatt
    75721 agttccaaca agacgtttca tcaagcaatt gaaaaaattg gaccgttata cgcagaagct
    75781 aattacaaac tatttacaaa tcaatgtttt ggaagaccca agacgacacg gaaaggcttt
    75841 ggttggtaat cgcgttggtc aatggcgcta tagaattggt aattatcgag ttatcgtaca
    75901 aattgtagat gatgaattag ttgttgctac tctagaagtt ggtcatcgga gagatattta
    75961 ttgaattaaa gctgagtaat aacaatatag aaagtaagga gagtaaaaat ttgaagaaaa
    76021 aatggttttt tgcagattat tatgacacaa caattatttt acttgcttta atctctgtta
    76081 ttctggtatt acttggattt gctgagatga ttgatttgga caatccgcct tatagtatta
    76141 ttgatttagt aatctggggt gtttttgtaa ttgattatag ttggcgcttt tttacgacta
    76201 aaagaaaatg gcgctttatt cttgaaaata tttttgattt attggctatt ctccctttaa
    76261 atgctatttt cacagttttt cgattagggc gtatctttcg tttagctaaa ctaacaaaat
    76321 tactgaaact gactcgttta cttagaataa ttggacttac aggtaaatta gaaagaaaaa
    76381 ttagtagatt cttacggaca aatggcctga tttatatctt gtatgttaat atctttattg
    76441 ttctagtagg gagttcgatt ttatccgttg ttgaagaaaa atccttctca gatagtcttt
    76501 ggtgggctct tgtgacagta actactgttg gttatggtga tattgttcca gtttcccttt
    76561 ttgggaaatg gctagcagtt ttactgatgc ttgtcggtat tggaacaata ggggtgctaa
    76621 caagtgcttt gacgaacttt tttgtaaagg ataatccaga tgaacagata aaacttgata
    76681 aactcaaaga cgaattatcg agccaaagaa tattaataga gaaacaatct gaaaaaatcg
    76741 aagaactaca ttgaatgata aaagacttag ttgaaaaaat atcataaagg tgagacaaaa
    76801 caaaacttga ttcgaggaga aatcaagtaa gtcttgacac aatagaacgc atattatcag
    76861 gtataaaaac ttgatactat gcgttttata gagaaataaa ataaaatctg aacaaatcaa
    76921 ttaggaattt aaagcatttt ataacaacgt tttagagtga tagggtgcta tttcaacttc
    76981 aacctactat aatacagaaa aaaacaactc cctgatgatt caaggagttg tctatagtta
    77041 aattagtttt tagaagcttc ttggaattct ggatttttcc atgcttcgtc aataatagct
    77101 tgcaattctt tagcagatgc ttgcattttt tgagtttctg catcgttcaa tggaatgttt
    77161 actggacgaa cgataccatg tgcaccaaca acagctggtt gaccgataaa gacattctca
    77221 actccgtatt gaccttcttg gaatactgaa agtggaagta ctgcgttttc atcgtcaagg
    77281 attgctttag tgatacgagc aagggctact gcgataccgt agtatgttgc accttttttg
    77341 ttgatgattg tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa ttcagcttct
    77401 tgaacatttt gagtgtcttt aaggaattct tcaaggttta caccagcgat gttagcgtgt
    77461 gaccaaacag cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg cactgaacga
    77521 gcatccacat ccaatttttc agcaagtgct tgacggaaac gagctgagtc aagtgaagta
    77581 cctgaaccga taacgcgttc tttagggaaa ccagagaatt tccaagttga gtaagtcaaa
    77641 acgtcaactg ggttagcagc aacaaggaag atacctttga aaccagattc aacaacttga
    77701 gttacgattg atctgttgat agcaaggttt ttacctacaa ggtcaagacg agtttcacct
    77761 ggtttttgag gtgcacctgc agtgatcaca acaaggtcag cgtctgcaca gtcagagtat
    77821 tgagctgcat agattttttt aggtgaagtg aaggcaaggg cgtgactaag gtcaagcgca
    77881 tcaccaacag ctttttcatg caattgtgga atttcgataa ttccaagctc ttgtgcaatt
    77941 ccttggttaa caagtgcaaa agcgtaagat gaacctacag caccatcacc gacaaggata
    78001 acttttttgt gttgtttagt tgaagtcatt gttttaaaca tctccttaat tttattaggg
    78061 gattttccct agacaacttc attctatcac ttttaaaaaa ctttgtcacg aatatgcctt
    78121 atagttctcg atgtaaacgt tttagtggtt tagaggctga aatagatggg aatttatggt
    78181 ataatgttgt tacttactaa ttgtgaaatg aggcatttat taatgcagga taaaaattta
    78241 gtgaatgtca atctgacaaa ggagatgaag gcaagtttta tcgactacgc catgagtgtt
    78301 atcgtagcgc gagctcttcc tgatgttcga gatggcttaa aacctgttca ccgtcgcatt
    78361 ctctacggaa tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa atctgctcgt
    78421 attacagggg atgtcatggg taaatatcac ccacacgggg attcctctat ttatgaagcc
    78481 atggtccgta tggctcaatg gtggagctac cgttatatgc ttgtagatgg tcatgggaat
    78541 tttggttcca tggatggaga tagtgctgcc gctcaacgtt ataccgaggc acgtatgagc
    78601 aagattgctc tggaaatgct tcgtgatatc aacaaaaata cagttgattt cgttgataac
    78661 tatgatgcca atgaacggga acccttggtc ttgccagcgc gttttccaaa ccttttggtt
    78721 aatggagcaa ctggtatcgc ggttgggatg gcaaccaata ttccacctca taatctgggt
    78781 gaaaccattg atgcagtgaa gttggtcatg gataatcctg aagtgactac caaggacttg
    78841 atggaagtct tgcctggacc agattttcca actggtgctc ttgtcatggg gaaatcaggt
    78901 atccataagg cttatgaaac aggtaaaggt tcgattgtcc tacgttctcg tacagagatt
    78961 gaaacgacta agactggtcg tgagcgtatc gttgtaacag aatttcctta catggtcaat
    79021 aaaaccaagg tgcatgagca tattgttcgc ttggttcagg aaaaacgcat tgagggtatc
    79081 acagcagtac gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga agtcaagcgc
    79141 gacgcctcag ccaatgttat tctcaataac ctcttcaaaa tgacccaaat gcaaaccaat
    79201 tttggtttca atatgctcgc tatccaaaat ggtataccga aaattttgtc tcttcgtcag
    79261 attttggatg cttatatcga gcaccaaaaa gaagtggttg ttcgtcgtac acgttttgat
    79321 aaggaaaaag cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc gctagaccat
    79381 atcgacgaag tgattcgtat catccgtgct agtgaaacgg atgcggaagc tcaagctgag
    79441 ttgatgagca agtttaagct ttctgaacgt caaagtcaag ctatccttga tatgcgtctt
    79501 cgtcgtttga caggtttgga acgcgataag attcaatctg agtatgatga cctcttggct
    79561 ctgattgcgg atttagcaga tattcttgct aagcctgaac gtgtttctca aattatcaaa
    79621 gacgaattgg atgaagttaa acgtaaattt tctgataaac gccgtacaga gttgatggtt
    79681 ggacaggtct tgagtctcga ggatgaggac ttgattgaag aatcggatgt cttgattacc
    79741 ctttctaaca gaggctacat taagcgtttg gatcaggacg agttcactgc tcaaaaacgt
    79801 gggggtcgtg gtgtccaagg aacgggagtg aaagatgatg actttgttcg tgagttagtg
    79861 tcaactagta cccatgatca tctgctcttc ttcacaaaca agggacgtgt ctatcgtctt
    79921 aaaggttatg aaattcctga gtatggtcgg actgccaaag ggctaccagt agtcaatctc
    79981 ttgaaattgg atgaagacga aagtattcag acggttatca atgttgagtc tgatcgcagt
    80041 gatgatgctt atctcttctt tacaacccgt cacggtattg tgaagagaac cagtgttaag
    80101 gagtttgcca atattcgtca aaatggtctc aaagcgctga atttaaagga tgaagatgag
    80161 ttaatcaatg tcttgttggc agaaggagat atggatatta tcattggtac caagtttggt
    80221 tatgcagttc gctttaatca atcagccgtt cgtggtatga gccgtatcgc caccggtgtg
    80281 aaaggtgtta accttcgtga aggagacaca gttgttggtg ccagcttgat tactgatcaa
    80341 gatgaggttc ttattatcac agaaaaagga tatggtaagc gtacagtcgc tactgaatac
    80401 ccaacaaaag gtcgtggtgg taagggaatg cagacagcta aaattaccga aaaaaatggc
    80461 ttgctggccg gtcttatgac tgttcaaggg gatgaggatt tgatgattat cactgataca
    80521 ggtgtcatga ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc aactatggga
    80581 gttaaagtaa tgcgcctgga tcaagatgct cagatagtga ctttcacaac ggttgcggtg
    80641 gcagaaaaag aagaagttgg gacagaaaac gaaacagaag gtgaagcata atgtctcaaa
    80701 aaaataataa aaagaaaaac aagcgaaaaa atctgctgac aaatatccta gcaggatttc
    80761 tgatattact gtcactggct ttgattttta atactcaaat tcgaaatatt ttcatagtct
    80821 ggaataccaa taagtatcaa gttagccagg tatcaaaaga aaaattagaa gaaaatcagg
    80881 atacagaagg caattttgac tttgattctg tcaaagctat ctcttcggag actgttctaa
    80941 cttctcaatg ggatgctcaa aaattaccag ttattggggg aattgcaatt cctgaattgg
    81001 aaatgaattt gccgattttt aaaggacttg ataatgttaa tctcttctac ggagctggta
    81061 caatgaaacg cgagcaagta atgggagaag gaaattatag tctagctagt caccatattt
    81121 ttggtgttga taatgctaat aaaatgttat tttctccttt agataatgct aaaaatggca
    81181 tgaagattta tctaaccgat aaaaataaag tttatactta tgaaatacgt gaagtcaaac
    81241 gtgtgacacc ggatcgtgtt gatgaagttg atgatagaga tggggtcaat gaaatcacat
    81301 tagtaacctg tgaagacctt gctgctacag aacgtattat tgtcaaaggt gatttgaaag
    81361 aaacaaaaga ttattcacaa acatctgatg aaatcctaac agctttcaat caaccatata
    81421 aacaatttta ttaatacaaa tcagtgaaat catggatttc actgattttt taagattttc
    81481 ataaaaatat agtaaaatga aataagaata ggacgaatcg ttcaggacag tcaaatcgat
    81541 ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatctac tataaacttt
    81601 tatgaaatac agaaaacgct tcctaaaacc taaagtttgt gatataatta tcaagaaaaa
    81661 agatttagga gtttattatg gtttcttcag aatttatctc aaagattgaa tttgcttgca
    81721 ataagaaaga aagtctttat agtcaaagca aatttaagta tgcgattcgt tcgatgttcg
    81781 caggtgcatt tttaaccttc agtactgctg caggtgcagt tggggctgac ttgattaata
    81841 aaattgcatc aggtagtgga cgcttcctct ttccattcgt ttttgcttgg ggcttggcct
    81901 acattgtttt tttgaatgcc gagttggtca cttcaaacat gatgttcttg actgctggta
    81961 gtttcttaaa aaaaatctct tggagaaaaa cagctgagat tttactatac tgtaccttgt
    82021 tcaaccttat cggagccttg atagcagggt ggggctttgc tcattcggca gcctatgcga
    82081 atctgacaca cgatagtttc atctcaggtg ttgttgagat gaagttaggt cgctcaaatg
    82141 aattggtctt gcttgaggcg attttggcaa atattttcgt aaatattgcg attctgtcat
    82201 ttattttggt caaagatggt ggtgccaaac tttggcttgt gttgtcagct atttacatgt
    82261 ttgtattctt aacaaacgag cacattgcgg cgaactttgc ttctttcgcg attgtgaaat
    82321 tcagtgttgc tgcggattca attgccaact tcggtgttgg aaatatgctt cgccactggg
    82381 gtgtaacttt catcggaaac tttatcggag gaggcctctt gatgggtctt ccatatgcct
    82441 tcctcaataa aaacgaagat acttatgtag attaagaaaa tgagcacgat tgagtcgtgc
    82501 ttttttcatt ttcaaaataa ggtaatagct atttcttata tcaaaatata gaaaactgat
    82561 atttgtaaac tataactcaa ggtgctacaa tatccttaat aaaataatat ggaggttacc
    82621 ttatgactcg tgattttaaa tttgaaactc tacaactaca tgctgttcaa gttgtggctc
    82681 cagctactaa gtctcgtgca gtgccgattt atcaaacaac attttttgtt tttgatgaca
    82741 cgtaggaagg tgccgatatg tttgccttga ggaaaccagg gaacatttat actcgtatca
    82801 ccaatcctac aacagctgcc cttgaaggtg gtgttgaagc gctagcaaca gcatcaggta
    82861 tgactgcagt gacttatact attttggcgc ttgtccatgc tggtgaccat gtagtggctg
    82921 cttcgactat ttacggtgga accttcaatc ttttgaaaga accccttcct cgttatggta
    82981 tcacaacaac ctttgtcgat attgataatt tggaggaagt agaagcagct atcaaagaca
    83041 ataccaagct tgtcttgatt gaaaccttgg gtaactcctt gattaatatt ccagacctgg
    83101 aaaaactggc agagattgct cataaacatc aaatcccact tgtgtcagac aatacttttg
    83161 caacacctta tttgattaac gtcttctctc atggcgttga cattgccatt cactctgcga
    83221 ctaagtttat cggtgggcat ggtacaacta ttggaggaat aattgtcgat agtggtcgtt
    83281 ttgactggac ggcttcaggg aaattccctc aatttgttga cgagggtcca agctgccaca
    83341 atttgagtta tactcgtgat gtgggtgcag cagcctttat tatagctgtt cgagttcaat
    83401 tgcttcgtga tacaggtgca gccttgtcac cattcaatgc tttcctcttg ctacaaagac
    83461 ttgaaaccct ttcacttcgt gtggaacgcc atgtgcaaaa tgctgagaca attgttgatt
    83521 ttcttgtcaa ccatcctaag gtagaaaagg taaattatcc aaaacttgca gatagtcctt
    83581 attatgcctt ggctgagaaa tacttgccaa aaggtgtcgg ttcaatcttt accttccacg
    83641 tcaaaggtga cgaggaagaa gcacgcaagg tcattgataa tttagaaatc ttttctgacc
    83701 ttgcaaacgc ggcagatgct aaatcgcttg ttgtccatcc agcaacaacc actcacggtc
    83761 aattgtcaga aaaagaccta gaagcagcag gtgtcacacc aaactaaatt cgtttgtcaa
    83821 tcggtcttga aaatgtagaa gatttgattg aagacttgcg cttggccttg gaaaaaattt
    83881 aaagtaaaag aagataaaca gtgggcttcg actcactgtt tttgattttc cctcaggcat
    83941 gatataatgg ttaaagaagt ctagaaagag gaacgatatg aacgaaatca aatgtcccaa
    84001 ctgtggggaa gtctttacag taaatgagag tcagtatgcc gaactcttgt cccaagtgag
    84061 aacggcagag tttgataagg aactacacga taggatgaag caggaactgg ccttggctga
    84121 gcaaaaggcc atgaatgagc aacagactaa actggctcag aaggatcaag aaattgcgca
    84181 attacagagt cagatccaaa actttgatac agaaaaagaa ttggccaaga aagaagttga
    84241 acagacaagc catcaggctc tcttggctaa ggacaaggaa gtacagctct tagaaaatca
    84301 gttggctacc ttgcgtttgg agcatgaaaa tcaactacaa aagacccttt ctgacctaga
    84361 aaaagaacgg gatcaggtta aaaaccaact acttttgcag gaaaaggaaa atgaattatc
    84421 tttggcttct gttaagcaaa actacgaagc ccagctcaag gcagctagtg aacaagtcga
    84481 gttttataag aattttaagg ctcaacaatc tacaaaagcg attggggaaa gcctagaaca
    84541 gtatgcagag agtgagttta acaaggttcg tagtttcgcc tttccaaatg cttactttga
    84601 gaaggataac aaggtctctt cgcgtgggtc taaaggggac tttatcttcc gtgagtgtga
    84661 tgaaaatgga gttgaaatca tttctatcat gtttgagatg aaaaacgaag cagacggaac
    84721 agagaagaag cacaagaatg cagattttta caaggaattg gacaaggacc gtcgggagaa
    84781 gaactgtgag tatgccgttt tggtgaccat gcttgaggcc gataatgact actttaacac
    84841 agggattgtt gacgtcagcc acgagtatga aaaaatgtat gttgttcgtc ctcaattctt
    84901 tatccagttg attggtctct tacgtaatgc ggcgctaaat tccctaaaat acaagcagga
    84961 gttggccttg gttcgcgagc aaaatattga cattacgcat tttgaggaag acttggatgc
    85021 ctttaagcta gcttttgcta agaactataa ttcagcttcg actaactttg gaaaagctat
    85081 tgatgaaatc gacaaggcca tcaaacgcat ggaagaggtt aagaaattcc tgactacatc
    85141 tgaaaaccaa ctccgtctag ctaacaacaa attggaagat gtctctgtta aaaaattgac
    85201 ccggaaaaat ccaacaatga aagcgaagtt cgaagcattg aagggggagt agaaagcaaa
    85261 aatgaacggt attatcaact taaaaaaaga agcaggaatg acctcgcatg atgcggtttt
    85321 taaactgcgt aagattttgg gaaccaagaa aattggtcat ggcggaacct tggatccgga
    85381 tgtggtgggt gttttgccga ttgcggttgg caaggcgaca cgcatggtcg agtttatgca
    85441 ggacgagggt aagatctatg agggggaaat cactctgggc tattccacga cgactgagga
    85501 tgctagtggg gaagtggtcg cagaaacccc tgttttgtct cccttggatg aaaagcttgt
    85561 tgatgaagcg attgctagct tgactgggcc tattacccag attcccccta tgtattcggc
    85621 agttaaggtt aatggtcgca agctctatga gtatgcgcgt gctggtcagg aagtggagcg
    85681 tccagaacgt caggtgacca tttatcaatt tgagcgaaca agtccgattt cttatgatgg
    85741 ccaacttgcc cgattcactt ttcgtgtaaa atgcagtaaa gggacttaca tccgtacttt
    85801 gtcagttgat ttgggtgaaa agcttggtta tgcggctcat atgtcccatt tgactcgtac
    85861 tagtgctgct ggcttacaat tagaagatgc tcttaccttg gaggaaattg ctgaaaaagt
    85921 agaggctggg caattagatt ttctccatcc tttagagatt gggacaggtg accttgtcaa
    85981 agttttccta actccagaag atgctacaga agttcgcttt ggtcgtttta ttgagctaga
    86041 ccaaacggac aaagaactgg ctgcctttga agatgataaa ttgttagcca ttctagaaaa
    86101 acggggcaat ctctataagc caaggaaggt ttttagctag atcgtttagg aataaaaatc
    86161 gggtgataga taacaattgc ttgataaaac cccatactaa tagtagaatg gttttgggaa
    86221 ttataatatt ccaattgttg cgagttgtag gtactcaaat aatctatata gaaatttaga
    86281 ggtgtgaaat gaagcaattt aaaattcttt cagataaata tttagagtcc attacaggtt
    86341 ctggtgggaa cttaggccca ggatttggtg tgataattcc atgatgcgaa atgagtttcg
    86401 agaaagggtg gagcaacttc ttcaacaaaa agaaataaat gaaaatagtg agttgagtca
    86461 cctgtttcgt cttgctatac aaaatttaga cagaaatgaa aaataccaat cggtcatggc
    86521 caatttgagt caagggttgt cactttacct catgacgcat cattaccagg cacctaagtc
    86581 tgtcattgat tttggtttat ggattgccaa agcttctagc caggaaagag ggagactggc
    86641 tttcttgcag atgcttgctc aaaccctaca gggctttcgt taaaactgtc gaacatcaga
    86701 gggaagactc tggtgttttt tgctgatgag actataaatt ttgtaaaaaa tgtgatagaa
    86761 tagacgacgg ataaaataac ggaggatagc atgcaaaata gaccaatcat tattggagtg
    86821 acaggtggtt ctggtggtgg taaaaccagt gtttcaagag ccattttatc gcattttcct
    86881 gatgaaaaga tttccatgat tgagcatgat tcatactaca aggatcagtc tcatttgacc
    86941 tttgaagagc gtgtcaaaac caactatgac catccttttg cctttgatac agacttgatg
    87001 atcgagcaga ttaaggaatt gttggcaggg cgtccggtgg acatcccgac ctacgactat
    87061 acagagcata cacggagtag caagacctat cgtcaggagc ctcaagatgt ctttatcgtt
    87121 gagggcattt tggtcttgga ggacaagcgt ctgcgcgatt tgatggatat caagattttt
    87181 gtggatacgg atgacgatgt gcgcattatt cgtcgtatca agcgtgatat ggaggagcgt
    87241 ggtcgtagcc ttgatagcgt tattaaccag tacttaggtg tggtcaaacc aatgtaccac
    87301 cagtttatcg agtcaactaa gcgttatgct gatatcgtca ttcctgaagg ggttagcaat
    87361 accgtggcta tcgacctgtt gacgaccaag attgcaaaga ttttggaaga agctcgaaac
    87421 agcaaataat cacatgtgga ggccttgcct cctttttcta tttttccctc ataatggtac
    87481 ataaatggag atttttaggc atatttttgg tataataata cccataaaag agcaagtaaa
    87541 tgaatagtag gtggagatgg aaaagtattt atcggtaaca actttgacca aatatctgaa
    87601 aatgaaattc gataaagacc catacttgga acgggtctat ttaactggtc aagtttccaa
    87661 ctttcgtaaa cgacctactc accaatattt ctccctaaag gatgaccatg cagttattca
    87721 agcgaccatc tggtctggga tttatcagaa attagggttt gacctggaag aaggaatgaa
    87781 gatcaatgtg attgggcgtg tacaggtcta tgaaccaagt ggtagctact ccatcatcat
    87841 tgaaaaagct gagcctgatg gggttggggc gcttgcgatt cagtttgaac aacttaagaa
    87901 aaaattgaca gaagaaggcc tgtttcaaga acgcttcaag caagctctac cccaattttc
    87961 taagagaatt ggggtagtaa ccagccgtag tggagccgtt attcgagata ttatcacgac
    88021 cgtcagcagg cgattcccag gtgttgacat ccttctttat cctaccaagg ttcaaggtga
    88081 aggggctgcg gaggaaattg ctagaaatat tgcgcgtgct aatcaacggg acgatttgga
    88141 tttgctcatt attggtcgtg gaggtggttc tattgaggat ctctgggcct ttaacgaaga
    88201 aattgtggta cgagctattt ttgaatctcg tttgccagtt atctctagtg tggggcatga
    88261 gacggatgtg accttggcag attttgtggc agatcgacgc gctgcaacgc caacagcggc
    88321 ggctgaactg gcaacacctg tgaccaagtt ggatgtatta actcatttgc aaaatcagga
    88381 aaaacggatg gcaacggcag tccgaaatgt tctatctaag aaacaagagg ctttgaaaaa
    88441 atgcagtcag tctgttatct ttagacaacc tgagcgcttg tatgacggtt atttgcaacg
    88501 cttggaccaa ctgcaactgc gtttgaaaca aagtttgcga actcggattt ctgataacaa
    88561 acaattagtt caagcaagaa ctcatcaatt agtacaatta tcacctgtta ccaaaatcca
    88621 acgctatcaa gaccgtttag gacagttgga caagctctta ggtagccaaa tggcgttagt
    88681 ttatgacgcc aaggttgctg aggccaagcg actttcggaa gctttgctca tgttggatac
    88741 tagccgaatc gtggcgcgtg gttatgctat tgtcaaaaaa gaagagtccg ttgtagattc
    88801 ggttgagagt ttgaagaaaa aagaccaagt aacgcttttg atgcgagatg gtcaagtaga
    88861 attagaggtt aaagatgtca aaacaaaaga aatttgagga aaatctagca gaactggaaa
    88921 ccattgtcca aagtttggaa aatggtgaaa ttgctctgga agatgcgatt actgcctttc
    88981 aaaagggcat ggtcttgtca aaagagctcc aagctacgct ggacaaggct gaaaagacct
    89041 tggtcaaggt catgcaagaa gacggaacag aaagtgattt tgaatgaaaa agcaagaaaa
    89101 attagctctt gtcgagtcgg ctttggaaga tttttatgga gaccagcagt ttgcctctag
    89161 tttacgggag tctgttctct attctattca tgctggtggc aagcgtattc ggccttttct
    89221 cttgttagaa gttctggaag ccttgcaggt tgccatcaaa cctgctcacg cgcaggtagc
    89281 tactgccttg gagatgattc atacagggag cttgattcac gatgaccttc ctgctatgga
    89341 tgatgacgat tatcgaagag ggcggttaac caatcacaag aaattcggtg aagctatggc
    89401 cattttggct ggagatgcct tattcttaga cccatatgcc ttgattgcgc aggcagattt
    89461 gccaagtcag atcaaggtgg acttgattgc caacttatcc cttgcttcag gtagtctggg
    89521 tatggtggca gggcaagttt tggatatgga gggcgaacac cagcacttgt ctctggaaga
    89581 acttcagact attcatgcca ataagactgg gaagttacta gcctatccct tccaagcggc
    89641 agctattata gctgaattgt cacctgaaat gcaggtgaag ctgaaaactg tgggtgaatt
    89701 gattggactt gcttttcaag tcagagatga tgtactggat gtgacagcta gttttgagga
    89761 aatcggcaag acacctcaaa aggatctgca ggcagaaaaa tcaacctatc ctgccttgtt
    89821 gggcttggaa gagtccattg ccttttgtaa ccaaaccctg gatcaagcta atgaaaaatt
    89881 agaagaaatt gcccagcagc ttccctttga aacagaatcg attgtaagtg tagtagaaag
    89941 tttgagaatc aatggctaag gaaagagtgg atgtactagc ttataaacag gggttgtttg
    90001 aaacgagaga gcaggccaag cgaggtgtga tggctggcct agtcgtagca gtccttaatg
    90061 gagaacggtt tgacaagcca ggagagaaaa ttccagatga caccgaatta aaactcaagg
    90121 gggagaaact caagtatgtc agccgtggtg gtttgaaact ggaaaaggcc ttgcaggtct
    90181 ttgatttgtc ggtggatggc gcgactacga ttgatatcgg ggcctctact ggaggtttta
    90241 ccgatgtcat gctacagaat agtgccaagt tggtctttgc agttgatgtt ggtaccaatc
    90301 agttggcttg gaaattacgc caagacccac gagttgtcag catggagcag ttcaatttcc
    90361 gctatgctga aaagactgat ttcgagcagg agccgagctt tgccagtatt gatgtgagtt
    90421 tcatttccct tagtctgatt ttgccagcct tgcaccgtgt cttggctgat caaggtcagg
    90481 tggtagcact tgtcaaacct cagtttgagg caggacgtga gcatattggg aaaaatggaa
    90541 tcattcgaga tgctaagatt catcagaatg tccttgaatc tgtaacagct atggcagtag
    90601 aggcaggttt ttcagtcctt ggcttggact tttctcccat ccaaggtgga catggaaata
    90661 ttgaattttt agcgtatttg aaaaaagaaa agtcagcaag caatcagatt cttgctgaga
    90721 ttaaagaagc agtagagagg gcgcatagtc aatttaaaaa tgaataaaaa agaaagactt
    90781 gaaaaaatta gaagattggt gacagattat caaatcggca cgcaagaaga aattgtagaa
    90841 catttgaaag aagcaggtat cactgccact caggcgacgg tatcccgaga tatcaaagag
    90901 ttaggtattg tcaaaattcc tttgagagac aacacctatg tctacgaatt accaaaatca
    90961 atcgtaaaaa gtctgcaact ggctgaagat aatatcgaat cggctgaatt gatggataag
    91021 atgatcaatc tccaagttat tccaggaaat acggcttttg taaaagctca gttaatcgag
    91081 acttttgcag acaagatttt tagctgtttg actgatgata gctcgatttt agtcattgcc
    91141 agaagtggaa gtctagcaga ggaaatcttt gaacaagtaa aaaattggta ggtctatatg
    91201 ttacttgaaa tttctataaa aaactttgcc attattgagg ctatttccct caattttgaa
    91261 aaggggatga ctgtcctgac tggtgaaacg ggtgcaggga agtcgattat cattgatgcc
    91321 atgaatatga tgttgggagc tcgtgcgacg acagatgtta ttcgtcatgg tgcaccaaag
    91381 gcagagattg aggggctttt ctcagttgag aatagtcgtc ttttacagga aatttttgat
    91441 gagcaaggtt tagaattagg tgatgaaatt atcatccgtc gggaaatctt gcaaaatggt
    91501 cgtagtatca gccgtgtaaa tggtcagatg gttaatctgt ctgttttgcg agctattggg
    91561 caacatcttg tagatattca tggtcagcat gaccatgagg agttaatgcg tccccaactg
    91621 catatccaga tgttggatga atttggtgat gccgcttttt gggacttgaa agaaacctat
    91681 caaacgagtt ttgatgccta tcggaaaatg cgtaagcagg ttctggaagt caagaaaaac
    91741 caacaggaac acaaggcacg tattgaaatg ttggaatttc aaatggcaga gattgaggca
    91801 gcaaacttgc aggctggaga agacttggct ctcaatcaag agcgagataa actcctcaac
    91861 cacaaaaata ttgcggatac actgaccaat gcctacagta tgttggacaa tgaagatttt
    91921 tcaagtctgg ccaatgttcg ttcagctatg aatgacatgg aaagtgtcga agagtatgat
    91981 cctgaatacc gtgaaatttc aagctctctg tctgagacct actatgtttt agaagacatt
    92041 agcaaacgtt tggaagctat cattgaggac cttgattttg atggcaatcg cctgatgcag
    92101 gttgagaatc gtttggacct ccttcatact attactcgta agtatggtgg gactgttgat
    92161 gatgttttgc tttattttgc caagattacg gaagaataca atctcttgac aggcaataat
    92221 ctttcgtctg aggacatgga agcagagctt aagaagttgg aagtcaatct tgtcaatttg
    92281 gcaggtcaac ttgcttctgc tcgtcataat ttggctcagc aactcgaagc tgacattaaa
    92341 caagaactgc aagatcttta tatggaaaaa gcccagtttc aggttcgttt tagtaaggga
    92401 aaattcagtc gtgagggaaa tgaaatggtt gagttttata tttcaaccaa ccctggagaa
    92461 gactttaaac ccttggttaa ggttgcttct ggaggggaat tatctcgtct catgttagcc
    92521 attaagtctg ccttttcacg taaagaaggc aagactagca ttgtctttga tgaggtggat
    92581 acgggagttt caggtcgtgt tgctcaagct attgctcaga aaattcataa aattggtcag
    92641 tatggtcagg ttttggctat ctcccatttg ccacaagtaa ttgcgattgc agattatcaa
    92701 ttttttattg agaagattag taatgaccat tcaacggttt cgactgttcg tctcttgaca
    92761 gtcgaagagc gagtggagga agttgccaag atgttggcag gtgatgatgt gacagaagca
    92821 gccctgacgc aagccagaga attgttgaga aacagggaga aataagatga cagattatta
    92881 tgtaattgga gatgttcacg gaaaagctgg gatgctggaa gaccttctta aaacctggga
    92941 tggtcagacc cagttgttct ttctaggtga tttgattgac agaggtgagg atagtcaccg
    93001 tgttcttgaa atggtcaagg acttggtgga caatcaaggg gctatctgtt tgtctggaaa
    93061 ccacgagtat atgtttttga cttggctaga tgacccagaa gaaagttatg accattatcg
    93121 tcgcaatggt ggagatacaa ccattaactc tatcctaggt cgtcccttgg atgcaccagt
    93181 tgatggagta gaagatgcca agcgggttgc cgctgaagcg gcagacttgg tcgaattcat
    93241 tcgtcaaatg ccatttgtag tagagacaga caagtatatc tttgttcacg caggtattga
    93301 tttgaccttg gacgactggc atgaaacaac agattataaa aaagtatggc ttagaaaacc
    93361 attccacgga gctgaaaatc atactggaaa aaccattgtc ttcggtcata caccggtcta
    93421 tggtttgtta cagcaagaac gcggtacatc tgagctttgg actacagaag atggcaagat
    93481 tggaatggat ggaggagctg tttatggtgg tgtccttcac gggattgtct ttacagacca
    93541 aggaatgaca gaacaccact ttatcgaaaa tgacggcttt gtcgctgaag attagtactc
    93601 ctagcagggt atggtcttgt caaaatatca aaaacaattt ataataaata gataccctga
    93661 aaggaagaga atcatgaact tagaagaatt gaaaaaacga caggagaaga tccgtaactt
    93721 ctctattatc gcccatattg accacgggaa atcaactcta gcagaccgca ttttggaaaa
    93781 aacagagacg gtttcaagtc gtgaaatgca ggcccagctt ttggatagca tggatctaga
    93841 gcgggaacgt ggaattacta ttaagttgaa tgccatcgag ttgaattaca ctgcaaaaga
    93901 tggggaaact tatattttcc acttgattga cacaccaggg cacgttgact ttacctatga
    93961 agtttcacgt tcgctagctg cctgtgaggg tgctattttg gtggtcgatg cggctcaagg
    94021 aattgaggct caaactcttg ccaacgttta tctggctttg gataatgatt tggaaatcat
    94081 gcctatcatt aataaaattg acctgccggc tgcagatccg gagcgcgtgc gtacagagat
    94141 tgaagatgtg attggtttgg atgccagtga agcagttttg gcttctgcca aggctggtat
    94201 tgggattgaa gaaatcctcg agcaaattgt agaaaaagta ccagcaccaa cgggtgatgt
    94261 gacggcgcca cttaaggcct tgattttcga ctctgtttac gatgcttacc gtggggttat
    94321 cctccaagta cgtgtcatgg acggagtggt caaacctggt gataagattc agctcatgag
    94381 caatagtaag acctttgatg tggccgaagt cggtattttt acacccaaag cggttggtcg
    94441 tgatttcctt gcgactggtg atgttggtta cattgcggcg tctatcaaga cggttcagga
    94501 tactcgtgtg ggtgataccg ttaccttggc aaccaatcct gcggcagaac cattacatgg
    94561 ttataagcag atgaatccta tggtctttgc gggtctctac ccaatcgaat caaacaagta
    94621 caatgacctg cgtgaagcgc ttgaaaaatt gcaactgaat gatgctagtc ttcagtttga
    94681 accagaaaca tctcaggcac ttggatttgg tttccgttgt ggatttcttg gacttctcca
    94741 tatggatgtt atccaggaac gtttagagcg tgagttcaat attgacctca tcatgacagc
    94801 tccgtctgtt atttacaaag ttaatttgac cgacggtgag tctatggatg tgtctaaccc
    94861 atctgagttt ccagacccaa ctaagattgc gaccattgaa gagccttatg tcaaggcgca
    94921 aatcatggta ccacaggagt tcgtcggagc agtaatggag ctagctcagc gtaagcgtgg
    94981 ggactttgtg actatggact atattgatga taaccgtgtc aatgttatct atcaaattcc
    95041 tcttgctgaa attgtctttg acttctttga taaacttaag tcttcgacac gtggttatgc
    95101 aagctttgac tacgaattgt cagaatatcg cccatctaag ctggtgaaaa tggatattct
    95161 tctcaatgga gataaggtgg atgccctcag ctttatcgtt cacaaggact ttgcctacga
    95221 acgtgggaaa ctcatcgttg ataaactcaa gaaaatcatc cctcgccaac aatttgaagt
    95281 tccaatccaa gcggctattg gacacaagat tgtcgctcgt actgatatca aggcccttcg
    95341 taagaacgta cttgctaaat gttatggtgg tgacgtttct cgtaagcgta aactccttga
    95401 aaaacaaaaa gctggtaaga aacgcatgaa atccatcgga tcagttgaag ttccgcaaga
    95461 agccttcctc agcgtcttga gtatggatga agaataagtt atcagaaatg cctttccttg
    95521 ttcacaggaa atttatataa gaatcaatag taaagggctc tttgtcaact gtagtgggtt
    95581 gaagaaaagc taagcttgag aaaggacaaa tttcgtcctt tcttttttga tgttcagagc
    95641 gataaaaatc cgttttttga agttttcaaa gttccgaaaa ccaaaggcat tgcgcttgat
    95701 aagtttgatg agattattgg tcgcttccag tttggcatta gaatagtgta gttgaagggc
    95761 gttgataatc ttttctttat ctttgaggaa ggttttaaag acagtctgaa aaagaggatg
    95821 aacctgctta agattgtcct caataagtcc gaaaaatttc tccgattcct tattctgaaa
    95881 gtgaaacagc aagagttgat agagct
//
LOCUS       DAVDFK010000004        94740 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.04, whole genome shotgun sequence.
ACCESSION   DAVDFK010000004 DAVDFK010000000
VERSION     DAVDFK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 94740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.04"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..316
                     /locus_tag="VUR04_000303"
     CDS             <1..316
                     /locus_tag="VUR04_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5340268.1"
                     /translation="DVFSEEHIYYAHPYASWERGTNENHNRLIHRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRNRFKFCRSFKYPARRCS
                     WC"
     gene            288..932
                     /locus_tag="VUR04_000304"
     CDS             288..932
                     /locus_tag="VUR04_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET5340269.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(974..2962)
                     /locus_tag="VUR04_000305"
     CDS             complement(974..2962)
                     /locus_tag="VUR04_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340270.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTAIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2964..3722)
                     /locus_tag="VUR04_000306"
     CDS             complement(2964..3722)
                     /locus_tag="VUR04_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340271.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            complement(4702..4965)
                     /locus_tag="VUR04_000307"
     CDS             complement(4702..4965)
                     /locus_tag="VUR04_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET5340272.1"
                     /translation="MISKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEG"
     gene            complement(5024..5473)
                     /locus_tag="VUR04_000308"
     CDS             complement(5024..5473)
                     /locus_tag="VUR04_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET5340273.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            complement(5460..7589)
                     /locus_tag="VUR04_000309"
     CDS             complement(5460..7589)
                     /locus_tag="VUR04_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET5340274.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LAINRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLALNETD"
     gene            8001..8906
                     /locus_tag="VUR04_000310"
     CDS             8001..8906
                     /locus_tag="VUR04_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET5340275.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            8903..9718
                     /locus_tag="VUR04_000311"
     CDS             8903..9718
                     /locus_tag="VUR04_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET5340276.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(9848..10564)
                     /locus_tag="VUR04_000312"
     CDS             complement(9848..10564)
                     /locus_tag="VUR04_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5340277.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEALLRLRRKIQAFKREVGDTLFISPRYPNKATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10568..10878)
                     /locus_tag="VUR04_000313"
                     /pseudo
     CDS             complement(10568..10878)
                     /locus_tag="VUR04_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11021..11365
                     /locus_tag="VUR04_000314"
                     /pseudo
     CDS             11021..11365
                     /locus_tag="VUR04_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(11511..12383)
                     /locus_tag="VUR04_000315"
     CDS             complement(11511..12383)
                     /locus_tag="VUR04_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET5340278.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            13231..13456
                     /locus_tag="VUR04_000316"
                     /pseudo
     CDS             13231..13456
                     /locus_tag="VUR04_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(14036..15541)
                     /gene="pyk"
                     /locus_tag="VUR04_000317"
     CDS             complement(14036..15541)
                     /gene="pyk"
                     /locus_tag="VUR04_000317"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET5340279.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIVLNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(15600..16607)
                     /gene="pfkA"
                     /locus_tag="VUR04_000318"
     CDS             complement(15600..16607)
                     /gene="pfkA"
                     /locus_tag="VUR04_000318"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET5340280.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAVEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(16689..19790)
                     /locus_tag="VUR04_000319"
     CDS             complement(16689..19790)
                     /locus_tag="VUR04_000319"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET5340281.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKLAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMRELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFLAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKVLGSLFGETIYSWQDSEDWMEQEKFYMEQELLG
                     VGVSKHPLQAIANKAIYPITPISNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            20137..22410
                     /locus_tag="VUR04_000320"
     CDS             20137..22410
                     /locus_tag="VUR04_000320"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET5340282.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTYIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            22427..22897
                     /locus_tag="VUR04_000321"
     CDS             22427..22897
                     /locus_tag="VUR04_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5340283.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(23403..26753)
                     /locus_tag="VUR04_000322"
     CDS             complement(23403..26753)
                     /locus_tag="VUR04_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET5340284.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKSSVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVYILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDRYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(26783..26857)
                     /locus_tag="VUR04_000323"
                     /pseudo
     CDS             complement(26783..26857)
                     /locus_tag="VUR04_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA CCA-pyrophosphorylase"
     gene            complement(26972..27385)
                     /locus_tag="VUR04_000324"
     CDS             complement(26972..27385)
                     /locus_tag="VUR04_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET5340285.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(27382..27618)
                     /locus_tag="VUR04_000325"
     CDS             complement(27382..27618)
                     /locus_tag="VUR04_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET5340286.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(27678..28799)
                     /locus_tag="VUR04_000326"
     CDS             complement(27678..28799)
                     /locus_tag="VUR04_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5340287.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVAQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            complement(28812..30305)
                     /locus_tag="VUR04_000327"
     CDS             complement(28812..30305)
                     /locus_tag="VUR04_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET5340288.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(30813..31979)
                     /locus_tag="VUR04_000328"
     CDS             complement(30813..31979)
                     /locus_tag="VUR04_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET5340289.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPINRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVNKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASEFEPQYCLATSRRANAHYVY
                     SEENLLAKYSQQFKVKKIMPEAFAELQGDYFYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(32037..32732)
                     /locus_tag="VUR04_000329"
     CDS             complement(32037..32732)
                     /locus_tag="VUR04_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET5340290.1"
                     /translation="MHIEHLSHWSGHLNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQKQIPAW
                     FAEWGHDVAHDWE"
     gene            complement(32754..33578)
                     /locus_tag="VUR04_000330"
     CDS             complement(32754..33578)
                     /locus_tag="VUR04_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5340291.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(33715..34929)
                     /gene="thiI"
                     /locus_tag="VUR04_000331"
     CDS             complement(33715..34929)
                     /gene="thiI"
                     /locus_tag="VUR04_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET5340292.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(34938..36080)
                     /locus_tag="VUR04_000332"
     CDS             complement(34938..36080)
                     /locus_tag="VUR04_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5340293.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            complement(36240..36617)
                     /locus_tag="VUR04_000333"
     CDS             complement(36240..36617)
                     /locus_tag="VUR04_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340294.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            complement(36627..38711)
                     /locus_tag="VUR04_000334"
     CDS             complement(36627..38711)
                     /locus_tag="VUR04_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5340295.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            38874..39302
                     /locus_tag="VUR04_000335"
     CDS             38874..39302
                     /locus_tag="VUR04_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340296.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNKNTKKEPTTSQTTTFVKEIQKEPPQENTTPNKENNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            complement(39346..41571)
                     /locus_tag="VUR04_000336"
     CDS             complement(39346..41571)
                     /locus_tag="VUR04_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET5340297.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLMGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(41735..43687)
                     /locus_tag="VUR04_000337"
     CDS             complement(41735..43687)
                     /locus_tag="VUR04_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5340298.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLTGHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     VATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(43684..44595)
                     /gene="pfkB"
                     /locus_tag="VUR04_000338"
     CDS             complement(43684..44595)
                     /gene="pfkB"
                     /locus_tag="VUR04_000338"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET5340299.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVKLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(44592..45332)
                     /locus_tag="VUR04_000339"
     CDS             complement(44592..45332)
                     /locus_tag="VUR04_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5340300.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGINGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            45494..45581
                     /locus_tag="VUR04_000340"
     tRNA            45494..45581
                     /locus_tag="VUR04_000340"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45528..45530,aa:Ser,seq:gga)
     gene            complement(45761..46108)
                     /gene="ssrA"
                     /locus_tag="VUR04_000341"
     tmRNA           complement(45761..46108)
                     /gene="ssrA"
                     /locus_tag="VUR04_000341"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(46753..47862)
                     /locus_tag="VUR04_000342"
     CDS             complement(46753..47862)
                     /locus_tag="VUR04_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET5340301.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            47965..49206
                     /locus_tag="VUR04_000343"
     CDS             47965..49206
                     /locus_tag="VUR04_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET5340302.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(49405..50817)
                     /gene="sufB"
                     /locus_tag="VUR04_000344"
     CDS             complement(49405..50817)
                     /gene="sufB"
                     /locus_tag="VUR04_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET5340303.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(50871..51311)
                     /locus_tag="VUR04_000345"
     CDS             complement(50871..51311)
                     /locus_tag="VUR04_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET5340304.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(51298..52524)
                     /locus_tag="VUR04_000346"
     CDS             complement(51298..52524)
                     /locus_tag="VUR04_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5340305.1"
                     /translation="MLDVEAIRKDFPILNQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(52535..53797)
                     /gene="sufD"
                     /locus_tag="VUR04_000347"
     CDS             complement(52535..53797)
                     /gene="sufD"
                     /locus_tag="VUR04_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET5340306.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(53825..54595)
                     /gene="sufC"
                     /locus_tag="VUR04_000348"
     CDS             complement(53825..54595)
                     /gene="sufC"
                     /locus_tag="VUR04_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET5340307.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(54745..54939)
                     /locus_tag="VUR04_000349"
     CDS             complement(54745..54939)
                     /locus_tag="VUR04_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET5340308.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(54967..56622)
                     /gene="dnaX"
                     /locus_tag="VUR04_000350"
     CDS             complement(54967..56622)
                     /gene="dnaX"
                     /locus_tag="VUR04_000350"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET5340309.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAINCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(56622..57119)
                     /locus_tag="VUR04_000351"
     CDS             complement(56622..57119)
                     /locus_tag="VUR04_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET5340310.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            complement(57205..58407)
                     /gene="rpsA"
                     /locus_tag="VUR04_000352"
     CDS             complement(57205..58407)
                     /gene="rpsA"
                     /locus_tag="VUR04_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET5340311.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(58569..58640)
                     /locus_tag="VUR04_000353"
     tRNA            complement(58569..58640)
                     /locus_tag="VUR04_000353"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58606..58608),aa:Gln,seq:ttg)
     gene            complement(58650..58730)
                     /locus_tag="VUR04_000354"
     tRNA            complement(58650..58730)
                     /locus_tag="VUR04_000354"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58694..58696),aa:Tyr,seq:gta)
     gene            complement(58780..59010)
                     /locus_tag="VUR04_000355"
     CDS             complement(58780..59010)
                     /locus_tag="VUR04_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET5340312.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKTVEILIENYNLAK"
     gene            complement(59178..59822)
                     /gene="pcp"
                     /locus_tag="VUR04_000356"
     CDS             complement(59178..59822)
                     /gene="pcp"
                     /locus_tag="VUR04_000356"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET5340313.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(59837..60760)
                     /locus_tag="VUR04_000357"
     CDS             complement(59837..60760)
                     /locus_tag="VUR04_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET5340314.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(60757..61446)
                     /locus_tag="VUR04_000358"
     CDS             complement(60757..61446)
                     /locus_tag="VUR04_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET5340315.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(61511..62215)
                     /locus_tag="VUR04_000359"
     CDS             complement(61511..62215)
                     /locus_tag="VUR04_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340316.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(62271..63293)
                     /locus_tag="VUR04_000360"
     CDS             complement(62271..63293)
                     /locus_tag="VUR04_000360"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET5340317.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(63425..65896)
                     /gene="parC"
                     /locus_tag="VUR04_000361"
     CDS             complement(63425..65896)
                     /gene="parC"
                     /locus_tag="VUR04_000361"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET5340318.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(66316..68259)
                     /gene="parE"
                     /locus_tag="VUR04_000362"
     CDS             complement(66316..68259)
                     /gene="parE"
                     /locus_tag="VUR04_000362"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET5340319.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSNWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            68395..69036
                     /gene="plsY"
                     /locus_tag="VUR04_000363"
     CDS             68395..69036
                     /gene="plsY"
                     /locus_tag="VUR04_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET5340320.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(69079..70416)
                     /locus_tag="VUR04_000364"
                     /pseudo
     CDS             complement(69079..70416)
                     /locus_tag="VUR04_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(70501..71457)
                     /locus_tag="VUR04_000365"
     CDS             complement(70501..71457)
                     /locus_tag="VUR04_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340321.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            complement(71460..72518)
                     /locus_tag="VUR04_000366"
     CDS             complement(71460..72518)
                     /locus_tag="VUR04_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340322.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALLHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGSVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            complement(72511..74046)
                     /locus_tag="VUR04_000367"
     CDS             complement(72511..74046)
                     /locus_tag="VUR04_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340323.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPYSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            complement(74190..75242)
                     /locus_tag="VUR04_000368"
     CDS             complement(74190..75242)
                     /locus_tag="VUR04_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET5340324.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNVASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            complement(75332..75721)
                     /locus_tag="VUR04_000369"
     CDS             complement(75332..75721)
                     /locus_tag="VUR04_000369"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET5340325.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            complement(75708..76370)
                     /gene="deoC"
                     /locus_tag="VUR04_000370"
     CDS             complement(75708..76370)
                     /gene="deoC"
                     /locus_tag="VUR04_000370"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET5340326.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            complement(76388..77665)
                     /locus_tag="VUR04_000371"
     CDS             complement(76388..77665)
                     /locus_tag="VUR04_000371"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET5340327.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLSLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            complement(77662..78243)
                     /locus_tag="VUR04_000372"
     CDS             complement(77662..78243)
                     /locus_tag="VUR04_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5340328.1"
                     /translation="MYYAENPDAAHDIYELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            complement(78459..78863)
                     /locus_tag="VUR04_000373"
     CDS             complement(78459..78863)
                     /locus_tag="VUR04_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340329.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            79053..79973
                     /locus_tag="VUR04_000374"
     CDS             79053..79973
                     /locus_tag="VUR04_000374"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET5340330.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            80041..80277
                     /locus_tag="VUR04_000375"
     CDS             80041..80277
                     /locus_tag="VUR04_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET5340331.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            80330..80854
                     /locus_tag="VUR04_000376"
     CDS             80330..80854
                     /locus_tag="VUR04_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET5340332.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRK
                     LDQFLDKKRKSYNS"
     gene            complement(80877..81587)
                     /gene="deoD"
                     /locus_tag="VUR04_000377"
     CDS             complement(80877..81587)
                     /gene="deoD"
                     /locus_tag="VUR04_000377"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET5340333.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVEYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(82245..82757)
                     /locus_tag="VUR04_000378"
     CDS             complement(82245..82757)
                     /locus_tag="VUR04_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET5340334.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(82782..83762)
                     /locus_tag="VUR04_000379"
     CDS             complement(82782..83762)
                     /locus_tag="VUR04_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET5340335.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHT
                     NFQSKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            complement(84238..85047)
                     /locus_tag="VUR04_000380"
     CDS             complement(84238..85047)
                     /locus_tag="VUR04_000380"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET5340336.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(85063..85605)
                     /locus_tag="VUR04_000381"
     CDS             complement(85063..85605)
                     /locus_tag="VUR04_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET5340337.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            complement(85607..86818)
                     /locus_tag="VUR04_000382"
     CDS             complement(85607..86818)
                     /locus_tag="VUR04_000382"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET5340338.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(86832..87515)
                     /gene="rpiA"
                     /locus_tag="VUR04_000383"
     CDS             complement(86832..87515)
                     /gene="rpiA"
                     /locus_tag="VUR04_000383"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET5340339.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(87797..88669)
                     /locus_tag="VUR04_000384"
     CDS             complement(87797..88669)
                     /locus_tag="VUR04_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET5340340.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(88811..89668)
                     /locus_tag="VUR04_000385"
     CDS             complement(88811..89668)
                     /locus_tag="VUR04_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET5340341.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(89822..90556)
                     /locus_tag="VUR04_000386"
     CDS             complement(89822..90556)
                     /locus_tag="VUR04_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5340342.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKDESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLRKVL"
     gene            complement(90556..91239)
                     /locus_tag="VUR04_000387"
     CDS             complement(90556..91239)
                     /locus_tag="VUR04_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5340343.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            91429..91659
                     /locus_tag="VUR04_000388"
     CDS             91429..91659
                     /locus_tag="VUR04_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET5340344.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            91888..94146
                     /locus_tag="VUR04_000389"
     CDS             91888..94146
                     /locus_tag="VUR04_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5340345.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNGL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
     gene            complement(94353..94740)
                     /locus_tag="VUR04_000390"
                     /pseudo
     CDS             complement(94353..94740)
                     /locus_tag="VUR04_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT        28398 a        20724 c        16915 g        28703 t
ORIGIN      
        1 tgatgtattt tctgaggagc acatctatta tgcgcacccc tatgcctctt gggaaagggg
       61 aactaatgag aatcacaaca ggctcattca tagatggtta cctaagggaa ccaagaaaat
      121 gactcccaaa gaagtcgcat tcatcgaaaa gtggattaac aactatccta aaaaatgctt
      181 gaactacaag tcacccagag aagacttctt gatggctaac ttgaacttga aatttagcgt
      241 cagaaacaaa tcacgaaatc gattcaaatt ttgcaggtcg tttaaatatc ctgcgcgcag
      301 gtgttcttgg tgctaacgat ggaattattt ccattgctgg tgtggttatc ggggttgcca
      361 gtgccacgac caatatctgg attatctttt tatcaggatt tgcggctatc ttagctggtg
      421 ccttttcaat ggctggtgga gaatatgtat ccgtttcaac tccaaaagat accgaggaag
      481 ctgccgtttc gcgagaaaaa ctcttgttag accaagatag ggaactagcc aaaaaatccc
      541 tctatgctgc ttatatccaa aatggagaat gcaaaacttc tgcccaactc ttgaccaata
      601 agatctttct taaaaatcca ctcaaggctc tggtagagga aaaatatggg attgagtatg
      661 aagaatttac caatccttgg cacgctgcca tttctagctt cgttgccttt ttccttagaa
      721 gtttgcctcc aatgctgtca gtgaccatat tcccaagtga atatcgcatc cctgctactg
      781 tccttattgt cggtgtggcc cttcttctca ctggttacac tagtgccaga cttggaaagg
      841 atccgactag aacagctatg attcggaacc ttgctattgg tctcttgacc atgggagtta
      901 ccttcctgct cgaacaactt ttcagcattt agaatacaag aaatacctcg attttgaagt
      961 cgaggtatct tttttacatt tgcacaatct tgcgataact tcttgaagta atcatgaaaa
     1021 tcagcacata ggcgatgagg aagatagcgc agatagacaa ggtcacaatc aacatcatag
     1081 tcgtatccag tacaccaatc acttttaaaa tcaggctaag catatggtag gcaaaggcga
     1141 gatgtatgaa ggcaaagagc aaaggaagga agaaaacagt taaaacctgt ttgttgatgg
     1201 tttgcttgat ttgcttttgg tccaaaccga ctttctgcaa gataataaag cgttcacggt
     1261 cttcatagcc ttcagaaatt tgtttgtagt agatgaccag aacagttccg accataaaga
     1321 taatggatag gaaaataccg ataaagaaga caccaccaaa gagggcactc atctgagaac
     1381 tagcatctgc tagattgcta ccataaacat agctaccttc tgtgtctaat tgagcattaa
     1441 attgattgag gtagttttca tactcctcag cgaccttgag ttgttcttct tcgctggcat
     1501 ctacattcat accaccgtaa aactgattat agatagccga atctgggaat tgatccaaaa
     1561 aggcttgtaa atcaggaaca acaaggtaat tgtaatcagt agtcaagata ttaaacttat
     1621 ttggaacatg gttgacaatg aaatctttat taaattcttc tttgacagaa aattgatgat
     1681 catttagagt tagagctttc tgtcctttca gtccgtcatt tttggcaaag agaccgacct
     1741 catttcctga tagagacagt ttttgaccag tcatattttc ataatctttt tggtcaaata
     1801 ccatgaaaac tgtttttggt tggacacggt tttgtccttt ttcaaaaata gttaacttgg
     1861 ttccttcttg attcgcaaca gcaaagtaag tgtaacgaag cacttctttc tctttaatct
     1921 tataaccttt gtcacttgca aactggctca agagtttgtc caaatcttct ttttcaacat
     1981 tttgccctga aaccccaaaa tcatgaggat ttagaacttt tttaaaggat tctgcggaat
     2041 tgaaaatgct tgtcgctgct gacatggtta ccaaaaccat tgttgacaaa atagcgatag
     2101 ttgctagtcc aactgcattt ttcttcatac ggaaaatcaa gttagaaaca gatatgagat
     2161 tattaggttg gtaatagtat ttcttatttt tctttaagat ttgaaggaaa acggtaatcc
     2221 ctgcattgaa caaaagataa gtaccaaaga taaccagtaa aacagctatg aagaaggttg
     2281 ttaaggctgt aagaggatct tttaccgtaa gggcaagata atatccaatc cctaaactta
     2341 tggaaccaag aatagtttgg agaggaagga agcgaccttt tttctctccg ctagctttct
     2401 cacgtgagag ctggagggca ttcatacggg cgattcgaag ggcattcagg aacatgaggc
     2461 ctaggaaaat caaaccgaag acaagaagta ctgtaatgac aactttcatc tggaaggtag
     2521 cgaccagttc caccttcaat ttcatcagtt tgagtaggaa agcgaaaatc aacttgtcaa
     2581 acaaggctcc aataccgatt cctgctccaa cagttagaat cccaaatagc actaactcct
     2641 taaaggtcat actgattaga tggcgcttct ccaagcctaa catgccatat atacccagtt
     2701 ccttggaacg gtttttcatg acaaaactat tggcatagag gacgataatg gctgacgcaa
     2761 gggtaacgac aaacatacca aatccaagtg ttgcttgaat ggcggttcct ccacggattt
     2821 ccgcaatctt tggattgaag gttagggagt aaaagagata ggtgatggtg actgccaaga
     2881 gaacagccag tgcaaaggga tagtagagtt tgcggttttt aatcaagttc gataccgcta
     2941 acttattggt taatcgaaac atactaattc acctcgcttg ccatgacagt caaggtatca
     3001 gagatttctt ggaacatctg acgctctgtc ttctctccac ggtagatttg gttgtaaaga
     3061 atgccgtctt tgataaagag aacacgcttg gccctgctag cagctgctgt tgagtgggtt
     3121 accatgagga tggtttgccc acgctcattg atttcattaa agacatcaag taaggctgca
     3181 gatgacttgg aatcaagggc tcctgttggc tcgtccgcaa ggagaatttc aggttctgtg
     3241 atgatggcgc gggctactgc tacacgctgt ttctgaccac cagaaatctc gtaagggtac
     3301 ttctcttgca attggttgat acccagattt tcagctgtca tcaccaattt cttcatcatc
     3361 tccgttatag gtcttcttga caagacaagc ggaagcaaga tattgtcctt aacagacaga
     3421 gtatctagca agttaaagtc ttggaagaca aatcctagct tttcacgccg gaaactagaa
     3481 gcctgtgaat ttttaatagt tgctgtatca gttccgttta ggtaaacctg cccacgactt
     3541 ggtttatcca gcatagctag gatattgagc agagtggatt taccagaacc agactcaccc
     3601 atgatagcaa cgtagtcacc cttttctacg gtgaagtgaa tatccttgag ggcctctact
     3661 tggttgccct gaaaacgagt tttataaatt ttttgaacgt gttttacatc taaaagtgtc
     3721 atgagaatct cctttcttaa tatcccatca aatgaaatgt agcttgcatc atagtgcatc
     3781 ccagctgaat gcgctcaatt tctttgtgac ttggttttct agttttctta tgtaagattt
     3841 gtttcatgat gttactcctt tgttctttat gagtctagtt tacatcaaaa aaagaccgct
     3901 tgccataacc taaccttaca aaagagactt taatcttaca tttttgtaag attgggggaa
     3961 atataagcaa aattacttag aaaatgattt gatttcctat ttttaaagtt gtaaaatata
     4021 agtatgaaaa ggcttacttt aaaaaggagg aagcgggaac taacatttta gtaaggttac
     4081 ctagataaca tgccattcaa tttaacactt gcaagtcgtt caacctataa ggaaagaagg
     4141 tgcgctttaa tgaaacataa agaacatata ctcatcggat ttctctatct gctctctcca
     4201 ttcatcggtc agctctcagt tgaacacaca ctttatcggt acagaattta ccggcactgc
     4261 ttatgttatt tgctggttat cagttgttat cagcatccac catttttcca aaaatgtatt
     4321 gtctcagcag caaaaataga ttaaaaaatt gcgtttaaat tactgctttt atagtaaaat
     4381 gaaataagaa caggacaaat cgatcaggac agttaaatcg atttctaaca atattttaga
     4441 agtagaggtg tactattcta gttccaatcc actatagttt gtggatgaag ctggcgaaat
     4501 attattaata ctattcaaaa atcaaagtgc aaactatatc aacttcacat tgccgactaa
     4561 attacagcct gcggctggct tcctagtttg cactttgatt tttattgagt ataaaagtaa
     4621 aaaagcttta aatcaagcag tttagactat tgatttaaag ctttttgctt attccaaatc
     4681 ttctgtagaa cctcaccaaa atcagccttc attatcgtca atggcttggg cttctttgcg
     4741 tttgcgtggg cctgttccgt acatttctgc ttcgatttct tccttagtag gcatgataga
     4801 agctaggatg atatagataa tcactccaag tccaaagttt gcgactgtaa aaatggcaaa
     4861 cagaaaacgt acaagggtaa catcaaagtt ccacttgtct gacagacctg ctaaaactcc
     4921 tgaaatcatg cgatttcgtc tcattttata aaacttactg atcatgatat ttcctctttc
     4981 tgctaggtta gacatagtat atcacggata ggctcggctt tcatcagtcc tcaggctgat
     5041 ttactaatag caactttcct cgacaaagtc cacagcgata gcgttgggta tcaatccttc
     5101 gcttgcgctg ataagtttgc tggcaggatt ggcaacgata gagcttgatt ggcttggagt
     5161 tactattggg caaggatggt acaaaccgta atccatccac tgctttcaac agttccttaa
     5221 aatcccgatc cttgtgttga tagcctttcc cttgaaaata gaggtgataa tgacagagtt
     5281 catgtcggac aattttccta aaaacgtcca accccagttc ctgataaacc ttgggattaa
     5341 aatccaaatg cccatctttg gggaaaaatc gcccacctgt cgaacgtaga cgcctattcc
     5401 actggacatg atggataaaa ggtctgccga agtcttctag tgaaacctgc ttgacgtaat
     5461 cagtcagttt catttagagc taggagagac agattaactt tttcacgttc agtatcaatt
     5521 ttcttaaccc aaacgctcac caaatctcca actgccacca cttgactagg gtgtttgata
     5581 aacttgcgac tcatatggga aatatggatg agaccgtcct catgaattcc gatatcaaca
     5641 aaagcaccga aatcaacaac gttacgcacc actccttcta gcttttgtcc aaccactaag
     5701 tccttgatat ctaggacatc ttgacggaga actggagcat caaaggaatc acggaaatct
     5761 cgacctggtt tgagaagatc tgcaatgata tctttaagag tttctggacc aaggtctaac
     5821 tcttgcgcca tttccttgac tgaaagcgac ttgagtttgc tttgggcctc ttcattcaga
     5881 tccttaatgt ccaagcattt gaagagttcc ttaacggcag cgtaattttc tgggtgaact
     5941 cctgtattat caaggatatt gctactttca gggatacgga ggaaaccagc agcctgttca
     6001 aaagccttgg cccccaaacg aggaactttc ttgatttggg agcgtgaagt gatttttccc
     6061 tcttcctcac ggtatttgac gatattttca gaaatggttt tattgagtcc agctacgtgt
     6121 gaaagaagag ctgggctagc tgtattgaca ttgacaccaa cttggttaac cactgtatcg
     6181 acaacaaagt ccagactctc agatagtttc ttctgactga catcgtgttg gtattgaccg
     6241 acaccaattg acttaggatc gattttgacc aattccgcaa gaggatcttg caaacgacgg
     6301 gcgatagaaa tggcagagcg tttttcaacg gtcaagtctg gaaactcctg acgagcaagt
     6361 tcgctggcag aatagacaga agcaccactt tcattaacga taacatagct gacttcaggg
     6421 aaatctttca gaacttccgc tacaaaagct tcactttcac gactggccgt tccatttcca
     6481 atggcaataa tctctacacc gtattgacca attaaatctg ctaaatcttt cttggcttct
     6541 tcgatttgac gagctgatgc tggtttaaca ggataaataa cctgagttgt cagcattttt
     6601 cctgttgcat ccacgacagc tagcttggca cctgtacgaa aggctgggtc aaacccaaga
     6661 accacgcgcc ctttcagtgg agcaaccaag aggagattgc gcagattgtc agaaaaaagt
     6721 tggatagctc cctcttcagc tttctcagtt aattctgtcc gaatacgacg ctcaatagca
     6781 ggcaagacct ttttcttaac ggattgctga acaacttcat caatataagc atttttcacc
     6841 ttgaaacgag tagcaaagaa ggcaagaata cggtccgtcg catgttcaaa accgatcttc
     6901 aagacaccaa gtttctcccc acgattgata gccaaggtac gatagccttg catagttcca
     6961 actgtctctg aaaaatcata ataaatctga aaaacctgct tttcatcaag actttcatcc
     7021 ttggcttgag aagtgagttt agagtgtctc agcacttcct gataagtcat agaacgcaag
     7081 gtcacatctt ccgataaggc ttcgaccaaa atatcaactg caccagtcaa ggcttccttg
     7141 ccagtcgcaa atccttcaca gacgaacttt tcagcttctt tctctaagtc aactatattc
     7201 tgcaaaatca aacgagcaag aggaaagagt ccagcttcac gggcaatggt tgccttggta
     7261 cgacgctttt ccttataagg aagatagagt tcttcaacgt ctgctaattt ttcggcaact
     7321 aagatagctt cttccaattc cttggtcaac ttaccttgtt cttgaatctt agctaagaca
     7381 gcttccttac ggtcattgag atttgtcaga cttttatcca aatcaataat agccttaatc
     7441 gccacctcat ccagactacc agtcatgtcc ttgcgataac gcgcgataaa gggaatagtc
     7501 gccccttcag ctgtcaaact tagaacggta tcaatttgct ttaacgtcac tcccaaatcc
     7561 tgagagattt tttcatattt tttatccata aatctattat accacaagct ggaaagcttt
     7621 ctccaatcct tttcatactc aataaaaatc aaaaagcaaa ctaggaagct agccgtaggc
     7681 tgctcaaaat actgttttga ggttgtggat agaactgacg aagtcagtaa ccgtactacg
     7741 gtaaggcgaa gctgacgtgg tttgaagaga ttttcgaaga gtatcaacta tcgaaaacaa
     7801 attaaaaaac tcccttttcc gcaaaataat agtataatag aggtagaatt tagaatcgag
     7861 gtacacctat ggctgtcaaa tttacaaaac gagacgactt ggacaagatg tttgaagagt
     7921 ttgctaaact ccctgatttg aaacaagtca ctttccctga tgacaaagag aaaaaagcca
     7981 aagcagaaaa gaaaaactag atgactgctt ttcaacaact cccatctagt gtacttcaaa
     8041 ctggagccat ttttctctcc attatcattg aagcccttcc cttcgttctg ataggaagca
     8101 ttgtctcagg gctgattgaa gtttatatca cacctgacaa ggtttatcat tttctccctc
     8161 gaaatcgttg ggggagaatc ttttttggga cctttgtcgg tatacttttc ccttcctgtg
     8221 aatgtggaat cgtccccatc atcaatcgtt ttctggaaaa aaaggttcca agttacacgg
     8281 ccgttccttt tcttgtgaca gcacctgtta tcaatcccat tgttcttttt gcgacctatt
     8341 ctgcctttgg caactccttc catgtcgccc tattacgagc tctgggttcc attcttgtgg
     8401 ctgtaatact aggaattttt ctaggatttt tctggcaaga accgattcag aaagaaaatc
     8461 gtctagcttg tcatgagcat gatttttctt acttgagttc tgcaaaaaaa gtttttcaag
     8521 tctttgtgca ggccattgat gaattttttg atacggggcg ttatttggta tttggctgcc
     8581 tctttgcttc tataatacag gtctacgttc cgactcggat tctgacctct atcagtgcga
     8641 ctcctctttt tgctatcctg ctcttgatgc ttttagcctt tcttctttcg ctctgtagtg
     8701 aggcggatgc ctttataggt gcttctcttc tctcgagttt cggtttggca ccagttctgg
     8761 cctttctcgt cattggtcca atgctggata tcaaaaatat tctcatgatg aaaaattact
     8821 tgaaagcacg atttatcagt cacttcataa cgattgtaac tcttgtcgtc ttagtctatt
     8881 ctctcttgat tggagtcatc ctatgattcg atttttagtt ttagctggct attttgaact
     8941 gactatttac ctccatctgt cgggcaaact aaaccagtac atcaacatgc actattccta
     9001 tttggcctat atctccatgg tgctttcctt tatcttggca attgttcaat tgtatatctg
     9061 gatgaagcaa gtcaaaaccc acagtcatct gaacagccga ttggccaaga tgacgagtat
     9121 ttctcttctg gctattccac ttgtcatcgg cttaactttc ccaactgtta gcttggattc
     9181 tcagaccgtt tctgctaaag gttatcattt ccccctatcg gaaggaacag atctagccat
     9241 tcagacaagc gaagggacga caagccaata tttgaaacca gataccagtt cttatttttc
     9301 aaaatcagcc tatgaaaagg aaatgcgaac ggcggcggat aaatacttat cccaagatag
     9361 tattcagatc actaatgaaa actatatgga agtcatggag gctatctacg actatccaga
     9421 tgaatttgag ggcaagacaa tccagtttac aggctttgtc tataacgacc ccagtcatgc
     9481 caatagtcaa tttctgttcc gcttcggcat tatccactgt atcgcagatt ctggtgtcta
     9541 tggattgctg accaagggca atacccggca gtatgaaaac aacacttgga taacagccaa
     9601 aggaaaactg gtcaatcact accataaaga actcaaacaa aaccttccaa ccttggaaat
     9661 cgacagcttt accaaagtcg ataaaccaga aaatccctat gtatatagag ctttttaaga
     9721 aaatcaagat aaaaacgaac aagttctctt ctgaataaca gaaaaagagc ctgttcgttt
     9781 ttttgttata tgaaaattag tgacttgtag attttcatct tataccattt ccagcaatac
     9841 aagtagctca tagaaaataa gcgagccact cattcattag actagcgatt tctttaggtg
     9901 cttgagtata aagctcatgg ccaaagtttt ctaaaaaaat agtatcaaaa tagtctggca
     9961 attcttttag ggcttcctct ctccatgtag ctttattagg atagcgagga ctaataaaca
    10021 aggtatctcc cacttctctc ttaaaagctt gtatttttct ccgtaggcgg agtagcgctt
    10081 ctatattttc ataatttata gccaactcat atctattata ctcaacattc cagtgataag
    10141 actgtcttac agctttctcc atattttctg accaatgctt tgcttcagat ttttctttag
    10201 aagtaagaac atctaagtcc aaaacaattt gagatttgat ataattttta gtttcctcta
    10261 actctgtatc caaaggtaaa atcttatcta aatctagata gccaccatcc aaaagaatca
    10321 gtttctttac ttcttcaaat tccgatgcga gataacgagc taaatctcct ccaagagaat
    10381 gacctatcag acaaatagat tcttcctcta caatctcatt tttaaaccat gatttcaatt
    10441 ctgtttcatc tcgaagatgc ttttcatatg gatttagaaa atagacctgc gaatctagtt
    10501 cttgaagaaa atccttgcta tgataggcat tgcttcccaa accgccaata aaatattttt
    10561 tcattctcta cttaatacta tgcttattca tcttttgttc aaagatagtt gtgataatct
    10621 gacgcaattc ttcgcgttct ttttctggaa tctcaccact tgtttgagct acagcgtaga
    10681 gttcagggtg ttcaattgaa atgcgtttaa tcgtacgtgt tgtagcatgt tttctgacaa
    10741 aaacgggatt cgcttaatca agtcttgtgg tactagcgcc agaatcttct cagcagtttc
    10801 tttgtcacta acattagaca ttgtaagcct tttcttaatc atttcctgtt ctttttctgt
    10861 aaaatctttt aattccattc gattagtcct cctattttct ctaggttaaa ttatgtacta
    10921 atacagatga aactacaaag aataaacttt aagaaatctt ctcactgata agattttagc
    10981 attagacttc ctgcgaaaca aaatatggta tagtagttct atgaattatg aagcaagtaa
    11041 acaactaact gatgcacgat ttaaatgtct tgttggtgtt cagcgtacca cttttgaaga
    11101 gatgttagct gtattaaaaa cagcttatca acttaaacac gcaaaaggtg gacgaaaacc
    11161 taaattaagc ctagaagacc ttcttatggc cactcttcaa tatgtgcgag aatatcgaac
    11221 ttatgaacaa attgcggctg attttggtat tcacgaaagc aacttactcc gtcggagcca
    11281 atgggttgaa gtaactcttg ttcaaagcgg ttttacggtt tcaagaactc ctctcagttc
    11341 tgaggacacg gtaatgattg atagccattc ccatcaatat cgtatctttg gatatagcca
    11401 ataaatgttt catttttgcg tggtttctgg ctattaacga ttgaaataac ccaccaactc
    11461 atcaaaaata gaaataaaaa tcctaagatt actgtcatat cataacacta ttaaagttta
    11521 acccacttat cattatccat gataaaaggc ttagccagtc cctcgcctgt ataatccgca
    11581 tacttggtgc ccaaatactt gtagcaatct tccttactag caaatttaat cgcttggtag
    11641 ggctcttcga aagtcaattt ctctacaaat aagaaaccgt catcagcagg tactaagacc
    11701 ccaacgtggc ctacaaacag atactcgcca tccaaattgt cgtgcaagac tacagacagc
    11761 attcgagctt tttcattgaa ttgaaattgt gagaagaatg tttccatctt ttcagcgtga
    11821 accttgacat ctgtagttgc ctcagttgga actctcgaaa atagaatatc aaactcttcc
    11881 ttatcttgtg aatcaaagac ctttccttta tcaatcgcat cattatctag gaaaagcaat
    11941 tggtcattct tttcaagctt tggaatggtg actgaatttt tcaaaagaca ataactattg
    12001 atacggcagt tggtcccaac gaaatcgccc ttcttttgat tccagagatg actgattttc
    12061 tcaacatcgt attcggtgtg agtaaaggaa gtgaaatctc ctgataagcc agttgagccg
    12121 acaatggtat tatagtcatt aacgagatta aaaaatgcat caacactatt tggatccaag
    12181 tgagctgata agagagattt gacctcttct gtacttacct ggttgtttag gttggtgtat
    12241 gaagctttcc atggaacttt cgctgaactg ctttgccttt gatttgtccc ctcagaagta
    12301 gcatgttgtt gttgacaagc agccaagcct aaaaacaaag ctgaacagat tcctaatgtg
    12361 gctaattttc ttgatttctt catttctttc tcctaaatgt cttggattaa agtttcttta
    12421 actactgctt tacagatatt gattactttc tcatttaatg tgttcatcgt ctttccctcc
    12481 gatttgtttt tttgttattt ccttaagctt gatttaatta tagtaggcgt ttcgtgctct
    12541 gtcaacaaat tttttacgaa aacacaacaa aggttttcat tttcgtggat ttcgtgttat
    12601 gctttactta caaaaataga aagcgatttt attcatagat aaagaagaga ttacgattgt
    12661 tagaggtgaa aaacatagta gattgaaata agatatgaac aactctatta ggaaagtcaa
    12721 attaattcct agaaatgttt tagcagctac agcgtactat tccaaactca atcaactata
    12781 aaacaatata gactagtaat ggttggactc aataagaatt gggtactaag ataggtataa
    12841 gtaaaaacac cattagaaat tatgaaaaaa gggttaggtc tactaaaaaa aatactatat
    12901 ttgacttagc taaagtattc agtagcttga tcgatgccct ctttcctcca gttcaaaagg
    12961 attctcctag cgatatccaa tctatctacg accaacgggc accacccaga caaggtaaag
    13021 tcctaaccta tgcctagagg caactgtatg agcagaaaaa cgaagtatcg taaaaatcat
    13081 cagactggac gactacagac agactactta ctctcgtgtt aggtagttta tctctgcagg
    13141 tagccgctcg atgcaggacg acgatttagt tatggagttt ccattatccc agacgactac
    13201 gacccaatcg cttatgtcgt cagcaagtcc atggaggcaa agataagaaa cagcgactac
    13261 ctatttatca agaatacccc acagattgac tataatacca tcggcatctt ccaagtagac
    13321 ggcgctaact atgtcaagaa actccgccaa ggctacctca aaaaaactca atcccgaata
    13381 ccccgacatc cacctagacg aaagcaacca tattcgtacc atcgggaaag ttgtcaggct
    13441 atatagggag aattaaaaaa ggggggagaa tggcgatata aaacaaacag attttaaaag
    13501 attcgaaaaa ctttgaaaaa gttcattcta catttcaaaa aaagaataag tgacctaaag
    13561 tagattagat tttgttaaac aatagtgata tgtaaattta gagaaaggca tttaagatca
    13621 ctttgcaaaa ggcaaatact aaactagaga aaccgataaa ccagcccctt agttcccata
    13681 ttttcaggca cacactcctt agtacactag ctgagaagaa tgctataatg gttagagtgg
    13741 aacacaaaaa cgctaaaaca gtaaataaca tctacactca cgtaagtaaa agaatggagc
    13801 aagctacttt ggaggtttta aataccatat cattaaatcg aaaatatatc agatcgaatc
    13861 tagacaagta cattacgatt gctaaaacat ttgtagaaat tcatttgact ttctaatcaa
    13921 tttgtgcata tcttatttca atcgattatg aaagttttgc ctctttgtta ccctctatac
    13981 aaaaaaccta tcacacaagc tctaaagctg gatatgatag gtttttatat ttttcttaac
    14041 gtactgtgcg gatacgcatt gtgtttgtgc gaacagcttc tcctactggc acaccagcaa
    14101 cgataacgat atcatcgcct gactcaacga gacctgcttc taccgcttta cgttcagcga
    14161 tttcgaacat atcgtcagtt gaagatggag catctgtcaa cattgggata acaccccagt
    14221 tcaacatcaa gccacgttct gtcaattcgt caaatgtcaa tgctaagatg tcagcatttg
    14281 gacggtattt agaaatcaaa cgtgcagtat gacctgtctt agtaagagtt acaaccaatt
    14341 tgatatccat tgagttagta gcatctttaa cagcagaagc cattacttct gtcttagagt
    14401 tacgctcaaa tgaatctgaa tcaagacgtc cgtattcatt aagaagagct tgagcgttct
    14461 tgtcgattgt agccattgta gttactgact cgagtgggta tttaccgttt gcagactcgc
    14521 ctgacagcat tgtagcgtca gttccgtcga taacagcgtt gaatacgtct gatacttctg
    14581 aacgagttgc acgtggtttt tcagtcattg tttcaagcat gtttgttgca gtgataacaa
    14641 ctttacctgc agcattgact ttcttgataa tcattttttg ataaactgga accatttcga
    14701 acggtacttc gatacccata tcaccacgag caatcataat accatcagct gcttcgatga
    14761 tttcgtctaa gttatcgata ccttgttggt tttcgatttt agcgaacaat tgaacatgtc
    14821 cgtttccagt ttcttcacag attgcacgaa cttcgttcac atcttttgca gtacgtacga
    14881 atgaaattgc gatgaagttg ataccttgtt caagaccgaa acggatatcg tcgttatcgc
    14941 gttcagcaag agctgggaaa ggaattttag tgttagggat gttcacacct ttttgtttag
    15001 cgatgatacc atcgttttca acttcaactt caaattcacg agttgcatca tctttagcaa
    15061 ccacacgaag accaagttta ccatcgtcaa ccaaaacttg acgaccaact tcaacatcat
    15121 catagatatc aagagcacca gcaacgttca acacaatcac ttcacgagtt gatttgattc
    15181 cttgtttagt tgcaacacga attttttcac cagttttgta tgaatattct ttagcttcac
    15241 cttcgaacaa ttctgtacgg atttcaggtc cttttgtatc aagaaggaaa ccaacttttt
    15301 tacctgcaat tttttccgca agtttaacag ttgccatacg ctcaccttgt tcttggtggt
    15361 caccgtgtga gaagttgaat cggaatgtgt tagcaccagc ttcaatcaat ttagcaatgt
    15421 ttttagctga agcttcaaca tcaagttttt caccccagta tccgtcctca ccgaattttt
    15481 taccaccacg gatttctacc gcaggaccca aagttgcaac gatttttaca cgtttgttca
    15541 tgatttttgt gactccttta tatatatgac ctttttggtc ttattaacta aattgtaaat
    15601 tatgacaagc tcttattcaa gctagatagc tcaatatcgg ctttgtgtgg gttgttaacc
    15661 acaatcttac cttctgcagt aaggctaaac aatgcccctt cttctgcagt accaagaatt
    15721 ggattttcaa ccattttttc gttacgaata ccaacagcaa caccaccgat accttcttta
    15781 agaagtttaa cagcatgtgc acccatacgt gacgccaaaa cacggtcacg cgcagttgga
    15841 gaaccaccac gttgaatatg tccaagttct gttacacgaa ggtcgcttgt atctccagct
    15901 tctttaagtt tttgaccaaa ttcaaccgct gacatcacac cttcagctaa gacgatgata
    15961 ttgtgttttt taccacattc ataaccagct ttgatgcttg ctacgatatc ttccatcttg
    16021 aagcctgctt cagggatgat gatttcatca gcaccagttg caataccagc ccaaagagcg
    16081 atatcaccag cgttacgtcc cataacttcg attacaaaag tacgacggtg acttgatgat
    16141 gtatcacgaa tcttatcgat agcgtccatg gcagtagtaa ccgctgtgtc aaaaccgatt
    16201 gtaaagtcag taccaacgat atcgttatcg attgtacctg gaagaccaat agctgggaag
    16261 ccatgttcag tcaaacgcat agcgccgtgg taagatccgt caccaccgat aacaactaca
    16321 ccttcaattc cgtgtttttt caattgctca atccctttaa gttgcccttc aagttgagcg
    16381 aactctgggt aacgagctga gtgaaggaaa gtaccaccac gagaaatgat gtcccctact
    16441 gaagctgcat ctaggggatg aatttcaccg gcaaccatac cagcatatcc gtcatagata
    16501 ccaaaaactt ccattccttc tgaaattgct tgacgaacaa ctgcacggat ggcagcgttc
    16561 ataccagggg cgtctccacc actagtcaaa acagcaatac gtttcatatt ggttatgctc
    16621 ctttttcttt taacattctt actgattata ccacatttac gttgaaaatt cttctatttt
    16681 ccgtaatttt agcgataaat cgttttcata actattccat tcaatttcgc ctctaattca
    16741 tcagatttag ctacaaaatg atggggagaa acgatggttt tctgttcctc ttcataccgg
    16801 atgatgactg ggattgggcc tttatactgg tctaaaatac gtgacatctc ttgatccgag
    16861 tcatgatttt taacctgaat ccaaaagcgc tcagccactg cttctcttat ttcttgtgca
    16921 atcatttgca gacgaccgtc acgtgactgg actttccctt tgatatagta gaatgctcct
    16981 tctcttactt cctgaccaac ctgtcgatat aaatctgaaa agagtgtaac atccaatttt
    17041 ttcttactgt catccacctg taagaaagcc atattttcac cctttttggt acgaattact
    17101 tttatcttct gaacttcaac caagataata gcatagctat tttctgacaa attactaata
    17161 ggagtaatcg gataaatagc cttatttgca atagcttgta gaggatgttt gctcactcct
    17221 actcctagga gctcttgttc catgtagaat ttttcttgct ccatccagtc ctccgaatct
    17281 tgccaactat aaatggtctc tccaaataag cttcctaaca ctttcacaaa ttcaaataga
    17341 ttagctaaat tattgaatac tttttgacga tttttttcaa atgaatcgaa aagaccaact
    17401 ttcaccaaag gttccagcaa gggaagtttc aaataattct caggtagttt agctaaaaaa
    17461 tcttcaatat tagaataagg tctatgttca ataatccaaa gcgccaagtc cttgctgagc
    17521 cccttaatcg atttcaaacc tatatagata gacttgttgg caattttatc gtgataggga
    17581 atagtattga tggatagaga ggctacttca aaacctgctt caagtgcatc tattaagtaa
    17641 tcactgttgg aagaatttaa catgacctga taaaaaatgg ctggataatg cgttttgaaa
    17701 taagccaact ggaaggccaa ggctgagtag gcgtaggcat gagatctatt aaatccataa
    17761 cctgcaaact tctccataac atcaaaaacc tgctctgctt tttccgcagt atggcctgct
    17821 tctatggagc cttgaataaa ggaagccctc atctcatgca tagcagaggc atccttttta
    17881 cccatagcac gacgcaaaat atcggccttc ccaagactaa atccagcaaa tcgctgagca
    17941 acctgcataa cctgctcctg atagagcata atgccataag ttggagccaa aatatcctcc
    18001 agagctgaat ctagaacagt cacttcttcc tgcccatgct tccttgccac aaaattattg
    18061 atgtagtcac ttgcacctgg tcgatttaga gaagtagtcg cgacgacatc ttcaaaacag
    18121 actggttgca cacgcttaag cagacgaatg gcacctggtt gctcaaattg aaagatacct
    18181 tttgtattac cagaggcaaa taaagctaac gtttctttgt cttctaaatc gatttcttca
    18241 attttcagat gaataccttc tgtttcagca agcaactctc gcatcttctg gacaaaggtc
    18301 aaatttcgta gtcccagaaa gtccatcttc aaaagtccgc tagcctcaac tccatgagca
    18361 tcatactgag tcagtggaat ttcatcacca tactttagag gaatgtagtt ggttaaatct
    18421 tggtcactaa ttacaacacc agccgcatgg acagaggttt gccttggata gccctctatc
    18481 ttgcaagcaa tctcaaaagc tttttggtat tctaacttac tattgatttg ctgacgaaac
    18541 tggagattgc cctcataggc caacttaaga ttgtcacgaa aactgatttt cttagtaatt
    18601 gcagataatt catactctgg cacaccaaag cgtttcaaga catctcgaag agcttgcttg
    18661 gctccaaagg ttgaaaaagt aacgatttgt gccgcatgtt tactaccata tttattacca
    18721 acatatctga taaaatctgg acgataaata tctgggatat caatatcaat atcaggcatg
    18781 gtatagcgtt cacgattaag aaagcgttca aaaatcagat ttttctctac tgggtcaatc
    18841 cccgtgatgt ctaaggcata agaaaccaaa ctgcctactg cagaacccct tcccattccc
    18901 atataatagc cattcgatcg tccaaaacgc aacaaatccc aaacaaccaa gaaataatca
    18961 tcaaagccca tatcatgaat aacagacaat tcttggtcta gtctatcttg atattcttta
    19021 ctagtcaacc ccttctgaac aagccccagt tcagcacgct ctctcaactc ctctactgct
    19081 ggtctagctg gattaaaacg aggcagtttc agactagtat ccaagtcgta agaaatgcct
    19141 gaaataagct tttctaaatt gtccaaagct tgcggaaaac gctcttggaa tagtttctct
    19201 aaagaacttg ctgatataaa gacatcttgt ctcgaacgca agggaacttc tctgagcggt
    19261 agattttctt taatcgctgt taaaacttga agaacttctc tatccctgct ttcaaaagcg
    19321 ttgacccgat aaagaggtaa gataggatga tgaaattcgc ttgctagtgt ttctggataa
    19381 acccctatat agtaatcaca gcctagttct aacgactcaa ctctatcaaa ataaggcaca
    19441 atgaccgcta tatcctccag gtactgggac aggactgacc aagttttctc cccctgcatc
    19501 ttggctgtcg aaagcttcat caactgctga tagcccacac tagatagagc taaaaagcgc
    19561 aaattcactc cctgatcatc tacaaacact gtcatttcaa gccctagcaa aggatgaatg
    19621 ccgtattttt ttgtaatctc tagaaagtcg aaagcgccat aaagattgtc aatatccatc
    19681 atagccaaat gagtgtagcc gtattcttta gctgctctca catacttttc gatcgaaatg
    19741 acgctttcca taaaactata gactgttttt gtatctagtt gtgcgatcaa tttacacttc
    19801 tcctctatcc ttctcactat attataccat tttcacctat aaatggcttc tcttgagaaa
    19861 aatttcatca gcttactaat ttattttcta ttcatttgta tttttgtcat catttttata
    19921 tttatactat attgtatata aaaatagaaa gcatataata taaatctcct agaactttta
    19981 taccctatct atttattctt attgttactc tgttctctat attgaattta gtactttatt
    20041 catttttatt ggattatttc cttttgaagt taacaattcc ctttctgctt tttttttgat
    20101 ataataacct taactgtcat tctatatgga ggttctatgc gttttaatca atatagttat
    20161 atcaattttc caaaagaaaa tgtcttatct gagctaaaaa aatgtggctt tgatttacaa
    20221 aatacagcca atcacaaaga ctcacttgaa acctttttac gtcgtttctt tttcacttat
    20281 caagacacca actacccact ttctatccta gcagctgata aaaaaacaga cctgctgaca
    20341 ttttttcaat cagaagatga actgacagca gatatttttt atactgttgc ttttcaactt
    20401 ttaggctttt cttatttggt tgacttcgaa gatagtgacg tttttcgtaa agaaactgga
    20461 tttcccatta tatatggtga cttgattgaa aatctctatc agttactcaa tactcgcacc
    20521 aaaaaaggaa atactcttat cgaccaactt gttagtgatg gtcttattcc agaggataat
    20581 gactaccact actttaacgg caagagtttg gctacttttt ctaaccagga tgtcattcgt
    20641 gaagtcgttt acgttgagtc tcgtgtcgat actgaccaaa aagggctatc agacctagta
    20701 aaggttagca ttattcgccc tcgttttgat ggaaaaatcc ctgccatcat gacagccagc
    20761 ccttatcatc agggaaccaa tgacaaggct agtgacaagg ctctctacaa gatggagggc
    20821 gagcttgagg ttaagcttcc tcacaagatt gagctagaga aacctcaact aaatctcgtc
    20881 caaccccaag gtaaagctga gcttatagca gaggctgagg aaaagctaac tcacatcaac
    20941 tctagctata cactaaacga ctacttcctt ccgagaggct ttgccaatct ctatgtctca
    21001 ggtgttggta ccaaagactc gacaggtttc atgactaatg gagactacca gcaaatcgag
    21061 gcttataaaa atgtcatcga ttggcttaac ggccgttgcc gtgcctttac tgatcacacg
    21121 cgccagcgtc aagtcaaggc tgattggtca aacggaaaag ttgctacaac aggactttcc
    21181 tatctaggta ccatgtccaa tggtcttgcg actacaggag tcgatggttt agaagttatc
    21241 attgccgagg caggaatttc atcatggtac aactactacc gtgaaaacgg tctggtgact
    21301 agcccaggtg gttatccagg tgaggacttt gactcccttg ctgagttaac ctattctcgt
    21361 aatctcttag ctggcgacta tatccgtggc aatgaagctc accaagctga cttagaaaaa
    21421 gtgaaagctc agctagaccg aaaaactggg gactacaatc agttttggca tgaccgcaat
    21481 tatctgctca atgcccataa agtaaaggca gaggttgtct ttactcatgg ttctcaggat
    21541 tggaatgtca aaccacttca tgtttaccag atgttccatg ctcttcctac ttatatacac
    21601 aagcatctct ttttccataa tggtgcccat gtttacatga acaattggca atcaattgac
    21661 ttccgtgagt ccataaatgc cttattgacc aagaaattac taggacagga aacagacttt
    21721 caacttccta ctgttatctg gcaggacaat acagctccac agacttggtt atcacttgat
    21781 aacttcggtg ggcaagaaaa ctgtgaaacc ttctcacttg gtcaagaaga gcaagctatt
    21841 caaaaccagt acccagataa ggattttgag cgctatggta agacatacca aaccttcaat
    21901 acagagctct atcaagggaa agccaatcag attactatta accttcctgt gactaaagat
    21961 ctccacctaa acggtcgcgc tcagctcaat cttcgtatca aatccagtac aaacaagggg
    22021 ctcttatctg cccaactgct agaatttggg caaaagaaat acctacaacc ttatccagct
    22081 attttaagtg ctagaaccat tgacaacggt cgctatcaca tgttggaaaa tctctgtgaa
    22141 ttgccattta gaccagaggc acaacgagtc gtgacaaaag gttaccttaa tttacaaaat
    22201 agaaatgatt tactgttagt agaggatatt actgcagatg aatggatgga cgttcaattt
    22261 gaactgcagc caactattta caagctaaaa gaaggagaca ctctccgttt agtcctctat
    22321 actactgact ttgaaatcac catccgtgac aatacagact accacttgac tgtcgacctc
    22381 gctcagtcca tgcttacctt accttgctaa aaggagttac attattatga ataaatcaga
    22441 acaccgccac caacttatac gcgctcttat cacaaaaaac aagattcata cacaggctga
    22501 gttgcaagcc cttcttgctg agaacgacat tcaagtaacc caggcaaccc tctcacgcga
    22561 catcaaaaat atgaacctat caaaagtccg cgaagaagat agcgcttatt atgttcttaa
    22621 caatggttcc atctcaaaat gggaaaaacg tctcgaactc tacatggaag acgcccttgt
    22681 ctggatgcgc ccagttcaac accaagtcct actaaaaacc cttcctggac tggctcaatc
    22741 ctttggttct atcattgata ctttgagctt ccctgacgct atcgctaccc tttgtggtaa
    22801 tgatgtctgt cttatcatct gtgaagatgc agatactgct caaaagtgct ttgaagaact
    22861 gaaaaaattc gccccaccat ttttctttga agaataataa atgactacaa ctaacaatta
    22921 tgcttttaaa aaacctggta gaaagtcttt aacatcagaa aacgcatagt atcaagtgtt
    22981 gaaaaccctt gatactatgc gttttgcttt atcctaggaa gatttatact cttcgaaaat
    23041 ctcttcaatc cgcgtcagct tccatctgca acctcaaaac agtgttttga gcagcctgca
    23101 gctagtttcc tagtttgctc tttgattttc attgagtatt atttcatttt ctcctgcaat
    23161 tgaattcttg ctcggctttt tgttttctat ttctttaaaa tcaaagtagc tcttttgtta
    23221 ataattcgat caacaaacat cgtggtacaa gtatctactt tgaaatttat caaccactta
    23281 acaactgata ctgtattcta ggaaaacgat gacattcttc ctaataaaac ttctcatata
    23341 tagcataaat ttctactctt tttaatttta aatgagtctc agcatggcaa tcactttaga
    23401 atttaagccg cttctccagc tcgattattg ataagttcaa tgatttgaac aatattacga
    23461 agtactggta gttggtgttg gaagagtagt tgaacagaac cataagattt aaacggctct
    23521 tgcgttaaca ctttcgtctc taaaaaacca ttttctacaa tgtagtctac aatcaatttt
    23581 acaaatgaaa tctgcctggc attaagattc tcatccgaca aaaatttaga aaaaatacga
    23641 ttggcagact ctctatctaa gccaataatc tcacgaacca atctcggaat tgccttattt
    23701 tcataatgac tttggtagtc tgctttacta cctaattttt cccaaagcaa tttttcaagt
    23761 gcaagcatat catcagatgt caacttttta ttatggtata gcttagaaat ggactcctca
    23821 tccagatgag ttttcaaata atgctcaact ttttcattgt aagaccgaag atcgttgacc
    23881 tgcaaaaatg ctgtggtctc gtgaacagtg gagagtatac gatcttcaaa gttaacatag
    23941 tagggtttac ggtctgtttt atccaaaaac tgtaataaat ctcgaatagc aagacgaatt
    24001 ttttccaaat cagacaagtt aacttctttc caaaattcag gctcctgtac tttcctgata
    24061 atttcagcct gctcaaaaac ctgcgggata ttgccaatag cagaaagagc tctagccgtc
    24121 ttcatcactt gggaaatatg aacagtggaa gatttagctg tcagttgccc caactgaata
    24181 tgaagcaacc acaaatcaaa tctcctggcc atctcatctt ctttatcttc atcaaataaa
    24241 agcggagaga gatttttttg aatggtttca cttgtaacag cagttagatt ctgccaactt
    24301 tccaatttcc tatagctata aactgtatct aaaaccatac gaaccctgaa gtccaactca
    24361 tttaagctct ctatacgacc ttgaagttcc gagacaagct gctgacggta tgctctcgca
    24421 aactgatctt cttggtattg gagtccctga agttctcgaa tcaagtccac tttgatatta
    24481 aataaacgct gagtcaacga aacaatgtga cgaccctctc catctcttgg atctgcacga
    24541 aaataatcaa aattgtcccc ataatcaaat accaagaagt tttccttatc ctgctcaggt
    24601 ccaaataaat ctttacatag acgggttcct cgaccaatca tctgccaaaa cttagtttta
    24661 gagcgtactt tcttgaagaa gactaaatta acaacctctg gtacatcaat acctgtatct
    24721 aacatatcga cagaaatcgc aatttgagga tacttctcct taattttaaa atcatcaatc
    24781 aaggtctgat aatgcttaat actataatca atcacctgag catagtcgct ccctttttca
    24841 ggatagcggt tgttaaaaat acctctgata tattccgcat ggtcatgatt tttagcaaaa
    24901 ataatagttt taccaatttc atcacccgag gctgtctgaa ttcctcttgt catgagttca
    24961 tttaaaacaa tttctactgt acttttattg aaaataaagg aattaaacac actcccatca
    25021 atatcttttt cacagctatc gtcttcaaat ttgctatcaa aatgttcctt ttcttcttcg
    25081 gacaaatcat cataatgtag accatccgta ggtagtttca gtttggtttc gatagaatga
    25141 taggctacta aatatctgtc tttaacagcc tcttccaaat catatgcata tgttggaacc
    25201 ccattctcca aattaaagaa tccataggtg tttttatcta aatcttgacg cggagtagct
    25261 gttaagccta caatccttgc atcaaaataa tcaaaaatgg acttgtattt ctgataaata
    25321 gaacggtgag attcgtcaat tatgataagg tcaaaatgcc caacagtaaa agggcgttga
    25381 tttacttctt cttgaccact aatcgctcca atcatggtcg gataagttga aaagaccata
    25441 cgacttgatt gagctccttc tttatcttct aagaagttac aaacggaaag atctgggagt
    25501 aattttctaa acgaatcata ggcttgctta accaaggaag ttctatcggc taagaagaga
    25561 acgtttttta cccagttatg acgtgataag atataaacta gagaaactgc tgtacgagtt
    25621 ttccccgccc cagttgccat aaccaaaagt gcctgtctac gatgattaga gaaagcttca
    25681 caaacgcttg caatggcatg tttttggtag tgacgcccgg aaatatcgtc cctaatttta
    25741 ctagaaatat cctcaagcgg tttttgaaga tgacgtctat ccatcactaa ttgcaattct
    25801 tcttgagagt aaaagcctgc aatctggcgg cggttcggac catcaagtat atagtgcttc
    25861 aacccatttg taataaagca aattggctga tagccgatat gtttctccaa agcttcagca
    25921 tattctttga cctgtacttc ccctacttct ggattgacag aggatttttt agcctccaca
    25981 atcgctaaaa ttttcccatt tttaccataa agtacatagt cacagtaacc aattcctgaa
    26041 ccgtgcttga gaccatcaac ggctatctca acacgacagt tttcttcaaa tatccatcct
    26101 gctaaacgga gatcgatatc aataaagagc tttcgtgtct ctgcctcaga taattgatca
    26161 atatggaaag gcacatcttg ccgttgcgct gcagtctcac gtttttcagt ataagtctct
    26221 tgaacttcta cggactgagc agccatctgt tcatgaaaat caggcagttc tggtaaactg
    26281 tcttgtaact ttatcataga ttgtggagtt tctcggtatt tgatgtttgc tgaaagtggt
    26341 aagcacttct catcaaaata acgctccaca aactcattgc tgtaacaata atcgataaaa
    26401 ttaacaaact gatacaaatg atgcaaagct aaaatcgctt ctcgttcctt aatttcacca
    26461 ccatgagcag catggtttcc ccaccgaatc aacagaacta tctgtttgtg gagttcagaa
    26521 tctacgatat ccctaaaatc atcatcccat actaaagaag atagagtagc acgataggga
    26581 gcttctaaat atgaatcgtg actatatatc caatggacag cctgctctaa agcacgacgc
    26641 gccataaagg cagtagccac agttgatgta gcaatcatat tctcagcttc aatgcaaggt
    26701 tttgaaaaag attcatattc gtcatttttt aaaagaaagc taaaatttcc catttttttc
    26761 tcactttaaa caaatagttt agctatatta tactaaattt caagctattt ctccacactt
    26821 ttatagctat ctcacaagca aattttgatt ccataatttc tcactttctt attcatcaat
    26881 aaaaagagac aatatcagtt tctgcattac agaattctaa tattgtctgt tcatttattt
    26941 tcttgtgctc attcaaatcc agcatactag gttacttttt gaccttttct ctaacagaat
    27001 gttcagaaac ccatttggag tagcttgtca ttttttcatc agttaaagct tctactgcga
    27061 tggttacaca catttttact gcttcttcta ccgttacaga aaaacgatag ccgtttaatt
    27121 gtaaaaattt gaccaaaacg aagaaagcag ttcttttatt agcattagca aaaacatgct
    27181 tctttatcaa ttggacaaat agtatcgttg ctttatcaaa aattgttgga taaagagatt
    27241 tcccaaagac aaattgttct ggtaagttca caatcatatt taaggcagaa gaactaactg
    27301 tttgaatttt ctcatttgga gaataccgtt gaattgctaa agcatttatt ttttcaattt
    27361 gcttttctgt cagatagatt gtcatttttc caccaaagct ttgaaaacat cgtcgtattc
    27421 gtcaaatatt ttatctaaat ttaagtcaaa ggcatcatca gatacataag aaacctgctg
    27481 ccccaattct tcaggagtaa agataatctc accacttggt aacaatttcg cttcgtattt
    27541 aacaccactt ggaatattaa attcacttgg aatcgtaatg gtgattgaat ttccttgttt
    27601 tcttgttttt actaccatct gatttcctcc tttgaagtat tataacaaat cattaccgta
    27661 attacaatgg cagaatatca gccaaaatac tcctgcatca gagatttctt caaagtttca
    27721 agttcttcca gagatttttg gattgccaat tgtgatttgt cgacctgggc tacaaagtct
    27781 gcgaactcat tttggagggc tagtgggggg agggggagaa gtattttttt taattttgta
    27841 attggtaact gaggctgagc acttcctgat atcactcgac tataattatt attccttaaa
    27901 acatggataa taaatttctg atttagattt ggtgtcttgg gacgtaatat taccatacct
    27961 gaatttatac gtaaatgttt atattttatt aattcatcgt agtacgctac atttccaaca
    28021 gtacctcttg ttgtcaagac tatatcataa cgctcaagtt tgccttttcg aagtaattta
    28081 tcctttgttt tagtgataaa ttgctttgta tcgaatgaaa atccgttttt agtaacattc
    28141 tttgtattta aaaataaaca gtactcctca ctaaacaact catctgattt aggataattt
    28201 ttacccctat caccatctat aatatcaaat aagttatcaa tgctttcaaa tattttattt
    28261 tccccaaaca tctcgttaaa tcgggatttg acgagcaagt ttagttcatc taactgaaat
    28321 tttcttttag taataagcct tttaatcgta ttaagaatac agataatgtt ctcttgttct
    28381 tcgataccta gcaattctaa ttgtaaatca agtaatatat tcttgtttaa atgaggaata
    28441 gttgcacctg ttgaatgatc tcgtaaatac tgcgatttac tttccaaaaa gactcccaag
    28501 taatctgata taattttttc tttgtatcgc tcattctttt ttaagaccgt aattgtacta
    28561 ccaacagctc ccgataatcc ataaccaact gttcctgcat tagctccatc ccatgctatc
    28621 agaatatcat ctgggagtgc ttcagtcata tttaaacttt cagtgaattt taaattatta
    28681 ttatttctta aatcatctat ttgaatataa cgttggctta gagttgtttg ttcagcaagt
    28741 acagtggctt tcttgccttt ttttagagat aagacttccc ccaacttcac ttttttcata
    28801 cagccacctc cctacttgag taatttttct aattcagcca agccagcttg aatttctttt
    28861 tctaaatcat tgattttctt taagatgacc tctgttggtt catactcaac tttttcatac
    28921 tcaatctctt tatatttatt gatagacaaa tcataatcat tttcctttat ctcagcaact
    28981 ggaacaaaga aagattgatc cgttctctga cgttctgctt ctttttcaag atgatgaaag
    29041 cgttcgataa tatctggaat atcattgtcg ctaatcggtt gtcgcttatc atccaaactt
    29101 aaaccatccg ctttcatatc gtaaaaccag actttgtcag tacctccatt accagttttt
    29161 gtaaagatga gaatggcagt tgaaactcca gcataaggct tgaaaacacc actaggcatt
    29221 gagattacag catcaagctt atgattctct acaatttcct gacgaattcc tttatgagct
    29281 ttagacgaac caaaaaggac accatcaggt acgataactg ctgctcgtcc acctggtttt
    29341 aaagttcgca agaaaagaga aagaaagagt aattctgttt ttttggtttt tacggttgca
    29401 agaaggtcat tagaggttga attgtagtca agtgagccct taaaaggagg atttgctaaa
    29461 accaaagtat atttatcggc ttcttcatta tcttgagaca gcgagtcaag gtaactgatt
    29521 tgtggatttt ctactccatg tagcatcatg ttcatcgccc caagtctcaa catagtcgta
    29581 tccgtatcat ttccatgaaa catctgatta tgaaaatgat tgatattatc tgtattggtt
    29641 tcccattcat ctttcttacg ctttaagtaa cggctagcag atactaagaa gccagcagaa
    29701 cccatagcgg gatctgagat gatatctttg atagtcggtt gcatcaactc aaccatcata
    29761 tcgatgatgt gacgaggtgt acggaactgt ccatttttac ctgcggtcga caattttgat
    29821 aacagatatt catagatatc tccgatatca gtaatacttt gtttgtcatt atcaaaatct
    29881 acatctaatc ccctagttgg aaaaacatct aagatagaaa ttgccttttg aagcgtagca
    29941 ggtttattta tttgaaaaat agcttctcgc atatatcgtg aaaaggctgt atcatctgta
    30001 tcccccttga gatttttaat aaacggaaaa atctcctgag tcattaaacg ataaacttcc
    30061 tgagcatctc ctatattttt aaaagttgac caacggtatt caggtttatc ttttggaaaa
    30121 actccctcat aaggaatccc tagaaattca gcatcacttt cacgtccaag ctcgacacta
    30181 tccaaatctt tcataaataa gagataagtc aactgttcaa tatttgttaa aggatttgcg
    30241 tttccttctg tccaaagaat ttcccacagc tgatcgattt tattttttaa ttcgcctgta
    30301 atcatatctt cccttttctt tagtttttaa aacttagtaa tatcattatt ttatcagatt
    30361 tcaaacaaag cttcaattaa ctatatctat gcgtcacctg aatattttat actcttcgaa
    30421 aatctcttca aaccacgtca gcttcacctt gccgtaggta tatgatactg actctgtcag
    30481 ttctatccac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgct
    30541 ctttgatttt cattgagtat taatagactt gtttggtatc ctgaaaacta tatcgtatag
    30601 gtgtcgtcat ggatcctttt agctgattta aggatacgaa aacacaatac tatgactcaa
    30661 ttgaaatgtt aaaattcaat ttctagccac ctaatcctgc ttcaaatagt tatcgaacaa
    30721 gttttatgat agctaccttg ttaggatgct cttatttttt accagacaaa acaaaaggat
    30781 taagggagtg aatttcctta atccgatagt tcttattctt gacgttgtcc gaaatcagca
    30841 atcatctgat ccatttcttg tcgactcgga gttgtcagca tataaaagta atctccttga
    30901 agttccgcaa aagcctctgg catgattttt ttaaccttga actgctggct atatttggca
    30961 agtaagttct cctcagaata gacatagtga gcatttgcac gacgtgatgt agccaaacaa
    31021 tactgaggtt caaactctga cgctgggaac tcttctcctg cgacaatggc tgcatatcca
    31081 cgatagaggt ccaaggaatg agcaaagtta taaacatcaa tggtgaaacc acctgcaggg
    31141 cggttattgt actcaatggt aatataatcg tccccctcac ggaagaactc aatatggaaa
    31201 aaccgttctt tcataccaaa ttccttaaca atcgcttccc catacttgcg tagtttggga
    31261 accatatcct tgagcacata gtaggaattg tccatcttat aaatcatgag atcaagcggt
    31321 gtataggcgt agtcaaaggt tgttgagaaa acaatctttc catccttgtt cacgagcccg
    31381 tcaaaggtac agatttcgct ggaagtgaca aatttttcaa agaaataaag ggttgaatgg
    31441 tcccattctt gcttgaagtg attgatatcg tcttctgtct caagtttaaa ggttgcggct
    31501 gctcccactc cattatcagg tttggcaatc attggaagac cgatttcttt cactgcttga
    31561 tcaacatctg cttccgtctt gataacagct ccaggtacca caggaacacc tgcttttttg
    31621 aaaagtttct tcatttcaga cttatatttc gtctttttga gatcctctgg tttggcacca
    31681 aaaacattga attgttctct gagtgttgcg tctagctcaa gccagtattc attgtgagac
    31741 tcgatgcggt taattggacc atgtttataa aagagaaaag ccactgcacg tttgacttca
    31801 tctatgttct caagattatc aacacgaaaa tactcggtca agctattgcg caagggctca
    31861 tccaattgct cgtaagactc ttgaccaatt cccaagactg tgatgccttt attagctagt
    31921 tcgatggtaa actgttgaaa gttttgtgga tagtagggag aaataacaag gtaattcata
    31981 ggtaactcct tttataaata gagattaccg aggaaataag gcatttgttt acgccatcat
    32041 tcccagtcgt gggcgacatc atgtccccat tcagcaaacc aggctggaat ttgtttctgg
    32101 tcaaaggctt ctttgagctt gtaaaaggat ggcaaaccat cttgttccca ggctccaagc
    32161 cccgtacaca gcacaatctc tgcctgacgg taacggtcaa taaaccagcc atcgttttgg
    32221 ttccaaatat aatctactgg cgagttttgg taaatagcat catcgttgta gtaatcaccg
    32281 acaaagaaac gtgcgtcgta aacaccactg agagcaatca ctttagtaaa gacatctgga
    32341 tgctggagga agaaattgag tgcatgatag gctcccatag agcaacctgt cgtcatcatg
    32401 ccatcaaacc aacctgtctt gtgcttgata aaaggaatgg cctcctcaat cacataacgt
    32461 tcgtaggcac ggtgcatttc cgcttggtca tgagcatttt tccaagtagc caaccaactc
    32521 tcactatcca aactagatag ggtaaagaac tggacaaggc cttcctcgat aaaggaagca
    32581 caggcatcaa tcatgccaaa atcatagtat tcgttgtgac taccacctga tgaagcaaag
    32641 accacaactg gaatcccacc atgtccataa cggttaaggt acatttcacg gttaagatga
    32701 ccactccagt ggctaagatg ttcaatatgc atttcgtttt ttcctttctt aacttaccat
    32761 ttttctgcaa aaaatctcag acaatctggt agattttctg accaagggat ttcactatgg
    32821 atggcaccag actgaacttt tagcacaaga ttatccagat gtactccccc tgctatcaaa
    32881 tcatggtaat agcaaagcga cgagtcgata taggcttgtt tgatattgcc atccatcaag
    32941 gtcttgtctg tatcatctgc ttcttctgtt cctacataga tgaagatgcg ctggtcaggc
    33001 gatagtttct ggcactcgat atagcggtta aaggcttctt ggtggagcca gtttgcagat
    33061 gaaaaaacgc ccaagcaacc aatttggtct tggtattcca aaccgataaa ctgggtaata
    33121 ttgcctccta gtgaggaacc aatcatagcc gtatgctggc agtctgcttt tgtacgatag
    33181 gtctcatcga taaaaggctt gaccacctcc atgacaaact cagcatactc cacaccctta
    33241 ccaccaaact gctgctctgg gataggagat tcttggaact tccaagccgc atactcattc
    33301 attcgcccca taccatcatt gtcaatagca acgacaatca tgcgactgat atccggattt
    33361 cgtttgatag ctgggataat cttccatgaa tatccaatga aagactcttt gctataaaaa
    33421 acattttgcc cgtcatgaaa gtatacaaca ggataggaac ggtctgtatc tttctcataa
    33481 tctttaggaa gaagaatacg tacacggcgc tccttacctg tataaggaac cttgagtttg
    33541 tgttctttca tttttagata aaagtaggat tgattcattg tcagaaaact ctctatattc
    33601 aaaattttat atcattatat catgaaaata gaaaaaagtt agttttttac ctgtttttag
    33661 aaaaaaaaac taactttttt tactgatttt cgctattctt ttggattttc tgaattagag
    33721 tagattatca atcaagtcat caacttcatc tttttcggct tgaggtgtga tttcagtaat
    33781 catgattcca gccactgctc gctcaaccaa gccttcaaca tccatacgcg cttcgtactg
    33841 ctccgcattc ttaattttag gatttgtttt tggacgatct ggtgcaaaaa tggtacaaca
    33901 gtcttcaaac ggttggattg aaatgtcaaa ggtatcgatt tcctgggcga tgtcaatgat
    33961 ttccaacttg tccatggtaa ccacaggacg aatgatggga gtgttggtaa cagcattgat
    34021 agccttcata ctttcaaggg tttggctggc tacttgacct agactttccc cattgatgat
    34081 aaccaaacca tttcgtacct cacgaatacg gtcagtaatc cgcatcataa agcgacgagt
    34141 tagagtcatc aaataagctt ctggcgcttt ggctttgatt tcctcttgaa tctctgtgaa
    34201 aggcacctcg ataaactgga tatttccgcc aaacttggtc aatttacggg tcaagtcctg
    34261 cgctttcttg agggcaccag gactagtata tggtggacta gcaaagtgaa ctgcctcgat
    34321 atccacccca cgcttaagag caagataacc tgctacaggt gagtcaatcc ctcctgacaa
    34381 catgagcatc cctttacctg aagttccaac tggcaaacca ccagccccac gaatggtttc
    34441 ataagaaaga taggctgctt cttcacgaat ctccacctga agattgatgt caggactttt
    34501 catttgaact tgcacatttg gaatggcttc gaatacagcc cctccaagtg tttggttgag
    34561 ttcacgacta tcaagttcaa agttgtggtc gctacgcttg ctagaaatct taaaggtcat
    34621 accttccttg tagatgtccc gcataatctc ttggacagaa gacttcaaaa cttctacaga
    34681 tttttcaacc ttataaacag gagaaaagtt ttgaattcca aaaacttgtt tgagagattc
    34741 tgcaactgct gtgtaatcag ctccattgag gtaagcgtgg gcacggtcgc gatctgctgt
    34801 taccttaact tgggtataga tagacaaaac gtccgaaata ttattacgaa gtttattgat
    34861 gaaacgcata cggtttttac ccttggttga caactctccg tagcgaatca taatttctga
    34921 atactgcatg aatgctccta tcttactttt ctagtttgat tgtaaatcaa ttttaacttg
    34981 gtcaaaaact gctcgacctg actcatatca ttttccaagt ctaggctaag acgcacagct
    35041 gacttggcct tatctttgtc cactcccatg gcaatcaagg taccggctgg ttttcctgcc
    35101 ttagatgaac aagctgaggt tgttgagatg aaaatatcat agtcttcaaa ggcgtgaacg
    35161 atgacttcac ctcgaacacc tttgattcca aaagtcagaa tatgaggtgc aaagtcttcc
    35221 tcatctgaaa agacaaaaat atccggatag ttcagaagag cttggtgaat cactgccttc
    35281 atctgcccag tcttgctcct aaagatatct agcttttcca tagataaacg gagagccttg
    35341 gctgtcgctg caatccctgc cacattttca gttgtcgaac gataatctcg ctcctggcca
    35401 ccacctgtaa gaagaggtgt aatcttcttg ccagatttga tatagacaaa gccaacacca
    35461 cggacaccat gaaatttatg actcgagaag gtcgcgcaat ccacccgttc tgtcagatac
    35521 ttttcagtcg gaattttggc aagcgcctga accgcatcaa cgtggaagga aatagtcggc
    35581 ttgtctgcca agaattctga aatagcctca ataggttgga tagagccgat ttcattgttc
    35641 acagccatga tggaaacgag gattgtatca ggccgtatca aacctgctaa cgcctcaaca
    35701 tcgaccaagc ctttcttatc aactggagca aaatccactt caaatccttg acttttcaac
    35761 cagagggctg actctttgac tgctggatgt tcaatggctg aaacaatgat gtgcttgcca
    35821 aactgagctt tttcaaaggc cacacccttg ataacccagt tatccccttc tgtcccacca
    35881 gatgtaaaga agatttcatc acttttctta ccgattaaat ctgcaatctg ttgacgggaa
    35941 gcatctaaaa ttcgtgttgc ctggtctccc aaacgatgga gactagatgg atttcctaaa
    36001 atttttgaag ccacctgcat ataggtttca agggcttctg gatagggcct ggtcgtcgcc
    36061 gaattatcaa agtaaatcat gtttctcacg ctttctaaaa tcactccttc tattgtatca
    36121 tgaaacggag cctgcgacaa gaaagggcaa tgtttgcatt aatctgaata acataaaata
    36181 ctcttgatac catcatcaag agcattctta ttcattctat ctaactttga ttatttctgt
    36241 taaaaatcta aagaaaagta attttgtccg ccccagagat taaccgctcc ccaaggcgaa
    36301 tttactccta cacctatatg gactgtacca tttgcgcgtt ggccatatgg aatcgaactt
    36361 ttccaagtgg aacgattact tatcgtatta ggaaaccaag cccagtcagt gaaatacata
    36421 tttgacacac tgccactata agtatcagaa tagccagaag cattaaaagt cacattaaga
    36481 acattcaagc ctaccaagct ataaccgtct aaagaactag acttacttac ataatctgca
    36541 tgtacttgac ttaaaaatgt taaccatggg atagcaaaca ctaccactat tatttttttc
    36601 attatcttat gtttcatgat atcacctcat ccattctttc ggatagtatc gacaactgtt
    36661 tgcctacaag ttgtgtatat aggtagtaag ccacttatta tcagtactga gactgataat
    36721 ccaattaagg tgaaaacgga agttagatag aatttaaaaa catctgaaat ttccaattta
    36781 agcacttgca ttgctaaaat ggaaagaatg acgagtaaac aacttgctaa tatcgaaatt
    36841 gttttaccat aaccaattaa ttcttttaag aaaagccaaa caatattttg agtactgtat
    36901 cccaaagatt ttaaaatccc tacttcaaag cgtcgaggac gattgagcaa aaagaaaaca
    36961 aaggacaata ctgcgatgac aaggatgagt aagactaggg atagcaacat taaaaattgc
    37021 ctgatatagg tgagtccttt attaaattct tcgtagtttt catatgatga taaaatagta
    37081 atttgtgaag agattgctct tattctactc aattcttcag gaatagcacc gctatccttt
    37141 agtaacacat gaatcgcact cggcatccat gatttcaaag gaaaaccatc taaagccatc
    37201 ttcgtcatgg gatgctgttg aattgcttca ttttgcaatt cttccatttc agcaatattc
    37261 ataaataggg tgttcccata aggggaatat tcaaacggat aacttttttt aacaatccct
    37321 aaaacaggat atgttttatc cactttgaca aataaatcgc catctccttt caatatattc
    37381 ccctctttct ctatacttga ttcatataaa gaaattggaa tataaaaagt cagtgtcacg
    37441 gtagttcccg aaactatatt tggtaatttt tcatctgaaa tgaattgctc agatagataa
    37501 atcccttttt cattgctcct atcaaaatac tctatctgcc tctgtgttgt atttgtctga
    37561 tacaagggtt gaattgaaaa atttcttgtc aagcttctgg tctgaccatc aatagtcaaa
    37621 gttggctgaa agttcttttg aagttgtgaa tagtcttttg aattatcaaa cgtcataccc
    37681 aaagagagaa actctatata aggattgacg gtttgaatat tctgacttgt gctaattgag
    37741 gtgatttcct ccttatcaaa actgagaaaa tcatccaaca cttttgtagt ttgtaaatga
    37801 agcgaatcat taatcaccaa gaagccattt tcgagtgagt tgttcaccag ttggtgatac
    37861 ttatctgcaa ataaggactg aaagttaata gaggttactg ctatagcaac tacaagagag
    37921 ataaaaaacg ctaataatct aggtaaaaaa ggccttctat gtttcaaaac ggatagcttc
    37981 gtatgagaag acgacaaaca ggaggaccac ttcttagaat cctttatccc ttcatcagaa
    38041 ttcaaaataa gacaattccc aactaattta tggtctttaa aatgaagctg aacatctcct
    38101 attgcaatca tcgcctcatc atgcgaaaca atcaatacaa ttttatgata tttgtgagct
    38161 aaatcaatta acaaggcgga gactttttct ctattttctt tatccaaaga acttgttggt
    38221 tcatcagcta agatgagagt ctttcctgta actaaggctc ttgcgattgc cactcgttgt
    38281 tcttcaccac cggataaatc ttctggataa gcatgcttta aagaagaaat ctgtaaatcc
    38341 gccaatactg tatcaatttt gctttctatt tcatctggac tcaagtcata aaagtttaaa
    38401 gctagtctta aattttcaaa tacggtcaaa tcatttatta gatttcgccc ctgaaataca
    38461 aaggcaactt cttcagctat aaagacagag actgatttct tattttcgat atcaatctct
    38521 tttccatcga agaaataaga aacactagga tccgtagcag agagcaaacc aattttattc
    38581 agtaaagaag actttcctac gcctgacttc ccatatattg tatatacttt tcccctttca
    38641 aatatcaaat ctgttggctc tagcaaccgc ctgcctgcaa aagagagact caaatttcta
    38701 atttcgaaca tataacgccc tccttttttg aaatcgcttt ctttatttta ttatatcata
    38761 agtcatattt tatttcaact aattactgaa gttcgtgtag aaaaatctcc tcttttttta
    38821 agattttttt aaagaaacag agtataataa atcataatca aaggagagaa tgtatgtcta
    38881 actatcgtag aacttcaaaa ccgaaaacag aacatatcaa aaaaggcttt actgtttttc
    38941 aaaaaaccat tactactatc ggtagtatcc ttggtttgat tacagcgggt atcacgatca
    39001 tgaacgcctt ggataataat aaaaatacta aaaaagaacc tacgacaagc cagacgacaa
    39061 cctttgtcaa agaaattcaa aaagaacccc ctcaggaaaa tactactcca aataaggaaa
    39121 ataacacttc tcaagaaaaa acacaacaag aagaaacgcc aaaatctagc gtcaaggaag
    39181 agaaaaaaga agatcagaaa acagcaactc aggactctac tacacctgcc acaagtaaac
    39241 ctgccactga aaatgaaaaa cagcccaata ctccaacttc agaaaataaa agtaatcaat
    39301 aaccagaaaa atagcttcct tccaaccttg gaaagaagct attttttatt gctgcaatac
    39361 ttttcttggc ttggtacctt cagctggacc aatgacacct gccatctcaa gctcttccat
    39421 gagacgggtc gcacggttaa atccaactga caaacgacgc tgaatcatgg atgcactggc
    39481 tttctgtgtt tcgataacca aagacttagc ttcttcaaaa agcggatcac caccagcatc
    39541 tccatccgaa aattctcctt cattttcaga aacctcacct ggatcaaaac tctcatcgta
    39601 gtctgcatct gcctgagtct tgatgaagtt cacaatgcgc tcaacatcgt catccgagat
    39661 aaaggagcct tggagacgaa ctggatgatt ttcatcaatc ggtttaaaga gcatgtctcc
    39721 tcgaccaaga agtttttctg ctccattttc atccaaaatc gtacgggagt ctgttcctga
    39781 tgaaaccgca aatgctacac gagatggaac attggcctta atcaaaccag agatgacatc
    39841 aacagatgga cgctgagttg caagaatcat gtggatacct gcagcacgcg ccttctgccc
    39901 aagacggatg atagcatctt ccacttcctt gctggccacc atcatgaggt cagccaactc
    39961 atccacaatc acgacaatga atggtagcgg aatttgcttg tactcagact gggaattgaa
    40021 ctcttctacc ttggcattaa aacctgcaat attccgaact cccaccttgg caaagagttc
    40081 ataacggttt tccatttcat ccacaacctt ttgcagagcc ttgctggctt tgcgtggatt
    40141 ggtcacgact ggaatcaaga ggtggggaat atcattgtaa acagataact caaccatctt
    40201 gggatcgacc atcataaatt taacttgatc tggtctcgcc ttcatgagaa tgctagcaat
    40261 aatgccatta actgctactg acttccctga acccgttgaa cctgcaacta gcaagtgggg
    40321 cattttagaa aggtcaaaag ctcttgcggt tccattaaca gccttcccta aaggaatttc
    40381 caagaaattt tctgctttcg tttgcgattg ttcccatagt tctcggaaag atacagtggc
    40441 aatatcggag ttgggcactt caattccgat tagggatttc ccagggattg gtgcttcaat
    40501 ccggacatct ttggcagcca aggctagagc gaggtcatct gatagattgg aaatgcggtt
    40561 gacccttaca ccaacagccg gcttgacttc atacttggtc actgatggcc caatttcggc
    40621 ccgttcaact gttaccttaa taccaaagct agcaaaggtt gcttctaaga ttttgatatt
    40681 ttctctgaca attttcttct ctttagactg atcttttggt ttatctggtg caaagagttg
    40741 taagcttgga agtttgtatt caagggcttc tttggctgaa aaatcgacct gaacatcttc
    40801 gtcatctgag tcatcttcct gttcagggaa tttaagttca gcttgaggca ggatgatttc
    40861 tggttccacc cacttttctt ctggaatagg tggaagattt tgaacagctt cctctgtcag
    40921 aatttcaccc gtttccatat caacaggagg caaatcgagt aaggcttttt cagtctcttc
    40981 ttgttctaat ctagcctctt tctcagcctt ttggcgagct ttttcttctt gtttgacaaa
    41041 gcgttcctct tttcgacgct cgtgcccttc ccaccatttg gcaaagcctc tactgaaaaa
    41101 ttcagcaata tcgtaaacag accaagggct gactaggaga gaacccacta aaatcaagat
    41161 agaaccaata aagtaagttc cgatatttga aaagagaaag gctgttggaa tataaagagc
    41221 gaccccgatc aaaccccctc cagcaaagct agtcgttcga aaaccagtca gatctgtcac
    41281 aacctgagcc atggtccctt ttagaacgga cttgtccaaa ccatatttcc aaaccaagta
    41341 ggcctcaaaa atcaagagta agccagcaaa tatggtgaaa aagccagata agagtccttc
    41401 ctgttttcgt atccacttga aaaagaagag atagattaat aggccgaata tcgccagata
    41461 agctaggcta cccattagca agcgaattaa attataaagg gttatacctg cagcccctaa
    41521 tttgaaggct gcgaaaatca ataaaatcgc aattcctaac gaaatcaaca ttcgttgaat
    41581 cgcttctttt ctttccagtt ctgctttaga cggtctccgt cttgttgtac ttgtattctt
    41641 gtttgccatt cttctattat accatatttc acaggcattt cggaaagaga aaaagactgt
    41701 accaaacggt ccaatctttt catttttcta ttttttatgc ttgtggtttg cgtaggtaac
    41761 cataaaccac accacttacg attgctccta ccaagacaga aacgaggtaa aggagagcat
    41821 ttgaagtaag ggcgataacg aagattcctc cgtgtggcgc catgagtttg ataccagtaa
    41881 gaccaacgag tccacctgct actgctgaac caaggatgaa gcttggaatc gcacgagctg
    41941 ggtcagcggc accaaatgga atcgctccct cagtgataaa tgacaagccc atgatgatgt
    42001 ttgtcaaacc agagttacgt tcttccttag taaatttatc tttgaaaaga agagttgcga
    42061 caaagattgc aagtggtggc accattcctc cagccataac tgctgccatg gctacagaac
    42121 cacctgaaga aacagttgct gcaagcgtac ctgtaccaaa gacataagct gctttattaa
    42181 ctggtccacc catgtcaaca gccatcattc caccaaggac gataccaaga aggacagctg
    42241 aacctcctcc aagaccgcct aggaagtcat tcatagcagt gttgattgct gccattggga
    42301 tattcacagc tagcataaca aatcctgtca agattgttcc aagaagtggc aatagaagga
    42361 ttgatttagc accttcgagt gaacgaggaa ctttaacgta tttcttgatg gcaagaacca
    42421 aggcacctgc gataaatcca ccaacaaggg cacctaggaa accagatgag acacctgcaa
    42481 gagttgaagt tgcttcacca cctgcggcat aaggaatttt accaaaggca aaaccttctt
    42541 tggcaatagc accagccacg aaacctgcta ccaaacctgg tttttcagca atagagtagg
    42601 caacataacc cgcaaagact ggaagcatca aaccaaaggc agctccacca attttcatga
    42661 acatagaagc taactcatgg taagaaccaa gattgccaag gttttcattt ggaacactca
    42721 aagcaccgtc aatcaagaag gcaagggcaa tcatgatacc accaccgata acgaatggta
    42781 acatttgaga tacaccactc atcaagtgtt tgtagaaggc accaccaagg ctttgttttt
    42841 cgttagaggc tgttgcgact ttggcaccat tagcggcacg gtagacttca gtatctcctg
    42901 aaagagccaa gttgatcaat tcttctgtct tacggatacc gtcagcaact ggacgattga
    42961 tcaaaggttt gccatcgaaa cgatccattt caactgcctt gtctgctgca atgataatag
    43021 ctttagcctt acggatatct tctgcagtta gttgatttcc aacaccgcta gcaccgttgg
    43081 tttcgacctt gataccaacc cccatttcag cagctacttt ttgaagggct tcttgggcca
    43141 tgtaagtgtg ggcaatacct gttgtacaag ctgtaacagc tacgataaag tcaccagagt
    43201 cattagcagg tgcttgaaca agttcctcag ttttttctga agcttggtca aaaagttcga
    43261 taacttggtc tgcagatgtt gcttgacgaa gtttgtctgc aaaaccgtct ttcatcaagt
    43321 attgagacaa ttctgccaag gctgccaagt gagtatcatt ggcaccttct ggagctgcaa
    43381 tcatgaagaa gaggtcagtt gcttgtccat ccaagctctc gtagtcaaca cccttatttg
    43441 acttagcaaa tagaactgtc gcttctttga cagcagcgtt tttgctgtga ggcattgcga
    43501 ttccatcacc caaaccagta gaagttaaag cttcacgcgc caaaatgcct tctttaaagg
    43561 tttcaaaatc tgtcacataa ccgtggcctg ttaggctttt aatcatctct tcaatgacag
    43621 cagtcttttc agttgcctgc aaatccagca acatgacatc ttttctcaat aaatcttgaa
    43681 ttttcatcgt ttttctacct caacttttcc atatgtttct ttaataaatt ccgccgttgc
    43741 caagtcatct gagaaggtag ttgccgttcc gcaagccact ccccatttga aggcttctac
    43801 tgcgtctttt gatttgacaa attcacctgt gaatccagca accatagaat caccagctcc
    43861 aactgaattt ttgactgttc ctttgattgg tttagcgaag taagctccct cagatgtgac
    43921 aagaagggca ccatcaccag ccatagagat aataacattt tgagcaccct tagccagtaa
    43981 ctcacgagcg tatttctcaa tttcatctaa actttcgagt ttaaccccaa aaatcgctcc
    44041 aagttcatga ttgtttggtt ttacaagaag aggctggtag tccaaactat caattaaggt
    44101 ctgtccttca aagtcacaga ccacttgcgc accagtctgg cgcgtcaagg aaatcaaatc
    44161 cttatagata acattgccta gatttttagc acttgaacct gcaaagacaa ctgtatcttc
    44221 tgctgtcaga ctagataaaa tagctttcaa ttcttctagc ttaaccggtt caacagttgg
    44281 acccgttccg ttgatttctg tttcttggtc tgctttgatt ttaacattga tacgagtatc
    44341 ttctgccacc tggacaaaac gtgtctcgat ttcttcctct gctaaagtat ctgtgataaa
    44401 tttaccagta aagccaccga taaatcccgt cgctgtattt ggtatattca aacgtttcaa
    44461 gacacggctg acattgattc ctttcccacc agcaaactta tcatcactgt ccatacgatt
    44521 gacactacca actttgactt ggtccaaacg aacgatatag tcaatggatg gattgagtgt
    44581 gactgtataa atcatacttc tattacctcc gttttctcct taataacctg caagagctca
    44641 tgcccttgac tagtgataac gatagcgcgt ttgagtgggg ctaccttggc aaagcaagtt
    44701 tgtccaattt ttgacgaatc caccaagacg taggtctgct tggcattctc caaaatagct
    44761 cttttcacag ctccctcctc catatcagga gtcgtataat agccatcgtc aacaccattt
    44821 attccgataa aggcacggtc aaagtgcaat tggttaatct ggttaagagc aacgcccccg
    44881 atactagcat ctgtcgccgt cttgacgttt cctccaacca tgacagttgg aatctgcttt
    44941 tcaaccaact gagcggcatg gtgaatggag ttggtcacaa ctgtaacatt cttattgacc
    45001 aattcatgaa tcaaaaaagc agttgttgtt ccagcatcga taaagatgac atctttttct
    45061 ttaatgagag aggctgcttt ctgagccagc aacttctttt cttgaaggtt tttgacagat
    45121 ttttcttgaa tggtttcttc ttcctgtaag gagtggggga gttctgctcc accatgcaca
    45181 cgacgaagct tgttttccgc ttccaactca tccaagtctc ttcgaaccgt tgattctgac
    45241 gtttctagca aactaactaa tttttctaga gaaactacat gatgttgatt taactcctct
    45301 aaaatcagtt gtttacgttc tgtttttaac actgaatcac ctcctgttat cgtttacact
    45361 attcattcta ccatacttta tttcgaagtc aagcattttt tgtcgttttc tttcaaaatc
    45421 tatcattttt cttatttcta gaatttttat tgcaagataa gagcctttat ggtagactat
    45481 ttgagtaagt attggaagat tactcaagag gcttaagagg ccgtgttgga aacgcggtag
    45541 gcgtgtaata gcgtgcgtgg gttcgaatcc catgtcttcc gtcgaaaaaa gattattttt
    45601 aggatgcgac aaatgttgta tcctttttta aaatagggtc tgtttgtgac tcccttttta
    45661 gcaaaagaat gcaaaggaat accaaatata aaaataaaaa acgttgattt aacaacgttt
    45721 taccaaggaa tgcaaaagaa tgcaaaagaa tgcaaaggaa taatggagcc ggtgggagtc
    45781 gaacccacgt ccaaacacct gccaacatat ttgtctacaa ccataggtta tgtattattt
    45841 taacagcccc tcgacacata actcaagtct agaaactgcg agtctatcaa tctcttatca
    45901 agccgctaga caaggcttaa tcgtatctcg ctaataataa gacctgtcat tgaacacgag
    45961 caatccaaat cgggtcacgc ctgctggttt ttaggcagct agagcgtaag aagtgttatt
    46021 ttttgcagtt atatttaact gagcgtttac gtcgccacac gagtcgcaaa atatgcctca
    46081 taatgcctgt cgaatccgta acgaccccaa aagacaataa aactattata ccttatctaa
    46141 ctcaaaaatg caaaaagaaa tcacatacct aaaaaagata ctattcgaga aatttagcaa
    46201 actggaagac taactacaac tttctcagtg cataacttta cgattgtaaa tagagcttac
    46261 gaaatccaat taacacatac ctaagatgaa gctatctgtt ttgaagaaat tcacgaagag
    46321 aattattcta aaatactttc agatgagaat tttcgtactc tctttatttt aattcatttg
    46381 agtttaaaaa ctataaaatc aatccttata ttattcggac tacttttcac ttattgcacc
    46441 aaaatatagt aaaatgaaat aagaatagga cgaatagatt aggacagtca aatcgatttc
    46501 taacaatgtt ttagaattag aggtgtacta ttctagtttc aatatactat aaataggttt
    46561 cattcgaact ttaatagact atgaaaacca gtggaactta ccctgacaca gaattccact
    46621 ggtttttcga tttttatcag attaacttct actattctta gctgtgaaaa ttagtttaag
    46681 actttaactt attttcagtc ttctaatcta aaggccactt ccagtaaaga aaaatcaggg
    46741 ttctcctgac ttttacttag ctaattctct ttctcgttct ttcattattt tatgattttc
    46801 atacaaacgg gataagaact tagaaatttc tttcaagata gaataggttg gcactgcgac
    46861 aatcattcca actacaccat agatattgct tgacaacaaa agtaaaacta aaatcgtgat
    46921 tggatgaacc ttcataacac ttcctacgat tcgaggatat aagatattgc catctacctg
    46981 ctgaacaaca agcatataaa tcactgcaat cagcagtcta tggggatcag tgaatatatt
    47041 tgcgatgatc ataggaatca aaccaatact tggccccaca taaggaatta aattggctac
    47101 accagaaaaa atggcaaaaa ctaaagcata ttttaaacca ataatactat agccaatata
    47161 agccaaacaa cctataatga ttgcgtcaat cgaaactcca ctaatatagc gagcaatcgt
    47221 cgcatttaaa ttctttaata agcctgcaat atgcaagcga tccctcttta gaatcgttct
    47281 ttcaagcatg ggcaagaatt tatgtccatc taataagaaa taaaccaaaa aaactggagt
    47341 cataatcaaa atcaaaacag tactgataag agctgacaag acgctcccca cactatttga
    47401 tacgctattt aggatatttt gaagaatatc aacataggat aagtttaact gctgaattgt
    47461 agcttctaca tccaaattct ggagcgcagg ataattagat aagtctatga ttaagtcttg
    47521 tactcgacta taaatagttt gactagatat aatcaaacta gataactgat taatcaaaat
    47581 aggtaagaga tagacaacac ctatgaccat tccccagacc aaagtacaca aggtaattaa
    47641 aataccaagc aaacgattga gtttacagac tttatttaag aaagtaacaa tagggtttgt
    47701 caaataataa agaaagcccc ctaataaaaa tggaatcata attgtattaa gcacgctaac
    47761 aaaagggtta atcaaagacc ccatctgtct ccataggtaa aagatgatgg ttaagagtaa
    47821 aatttctgtg gtccaaaaaa ataatttatt tctacgaaac atgagttacc tccctcactt
    47881 tattttacca tattttcaaa aagcttaaca gatgaattat taaagcaaga atattttttt
    47941 tctttatgat agaataagac tactatgaaa aaaatatttt taactttgtt aactgtctct
    48001 cttttagggg gtgcttctac tgctgttgct caagatttta ccattgccgc taaacatgcg
    48061 attgctgttg aggcaaatac tggtaaaatt ctctatgaga aggatgcaac gcaacctgtc
    48121 gaaattgctt ccataacaaa attgattact gtttatctgg tctatgaagc tttggaaaac
    48181 ggaagtatta ccctctccac tcctgtagat atttctgatt atccttatca attgacgaca
    48241 aattctgaag ccagtaatat tcctatggag gcccgtaatt atactgtcga agagttgctt
    48301 gaagcaactc tggtatctag tgccaacagc gccgctattg ccctagctga gaaaattgct
    48361 ggctcagaaa aagatttcgt cgatatgatg cgggcaaaac tcttggaatg gggaattcag
    48421 gatgccactg ttgtcaatac gacaggtctt aacaatgaaa ctctagggga taacatttac
    48481 ccaggttcta aaaaagatga ggaaaataag cttagtgctt atgatgtcgc tatcgttgct
    48541 cgcaatctca tcaaaaaata cccacaagtc ttagaaatca ccaaaaaacc ttcttctact
    48601 tttgctggga tgacaatcac ttcaaccaac tacatgttag aaggtatgcc tgcttaccgt
    48661 ggtggttttg atgggctaaa aacaggaaca acagataagg ctggagagtc ttttgttggt
    48721 actactgtcg aaaaaggcat gagagtcatc acagttgttt taaatgcaga tcatcaagac
    48781 aataatcctt acgctcgatt tacagctaca tcttccctaa tggattatat ttcttctaca
    48841 tttacacttc gcaaaatcgt tcaacaaggc gatgcctatc aagatagcaa agcccctgta
    48901 caagatggaa aagaagatac agtaactgca gtggctccag aggatatcta tctaatcgaa
    48961 cgtgttggga atcaatcttc ccaatctgtt caattcacac ctgattccaa agcaatccca
    49021 gcaccacttg aagctggaac agtggttggc catttgactt atgaagacaa ggacttgatt
    49081 ggtcaaggtt acatcaccac agagcgccct agtttcgaaa tggtagcaga caagaaaatt
    49141 gaaaaagcct tcttcttaaa agtttggtgg aatcagtttg tccgctttgt taacgagaaa
    49201 ttataaaaaa tcgcgatttt aaaccgcgat tttttgatac aagttcatct tcaaaatcaa
    49261 agaacaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtagatga
    49321 aactgacgaa gtcagtaacc atacatacgg taaggcgatg ctgacgtggt ttgaagagat
    49381 tttcgaagag tataaaatca aattttatcc aactgatccc tccatttcat agctaatcaa
    49441 gcggttcagc tcaactgcgt attccattgg aagttctttt gtaaagggtt ctacaaatcc
    49501 catgacaatc atttcagttg cctcagattc tgacaatcca cggctcatga gataatacaa
    49561 ttgctcttct gaaatcttag atactttggc ttcgtgttcc aaagccactt gcgagttgtg
    49621 aatttcatta aatggaatag tatctgatgc tgacaagtca tccatgataa tggtatcaca
    49681 ttcaatgtgg gaaacagatt tcttagagtt cttgttaaag gtgacttgtc cacggtagtc
    49741 aacctttcct ccacctttag cgatggattt agacacaata gacgagctgg tatgtggagc
    49801 attgtgaatc atcttagcac ccgtgtcttg gtgttgccct gcattagcaa aggcgataga
    49861 gagcatggta ccacgcgctc cttctccatc aaggtaaaca gatggatatt tcatagtcgt
    49921 tttggcaccc aagtttccat caatccactc aacagtggca tccttttgag ccttagcacg
    49981 ctttgttacc aagttataga cgttatcaga ccagttttgg atagttgtat aacgcatata
    50041 agctccgtcc aaagcaaaaa tttctacaat ggcagcgtgt aagctattgc ttgaatatgt
    50101 tggtgctgta catccttcta cgtagtggac gcttgctccc tcatcaacga taatcaaggt
    50161 acgttcgaac tgacctatat tttcgttatt gatacggaaa taagtttgaa gtggaatatc
    50221 taccttgaca ccttttggca cgtagataaa agttccaccc gaccatactg ctgagttgag
    50281 ggctgccaac ttgttatctg tcggcggtac caacttcgca aagtattgtt taaataagtc
    50341 tgggtattcc ttgagtgcgg aatctgtatc tgtaaagata atacctaatt tttggaactc
    50401 ttccttcatg ttgtggtaaa ccacttctga ctcgtactgg gcagaagccc ctgctaaata
    50461 agcacgttca gcttctggaa tcccgatacg ttcaaaggtt tctttaatct tttcaggtac
    50521 atcatcccaa gaacgggctg gtttgtcaga tggtttttgg tagtagatta agtcatcaaa
    50581 gtcaatctct gacaagtctg ctccccaagt ttgcatgggc atttttttga aggtttcata
    50641 agacttcaaa cggaactcca acatccactc aggctcaccc ttagcagcag ataattcacg
    50701 aataacacct tcgttgagtc cttttcctgt cgataagaca ggctctacat cgtcatggaa
    50761 accaaattta tattcaccaa ggtcaattgg ttttggttct actctttctt cagccatagt
    50821 atcctttctt tcttcatttc taataattca taagacaaaa gaaacttgtc ttactgtttt
    50881 tcttgatttt caattgtttt cttaagggca ttccaagcta gggttgcaca cttgattctt
    50941 tgagggaatt tggcaacacc tgacaagaat gccgcgtctc caagttggcc ttgacgctca
    51001 tctttttgcc cttgaaccat ttcagaaaaa atagtcgcca gttctaaaat ttcttgtttg
    51061 gtttttccta aaacggcatc tgtcatcata ctagcagaag cagttgaaat cgtgcatcct
    51121 gaatttagaa aagcaatatc ttccaaacgg tcctctgcat caaacttgac agagaggttg
    51181 atgacatccc cacaagtcgg attgttgaga ctggtttgct cagcatcttc taacttccct
    51241 tggtgatgtg gatttttcga atggtctgct accactgcca tataaaggct atctagttta
    51301 gaaagtgcca ttgaaaaact cctttgtctt ttgtagggca tcgactagtt tgtcgcaatc
    51361 tgccttggta ttgtagatat aaaaacttgc acgagctgtt gctgggactt ccaaatactg
    51421 aagcaagggt tgcgcacaat ggtgaccagc acgaacagcc actccttcat aatccagagc
    51481 cgtcgcaaga tcgtgaggat ggagatcacc taggttaaag gcaataacac ccgaacgttg
    51541 agccaaatcc tgagaaccgt aaatggtcaa tccctcaatt gcctgcagtt ttggatagac
    51601 gtacgcaatc aattcctgtt catgagcttc aacggcatcc ataccaatct tttccagata
    51661 atcaactgca gtcgcaagtc caatagctcc tgccatattt ggcgttccag cctcaaattt
    51721 ccaaggcaat tccttccaac tagcaaattg ctcgtagaca aaatcaatca tctcgccgcc
    51781 aaattctact ggagacattt gctcaagata cttttctttg ccgtaaagga caccgatacc
    51841 agtcggacca gccatcttgt gacccgaaaa ggcgaaaaag tccagatcca agtcctggac
    51901 atcaatcttc atatgaggtg tagattgagc accatccact accataattg ccccaacttg
    51961 gtgggctaat tgagtgattt ccttgatcgg attgaccaca ccaagaacat tggaggcatg
    52021 agctagggaa acaaatttaa ccttatcagt caatttagct cgcaaatcct ccatatccaa
    52081 ggcaccgtct ttaagataga catagacaag ctctgctcca gtctttcgac aagcttcctg
    52141 ccatggaatg atattagaat ggtgttccat tactgaaatc aagacccggt ctccctcagc
    52201 gagaatttcc tcagcaaagc gtgccaccca gttaaggctg gttgtcgttc ctctggtaaa
    52261 gagaacttcc tttgtagagc ctgcattaat aaacttacga atggtttcac gagcagcttc
    52321 ataagaagct gtcgctcgtt ccgctaaggt atggacacca cggtgaacat tggcattgtc
    52381 ctgctcatag taactgttaa tagctttcag aactactagt ggtttttgtg tcgtcgcagc
    52441 attgtccaga tagaccagag gttcatcatt gacaatctga tttaaaattg gaaaatcctt
    52501 gcgaatcgct tctacatcta acataggctt ccccttagcg ttttgacaat ttctcttcga
    52561 tagttgcaat catttcatca cgaacttcct tgactggaat ctccacgata acagatccaa
    52621 ggaaaccacg aacaaccaaa cgctctgcag ttgccttatc caatccacga ctcatgaggt
    52681 aatacatgtc ttctggatca acttgtccga tagacgctgc gtgtcctgca gtgacatcat
    52741 tttcatcaat caaaagaatt gggttagcat ctgaacgcgc ttggtctgaa agcatgagaa
    52801 cacggctctc ttgttgcgca tctgctccct tagcaccctt gatgatgtgg ccgataccat
    52861 tgaaagtcaa agttgctttt tcaaggataa ccccatgttg taggatattt ccgatagagt
    52921 tgcagccata gttagttaca cgagtatcaa tcccttgtac ctgacgacca cttgaaagag
    52981 ctacaacctt aaggtcagca tggctaccat taccaatcaa gtcactatca aaatcagcaa
    53041 cgacatttcc ttcgttcatg acaccgatag cccagtcaat acttgcatcg ttgcctaatt
    53101 taccacgacg gctaatgtag gcagtgacgt tttcacctag acggtcgata gcagcaaact
    53161 tgacttgcgc accagaacgt gcaatcactt ccactgtgat attggcagtt actttgtcac
    53221 ttccttcacc gcgtgactct aaacgctcca gataactaat cttagaattt ttaccagcga
    53281 taatcataat atgcttgtta aacggcacat tgctatcgct atcttggtag aaaattcctt
    53341 caattggctc tgtgatttct acgttatctg gaatatagag tacagcacca ctgttaaagt
    53401 aagctgtgtg gtaagccgcc aacttgtcat catcatactt aacagatgac atgaagaatt
    53461 cttcgatcag ctctggaatt tcttctaaag ctgagtgaaa gtctgtgaag acaacaccct
    53521 gttcagctaa ctcaactgga gtttgttcga aaacagtttg agttcctact tgcaccaact
    53581 tcaagtgatg atctaaagct gtgaaatctg gaacatttgc tgatggctca ttttctgtaa
    53641 tcgttccatc acccagattc caacggtgga atttgacacg ctcaataact ggtaattcca
    53701 aagtctcaat cttgtcaaaa gctttttgac ggagatcagc caaccagctt ggttcagcgt
    53761 gcatttctga aaaaagttta atattttctc tagtcattta cttctcctaa aagatacgag
    53821 ggaattacaa ttcttccttg tagtcgtagc caagttcttc agctaatttt gcgtatcctt
    53881 cacgttccaa acgcgcagcc aattctggac caccagaaag gacaacacga ccttccatca
    53941 tcacgtgtac cacatcaggt gtgatatagt tcaaaagacg ttggtagtga gtgatgatca
    54001 tagcaccaaa accttcacca cgcatggcat tgacaccttt agacacaact ttaagagcgt
    54061 caatatcaag acctgagtca atctcgtcca aaagagcaaa tgttggctcc aacatcaaaa
    54121 gttgaagaat ttcattgcgt tttttctcac caccagagaa gccttcgttg aggtaacgct
    54181 ctgccatttc ttctttcatg ttgagcaatt ccattttttc atctagctta gtaataaact
    54241 cacgaactga aatcttctca tcatcttctt tacccgcatt catagcggca cgaagaaact
    54301 cagcattggt aattccaggg atttctgatg ggtattgcat agcaaggaaa agtcccatac
    54361 gcgcacgctc atccacttcc aactcaagga tgtttacgcc atcaaacaaa acttcacctt
    54421 tagttacttc atagtttgga tttcccatga tagcggcaga aagagtcgat ttacctgtac
    54481 catttggtcc catgatagcg gcaatttctc ctgttttcag ggtcaggtta acccctttta
    54541 aaatttcttt tccttcaatc tcaacgtgaa gatctttgat ctctattact gacatgatag
    54601 ttcctttctt tttcaaaact tttacagtac ttactagaaa aacgtctgat ttccccagaa
    54661 atagagcaaa aattctataa atatactttt ctagtataac aaaaaaaagc ctaaaaggct
    54721 ttgattttgt ctggaagctg agggctagtc tttcctatta aaatgctgat cgatgacatc
    54781 aacgatttta cccatcacat aactgactcg gaaatttcta aagagtaaaa ttgcccaaaa
    54841 ggctgccata atatagcggc cagtcatcca ggcttcattg aaaaaatagg tctcagcagc
    54901 tgtaaatagc gccataataa taaattgttg tttattcata aacttattgt atcatgaaat
    54961 ttttctttag tcttcctcta ccttcacttt atcagccaaa aattcaaatc cttctggaat
    55021 caggctttct tctacttctt tttcagtttg agaagatttg gctttggctg aaaaggctgc
    55081 gcgaacttct ttccattcct ccatggaaat agctaaaatc tcaggtgaaa aacctgccgc
    55141 ctgactgagg atattaccaa acatggtatt gagattgtct cgtttcatag tttgaccagc
    55201 attgaagtta gactcaaaag caagaatagc atggtgttca ttggcagcaa ccggttgaga
    55261 accaactagc agagccttgt ccggcccacc tagactttca attacctctc cccaggcatt
    55321 ctgcaaacga attagatttt gacgtgctaa atcaggattt tcgacggcct cttgtaagat
    55381 agattgcact ttattgcgat cgacacgata gactgttttg cccgtagctg gtcgactagg
    55441 agctggtgca acttgtttag gaaccgcacc tacattagaa agctcttgtt tgagacgggc
    55501 aacttcctgt ctcagcgtag caatttcatt ttcaaccgct cctgatagag ctggttcggg
    55561 cttgatttcc gccaaacgga cggtcatcat ttcagcataa atcttgggct gcaaactaga
    55621 cttaatatct gctaaactca ctgttgctaa gcgaatcatt tcaaacagat ttttttgagg
    55681 aagtgccaaa ttttctacaa agactgaact atgatgagta ttttctcccc ctgtttgaac
    55741 aattaacaag tctcttaaat agtgcaaaag atcggtcaca aaacgagtca tgctcttacc
    55801 attgtcaaaa agaagattca agcaagacaa agctttggga acatcctgtt gagacaaggc
    55861 cgccacataa tcatccaagg ctgataggct aatggtgcca gtaatttctt cagagatagc
    55921 agtcgtcagc tcatttccct gtgtcaaact cagggcttga tccaaaatag acaaggcgtc
    55981 ccgcattcca ccttccgccc gtctggcaat gatttccaca gcctctggtt cagaactgat
    56041 attttctttt tctaagatat agtgaatatg ttccttaata tcctgtgtct taattgattt
    56101 aaactcaaaa cgttgcacac gggatagaat agtagcagga atcttgtgca attcagtagt
    56161 ggccaaaata aagactacat tctgtgttgg ttcttccagc gtctttagga gggcattaaa
    56221 agcccctgta gacagcatgt gaacctcatc tatgatataa accttataac gagcaaggct
    56281 aggcgcatag gtagatttat cacgaatttc gcgaatttca tctaccccat tattagaagc
    56341 tgcatccatt tcaatgacat cttctaaact accgtcagtc actgcttgac aaatatagca
    56401 gttattgcaa ggttcgccac ccacttgatt gggacagttt atagccttgg caaagatttt
    56461 agcaacactg gtttttcccg ttccacgagg accagaaaaa agataagcgt gacttatttt
    56521 ctcttgctcc accgcttgtt taagagtctt agccacaact tcttgaccaa ctaactggga
    56581 gaagttttga cttctatatt ttcgataaag tgcttgatac attaagattt ttcctcaaac
    56641 atcgtaaagt cccatgctgt cttttcaagc aaaatagcga caaattgttc caaataatct
    56701 cgatccatag catcgtaatc ctcaatctct gaagaatcca gatccagaac tccaagtaac
    56761 tgaccattct tcatcatcgg caccacaatt tcacttttag ctagactatc acaagaaata
    56821 tagttgagat aggtcgtcac atctccaaca ataacagttt cctgaaagtg agccgcctca
    56881 ccacaaacac ccttgcctag tgcaatacgg atgcaggaaa cacctccttg gaaggggcct
    56941 aaaaccaatt cctttccatc gaacaaataa aagcctgcaa atacggtatt aggaaaacgt
    57001 gattttatga gagcactggc gttggaaaga ttagccaaaa cattggtttc gccttccaat
    57061 aggaaggaca attcttcatt taacatttga taacgtgatt gtttttctga ttttaacata
    57121 gaactattat atcaaaaaag gagcagagac aaaagaaaaa tcccttgttt agtaaacaaa
    57181 ggattttgtg aattttcaat ttgattaaag ttcgatatca ccaaacaaat cagccattga
    57241 aaatcctgtt tgtgtttctg gaagttcgaa atcacgcttt tcttgacgtc ttggacgacg
    57301 tggacgagca gcacgttttt cttctttttg tccttcttct tgggctggac gttcttcaag
    57361 agctttaata gaaagtgaca cgcgttctgc atctgcgtta acttcaagaa ctttaacttg
    57421 aacttcttga ccaactttaa gagcttcttt tggattttca atccgtttgt gtgaaatttg
    57481 tgatacgtga acaagtccat cgatacctgg caatacttca acaaatgcac cgaagtcagt
    57541 caaacgttta actgttcctt ctactacatc acctttagcc aatttttgct caacgccatc
    57601 ccatggtcct ggtactgttg ctttaagtga aagtgataca cgtccttctt cttcgttaag
    57661 atcaaggatt ttcacttcaa tttcttcacc aacagttaca actgattttg gtgatacgtt
    57721 acgttcatgt gacaattcag tcaagtgaac caatccgtca acaccaccaa ggtcgatgaa
    57781 agcgccgaag cttgtgatac gagcaacttt accagttaca acatcaccaa cagccaattt
    57841 accgaatact tcagcgcgag ctgctgcagt agctgcttca acaacttcac gacgtgaaag
    57901 gatgaagcgg ttttctttag cgttaacttc tttgatttta gtatcaaatt cttgacctac
    57961 aaaacgctca gcgttacgta cgaaacgagt atccaacatt gaagctggga taaatccacg
    58021 aacaccttca aattctactg aaagtccacc tttaacggca cgcgttcctt taacagtaac
    58081 aacttcttct tcgcgaccaa caagtttgtc ccatgctttg cgagcttcaa ggcgtttttt
    58141 agatacaagg tatgtaactg tatcagtatc tttaccaact acttgacgaa gtacaagaac
    58201 atccaatact tctcctactt taacaaagtc attgatatct gcatcacgat cgtttgtcaa
    58261 ttcgcgaaga gtcaagacac cttcaacacc agttccagag attgcaacgt tagcttgagt
    58321 cgcatcaact gtcaatactt cagcactaac aacatcacca gtctcaactt gactaacgct
    58381 atttagcaaa tcttcaaatt cgttcatcta aaaaatcctc caacaatcaa gtttttctta
    58441 aacttgacat acttataatt tttttcctaa gcacccgcaa ggacatgttc atatcattca
    58501 cgtctttcaa ttataaaaat aaaataccct aagatatttt gctttttatc ttgattatta
    58561 cctaagaact ggggtagctg gattcgaacc aacgcatgag ggagtcaaag tcccttgcct
    58621 taccgcttgg ctatacccca ttaatgaaat ggagagagag ggattcgaac ccccgaaccc
    58681 gaaggagcgg atttacagtc cgccgcgttt agcctcttcg ctatctctcc tacaatcaac
    58741 atggactatt atatcatgaa aatttcaaaa aaacaagact tattttgcta aattataatt
    58801 ttcaatcaaa atttccacag ttttttccaa ttttttataa aaactatcga cattcccatt
    58861 ctttataatg gcaaattgtc cgtctaattc ggcaatttct ccgataactt ttttaccgat
    58921 agtcaatgta taaccttcaa aactgtcttt accaacatta actttggcat ccgctacttg
    58981 aatttcgatt tttttatctt tcttgctcat ttcatacctc tcttcacttt ttctatttta
    59041 caagaaaatc ctaaaactag caagaaaaaa ctctatatca ggcttctctg atatagagtt
    59101 ttatgtaaac aacctcaatc gatttagcat agttaatagt tagtaaacaa gcataattga
    59161 ctatcctttt taggttatca gtgagtctca ccgcctacta actgcaaatc cttatctttg
    59221 tagtctacaa tagcttcaat agctacctct atgcctctta caatatcaca tagactcatt
    59281 cctgcagtat tcggcttatt tactacttgt tccatcatat atggaatatg catgaaacct
    59341 gctctcatat tagggaattt tttatccact aaataaagag cttggtacat caaatgattg
    59401 caaacaaagg ttcctgcact attggataca actgccggaa gtccctgttt tttgatagct
    59461 tgtaccatcg ctttgatagg taaactacta aaataggccg atgctccatc aatacgaatc
    59521 ggtgtatcaa ttggttgatt gccttcgtta tcaggtatgc gagcatcatc ttgattaata
    59581 gccactcgtt caggtgttaa gccggttctg ccgcctgctt gtccaataca aagtacagca
    59641 tctggttgat atcgtaatat ttctgcctct aaaacttctg acgacttata aaaaaccgtt
    59701 ggaatttcta cccagcgaac ttcagcccca ttaatctcag atggtaataa ttttacagcc
    59761 tccaaagctg gattaatctt ttcacctcca aaaggattaa aacctgtaac caatattttc
    59821 attttatttt cctttactaa aatgcgagaa agtacattaa gaatatgtga ataacaatca
    59881 ttactagagc aacacctgct tgagccttta taacgccatt ctgatctttc atatccatca
    59941 atgctgctgg tagagcgtta aaattagcag ccattggggt caataaggtc ccacaataac
    60001 ctgctgtcat ggcaagagca ccagccacaa ttggattagc tcccagagca aatacaaagg
    60061 gaactccaac acctgctgta ataacggtga atgctgcaaa agcatttccc ataatcattg
    60121 tgaatagaac cattccaaga acataggcca aaactcctat aaagcgacta tctgaaggaa
    60181 caataccgct aatcagatga gagataacat caccaacacc tgctacagta aaaatagccc
    60241 ccaaagcccc taataattga ggaacaatcc cacttgttga aacttgctga gtcattcgat
    60301 tattttctga taacagactc ttagggtgac tattggtaat cacaagaaca gaaattgtag
    60361 caaacaaggc ggcaaggcta atcgaaatct tgctaaattc tggaatcatt tgcgctaaga
    60421 ccaacgcaag tattgccatc agcataactg gaataaaaat tttatttttc aacctgttag
    60481 attcaatatt ggctttcatt tcatctaagg atggcaaggt tccgatacgg acttgcttaa
    60541 acaatgttaa cagcgataat aggattacaa taataccaat actcatattt ggcatatagg
    60601 aaccacctat aaacgtaata gacaatagag tccaaaatgc agatgtccca agtcgaactg
    60661 ggtttgtttt atctttataa ctacaatagg ctgtatggag aaattgacaa ccaatcacaa
    60721 tataggtcaa ctctaatagt tgctttgcca actctgtcat ttttgttctc ctcccctagt
    60781 cttttttgat atcaattttt tatcaaataa ataattgtaa atccctacta caataagtgt
    60841 tataacagca acaataatag atgtagaagc aatccctgca taattgcttt catagcctaa
    60901 ctgatctaat gttcccccta tcaagaggac tcccccagca cctacaaacg tattttgagc
    60961 aaagaaattt ccaaaatttt cattcgctgc cgcacgcgct tttattgtct catcttcaac
    61021 ctctgttaac tttctaccta attgagactc tgcagctgct tctcccatag gttgaaccaa
    61081 aggtctgaca aactgagggt gtcctcctag acgaattgaa aagaaaccag ctaactctcg
    61141 aataaagaaa taaactgtat agaagtttcc aactgtcaga cctttaatct ttcgaatcaa
    61201 atcgattgat cgttgcttga gtccaaaggt ttctgacagc cccacaagag gcaaggtaac
    61261 cataaaaatc gtgagcactc gctgattgct aaattctttt cccaaaatct ccaaaaattc
    61321 aacgagagaa acacctgaaa ctaaagctgt aaccaaacca gctaagacta ctgttgcaat
    61381 tgtatcaaat tttaaaataa aacccacaac aatgattgct attcctatta atctaatcca
    61441 ctccatatca aactccttta tattcaaaat gacagtattt taaaaatttt atcaagatca
    61501 ataccattcc ttatttaatg tatttttcta gttctttttg gtatttgcta ttggattcca
    61561 atttttcttt ttgccatttt ttaaaaacct cgttatattc ttttgttgta acaatatctt
    61621 tttgcaattt cattccttta aagatatatg gttccccctt aataccaact tgtgagtatg
    61681 gttttgagaa tggtactacg ttacttacaa ctggaaaacc accagatgaa gctgttggca
    61741 tcaataatga actatctgtc gaccaagctt gagctttggc atatttttca tatctcttct
    61801 ctaggtcagt ggtctcagaa acagcatctt ctaacaattt cttatattta tccaaaccag
    61861 gtttagctac aacatcctta tcttttcctt tcgtaatgcc aaggtgtttc atggcagaac
    61921 cagattttgg atccataata ttcaagtaag acgctggatc ttgatagctt ggagcccatc
    61981 ctgtactgtt caaatcatag tctttttgag aaggagcaac attgccgtat ttatcatttt
    62041 ccatcaaacc atcaataaca tttccaataa cgtctgtcct cgatgttcga gtcgctatac
    62101 tgtagcccaa tgatgctgga tctactgcat agacataaga aaatgttgtc ggtgcatctg
    62161 cttctttatc agtttttcca caagccacta aaatagctga cgtgctcagg accactcctg
    62221 ctgttaagag ccactttttc tatttcataa aaaatctcct ttggtttatt ttaatctact
    62281 tttacaatcc aaccttctgg cgcttcaata tcgccaaact gaatacccgt caattcatta
    62341 tataatttac gcgtcacagg acctacttct gtttcactat agaatacatg gaaatcatca
    62401 ccatgttgaa tacctccaat tggagaaata accgctgctg taccacaggc acctgcctct
    62461 acaaaacggt caagattatc aattggaaca tcaccctcaa taggagttaa tcccaagcga
    62521 tgttctgcca aataaagcaa ggaatacttg gtaatagatg gcaagataga tggactcaat
    62581 ggtgttacaa attcattatc agctgtaatt ccaaagaagt tagctgatcc gacttcttca
    62641 atctttgtat gagttgatgg gtccagatag ataacatctg agaaatgacg tgacttggcc
    62701 atttttcctg gtaagagact tgcagcatag tttccaccaa ccttagccgc acctgtacca
    62761 tttggtgctg cacggtcgta ctcatcctga atcaagaagt tggttgggac caaaccacct
    62821 ttaaagtaat ttccaactgg catagcaaag atggtgaaaa tgtactcttc tgccggtttt
    62881 accccgataa tatctccgac accaatcaaa agagggcgaa gatataaggt tccacctgtt
    62941 ccgtatggtg gtacgtattc ttcattcgca cggacaactg ctttacaagc ttctacaaac
    63001 atgtctgtcg gaacttgtgg catcaagaga cggtcacatg tacgttgcag acgtttagca
    63061 ttttcatcag gacggaacag ttgaacactg ccatccttag tacgataagc tttcaaacct
    63121 tcaaatgctt gttgtccata gtgaagactt ggagaagact ctgaaatatg caaagttgca
    63181 tcctctgtaa gctctccttg atcccattgt ccatttttga aatgagcaag atagcgataa
    63241 ggtaatttca tataggaaaa accgaggttt tcccaatcaa tcgttactgt catattccac
    63301 tccttattct aaaaacctat ttcttatatt ctacactatt tttctaaaat agcaagtata
    63361 ttttgtaatt ttcagaaaat ttctccaata aaaaccagct cttagaactg attcttcatt
    63421 tcacttattt atcttcagta actacttcct gaagataagc gtcaaaaact tcttcatctg
    63481 aaatcgtgtc agaaatgaag cttccattgc tagtgcgttc tgacaagttc aagtcttgca
    63541 atcggctttc atagattgtt cctttattgg attggacaag cagagtttgg tcgttcacat
    63601 ccacttccgt actgaagaaa tcgccaacaa atccttgctc tgcaactgct cctgccaaga
    63661 agacacgatg cggtttgttt ttcaactcac gcaagacttg taatcctcgt ttggcacggc
    63721 tggttgctag aatttcctca atggaaacac gtttcaagct tccacgctgg gtcaagaggt
    63781 agaaggacga agtattacag ataaagccag attggaggac atcatcttct ttcaaattca
    63841 tagccttgac acctgctgcc ttagcaccga caaccggaac ctcttcgata ttgaaacgca
    63901 gggcataacc attttgacta accaagacaa catcatctag tttaatcgga gccactgcta
    63961 caatctgatc tgtatcgtct ttgagcttag catacttgac agacttagat ctataggtcc
    64021 gccatggagt gaattctttt cgctctaccc gtttgatttg accaaggcga gtcactgcaa
    64081 agtaggttgt cgcatcgtca aactgatcca gtacttccac ataaaggatt tcttcattcg
    64141 tttcaaagtt tgtgatggtt tggctcagat gctctccgat gtccttccaa cgaatatctg
    64201 ccaactcatg gattggtctg tagatgacat ttccaagact tgtgaacatc aagaggtgct
    64261 gggttgtctt ggcagattga acaaaaatca aacggtcatc atcacgcttg ccaatttctt
    64321 ccaaggtgga agccgcaaag gaacgtggac tggtacgctt gatgtaacct gccttggtca
    64381 cgctgacgta ggtatcttcc tcagcgataa gactagctgt atcaatctca attgctttcg
    64441 cagtgtcttc taaagaactc aaacgaggag ttgcaaattt cttcttgacc tcacgaagtt
    64501 ctttcttcat gagattgtac atagtccttt catcaccgat aatagccgcc agcatagcaa
    64561 tcttctcacg aagctctgct tcttcttcct gcaagacaac cacatcggta ttggtcaaac
    64621 ggtacagttg caaagttacg atagcctcag cctgttcttc cgtaaaatca tagctaactt
    64681 tgaggttttc cttggcgtcc gccttattct cagaagcacg gataagagca atgacttcat
    64741 ccaaaatcga aatcacacga atcaaacctt cgacgatatg gagacgcttc tcagcctttt
    64801 ctttgtcaaa gcgtgaacgc gccaaaatca cttctcgacg gtgagcgatg tagctagaca
    64861 ggattggaac aatcccaacc tgacgaggtg tgaaattgtc aatcgccacc atattaaagt
    64921 tgtagttgat ttgtaggtcg gtgtacttaa ataagtagtt gagaacaagc tcagtattag
    64981 cgtctttctt aagttcgata gcgatacgaa gaccatcacg gtcagactca tcacgaacct
    65041 cagcaatccc agctaccttg ttattaacac gaacatcatc gattttcttg actagattgg
    65101 ccttattgat ttcataagga atctcagtaa taacgatttg ttccttacca ccttttagct
    65161 tttcaatttc agtcttggaa cgaacaacca cgcgcccttt cccagtctca taagctttct
    65221 tgatttcatc acgaccctga ataatagccc ctgtagggaa gtctggtcca ggcaagaatt
    65281 ccatgagttt atcaatcttt gcagttgggt ggtcaatcat gtaaactgca gcatctatga
    65341 cctcagctaa attatgggga ggaatgtctg tggcataacc agccgaaatc ccagtcgaac
    65401 cattgaccaa gaggtttgga aaggctgctg gcaagaccgt tggttctttc tccgtatcgt
    65461 caaagttcca tgcaaaagga actgtatttt tctcgatatc ctgaagaagg taacctgcaa
    65521 tttcagacaa acgtgcctca gtataacgca tagccgcagg aggatctccg tccatagaac
    65581 cgttattacc gtgcatttca actagaatct cacgattttt ccagttctgt gacatacgaa
    65641 ccatggcatc atagatagaa gaatccccgt gtgggtggaa attccccatg atgttcccga
    65701 ctgacttggc cgacttacgg tagctcttgt caaaagtatt gctatcctta ttcatagaat
    65761 aaagaatacg gcgctgaacc ggcttcaacc catcacgaat atctggcaaa gcccggtctt
    65821 gaataatgta cttggagtag cgaccaaagc gctctcccat gatgtcctcc agggacatgt
    65881 tttgaatgtt agacataaga tacaaagccc ataaaatacc aagtgaaaat agaaaattct
    65941 tgaagtaagc aaactcacaa gagaatttat ctttttcaca cagtgtctag ggcgtgttca
    66001 actcctttca aagaatgtag agtaggtttt tatgcagtaa aagatatttt acgggaattc
    66061 ctcccgtgtt cagttacgat aagtaaccaa actatcctgt ttgtattttt caatatgaaa
    66121 atctggtttt ccaaaattag tcttagtttg tgtcttagcc gctcccttaa gcgcctcttt
    66181 gagataagca ctcatagcag attcttcatt aataatcctg caattttttc aaaccaagat
    66241 tttcaaactg ctttttcaca tagtcattca catccgactc taatttccag tttactaaca
    66301 tattattttc tttcattaaa acactgtcgc ttcttctagc gtaaacttga cattatcttc
    66361 aatccattta cggcgtggtt ctaccttatc tcccatgaga acattgacgc ggcgttcggc
    66421 gcgcgctaaa tcttcaattg tgacacggat gagggtacgt gtttctgggt tcatggttgt
    66481 ttcccagagc tggtccgcat tcatctcacc aagtcctttg tatcgttgga gggtagcgcc
    66541 tttaccgaac tgtttacgga gttcttctag ttctccgtcc gtccaagcgt aggccacttc
    66601 ttctttcttg cctttacctt tggacatctt ataaagaggt gggagggcaa tatagacatg
    66661 acctgcctcg actagcggac gcatgtaacg gtagaaaaat gtcaagagca aggtctggat
    66721 atgggcaccg tcggtatccg catcggtcat gataatgatc ttatcatagt tggcatcttc
    66781 aatagagaag tctgctccaa cacccgcacc aatggtataa atcatggtat taatctcttc
    66841 atttttgagg atatccgcca tcttggcctt ggctgtattg acaaccttac cacgaagagg
    66901 tagaatagcc tggaacttgc ggtcacgacc ttgtttggca gaaccaccgg cagagtcccc
    66961 ctcaactaga tagagttcat tcttagcagg attcttagat tgggctgggg tcaatttccc
    67021 agacaacaag cccttatctt tcttgttttt cttcccattt cggctctcat cacgcgcctt
    67081 acgtgctgct tcacgagcat cacgggcctt gatagccttg cggatgaggt tagaagctaa
    67141 ttccccattt tccataagga aaaaggtcaa cttatcagcc actattccat ccacaactgg
    67201 gcgagctagg gggcttccta gtttatcctt ggtctgtcct tcaaactgca agtgttcttc
    67261 aggaactaag atagaaagaa cggccgctag tccctcacga tagtctgaac cttcaaggtt
    67321 tttatctttt tccttgagaa gacctgtttt acgtgcatag tcattcatga ccttggtaat
    67381 ggcagacttg agtcctgtct cgtgcgttcc accgtccttg gtgcgaacgt tattgacaaa
    67441 agatagaatg ttatctgaga atccgtcatt gtactggagg gctacttcca cttgaaaacc
    67501 attgtcttcc ccttcaaagt aaagaactgg cgtcaagatt tccttatctt cgttgagata
    67561 agaaacaaaa tcttgtactc cattctcata gtggaactca atcgcttcat ctgttcgctt
    67621 gtccgttaaa gacaaggtca catttttcaa gagaaaggct gattcattaa ggcgctctga
    67681 aatggtattg tacttgaaat ctgtcgtaga aaagatagtc gcgtcaggca taaaagtaac
    67741 tttggtgcct gttttagact tgggtgctgt accgattttc ttcaaagtcg tgacaggttt
    67801 tccaccattt tcgaaacgtt gcttgtaaac tgcaccatca cgggtaattt caacttctaa
    67861 ccagttagaa agggcgttaa caacggaaga acccactccg tgaagtccac ctgatgtctt
    67921 atagccacct tgaccgaatt tccctccggc atgaagaatg gtaaagataa cctcaacagt
    67981 tggaattccc atagcgtgca tacctgtcgg catcccacgt ccatggtctt gaaccgttag
    68041 actaccgtct ttattgatag ttacatcaat acgatcacca aacccagaca aggcttcatc
    68101 gactgcatta tcaacgattt cccaaactag gtgatgaaga ccagcgccat cggtcgatcc
    68161 aatatacatc cctggacgtt ttcggaccgc atccaaccct tctagcacct gaatagcatc
    68221 atcattataa ttgttaatat tgatttcctt ttttgacaca aggaacctcc tattcgttca
    68281 tctttactat tctacaggtt ttccaaggat tttgcaaaat ttttctttct ccgatgtgac
    68341 aatttcagca gagattctct gcttttcttt cccaattcat gatataatag gagtatgatt
    68401 acaatagttt tattaatcct agcctatctg ctgggttcga ttccatctgg tctctggatt
    68461 ggacaagtat tctttcaaat caatctacgc gagcatggtt ctggtaacac tggaacgacc
    68521 aacaccttcc gcattttagg taagaaagct ggtatggcaa cctttgtgat tgactttttc
    68581 aaaggaaccc tagcaacgct gcttccgatt atttttcatc tacaaggcgt ttctcctctc
    68641 atctttggac ttttggctgt tatcggccat accttcccta tctttgcagg atttaaaggt
    68701 ggtaaggctg tcgcaaccag tgctggagtg attttcggat ttgcgcctat cttctgtctc
    68761 taccttgcga ttatcttctt tggagctctc tatcttggca gtatgatttc attgtctagt
    68821 gtcacagcat cgattgcggc tgttatcggg gttctgctct ttccactttt tggttttatc
    68881 ctgagtaact atgactctct cttcatcgct attatcttag cacttgctag tttgattatc
    68941 attcgtcata aggacaatat agctcgtatc aaaaataaaa ctgaaaattt ggtcccttgg
    69001 ggattgaacc taacccatca agatcctaaa aaataaaacg ccagttctgt actgacccca
    69061 aacagttaga caattaattt atccgaagga tttagttctg tattgcacag ggctaagtcc
    69121 ttttagtttt atcttaattc gtttattgtt gtagtaatca atatagtcta taatggcttg
    69181 ttccaattgc ttaagcgact gaaacgactt ctcataaccg taaaacattt ccgatttcag
    69241 aatcccaaag aaggactcca tcataccatt gtctgggctg ttacccttac gtgacatgga
    69301 tgcttgaact cccttactct ctaggaaccg atgataagaa tcgtgtcggt attgccagcc
    69361 ttggtcacta tggagaatcg tattctcata gtatttctct gtaaaggcct gttctaacat
    69421 actcttcact tgttctaagt tgggcgaagt tgaaagatta taggcgataa tttcgctatt
    69481 aaagccatct aaaactggta ataagtaaag cttttgagta cttgctggaa tggcaaattc
    69541 tgtcacatct gtgtagcact tttccattgt tttagagcct tcaaattggc cttgaatgag
    69601 attctctgcc ttcttaccaa cgtctccttt attttcgttt ctgtcgcatt ttagcttgta
    69661 aattgagtac ttttatcaag ccttgaactc ttttatgatt taccagataa gcacgatttc
    69721 ttagttctaa atgaatacag cgataagcat aatttccctt gtgttcgata aaaatggatt
    69781 gaatttcagc tttaagctct tgatccttat ctgttttgtc tagctgtttc aagtgatagt
    69841 agtaggtcga acgagctagt ttaatggatt ttagaagaag atctaacgaa aactcagtca
    69901 ttaattcttg aacaatttct gtctttcttc tttctctttt tcctccttca atcggagttc
    69961 tcttaacttt tttaggatgg cattctccgc tctcaggtac tcattttctg attgaagacg
    70021 ttctaattct gtcctctctt caggtctcgt ttttggatta cgtcccattt taggtactct
    70081 ccctcttggt ttctcaacaa tagtataccc gtttttcctg tattgtgcta gccagttaag
    70141 aagtatcgta cgacttggga gaccgtattc aagagaaact ctatctttag tccagccttc
    70201 atgtcagact ttattactca tttcttgttt taaatcagga gaatagtaac gattttttcc
    70261 ttttttgacg aactctattc cgtaacgatc aatcaattta atcatgtacc taatattaga
    70321 attatttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt ttctaagttc
    70381 atagatctga actttatcat cataagttag tttcataata aaaacacccc aaaagttaga
    70441 ttttttctgt ctaacttttg gggggcagtt cagtcattgg actgacgttt ttttgtatgc
    70501 ttattttgat ttgatgtagt tgataccatc tgcttttggt gcgactgctt ttccaaagaa
    70561 ggctgctaag acaagaattg tcaaaacata aggtgcaatt tgaagataaa ccgctggcac
    70621 tccttgtagg aacggcaatt gagaaccgat aacagccaaa ctttgtgaaa gtccaaagaa
    70681 gagactagaa agcatagcac cgattggatt ccatttccca aagatcatcg cagcaagggc
    70741 gataaatcca ggtccaacaa tagttgtcac tgagaagtta actgagattg attgcgcata
    70801 aatcgctccg ccaattccac ctagaaaacc tgaaataata atccctaaat atctcatctt
    70861 gtagacgttg attcccaagg tatccgctgc ttgaggatgt tcaccgacag agcggagacg
    70921 aagaccaaat tgagtcttaa agagaataaa ccaagcaagg aatgagaagg caatcgccag
    70981 ataaccaagt agactagttg acttgaagaa gatatcacca atcactggga tatttgccaa
    71041 gactgggaaa tcaaagcgtc caaaagtttg acttaggttg tcggtttgtc ctttgttata
    71101 aagaacttta actaagaaaa cagccaaggc aggcgccatc aagttcaata ccgtaccgct
    71161 gacaacatgg tctgcacgga aatgaaccgt cgctgctgcg tggatgatag agaaaacact
    71221 accaaccaat cctgctacaa gcaaggatag ccatggagtt gctgctccaa attgttctgc
    71281 aaattcaagg ttaaagacaa ctccagaaaa ggcacccata accataattc cttcaaggcc
    71341 aacgtttacc acaccaccac gttcagagaa aacaccaccg atacttgtaa agatgagagg
    71401 tgctgagtaa atcagcatag aagacaccaa gagggggagc aaggttataa tagacatctt
    71461 tacttacctc ctttaacttg ttttttcggt ttgacaaagc gttcgataag gtaatgaaca
    71521 ctgacaaaga agataataga cgctgttaca atgctgacaa gctcagatgg tacctgcgcc
    71581 gcattcatac caggagcccc aacttggaga acgccaaata ggaaggctgc aaagagtata
    71641 ccaattggtg agttggccgc aagcaaacta accgccattc cgttaaatcc gatagctaat
    71701 gacgaacctt gaacatagac gttctggaag gttcccaaac cttcaacaga tccaccaaga
    71761 cctgccaagg cacctgaaat aatcatagat aggataatag tccgcttggc agaaatacca
    71821 gcatattctg aagcatgtgg attaagacca actgcacgga tttcaaaacc aagagttgtt
    71881 ttcttgagca tgaaccaaat aactgcaacg gcaatgatgg caaagaaaat accaatattc
    71941 atccgtgagt taccagtcaa ctcagccaac caaggtgtct gataggttgc attagcccca
    72001 acacgaatgg tcgaatctgt actttgcatg aagtctttag ggaaagcatg gataaaggca
    72061 ttccctacat acaagacaat gtagttcatc atgatggtta caataacctc tgacgtccct
    72121 agataggccc taagaatacc tggaatcgct ccgacaatcc caccagcaat caaggcaatc
    72181 acgatggttg ctagaatcat caagggacgg ggcatatctg gatgcaacag ggcaaaccaa
    72241 ccactgagaa tccaacctgc caaagcctga ccaggaagtc cgacgttaaa gaaaccagct
    72301 cgactggcaa ccgcaaaacc aagaccaatc aagaccagag gacccatagc acggaagatt
    72361 tctccaatcc cacgcagact gccaaaggct gtatagaaca attcttcgta gccccaaata
    72421 gcatcataac cgaagatcca catgacaatg gctccgagta aaattcctag gaatacagaa
    72481 atcaagggaa ccgaaatttg ttgtaatttt ttagacatca ctcttctcct ttcccaagtt
    72541 tccaccagcc atcaagacac caagtccttg tttattggtt gtttctggtg atacaatacc
    72601 ttgaatctta ccatcgtgga taacggcaat acggtctgag acgtttaaaa tctcatccaa
    72661 ttcaaagctg acaacaagga cagccttgcc attatcacgc tcttcaatca agcgtttgtg
    72721 gatatactca atggcaccga catccaaccc acgagttggc tggctaacga taaggagatc
    72781 aggatctcga tcaatttcac gagcaataat tgctttttgt tgatttcctc ctgagagtgc
    72841 agctgcagga actaattcac tggcagcgcg aacatcaaac tcttccatca gctttttagc
    72901 ataagaagta atatttgaat aattcaaaat tccattttta ctatatggtt ctttatagta
    72961 ggtttgaagg gcaatatttt cagatatcat catttccaaa atcaagccat cacggtgacg
    73021 gtcttctgga acgtgcccaa cacttagttc tgtaatctga cgtgggtgca agcctacaat
    73081 tgaatctcct tttagctcaa tgctaccaga ttcaacctta cgaagacctg taatggcttg
    73141 aatcagttca gactgaccat ttccatcaat ccccgcaata ccaacaatct ctccagcacg
    73201 aacatccaag gacagatttt taacagctgg aacaccacgg ttttcattga ccaccaaatc
    73261 tttgatagac aaaaccactt cttttggttt agaggcttgc ttctctgttt taaaggaaac
    73321 agaacgtcct accatcattt ccgccaaatc agcattggta gcccctgcaa tttcaacggt
    73381 ttcaattgat ttcccacgac ggataactgt aacacggtca gaaactgcgc gaatttcatc
    73441 caatttgtgg gtaatcaaga taattgattt tccttctttg acaagatttt tcataatagc
    73501 catcaactca tcaatttctg atggagtcaa aacagccgtt ggttcgtcaa agataaggat
    73561 atcagccccc ctataaagtg tttttaaaat ttctacacgt tgttgggctc caactgagat
    73621 atctgctacc ttggcagaag ggtcaacagc taagccataa cgttcagaaa gagccttgat
    73681 ttctttgcta gctccagcga tatctagcac accattttta gtcaattcac tacctaaaat
    73741 gatgttttca gccactgtga aggcttcaac caacataaag tgctggtgaa ccatcccgat
    73801 tcccaagcta gctgctttag atggggagtc gagattgaca acttgaccgt tgaccgcgat
    73861 ttcaccacta gttggttcaa gaaggcctgc taacatgttc attagcgtgg acttaccagc
    73921 cccattttct cctaaaagtg catgaatttc accttttcgt aggtgcaagt tgattttgtc
    73981 gttagcaaca aatccaccaa acaccttggt aatatcacgc atctcaatga cattttcgtg
    74041 tgccatgtgc tcttcctttc agagtcttat tttatttcaa taaaacttgc tagtttgtct
    74101 agtagcaagc tttactgaga caaaatgact ttgtctcaac tcttaaaaaa gcggcccttg
    74161 gccgcttcct aagaaatgac ttccatccat tatttttcag gaacttttac gcttccatca
    74221 aggattttag cttttgcatc ttcgacagct tttttacctt cttctgaaag gtttgttact
    74281 gccaagtcaa cccctttatc cttcaatgag taaacgatca cttgaccgcc agggaattct
    74341 cctttttctg ccttgttaga aatatctttt acagttgtac caacttgttt caaagtagat
    74401 acaagaacaa agtttgattc tttgccatct ttagaagtgt atttaccttc tgcttcttgg
    74461 tcacgatcaa caccgataac ccaaactttt tcattttcag gacggctttc gttgagagat
    74521 tttgcctctg caaagacacc tgcacctgta ccaccagcta cttggtaaac aatatctgca
    74581 ccggctgcgt attgtgcggc tgcaattgtt ttacctttag ccgcatcacc aaatgaacca
    74641 gcgtagtcaa cttggacttt gatagatggg tctactgacg caacaccagc cttgaatcct
    74701 gcttcaaaac gagagataac ttcagattcg ataccaccta caaaaccaac ttgttttgtc
    74761 ttagttgttt ttgctgcagc cacacctgca aggtaacctg actcattatc agcgaaagtt
    74821 acgctcgcaa cattcttttg gtctttaatc acatcatcaa tcaagacata gttcaagtca
    74881 gtgtgttctt ttgctgcatc tttaactgca ttattaaggg caaaaccaac accgaagatt
    74941 aggttgtaac ttccagccgc ttgttgcaag ttgttagcgt agtcagcttc acttgttgat
    75001 tggaagtaag tgaaaccgtt atcttttgaa agattgtgtt ctttacccca agcctgcaaa
    75061 ccttcccaag ctgattggtt gaatgatttg tcatcaacac caccagtatc agtgacgatt
    75121 gctgcttttg tcttcacatc agaagatgaa gctacgttac gagaagagcg gttaccacat
    75181 gcagcaagtc caactgctgc cactgcaact aggccaagac ctagccattg tttcttgttc
    75241 attactgaac ctcctaaata agatgtgcaa cgatgttgca agtatggatt ggttggccac
    75301 aaggaccgtg ccactcagag agcgactcag actagtttaa gtctgtaaaa gagtatggaa
    75361 gtaattcccc gaccgtcatc tcgaccgtcg atttatcttt tgcgactaag gtcactttta
    75421 gatcttgttc aaaaaattca gccatcactt ggcgacaagc accacatggc gagatcggtt
    75481 tttcagtttg accatagaca atcaattctg aaaattctct ttggccttca gatatagcct
    75541 taaaaatagc tgttctctca ccgcaattgg tcaaaggata gctagcattt tcgatattca
    75601 ctcccgtgta aacacttccg tctttggcta ctaaaactgc tccgatagga aagtgagaat
    75661 aggggacata ggcatgtttg ctggtttcaa ttgccagttc aatcaactca gtagtcgcca
    75721 tctgccaatt ctccttttaa aatagctacc ccagctgacg ttccgatacg ggtcgcacct
    75781 gcttcgacaa aggcaagagc atctgcataa gaacgagctc caccagcagc cttgactccc
    75841 atatcagatc caactgtttc acgcattaat gtaacatctg ctatcgtagc accaccagtt
    75901 gaaaaaccag tagatgtttt aacaaagtca gccccagctt tttgggccaa ttggcaaaca
    75961 acaatttttt cttggtctgt cagaaggcaa gcttcaataa tgactttcac taacttatca
    76021 ccacttgctt ccactactgc gcgaatatct gactcaacca aggctaaatt acctgatttg
    76081 agagctccaa cattgatcac catatcaatc tcatcagccc cattttggat agcttctttt
    76141 gtctcaaatg ctttcacggc tgaagttgtt gctcccaaag ggaaacctac tactgtgcaa
    76201 accttaacat ctgtgccttc aagtcctttt ttagcatgtt caacccaggt cggattaacg
    76261 caaacactgg caaagtcata ctctctagcc tcagacaaca aactatcaat ttgttttttc
    76321 tttgcatctt gttttaaaag cgtatgatct atatatttat ttaatttcat ttcggttttc
    76381 cctccattta ggagatgatt tctacaattt cacggatttt ttttacttca tcacttattt
    76441 taacacattt ttggaaatct gtaactagtt gaggtggaat tttttcattt gtgtatactt
    76501 ttgcaacaat ttcacccttt tgaacggagt ctccaatctt cttttcaaaa acaattcctg
    76561 tttcatagtc caaggcatca gacttaactg cacgaccagc acccagcctc atggcataaa
    76621 gaccaaagtc catagctgga agagctgaaa tgacacccgt ttcctgagca gggatttcca
    76681 ccacatgagc tacatttaca ggacgataga ggtcttccaa gtctccacct tgggcttgca
    76741 ccatttcctc aaacttagcc agtgcttgac cattctcaag atgttggcga acttcttcaa
    76801 cagttttgtt aacatttgcc aaactaagca taatttgagc caattcacaa ataaagtggg
    76861 taatatcctg acgtccttga ccttgcaaaa tctccaatgc ttcaaggatt tccagacgat
    76921 ttccaatcgc tcgtcccaaa ggctggctca tatccgtaat cactgctact gtcttccgtc
    76981 caacaacctt accaagatct accatagttt gagccaactc acgcgcctca tcaaccgtct
    77041 tcatgaaggc accctcaccg acagtcacgt ctagcaaaat agcatccgcc cctgccgcaa
    77101 ttttcttgct catcaccgaa ctcgcaatca aaggaatcgt gtcgacagtt gcggtcacat
    77161 cacgaagggc atagagaagc ttatctgctt tgaccagctg gtctgattgc ccaatgacag
    77221 atactccaat atcctgaacc tgacgaataa aatcctcttg actacgttct acttgatagc
    77281 ccttaatgga ctccaattta tcaattgttc cgcctgtatg gccaagacca cgaccactca
    77341 tttttgctac aggcacaccg aagctagcaa caagaggagc tagaatcaag gttaccttat
    77401 cgccgacacc accagtagaa tgcttgtcaa ctttcacacc atcaatggct gacaggtcaa
    77461 actcttgccc agtcttaacc atattcatcg ttaaatcaga aatttcacga gtcgtcattc
    77521 ctttaaaata aacagccata gcaaaggcag acatctgata atcaggaaca gttcctgaca
    77581 catagccttc taccagccat tcaatttcac ttgaagtcag ttcttgaccg tctcgttttt
    77641 tttgtattaa atcaactgct ctcattcttt cacacttcta aggatatagt atcctttgtc
    77701 ttttttaagg atttcacaat taccaaacac atcctccatc ttggacttag cacttggagc
    77761 cccttgtttt ttctggatga cgattgtcaa atccccacca gtttccaaga aatctttact
    77821 tttctcaatg atttcatgaa cgacttgctt gcccgcacgg ataggaggat tggaaatgac
    77881 atgatcaaaa tgtccttcaa cttgttcata gatgttggac tggaaaatcg tcgcttttgc
    77941 attatttttt tcagcatttc tccgagctaa atctaaggca cgagtgttga tatcaaccat
    78001 agtagcctga actccataag ccttagctaa ggacaaaccc aaaggtccgt aaccacagcc
    78061 tacatcaagg acagtttctc cttggttgac ctcaagacac ttgagcaata gttgacttcc
    78121 aaagtcaact attttcttgc taaaaacacc cgcatccgtt aaaaaggtca ttttttgtcc
    78181 caacaactct actctcaact cataaatgtc gtgagcagcg tcaggatttt ctgcataata
    78241 cattttactc atgacactat tttaccataa tttgactcaa attgtaaatc gtttacaaat
    78301 tgataataaa acgaaaaaga ccgaagaaag cgagtcacga agccattttc ttcaatctct
    78361 ttcaacactt ataaataata aaccatttag aactataaat atcacagtcc agataaaaac
    78421 aaaaagttta tcatctataa tcaggcagat tattatttct attgcttaac cttaaaatac
    78481 tttattatca acaaaattcc caacaaaatg tttagataaa agcccaactg atacgtttgt
    78541 gtcaggattt ccaaacttgt ccaaagtcgt atcaaatctt ctagtgacat gcggaagaaa
    78601 taaccctctg tcgcaatcca taggactaaa aagcaataac taccagcagc aatccatttc
    78661 gcccatcgtt tttttagtaa gaaagcaatt aaaaacgaac agataaagac agctgttaca
    78721 atagcatgtt ccatcaaaaa agtaaaaccg taataggttt ccacaaagca tctaccatta
    78781 tctgcattgg ctccttttat aaaaggtaaa gcaaaactta aaataaaaca gagttccaat
    78841 atgtaacgtt ttaagatttt catagtacac ctcctataag ttgtgaacta aaaagccccc
    78901 tttataagct tataaatcag tagaatctat ctcctatttc atcaataaat tgatcgctta
    78961 tattatatat cattgactta caacattcaa gaaaccgctt tattttttta gctttttatg
    79021 gtatgataga taaaatacct aggggaaaac aaatgaccaa cgaattttta cattttgaaa
    79081 aaatcagccg ccagacttgg caatctttac atcgaaagac aacacctcct ttgacagaag
    79141 aagaattgga atctatcaag agttttaatg accaaatcag tctccaagac gttacagata
    79201 tctatctccc cttggctcat ctgattcaga tttacaagcg aactaaggaa gatttagcct
    79261 tttcaaaagg aattttcctc caacgtgaaa gtaaatctca accttttatt attggggttt
    79321 ctgggagtgt tgccgttgga aaatccacaa caagtcgcct acttcaaatc ctactgtccc
    79381 gtacgtttac agatgctacg gttgagttgg ttacaactga tggttttctc tatcccaatc
    79441 aaaccttgat tgagcagggg attttaaatc gtaaaggatt tcctgaaagc tatgatatgg
    79501 aagctcttct caacttcttg gaccgcatca aaaatggaca agatgtagat attcctgtct
    79561 attctcatga agtttacgac atcgtacccg aagagaaaca aagtgtcaaa gctgctgatt
    79621 ttgtaattgt tgagggaatc aatgtctttc aaaatccaca aaacgatcgt ctctatatca
    79681 ctgacttctt tgacttttcc atctatgtag atgctggagt ggatgatatt gaaagttggt
    79741 atctggaccg tttcttgaaa atgctgagtc tagcccaaaa cgaccctgat agctactatt
    79801 atcgttttac tcagatgccg attggggaag tggaagcctt tgcccatcag gtctggacca
    79861 gtatcaatct cacaaatcta caaaattata ttgaaccaac cagaaatcgt gcagaagtga
    79921 ttcttcataa aagcaagaac catgaaatcg atgaaattta cttaaaaaaa taattttccc
    79981 ttgtcaaaac gtaagttttc atatataatg gtatagttag taaatatgga ggtaagaaca
    80041 ttggcaaaca ttaaatcagc tatcaaacgc gctgaattga acgttaaaca aaacgaaaag
    80101 aactcagctc aaaaatcagc tatgcgtact gctataaaag ctttcgaagc aaacccatct
    80161 gaagaacttt tccgtgctgc tagctcagct atcgataaag cagaaactaa aggtttgatt
    80221 cacaaaaaca aagcaagccg cgataaagct cgtctttcag ctaaacttgc taaataagaa
    80281 acagtccata gaggctgttt ttttgtctcc aaataggaaa aggtagaaaa tgaaaatcac
    80341 aattatcgga tattctggtt ctggtaagtc aactctagca gaaaagttat ctaactacta
    80401 ctccattcca aaactgcaca tggacacact ccaatttcaa cctggttggc aagacagtga
    80461 ctgcgaatgg atgttaaccg agataaaaaa ctttctcacc aagcataaag cttgggtcat
    80521 cgatggtaat tattcttggt gctactacca agaacgaatg caagaagctg accaaatcat
    80581 ctttctcaat ttttcgccat taacctgtct ctttagagcc tttaagcgtt atcttaaata
    80641 ccgtggaaaa gtcagagaaa gtatggcggc agattgccct gaacgctttg agtgggagtt
    80701 tatcagatgg attctttggg atgggcgtag caaaactcaa aaagaaaatt accaaaaact
    80761 ttgccaagaa tattcacata aagtcactat tcttcgaaat cagagaaagc tagatcaatt
    80821 tctggataag aaaaggaagt cctacaattc ataaagggct tcctttttgg ctataattat
    80881 tctgcaatca aggtttccaa accaaccttc atcatatcag tgaaggtatt ttgacgttct
    80941 tctgcagttg tgtcttcgtc tggattgacc aagctatcag agatggtcat gatagctagc
    81001 gcatcaacat ggtattgggc agcaagatag taaagagctg ctgcttccat ttccacagcc
    81061 ttgactcccc atttaccaag ctcgatattc ttttcaaagt aatttgagta aaagacatca
    81121 gatgacaaaa cgttcccaac gtgagtagtc ataccaagtt ctttggcgat atggtaggct
    81181 ttatcaagca aatcaaagct agcaatttgt ggaaaatcgt actgtggcca gtcattacga
    81241 acgatgtttg agttggttgc agccgcctgc gccaaaacta attcacgaac atgaacctct
    81301 tcattcaaag aacctgcagt tcccacacga atcaatttct tcacaccgta ttctacgatt
    81361 aactcacgcg cataaatcga aatagatggc attcccatcc cagttcccat gacagataca
    81421 cggtgaccct tgtaagtacc agtgtaacca aacatgttac gcacttcgtt aaaacaaaca
    81481 gcatcaccaa ggaaattctc cgcaataaac ttagcacgaa gaggatcccc aggaagaaga
    81541 attttatcag caatttcacc ctgctgagca gcaatatgga tagacataat ttatgataca
    81601 aagagcgaga agaaaacgac tgaaaattag gaacctgacg agaaatcctg atttttcagt
    81661 cagattatct attttccgag ttttccgctc gtgttcaaat caaaacacac gctctacctt
    81721 tctttatttt atattttata ttgagaaaga taccaaaccc atcaaaaagc gaagggaaaa
    81781 taggagttgg gcgcagtgag cgatgctcgc tagaccaact atctttttcc cactgctttt
    81841 agggtggggt caattccttt ctttcttaat tttgatttag aggagagtcg cccgtattca
    81901 gttcagcgaa tacagtttac ccatcctttc gtttttattt ttagaaaagt tttctactcg
    81961 tgttcaaatt agaacacgcg ctctaccttt ctgtttatac tcttcgaaaa tctcttcaaa
    82021 ccacgtcaac gtcgccttgg attatatatg tgactgactt cgtcagtctt atctacaacc
    82081 tcaaagcagt gctttgagca acctgcggct agtttcctag tttgctcttt gattttcatt
    82141 gagtattaat tttgttcttt cacagagagc tacctgagtc ctattcaagc tcaggtagta
    82201 ctttcttata aactagacaa actaactatc attgtaccat cagattacaa gacatcatcg
    82261 tcactcacct tggaattcaa tgtcgtaccc caatgggtaa ttttacggtg gggttgagct
    82321 aaaattggtc tgttttcata gattgtttgc catctattcc atagtaggcc cgtctttttc
    82381 tcaatcttaa ctcgcagatt tctcatattt tctttgattg ggaggttgag gacaaaacct
    82441 gcagtctggt tgcgaccgtt tccttcccaa gaatgactac gaacaacttg gtttccatct
    82501 ttatctactg taacttcttc ccaagttatg gagtagcggg caatgtaagc tccactgtgt
    82561 tgaattgtca atgttttatc cttcacagga gtctgactga ttggttgaac tgacttagaa
    82621 acttgtatcg ccgtttcacc attcgtagct ataaagcgga aaacttcaac ttctgcaaga
    82681 ctgagggcat tatagccttc tagctcaatc cgaacatagc gcgctttttt atggttaatc
    82741 gtaatttgtg ctgacacatc tttaggagat gttatacgtt ttcactcaat ttctttacca
    82801 gaactgtcta aaagaatgac atcaaagttt gccaatctat cctgggcagt gtctgttcgg
    82861 ttgtaaatat tgatttggcg aatggtttct tctttagcca aatctacttg ccaccaaggc
    82921 ttagattgga agtttgtatg agtgacagaa ttgtgaccat agttaccatc gactttgcca
    82981 tccacagctc ttctagcatc tcctccgaaa gctgtcgaac tttgagtaac ctgttttcct
    83041 aaggcaatat tttccattgg ttcagcgctt ggttgactag aagatcgagg cagagcctgt
    83101 ttcttaaaga atcgcacttt atccaatttc ggatcacgat aaccatgttt atccaaggta
    83161 gcttgtttac caatattaaa gttaggaata tcattcattg gactttcaaa atagccacga
    83221 gaacggtgtt taaagcgtga attacctgta aatgtaacaa tatcacgatc attatgaatc
    83281 aagggagtca caacattgtc attatcaacc acataatgct taatttttcc actaacagct
    83341 aatttacgac tttccaaacc aacatcccag aaaccattct tagcattcca aacagttctg
    83401 gaagtaatca ctttaggagc actgaaagtt gtcactttcc tcaatacatg gttataaaaa
    83461 tcaggatatt tttggtaagc ttcaacctct gcaatctgag ctaggtagca tccaagagaa
    83521 tgacctgtca tatacaactt agtaatactt atatccttgg ctaattcccc aacaaccttg
    83581 cggatatcat ccgcttgagc tggctctgtt atctctactt ttgactcttc ccttttgttt
    83641 tcaagaactt cacttgcttc cggaagcgtt tgaggagcta gtcttggctc ctctctaaga
    83701 ggagtttcta gttttggagc atcattttct gactctttca attcctcctt agaatctagc
    83761 acacctatta ccacttcaga tgttacatct tgctttactt cattggctga aattccagct
    83821 ggagctagaa atcaaagccg actacaacag atacaactcc gatacttaat tttttatgcc
    83881 aaagcgcata attcgttgac caattttcat tatttcttat ctttcttttc gtttatttac
    83941 aagcagactc aagcgaaatc tcattgtgct atatatgata agactgagaa attcagaaag
    84001 tcaattcatt ctcatctctc cttatcatac tagtctgctt ggctaggaag ctaatgctag
    84061 tatcctagaa tcttgtcttt cacaatgctg gctatcagat cagacatacc tattcttccg
    84121 cttctttcag ttataagagc aggaagaagc tcatagtatt cctctgtttc ttctttaata
    84181 cggataggca gtcaatcctg aaaagacaga ggcactcccc cttttaaatc ttttttctta
    84241 caattcagca agaatcgctt taagcaagcc tttgaaatca cctttaacac gttcagtcac
    84301 ttctacaact tcttcgtgat tgagttcttc ttggaaacca gccgcaaagt tagtgataca
    84361 tgaaattccc agaactttca agccagagtg ggctgccacg ataacttcag gaaccgtaga
    84421 cataccaact gcatctgctc ccagtgtctt ataggaacga atttctgctg gtgtttcata
    84481 agtcggacca gtaactccga tatagacacc ttcatcaagc ttgatattaa gttttttagc
    84541 cacttcatgg gcagtggcac ggtattctgg tgtgtaggcc ctagacatat ctgggaaacg
    84601 tgggccaaag tcatccaagt tttcacccat caatggattt tgccccgtca tgttgatatg
    84661 gtctgagata gccatcaagg taccaggacc aaatccgata ccgccagctg cattggttac
    84721 aataacacct tcacatccaa gaactttcat cacacgaact gggaaagtca ccacttctag
    84781 aggattccct tcatagaaat ggaaacgccc ttgaagagcc aagaccttgc gacctgccag
    84841 ttcaccatat accaatttac cagcatgacc gactactgtt gaacggcccc agtttggaat
    84901 ctcagcatag tctactacaa ctggattttc gatttcttct gccaattctc caagtcctga
    84961 tccaaggatt agaccgaact caggggctgc aattcccttt tctttcagga aagtagcagt
    85021 ttcatggatt ttgtttaaaa atgtcattgt gtgtctcctt tattattttt ttagcatttg
    85081 accaattttg tcaaaggttt tagcattacg aatagtaatg tggcggtaga aaggcacctt
    85141 cagcaagtac ttatgatagg cagtcttaga ataggattct tcagaaaatt tcccccagaa
    85201 aatcccaagt tttccaaaat aaagcacttc atctttcagc tctaaacttt caactgtcgc
    85261 gatgacttgg tccacatcca aaccctcagt gtaaaagaga aaatcttttc gtgccaagtc
    85321 tctgctccac caagctggta gattttcaag ttccgcctca aagtcctcta gactcagtaa
    85381 agaaaagctc tgaataaatg gataatggac tgcaaagaaa gtctctagct tttcaaccaa
    85441 ttgggctttg gaatctatcg aagtaaagaa aatattgcca ctattgatgt agctctcaac
    85501 cttttccagt cccaagtttg tcaattcttg acgaagctcc gccatgacga ccttattctt
    85561 accaccaaca ttgatacctc tcaccagcaa agcatagcgc gtcatcttat accaatttat
    85621 ctaagaaact ttccccaatc atagcagttt ccacaccaaa gttatcggca acagtcgctg
    85681 aaatatctgc aaaatgtcct actggaatga gaccatttcc tttaaaggca gggctatagg
    85741 ccaacaatgg aatatattcc cgagtgtgat ccgttcctgc atacgttggg tcatttccat
    85801 ggtccgcagt aatcaagaga aggtcattct ctctcatagc tgcgataatt tcaggtaagc
    85861 gttcatcaaa ctcatgcaag caatcacggt aaccgtgagc attacgacga tggccgtaaa
    85921 gggcatcaaa gtcaactagg tttgtgaatg agaatccttt ttcaaactca gcaagtccca
    85981 tagtcttcaa tagtgtatca attccatgac tatttgactt gttgtgaccc atgtcatggt
    86041 tgataccagc accgttaaag atatcgttga ttttacccac agcataagta tcgataccag
    86101 cctcattcaa tttatccaaa acagttgggg aaaatggaga tacagccaag tcacgacggt
    86161 ttgccgtacg agtgaagtta cctggttcac ctacataagg gcgagcaatg atgcgaccaa
    86221 gaagggcagg acgctcaagg gtaatcgaac gagcgtattc acagatacgg tacaattcat
    86281 ccaaaggaat aatgtcttcg tgggcagcaa tctgcaaaac agggtcagct gaagtataga
    86341 taatcaactc tccagtttcc atctgacgtg gtccaaaatc atcgataaca gccgttcctg
    86401 aataaggttt gttggcttca cgaataacct tgcgtcctga gaattcttcg atttttgtca
    86461 ggatttcttc tgggaatccg ttccagaaag tatcgaaagg ctcagtaatg ttgagtccca
    86521 tgatttccca gtgtccagtc atagtatcct taccaagaga tacttcctct aattttgttg
    86581 catatccagt tggattgctt tcagctgcta cagtcttaag aggagtttca cgaggaatat
    86641 ttccaagacc tattttagcc atgtttggga cattcaaacc aactgttttt gaaatgtgtc
    86701 ccagtgtgtc agaagctcca tctggaaccc ctgcattgac aaagttatta gcatctggtg
    86761 ctgcaccgat tcctacagaa tccagtacca ccaaatgaat acgattaaat ttagacatct
    86821 tatgccccct tctattttcc tttttttgaa gttgaaatct gaactccatc tcgtccagca
    86881 acgattacct tatccaccat ttggttgaat aaaccatgct ccacaacacc aacgacatgg
    86941 tccaattctt gtccaaaagc aattggattt tcaatgacat ccaaggcgag gtcaatgata
    87001 aaattctgca tatccgtcac aaaacgttgg ccgtcttttt cacggaaact tggtttgtag
    87061 ccagctcgtt caaaatgacg aaagacctgc tctgcaccat actgaaccac ttctactggc
    87121 aatttaaaag cacctagttt ttcgaccagc ttgctttcat ccaccaccca aatgtattct
    87181 tttgatggtg ttgcgaccac cttttccatg agaagggcac caccaccgcc tttgattcca
    87241 ttaaactgac tatccacttc atccgcgcca tcaaccgtca catcgacaaa atctacttgg
    87301 tcaatagact tgagcgggat attaaggcct tctgcctgtt tagtggtcac actagaagtt
    87361 gttacagctg taatctgcaa tccttcttcc ttgatacgac gaccgatttc ttcgacaaaa
    87421 taataggcag tcgagcctgt tccaagtcca acgaccattc catcgctcac gaactcagca
    87481 gccttgatac ctgccatttt cttcagattt tccaccgatt tacctccatc attctcagtt
    87541 cttattttac tatgaaaccg ctttttattc aagtaaaaac atcaaatcta catttttcat
    87601 caatctttct ttaaaaatat gcattttatt tttaccaaac gaataaaaat gagtttatct
    87661 tttatgtatt tgatttgttc atctctttcc agttacaaaa acaaactctt aactttgata
    87721 cgtctagttt agccttaaag caggcgcatt tcaagaatca taaattaaga gaaggaagta
    87781 gatttatctg tctattttaa acaagtttat ctttgcttac cctctcttgt tgacaaataa
    87841 ttttcattat tttgggaaga tacctgctga tttccgtcgg taagaccaca taattttctt
    87901 gagatagttc ttgggctatg gctgaatgaa gatgggtcgc tactgccaca cgctcgtaga
    87961 gactggcctg tcggaattgg cctacaaatc ctgcgatcat cccagccaga gtatctccca
    88021 ttcccccagt cgcctgataa ggaccaccaa cctgtaactg gtaataatca gattggccaa
    88081 cttcccaaat acgagtagct gggcctttct ccaccaaaat tgttccttga gggaaggaag
    88141 tcagaacact agccgttgca tcttcctttt gcttttcaat cgtaattcca gataattttt
    88201 cccattcttt ttggtgagga gttaggataa gctggcttga gggaaatgac aaacttgtcc
    88261 tagcaagaat ggtcaaggca cctccgtcta caatcaaaat ctgattttgg cttaaattaa
    88321 caaagacctg ttttactaga ttttctccag aagcatcgtc tcgtaaacca ggccccagca
    88381 agacaacttc tgccttctcc aattgctctt ttaacaattg ctggtcttga agagaaaagg
    88441 ccataggctc aggtaaatgg ctgtgcagag ccgggatatt ttccctgtcc gttccaacgg
    88501 tcaccaatcc tgcaccgctt tttacagctg ctaaagcagc catgatgatg gcacctccat
    88561 aaggataagt accaccaagc agcagcagac gaccataatc tcctttatga cttgaacgag
    88621 aacgttcaat aataactttt tctaataagg tttgattaat cactttcatc cttttttcct
    88681 ctcactttta ttatacaata aaaaggagac gcagacctcc ttttgtaatc ttatatctaa
    88741 aatttaatat tcatttctgc cattttagat atagctatag aaaatacact ctattaatcg
    88801 aatgtttctc ttattttcta tccaatgtcc gaagtgctgc ttgataagtt tgctccatca
    88861 gcatggtaat ggtcatagga ccgacacctc cagggactgg cgtgatatgg ctagcaagtg
    88921 gtgcaactgc ctcataatca acatctccac agagcttccc attttcatct cggttcatcc
    88981 caacgtcaat gacaaccgca cctggtttga caaagtcagc agtcacaaac ttggcgcggc
    89041 cgattgcgac tacaagaata tctgctttag cagccacctt ggcaagatta tgagttcgtg
    89101 agtgggtcaa ggttactgtc gcatttttag ccaaaagaag ctgagccata ggttttccaa
    89161 cgatatttga acgaccgatt acgaccgcat ttttaccttc caagtcaatc ccatattcat
    89221 gaaacatttc cataattcct gcaggtgtcg agggaatcat gactggatgt ccagaccaaa
    89281 gacgtcccat gtttagggga tggaaaccat ccacatcctt ttctgggtca atggctaata
    89341 aaaccgcctc ttcatcgata tgttttggta atggcaactg gaccaaaatc ccatgccaag
    89401 ctggatcctg attatattta gcaatcaggt ctaacaattc ctcttgagta atggtctctg
    89461 gaactcgcac tacttcgcta cgggaaccag ccgcaagagc tgacctctcc ttgttgcgaa
    89521 cgtagacttg gctggctgga ttatccccaa ccaaaatcac taccaaacca ggcactagac
    89581 ctgtttcttc ctttaatttt gcagtctttt cagccaactg cccctgcaat ttggccgcta
    89641 aagctttccc atcaataatc tgtgtcatat cacttctctt ttctttcaaa tatcttccat
    89701 tataccaaaa actgctagtg ccctctaaca cttctttcct aggttatcct atagtttcaa
    89761 actataagaa aaagctctgg ttgaactttt cactaatctt gtcttgaaat tttaaaatag
    89821 attataaaac ctttctcaag aaatctttag tccgttgttc ttgggtttgt tcaaaaatct
    89881 gctcaggtgt cccatcttca acaaccacac cgtctgccat aaagataaca cgatctgcca
    89941 cctcacgggc aaatcccatc tcatgtgtta cgataaccat agtcatccct gacttggcaa
    90001 ggtcttgcat aacagccaat acctcaccta ccatttcagg atccaaggct gaagttggtt
    90061 cgtcaaagag caaaacatct ggttccatag ccaacccacg cgcgatggca atccgttgtt
    90121 gctgcccacc cgacagactc tgtggataag cgtctgcctt atctggcaaa ccaacttttt
    90181 ccaaaagctc ttgggctctc ttctcagcaa cttccctgct ttcatctttg gtcttgatag
    90241 gtgacaaggt aatattttca atcacagtca tattaggaaa gaggttaaat tgttggaaaa
    90301 ccatgcccat cttctcacgc atggcaaaca agtcattctt cttgtccgta atatcgactc
    90361 cctcaaagat aaccttcccc ttggttgctt cctccaacaa attcatagag cgaagcaagg
    90421 tagatttccc actccctgaa ggaccgatga taacgacaac ttctcctctt ttaatctcga
    90481 ggttgattcc cttcaatact tcattctttc caaaagattt atgtaaattt tcaattttta
    90541 tcaaggtttc tgtcattatt tcttatctcc ttgtcccata tgtttttcaa aagctttcaa
    90601 ggctactgtc agaatagagg tcataatcaa gtagtaaaat gctgcaaata aaagtggtgt
    90661 taaaggtaga taggttgttg tagaaactgt tgtagcccca ttccacaact ccatgacccc
    90721 aatagctgat aagagggagc tgtccttgat aatggtgata aattcgttcc ccaatgctgg
    90781 caagatattt ttgattgctt gtggcaaaat cacataacgc atcgcatttt taggacgaat
    90841 ccctagcgaa taagccgcct ctagctgacc ttttggaacc gcattgattc cggcacgaac
    90901 agtctccgaa acataagcac cactattcat agagataatc aaaatccctg gaatcagacg
    90961 cgaaaaatca acacctaaaa ttccaatctg aatagtcgga gcattgatat gcataagagc
    91021 aaaggcaatc ataatttgaa ccatcatcgg tgtcccacgg aaaatccaaa cgtacaagtt
    91081 ggccaaccaa acaagcggtt taaactttga acgttgccca aaagccaaga caacacccaa
    91141 aatagttccc aaaaagataa cacagataga aataagaatc gtcacaacag ccccatagtt
    91201 aaaataaggt aaatacttag gtaaaaaaga aaaattcata gtcacactgc tttctaaaat
    91261 agaatactgt atgattataa catgttttga attaaaattt aaatttttta tccaatttat
    91321 ttaaaaatct ttaaactagc agaattagcg agaaatctta gttttttcta gtcaagttgg
    91381 cctcctttat ggtaaaatag taacgataag aaatgaagga gaatcaaaat ggaatcacat
    91441 ttggttagaa tcatcaaccg ccttgaagca atggcaaacg atggcggaaa tttaaaacgt
    91501 aattttgaac gcgaaggagt tgttgttgca gaagttgcgt acagccacga cgaagaaaac
    91561 ggcccaatct ttactcttcg tgacgtagaa gatcgcgaaa cgtatacgtt tgatagcatt
    91621 gacttaatcg caatggaaat ttacgaactt ctctactaat ctaaaacaag ctgggattgt
    91681 ccctgcatgt ctaagtaaaa tcctttttgt ctcacaaata ggattttttt atagtccaaa
    91741 ttcacaaaaa ttttcattgt aacaacttct caaagcttca atctttttac ttgctttaca
    91801 ccccaatcct gttataatga gagtatagaa tttgactatt tttgaccttt aaacaagtca
    91861 ggctaaagaa agaaatgagg tagatgtatg ctttgtcaaa actgtaaaat taacgactca
    91921 acaattcatc tttacaccaa tctcaatgga aaacaaaaac aaattgacct ctgtcaaaac
    91981 tgctataaga ttatcaaaac agatcctaac aatggtctct tcaaaggtat gacggatctg
    92041 aacaatcgtg acttcgatcc ctttggtgat ttcttcaatg atctaaacaa tttcagacct
    92101 tctagcaata ctcctcctat tcccccaacc caatcaggtg gaggttacgg tggaaacggc
    92161 ggttatggtt cccaaaatcg tggatctgct caaactccgc cacctagcca agaaaaaggc
    92221 ctgctggaag aatttggtat taatgtaact gaaattgccc gtcgtggaga cattgacccc
    92281 gttattgggc gcgacgatga gattatccgt gtcatcgaga ttctcaatcg tagaaccaag
    92341 aataatcctg tccttatcgg tgaacctggt gtcggaaaaa cggccgttgt cgaaggtcta
    92401 gctcagaaaa ttgtcgatgg cgatgtgcca cataaactcc aaggtaaaca agtcatccgt
    92461 ctggatgtgg ttagcttagt tcaaggaacg gggattagag gacaatttga agaacgcatg
    92521 caaaaactca tggaagaaat tcgcaaacgt gaagacatca tcctctttat cgatgaaatc
    92581 catgaaattg ttggtgctgg ttctgcgagt gatggtaata tggacgcagg aaatatcctc
    92641 aagccagccc ttgctcgtgg agaactgcaa ctagtcggtg ctactaccct caatgaatac
    92701 cgtatcattg aaaaggatgc tgccctcgag cgtcgtatgc agcctgttaa agtcgatgaa
    92761 ccaacggtgg atgaaacaat cactattctc aaagggattc aaaagaaata cgaagattac
    92821 caccacgttc aatataccga tgctgcgatt gaagcagctg caactctttc caatcgctac
    92881 atccaagatc gcttcttgcc tgacaaggcc attgacctcc tagatgaagc tggttctaag
    92941 atgaacttga ccttgaattt tgtggatcct aaagtaattg atcagcgctt gattgaggct
    93001 gaaaatctca agtctcaagc tacacgagaa gaagattttg agaaggcggc ctacttccgc
    93061 gaccagattg ccaagtataa ggaaatgcaa aagaaaaaga tcacagacca ggatactcct
    93121 atcatcagcg agaaaactat tgagcacatt atcgagcaga aaaccaatat ccctgttggt
    93181 gatttgaaag agaaagaaca atctcaactc atccatctag ctgaagatct caagtctcat
    93241 gttattggcc aagatgatgc agtcgataag attgccaagg ctattcgccg taatcgtgtc
    93301 ggacttggta cccctaaccg cccaatcgga agcttcctct tcgttgggcc aactggtgtc
    93361 ggtaagacag aactttccaa acaactggct atcgaacttt ttggttctgc tgatagtatg
    93421 attcgctttg atatgagtga atacatggaa aaacatagtg tggctaagtt ggtcggcgct
    93481 cctccaggtt atgttggcta tgatgaggct ggtcaattaa ctgaaaaagt tcgccacaat
    93541 ccatattctc tcatccttct cgatgaagtg gaaaaagctc acccagatgt tatgcacatg
    93601 tttcttcaag tcttggacga tggtcgtttg acagacgggc aaggacgcac cgttagcttc
    93661 aaggatgcca tcattatcat gacctcaaat gcaggtacag gaaagaccga agctagcgtt
    93721 ggatttggtg ctgctagaga aggacgtacc aattctgtcc tcggtgaact cggtaacttc
    93781 tttagcccag agtttatgaa ccgttttgat ggcattatcg aatttaaggc tctcagcaag
    93841 gataacctcc ttcagattgt cgagctcatg ctagcagatg ttaacaagcg cctctctagc
    93901 aacaacattc gtttggatgt aactgataag gtcaaggaaa agttggttga cctaggttat
    93961 gatccaaaaa tgggagcacg cccacttcgt cggactattc aagactatat tgaggacaca
    94021 atcactgact actaccttga aaatccaagc gaaaaagatc tcaaagcagt tatgactagc
    94081 aagggaaaca ttcagattaa atctgccaaa aaaactgaag ttaaaagttc tgaaaaagaa
    94141 aaataaatcc tatagaaaag gagtagaaaa tgaaattttt ctgcttcttt ttttactaaa
    94201 ataactgtaa tttcgtgaca gcttgccctt tgtccattat gatatatagt agactgaatc
    94261 tgaaatagta cgaaacaatt gctaaaacat ttatagaaat taattttact ttccaaatcg
    94321 atttgttctc atcttatttc aatctgctac agtcaattga aacaagagca ggataaaaaa
    94381 gcctcgtaaa aggtattgca acttggtaat accttttgga ggtgcttttt gatatgagcc
    94441 catgttttct caataggatt gtactcaggt gagtagggag gaagaggtaa aagtttatgc
    94501 ccaaactctt cgcataaaag ttctagcttc cccattctat ggaatcttgc attatccata
    94561 ataataaccg atggtgtggt taatgttggt aagaaaaact tctgaaacca agcttcaaaa
    94621 aagtcgctcg tcatcgtctc ttcgtaagtc attggaacga ttaactcacc atttgttaga
    94681 cctgtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact ttttctgggt
//
LOCUS       DAVDFK010000005        71444 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.05, whole genome shotgun sequence.
ACCESSION   DAVDFK010000005 DAVDFK010000000
VERSION     DAVDFK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.05"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..144
                     /locus_tag="VUR04_000391"
     CDS             <1..144
                     /locus_tag="VUR04_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5340346.1"
                     /translation="LYTGEVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKV
                     AIS"
     gene            163..1500
                     /locus_tag="VUR04_000392"
     CDS             163..1500
                     /locus_tag="VUR04_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET5340347.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            1579..2463
                     /locus_tag="VUR04_000393"
     CDS             1579..2463
                     /locus_tag="VUR04_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5340348.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            2463..3296
                     /locus_tag="VUR04_000394"
     CDS             2463..3296
                     /locus_tag="VUR04_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5340349.1"
                     /translation="MKKKSGIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            3314..5407
                     /gene="nanB"
                     /locus_tag="VUR04_000395"
     CDS             3314..5407
                     /gene="nanB"
                     /locus_tag="VUR04_000395"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET5340350.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLFISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVNTFFPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            5419..6522
                     /locus_tag="VUR04_000396"
     CDS             5419..6522
                     /locus_tag="VUR04_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET5340351.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            6696..7394
                     /locus_tag="VUR04_000397"
     CDS             6696..7394
                     /locus_tag="VUR04_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET5340352.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPHEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            7413..8930
                     /locus_tag="VUR04_000398"
     CDS             7413..8930
                     /locus_tag="VUR04_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET5340353.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9055..10383
                     /locus_tag="VUR04_000399"
     CDS             9055..10383
                     /locus_tag="VUR04_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340354.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            10636..11502
                     /locus_tag="VUR04_000400"
     CDS             10636..11502
                     /locus_tag="VUR04_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5340355.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            11518..12357
                     /locus_tag="VUR04_000401"
     CDS             11518..12357
                     /locus_tag="VUR04_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5340356.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            12630..13082
                     /locus_tag="VUR04_000402"
     CDS             12630..13082
                     /locus_tag="VUR04_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5340357.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            13224..13532
                     /locus_tag="VUR04_000403"
     CDS             13224..13532
                     /locus_tag="VUR04_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340358.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGTYAAKYGISMARSI
                     LNRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDAHDKIPNNGRINF
                     "
     gene            13816..14460
                     /locus_tag="VUR04_000404"
     CDS             13816..14460
                     /locus_tag="VUR04_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET5340359.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            14629..15546
                     /locus_tag="VUR04_000405"
     CDS             14629..15546
                     /locus_tag="VUR04_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET5340360.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            15564..16448
                     /locus_tag="VUR04_000406"
     CDS             15564..16448
                     /locus_tag="VUR04_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5340361.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(16464..17315)
                     /locus_tag="VUR04_000407"
     CDS             complement(16464..17315)
                     /locus_tag="VUR04_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET5340362.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            17515..19572
                     /gene="pbp2b"
                     /locus_tag="VUR04_000408"
     CDS             17515..19572
                     /gene="pbp2b"
                     /locus_tag="VUR04_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET5340363.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            19583..20179
                     /gene="recR"
                     /locus_tag="VUR04_000409"
     CDS             19583..20179
                     /gene="recR"
                     /locus_tag="VUR04_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET5340364.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            20355..21398
                     /locus_tag="VUR04_000410"
     CDS             20355..21398
                     /locus_tag="VUR04_000410"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET5340365.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            21482..22855
                     /locus_tag="VUR04_000411"
     CDS             21482..22855
                     /locus_tag="VUR04_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET5340366.1"
                     /translation="MKLTIHEIAQVVGVKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALYLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            22842..23453
                     /locus_tag="VUR04_000412"
     CDS             22842..23453
                     /locus_tag="VUR04_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5340367.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            23544..24248
                     /locus_tag="VUR04_000413"
     CDS             23544..24248
                     /locus_tag="VUR04_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET5340368.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFMVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            24467..25840
                     /gene="ftsA"
                     /locus_tag="VUR04_000414"
     CDS             24467..25840
                     /gene="ftsA"
                     /locus_tag="VUR04_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET5340369.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDVGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            25857..27116
                     /gene="ftsZ"
                     /locus_tag="VUR04_000415"
     CDS             25857..27116
                     /gene="ftsZ"
                     /locus_tag="VUR04_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET5340370.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27121..27792
                     /locus_tag="VUR04_000416"
     CDS             27121..27792
                     /locus_tag="VUR04_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET5340371.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            27802..28341
                     /locus_tag="VUR04_000417"
     CDS             27802..28341
                     /locus_tag="VUR04_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET5340372.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            28341..28604
                     /locus_tag="VUR04_000418"
     CDS             28341..28604
                     /locus_tag="VUR04_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET5340373.1"
                     /translation="MIFLIRMIYNAVDIYSLILIAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            28601..29386
                     /locus_tag="VUR04_000419"
     CDS             28601..29386
                     /locus_tag="VUR04_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET5340374.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            29395..30183
                     /gene="divIVA"
                     /locus_tag="VUR04_000420"
     CDS             29395..30183
                     /gene="divIVA"
                     /locus_tag="VUR04_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET5340375.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            30531..33323
                     /locus_tag="VUR04_000421"
     CDS             30531..33323
                     /locus_tag="VUR04_000421"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET5340376.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKYGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            33770..34110
                     /locus_tag="VUR04_000422"
                     /pseudo
     CDS             33770..34110
                     /locus_tag="VUR04_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508814.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34645..35337
                     /locus_tag="VUR04_000423"
     CDS             34645..35337
                     /locus_tag="VUR04_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET5340377.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            35390..37801
                     /locus_tag="VUR04_000424"
     CDS             35390..37801
                     /locus_tag="VUR04_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET5340378.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDCQRQLNISKALVMTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLWFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38051..38752
                     /locus_tag="VUR04_000425"
     CDS             38051..38752
                     /locus_tag="VUR04_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340379.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            38754..41462
                     /locus_tag="VUR04_000426"
     CDS             38754..41462
                     /locus_tag="VUR04_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5340380.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     IVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     LKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(41558..42049)
                     /gene="tpx"
                     /locus_tag="VUR04_000427"
     CDS             complement(41558..42049)
                     /gene="tpx"
                     /locus_tag="VUR04_000427"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET5340381.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42172..43101)
                     /gene="psaA"
                     /locus_tag="VUR04_000428"
     CDS             complement(42172..43101)
                     /gene="psaA"
                     /locus_tag="VUR04_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET5340382.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43133..43981)
                     /locus_tag="VUR04_000429"
     CDS             complement(43133..43981)
                     /locus_tag="VUR04_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET5340383.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(43978..44700)
                     /locus_tag="VUR04_000430"
     CDS             complement(43978..44700)
                     /locus_tag="VUR04_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET5340384.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGRAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            44991..46883
                     /gene="pepO"
                     /locus_tag="VUR04_000431"
     CDS             44991..46883
                     /gene="pepO"
                     /locus_tag="VUR04_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET5340385.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(47006..47635)
                     /locus_tag="VUR04_000432"
     CDS             complement(47006..47635)
                     /locus_tag="VUR04_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET5340386.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            48629..50851
                     /locus_tag="VUR04_000433"
     CDS             48629..50851
                     /locus_tag="VUR04_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET5340387.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            50881..51324
                     /locus_tag="VUR04_000434"
     CDS             50881..51324
                     /locus_tag="VUR04_000434"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET5340388.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(51534..51777)
                     /locus_tag="VUR04_000435"
                     /pseudo
     CDS             complement(51534..51777)
                     /locus_tag="VUR04_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(51796..52209)
                     /locus_tag="VUR04_000436"
     CDS             complement(51796..52209)
                     /locus_tag="VUR04_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340389.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGLLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(52340..52969)
                     /locus_tag="VUR04_000437"
                     /pseudo
     CDS             complement(52340..52969)
                     /locus_tag="VUR04_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(53168..53818)
                     /locus_tag="VUR04_000438"
     CDS             complement(53168..53818)
                     /locus_tag="VUR04_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET5340390.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            53930..54772
                     /locus_tag="VUR04_000439"
     CDS             53930..54772
                     /locus_tag="VUR04_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET5340391.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            54848..55285
                     /locus_tag="VUR04_000440"
     CDS             54848..55285
                     /locus_tag="VUR04_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET5340392.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            55354..55656
                     /locus_tag="VUR04_000441"
     CDS             55354..55656
                     /locus_tag="VUR04_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340393.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(55747..56820)
                     /locus_tag="VUR04_000442"
     CDS             complement(55747..56820)
                     /locus_tag="VUR04_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET5340394.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            56976..57653
                     /locus_tag="VUR04_000443"
     CDS             56976..57653
                     /locus_tag="VUR04_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340395.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            57646..58620
                     /locus_tag="VUR04_000444"
     CDS             57646..58620
                     /locus_tag="VUR04_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5340396.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(58669..60612)
                     /gene="thrS"
                     /locus_tag="VUR04_000445"
     CDS             complement(58669..60612)
                     /gene="thrS"
                     /locus_tag="VUR04_000445"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET5340397.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(60670..60846)
                     /locus_tag="VUR04_000446"
     CDS             complement(60670..60846)
                     /locus_tag="VUR04_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET5340398.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(60853..60993)
                     /locus_tag="VUR04_000447"
     CDS             complement(60853..60993)
                     /locus_tag="VUR04_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET5340399.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(61250..61624)
                     /locus_tag="VUR04_000448"
     CDS             complement(61250..61624)
                     /locus_tag="VUR04_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340400.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPLVILIISLLYSYRFRFSLWWLVGNGLLFYFTIITFGEFILIYLLIYETVALVGM
                     DSGISIKHILQKMKNKKLSQNP"
     gene            61860..62489
                     /locus_tag="VUR04_000449"
     CDS             61860..62489
                     /locus_tag="VUR04_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET5340401.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVIGGAGS
                     LYIDETKMTRLLDTPDFPEEFKPLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            62630..62899
                     /gene="rpsO"
                     /locus_tag="VUR04_000450"
     CDS             62630..62899
                     /gene="rpsO"
                     /locus_tag="VUR04_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET5340402.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            63714..64328
                     /locus_tag="VUR04_000451"
     CDS             63714..64328
                     /locus_tag="VUR04_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET5340403.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(64621..65370)
                     /locus_tag="VUR04_000452"
     CDS             complement(64621..65370)
                     /locus_tag="VUR04_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET5340404.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPINRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            65503..67839
                     /locus_tag="VUR04_000453"
     CDS             65503..67839
                     /locus_tag="VUR04_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET5340405.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DNLLLSGSFLASGSVLARVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            68368..69831
                     /locus_tag="VUR04_000454"
     CDS             68368..69831
                     /locus_tag="VUR04_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET5340406.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNILYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            69824..70252
                     /locus_tag="VUR04_000455"
     CDS             69824..70252
                     /locus_tag="VUR04_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5340407.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            70230..70679
                     /locus_tag="VUR04_000456"
     CDS             70230..70679
                     /locus_tag="VUR04_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5340408.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            70707..71018
                     /locus_tag="VUR04_000457"
     CDS             70707..71018
                     /locus_tag="VUR04_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET5340409.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            71044..>71444
                     /locus_tag="VUR04_000458"
     CDS             71044..>71444
                     /locus_tag="VUR04_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340410.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWNALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPT"
BASE COUNT        21413 a        12918 c        15884 g        21229 t
ORIGIN      
        1 ttatacacag gggaagtaga acagttagtt catttgagag ctggcgaatg cctcatcact
       61 tttccagaag atttacatca acccaaggtt cgtataaatg atgaacctgt gaaaaaagtt
      121 gtctttaaag ttgcgatttc ttaatgtaga aagagaagaa cgatgaaaaa aatgagaaag
      181 tttttatgtc tagctggaat tgcgctagcg gctgttgcct tggtagcttg ttcaggaaaa
      241 aaagaagcta caactagtac tgaaccacca acagaattat ctggtgagat tacaatgtgg
      301 cactccttta ctcaaggacc ccgtttagaa agtattcaaa aatcagcaga tgctttcatg
      361 caaaagcatc caaaaacgaa aatcaagatt gaaacatttt cttggaatga cttctatact
      421 aaatggacta caggtttagc aaatggaaat gtgccagata tcagtacagc tcttcctaac
      481 caagtaatgg aaatggtcaa ctcagatgct ttggttccgc taaatgattc tatcaagcgt
      541 attggacaag ataaatttaa cgaaactgcc ttaaatgaag caaaaatcgg agatgattac
      601 tactctgttc ctctttattc acatgcacaa gtcatgtggg ttagaacaga tttgttaaaa
      661 gaacataata ttgaggttcc taaaacttgg gatcaactct atgaagcttc taaaaaattg
      721 aaagaagctg gagtttatgg cttgtctgtt ccgtttggaa caaatgactt aatggcaaca
      781 cgtttcttga acttctacgt acgtagtggt ggaggaagcc tcttaacaaa agatcttaaa
      841 gcagacttga caagccaact tgctcaagat ggtattaaat actgggttaa attgtataaa
      901 gaaatctcac ctcaagattc tttgaacttt aatgtccttc aacaagctac cttgttctat
      961 caaggaaaaa cagcatttga ctttaactct ggcttccata tcggaggaat taatgccaac
     1021 agtcctcaat tgattgattc gattgatgct tatcctattc caaaaatcaa agagtctgat
     1081 aaagaccaag gaattgaaac ctcaaacatt ccaatggttg tttggaaaaa ttcaaaacat
     1141 ccagaagttg ctaaagcatt cttagaagca ctttataatg aagaagacta cgttaaattc
     1201 cttgattcaa ctccagtagg tatgttgcca actattaagg ggattagcga ttctgcagcc
     1261 tataaagaaa atgaaactcg taagaaattt aaacatgctg aagaagtaat tactgaagct
     1321 gttaaaaaag gtactgctat tggttatgaa aatggaccaa gtgtacaagc tggtatgtta
     1381 actaaccaac acattattga acaaatgttc caagatatca ttacaaatgg aacagatcct
     1441 atgaaagcag caaaagaagc agaaaaacaa ttaaacgatt tatttgaggc tgttcagtag
     1501 atgtaaaaga ctagaaaata ggtgggctag tgagctgaaa agctctagcc caatcttgta
     1561 aaagaaggga gaaggagaat ggttaaagaa cgtaatttaa ctcgctggat atttgttttg
     1621 ccagctatga ttatcgtagg attactcttt gtttatccgt ttttctcgag tattttttat
     1681 agctttacca ataagcattt gattatgcct aattataaat ttgttggttt ggctaactat
     1741 aaagctgtgc tatcagatcc caacttcttt aatgcgttct ttaattcaat taagtggacc
     1801 gttttctcat tagttggtca agttttagta gggtttgtat tggctttagc tcttcacaga
     1861 gtacgccact tcaagaaatt atataggacc ttattgattg ttccttgggc atttcctacc
     1921 atcgttattg ccttctcttg gcagtggatt ctaaacgggg tttatggcta cttacctaat
     1981 ctaatcgtaa aattaggttt aatggaacat acacctgcat ttttgacaga tagtacatgg
     2041 gcattcctat gtttggtgtt tatcaacatt tggtttggag caccaatgat tatggttaat
     2101 gtgctttcag ctttgcaaac agtaccagaa gaacaatttg aggctgctaa gatagatggt
     2161 gcttcaagtt ggcaggtgtt caagtttatc gtctttccac atattaaagt ggttgtagga
     2221 cttctagttg ttttgagaac tgtatggatc tttaataact ttgacattat ctacctcatt
     2281 actggtggtg gaccagccaa tgctacaacg acgcttccaa tttttgctta caacctgggc
     2341 tggggaacta aattgttggg tcgtgcttca gcagttacag tattgctctt tatcttcttg
     2401 gtggcgattt gctttatcta ctttgctatc atcagtaagt gggaaaagga gggtagaaaa
     2461 taatgaagaa gaaatccggt atttatttag atattctctc acatgtactt ttagttggtg
     2521 cgaccatcgt tgcagttttc ccattggtat ggattatcat atcttctgtc aaagggaaag
     2581 gggaattaac tcagtatcca acacgatttt ggcctgaaca gtttacatta gattatttca
     2641 ctcatgttat caacgatttg cacttcattg ataacattcg aaacagttta atcattgcct
     2701 tggctacaac ccttattgcg attattattt ctgctatggc agcctatggt attgttcgat
     2761 tctttcctaa attgggagca atcatgtcga gactactcgt cattacctac attttcccac
     2821 caattttgtt agcaattccc tattcaattg ccattgctaa agttgggtta acaaatagtt
     2881 tatttggctt gatgatggtt tatctatctt ttagtgttcc atatgcagtt tggctcttag
     2941 ttggattttt ccaaacagtt ccaattggaa ttgaagaagc ggctagaatt gatggtgcaa
     3001 ataaatttgt tacgttttat aaagttgtgc taccgattgt agcaccaggt attgtagcaa
     3061 cagctattta tacatttatc aatgcttgga atgaattcct gtatgccttg attttgatta
     3121 acaatacagg aaagatgaca gtagcagtag cccttcgttc acttaatggt tcagaaatac
     3181 tagactgggg agatatgatg gcagcgtctg ttattgtagt tcttccatca attattttct
     3241 tctctatcat ccaaaataag attgcaagtg gattatcaga aggatctgtg aagtagacga
     3301 aagaaggaaa aaaatgaata aaagaggtct ttattcaaaa ctaggaattt ctgttgtagg
     3361 cattagtctt ttaatgggag tccccacttt gattcatgcg aatgaattaa actatggtca
     3421 actgttcata tctcctattt ttcaaggagg ttcatatcaa ctgaacaata agagtataga
     3481 tatcagccct ttgttattag ataaattgtc tggagagagt cagacagtag taatgaaatt
     3541 taaagcagat aaaccaaact ctcttcaagc tttgtttggc ctatctaata gtaaagcagg
     3601 ctttaaaaat aattactttt caattttcat gagagattct ggtgagatag gtgtagaaat
     3661 aagagacgcc caaaagggaa taaattattt attttctaga ccagcttcat tatggggaaa
     3721 gcataaagga caggcagttg aaaatacact agtatttgta tctgattcta aagataaaac
     3781 atacacaatg tatgttaatg gaatagaagt gttctctgaa acagttaata cattttttcc
     3841 aatttcaaat ataaatggta tagataaggc aacactagga gctgttaatc gtgaaggcaa
     3901 ggaacattac ctcgcaaaag gaagtattga tgaaatcagt ctatttaaca aagcaattag
     3961 tgatcaggaa gtttcaaata ttcccttgtc aaatccattt cagttaattt tccaatcagg
     4021 agattctact caagctaact attttagaat accgacacta tatacattaa gtagtggaag
     4081 agttctatca agtattgatg cacgttatgg tgggactcat gattctaaaa gtaagattaa
     4141 tattgccact tcttatagtg atgataatgg gaaaacgtgg agtgagccaa tttttgctat
     4201 gaagtttaat gactatgagg agcagttagt ttactggcca cgagataata aattaaagaa
     4261 tagtcaaatt agtggaagtg cttcattcat agattcatcc attgttgaag ataaaaaatc
     4321 tgggaaaacg atattactag ctgatgttat gcctgcgggt attggaaata ataatgcaaa
     4381 caaagccgac tcaggtttta aagaaataaa tggtcattat tatttaaaac taaagaagaa
     4441 tggagataac gatttccgtt atacagttag agaaaatggt gtcgtttatg atgaaacaac
     4501 taataaacct acaaattata ctataaatga taagtatgaa gttttggagg gaggaaagtc
     4561 tttaacagtc gaacaatatt cggttgattt tgatagtggc tctttaagag aaaaacataa
     4621 tggaaaacag gtccctatga atgttttcta caaagattcg ttatttaaag tgactcctac
     4681 taattatata gcgatgacaa ctagtcagaa tagaggagag agttgggaac aatttaagtt
     4741 gttgcctccg ttcttaggag aaaaacataa tggaacttac ttatgtcccg gacaaggttt
     4801 agcattaaaa tcaagtaaca gattgatttt tgcaacatat actagtggag aactaaccta
     4861 tctcatttcg gatgatagtg gtcaaacatg gaagaaatcc tcagcttcaa ttccgtttaa
     4921 aaatgcaaca gcagaagcac aaatggttga actgagagat ggtgtgatta gaacattctt
     4981 tagaaccact acaggtaaga tagcttatat gactagtaga gattctggag aaacatggtc
     5041 gaaagtttcg tatattgatg gaattcaaca aacttcatat ggcacacaag tatctgcaat
     5101 taaatactct caattaattg atggaaaaga agcagtcatt ttgagtacac caaattctag
     5161 aagtggccgt aagggaggcc aattagttgt cggtttggtc aataaagaag atgatagtat
     5221 tgattggaga taccactatg atattgattt gccttcgtat ggttatgcct attctgcgat
     5281 tacagaattg ccaaatcatc acataggtgt actgtttgaa aaatatgatt cgtggtcgag
     5341 aaatgaattg catttaagca atgtagttca gtatatagat ttggaaatta atgatttaac
     5401 aaaataaagg agaaaaacat ggttaaatac ggtgttgttg gagcagggta ttttggagct
     5461 gaattggctc gctatatgca aaagaatgat ggagcagaga ttactcttct ctatgatcca
     5521 gataatgcag aggcgattgc agaagaattg ggagcaaaag tagcaagttc cttagatgag
     5581 ttggtttcta gcgatgaagt agactgtgtt atcgtcgcaa ctccaaataa tcttcataag
     5641 gaaccggtta ttaaggctgc acagcatggt aaaaatgttt tctgtgaaaa accaattgcg
     5701 ctttcttatc aagattgtcg cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt
     5761 atggcaggac atattatgaa tttctttaat ggtgttcatc atgcaaaaga actcattaat
     5821 caaggagtta tcggagacgt tctatattgt catacagctc gtaatggttg ggaagaacaa
     5881 caaccgtcag tatcatggaa aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac
     5941 atccatgaat tggattgcgt tcaattcctt atggggggca tgcctgaaac tgtaaccatg
     6001 acaggtggaa atgtggccca tgaaggtgaa catttcggtg atgaagatga tatgattttt
     6061 gtcaatatgg aattttctaa taagcgtttt gccttgttag aatggggttc agcttatcgt
     6121 tggggtgaac attatgtctt aatccaagga agcaaaggtg ccatccgctt agacttattc
     6181 aactgtaaag gaactcttaa gctagatggg caagaaagct atttcttgat tcacgaatcg
     6241 caagaagaag atgatgatcg gactcgtatc tatcatagta cagagatgga tggagcaatt
     6301 gcttatggta aaccaggtaa acgtactcca ttatggctat catctgtcat tgataaagaa
     6361 atgcgctatc tgcatgagat tatggaagga gctccagtat cagaagaatt tgcaaaactt
     6421 ttgacaggtg aagctgccct agaagcaatt gctactgcag atgcttgtac ccagtctatg
     6481 tttgaagatc gcaaagtaaa attgtcagaa attgtaaaat aaattttggt attctcctat
     6541 ttataggtcg acttgctcct ctgaaagtac ttttagagga gctgtttgac tttgctagtt
     6601 tttgaaactg aaatctatta tactacaaac tattgaaagc gttttaattt taaggtataa
     6661 taatctcata gaaataaaga aaaggaggaa agaggatgcc acagattagc aaagaagcct
     6721 tgattgagca aatcaaagat ggaatcatcg tttcttgtca ggctcttcct catgaaccgc
     6781 tttatacaga agcgggaggg gtgattccct tgctggtcaa agcggctgag caaggtggag
     6841 cagtcggtat ccgagcaaac agtgttcgcg atatcaagga aattaaggag gtcactaaac
     6901 ttccaatcat tgggattatc aaacgtgatt atccacctca tgaacccttc atcacggcta
     6961 ctatgaaaga agttgatgaa ttggcagaac tggacatcga ggtgattgct ctggattgta
     7021 ccaagcgtga acgctacgat ggtttggaaa ttcaagagtt cattcgtcag gttaaggaga
     7081 aatatcctaa tcagcttttg atggctgata ctagtatctt cgaagaaggg ctagcagctg
     7141 tagaagcagg aattgacttt gtcggaacaa ccttatcagg ctacacatcc tatagtccaa
     7201 aagtagacgg tccagatttt gaattgatta agaaactctg tgatgccggt gtagatgtca
     7261 ttgcagaagg aaaaattcat acaccagaac aagccaaaca aatccttgaa tatggagtgc
     7321 gaggcatcgt tgttggtggc gctattacta gaccaaaaga gattacagaa cgcttcgttg
     7381 ctagtcttaa ataagatgtg agggggagtt ttatgtttaa agttttacaa aaagttggaa
     7441 aagcttttat gttacctata gctatacttc ctgcagcagg tctacttttg gggattggtg
     7501 gtgcactttc aaacccaacc acgatagcaa cttatccaat actagacaat agtatttttc
     7561 aatcaatatt ccaagtaatg agctctgcag gagaggttgt attcagtaat ttgtcactac
     7621 ttctctgtgt gggattatgt attggcttag cgaaacgaga taaaggaacc gctgcgttag
     7681 caggagtaac tggttactta gttatgactg caacgatcaa agctttggta aaacttttta
     7741 tggcagaagg atctgcaatt gatactggag ttattggagc attagttgtc ggaatagttg
     7801 ccgtatattt gcacaaccga tataacaata ttcaattacc ttccgcttta ggattctttg
     7861 gaggttcacg cttcgttcct attgttacat cgttctcttc tatcttgatt ggctttgtct
     7921 tctttgttat ttggccacct ttccaacaac ttcttgtttc tacaggtgga tatatttctc
     7981 aggcgggtcc aattggaact tttctatatg gatttttaat gagactttct ggagcagtag
     8041 gcttacatca tataatttac cctatgtttt ggtatactga acttggtggt gttgaaactg
     8101 ttgcaggaca aacagtggtt ggagctcaaa aaatattttt tgctcaatta gccgatccgg
     8161 cccattctgg attatttaca gaaggaacaa ggttttttgc aggtcgtttc tcaacaatga
     8221 tgttcggttt accggctgcc tgtttagcga tgtaccatag tgttcctaaa aatcgtcgta
     8281 aaaaatacgc gggtttgttt tttggagttg ctttaacatc ttttattacc ggtattacag
     8341 aaccaattga atttatgttt ctattcgtca gtccggttct atatgttgtt cacgcattcc
     8401 ttgatggtgt tagcttcttt attgcagacg tcttaaatat ttcaatagga aacacatttt
     8461 caggaggtgt aatcgatttc actttatttg gaattttgca ggggaatgct aagacgaatt
     8521 gggttcttca gattccaatt ggacttattt ggagtgtttt gtattatatt atttttagat
     8581 ggttcattac tcaattcaac gttctaacgc caggacgagg agaagaagta gattctaaag
     8641 aaatttctga atccgcagat tcaacttcaa atactgcaga ttatttaaaa caggatagcc
     8701 tacaaattat cagagcgttg ggtggatcaa ataatataga agatgtagat gcttgtgtga
     8761 cacgtttacg tgtagctgta aaagaagtta atcaagttga taaagcactt ttaaaacaaa
     8821 ttggtgcagt tgatgtctta gaagtgaagg gtggcattca agcaatctat ggagcaaaag
     8881 caatcttata taaaaatagt attaatgaaa ttttaggtgt agatgattaa gtacttactg
     8941 acttaataaa aaacagagga gagtgatgga tgagtaggat gaaatgaaat cgcatacaag
     9001 aaataaagaa ctcattatcc aagttggata cgcttattac ataggagaat acaaatgaaa
     9061 tttagaaaat tagcttgtac agtacttgcg ggtgctgcgg ttcttggtct tgctgcttgt
     9121 ggcaattctg gcggaagtaa agatgctgcc aaatcaggtg gtgacggtgc caaaacagaa
     9181 atcacttggt gggcattccc agtatttacc caagaaaaaa ctggtgacgg tgttggaact
     9241 tatgaaaaat caatcatcga agcgtttgaa aaagcaaacc cagatataaa agtgaaattg
     9301 gaaaccatcg acttcaagtc aggtcctgaa aaaatcacaa cagccatcga agcaggaaca
     9361 gctccagacg tactctttga tgcaccagga cgtatcatcc aatacggtaa aaacggtaaa
     9421 ttggctgagt tgaacgacct cttcacagat gaatttgtta aagatgtcaa caatgaaaac
     9481 atcgtacaag caagtaaagc tggagacaag gcttatatgt atccgattag ttctgcccca
     9541 ttctacatgg caatgaacaa gaaaatgtta gaagatgctg gagtagcaaa ccttgtaaaa
     9601 gaaggttgga caactgatga ttttgaaaaa gtattgaaag cacttaaaga caagggttac
     9661 acaccaggtt cattgttcag ttctggtcaa gggggagacc aaggaacacg tgcctttatc
     9721 tctaaccttt atagcggttc tgtaacagat gaaaaagtta gcaaatatac aactgatgat
     9781 cctaaattcg tcaaaggtct tgaaaaagca actagctgga ttaaagacaa tttgatcaat
     9841 aatggttcac aatttgacgg tggggcagat atccaaaact ttgccaacgg tcaaacatct
     9901 tacacaatcc tttgggcacc agctcaaaat ggtatccaag ctaaactttt agaagcaagt
     9961 aaggtagaag tggtagaagt accattccca tcagacgaag gtaagccagc tcttgaatat
    10021 cttgtaaacg ggtttgcagt attcaacaat aaagacgaca agaaagtcgc tgcatctaag
    10081 aaattcatcc agtttatcgc agatgacaag gagtggggac ctaaagacgt agttcgtaca
    10141 ggtgctttcc cagtccgtac ttcatttgga aaactttatg aagacaaacg catggaaaca
    10201 atcagtggct ggactcaata ctactcacca tactacaaca ctattgatgg atttgctgaa
    10261 atgagaacac tttggttccc aatgttgcaa tctgtatcaa atggtgacga aaaaccagcg
    10321 gatgctttga aagccttcac tgaaaaagca aacgaaacaa tcaaaaaagc tatgaaacaa
    10381 tagtccttag ttattctatg aaaaagtaat tttttaaaga acctaagagt gtataccccc
    10441 ttttccctct acacagatag tgtaagaaaa gggggctttt gtttaaaatg taagaaactg
    10501 tcacgaaatt aaaatgaagt tcttacataa gcgaaccata aaaaatttca ttttgatttt
    10561 aaaacagttc aagaaagtca aaaaattatt ctatttgaaa gagaggtgcc gactgtgaaa
    10621 gtcaataaaa tccgtatgcg ggaaacagtg atttcctacg ctttcctagc accagtatta
    10681 ttcttctttg tcatatttgt gttggctccg atggtgatgg gcttcattac aagtttcttt
    10741 aactactcaa tgactaaatt tgagtttgta ggcttggata actatatccg tatgtttaaa
    10801 gatcctgtct ttacaaaatc tctgattaac acagttattt tggttattgg atctgtacca
    10861 gttgttgttc tattctcact ctttgtagca tctcagacct atcatcaaaa tgtcattgcc
    10921 agatccttct accgtttcgt cttcttcctt cctgttgtaa cgggtagtgt tgccgtgaca
    10981 gttgtttgga aatggattta tgacccacta tcagggattc taaactttgt ccttaagtcc
    11041 agccacatca tcagccaaaa catttcttgg ttgggagata aaaactgggc attgatggcg
    11101 attatgatta ttctcttgac cacttcagtt ggtcagccca tcatccttta tatcgctgcc
    11161 atggggaata ttgacaattc actggttgaa gcggcgcgtg ttgatggtgc aactgagttt
    11221 caagtttttt ggaagattaa atggccaagc cttcttccaa caactcttta tattgcaatc
    11281 atcacaacaa ttaactcatt ccagtgtttc gccttgattc agcttttgac atctggtggt
    11341 ccaaactact caacaagtac cttgatgtac tacctttacg aaaaagcctt ccaattgaca
    11401 gaatacggct atgccaacac aattggtgtc ttcttggcag tcatgattgc tatcgtaagc
    11461 tttgttcaat ttaaagtact tggaaacgac gtagaatact aaagaaagga gacagctatg
    11521 caatctacag aaaaaaaacc attaacagcc tttactgtta tttcaacaat cattttgctc
    11581 ttgttgactg tgctgttcat ctttccattc tactggattt tgacaggggc attcaaatca
    11641 caacctgata caattgttat tcctcctcag tggttcccta aaatgccaac catggaaaac
    11701 ttccaacaac tcatggtgca gaaccctgcc ttgcaatgga tgtggaactc agtatttatc
    11761 tcattggtaa ccatgttctt agtttgtgca acctcatctc tagcaggtta tgtattggct
    11821 aaaaaacgtt tctatggtca acgcattcta tttgctatct ttatcgctgc tatggcgctt
    11881 ccaaaacaag ttgtccttgt accattggta cgtatcgtca acttcatggg aatccacgat
    11941 actctctggg cagttatctt gcctttgatt ggatggccat tcggtgtctt cctcatgaaa
    12001 cagttcagtg aaaatatccc tacagagttg cttgaatcag ctaaaatcga cggttgtggt
    12061 gagattcgta ccttctggag tgtagccttc ccgattgtga aaccagggtt tgcagccctt
    12121 gcaatcttta ccttcatcaa tacttggaat gactacttca tgcagttggt aatgttgact
    12181 tcacgtaaca atttgaccat ctcacttggg gttgcgacca tgcaggctga aatggcaacc
    12241 aactatggtt tgattatggc aggagctgcc cttgctgctg ttccaatcgt cacagtcttc
    12301 ctagtcttcc aaaaatcctt cacacagggt attactatgg gagcggtcaa aggataatac
    12361 tctgcgaaaa tcgaatgcaa actacgtcag cttcaccttg ccatacttaa gtattgcctg
    12421 tggttagctt cctagtttgt tcttcaattt tcattgagta taggaaaatc aatctatcaa
    12481 aatacagaag tatattttat agatttagag aatatagaag ttataagtgt ctacaaaatg
    12541 gagggtatgc agttacttta tgaagttttg tcagacactt atcaacttaa gaatggtttt
    12601 agttaactat cagaaacgaa ggaaagagta tgatttttga cgatttgaaa aacatcacct
    12661 tttacaaagg gattcatccc aatttagaca aggctatcga ctatctctac caacatcgta
    12721 aagattcatt cgaattagga aagtatgaga ttgatggaga taaagtcttt ctagttgttc
    12781 aggaaaatgt cctcaatcaa gttgagaata atcaatttga acaccataag aactatgcag
    12841 atttgcattt gctggtagaa ggacatgaat attcgagcta cggttcacgt atcaaagacg
    12901 aggcagtagc attcgacgaa gcgagtgaca ttggctttgt tcattgtcat gaacactacc
    12961 cactcttgtt gggttatcac aattttgcga ttttcttccc aggtgagcca catcagccaa
    13021 atggttatgc aggcatggaa gaaaaggttc gaaaatatct ctttaaaatt ttgattgatt
    13081 aaaaatagga tgaattgttt ttttgtaaag ctttgacaat actctaccat gaaattgatc
    13141 tttgtgaggt agggaaatga gaataaaata tttaaaaatt ggtatcttct tgtcagtctg
    13201 tgtatgctac aagagctagt ttcttggatg gacagggaat tacagttgat gagatggctt
    13261 ggataattag gggcattgtg aatgcattga ttggtagata cataaaatta ggtacttatg
    13321 cggctaagta tggtattagt atggcgcgtt ctatcttaaa tagggcagct gcaactgcgg
    13381 cagcaagagt aggattattg actaagattt ttggatggat tttacgaata gctgtgctcg
    13441 cagctgatgt atatggtaat tttgccaaca atattgctgt agcttgggat gcacatgata
    13501 aaatccctaa caatggtcgt ataaactttt aaaatgcgag aatgaaagca ctttgtattt
    13561 ttttattgaa tatgttagct tggacagtgc ttgcaatgat aatccgtgga gggctagatg
    13621 gatttgatag gcatacttgg agtactattt taattgcttc gctgttcggg gtatatgatt
    13681 ataagcccat agataaaaat agaaaaaagt ccaaaagaaa aaagaaaaaa tagatttgtt
    13741 catggtaggg acttatgaaa gctttactga caaaaaagaa aacagtttac aaagaaaaat
    13801 gatggaggag caaacatggc acaaaaagga gtaagcctta tcaaggcagc atttgataca
    13861 gacaactttc tcatgcgttt tagtgagaaa gtcttggaca tcgtgacagc caatcttctt
    13921 tttgtcgtct cttgtttgcc catcgtgacg attggagtgg ctaaaatcag cctctacgag
    13981 accatgttcg aagttaagaa gagcagacgg gtgcctgttt ttaaaatcta tctaagatct
    14041 ttcaagcaaa atctgaaact aggtcttcag ctgggtttaa tggagttagg aattgtgttt
    14101 cttacccttt cagatctcta tcttttctgg ggtcaaacag ctctgccctt ccaattgctg
    14161 aaagccattt gtttaggtat tctgattttt cttactatcg tgatgctggc tagttaccct
    14221 atcgcggcac gttatgacct atcttggaaa gaaattcttc aaaaaggatt gatgttggct
    14281 agttttaact ttccttggtt cttcctcatg ttagccattc ttgtcctcat tgtgatggtt
    14341 ctttatctgt ccgccttcag tctactctta ggtggctcag tcttcttact ttttgggttt
    14401 ggactattgg tctttatcca gactggattg atggagaaaa ttttcgcaaa ataccaatag
    14461 gagccttatt tctgaaacta ctttcaaacg ctccaaacgc tattctataa gcgagaaact
    14521 aaaatctaag tgtctataag atattgaaag ccttttcggt aaagtgtata ctaaagaagt
    14581 aaagaaaaat ctgctttagc agaaaataaa aataatagga gaaaatctat gtcagatttg
    14641 aaaaaatacg aaggtgtcat tccagccttc tacgcatgtt atgatgatca aggagaagta
    14701 agcccagaac gtacgcgtgc cttggttcaa tacttcattg ataaaggtgt tcaaggtctt
    14761 tatgtcaatg gttcttctgg tgaatgtatc taccaaagcg ttgaagatcg caagttgatt
    14821 ttggaagaag tcatggcggt agccaaaggt aaattgacca tcattgctca tgttgcctgc
    14881 aacaatacta aagatagtat ggaacttgct cgccatgctg aaagcttggg agtagatgct
    14941 attgcaacga ttccaccaat ttatttccgc ttgccagaat actcagttgc caaatactgg
    15001 aacgatatca gttctgcagc tccaaacaca gactacgtga tttacaacat tcctcaattg
    15061 gcaggggttg ctttgactcc aagtctttac acagaaatgt tgaaaaatcc tcgtgttatc
    15121 ggtgttaaga actcttctat gccagttcaa gatatccaaa cctttgtcag ccttggtggg
    15181 gaagaccata tcgtctttaa tggtcctgat gagcagttcc taggaggacg cctcatgggt
    15241 gctagggctg gtatcggtgg tacttatggt gctatgccag aactcttctt gaaactcaat
    15301 cagttgattg cggataagga cctagaaaca gcgcgtgaat tgcagtatgc tatcaacgca
    15361 atcattggta aactcacttc tgctcatgga aatatgtacg gtgtcattaa agaagtcttg
    15421 aaaatcaatg aaggcttgaa tattggatct gttcgttcac cattgacacc agtgactgaa
    15481 gaagatcgtc cagttgtaga agcggctgct gccttgattc gtgaaaccaa ggagcgcttc
    15541 ctctaatcta aaaggaggta tttatgacat actacgttgc aattgatatc ggtggaacca
    15601 acatcaagta tggtttggtt gatcaagagg ggcaacttct tgaatcgcat gaaatgccaa
    15661 ctgaggcgca taagggtgga cctcatatct tacaaaagac caaagatatc gtagctagtt
    15721 atttagaaaa aggcccagta gcaggtgttg ccatatcttc tgctgggatg gtggatccgg
    15781 ataagggtga gattttctat gctgggcctc aaatccctaa ctacgcaggc acccagttca
    15841 aaaaggaaat cgaagaaagc tttactattc cttgtgagat tgaaaatgat gtcaactgtg
    15901 caggtcttgc tgaggcagta tctggttcag gcaagggagc aagtgtgaca ctttgcttga
    15961 ccattggaac cggtatcggt ggttgcttga ttatggatag gaaagtcttc catggtttta
    16021 gcaattcagc ctgtgaagtc gggtatatgc atatgcagga tggagctttt caggatctcg
    16081 cttctacaac agctttagtg aaatatgtag ctgaagccca tggagaagat gttgatcagt
    16141 ggaatggccg acgtatcttt aaggaagcta ctgaaggaaa caaaatctgc atggaaggta
    16201 ttgaccgtat ggttgactat ctaggaaaag gtctggcaaa tatttgttat gtggccaatc
    16261 cagaagtggt tattcttggt ggtggtatca tggggcaaga ggctatcctc aaacctaaga
    16321 tccgcacagc cttgaaagag gcattggtac caagtttagc agaaaaaaca cgattagaat
    16381 ttgcccatca ccaaaataca gcagggatgt tgggtgcata ttatcatttt aagacaaaac
    16441 aatcctagtt tggctcagcc aaactaggat tttcttacac gtttttgtct acgatagccg
    16501 ttgagttttt tattttccca gtagctatta aagatttttt ccttgctttc gcgattgatt
    16561 tccaaaaagt aggcataaat caaatcgata aagaagagca taggaagttg agcggatatt
    16621 cgttggatgt aggagggttg gctgtgggtg gctacaagaa cagtctctgt ataggtctgg
    16681 ctatctttat tgggaacact tgtaaagagt acagtctttg cccccatctc cttggcatct
    16741 aatagactat ctaaaataga aggagttgag cctgaaagtg agaagcccag tactagacaa
    16801 ttttcatcca tgatgctggt tgtccaggca aagccgtctt ggtctgtcaa agcttcgcag
    16861 accacaccta gtcgcataaa acgtaatttc atttcacggg cgacgaggcc agaactccct
    16921 gttccaaaga agtagatacg ctcagcatct tcgattagct gggcaattcg ctctagttgg
    16981 atttcgtcaa tcaagtcttg tgtttgttcc ctcatattgc tataacttct gaggactcgt
    17041 ttggtcagtg gactgtgctt ggagacttgg ttggcttgat tttctgcctg atgttgatat
    17101 tggaaaataa attctcggta gccagtaaag ccacactttt tagcaaagcg ggtcaaagca
    17161 gcttgagaaa tatgtaattt ttgggtgact tgttgagaag ataaatcatc tgtaatcgtt
    17221 tcagcttgca aaaaatagcg agcgatttct tgctctaggt ctgtcatttc ttcaaaatgt
    17281 gaatcaatga tagttgcgat atctggtttg tccataggga aagctccttt acatgagtca
    17341 tactggaaga ctagattagg gaatagtcac acttcattat aacacataat ataaggatag
    17401 ataaataaaa acgcatctct gttttaaaaa cgaaaaaatc gaaaaagctt ctctcttttc
    17461 cataattttc tactcaaatt gtggtacaat taagagtaag attttaagtt agaaatgaga
    17521 ctgatttgta tgagaaaatt taacagccat tcgattccga ttcggcttaa tttattgttt
    17581 tcaatcgtca ttttactctt tatgaccatt attggtcgtt tgttgtatat gcaggttttg
    17641 aacaaggatt tttacgaaaa aaagctagcc tcagctagtc agaccaagat tacaagcagt
    17701 tcagcccgtg gggaaattta tgatgctagt ggaaaacctt tggtagaaaa tacgttaaag
    17761 caggttgttt cctttacgcg tagcaataaa atgacggcta cagacttaaa agaaacagct
    17821 aaaaagttac tgacttatgt gagcatcagt tctccaaatt tgacagaacg ccagctggcg
    17881 gattactatt tggctgatcc tgaaatctat aaaaaaatag tggaagctct cccaagtgag
    17941 aaacgcttgg attcagatgg caatcgtcta tccgaatcag aactgtataa caatgcggtc
    18001 gatagtgtac aaacgagtca actaaattat acagaggatg aaaagaaaga aatctatctt
    18061 tttagtcagt taaatgctgt tggaaacttt gcgacaggaa ccattgcgac agatcctcta
    18121 aatgattctc aggtggctgt tattgcctct atttcaaagg agatgcctgg cattagtatt
    18181 tctacttctt gggatagaaa ggttttggaa acttcccttt cttctatagt tgggagtgta
    18241 tccagtgaaa aagctggtct cccagcggaa gaagcagaag cctatcttaa aaaaggctat
    18301 tctctaaatg atcgtgtagg aacctcctat ttggaaaagc aatatgaaga gaccttacaa
    18361 ggaaaacgct cggtaaaaga aatccatctg gataaatatg gcaatatgga aagcgtggat
    18421 acaattgagg aaggtagtaa gggaaacaat atcaaactga ccattgattt ggccttccaa
    18481 gatagcgtgg atgctttact gaaaagttat ttcaattccg agctagaaaa tggtggagcc
    18541 aagtattctg aaggtgtcta tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct
    18601 atgtcaggga ttaaacatga cttgaaaacg ggagagttga cgcctgattc cttgggaacg
    18661 gtaaccaatg tctttgttcc aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg
    18721 gaaaatggag tcttgtcagg aaaccagacc ttgacagacc agtccattgt cttccaaggt
    18781 tcagctccca tcaattcttg gtatactcag gcttacggtt cattccctat cacagcggtc
    18841 caagctctgg agtattcatc aaatacctat atggtccaaa cagccttagg tcttatgggg
    18901 caaacctatc aacccaatat gtttgtcggc accagcaatc tagagtctgc tatggagaaa
    18961 ctgcgttcaa cctttggcga atatggcttg ggtactgcga caggaattga cctaccagat
    19021 gaatctactg gatttgttcc caaagagtat agctttgcta attacattac taatgccttt
    19081 gggcagtttg ataactatac gccgatgcag ttggctcagt atgtagcaac tattgcaaat
    19141 aatggtgttc gtgtggctcc tcgtattgtt gaaggcattt atggtaataa tgataaggga
    19201 ggactgggtg acttgattca gcaactgcaa ccgacagaga tgaataaggt caatatatcc
    19261 gactccgata tgagcatctt gcaccaaggt ttttatcagg ttgcccatgg tactagtgga
    19321 ttgacaactg gacgtgcctt ttcaaatggt gccttggtat ccattagcgg aaaaacaggt
    19381 acagccgaaa gctatgtggc agatggtcag caagcaacca ataccaatgc ggtggcctat
    19441 gccccatctg ataatcccca aatcgctgtc gcagtggtct ttcctcataa taccaatcta
    19501 acaaatggtg taggaccttc cattgcgcgt gacattatca atctgtatca aaaataccat
    19561 ccaatgaact agaaaggaaa ttatgcttta tccaacacct attgccaagt tgattgacag
    19621 ttattctaag ttaccaggta tcgggattaa gacggctacg cgtctggcct tttatacgat
    19681 tgggatgtct gctgatgatg tcaatgaatt tgcaaaaaat ctcctttctg ctaagagaga
    19741 attgacatat tgttctattt gtggacgttt gacagacgac gatccttgtt ctatctgtac
    19801 tgatccgact cgtgaccaga caacaatttt agttcttgag gatagtagag atgtggcagc
    19861 catggaaaat atccaagaat accatggact ctatcatgtc cttcatggcc tcatttctcc
    19921 tatgaatggt atcagtccgg acgatatcaa tctcaagagc cttatgactc gtcttatgga
    19981 tagtgaggtt tcagaagtga ttgtggcgac taatgctaca gcggatggtg aagcgacttc
    20041 catgtatctt tcacgtttgc tcaagccggc tggtatcaag gttacgcgtc tagcacgagg
    20101 tctcgctgtg ggagcggaca ttgagtatgc ggacgaagtg acactcttac gagccattga
    20161 aaatcggaca gagttgtaag tgtaggcaaa tttacgaact ccattcattt ataaaaaatc
    20221 aaagaggctg aaaatcgttc ctatcggcct ctttttgtat agtgtgatga gtaggatcag
    20281 gttcaagttt taaaaaacca agcaaatatg atatactaaa gagcgagtat tctagtagaa
    20341 ttaggacaaa taatatgaaa caaacgatta ttcttttata tggtggacgg agtgcggaac
    20401 gcgaagtctc tgtcctttca gctgagagtg tcatgcgtgc ggtcgattac gaccgtttca
    20461 cagtcaagac tttctttatc agtcagtcag gtgactttat caaaacacag gaatttagtc
    20521 atgctccggg gcaagaagac cgtctcatga ccaatgaaac cattgattgg gataagaaag
    20581 ttgcaccaag tgctatctac gaagaaggtg cagtggtctt tccagtcctt cacgggccaa
    20641 tgggagaaga tggctctgtt caaggattct tggaagtttt gaaaatgcct tacgttggtt
    20701 gcaacatttt gtcatcaagt cttgccatgg ataaaatcac gactaagcgt gttctggaat
    20761 ctgctggtat tgcccaagtt ccttatgtgg ctatcgttga aggcgatgat gtgactgcta
    20821 aaatcgctga agtggaagaa aaattggctt atccagtctt cactaagccg tcaaacatgg
    20881 ggtctagtgt cggtatttct aagtctgaaa accaagaaga actccgtcaa gccttagaac
    20941 ttgccttccg atatgatagc cgtgtcttgg ttgagcaagg agtgaatgcc cgtgaaattg
    21001 aggttggcct cttgggtaac tacgatgtca agagcacgct accaggagaa gttgtcaagg
    21061 acgttgcctt ttatgactac gatgccaagt atattgataa caagattact atggatattc
    21121 ctgccaaaat cagtgatgat gtggtggctg tcatgcgtca aaatgcagaa acagccttcc
    21181 gtgccattgg tggccttggt ctatctcgtt gcgatttctt ctatacagat aagggagaga
    21241 tttttctcaa cgagctcaat accatgccag gtttcaccca gtggtctatg tacccactac
    21301 tttgggacaa tatggggatc agctacccaa aactaatcga gcgtttggtt gaccttgcca
    21361 aggaaagttt tgacaagcgc gaagcgcatt tgatataaaa tgaaagagag ggtagaagcc
    21421 agaaccatca ctgcaaggtg actagagttc tcggacttca gcccttttta aaggagtaga
    21481 aatgaaatta acaatccatg aaattgccca agttgttgga gtcaaaaatg atatcagtat
    21541 ctttgaggac acccagttag aaaaagctga gtttgatagt cgtttgattg gaactggaga
    21601 tttatttgtg ccacttaaag gtgcgcgtga tggccatgat tttattgaaa cagcctttga
    21661 aaatggtgca gcagtaacct tgtctgagaa agaggtctca aatcatcctt acattctagt
    21721 agatgatgtt ttgacagcct ttcaatccct agcatcctac tatcttgaaa aaacgactgt
    21781 tgatgtcttt gctgttacag gttcaaatgg caagacaacg actaaggata tgttggcgca
    21841 tttactgtca acgacctaca agacctacaa aacacaaggc aactacaata acgagattgg
    21901 ccttccctac acagttctac acatgcctga aggaacagaa aagttggttt tggagatggg
    21961 gcaggaccac ttgggcgata ttcatctctt gtctgaattg gctcgtccaa aaacagccat
    22021 cgtgaccttg gttggagaag cccatttggc ctttttcaaa gaccgttcag agattgctaa
    22081 gggaaaaatg caaattgcag acggaatggc ttcaggttcc ttgcttttag cgccggctga
    22141 ccctatcgta gaggactatt tgccaactga taaaaaggtg gtccgttttg ggcaaggggc
    22201 agagttggaa atcacagact tggttgagcg taaggacagt ctgaccttta aggctaattt
    22261 cttggaacaa gccctttatt tgccagtaac tggcaagtac aatgcgacaa atgctatgat
    22321 tgcatcctat gttgccctac aagaaggagt ttcagaggag caaattcatc aggccttcca
    22381 aggtcttgaa ttgacgcgta atcgtactga gtggaagaaa gcagccaatg gagcagatat
    22441 cctgtcagac gtatataatg ccaatccaac tgctatgaag ctgattttag agactttctc
    22501 tgccattcca gccaatgaag gtggcaagaa aattgcagtg ttggcggata tgaaggagct
    22561 tggtgaccag tctattcaac tccataacca gatgattttg agcctttctc cagatgtgct
    22621 tgataccgtt attttctatg gagaagacat tgctgaatta gcccaattgg ccagtcaaat
    22681 gttcccaatt ggccacgttt actacttcaa gaaaacagaa gaccaagacc aatttgaaga
    22741 cctagtcaag caggtcaagg aaagcctcag tgccaatgat caaatcttgc tcaagggctc
    22801 taactctatg aacctagcca tgttggtaga aagtttagaa aatgaaacca agtgattttg
    22861 ttaagtatct gcaaagaatg attgccctta cagatactgg cttaaccttt acaaaagatc
    22921 cttttgaccg tgagcgctac gaggacttgc gaagtctgtt atctgaaatg ttgaatcagg
    22981 gatcagacct ggatgcagaa gaagtagcag aagtcttgaa accaacttca gcttatgcga
    23041 ctcccttaat ggacgtccgt gcttggattg ttgaggatga gaagatttgt ctggttaggg
    23101 gacaaggaga ggatagttgg gctttgccag gtggctttgg tgaagtcggc tattctccaa
    23161 ctgaaaatat tctcaaggaa attgaagaag aaaccggttt taaagccaaa gttgaaagac
    23221 tgctagctgt ttttgatacc aatcgtttcc aactacagag taaacaatat gcaaagtttg
    23281 tttttgaatg taagtttctc gatggacaat tccaagaaaa tcaagaaatt gcagaccttc
    23341 aattttttgc cattgatcaa ctgccagcct tatctgaaaa acgcattacc aaggagcaaa
    23401 tagagattct ttggcaggtt tatcaaggtc agagggagca atatcttgac taagaagatg
    23461 attatcgtat ttttaaatcc atttttaaca actagcatgg tataataata tgcaggaaaa
    23521 ttttgaatta tgaggaagac tagatgaatt tatgggatat tttctttacg actcaggcaa
    23581 ccgagccgcc caaatttgac cttttttggt atgttagcct atttacgctc ttagccttaa
    23641 ccttttatac agcccatcgc tatcgtgaaa agaaggttta ccaacgattt ttccaaatct
    23701 tgcagactgt tcagttaatc cttctttatg gttggtactg ggtcaatcat atgccactgt
    23761 cagaaagcct acccttttac cattgccgta tggctatgtt tgtggtactc ttgcttcctg
    23821 gtcaatccaa atataaacaa tactttgcat tattgggaac atttgggaca ttagcagcct
    23881 ttgtttatcc agtgccagat gcttaccctt ttccacatat caccattcta tcctttatct
    23941 ttggtcattt agcactcttg gggaactctc tagtttatct attgagacag tataatgcgc
    24001 gattgctgga tgtgaaggga atttttctca tgacctttgc cctaaatgcc ttgattttta
    24061 tggtcaattt ggtgacaggt ggcgattacg gatttttgac aaaaccgcca ttggttgggg
    24121 atcacggtct agtagctaat tatttacttg tttcaattgt gctggtagct actatcagtt
    24181 tgactaagaa aatcttagaa ttctttttag ctcaagaagc agaaaaaatg attgcaaagg
    24241 aagcttaaca cagagctttc ttttttgctc ttagagagtt tttacaagca gcttataaaa
    24301 taagaatttc tgaatagaca aactcaaaaa atggctggga aatttaggaa aaaagcaagc
    24361 acgattaaat tttttgtgtt ataatatttt gtgaatagct atgcctatgt ttagctatgg
    24421 aataatacga agtgcgaaac ttggaagata gagaggaagc gatgtaatgg ctagagaagg
    24481 cttttttaca ggtctagata ttggaacaag ctctgtcaag gtgcttgtgg ccgagcagag
    24541 aaatggtgaa ttaaatgtaa ttggcgtgag taatgccaaa agtaaaggtg taaaggatgg
    24601 aattattgtt gatattgatg cagcagcaac tgctatcaag tcagccattt cccaagcgga
    24661 agaaaaggca ggcatttcga ttaaatcagt gaatgtcggc ttgcctggta atcttttgca
    24721 ggtagaacca actcagggga tgattccagt aacatctgat actaaggaaa ttacggatca
    24781 agatgttgaa aatgttgtca aatcagcttt gacaaagagt atgacacctg accgtgaagt
    24841 cattaccttt attcctgaag aatttattgt ggatggtttc caagggattc gtgacccacg
    24901 tggtatgatg ggggttcgcc ttgaaatgcg tggtttgctt tatacaggac ctcgtactat
    24961 cttgcacaat ttgcgtaaga cggttgagcg tgcaggtgtt caggttgaaa atgttatcat
    25021 ttcaccacta gcaatggttc agtctgtttt gaacgaaggg gaacgtgaat ttggtgctac
    25081 agtgattgat gtgggggcag gtcaaacgac tgtcgctaca atccgtaatc aagaactcca
    25141 gttcacacat attctccaag aaggtggaga ttatgtaact aaagatatct ccaaggtttt
    25201 gaaaacctct cgcaaattag cggaaggctt gaaactgaat tacggggaag cctatccgcc
    25261 tcttgcaagc aaagaaacct tccaagtaga ggttattgga gaagtggaag cagtcgaagt
    25321 gacggaagcc tacttgtcag aaattatttc tgcacgaatc aagcacatcc ttgaacaaat
    25381 caagcaagaa ttagatagaa ggcgtctatt ggacctccct ggtggtattg tcttaatcgg
    25441 tgggaatgcc attttaccag gtatggttga gcttgctcag gaagtctttg gcgtccgtgt
    25501 caagctttat gttccaaatc aagttggtat ccgtaatcca gcctttgcgc atgtgattag
    25561 tttatcagaa tttgcgggtc aattaacaga agttaatctt ttggctcagg gagcgataaa
    25621 aggtgagaat gacttaagtc atcagccaat tagttttggt gggatgctgc aaaaaacagc
    25681 tcagtttgta caatcaacgc ctgttcaacc agctcctgct ccagaagtag agccggtggc
    25741 gcctacagaa ccaatggcgg atttccaaca agcttcacaa aataaaccga aattagcaga
    25801 tcgtttccgt ggcttgatcg gaagcatgtt tgacgaataa agaggaaaaa taaattatga
    25861 cattttcatt tgatacagct gctgctcaag gggcagtgat taaagtaatt ggtgtcggtg
    25921 gaggtggtgg caatgccatc aaccgtatgg tcgacgaagg tgttacaggc gtagaattta
    25981 tcgcagcaaa cacagatgta caagcattga gtagtacaaa agctgagact gttattcagt
    26041 tgggacctaa attgactcgt ggtttgggtg caggaggtca acctgaggtt ggtcgtaaag
    26101 ccgctgaaga aagcgaagaa acactgacgg aagctattag tggtgccgat atggtcttca
    26161 tcactgctgg tatgggagga ggctctggaa ctggagctgc tcctgttatt gctcgtatcg
    26221 ccaaagattt aggtgcgctt acagttggtg ttgtaacacg tccctttggt tttgaaggaa
    26281 gtaagcgtgg acaatttgct gtagaaggaa tcaatcaact tcgtgagcat gtagacactc
    26341 tattgattat ctcaaacaac aatttgcttg aaattgttga taagaaaaca ccgcttttgg
    26401 aggctcttag cgaagcggat aacgttcttc gtcaaggtgt tcaagggatt accgatttga
    26461 ttaccaatcc aggattgatt aaccttgact ttgccgatgt gaaaacggta atggcaaaca
    26521 aagggaatgc tcttatgggt attggtatcg gtagtggaga agaacgtgtg gtagaagcgg
    26581 cacgtaaggc aatctattca ccacttcttg aaacaactat tgacggtgct gaggatgtta
    26641 tcgtcaacgt tactggtggt cttgacttaa ccttgattga ggcagaagag gcttcacaaa
    26701 ttgtgaacca ggcagcaggt caaggagtga acatctggct cggtacttca attgatgaaa
    26761 gtatgcgtga tgaaattcgt gtaacagttg tcgcaacggg tgttcgtcaa gaccgcgtag
    26821 aaaaggttgt ggctccacaa gctagaactg ctactaacta ccgtgagaca gtgaaaccag
    26881 ctcattcaca tggctttgat cgtcattttg atatggcaga aacagttgaa ttgccaaaac
    26941 aaaatccacg tcgtttggaa ccaactcagg catctgcttt tggtgattgg gatcttcgcc
    27001 gtgaatcgat tgttcgtaca acagattcag tcgtttctcc agtcgagcgc tttgaagccc
    27061 caatttcaca agatgaagat gaattggata cacctccatt tttcaaaaat cgttaagtaa
    27121 atgaatgtaa aagaaaatac agaacttgtt tttcgagaag ttgcagaggc tagtctgagc
    27181 gctcatcgag agagtggttc ggtctctgtc attgcagtta ccaagtatgt agatgtaccg
    27241 acagcggaag ccttgcttcc gctaggtgtt catcatatcg gtgaaaatcg tgtagataag
    27301 tttctggaaa aatatgaagc tttaaaagat cgagatgtga cttggcattt gattggtacc
    27361 ttgcaaagac gtaaggtgaa agatgtcatt caatacgttg attatttcca tgcattggac
    27421 tcagtaaagc tagcagggga aattcaaaaa agaagtgacc gagtcatcaa gtgtttcctt
    27481 caagtaaata tttctaaaga agaaagcaaa cacggttttt cgagagagga actgctggaa
    27541 atcttgccag agttagccag actagataag attgaatatg ttggtttaat gacgatggca
    27601 ccttttgagg ctagcagtga gcagttgaaa gagattttca aggcggccca agatttacaa
    27661 agagaaattc aagagaaaca aattccaaat atgcctatga ccgagttaag tatgggaatg
    27721 agtcgtgatt ataaagaagc gattcaattc ggttccactt ttgttcgtat aggtacatca
    27781 ttttttaagt aggagagaac catgtcttta aaagatagat tcgatagatt tatagattat
    27841 tttacggagg atgaggattc aagtctccct tatgaaaaaa gagatgagcc tgtgtttact
    27901 tcagtaaatt cttcacagga accggctctc ccaatgaatc aaccttcaca gtcggctggt
    27961 acaaaagaga acaatatcac cagacttcat gcaagacaac aggaattggc aaatcagagt
    28021 cagcgtgcaa cggataaggt cattatagat gttcgttatc ctagaaaata tgaggatgca
    28081 acagaaattg ttgatttatt ggcaggaaac gaaagtatct tgattgattt tcagtatatg
    28141 acagaggtgc aggctcgtcg ttgtttggac tatttggatg gagcttgtca tgttttagct
    28201 ggaaatttga aaaaggtagc ttctaccatg tatttgttga caccagtgaa cgttattgta
    28261 aatgttgaag atatccgttt accagatgaa gatcaacagg gtgagttcgg ttttgatatg
    28321 aagcgaaata gagtacgata atgatttttt taattcgtat gatttataat gcagtggata
    28381 tttactccct gattttgata gccttcgctg tcatgtcttg gtttccaggt gcctacgaat
    28441 ccagtttagg tcgttggatt gtagcgttgg tgaaaccagt gcttgctccc ttgcaacgcc
    28501 tgcctttaca gatagcgggt cttgatttat ctgtttgggt tgcgattgtt ttggttcgat
    28561 ttttaggaga aaacttagtg cgttttctgg cgatgatagg atgaataaag ggatttatca
    28621 gcatttctcc atagaagatc gtccatttct tgacaaggga atggaatgga taaagaaggt
    28681 agaagatagc tatgctcctt ttttaactcc ttttatcaat cctcatcagg agaagctatt
    28741 aaagattttg gcaaaaacct atggtcttgc ttgtagcagt agtggggaat tcgtctcgag
    28801 tgagtatgtt cgagttttat tatacccaga ttatttccaa ccagagtttt cagattttga
    28861 aatatctctt caggaaattg tgtattccaa taaatttgaa catttaacgc atgctaagat
    28921 tttagggaca gtcatcaatc aattagggat tgaacggaaa ctttttggag atatcctagt
    28981 agatgaagaa cgggcgcaga ttatgattaa tcagcagttt cttcttctct ttcaagatgg
    29041 actaaagaaa attggtcgta tacctgtttc gctggaggaa cgtcctttca ccgagaaaat
    29101 agataagcta gaacagtatc gagaactgga tttatctgtg tctagttttc gattagatgt
    29161 tcttttatca aatgttttga aactatctag gaatcaagca aaccagttga ttgaaaagaa
    29221 acttgtccaa gtaaattatc atgtggtaga caaatcagat tacactgttc aagttggaga
    29281 cttgattagt gtgagaaaat ttggtcgctt gagattactt caagataagg gacaaacgaa
    29341 aaaagagaag aaaaaaataa ccgtccagtt attattaagt aagtgaggaa tagaatgcca
    29401 attacatcat tagaaataaa ggacaagact tttggaactc gattcagagg ttttgatcca
    29461 gaagaagtcg atgaattttt agatattgtg gttcgtgatt acgaagatct tgtgcgtgcg
    29521 aatcatgata aaaatttgcg tattaagagt ttagaagagc gtttgtctta ctttgatgaa
    29581 ataaaagatt cattgagcca gtctgtattg attgctcagg atacagctga gagagtgaaa
    29641 caggcggcgc atgaacgttc aaacaatatc attcatcaag cagagcaaga tgcgcaacgc
    29701 ttgttggaag aagctaaata taaggcaaac gagattcttc gtcaagcaac tgataatgct
    29761 aagaaagtcg ctgttgaaac agaagaattg aagaacaaga gccgtgtctt ccaccaacgt
    29821 ctcaaatcta caattgagag tcagttggct attgttgaat cttcagattg ggaagatatt
    29881 ctccgtccaa cagctactta tcttcaaacc agtgatgaag cctttaaaga agtggttagc
    29941 gaagtacttg gagaaccgat tccagctcca attgaagaag aaccaattga tatgacacgt
    30001 cagttctctc aagcagaaat ggaagaatta caagctcgta ttgaggtagc cgataaagaa
    30061 ttgtctgaat ttgaagctca gattaaacag gaagtggaag ctccaactcc tgtagtgagt
    30121 cctcaagttg aagaagagcc tctgctcatc cagttggccc aatgtatgaa gaaccagaag
    30181 tagctccagt gcatccgaca ggtccaacac cagctacaga aactgttgat tcagcaccgg
    30241 gatttgaagc accgcaagaa tctgttacaa ttttataaga aatattctga gaacaatatc
    30301 ttatccttat attcccagcg agcaggagat ggtgtgagtc ctgcattccc tatcgataag
    30361 attatcctct caaaaactca agtctgaatc tagtaagatt tgacgttccc cacgttacgg
    30421 gataagaggg agaaagacta aaactttttc cgaataaagg tggtaccacg attttcgtcc
    30481 tttttggaag tcgtggtttt taatttgtta ttatttataa aggagatacc atgaaactca
    30541 aagacaccct taatcttggg aaaactgaat tcccaatgcg tgcaggcctt cctaccaaag
    30601 agccagtttg gcaaaaggaa tgggaagatg caaaacttta tcaacgtcgt caagaattga
    30661 accaaggaaa acctcatttc accttgcatg atggccctcc atacgctaac ggaaatatcc
    30721 acgttggaca tgctatgaac aagatttcaa aagatattat tgttcgttct aagtctatgt
    30781 caggatttta cgcaccattt attcctggtt gggatactca tggtctgcca atcgagcaag
    30841 tattgtcaaa acaaggtgtc aaacgtaaag aaatggactt ggttgagtac ttgaaacttt
    30901 gccgtgagta cgctctttct caagtagata aacaacgtga agattttaaa cgtttgggtg
    30961 tttctggtga ctgggaaaat ccatatgtga ccttgactcc tgactatgaa gcagctcaaa
    31021 ttcgtgtatt tggtgagatg gctaataagg gttatatcta ccgtggtgcc aagccagttt
    31081 actggtcatg gtcatctgag tcagcccttg ctgaagcaga gattgaatac catgacttgg
    31141 tttcaacttc cctttactat gccaacaagg taaaatatgg caaaggagtt ctagatacag
    31201 atacttatat cgttgtctgg acaacgactc catttaccat cacagcttct cgtggtttga
    31261 cggttggtgc agatattgat tacgttttgg ttcaacctgc tggtgaagct cgtaagtttg
    31321 tcgttgctgc tgaattattg actagcttgt ctgagaaatt tggctgggct gatgttcaag
    31381 ttttggaaac ttaccgtggc caagaactca accacatcgt aacagaacac ccatgggata
    31441 cagctgtaga agagttggta attcttggtg accacgttac gactgactct ggtacaggta
    31501 ttgtccatac agcccctggt tttggtgagg acgattacaa tgttggtatt gctaataatc
    31561 ttgaagtcgc agtgactgtt gatgaacgtg gtatcatgat gaagaatgct ggtcctgaat
    31621 ttgaaggtca attctatgaa aaggtagttc caactgttat tgaaaaactt ggtaacctcc
    31681 ttcttgccca agaagaaatc tctcactcat atccatttga ctggcgtact aagaaaccaa
    31741 tcatctggcg tgcagttcca caatggtttg cctcagtttc taaattccgt caagaaatct
    31801 tggacgaaat tgaaaaagtg aaattccact cagaatgggg taaagtccgt ctttacaata
    31861 tgatccgtga ccgtggtgac tgggttatct ctcgtcaacg tgcttggggt gttccacttc
    31921 ctatcttcta cgctgaagat ggtacagcta tcatggtagc tgaaactatt gaacacgtag
    31981 ctcaactttt tgaagaacat ggttcaagca tttggtggga acgtgatgcc aaagacctct
    32041 tgccagaagg atttactcat ccaggttcac caaacggcga gttcaaaaaa gaaactgata
    32101 tcatggacgt ttggtttgac tcaggttcat catggaatgg agtggtggta aaccgtcctg
    32161 aattgactta cccagccgac ctttacctag aaggttctga ccaataccgt ggttggttta
    32221 actcatcact tatcacatct gttgccaacc atggcgtagc accttacaaa caaatcttgt
    32281 cacaaggttt tgcccttgat ggtaaaggtg agaagatgtc taaatctctt ggaaatacca
    32341 ttgctccaag cgatgttgaa aaacaattcg gtgctgaaat cttgcgtctc tgggtaacaa
    32401 gtgttgactc aagcaatgac gtgcgtatct ctatggatat tttgagccaa gtttctgaaa
    32461 cttaccgtaa gattcgtaac actcttcgtt tcttgattgc caatacatct gactttaacc
    32521 cagctcaaga tacagtcgct tacgatgagc ttcgttcagt tgataagtac atgacgattc
    32581 gctttaacca gcttgtcaag accattcgtg atgcctatgc agactttgaa ttcttgacga
    32641 tctacaaggc cttggtgaac tttatcaacg ttgacttgtc agccttctac cttgattttg
    32701 ccaaagatgt tgtttacatt gaaggtgcca aatcactgga acgccgtcaa atgcagactg
    32761 tcttctatga cattcttgtc aaaatcacca aactcttgac accaatcctt cctcacactg
    32821 cggaagaaat ttggtcatat cttgagtttg aaacagaaga cttcgtccaa ttgtcagaat
    32881 taccagaggc tcaaactttt gctaaccaag aagaaatctt ggatacatgg gcagccttca
    32941 tggacttccg tggacaagca caaaaagcct tggaagaagc tcgtaatgca aaagttatcg
    33001 gtaaatcact tgaagcacac ttgacagttt atccaaatga agtggtgaaa actctactcg
    33061 aagcagtaaa cagcaatgta gctcaacttt tgatcgtgtc agacttgacc atcgcagaag
    33121 gaccagctcc ggaagctgcc cttagcttcg aagatgtagc cttcacagtt gaacgtgctg
    33181 ctggtgaagt atgtgaccgt tgccgtcgta tcgacccaac aacagcagaa cgcagctacc
    33241 aggcagtcat ctgtgatcat tgtgcaagca tcgtagaaga aaactttgcg gacgctgtcg
    33301 cagaaggatt tgaagagaaa taagattgaa aagtctaggc aaaattcaat ttgagaagaa
    33361 aagacaacta attttatagt ctattaaacg cattgtatca cgtttttgaa cacctgatat
    33421 gatgcgtttt ttatttattt taaaaatttg cgaggtatga ctttttatac tcaacaagaa
    33481 tcaaagagaa acttagcaag ctaacagtag taagataaaa taggaatttg atattaggga
    33541 taagattggt aaatagtgta atatttttac aacaataaat ttatatagtt atttttggtt
    33601 tctgaaaagt attatatttt atttcatatt atacaaattt ttattttata atatcagaaa
    33661 atactttttt taaaagcaaa tatgatacaa ttttatttga aaaaaataaa aaaggagatt
    33721 ttattatgaa attaaaaaca cttgctttaa ttagtggtat cgtcgtcttg tgggaggaat
    33781 tttacttctt attggtcctt ttgtcttgtt gggaacagcg gtaaacacag ctgctacaac
    33841 tcttaatgga ggagctactg caggggcttt ttcaggtgtt gccttactct tgaatgcctt
    33901 gaagattgca aatcttgttc ttggtatcat tgctattgtt tactataaag gagataagcg
    33961 tgtaggtgca gctccgtctg tactaatgat tgtttctggt ggagttagtc tcattctatt
    34021 ccgttcttag gatgggttgg ggggattctt gctattatcg gaggatctct attcctttca
    34081 acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa gaacaaaaaa
    34141 gtttatcggt ataggagtag ctctattatc tctttctctt ctagttgcat gtggaacata
    34201 aagttcaaag aatacttcaa caagtaatga tgagaagaca gtagcaacat ccaatagttc
    34261 aaaagaaaca atcactttcg atataccggt tgtaacagac gatgcgattg aatcaatacg
    34321 cacttatgca gattatatag atctttataa aaatattttt gatgattatt ttactaaagc
    34381 tgaggaaggt ttcaaaggca cagctatgga aaataatgac tcgtttacta aactaaaaga
    34441 gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta aataatgaag atagaataga
    34501 aacagccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct ttttggtttt
    34561 gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg gaaacctcgg
    34621 aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca cggtgagtct
    34681 gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc tgaaaaaggt
    34741 acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga atttgaccaa
    34801 gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct tgaagcttct
    34861 gaccaattat gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt
    34921 ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca agttcacatc
    34981 tggcgtcgtt catacgatgt attgcctcca aacatggacc gtgatgatga gcactcagct
    35041 cacacagacc gtcgttacgc ttcacttgac gactcagtta tcccagatgc tgaaaacttg
    35101 aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc agctcttaaa
    35161 gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct tgtaaaacac
    35221 atcaaaggtt tgtcagatga cgagatcatg gacgtggaaa tccctaactt cccaccattg
    35281 gtattcgaat tcgacgaaaa attgaacgtc gtttctgaat actaccttgg aaaataaaaa
    35341 attgtaagtc tagaattgat ttctaggctt tttatgttag tatggaagta tgataaggaa
    35401 taaaaaacaa gattatgtac tggcctacaa gcaaccagct tcaaccactt acatgggttg
    35461 ggaagaagaa gctttaccga taggcaatgg ttctttagga gcaaaagtat ttggccttat
    35521 aggggctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc cacttcctga
    35581 tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag ctgagattcg
    35641 gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat
    35701 tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt
    35761 cagccagcaa ggtacgactt tgtctcaggt gacggactgt cagagacagc tgaatattag
    35821 taaggcactt gtgatgactt cttatgtcta taagggaacg cgatttgaac gtgaagcttt
    35881 tgcgagtttt ccagatgatc tcttggttca gcgttttact aaggaagggg cggaaactct
    35941 agattttact atagaactat ccttgacctg tgatttggct tctgatgaaa agtatgagca
    36001 ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa
    36061 gggaagagtt aaggataatg atctgtggtt tgctagttat ctagcttggg aaacggatgg
    36121 agatattaga gtttggtcag atagggttca gatatcagga gccagttatg ccaatctctt
    36181 cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga
    36241 tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct atacccaatt
    36301 gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga
    36361 agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg
    36421 gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag
    36481 agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc
    36541 tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta
    36601 tgttaccaat ctcctagagg cggtctttcc ggtcatcaac tatgtagatg atttgcgtgt
    36661 ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcagaaag gtgaggaaaa
    36721 tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta
    36781 ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt atgaagccta
    36841 ttcattttat agggaccaag actatctcag ggagaaaatt tatcccatgt tgagggaaac
    36901 ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtgtcttc
    36961 tccgtcttat tccccagaac atgggccgat ttcgattggc aatacttatg accaatctct
    37021 gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac tggatgagga
    37081 cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc
    37141 tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga
    37201 ggcccagcat cggcacgctt cccatctagt gggactctat cctggcaatc tctttagcta
    37261 caagggacaa gagtatattg aagcggcacg tgctagcctc aatgatcgtg gagatggcgg
    37321 cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggcaatcg
    37381 agcccataaa ttattggcag agcagttaaa aacatccacc ttgccaaatc tttggtgtag
    37441 ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt
    37501 actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg cttggtcaac
    37561 aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga
    37621 taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta
    37681 tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat
    37741 ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta
    37801 agaagatgtt ataaggcagt aatttgaaac ttccttttaa taaggattta agaatatagg
    37861 cagtttccaa ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa
    37921 tcaaagagca caaactagga agctagccgc aggttgctca aaacagtgtt ttgaggttgt
    37981 agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag
    38041 ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc aggttgggga
    38101 cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat
    38161 tatccttggt gcttcaggtg caggcaagtc aacagttctt aaccttcttg ggggaatgga
    38221 taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca
    38281 ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt
    38341 ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga cagatgcctt
    38401 gaatcctgat caggtcttga cagatgtagg tctggctcat cgtctcaata actttccagc
    38461 ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc
    38521 taaaattctt ctttgtgatg aaccgactgg agccttggat tatcagacgg gcaagcaggt
    38581 tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca tcgtgactca
    38641 taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg ccagtgtcaa
    38701 ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact agtatgatca
    38761 agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag gggcgttttt
    38821 tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc aaagtaacca
    38881 gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg
    38941 cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg
    39001 gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca
    39061 ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc
    39121 ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac agcgtgggac
    39181 aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata
    39241 ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag
    39301 gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcag tttgatcaga
    39361 aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat gccttttcat
    39421 cagcttatga agaaaaatcc aagcaacatc aggaagacct tgaacaaact ttatcagata
    39481 atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc
    39541 aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg
    39601 ctcaagctcg tatacaggct caagaaagtc aactagcttt gtttcctcaa gttcagagag
    39661 agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaggacaaac
    39721 taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa catcagcaag
    39781 tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg
    39841 gtcagggcta tcttatgtat agcaatgctt catccagtat tagagcagtg ggcaatatct
    39901 ttcctgtggt actttatgcc gtagcatcca tagtgacctt tacgaccatg actcgctttg
    39961 tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttaccgt agtaaggata
    40021 ttatcaccaa gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta
    40081 gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca aaaggcatgg
    40141 tggtgggaga aacccagatt cagttctatt ggacctatag cttactagct cttgtcttga
    40201 gttggttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgccgaag
    40261 cagcccagct tctacttctt aaacctcctg tcaaaggagc taaaatctta ttggagcgta
    40321 tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc aacatctttc
    40381 gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct
    40441 ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa
    40501 tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag
    40561 agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaaa
    40621 cgctagacaa ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt atgatgatag
    40681 agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa
    40741 aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga
    40801 ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc
    40861 actttattta tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca
    40921 acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct
    40981 tgcttatgaa tcaatctgcg gtgtctagcg ttgtccaaaa tgcttcagcc attcgactct
    41041 tcgactctgt cgctagctca ctcaatcaga ccatgaccat cttggtcatc gtatcggttc
    41101 tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag agaatccgtg
    41161 aactctccac taccaaggtt cttggttttc ataataatga agtcaccctc tacatttacc
    41221 gtgagacgat tgtgctatcc cttgtgggaa tcgtacttgg tctggtagct ggtttctatt
    41281 tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat ccgcaggtag
    41341 gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc ttgcttggtt
    41401 tcttcgtcaa ttattatctg agaaaggttg atatgttaga agccctgaaa tctgtagagt
    41461 aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa tcctccgttt
    41521 caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta gcagctgcaa
    41581 ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg tagcgaatcg
    41641 tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg ttgatcaaga
    41701 gggcataatc gcgcccgaaa gaatggtcaa agtagtctga aagcataatg gcattgtcaa
    41761 ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa acagtcaata
    41821 cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga gttgagcaga
    41881 tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca aaatcagcca
    41941 gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg tcgccgactt
    42001 gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata ggatactcca
    42061 atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt gaccggaaat
    42121 gtgggcatag aaaaaacgcc agctcacatg agaatgacgt ttttcagagg cttattttgc
    42181 caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc tgtcgccttc
    42241 tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga tgtttgtgtc
    42301 ttgagaaaca gttttcattg gacggtcatc cacacttgat tctacaaaga gtgatggaac
    42361 ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc cttcttcttc
    42421 agtattgatt tcccagatgt aggcacttgg aacaccatag gctttagaga agtatttgaa
    42481 tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa atttatcctt
    42541 actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt tttcatagaa
    42601 ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag caaaaataat
    42661 accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat tttgaccttc
    42721 aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt cagttttctt
    42781 ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt tgataccgtt
    42841 atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg gttcgtattc
    42901 gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac cagcaatatt
    42961 tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt gaccagaagt
    43021 tgtatctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa agagaacgag
    43081 taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc ccttatttta
    43141 acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag aagctaatga
    43201 gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta aaactatagc
    43261 caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg aaaatcatgc
    43321 tttttagact attagcatac agataagcag ttgcagctgg ggtaatcagc atggctacaa
    43381 tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg agtaccatga
    43441 gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt tcatcaaagg
    43501 aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct gcccccacac
    43561 ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa aggatatgga
    43621 aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct aagaaagaag
    43681 aaaaggtaat gccgatggca gtatcgcttt tgataatcga gtttcctttg atgtaggtaa
    43741 tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca aggcccaaga
    43801 tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc atgagtgaca
    43861 tcccgcgtag aataatgaaa catcccacag ctccagctac aatcccgacg acaatagctg
    43921 ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat tctgcaatca
    43981 taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat tggtttcggt
    44041 aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta agacttgatc
    44101 gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct tcccagcttt
    44161 tttcaaatct cttagcgtat tcatgatgat ttcctcactg acagagtcaa tcccagcaaa
    44221 gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa tcaagacccg
    44281 ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag ctaggccgac
    44341 gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc gaaagagagg
    44401 aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa agttgtagtc
    44461 gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa cttccttgtc
    44521 atcgagaaat gcccgacctt gatgtgggat aattcccagc atacctttta atagtgttga
    44581 tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga gcactagtga
    44641 aatatcctta agtgccaacg tttctttgta ggagacactg agattttcga tacgtatcat
    44701 aaacttgtat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt caagttaatt
    44761 tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa agataacttt caggataaat
    44821 ttctaaatta taaaacgcat agtatcaagt gtaaaaaact tggaattatg cgttttatca
    44881 tggaaaggtt ttttataata gctaaaaaat aatagttaaa tggttattaa ttgcattccc
    44941 tagtgatttt tgttaagata aatgcaaata caaatgaaag cgagaacaag atgacacgtt
    45001 atcaagatga tttttatgat gctatcaatg gagaatggca acagacagct gaaatcccag
    45061 cagataagtc tcaaacagga ggttttgttg atttagacca ggaaattgaa gacctgatgc
    45121 tggcgacaac agacaagtgg ttagcaggtg aagaagtgcc tgaggatgct atcttggaaa
    45181 actttgtcaa ataccaccgc ctagttcgtg attttgacaa gagagaagct gacggtatca
    45241 cacctgtctt accactcctt aaagaattcc aagaattgga gacttttgcg gattttacag
    45301 ctaaactagc agagtttgag cttgcaggaa aaccaaactt ccttcctttt ggtgtatcgc
    45361 cagactttat ggatgctaga atcaatgttc tatgggctag cgctccaagc acaatcttgc
    45421 cagatacgac ctactatgca gaagaacatc ctcagcgcga agagctcttg actctttgga
    45481 aagaaagcag cgcaaatctc ctcaaggctt atgatttctc tgatgaagaa attgaagact
    45541 tgctagaaaa aagacttgaa ttggaccgcc gagttgcgac agtggtgctc tctaatgaag
    45601 aaagttcaga atatgctaaa ctctatcatc catattctta cgaagatttc aagaaattcg
    45661 cgcctgccct acctttggat gacttcttca aagcagttat tgggcaatta ccagacaagg
    45721 ttattgtaga cgaggaacgt ttctggcaag cagcagagca attctacagt gaggaagcct
    45781 ggtctctcct taaagcaacc ttgattttga gtgttgtcaa tctttcaacc agctatttaa
    45841 cagaggatat ccgtgttttg tctggtgcct acagccgtgc cctttctgga gttccagagg
    45901 caaaagataa ggtcaaagca gcttatcatc tagcacagga acctttcaag caagccctgg
    45961 ggctttggta cgcccgtgag aagttctctc cagaagccaa ggcggatgtg gagaaaaaag
    46021 tggcaaccat gattgatgtc tataaggagc gtctgcttaa gaatgactgg ctcactccag
    46081 aaacctgtaa acaggctatc gtgaagctca atgtgatcaa accttatatt ggctatccag
    46141 aagaattgcc tgcacgttac aaggataagg tagtgaatga aactgccagt ctttttgaga
    46201 atgctctagc ctttgcgcgt gtggaaatca agcacagttg gagtaagtgg aaccagcctg
    46261 tagactataa ggaatggggc atgcctgctc atatggtcaa tgcctactac aatcctcaga
    46321 agaacctgat tgtctttcca gcggccattt tacaggcgcc tttctatgac ttgcatcagt
    46381 catcttctgc taactacggt ggtattgggg cagtgattgc ccatgaaatt tcccacgcct
    46441 ttgatactaa cggggcttcc tttgacgaaa atggtagcct caaggattgg tggacagaga
    46501 gcgactatgc tgccttcaag gagaaaacac aaaaagtcat tgaccaattt gatggacagg
    46561 attcttatgg agcaaccatt aacggtaaat tgactgtatc agaaaacgtg gctgacttgg
    46621 gaggaatcgc agcagctctt gaagcagcta agagagaagc agacttctca gcagaagagt
    46681 tcttctacaa cttcggtcgc atctggcgca tgaaaggtcg accagaattt atgaaacttt
    46741 tggctagcgt cgatgtgcac gcaccagcca aactccgtgt caatgtgcaa gtaccaaact
    46801 tcgacgattt ctttacaacc tatgatgtca aagaaggaga cggaatgtgg cgttcaccag
    46861 aggagcgcgt gattatttgg taatgcaaaa aatctagtca tcagaaaaaa ggcatccaat
    46921 cacgtgtgaa aaccttgata ggatgccttt tataatagaa agatttgctg gatagtttac
    46981 ttaaatttcg attgtcatca tcttgctaaa aaaagggatt gaaggccttt tcgtgagcga
    47041 tagtagtagc tggaccatgt cctggataga catcgtagtt tggtagggtg aagagttggg
    47101 tctggatact atgaaggagt tgctccatgc taccagtcgg aaggtcggtc cgtccgatag
    47161 tttcgcggaa tagagcatct cccgtcaaga ctaggtgagc atcaggaaag actagggaaa
    47221 caccaccgat agagtgccct ggggtcggta gaaccttaaa acgaaattcc tctagttggt
    47281 attcttcgtg aaagacaaag gtgtgttctg caggttttgt gaccacatct gccatatcat
    47341 cgtggcgagg gagaccggag agattatcga caggagtgta gagccagctg gcttcgctct
    47401 ctgcgatata gacaggagga ttgccaaacg tctcgcgaac caagtccaga ctcatgatat
    47461 ggtcataatg ggcgtgggtc aagagaatag cacagatcgg tttgttgatc ttctcgattg
    47521 tctgacgaat ggcttcccaa tgactaccag gatcgacgac gatgaggtgc ttttcgcctt
    47581 ctagataata ggtattttca taggcaacag gattcacggt tttatggatt ttcatactag
    47641 ctccaatctc aaagaatgta ctaatactct tcgaaaatct cttcaaaccg cgtcaacttt
    47701 atctgcaacc tcaaagcagt gctttgaaca gcctgcggct agctttctag tttgctcttt
    47761 gattttcatt gagtataaat taagtatagc acagttaggg agaataggta aggatttaaa
    47821 atgaacttaa aaaccagcat gactagatga agacaggctg gttatcaatt tatcaatatt
    47881 ggaaaggtgt caattgccct tcataggttg cataaactcc gtcattagct tgtttgatag
    47941 acgtgatgtt tagagtgcta ccgtagttgg cttctcattt gtcgctatat tcactataag
    48001 ttatcctact gggcaggttc tggtcgttag catagtattg aacgagtttt ttatagcttt
    48061 gctggctgaa taggaacagg cagcaaactc ctaacattag gagagcaaag atagaaatag
    48121 cagttttttt cataggtatt ctccttataa actaaaggat agaagaaagt atcttgagga
    48181 tttttatact cttcaaaaat ctcttcaaac cgcgtcaacg tcgccttgcc gtatatatgt
    48241 gactgacttt gtcagtctta tctacaacct caaagcagtg ctttgagcaa cctgcggcta
    48301 gtttcctagt ttgctctttg attttcattg agtattaatt ccaaaatcca gtcaaggtac
    48361 cagtgtatgt gatacgagtt ccaccgttta tctttcgtat cttcaatgga attggggaaa
    48421 tcataaagtc tttgggttac aatatggttt ccgttcttct atctctcctt ctatcaccta
    48481 agtttaaaat ctaacttcgt agtatattat gggccaataa ttcagaatta tcaagcaatt
    48541 ttgaattatt tttttcttat tctgttccaa tctagttttc atattcttaa aaaagtgata
    48601 aaatggtagg aagaattgga gagtagagat gccgaaagaa gtgaatttaa caggcgaaga
    48661 agttgtcgct ttaaccaaag aatatttaac ggaagaggat gttcattttg tccataaggc
    48721 cttggtctat gctgttgaat gccacagtgg tcaatatcgc aaatcaggcg agccttatat
    48781 cattcaccct atccaagtgg caggtatttt agctaagcta aagctggatg ctgtaacagt
    48841 agcttgtgga ttcttgcatg atgtggtgga agatacagat gcgaccttgg acgatttgga
    48901 aagagagttt ggtcctgatg tgcgggtgat tgttgacgga gttaccaagc ttggcaaggt
    48961 cgagtacaaa tcgatcgagg agcaattagc ggaaaatcat cgcaagatgc tcatggccat
    49021 gtctgaggac atccgcgtta ttttggtcaa actgtctgac cgcttgcaca atatgcggac
    49081 cctgaaacat cttcgaaaag acaagcagga gcgtatttcc aaagaaacca tggaaatcta
    49141 tgccccactt gcccatcgtt tggggatttc cagtgtcaaa tgggaattag aagacttgtc
    49201 tttccgttat ctcaatccaa cggagtttta caagattacc catatgatga aggaaaagcg
    49261 cagggagcgt gaggccttgg tggatgaggt agtcacaaaa ttagaggagt atacgacaga
    49321 acgtcacttg aaagggaaga tttatggtcg tcccaagcat atttactcaa ttttccgcaa
    49381 aatgcaggac aagagaaaac ggtttgagga aatctatgat ctgattgcta ttcgttgtat
    49441 tttagatacc caaagtgatg tttatgccat gcttggttac gtgcatgaat tttggaaacc
    49501 gatgccaggt cgcttcaaag actatattgc caaccgcaag gccaatggtt atcagtctat
    49561 ccatacgact gtttatggac caaaagggcc gattgaattc cagattcgaa ccaaggaaat
    49621 gcacgaggtg gctgagtacg gggttgcggc tcactgggct tataagaaag gtataaaggg
    49681 gcaagttaac agcaaggaat cagctattgg aatgaactgg atcaaggaga tgatggagct
    49741 ccaagaccag gctgatgatg ctaaggaatt tgtggactct gttaaggaaa actatctggc
    49801 tgaggagatt tacgttttta ccccagatgg agctgtccgt tctcttccca aagattcagg
    49861 accgattgat tttgcctacg aaatccatac caaggtcggt gaaaaagcaa ctggtgccaa
    49921 ggtcaatggc cgcatggttc cactgacaac caagttaaag acaggggatc aggttgaaat
    49981 tatcgccaac ccgaactcct ttggacctag ccgtgactgg ctcaatatgg tcaagactag
    50041 caaggcgcgc aataagattc gccagttctt taaaaaccaa gataaggaat tgtctgtcaa
    50101 caagggtcgt gagatgctga tggctcagtt ccaagaaaat ggctatgtgg caaataaatt
    50161 tatggacaag cgccacatgg atcaagttct gcaaaagacc agttacaaga cagaagactc
    50221 cctctttgcg gccattggtt ttggggaaat cggtgcgatt accgtcttta accgtctgac
    50281 tgaaaaggaa cgccgtgagg aagagcgtgc caaggccaag gctgaggcag aggagcttgt
    50341 caaaggtggc gaggtcaagg ttgaaaataa agaaaccctc aaggtcaagc atgagggggg
    50401 agtggttatt gaaggtgctt ctggtctcct agtgcggatt gctaagtgtt gtaaccccgt
    50461 gcctggtgac gatattgttg gctacattac caagggtcgt ggtgtggcta ttcaccgtgt
    50521 ggactgtatg aacctgcgtg cccaagaaaa ctacgagcaa cgtctccttg atgtggaatg
    50581 ggaagaccag tactctagct caaataagga gtatatggcc catatcgata tctacggtct
    50641 caaccgtaca ggactgttga acgatgtact gcaagttctt tcaaatacaa ccaagaatat
    50701 ttcaacggtc aatgcccaac caaccaagga tatgaagttt gctaatatcc atgtgtcctt
    50761 cggtattgcc aacctctcta cactgactac ggttgtcgat aaaattaaga gtgtgccaga
    50821 agtttactct gtcaaacgga ccaacggcta gttgtcctag ctcttactag aaaggctatt
    50881 atgaaaatca ttatccaacg ggttaaaaaa gcccaagtga gtatagaagg ccagattcag
    50941 ggaaaaatca atcagggact tttattgctg gttggtgttg gaccagagga ccaagaggaa
    51001 gatttggact atgctgtgag aaaactggtc aatatgcgga ttttttcaga cgcagaaggc
    51061 aagatgaacc tgtctgtcaa agatattgaa ggagaaatcc tctctatttc tcagtttacc
    51121 ctctttgcgg atactaagag aggcaatcgt ccagccttta caggggcagc taaacctgat
    51181 atggcatcag acttctatga tgctttcaat caaaaattag cgcaagaagt gcccgttcag
    51241 acaggtatct ttggagcaga tatgcaggtt gagctggtta ataacggacc tgttaccatt
    51301 atcctagata ctaaaaagag ataagaaaga ccaagcccag tcggcttggt ctttcttatc
    51361 gatcataaaa tactccaaaa agaaatcggt tcttgatatg cttgggggaa gtctcttttc
    51421 aggctttggc agatgcgata ggaagggatg agatgtccta ggatgaggag agttccctga
    51481 aggaaaagtg gaatatcact taaagacacc aaggagagaa tcatcaggct atcctatagg
    51541 agaatttgta aagcaaaacg ccagaatctc ggtctaatct gggaatagag ttgactaaag
    51601 tggtcacaaa gttggtttga aagataggtc aatagcacag gatgaaagaa gatgagccaa
    51661 ccgctataaa tcaaaatcca gtcccaagta agcccccctt ttaaatgtca aaaatgccag
    51721 catgattcca tcaatgacaa ggagttgaat gattttgatg aagatgattt ttttcatgct
    51781 aaaacctcct tttccttaga gacactccca taaagagatg tgtttgtcgt aaaagtctgg
    51841 atagttttct cttaggtagt cagctgtcat ataataaaaa gtagaatggc aagcagtgat
    51901 aattgacata agagatgaaa aacgctgaga actaatgaag gctaagagaa caaaaaatag
    51961 aaaatcaatg gtgagaagcc ctaaatagta gaagcgaatc tttttattga tttgaggata
    52021 aatctcagcg aattgatgtt tgagtcggac gatcaagaga aatagcagga gtccttgagc
    52081 aaggaagaaa attaaaccag agagcaagag ccactcaaaa gatgtctcga gtctaatgat
    52141 aaaaaatgca aatagtagca aatcaataac tgcaattgct ataaaatgga ttctatagag
    52201 ttttttcatg acaagacctc cctcttttat ctaacttcat tctactctaa aagaatggga
    52261 gttacaacta aaatgataaa aatagcagag gggagattct cttaagttgg ctagtattct
    52321 ttatttgagt ttccttctat tatctaactt cttcatcatt ccagacaaat aaagctccga
    52381 ttgcattgag gatataaaag atgtatttac cgatattggc gaagtttcct tgaataccag
    52441 cttttgtcag ctgaacgaaa ttgtaaatca accaaaagcc ccactgtccc tcattgccaa
    52501 tgcattcaaa gcattggcaa tgagggacag tgcaaaggca atagttgtta cgtaggcaag
    52561 gagattcatc ttgcccccat atccgatata gttggtcaca aaggcaaaga ggaaggcgat
    52621 gatggaaatg atgatggccg ccaattttac ctgtttttgg ctcatttggt tgggtctgcc
    52681 ttcttgcgaa gctttccatt tctttatagc taaggtataa atgaggaagg tgacgggata
    52741 ggtaatgatg gccgccttat ttccaaggat ataatcaata gcaccggaca aaatggtatt
    52801 aacaatacca aagtaatttc cccgtgaaac gagtggacaa catggaaatc ctaacgttgg
    52861 ttacggaaat caatccaaag ggtacaagag ctgtccatga tccccagtct acaaatttat
    52921 cgaggtgtga gttgaggtaa ccagatgcaa tcgcaatccc aacgaccaaa gcaaccccga
    52981 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
    53041 cctttctttt tttcaaatat tctcccattt tttttcaaat attctctcac caaatgaaag
    53101 taaaatcaaa tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact
    53161 tgagaaatta gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta
    53221 aatcctcgtc gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttgactt
    53281 ggagctggtc accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat
    53341 cgtgcacccg agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat
    53401 tgatttcaac gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag
    53461 ggaaacctag cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga
    53521 cctcagcttc ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt
    53581 caatcaagcg gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta
    53641 gatagccaca ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt
    53701 cagttacggc agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat
    53761 gcaggtctat gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc
    53821 gtttcctctt gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg
    53881 tgacttttta tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat
    53941 agctcttctt tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc
    54001 tcggcagata ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg
    54061 gcgtagaagg attttggact tgttggatca actaccgatt acggctagag ttttgggaaa
    54121 ctgggaagac agtctttggc atggtgtccg taaggaattg gatagtactc gccccagtca
    54181 acgctatctc ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga
    54241 agtgctccac aatcaacctc ttcaaattca tcgtcagttt ggggatttga cggtgggaat
    54301 tagtcatcat ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga
    54361 ggattttgac cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacatattca
    54421 ccagcagttg cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg
    54481 ccaacctttc tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt
    54541 ggagtttgat gacaagggcc tggtagatat ggacttccga cgggtagact acgatgtggc
    54601 agctgaattg cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag
    54661 tctggtcaat gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa
    54721 agagggttgc gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa
    54781 ctaaaaaggg tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga
    54841 gaagaggatg caaattccaa gtagatttac cattgcgact catatgctga taatcattgc
    54901 cctcgagggg aaggaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa
    54961 tcctgtcatt atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc
    55021 gcgtggaacc ggcggaacag agattgtcaa ggaccttaag gatattagtc ttttagatgt
    55081 ttatcaggcg gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc
    55141 gaatccaaat tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag
    55201 aattcagttg actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga
    55261 tgcagagagt cagatgaagg attaagaggg ataaatgccc tctttttttc tttggataat
    55321 tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg aattgtatta
    55381 gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta
    55441 ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag
    55501 aatgttcagt tagcttttta tgtatttgcc tttgtcttac ttcctttttt gctttttcta
    55561 agtggcatct ttttaatcta taatggggtc attttgttga aacgagaggg acgttccaag
    55621 ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac
    55681 ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca
    55741 agagtattat ctatttttcc atgcatggta acgagtatca atcaataact gggtaaggcg
    55801 acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat
    55861 gtattcaagc gcctttaagg aagccaagtc attgatagag ctaataccag catcaagaat
    55921 agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca
    55981 ttctttaaag gttgtgtcta cttgccggct atcactgttg gtcttatcca gttgaacgaa
    56041 gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt
    56101 actctgaacg atgatttggt gagcaggaat ttccagcatc ataccgataa tggaaccttg
    56161 tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc
    56221 ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg
    56281 ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc cagccagaat
    56341 aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg
    56401 agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc
    56461 atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc
    56521 aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt
    56581 gaagcgcttg tgttgagcca attcatctaa taattgaagg cgatttttgc tagtaagcat
    56641 ggtgggctct cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac
    56701 cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa
    56761 gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat
    56821 aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag
    56881 cctgtttgtg ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg
    56941 aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag
    57001 atgatcaggt cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg
    57061 tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg
    57121 tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca
    57181 agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca
    57241 tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt
    57301 tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc
    57361 tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag
    57421 tcttgaattt gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca
    57481 acatcgtagc acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg
    57541 ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg
    57601 taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa
    57661 caattttttc tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttctttg
    57721 gcatttcttg tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac
    57781 tttttcttct tgtgttgctt tgtaaccata ttatttttca cttgggacat attggtggaa
    57841 acgcaggtct atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa
    57901 atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa
    57961 gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca tcagataaag
    58021 acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag
    58081 cagctagaac aggaaatttt caaaatcgac tcctatacca acctagtttt acagtacctg
    58141 cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga ggacttggtc
    58201 aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgttaatcta
    58261 catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa
    58321 atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac
    58381 caagagcttt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta
    58441 tttgaacgtg gcttttcagg atacaatgga cgtttgaccc agcagtcctc tggacttggc
    58501 ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag
    58561 gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa
    58621 aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac
    58681 gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt
    58741 ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc
    58801 tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat
    58861 tttttcattg cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggccac
    58921 ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta cttggtgtgg
    58981 tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg tgaagcgttc
    59041 catagttgag ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc
    59101 gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt
    59161 ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggctgc
    59221 ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt
    59281 ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg
    59341 aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa
    59401 ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc
    59461 gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg
    59521 gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg
    59581 tttaaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc
    59641 acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac cagaagtctt
    59701 gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc
    59761 tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg gtaaccagaa
    59821 tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt
    59881 acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt
    59941 gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca
    60001 gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacatg
    60061 aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc
    60121 ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc
    60181 ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat
    60241 ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc
    60301 gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg
    60361 acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa gggcatcttc
    60421 gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat
    60481 gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg
    60541 ggcaatttca aaagttgtta cgccagattc gaattcacga acagcgccat ctgggaaagt
    60601 aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt
    60661 atcagcagac tacttccgag tcctaacgtt caattgcttt tctttatcag agaggaagtt
    60721 ttccatttcc gtcagaatgt ctatatccaa acgttgagaa agttctaata gccaccagat
    60781 attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt
    60841 tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga ggtcttcttc
    60901 taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc
    60961 ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga
    61021 catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg
    61081 gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag
    61141 tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg
    61201 actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt
    61261 gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca
    61321 tgcccaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac tcaccaaagg
    61381 ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccaccaaagt gagaaacgga
    61441 aacggtagct atagagtaac gatataatca agattaccag aggtgtaaag aagagaagat
    61501 tgtttatata gagtcccttg agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    61561 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    61621 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    61681 tagcatgttt aaaacaagaa agtaaatttg ttgacaaaga agattttttt cactagaatc
    61741 atggttagtt ttcttggtag aaatattttg ataataatta agcaagacta ttgacattga
    61801 ttattaagag tgtcacaatt attgtaacta aaataattac aataagagag gtataaaaaa
    61861 tgaaactagc agttattgca gcaaatggac aagcggggaa agcaattgtt gaagaagtag
    61921 tcaaacgagg acatgaagta acggctattg ttcgttctga aaacaaaagt caagctgagt
    61981 ctattattaa aaaagattta tttgagttga caaaagatga tcttactgga tttgatgctg
    62041 ttatttcagc gtttggtgct tatacaccag atacgctacc gctccacagc aaatcaatcg
    62101 aactatttaa tcagcttctt gctggaacac agacacgttt tctagttata gggggagcag
    62161 gaagccttta tatagatgaa acaaaaatga cacgactttt agatacgcct gattttcctg
    62221 aagaatttaa gccactagca aaagctcaag cggatgaatt tgatcttctt cgtacaaaaa
    62281 ataatctcaa ctggactttt gtcagtcctg ctgtagattt tattcccgat ggtgaaaaaa
    62341 caggaaacta cattctagca ggagaaattt ttactactaa tggaaaagga ataagccaga
    62401 ttagttatgc agattatgct attggattgg tagatgaact tgaaaaaggt catcatataa
    62461 aagaacgtat ctctttactt gaaaaataat aactatgaga gtattaatgt ttgacagaaa
    62521 atttaaatct tggtaaaata gggattgtcg taaagacaaa taacttcttc ttggttacag
    62581 gcatgccaac ctgtcactcg gatgaagcca aataaaaagg agaaacatca tggcaatctc
    62641 aaaagagaaa aaaaatgaaa tcattgcaca atatgcacgt cacgaaggtg atacaggttc
    62701 agtagaggtt caagttgctg tccttacttg ggaaatcaac caccttaacg aacacatcaa
    62761 acaacacaaa aaagaccacg ctacttaccg tggattgatg aaaaaaatcg gtcgccgtcg
    62821 taacttgctt gcatacttgc gtaaaaacga cgttaaccgt taccgtgagt tgatcaactc
    62881 tctaggactt cgtcgctaat tcaagataca aaggccgtca aaagcacaaa gcaaaaatag
    62941 gaaaattgac gaagaaactt cagtttctag gagattttat cttttttgcc aagtgcttag
    63001 gccgtgttca attgagcata tcttgataat aaagctactc taaattgggt agctttgttg
    63061 cgttgtcacc ttacctcgct atactcaagt ataatcttcg gttacggttc ctagcactgt
    63121 aaggtaaaat aaactagctt ttctcccttc gtggagattt ttttgtttca ctgaaagttt
    63181 cgtacgatct tcacctcgtc ccctagtcta taaacgattt atctagcaag aatcatgatg
    63241 ctaagggtgt caaaaatccg tatgaaaata gggaaatgac acagtgttcg atgagcacaa
    63301 ggagtttcat ctttttcact aggattttag cccgggctaa aatcagctct ctgacttcag
    63361 agggcttttt tattgaggtt ttatcggtaa caattttgga gactacaaaa atctcaaatg
    63421 gtatcagcta attacaccat aaaggtgcgc agctactcgg cttttcaagc cgagtagctg
    63481 tatgcaagcc ccctagaaga gcccactctt tacaaagtaa agtatagtat gttatacttt
    63541 acatggaagt agtcactgaa ttccagttag aaattacttt gtaactacgt tttgaggagg
    63601 agtaaaatgc tttcctacgt tcgacattac ccactagcga tagctaaatt aatgtgtttg
    63661 tgctctccta aaatctgctg atttattact gactaataca ggaggttttt tttatgggac
    63721 agacaatcat atctgctatt ggtgtttata tttccaccag tatcgattat ttaattattt
    63781 taattatttt atttgcacag ctatcacaga ataaacagaa atggcatatt tatgcggggc
    63841 aatatctagg cacaggctta cttgtagggg cgagtttagt tgctgcttat gtcgttaatt
    63901 tcgtgcctga agaatggatg gttggattgc ttggtttaat ccctatctat ttagggattc
    63961 gctttgcaat tgttggagaa gatgcggaag aagaagagga agaaattatt caaagattag
    64021 aacaaagcaa ggcaaatcaa ctgttttgga cagttacatt gctgacaatt gcgtctggcg
    64081 gagataattt aggtatctat ataccttatt ttgcttcgtt agattggtca cagaccctcg
    64141 tggccttgct tgtgtttgta atcggcataa ttatcttttg cgagattagt agggtgttat
    64201 cctctattcc gttaatattc gagacaattg aaaaatacga gcgaatcatt gtgcccttag
    64261 tattcattct acttggacta tacatcatgt atgaaaatgg cacgatagag acttttctga
    64321 tcgtgtagat ttttttgttt cactaggatt ttagcctgag ctcaaatcag ctctctgatt
    64381 ttcagagggc tttttcattg agtataaatg gacaatctta aagttactct attgtagagt
    64441 ggcttttgat ttgattaggg gattcttata aatatagtaa aatgaaataa gaataggaca
    64501 aaatcgatca ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat
    64561 tctagttcca atctactata taaatgaaaa ccttagctgt ttggccaagg ttcatttctt
    64621 ctatgcaagt tcttctcttt tcttatctgg gttccagatg aagcttgcga taaagctaaa
    64681 gatgatggtt aggatagcga ggataatagc aaggatgagg gcagggatgc ggataaacca
    64741 ccagagtgga tttggttttt tatcattgtg ccattgtttc gtttcttcgt ccagacgttg
    64801 gaattctgtt tgaatacgat tggcgactgt ttcaatgcct tcatcattca ttttcttgat
    64861 atctgagata tcgattggat ttccaaagtt catatcgaca cgttcacggc taatcaagcc
    64921 cttcaaagtc atgggaccgg tgtaggtaac cggcatgata cggaccttgg ccattttggc
    64981 aatcagtgct gcgcccccct tgacatcgtt tgagtggcgg ctaccacttg gaaacatgat
    65041 gagagagcgg tcactttttt tgagaacgtt gataggatat ttgatggctg aggcgctggg
    65101 attttcacgg ttgatgggaa aggcgccaca catacgaatc caccaaccaa agatacggtt
    65161 ggtaaagagt tctttttttg ccataaagat gaactgtttt ggcttggtcg caaaggccat
    65221 ataaacagga tcccaccagg tacggtgagg cgcaactaaa atataatttt catcttgatt
    65281 aggaatttta tcagtattat gatagtgagc attgccattg atggaccata agagcaatac
    65341 aactaatcca cgcaaataag tataaaacat gcgatctcct tcgattgttt tcttgttatt
    65401 attatacctt atcaaaggag ggctggcaaa cttttccctt gactagatgc atatttggga
    65461 tgaaattaga attctgttaa aaaaaatgat ataatagaat ttatggataa aaataagatt
    65521 atgggattaa cccaaagaga agtcaaggaa agacaggctg agggtttggt caatgacttt
    65581 accgcatcag ccagtaccag cacttggcaa atcgttaaac gaaatgtctt tacccttttt
    65641 aacgctttga actttgccat tgctttggcc cttgcctttg tgcaggcttg gagcaatctg
    65701 gtcttctttg ctgttatctg ctttaacgct ttttctggga ttgtgaccga gctacgagcc
    65761 aaacacatgg tggacaagct caatctcatg accaaggaaa aggtcaaaac catccgtgat
    65821 ggtcaggaag ttgctcttaa tcctgaagaa ttagtgctag gagatgtcat tcgtttgtct
    65881 gcaggagagc agattcctag tgatgccttg gttttggaag gctttgcgga agtcaatgaa
    65941 gccatgttaa cgggagaaag tgatttggtg caaaaggaag ttgacaactt acttttgtca
    66001 ggaagtttct tggctagtgg gtcagtttta gctcgtgtcc atcatgtagg tgcagacaac
    66061 tatgccgcca aacttatgct ggaagccaag accgttaaac ccatcaactc ccgtatcatg
    66121 aaatcgctgg acaagctagc aggttttact gggaagatta tcattccctt tggtctggct
    66181 ctcttgctgg aagccttgct tttaaaaggc ctgcctctca agtcatctgt tgtaaattcg
    66241 tcgacagccc ttttgggaat gttgcctaag ggaattgccc ttttgactat tacttcgctc
    66301 ttgactgcag tgattaagct tggcttgaaa aaggtcttgg tgcaggagat gtactctgtt
    66361 gagaccttgg cgcgcgtgga tatgctctgt ctggacaaga cgggcaccat cacccaagga
    66421 aagatgcagg tggaggctgt tcttccactg acggaaactt acggtgaaga ggctattgcc
    66481 agcatcttga ctagctacat ggcccatagt gaggataaga atccaactgc ccaagccatt
    66541 cgccagcgtt ttgtgggaga tgttgcttat cctatgattt ccaatcttcc cttctcgagc
    66601 gaccgcaagt ggggggctat ggagttagaa ggcttgggga cagttttctt aggggcacct
    66661 gagatgttgc tggattctga agtcccagaa gccagggagg ccttggagag aggatcacgt
    66721 gtcttggtct tagctctcag tcaggagaaa ttagaccatc acaaaccaca gaaaccatct
    66781 gatattcagg ctctagcctt gctggaaatc ttggacccca ttcgagaggg agcagcagag
    66841 acgctggact atctccgttc tcaggaggtg ggactcaaga ttatctctgg tgacaatcca
    66901 gttacggtgt ccagcattgc ccagaaggct ggttttgcgg actatcatag ctatgtagat
    66961 tgctcaaaaa tcaccgatga ggaattgatg gccatggcgg aggagacagc tattttcgga
    67021 cgtgtttccc ctcatcaaaa gaaactcatc atccaaacgt tgaaaaaagc gggtcataca
    67081 acggctatga caggggacgg ggttaatgat atcttggccc ttcgtgaggc ggattgttct
    67141 atcgtgatgg cggaggggga tccagcaacc cgtcagattg ccaatctggt tctcttgaac
    67201 tcagacttta atgatgttcc tgagattctc ttcgagggtc gtcgcgtggt caataacatt
    67261 gcccacatcg ccccgatttt cttgataaag accatctact cattcttgct cgcagttatc
    67321 tgtatcgcca gtgctttact aggtcggtct gaatggatct tgattttccc cttcattcca
    67381 atccagatta ccatgattga ccagtttgtg gaaggtttcc caccattcgt tctgactttt
    67441 gagcgaaata tcaaacctgt tgagccaaat ttcctcagaa aatccatgct tcgtgcccta
    67501 ccaagcgctc tcatggtcgt cttcagcgtc ctgtttgtga aaatatttgg gagtagccaa
    67561 ggttggtctg agttagaaat ctcaactcta ctctattatc tcttggggtc aattggtttc
    67621 ttatccgtat ttagagcctg catgccattt accctatggc gtgtcctctt gattgtttgg
    67681 tcagtaggag gtttcctagc cacagctctc ttcccaagaa tccaaaaact gcttgaaatt
    67741 tcaaccttaa caggacaaac attacctgtt tatggtgtca tgatgttggt ctttaccgtg
    67801 attttcatcc tgaccagtcg ttaccaagcg aaaaaataaa gaaagactgc aatctgtgga
    67861 ttgcagtttt ttatacgatg gatctatcgt agatctgatg tgcaaggcct acgtgccgat
    67921 catctatcgg tgaacacaag agtgattctc aagcctgctt ggattgaggt aatagattca
    67981 aatatctgta gttagactat ttgaagtttg atgtaagaaa gagaaagcga cagattgaag
    68041 taattttaac tctcttctat tgctagaaca aatggtcgga taagttggta gtttgaaaat
    68101 gaagatgcta tctattgtta aatggaacat agtgttattt attagaaaat cgtttggttt
    68161 atttcttatc aaatatgaaa agcaacttaa atatttcaac taaaatagat gttatgaaga
    68221 aaaggtaaaa tgattttggc atagtgaggt tctgttctat ttgatatcat atttttgata
    68281 aaaacaaaaa tgtccattgc aaaggacaaa atgcgaagta tattattttt tgaaagcgat
    68341 ataatggaat cataaaggag gtgtatcgtg tctagaaaac aagaacaaat ggaaacgttg
    68401 ttgctccttt tgcgagatag taaggattat atatctgcta aagtattggg agaaaaatta
    68461 aattgctctg ataaaacggt ttatcgcctt gtcaagggaa tcaacaaaga ttgtccggta
    68521 gaagcattca ttttatctga aaaaggcaga ggtttcaaat taaatccaag aagttccctc
    68581 gtggacgttg atgggaattt tacagaggct tttgatcctg aagtaaggcg tgaaaaatta
    68641 ctagaacgtc tcttgttgac tgctcctaag ccacattcta tttatgattt aggagaggaa
    68701 ttctacgtaa gcgagtcagt agtactaaaa gatcgtcaga tattacaaga gagtctagca
    68761 atttatgggt tagatttaaa aatgagacaa cgaaagcttt ttattgatgg ggatgaggct
    68821 caaattcgtt cagccattct aaatctactg ccaatgttta atcagttgga tttagagcaa
    68881 attacacaga ataaggttca gcctcttgac ggagaacttg ctcacttttg tttgggatta
    68941 ctgattacac ttgagagaga attgggggta aacattctct atccatataa tataaatatt
    69001 ttctctcacc tgtatatttt tatcagtagg aatcgtcgta gtactagtat tcatgttgta
    69061 gcaccttcaa aacctactat tgttgatgag aaaatttaca gtgtctgtca aaaaattatt
    69121 caagaaattg aacaatattt taggatgaag gttgatgcag ttgagattga ctatctttat
    69181 caatacgttg tatcttcgag attgcaaaaa ccattttctt ccgggaagct tcctttttct
    69241 cagcgagttt tagatgtcac tcattactat tttagccgta tgtgtatgga caatagagag
    69301 attgaaacga cagatcctga ctttgttgac ttggcgagtc atatcagtcc cttactgagg
    69361 agattagata atagagtaca gattaagaat agtcttttat cacaaattct tttaacctat
    69421 cctaatctgg ttaaagagtt aacaactatt tctaaagaag tgagtctagt atttggtttt
    69481 gcgtccttga gtctggacga gattggtttt ctagtcttat attttgcacg gtttcaagaa
    69541 aagcgagcac gtcctctaaa aacagtagtg atgtgtacat caggtgtcgg aacttcagag
    69601 cttttacgag cacgattaga aaagcaattt tctgaattgg atattattga tgtagttgct
    69661 tatcatcaat tagatgagct gataaatcta tatccagatt tagatttcat tgtgacgacg
    69721 gtagctttgc aggaaccagc aagtgtcccg tttgtcctag ttagtgcttt tctaaccgag
    69781 ggtgataaac aacgtcttca agcaaaaatt caggagataa actatgaata atctttcgct
    69841 tgtccttatg gatatatctg ttcaaaatcg tcaagaagcc tacaaagaat tagcaaatca
    69901 aatcagcctt cttgtttctg aagatacaga aaaaatagaa gagcttctat attaccgtga
    69961 gagacaggga agtatagagg ttgctaaagg tgttcttcta ccacattgtg aaggaaactt
    70021 tcaacatcat gtcttagtga ttactagatt aaaaccacct atcagagaat ggtcgaagga
    70081 tatccagtgt gttgacctta ttatcggttt ggccattgca gtatcacagg acaagtcatg
    70141 tattaaaaca ttgatgagaa gactagcaga tgaatcattc ataaatcaat taaaacagtt
    70201 aacaaaagaa gaattacggg agataatata tggaaatcaa agatattctt aatgtgagtc
    70261 tgatccagac ggatttacag atgcagagca aagaagaggt ttttgaggca ttagctcaac
    70321 tattggttga gacgggttat gtgtctgata gagaccaatt tatcgaaggt ctttatcaga
    70381 gagaggcaga aggacagacc ggtattggga attatattgc tattccccat agcaagagtt
    70441 ctgctgtgga gaaggcgggg gtagtcatag ctataaatca caatgagatt ccttgggaga
    70501 ccattgatgg gaaaggggtc aaagtaattg tactctttgc agttggtgat gatacagaag
    70561 ctgctaggga gcatttgaag accttatcac tctttgctcg aaaacttggt aatgacgaag
    70621 ttgttgccaa attagttcgg gctcagacat ctgatgatgt gattgcagct ttttgttaat
    70681 aagaaaaaat tttggagggt atccgtatga aaattgttgg tgttgcagct tgtactgtgg
    70741 gaattgccca cacttatatt gcacaggaaa aattagagaa tgccgcaaag gtagctggac
    70801 atgtgattca tgttgagact caggggacaa taggggtaga aaatgaattg agtcaagagc
    70861 agattgatgc agcggatgta gttattttag cagttgatgt taagatttct ggtatggaac
    70921 gctttgaggg taaaaagatt atcaaggttc caacagaagt ggcagtcaaa tctcccaata
    70981 aactgattgc taaagctgtt gagattgtta cgaaataact gaaaatattt aaggagaaaa
    71041 tatatgttga aacacttaaa cttaaaaggt cacttattga cagccatttc ctatatgatt
    71101 ccaattgttt gtggtgcagg attcttagtt gccattggtt tagcaatggg gggtggtgtt
    71161 cctgacgctc ttgtagcagg aaaattcact atctggaatg ctttagcaac tatgggtggt
    71221 aaagcccttg gtctcttgcc agttgttatt gctacaggtt tgtcttactc gattgctggt
    71281 aagccaggga ttgcaccagg ttttgttgtt ggtctaattg ccaattctgt tggttcaggg
    71341 tttatcggtg gtatcttggg aggttatata gctggtttct tggttcaagc gattattaaa
    71401 aaggtcaaag taccaaactg gattaaaggt ttaatgccaa cctt
//
LOCUS       DAVDFK010000006        69245 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.06, whole genome shotgun sequence.
ACCESSION   DAVDFK010000006 DAVDFK010000000
VERSION     DAVDFK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.06"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(98..268)
                     /locus_tag="VUR04_000459"
     CDS             complement(98..268)
                     /locus_tag="VUR04_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340411.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(281..859)
                     /locus_tag="VUR04_000460"
                     /pseudo
     CDS             complement(281..859)
                     /locus_tag="VUR04_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(876..1139)
                     /locus_tag="VUR04_000461"
                     /pseudo
     CDS             complement(876..1139)
                     /locus_tag="VUR04_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1138..1425
                     /locus_tag="VUR04_000462"
                     /pseudo
     CDS             1138..1425
                     /locus_tag="VUR04_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1724..1942)
                     /locus_tag="VUR04_000463"
                     /pseudo
     CDS             complement(1724..1942)
                     /locus_tag="VUR04_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2739..2876)
                     /locus_tag="VUR04_000464"
     CDS             complement(2739..2876)
                     /locus_tag="VUR04_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET5340412.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(3077..3664)
                     /locus_tag="VUR04_000465"
     CDS             complement(3077..3664)
                     /locus_tag="VUR04_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5340413.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQARKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGIFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            complement(3667..3900)
                     /locus_tag="VUR04_000466"
     CDS             complement(3667..3900)
                     /locus_tag="VUR04_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5340414.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     ILHYKMEQRMPQSPWVERIVQVLDLDYEDLFRK"
     gene            complement(3913..4293)
                     /locus_tag="VUR04_000467"
     CDS             complement(3913..4293)
                     /locus_tag="VUR04_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET5340415.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(4286..4735)
                     /locus_tag="VUR04_000468"
     CDS             complement(4286..4735)
                     /locus_tag="VUR04_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340416.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYEPYLQNVMEFLESQDIKNGVDASVDDHQNLVFILYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(4719..5467)
                     /locus_tag="VUR04_000469"
                     /pseudo
     CDS             complement(4719..5467)
                     /locus_tag="VUR04_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842088.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            complement(5571..6074)
                     /gene="dcm"
                     /locus_tag="VUR04_000470"
     CDS             complement(5571..6074)
                     /gene="dcm"
                     /locus_tag="VUR04_000470"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET5340417.1"
                     /translation="MKFLDLFAGIGGFRMGMEAQGHECLGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     GVYYRTF"
     gene            complement(6223..6998)
                     /locus_tag="VUR04_000471"
                     /pseudo
     CDS             complement(6223..6998)
                     /locus_tag="VUR04_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(6995..7168)
                     /locus_tag="VUR04_000472"
     CDS             complement(6995..7168)
                     /locus_tag="VUR04_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340418.1"
                     /translation="MTKELQLSRYIVISFLVREMGIDIVKAISLMAELEKSGLVRLES
                     SGDLILKELGGEL"
     gene            complement(7369..7737)
                     /gene="rplL"
                     /locus_tag="VUR04_000473"
     CDS             complement(7369..7737)
                     /gene="rplL"
                     /locus_tag="VUR04_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET5340419.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(7813..8313)
                     /locus_tag="VUR04_000474"
     CDS             complement(7813..8313)
                     /locus_tag="VUR04_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET5340420.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(8352..8487)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(8562..9821)
                     /locus_tag="VUR04_000475"
     CDS             complement(8562..9821)
                     /locus_tag="VUR04_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET5340421.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPSFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFFEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(10169..11917)
                     /locus_tag="VUR04_000476"
     CDS             complement(10169..11917)
                     /locus_tag="VUR04_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340422.1"
                     /translation="MKRQTVNQTLKRLALDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKNLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLIDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(11919..13643)
                     /locus_tag="VUR04_000477"
     CDS             complement(11919..13643)
                     /locus_tag="VUR04_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340423.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLLPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTFLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(13701..14639)
                     /gene="msrB"
                     /locus_tag="VUR04_000478"
     CDS             complement(13701..14639)
                     /gene="msrB"
                     /locus_tag="VUR04_000478"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET5340424.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEKERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(14934..15803)
                     /locus_tag="VUR04_000479"
     CDS             complement(14934..15803)
                     /locus_tag="VUR04_000479"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET5340425.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(15805..17091)
                     /locus_tag="VUR04_000480"
     CDS             complement(15805..17091)
                     /locus_tag="VUR04_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET5340426.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMN
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(17242..17979)
                     /gene="mecA"
                     /locus_tag="VUR04_000481"
     CDS             complement(17242..17979)
                     /gene="mecA"
                     /locus_tag="VUR04_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET5340427.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(18179..19213)
                     /locus_tag="VUR04_000482"
     CDS             complement(18179..19213)
                     /locus_tag="VUR04_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET5340428.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(19242..20675)
                     /locus_tag="VUR04_000483"
     CDS             complement(19242..20675)
                     /locus_tag="VUR04_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET5340429.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(20691..21677)
                     /locus_tag="VUR04_000484"
     CDS             complement(20691..21677)
                     /locus_tag="VUR04_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5340430.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(21679..22782)
                     /locus_tag="VUR04_000485"
     CDS             complement(21679..22782)
                     /locus_tag="VUR04_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET5340431.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(22772..23617)
                     /locus_tag="VUR04_000486"
     CDS             complement(22772..23617)
                     /locus_tag="VUR04_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5340432.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLAPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTKMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(23896..25170)
                     /gene="psr"
                     /locus_tag="VUR04_000487"
     CDS             complement(23896..25170)
                     /gene="psr"
                     /locus_tag="VUR04_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET5340433.1"
                     /translation="MSKENPLSHHEKLRYDYLLKNIHYLNEREKNEFAYLQEKITLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALVMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(25167..26015)
                     /gene="pheA"
                     /locus_tag="VUR04_000488"
     CDS             complement(25167..26015)
                     /gene="pheA"
                     /locus_tag="VUR04_000488"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET5340434.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQARIQAVAEIVQPIHQQLMVVPGYTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKVLGAYPIYPISD
                     HGKERR"
     gene            complement(26012..26488)
                     /locus_tag="VUR04_000489"
     CDS             complement(26012..26488)
                     /locus_tag="VUR04_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET5340435.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVIISQRNRDLLKTNSDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELAAIFQERQAWYEEVAIRVLDVTKLSPEEIIEELR"
     gene            complement(26481..27764)
                     /gene="aroA"
                     /locus_tag="VUR04_000490"
     CDS             complement(26481..27764)
                     /gene="aroA"
                     /locus_tag="VUR04_000490"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET5340436.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(27856..28194)
                     /locus_tag="VUR04_000491"
     CDS             complement(27856..28194)
                     /locus_tag="VUR04_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET5340437.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(28205..29308)
                     /locus_tag="VUR04_000492"
     CDS             complement(28205..29308)
                     /locus_tag="VUR04_000492"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET5340438.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEYLITENTDYTVVIK"
     gene            complement(29318..30484)
                     /gene="aroC"
                     /locus_tag="VUR04_000493"
     CDS             complement(29318..30484)
                     /gene="aroC"
                     /locus_tag="VUR04_000493"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET5340439.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(30494..31561)
                     /locus_tag="VUR04_000494"
     CDS             complement(30494..31561)
                     /locus_tag="VUR04_000494"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET5340440.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(31580..32434)
                     /locus_tag="VUR04_000495"
     CDS             complement(31580..32434)
                     /locus_tag="VUR04_000495"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET5340441.1"
                     /translation="MKLDGYTRLTAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(32424..33101)
                     /locus_tag="VUR04_000496"
     CDS             complement(32424..33101)
                     /locus_tag="VUR04_000496"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET5340442.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(33098..34261)
                     /locus_tag="VUR04_000497"
     CDS             complement(33098..34261)
                     /locus_tag="VUR04_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET5340443.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSFEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(34948..36582)
                     /locus_tag="VUR04_000498"
     CDS             complement(34948..36582)
                     /locus_tag="VUR04_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340444.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(36563..37312)
                     /locus_tag="VUR04_000499"
     CDS             complement(36563..37312)
                     /locus_tag="VUR04_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340445.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            37491..38945
                     /locus_tag="VUR04_000500"
     CDS             37491..38945
                     /locus_tag="VUR04_000500"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET5340446.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLIELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(39035..41653)
                     /gene="alaS"
                     /locus_tag="VUR04_000501"
     CDS             complement(39035..41653)
                     /gene="alaS"
                     /locus_tag="VUR04_000501"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET5340447.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(41675..42160)
                     /locus_tag="VUR04_000502"
     CDS             complement(41675..42160)
                     /locus_tag="VUR04_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET5340448.1"
                     /translation="MKIFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(42435..42674)
                     /locus_tag="VUR04_000503"
     CDS             complement(42435..42674)
                     /locus_tag="VUR04_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340449.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(42943..44013)
                     /locus_tag="VUR04_000504"
     CDS             complement(42943..44013)
                     /locus_tag="VUR04_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5340450.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDSGNKFSIPYFWGTLGIVYNETMVYEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(44010..44783)
                     /locus_tag="VUR04_000505"
     CDS             complement(44010..44783)
                     /locus_tag="VUR04_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340451.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGNDMNSFTGFSLSH
                     FKTMFGDGRLMLIVTQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(44780..45586)
                     /locus_tag="VUR04_000506"
     CDS             complement(44780..45586)
                     /locus_tag="VUR04_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340452.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVALLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDIDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(45567..46724)
                     /locus_tag="VUR04_000507"
     CDS             complement(45567..46724)
                     /locus_tag="VUR04_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340453.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(46783..47733)
                     /gene="murB"
                     /locus_tag="VUR04_000508"
     CDS             complement(46783..47733)
                     /gene="murB"
                     /locus_tag="VUR04_000508"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET5340454.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(47845..48602)
                     /locus_tag="VUR04_000509"
                     /pseudo
     CDS             complement(47845..48602)
                     /locus_tag="VUR04_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(48612..49343)
                     /gene="budA"
                     /locus_tag="VUR04_000510"
     CDS             complement(48612..49343)
                     /gene="budA"
                     /locus_tag="VUR04_000510"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET5340455.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            49485..50756
                     /locus_tag="VUR04_000511"
     CDS             49485..50756
                     /locus_tag="VUR04_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET5340456.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCINETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(50776..51591)
                     /locus_tag="VUR04_000512"
     CDS             complement(50776..51591)
                     /locus_tag="VUR04_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5340457.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTNLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLERAASLTEVEE"
     gene            complement(51748..52401)
                     /gene="phoU"
                     /locus_tag="VUR04_000513"
     CDS             complement(51748..52401)
                     /gene="phoU"
                     /locus_tag="VUR04_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET5340458.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(52413..53171)
                     /gene="pstB"
                     /locus_tag="VUR04_000514"
     CDS             complement(52413..53171)
                     /gene="pstB"
                     /locus_tag="VUR04_000514"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5340459.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(53184..53987)
                     /gene="pstB"
                     /locus_tag="VUR04_000515"
     CDS             complement(53184..53987)
                     /gene="pstB"
                     /locus_tag="VUR04_000515"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5340460.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(53998..54882)
                     /gene="pstA"
                     /locus_tag="VUR04_000516"
     CDS             complement(53998..54882)
                     /gene="pstA"
                     /locus_tag="VUR04_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET5340461.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(54872..55789)
                     /gene="pstC"
                     /locus_tag="VUR04_000517"
     CDS             complement(54872..55789)
                     /gene="pstC"
                     /locus_tag="VUR04_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET5340462.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(55789..56667)
                     /gene="pstS"
                     /locus_tag="VUR04_000518"
     CDS             complement(55789..56667)
                     /gene="pstS"
                     /locus_tag="VUR04_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET5340463.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIANKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(57241..58545)
                     /locus_tag="VUR04_000519"
     CDS             complement(57241..58545)
                     /locus_tag="VUR04_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET5340464.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYATGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(58546..59319)
                     /locus_tag="VUR04_000520"
     CDS             complement(58546..59319)
                     /locus_tag="VUR04_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET5340465.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRSLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(59309..59587)
                     /locus_tag="VUR04_000521"
     CDS             complement(59309..59587)
                     /locus_tag="VUR04_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET5340466.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(59587..59988)
                     /locus_tag="VUR04_000522"
     CDS             complement(59587..59988)
                     /locus_tag="VUR04_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET5340467.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(60198..60815)
                     /locus_tag="VUR04_000523"
     CDS             complement(60198..60815)
                     /locus_tag="VUR04_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET5340468.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLAQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(60805..61578)
                     /locus_tag="VUR04_000524"
     CDS             complement(60805..61578)
                     /locus_tag="VUR04_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET5340469.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(61589..62326)
                     /locus_tag="VUR04_000525"
     CDS             complement(61589..62326)
                     /locus_tag="VUR04_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET5340470.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(62331..63461)
                     /locus_tag="VUR04_000526"
     CDS             complement(62331..63461)
                     /locus_tag="VUR04_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET5340471.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLYVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(63545..63934)
                     /locus_tag="VUR04_000527"
     CDS             complement(63545..63934)
                     /locus_tag="VUR04_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET5340472.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYALQATEASKNQL
                     NNFKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(63950..64333)
                     /locus_tag="VUR04_000528"
     CDS             complement(63950..64333)
                     /locus_tag="VUR04_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET5340473.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(64334..65122)
                     /locus_tag="VUR04_000529"
     CDS             complement(64334..65122)
                     /locus_tag="VUR04_000529"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET5340474.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGFRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(65115..66050)
                     /locus_tag="VUR04_000530"
     CDS             complement(65115..66050)
                     /locus_tag="VUR04_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET5340475.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(66180..66356)
                     /locus_tag="VUR04_000531"
     CDS             complement(66180..66356)
                     /locus_tag="VUR04_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET5340476.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(66496..67203)
                     /locus_tag="VUR04_000532"
     CDS             complement(66496..67203)
                     /locus_tag="VUR04_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET5340477.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQFYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            67354..68382
                     /gene="queA"
                     /locus_tag="VUR04_000533"
     CDS             67354..68382
                     /gene="queA"
                     /locus_tag="VUR04_000533"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET5340478.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGSHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFYGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(69043..>69245)
                     /locus_tag="VUR04_000534"
     CDS             complement(69043..>69245)
                     /locus_tag="VUR04_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5340479.1"
                     /translation="NTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWYYVNAS
                     GELAVNTSIDGYRVNDNGEWVR"
BASE COUNT        20655 a        15536 c        12726 g        20328 t
ORIGIN      
        1 tgttatgaat aacttcaata tctttaaagc tttttgttag atttataatt tcaactatag
       61 ccatctctac tccttagttt acagcaaaaa attatgctta attcttattg tttttgtaaa
      121 caatcagcga acccaatact attccattca ataagcctaa agaaatacca tattcaactg
      181 gaaaatctaa aaaaattgca aacactattc caatcatcac ccctagtgag gctgttgtta
      241 aaattacata ttcattttct ttcttcattt tctttacacc tcatttcctt tttgtatata
      301 agctgtagta ctctccacca agatccatta agtacttatg atttcctgac tcaacaatct
      361 taccaccttt cattacaaca ataatatccg catccttaat cgttgacaat ctatgagcta
      421 caattatttg agtacagccc tgacttttta tatactttgt tattctttcc tcattaatag
      481 tgtctaaagc actagttgct tcatctaaaa ttacaatact aggattattt attaatgcac
      541 gtgccagtgc tatccgttgt ctttgaccac ctgaaatatt tgaacccatc tctgagatga
      601 tagtattaaa tttcatcggc atagccatga tttcatcata gatttgaact gctttacaaa
      661 cttcctctat cttttgtgaa gtaacttcgt gctttaaagt tatgttatca agaatacttc
      721 tgttcaataa aaacgaatcc tgtggaacta ctcctaaatt ttgacttaat atttttttat
      781 ctatttgatt aatatttaca ccatcaaata aaacttttcc tgtatcaatc ttatataatc
      841 ctgatggtat ttttgataat agacttcctg caaaactaga atcctagttc atgattgata
      901 ataccagcac tcaaattcat tcgtaatcca aagcgtttac gatgatttcg ataggttgtt
      961 gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct tctctcctta
     1021 gatagcgcat ggttataggc tttatcttca actgttagcg gcttgagttt gctggattta
     1081 cgtggagttt gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaaa
     1141 ctttcacaag cttatccaga tgattatatt ttactcgtta tggacaatgc tatatggcat
     1201 aaatcaagta ccttaaagat tccgactaat attggctttg catttattcc tccatacaca
     1261 ccagagatga accccattga acaagtgtgg aaagagattc gtaaacgtgg atttaagaat
     1321 aaagcctttc gaactttgga agatgtcata caaggactgg agaaggaggt gataaagtcc
     1381 atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtgtt acttgcttta
     1441 taattcatag gtttattgta gcatattttg tttcgctggg agtctattat acaacatttg
     1501 ttaagcgttt tctacaattc gctatttttt gaatcaattt tcaaaaatca ttatatttct
     1561 ctcccaacct aaaagtactt tcagaacatt acccatagat ttttattatt tcctcaatgt
     1621 tttattacat aagtttatat ctaataattt tttatttaat atatttatta taaaatttaa
     1681 taagattcca cgtttctaat aattatactc gtggtgttag ttactttatt gacttgacaa
     1741 cctgcagtag atctctcgaa taaggttctc gaagagtaac ttctactgct ttcccatcaa
     1801 agataccaac acgtttaaat tcaatgtagt cttttttgag atgtcctaag cccataccaa
     1861 aaggaaagtg atgaatcaat tggatggtac aaccaccttt atttcccatt tgtttcaaat
     1921 catacaagtt tactaccttc atgattaact cctttatcta gtttgtcgca tcgtttgagt
     1981 ctggaaacga taaactccgt gtctgttaga aaattctcac acacgtcttg tgccagttgc
     2041 ccttcacagg gaaatactct cagtccctac ttacacaggc acgctaatca agacggagtg
     2101 gattcaattt tcaaagaaca ggtagcttta ttatagataa gagtagttga aatttttatc
     2161 acatttttta tttttctgta gagctaaatt catactaatc aaagagtttg aaataaattt
     2221 gagtattatt aactaacgtt cttcgtctaa aaatacagta gggaatattt cattctttta
     2281 tttaaaattg tctaaattcg acagaaggaa gtagcaagca ttgtcgctaa aaaaatgcat
     2341 caggttatcc tgtgcatttt tttgatatca aaataatcaa tctcctttat gagctaattc
     2401 ttctctacaa gctctttgga gcagaacaac tgtaagtata aaaaccacac ataaaatcaa
     2461 gatacttctc tcagccccaa aaacaccacc agtatataaa tcttgacccg ttaaatttgt
     2521 actgaataaa ctaaatgaaa cttttatccc actcactaat actattatat caacccacta
     2581 cagttgacaa aaagacaaac cagcctaatg actagcttgt cttcaatcaa gagaggattc
     2641 tgttcccccc cccatataag cactaacatt ccaacgtgca catattggaa cgacatccat
     2701 aactccagag aatctctaaa gtttacaatt taaatgaatt aacaattttc ccaactaaaa
     2761 gcactccagt taccgcaacg gtttgtactg aatgtactaa atcgcattcc atcaacttca
     2821 tctgtttcgt caacttgaac agatactaat tgaagattta atacttcttc tgccatagct
     2881 agctcctcct atttaaattt ttgggattaa gtactttatc caccctcata tactctctcc
     2941 accagtaaaa tgcaagtaat tatacaatgt tgtcacatag aaaataatgt ttccgtaact
     3001 tttcaaagta acttccatct ctctcccaaa actggaagtt agttttagaa gttacctaaa
     3061 aatcaggtca cctattttaa aaaagcagca aactataaac tagtaggttc cacaccaaat
     3121 gtagccccat actgccccat aagtccaatt tgtagcgtac aagccctaaa aatatcccca
     3181 gcgatacata caaacaccaa gctataatgg ttcctggatg atgtgctaag gcaaataaaa
     3241 cacttgtcaa agcaactcga atatctaatt ttctaaccaa gttccataaa atttctctat
     3301 acagaaattc ttcaaccata ctcgcattga ttaaaaacaa taaaaatgaa aaccaaggaa
     3361 cttgatgttg aagcccaatt aagtttgctt gattcgtgct ttcttgcgca tggattagac
     3421 taaaacatag acttataatc agtaggctaa cgaatccaat accaagccat ttcatcctag
     3481 atttcatatt taccttacga gcttgtttgc gttggccata catccataaa aaagaaatga
     3541 gtgacgaacc atagagaatc tgtagtatag ttaattcacc gatacaaaga aatttcaata
     3601 agtatagaga taccaatagg acatttactt gttggaatat ataaactgga attattcttt
     3661 tcatagttac ttccgaaata aatcttcata atctaaatct aatacctgca caatcctttc
     3721 tacccatgga ctttgaggca ttcgttgttc catcttgtag tggagaatct tttgatacaa
     3781 acgattcaat tcacttggat agtgaaactc tcccgcaaac atttttctgg ttaactcaat
     3841 ccagctgata tttctttcag ccaaaataat ggacaagttc tcccaaaatc gttcagccat
     3901 attacttctc ctttagttag ataaataatg tgtttgtgcc atgtaaatca attgtttcgt
     3961 atctcttggc aatagagctc tagcctcttc caaattcaga cttggataaa ctcgcttatt
     4021 tgaaaccgca agaggaagtc tgatggttag ttcaggattt tttaaaatta tctcaacgaa
     4081 atccgttaat cttagattgt cacggttctt aaatcgtaat aaattgggag ataaaaactc
     4141 aaaacaatct gaagaatagc tcatcatctc aattaattta tcctttgtca tttcagaaat
     4201 tgaatgacaa gatacctcga tgccatagtt ttggaagaag tctaaaagaa gttgatttct
     4261 ttggctattt ttacttagat agagatcaat catgggagac ctcccaaaga ttcggttcca
     4321 tttgatattc tgagacgatt aaggaatcta ataaatttgc gaaattaatc gatttcttgt
     4381 cttcatcata agcttttaca gttacttggg ttgtaagtat cccctctttt ccctcggctc
     4441 gatagccttg tccatataaa ataaaaacga gattttgatg atcatctaca gaggcatcaa
     4501 ccccattctt tatgtcttga ctttcaagga attccataac gttttgaaga tagggctcgt
     4561 aaaatagtgg gtagttgtgt tttttatggt aatcatctaa aaatgttact tcaaactcac
     4621 atggataatt gggcatcaaa aataattgtt catccagctg tttgatttct gcatcatgta
     4681 attctgtttc taattcatca caatctagta ttgattcttt atttaatgct ttcatctttt
     4741 tcctctattt cttttaattt ctttgcgatt gcggcaatca caggaacggt tacactatta
     4801 ccagcttgtt tatagagctg actattacta gagacttttc tagcagcttc aaaagcccaa
     4861 tcaggaaagc cctgcaatcg aaaacactct ttaggagtga ttcgtcgtat tctcaaacgg
     4921 taaaattgtc catctattaa aacaccagct actcggtaaa cttgtttatc ttctccttca
     4981 tagctaacca ctactactcc catttgacca ctagttgtta acgtattagc tatacctttt
     5041 ccaactctac cacgacgata ctgagaactt ggtctttcta aattgattga atccccaatc
     5101 tctgcttgag catatccttt ttcgttgctt cccgtacttt tagaaattgg attggttctg
     5161 gaattagtat tttggggatt ttatctcctc cttgcatcgt agtcagtgtt ggagataatc
     5221 cctcacttcc atagacacga cctgtctcct taaagctagt cggtaaatct ccaacaacgg
     5281 caatgccatg acgatcctga gtatttaaag taaacatcgg ctcttgattt tccttaaagc
     5341 gtctactatt ttgtcttttg tctaatctat ctggtgtcat acaaggaatc gcaactttaa
     5401 atccttctcc tttaccacga actaaggttg gcgcaaaacc ttctgaataa tagactttac
     5461 cgctcattcc actttttgat ggattcaaat ttcctaatgt ttttaaagtc tcagagttag
     5521 ttgcttgacc ttctcgtctg aaaggaaata agagtctggt acctttcttt ctagaatgtc
     5581 cgataataaa caccctctct gttttgggga acgccaaaat ccttactgtt aagcacctgc
     5641 cactcaacat caaaccccaa ctcatcaagt gtggtaagta ttgtggtgaa cgtccgtccc
     5701 ttatcgtgat tgagtaggcc tttaacattt tcaagaaaaa gaaaacgtgg ttggatttgt
     5761 ttggccgccc gagcaatttc aaagaacaaa gttcctctag tatcttcaaa tcccaatcgt
     5821 cttcctgcga ttgaaaatgc ttgacaaggg aatcccccac agatgacatc gactttccct
     5881 ctaagttttt taaattcgtc atctgaaaca tctcgtatgt catgaaattc tatttctcct
     5941 tccgtttgaa aaatggactt ataagatttc ctagcaaatt tatcaatctc acaaaatccc
     6001 aagcactcat gcccttgagc ttccattccc atcctaaagc ctcctatccc agcaaataaa
     6061 tctaaaaatt tcattattcc tctctttcca aataaaaata gccttacaat ttgtaaaact
     6121 cttgcctaac tatgatcatc catttctggt gcacggatga tttcaacaat taaaatgata
     6181 atcgaaatca gataaattcc acctagtatc caccaaatca tcttaatcac ctccctttat
     6241 ttcttgtcgt ctcagttgct tggtccactc tgacagcaca ccattaaaaa catattcagc
     6301 tatcacttcc gctgaccgag caaaccgcat ctgttctaag gcatactgat aacggccatc
     6361 aaaataaatc atggcgtagt cactagcgga ctgtgataat cctgattgtc ttacttggtc
     6421 atgaaccaaa ctccaaatat aatctctgtc atacctggtc acagcatcaa ctttgggagt
     6481 gaatatatcc ccttgtattt cagctgcaac ctgtctctcc tcctcgtcct cagtaacaaa
     6541 ttcactcctt ttcagtttca ctaatattag tctcactttc ttcagtctca ctaggggctg
     6601 aatttaaaac cggccccgtc tgaatgtaag actaggggta tctcatgttc taattcccct
     6661 aagtaaattt tattagccat acgacctttt tcactggaag actgttggac ttcatcaatt
     6721 aggccatact cacgtaaagt tttcttgatg gagagtaatt ttgacttcga acagcctaac
     6781 agcctcatca gtttagaatt agaaaatact aaatagaccg cgccttcttc atctatccaa
     6841 ccacgactga gagataattc taaacgatct tttaaaatag aataagccac ctttacttct
     6901 agtttcatat ccatatattt ttcatcctca aaaagaattt ttggtaattt ataataccgt
     6961 tctgaagttt ggtattgatt tgcggttatt cgtttcatag ctctcctcca agttctttga
     7021 gtattaaatc tccacttgat tccaagcgaa ccaagccact tttttctaat tcagccataa
     7081 gagagatggc tttaacaatg tcaattccca tttcacgtac taaaaatgaa atgacaatat
     7141 agcgtgataa ttgtaattct tttgtcattt tccctccaga aaataaaaaa aggagaacaa
     7201 tattcaactg ttctccaaaa taattttatt aaaaagaaaa accctgccaa agaatttttg
     7261 gtagggtttt tggtaggaaa ctaaataaat ttatcagttt ctaaaatgtg ttcacgattc
     7321 taaaaggctg atactatagt attccgaatt ctaattggta tatgcctctt atttaagagt
     7381 aactgaagct ccagcttctt ccaatttagc tttgatttct tcagcttctg cagttgcaac
     7441 gccttcttta acaagtgctg gtgcaccgtc aacaagttct ttagcttctt taagaccaag
     7501 accagtgatt tcacgtacaa ctttgataac gccaactttt ttgtcgcctg cagatgtcaa
     7561 ttcaacgtcg aatgaatctt tagcagcacc agcatcagca gcatcagctg cagcaacagc
     7621 tacaggagca gctgcagtta caccaaattc ttcttcgata gcttttacaa ggtcgttcaa
     7681 ttcaaggatt gaagcttctt taatttcagc aataatgttt tcaatgttca atgccattgt
     7741 tatttcctcc aaataagttt taaattttat aatagttttt ttcgtagcta ggctacgctg
     7801 tgtagcttaa gattaagccg cgtcttcttt gctttctgca accgctttga ctgcaagagc
     7861 aacgttgcgc actggcgctt gaagtacaga aaggagcata gaaagaagtc cttcgcggtt
     7921 tggaagagtt gcaagtgcaa gaatctcttc tttagatgcg acagcgcctt cgattgcacc
     7981 acctttaatt tcaagtgctt cagcgttttt agaaaagtcg ttcaagattt tcgctggtgc
     8041 gataacatct tcattagaaa atgctactgc agatggtcca acaaatacag atgcaagatc
     8101 ttcaagacca gctttttcag ctgcacgacg caagattgag tttttaataa ctttatactc
     8161 aacttcgctt ccacgaagct cacgacgaag aactgtatct tgctcaactg tcaaaccacg
     8221 agcgtctaca acgacgatag atgcagcagc tttcattttt tcagctacta cgtcaactag
     8281 ttccgctttt ttagcaataa ttgcttcact cattagtgtg ttcacctccg taattatttt
     8341 gcttggggaa tttttcaaaa agaaaaacgc gcccaaacct agacacgaaa gtacaatacg
     8401 cttcttttta catgatacgt tttgtcctcg gtaggatatt tatgagtcga gctcccctac
     8461 tgtcttaggc agttttttta aaccgtatat aagtatagca tagtcaaaaa aagaatgcaa
     8521 gatttttgca aactttttta aaatttttcg taatttttct tttaaagttc tactgtcagg
     8581 acttgacctt gcttaacaac ctgttctccg gcgatataaa catcatctac atcactagat
     8641 ttaactgcat aaaccaggtg agacagcata ttttcctgag gttggagatg aattttccct
     8701 tgtggttgaa tgaccagaaa atctgcttgc ttgccgactt ccagacttcc tatctgattt
     8761 tccattccaa ggaccttagc cccttcgatt gtcagtacct tgagagctgt ttcgattgga
     8821 aactggctgg catccccact tttcatcttc tgaagaagag ctgcagtcct tccttcctca
     8881 aacatatcta gattgttatt ggaagcaacc gagtcagtcg caattccgac tgctactccc
     8941 gctttttgga gctggataat tggagcaatt cctgatgcca gtttgaggtt actgatagga
     9001 ttgtgggcga tagccacttg agaagatgcc aagcgttcaa tttctctctc gtttaattcg
     9061 accccgtgag caaatacgga cggatgatct aaataaccca gttcttcaaa aaaagcaagg
     9121 gggcgtttgc cgtatcgttt gaggataatt cctgactcct ccttggtctc cgccacatgg
     9181 acatggagcg gaatatttag ctcttttgcc atttccaaac tcgcttccag caagtctcta
     9241 ctgcagctat acggagaatg aggtgctacc ataaccttga aatttggatt tttatatttt
     9301 aagatttcgt ctatgatgga tcgagttctg cttatagtct cagcagttgt ttctgtctct
     9361 gaagaaaaga gagtcggaga aaaataacaa cgcatcttgg aagttttcac cacctgataa
     9421 atttgctgga tatccacacc attgggatta tacatatcgt taaaggttgt tgttcctgac
     9481 tggagcatct ctgtcagggc ttctttgacc gcattggtag tcatgtcggg agtaaactca
     9541 gattctgctg gccagatata gtcattgagc cattcatgga gattgctgtc atctcggatc
     9601 cctctcagac ctgtcattgc agaatgggtg tgacaattga ccaaaccagg cataatccaa
     9661 gctccctgat agtctataat ctgctcagct tgctctaaaa acgatggctt atcttgaccg
     9721 acatagacga tttgagaatc cttgactgct aagattccat caagataaac atggaaatct
     9781 tgatcacaag tcacgatatt tacatgctga aagactttca ttataggctc cttttctaaa
     9841 agacaagttg tactcaaatt caaaccactt cagattcact ttgccgtagg tgtggttact
     9901 gacttcgtca gttctatctg caacctcaaa acagtgtttt gagctgactt cgtcagttct
     9961 atctgcaacc tcaaaacagt gttttgaact gacttcgtca gtcttatcta caacctcaaa
    10021 gctgtgcttt gagcaaccta cggctagctt cctagtttgc tctttgattt tcattgagta
    10081 ttacagtgaa caatttttct agctattgta acaaaaaagt cactcgaagg caactttttt
    10141 cgtccataaa ctttcaaaag agaatggctt attcagaact aaaagccgca gctttttgca
    10201 tttggtaata cttacccttt ctatccatga gttcttgatg gttaccatat tcaacaatat
    10261 caccatctat taagacaaga attaaatccg catcctgaat ggttgacaaa cggtgagcaa
    10321 tgatgaagct tgtgcggccc ttcatgagtt ttgcaaaggc atcctgtacc agcacttctg
    10381 tccgtgtatc aatggaagaa gttgcctcgt ctaagataag aatctttgga atagccagaa
    10441 agactcgggc tatggtcaag agctgagctt ggccgacaga gagagattct ccagcatttt
    10501 ccaacttggt atcgtatccc tgtggcaact gttggatgaa aaagtctgca ttagctgctt
    10561 tggcagcagc aattacttgc tctcgactgg cttcaggatt gccaaaggca atattatcat
    10621 gaatggtccc ttgtgtgagc caggtttctt gaagcaccat gccaaactgc tgtctcaatg
    10681 atgctcgtgt ataatcataa atggattgcc catccagcaa gatatctccc gagctaatgg
    10741 gataaaaacg cataaggaga ttgataagag ttgattttcc agcacctgtc ggaccaacga
    10801 tggctatctt actaccagct ggaatatcga tagacaagtt cttaatcaaa attttttcag
    10861 gatggtagcc aaaagagaca tgtttaaagg aaatagctcc cttaacttgg tcactggtca
    10921 agacttcctt acctgtttca gccacttcag ggctatctaa gactccatag atacgctcta
    10981 cgcaagccag agcactttgc aactcagcta gcactgaaga aatatcatta aagggcttgg
    11041 tgtattgctg aacatagttc aaaaaagtca ctaaacgacc gacggtcaag gttgaaccca
    11101 tcatgatacg ataagctcct actccagcta aaagggcata aatgagtgca tttacaaagc
    11161 gagtcgaagg attgaccgtt gaagaataaa agatggctga ctgagaatag cctgagtagt
    11221 tgtcatgagc ctcacgcaat ctttggataa attctgtttg agcattgaag gactggatta
    11281 tagtctgctg gctaagcgat tcttcaatca actgagtctg aattcccctc gtctctgttt
    11341 gcttctggaa gagatgatag gatctcttgg caataaagcg tgaaatcacc atggacagtg
    11401 gcgtcaacag caagactaag agagtcatga ggagatgaat ttggagcatg gctagaatac
    11461 taaccaaaat catcaaaaca ccaatgaaaa attggttaaa aatcatggtc aagccagctg
    11521 ccaactgttc gatgtccgtg gttacacgac taaccatctc tccactacct tgcctatcta
    11581 caaaggcaat cggtaaccga tggagtttat ggatgattcg ctcccgtaaa tctctggtat
    11641 aagagaagat tagacgatta tagaggagag gattggccca ttgtactaga gtatttccta
    11701 ttaccaccaa gagcatctgg agaaaaatct gccaaaaaac tggtgatgaa ccagccacta
    11761 ggacttggtc aatgacctgc ccaatcagaa taggtaggta aattgataag ccaacttggg
    11821 caatagttcc tagaaaggct aggaaaagga ggaagggatg gtttgctaaa tctaaggcta
    11881 aacgtttgag cgtctggttt acagtttgtc gtttcattct agtcctcctt tccatgttgg
    11941 gatgcattga tttcacgata gacttgactg gatttcatca agtcatcgtg cttgccaaca
    12001 gctagcaact cacctttttc caagaggaga atctggtccg ccatctgtaa agtcgaggtt
    12061 cgttgagaga tcaaaattaa actcatgttt ggaaaatttt ctctaatagc tttcaacagc
    12121 ttggactctg taatggtgtc cagtgctgag gtcgcatcat ctaggatgag aaacggagcc
    12181 tggcgcaaga ctgctcgtgc gatagacagc ctttgttttt gtccacctga gaaatttcgc
    12241 cctcctgctt caactagagc atccaagagt ccttccttat cactgacaaa atccttagct
    12301 tgagcaattt ccaaggcttg ccagagttct tgatcagtca cttcttgatt taaacctaaa
    12361 gtcaagttgg aacgaatagt tcccttaaag agttcgacct tttgaggtac ataggcaatc
    12421 caagaccgcc actgctccaa attaagagga ctacgtccat tttgataaag gtcaatgttc
    12481 cccttgtcta ctggataaag tccaagtaag agttgcacca agcttgattt accagaacca
    12541 gttcccccga tgatacctag aatttgtcct tgagtcatat caaaggaaat gtatctcaga
    12601 gaaggctggg ccgcatcagg ataggtaaag gtcaattctt ggacttgtaa aaccttatct
    12661 ctggtagctt gcttttgttc taactctgaa tggatatcct ctggagcctc aacaaagact
    12721 tcctcgattc gcttggctga gatataggac tggttgagag aatttatcaa catggctagc
    12781 ttgaccaatt ccaccaaaat ctgtaagagg taattgataa gagcaatgag agcaccttga
    12841 ctgagcactc ctccttgaat tgaaatatag ccttgccaga taataacgag aaaagttcca
    12901 ttgacaatca gataggtcag aggtgttaat aaactagacc agaaacctgt cttttcttgt
    12961 aatctagcat aaacttggtt aagggtttga aaaatctgta actctcgttt ttcttgacca
    13021 aaagcacgaa taacccgcat cccttgcaat tgctggcgcg tttcctgaac cagttggtcc
    13081 gttttctttc tgagactact gtagagagga ttgaccaatc gagataaccc tacaatgaca
    13141 atggtcaaaa tggcaaccat gactaagaac cagaaagtca actcagttga gattcgataa
    13201 gccataaaaa tggcaccaaa aacgataatg ggcgctcgca aaaagagacg caggaattga
    13261 ttgataccag tctgaatctg gtaggtatcc gaagtcaagc gagtgaccaa actagatgtt
    13321 gtcagacggt ctctgctgtc cttgggcaag gaaagaatat gacgataaag atcgtttgtc
    13381 aattctttag caaaacctac tgctgccttt gctgagtaaa attgagctat caaggccact
    13441 aaaacgccaa ttactgcaaa gataaggagc aggccaatct gcatccagag atgaccttga
    13501 tctccctgag gtaaagattg gtcaacaatc ccagcaatca ccatgggaag caagagctca
    13561 aaaacagctt ctaacagctt gaacaagggg gctaaaattg attccttgat gtagggtttg
    13621 aagtaagata ataggtgttt cataaatccc ttctattcat attctagaaa tgaagaaagt
    13681 gggaagcccc actctctgtt ttatttgttt aagtaaggca atagatagcc atatcctgct
    13741 ttttccatct catccttggc cacaaagcgt aaagaagcag aattgataca gtaacggagg
    13801 ccgcctaact cccgcggtcc atctgtgaaa acatgaccca agtgagcact gcctgaacga
    13861 gaacgaactt caattcgctc cattccatgg ctcagatcct tgtaataatg aatcaactct
    13921 ttggaaatcg gacggctaaa acttggccaa ccacaacctg aagcaaactt atccttggca
    13981 aaaaagagtg gctcacctgt cgtaatatct acataaatcc cctcttcaaa ggtttggtca
    14041 taggcattgg taaatggagc ctctgtagca gcttcttgtg tgacacgata agactcttca
    14101 gatagactgg ccttcaacac ctcttgacta ggcttttcat agtttgctgc atcaatcaat
    14161 ggcttatcag catcggtcac atcgatatga cagtaacctg aaggattctt cctgagatag
    14221 tcttggtggt agtcttcagc cagaatgtag tggcgtaatt gctccacttc tactgcaatc
    14281 tttcgaccca gcatgcgttc cttctcctgt accactgtgt agatagctgg caaatctgct
    14341 tcatcctgat aataaatccc agttcgatat tggcgaccac ggtcattccc ttgttgattg
    14401 atagatagag gatcgataac tcggaaataa taaagtaaaa tctctctgag tgacacttcc
    14461 ttctcatcgt aaatcacttg gaccgtttct gcatggtctg tttccttgat caactggtaa
    14521 ttggtcgttt cgacttgacc attagcgtag ccaacactgg tttctagcac tccagaaatg
    14581 cgtgaaaaat attcctctag gccccaaaaa caaccacctg ctagataaat ttctgccatc
    14641 tttatttctc ctttatcacg tttttaacta atactcttcg aaaatctctt caaaccacgt
    14701 cagcgtcacc ttaccgtata tatgttactg acttcgtcag ttctatctgc aacctcaaaa
    14761 cagtgtcttg agctgacttc ttcagttcta tccacaacct caaaacactg ttttgagcag
    14821 cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaact tcttttcaca
    14881 aaaaggatat gaaaccctct ggtcaagagt ttccccatcc tatcttctat tctttatttt
    14941 gcttctacac ggacaccttg ggtatcaact ctcaagtcat gcagttttcc tttgaaaggt
    15001 tgcttttcca attctgcctt aattgttggc atcttgtcat gagaagccag aaccataact
    15061 gtcggcccag caccagaaag gtaggttgca taggccccat tttctttggt cacttgctta
    15121 atcatcgcaa attctcttac caagtcctga cgatagcgct catggaagag gtctccctcg
    15181 attgcttgcc cagcggtcac catgtctcct gccaacaagg cagcaaccgc tacattggcg
    15241 atagaacttg cagcaacagc ttccttataa gacaattttt taggcaagac actacggctg
    15301 tcgcgagtac gtaattcata gtttggaatg taagctagaa aatcacactc tggaaagtct
    15361 gctacgatag cagagacttg cccttcaaca gaacttgcaa taacgagatt accataaatg
    15421 gctggagcca cattgtcagg atgcccttca atcttggtcg ctaactgcaa tttttcatgg
    15481 tctgataagt tgagttgacc cagttggttg gctagttcaa tcccagcaac gataaccgag
    15541 ctggaagaac ccaaaccgcg cgccaaaggg acatcactgg tcattttcaa gcgtcttggt
    15601 tgcaagtctg gtacaatttg caaagcgatt ttgagcaaga gattacgctc atcatgtgga
    15661 atccatttgc caatctggtg ttcaatcagc cactcatctc gttcttcgca gacctcaatt
    15721 tgaagatact tggttacagc tacaccgacc gagtcaaaac ctggcccgat attggcactg
    15781 gttgcaggta caataatctt catcttattc tcctagcacc ttgaaggtat tcaagaggtc
    15841 gaattctgaa accttcttca attcagctga gacattttca agctgggctt tattaatctt
    15901 gtgtgtgatg ataacgacac gcgccttgtc accctctttg ccgtcttgaa ggatttgctt
    15961 aaaggaaata tcttgagcat tgaagatttc agccaacttc aagacctgac cttttgagtc
    16021 tggagccaag attgagaaat agtagtttgc tttgacatct tcaggatttg ccaagaccaa
    16081 gtcacggcta tattcgttga agtctttgcc aatggtacca tcattcaaac gacgaacgat
    16141 acggacaata tcagctacaa cacttgttgc agttggtttt tgacccgcac ctggtccgta
    16201 gtacatagac tcaccaatac cgatagattc tacaaagaca gcgttcatta cgccattcac
    16261 actagcaagt gggtgcgctt taggtaggaa ggttggagtc acttctgcag caatacctga
    16321 agaagtttcc tcaatagaac caaccaattt cactacgtaa ccaagctctt gagctacagc
    16381 tacgtcttct ggtgtgatat tgcggattcc cttgtgggct acatcatcaa aggcaatatt
    16441 catgccaaag gcaaattggc tcaaaataac catcttgtag gctgcatcaa tcccatctac
    16501 gtcattcgtc ggatcgcttt ctgcaaatcc tagacgttgt gcttccgcaa gagcatcatc
    16561 gtaagaccag ccttcttcca ccatcttggt caccatgaag ttggaagttc cgttgactac
    16621 tccaagcacg cgcgtaattt tatcagaagc caaggaattt gctaaagtac gaagaattgg
    16681 aatcccacca gcaactgctg cttcgtagta aagtgctacc ttgttagctt gagcgatttc
    16741 tagcaattct gcgccatgga cagctaaaag gtccttgtta gcagtaacaa cgtgttttcc
    16801 agcttccaag gcacgagtga taaaggtttt agcaggctca atacgcccca tcaattccac
    16861 tacgatagta atatcctggt ctgataaaat atcatccaca ttggttacaa agttaaagtc
    16921 attccctgct gcaagcaagc gatttttttc atcttcatcc ttgaccaata ccttagcaac
    16981 tttgatatct gaatgtgctg attgattgat ttttcctcca ttttccttta ggaggaaagg
    17041 cacaccactt gcaacggtac caaatcctag taaagcaatt ttaactgtca tctttatctc
    17101 ctcgaaattt tctaatatag ccattataac agaattttgt gaaaattcct attatagtaa
    17161 atcactattt cagtataaaa agaaaaaacg aatcagacga ttcgctcttc ttaaaatctg
    17221 aaaatagctt tccagaaagg attagccgat tttttgcaga ttgagcactg catcgtgact
    17281 catcaagact tgaccatact cttgtaagac tgagcgactg atatcactat cgtctgcaaa
    17341 ctcgcgcata cgggccaaca gccaagctgg atatgggctt ggatgatttt caatatccac
    17401 taaaatggtc aaataatagc gctcgttcat tttgtagagt tcagaagttt ccatttcaaa
    17461 agtcactgtc ttggcaaaag ctaccaagtc agccaactta gcaaaagaaa ggatgtagta
    17521 gatgtaaggt tctttcttac tctcagcttc ttgttcagcc tgctcttgct cttcttcctt
    17581 ggcttcaact tgctcaagag attgaatggc ttcgatatca tccttggttt tgtctgcgat
    17641 gcttttttcc agggttttga taaattcatc tggagacatt tgagccaatt cttccatatc
    17701 tggcaaatcc gataagtctt caaaatctag attttggtca atctttgact tggtcacaaa
    17761 gacatctacc ttatcaggtt ttggagtcac acggaagctc aacatgcctg tatccagaaa
    17821 gctatcaggc atctctagct catccaagat agcataaaag aactcttctg ttttttcttg
    17881 aggaacgaga aagtcagcaa tctccattcc acgatccatc aaatcctcta aagacatcgt
    17941 gatttttaaa gttgtatcac taatttgttt cattttcatt gctagtaacc tcatactttc
    18001 agttctatct attatactag atttttacga ttttatcaaa agaaggctcc tctatacgga
    18061 tagattttcc ctagggtctt tctataggag actccaagag aaaatttctg cagacagata
    18121 gaaaaagcct tcaaaatcgg ctaagagccg attttgaaga ccttatacat cagaatactt
    18181 ataatttaaa ggttgctaca ccgaggatag aacgatttaa gtttctgaga atttgaagac
    18241 tttgctcaaa tttcttataa cgagtcactc cgtactcttc aacaagaagg actgtatctc
    18301 tttccaaaag agatgataca tcctgcaaat ctacaaaatg cattcctttt aaagcttctt
    18361 gactctgttt caatttatct aggatagctt tatttgagct aacgatggtc aattcctgtc
    18421 cagtattttt gtatgacaaa acatctgcta ggttagcaat tgttgtaatc tctgttacaa
    18481 aatcaatttg atactgagaa aaatcaccta ctctattgat tgttggatta aagagataaa
    18541 ctaacacatt tcccatcaca accaaaatca cacaaaccac tccaataaca actaaacgaa
    18601 gaatcagatt tttcacattt aagccaagcg ctgtttcacc atttgcgttc aattctttag
    18661 agttgatggt ttccagtttt tcaattttca catttgcata agcatgttta aatttctcaa
    18721 tcaacccatc aatttttttc tctaacaagt cattggcatc tttacttgat gtcaaaattt
    18781 tcacaccaac ccctgcatcg tcaatcatat agtagacggt caattttttc caccaatagt
    18841 cattcgttga atttttcaag gttgtttccg tcgtgtctaa ttcactggca atttttttca
    18901 actcactggg ttctacatca ttgaaaagat aagctccatt caaattacca tcaatcaatt
    18961 tcccataaaa atcactataa ccaccaattt gatgattcaa aatcgttttg gccgaatctt
    19021 ctggaggagt gattttatag ataagataag ttgaataact tgttgtatct ttgacagtgt
    19081 ttttattcct aactgcttta attgtaaatg gtacagcaat gagagcaaat aaagcgatga
    19141 gagctaaaat atttgctttt cgttttttat aaagatttgc aaacaaatca gctactgaat
    19201 aatgttcaaa catgattttt ttctcctttg tttagtagat actagttttc ctttgtaagc
    19261 atttttgcta caaatataat cacaagaaca attccccaga attgcattgt aaataaattg
    19321 aagaaacttt ctgaaaagct gcttcttggc ataaagaata gattattcaa gatgagtagg
    19381 gataaagcaa ataggattgt ccttgagcga taggctactt gcagcatggc tataaataat
    19441 acgccgagta agaaactaag cagaaagact ccaatcatac catagtcggt atacaactcc
    19501 atgatataac tacttccgat accatgccct ttcaagtatt ccttgttcaa gacaagatag
    19561 gatagattgt gggcataact attactatca atagctagtt ccacactatt ggttgtatgt
    19621 tcaaaggctt ttcctccgaa aatggctccc aaactccccc ttgcaaaata atcaagaaca
    19681 ggaccaaaag taaaattacg gaaatctcgg taagggaggc tactgttaaa tagaaaacct
    19741 cgagccagaa caccaaaact agttccttgt ttatagataa agtcaagtaa gatatcccag
    19801 aaacctgtat gggaaacttg gacattatcc cgtacataat taagtactcc catcgctaac
    19861 atgagaatag gagaacctac aaaaatcgct aacttttctt taaacccaat ccattttcct
    19921 ttttcagttt gctcccgcat aaagtaataa acaaaagcaa ataaaatact taaaataaag
    19981 ggatttcgtg tcccaattgc caaatgaata gtattagctg caataaagga gacaagcact
    20041 gctgtggcct gcaatttctt tggcttggtt gccagataca tacacattgc atagaccgta
    20101 aaggtagaca aaatgtaggt aaaataaggc agtttacttt caaaatttgc atagtaggca
    20161 tagtaggaag tctgcaaacg atacaagagc cgttcaaata accgaatgaa atagaaagga
    20221 taggttagaa gaaaaactcc tagtgataca aagcgtaacc gcttgatata aacctctttt
    20281 agagaatttc ctatatttgc tacttttatt ttcttcctag ctatgaagta acgagccaga
    20341 atgcctcctg tggtcaagcc cagaatcgaa accatgacaa ctataaaggc aaaacgatag
    20401 gctattggat gataggtatc caaagcacca tccctaaaat aatcaatggt cggtcttgat
    20461 accagaaata caaaaatggt taaatagaaa ataaaatgga ttaagtaata cttgatatca
    20521 ttccaacaag caattaagct actaaccaac aagaacaata aagtagaaag taagctaaca
    20581 ttattattat taaacagata cacaattcca cttactagcg tcaaggcata actgactatg
    20641 gtcaaactaa ataataatcg tttcccatca atcacttggt cacccccgtt ctaatgtaat
    20701 tttttagatt tttcaatatt tttcagtaat aagaatcgat ataaggaaat atttatgaat
    20761 agggccaaag cactaattct tctcccctta cggaaaattg gattcctaga aatagcaaag
    20821 gcatggcctt ttaaaaaacg atgaatctga gaataggctt caaactgttt atactgatca
    20881 tctagcaaca tcttatccag aataaagaag tgggcatagg ccaatctgaa aaaagcgacc
    20941 tctttcaagt caggatagtt tttcacaact tcattataaa acttttggta gatatcaata
    21001 taggctaaat ccttctctgc atagggtttg gtcgtaatac tatcccctct atggaaatag
    21061 taataatagg gtttagtatt aaccacatac tttttggcca acttgattaa atcaaaatgg
    21121 taataggcat cttcgtaaat caacccctta ggaaaggata gggcagttgc aatctgtctc
    21181 ttgattagct tattgcaaat cgtcccaggt attttttcac ctatgaggta ttcctttaga
    21241 aatgtttgag aatcacagac aaaatagtca tcctgattgg ctgactgtgg gctttcatca
    21301 ttagcataga cattcatgac accacagctt gaaacatccg catcttcttg aactaattgc
    21361 tcatataagc tctgaatcat ttctggatgg atataatcat ctgagtcaat aaaaatcaga
    21421 taatccccgt gagcctgctt catcccatca tttcgtgctt gcgacaatcc ttcgttcttt
    21481 ttatgaagca ctgacaccct gtcatcttgt tcagcgattg aatcacacaa gcgaccactt
    21541 tcatctgttg caccatcatc aacaagaata atttccagat tttgataggt ctgcttctga
    21601 atggaagcta tcgatttttc taggtactgc gccacattat agactggcac aatcacacta
    21661 attaatgcag tttccatgct actcctctaa tagtttttct acttgttcga tttgttttgt
    21721 aattgtaaat tgttgaatga attggctagc ctcatcgaca tcaaagtttg aggcagaagt
    21781 catgtaatta gtaatcgcct gagctgcctc ttgattgctc tcaatgattt gtccaaatcg
    21841 tccttcttgg gataattcct cagcccctcc aacgtccgta gagataaaag ggagtcccag
    21901 actcaaggcc tccacataca ctccaggaaa accttcttgt ttagacatag acaagagaac
    21961 tttcgtctga gatagatact gataaggatt tttttgataa ccaaggaaat gtacatagtc
    22021 ctcaatccca tactctttga ctcgtttttt cagttcctct tccatatcac cagccccgat
    22081 aaaatagaga tgatagtttt ttccctcttg gtgtaataat cgtatcactt ccactacacg
    22141 gtcagaaccc ttattttcct caatccgtcc gatagtacag atactttgag gagcaatctc
    22201 gatatcgatc ttctcttgag atttttctag aatagtctga aaatcatatc cattgtagat
    22261 tgtctgtaat ttagaagcat aatctggata aacttccttg atagaattgc tggtcttttt
    22321 tgaaatccct acaattgtat tcgcagcatc caactggctt ctatgtgatt ctcttttaga
    22381 gctatcctta agaagttctt caatacttcc atgaatccaa gatatcttct tgacttctct
    22441 tcttttagag aacaacagtg gtggattcat aatggtaaaa gaaacttcaa catcataatc
    22501 atcttttaca agcaaacgac gagtcagtct tggaaaataa attctcattc tccacaaaaa
    22561 agctcgtaac catctggttt ggcgataatc ttgaagggat tttaaaatgc gtacatgctt
    22621 tggaacagat tcatatccct tgtcaaagtg ctccatttca agaatatcaa tatcatactt
    22681 ttctggatcc agatttgaaa caatggttga tagaatcttc tctgcaccac ctccaagaga
    22741 aaaagaccac ataaaaaata agattttttt cttagccacc atattctccc ttgtattctg
    22801 tataagactt atccatatca gcgatgacag catcatgatg cggtacctgc ttgtctgctg
    22861 gtggaggcgt catataatcc ccaaaagcag ttctgagata gacatcatag ccgattggaa
    22921 taggcatctt tgttccttca aatggcaaga aaagattgtc ttcaaaagat gtgattgggt
    22981 acttgtttct catgtagcca ggacctgagc ataattctgt aatgccatca caatcagcca
    23041 aatcatactt agtcatttct ttctcagctt ttttccagat gcgataacgg agagattttg
    23101 gagccaaacc cagtaaaatg cgacttcccc atttcatgag agcaccatgc ttttctggaa
    23161 tagtttgcgc acaaaagagt gaataaatca aggcccaacg aacctgtttt ttccgctcag
    23221 ctggattttt cggataataa tccaaaggca aaacatccaa ggccagacca tgtggcaaat
    23281 ccaaatcctg ctgataaggc ttgatacagg tggtttcctt gtcacgaatg gtaataaaaa
    23341 gattacgatc aacaaaatcc ttgtgactct ttgacaagaa ataacgttca tctgcataac
    23401 gaggccataa ttctgctaat ttctcataat ctttacgagg cataaaaaag tctaggtcgt
    23461 cgtcccaagg aataaatccc ttgtttcgaa gggcaccaat agcgcctccg ccacagagat
    23521 aacagagcaa atcatgttct ttacaaaagg ccacaaaata ttcagccatc tccagactac
    23581 gagcctgaat tgcttttaaa tcagtcatat tgttcattat tctttctatc gtatcgtttc
    23641 attataccac aaacaagggg tgaaaatcta ttgcagactg taaaaaatca aagcctgact
    23701 gctatccaaa tagctatcaa actttgattt ttctgtctta tactcttcga aaatctcttc
    23761 aaaccacgtc agcttcacct tgccgtaggt ataggtaact gacttcgtca gtcttatcta
    23821 caacctcaaa actgtgtttt tagcagcctg cggctagctt cctagtttgc actttgattt
    23881 tcattgagta ttatcttatc tcaagcccat ttgagcgagc ttggtttgat atttgttttg
    23941 atcaaccagc aagcccaagc ctccataaac atcataggca tctacccagt cacccagttc
    24001 tggaatcgtt aatttttcaa taccattttt tgctccatcc aaaacagata aaccgtttgt
    24061 taggaggaaa gtataaggta cgttggttga ggtcatagca aaaacctttc caagagcttc
    24121 agaaccagtg aaaagtttag tgggatcttt aatttgctct aaaattgctg ttaaaacttg
    24181 ttgctgtctt tttgtacggc cgtaatccgc ctcatcatca tcacggaaac gagcataatt
    24241 gagcagggtc gagccattca tctgctgttt tccgacttta atggtttggg ttggagactc
    24301 agtctcggta gcatataaat catctccgac tgtagcttct gttaggggac gcccattcaa
    24361 tgttgaaaat tgagcatcaa tcgtcacccc atcagggaaa agcgtgtcaa tcgctgtggc
    24421 aaaggcctgg aaatcaacca aagcgtagta cttaatgtcc aagtcaaaat tatctttcaa
    24481 gacttgacga accatttctg cccctttttg cccctcttgt tctcctaact cgtaggctac
    24541 gtttaacttg ttatctgtct gttttctacc gttaatcact tgactataac catctatata
    24601 gaccaaatta tcacgcatga aactgactag cttcattttc ttatctgagc ccccgacatt
    24661 taataccata atagagtcag ttcgtgtctc aacactgttc tggccgattc gaccatcagt
    24721 acccatgatt aaaatattaa ctccatctct agtgtcctga ccattaaaga cttctacttg
    24781 agctgcccgg gcatcagcag ttttctttgc gctagcatct tggtaaccac gcaaaaacat
    24841 gaataccatg accaaagcca cacagaccaa aagtgaaaaa atcaccataa aaattcgttt
    24901 aagacggagc ttccgtcttt tcttttttgg agggaaagag agtgcttgtg atttggattg
    24961 tgagcgactc cggttcgcat agcttggtaa gtcaacctgc tcttctcttt cttgttccaa
    25021 gctggaacta ctatttcccc tagcaagagt tatcttttct tgcaaatagg caaactcatt
    25081 tttttctctc tcattgagat agtgaatatt ttttagtaaa taatcatagc gtaatttttc
    25141 atgatgactg agaggatttt ctttactcat cttctctcct ttccatggtc tgatattgga
    25201 taaatcggat aggcacccag aaccttatac tggattccga tggcttctaa ttctttttgg
    25261 gcaaagtgaa ccaagtcctt atcagtatag tccacatcga taatgaaaaa gtattctccc
    25321 agtgctgtct tgagtgggcg actttcaatt tttgtcaggt caattcctcg ccaagcaaag
    25381 gtcgacaggg ccttataaag tgcacctgga aggttgtcag gtagggtcaa ggctaaactc
    25441 attttttcag tttgtgattg caagggaata gttacacctt cagctcccaa aacccaaaaa
    25501 cgtgtgaaat tggcttccat ttcctgaata tcttcagcaa tcagttccaa tccatattct
    25561 tcagcagaac ttctaggtgc aattgctgca aagggctggt ctggatgttc tgaaataaag
    25621 cgggccgcat aagctgtact agctgttacc tcgatttgag cctctggata ctgttcatcg
    25681 ataaatttct ttccttgagc caaggcctgt ggatgtgaaa aaatcttttc aatcttagta
    25741 taacctggaa ccaccatcaa ctgctgatga ataggctgaa cgatttctgc tactgcttgg
    25801 atgcgagcct gatgaaaaag atagtccaag gtttcatgca cacttccctc gatagaattt
    25861 tcaactggca ccacagagta gtccaccaaa ccttgctcat aggccttgat gacatctgta
    25921 atgttggcaa aagcctgcaa ttcctcatga ggaaaagctg tctgcactac gtggtgtgaa
    25981 aatgatccct tagggcctag ataagcaatt ttcatctcag ttcctctata atttcctctg
    26041 ggcttagctt ggtcacatcc aaaacccgaa tggccacttc ctcataccaa gcctgtcttt
    26101 cttgaaaaat agctgctagt tcttccttac tattatttag aaaaagcggg cgctgattgt
    26161 ccttatcagc tgcgatacgt tggtagaggg tttcaaaatc agctttcagg tagatattat
    26221 ctgaatttgt tttgagtaag tcacgatttc tctgagaaat gattactccc ccaccagttg
    26281 acacgacttg gtctgtttgt aataaatcag ctaggacttc tgattctacc tgacgaaagg
    26341 ctgcttctcc cttttcagcg aaaaaattcg caatggacat acctaggcgc ttctcaatca
    26401 gagcatccat atcaaggtaa ttagggtcca agcctcttgc aatagtcgat tttccagccc
    26461 ccataaaccc taataacacc ttagccatga atcaagctct ccaaatcatc aaagaaacta
    26521 ggatagctgg tattgatggc ttctgcacgg tcaagctcca cctctccatc tgcaaccaat
    26581 agggctgcga tagctgtcat catgccgata cggtggtcac caaacgtatt gactctagca
    26641 ccgtgaagag ctgattttcc tttgataatc atcccatctg ccgtaggagt aatatctgct
    26701 cccatactat ttaaggcgtc tgccacaacc tgaatacggt ctgtttcctt gaccttgagc
    26761 tcctcagcat ccttgataac tgttacacct tgggcttgag tcgcaagcag ggcaataatg
    26821 ggcaattcat caatcaatcg tggaatcaaa gcgccaccaa tctctgttcc tttcaagtca
    26881 gaagactcaa caatcaaggt tgcagattta gcgactggat cgatttcagt tatttccaat
    26941 tttccaccca tggcacgaat gacatcaata ataccggtgc gagtttcgtt gatccccaca
    27001 ttctgcagca ctaaacgaga atttgggaca atcaaacctg cgactaacca aaaggctgca
    27061 ctggaaatat ctcctggtac gaccaccttt tgtccagtca gtttttgagg tccttgaact
    27121 gtgattttct tgccatccac acttaaatgg ccaccaaatt gttgcaacat atcttcagta
    27181 tgattacggg tgcactcttt ttcgataata actgactccc ccttagcttg taaggctgca
    27241 aacatcaagg ctgacttgac ttgggcagag gcaattggca actcataatg aataggtctt
    27301 aggtttttcg tcccttttaa gcgaagggga ggcaagtctc gttcagtttg ccctgaaatg
    27361 ctgacgccca tttttttcag tggaagggtc acacggtcca taggacgttt ggaaagacta
    27421 tcatctccaa acatctctac ttcgaaatct gcaccagcaa ggacacctga aatcaggcga
    27481 atcgaggtgc cagaatttcc catattaagg gcattttgcg gcgcttttaa gccagccatg
    27541 cctacacctt gaatggtaat aaccccatct ttatcctcaa tttcaacacc aaggtcacga
    27601 aaaacttgca tggtcgaaag aacgtcttca cctcgcagaa tatcataaac cttggtctca
    27661 ccctcagcca aacttccaaa gataatggaa cggtggctga tagacttgtc acctgggacg
    27721 cggatactac catgtaaatg gcgaatgttt gtttttagtt tcatactgga cctcatactt
    27781 gcaatacttt tacctatttt atcataaaaa gccagaaatt ccttaaaaat tcctgacttt
    27841 aggatagttc ttttcttatt tcagcaattc tgaaactggt tcaaaaacaa ttttttcaat
    27901 gtcagaaagg taaatggcca attgttgttg cttggtaaag aattctgaca agaggctatt
    27961 tccttgaatc tgtttaccaa agccttccat cttagcttgg aaggacgcat ctggcatttg
    28021 acctgtctgt gctagttttt gaatttcctc ttgaaaggca agataatctg taaatatttt
    28081 gcttgcctca gcatctgctg caatcgcatc tttagctgct ttaacagcct tgtattctgg
    28141 taatccgcgt agaccgcgac tgagttcgtt tgcactatcg taaatatttg acatgttctt
    28201 ctccttattt gatgacgact gtatagtcgg tattttctgt tatgagatac tcagctcttt
    28261 ccaagtcttg agcattttta aatgaaattt gtaggattcc gtgaatatcc tcacgatttt
    28321 cctcgttgat gtggatgtta accaaggaag ttccacgtag cagttccaaa atccgcagga
    28381 tgacatcttc ttcatcagga acgtcaacat agaggtcgta agagctatcc acaccaccac
    28441 gcttatggat ttccatggtc tggcgttgtt cacgcgcttg gttaaaaaag ttccaaattt
    28501 gctcttcatc tcccttacta atggcttgac caatcgcttc caaacgttcc ttgaaatcct
    28561 caattctatc cagaatgatc tcgctattgg acaagagaat ggaggtccac attcctggct
    28621 cgctttccgc aattcgggtc atatctcgaa aaccacctgc cgcaaagcgc cttgccatct
    28681 catgctcttg agcatagacc gcagtctgct ccatgagact agaagccaaa atatgaggaa
    28741 aatggctaat ctgagaagtg acacgatcat gctccttggc atcaatctcg ataaaacgag
    28801 catgaagacc tgaaagcaga tccttcattt ccttaagcgt gtcctgactt gtcaggcttg
    28861 aaggtgtaaa gatataatag gcattttcaa aaagattgac atctgccgaa gcagcccctg
    28921 tcttgtgact accagccatg ggatgggccc cgacaaagcg aacagacttg ccagccaaat
    28981 actgctccgc cgcatccaca atggttgact tggtcgaacc agcatctgaa ataataacgc
    29041 cttctcgcaa atccaaattg gccaactcct taatgaaagc aatagtttgt ttgattggca
    29101 agctgaggat aatgacatct gccaaaggag caaaactagc aaaatcatcc gttgcacggt
    29161 caatcatgcc ttctttcaag gcgatatctc tcgaagcttg actacgatta taacctaaaa
    29221 tttcataatc tggatgatcg cgtttgatac caagtgccat agaggctcca atcaacccaa
    29281 gacctgcgat atagattgtt tttgccatag gaactcctta atagttcttt gtatagtctc
    29341 ggtgtttggc taccgcttct tttagttcct caagattatc tgatgagaat ttttcgagga
    29401 tttcttgcgc cagaaccgtt gctacaactg cttccatgac cattcctgca gctggaagag
    29461 cagtcggatc acttctctcc acggttgcct tgtaaggttc gtgggtttcg atatccacac
    29521 tcataagagg tttataaaga gtaggaatgg gtttcatgac cccacgaaca acgatgggtt
    29581 gcccattagt cataccacct tcaaaaccac ctagattatt ggtacggcga gtataaccgt
    29641 cttctttaga ccagagaatt tcatccataa cttggctgcc tttacgataa ccagcctcaa
    29701 agccaagacc aaattccacc cctttaaagg cattgataga gacaacagct tgagccaatc
    29761 ttgcatccaa ttttctatcc cattggacat aggaaccaag accaactgga acgcctccga
    29821 cgactgtctc cacaacccca ccgatggtat caccatcacg tttgatttgg tcaatatagt
    29881 ccttgatttc ctgttctcgt tcttggttga caatagaaac ttcagactgg gcagctcttt
    29941 gcttaatttc agcgactgtc agattttcag gaacatctat ttctttgcca ccaaagacca
    30001 cgacatggtt ggcaatctcc atatccagct cagccaagag gcgtttggct actgcaccaa
    30061 ctgccacccg catggtggtt tcacgagctg atgaacgctc caaagaattt cgcaaatcat
    30121 caaaacggta cttaatcccc ccaaccaaat cggcatgacc tgggcgagga tgagtaattt
    30181 tccgcttgct tttaaggcgg tcttcaatgt cctccgcaga catgatgtcc agccatttct
    30241 ggtggtcctt attgatgaca tccatagtaa taggcgcccc tgtcgtcttc ccgtggcgaa
    30301 cgcccgaagt aaagacaacc tggtcactct caatcttcat acgaccacca cgaccgtagc
    30361 caccctgacg gcgtctaagg tcctcattga tatcctcagc tgtcaatgga agtccagctg
    30421 gaattccctc aataatagct gttagacggg ggccgtgtga ttctcctgca gttaaatatc
    30481 tcatacactc tccttatttt accaagtagt ctttcatctc ttccagagaa actgggtgaa
    30541 tggtcgccga accaagctct ggcaccaaga ccaatttcaa ggtgttacca cgcgctttct
    30601 tgtcatgagt aagagcctga taaagcttgt caacttccca attttcatag tcaacaggca
    30661 agccgaattt ctgacacatc tctgtgatag attgggtaat gccagctggc atgaggcctt
    30721 tttcctcagc aaccttggaa atctgtacca ttcccatggc aacagcctct ccatgcatga
    30781 ccttaccata accggcagtc gcttcgatgg catggccaat agtgtggcca aaattgaggt
    30841 aaagacgaat accattgtcc aactcatctt caaccaccat cttgcgcttc acctgacaag
    30901 aatgttcaat caaggtctct gcatgttcca aaatactctc aacagaacca ttcagtcccg
    30961 tcaagagagc ccacagttct ggatcctcaa tcaagccata tttgataact tcacccatcc
    31021 cttcaatcaa ctctcttttt ccgagggttt caagaacaag tggatcaatc aaaaccccat
    31081 ctggttgggc aaaggtcccc accatatttt tagcaaatgg tgtgttaacg cctgtctttc
    31141 caccgataga agaatcaacc tgagctgtca aactagtcgg aatctgaaca aagtgaatac
    31201 cccgcatata ggtagaggct acaaatccag ccaggtcccc aacaacgcca ccaccaagag
    31261 caacgattcc atcgctacga gtcagacctt gcttgactag aaattcatag actttctgaa
    31321 cagtagttaa attctttctt tcttcacctt ctaagaaatc aaaaacagct acctgaaaac
    31381 cagcatcttc taggctgagc ttgaccttct ctgcatagag agaggctaca tggttatctg
    31441 tcacaatgac taccttttgc ggttgccaga gttctcgcaa ccactgacca gcctgggcca
    31501 tacaaccttt ttcaatctga atatcataag gatgatgagg aatatcgatt ctgattttca
    31561 taggagagtc tccctttctt tattggtatt tttctgttaa agactgccaa atctcttctg
    31621 tcggcatttc cttgcctgtc catagttgaa aagcttctgc agcttgatag agcaacattc
    31681 ccagaccatt gactgctgga ttgccctgac ttctagccca tttcaaaaac ggtgtttcaa
    31741 agggttggta tatgatatct gcaactaaga gagtttctgg taagactatg ttttcaggaa
    31801 caggagagaa ttggccatcc atgcccacac tggtggcatt aactagcaaa tccgactcgg
    31861 caatccttgc ttgcagttca gaaacatatt ctaaagcaca caaatccact ttaaagcctg
    31921 tctgctcctg taacttgtct aggtaaggtc ttgttttttc catagaaacg gaacgaacaa
    31981 agaccgaaat ctgactgacg ccatccaaaa tagcctgtgc caagattgat ttagccgcac
    32041 cacctgcacc cagcagggtc atctttttac ctgaaattgt aaaagaaggc aagcacttaa
    32101 aaaatccctt gccatctgta ttatatccaa ttaaattgcc attctcattg acaaccgtat
    32161 taaccgcacc aatcaagcgc gcttcatcgc tcagctcatc caaataagga atcacctgct
    32221 ccttataggg catggacaga ttgatgccaa acatctggta gcgacgaata ttggccactg
    32281 tttctgccaa gtcactcgct tcaatctccc aagccacata agcaccgttg gtagctgtcg
    32341 cctcaaaggc tctattgtgg atgaagggag aaatagaatg cttaatagga ttggcaacaa
    32401 ctgcagttaa acgtgtatag ccatcaagct tcatccaaaa tctccctgat ttttttcatg
    32461 ctagctagag aaatctgccc aggggcacta acctcatcca gactggcaaa agaccaactc
    32521 gaaccagtca catccgcagt gatacgagag accttgccca ccttacccat agaaatggtc
    32581 acatattcct gttcaggatt gagggtttta aagcctcgtg tatagttcat caagtctaag
    32641 acatcctgct ccgtgtgagc catcaccgca accttaacaa gttttggatt taggatcgtc
    32701 aactctgaca agatttccat catgttctca ggtgtttctt ggaaattatg gtaactcaaa
    32761 acaagatttg ggaagtccag catttcctca aaaacatcct tgtagctata gtactcaaaa
    32821 tcaatatagt ctggttgata gagttgcgca acttccttga ttagatggat atactcttct
    32881 ggagaaaggt cgatttctcc accttcggag cgagttcgta gcgtgaaaac caactcacgg
    32941 cctgcgaatt tttcaaaaat ggctggagct acctgcaaaa tcgcttcttt aggcagatag
    33001 tcggcacgcc attcaatgat gtcggcatcc aggtacctcg tggcatccag agcctgagcc
    33061 tcctctaaac ttcttggcat tactgaaacg attaatttca tttactaacc ttcatactaa
    33121 tcaccttgag gtaattacta ctttcatctt ttttattata ggcaaaatct gctggaagac
    33181 catatttgtt taaaatctgg taacttcttc ctgcaaaacc tttatcaatt tgttctgtaa
    33241 atttctgacg ggaaacattg gcagcattag tactggcaat gataatccct cccggattta
    33301 aaatctcaaa actctgggaa atcaacttgt gataatcctt ggccacagag aaagtttgtt
    33361 ttttattccg agcaaagcta ggcggatcta ggacaatcac atcgtaggtc aagtttttgc
    33421 gtttggcata tttgaaatac tcaaagacat ccatgactat aaaacgatgc tcgtctgtgc
    33481 tgagcccatt tgcctgaaaa tgcgcttgag acaattctcg tgaacgtttg gctagatcaa
    33541 cagaagttgt ctggctagct cctcccatgg ccgcagctac tgaaaaagcc gctgtgtagg
    33601 aaaacatatt gagcaaggat ttacccatag ccaagccgtc aactaaacta ccgcgaacct
    33661 catgctggtc taggaaaatt cctgtcatca agccatcatt cataaagact tgatacagga
    33721 caccattttc taaaacagtg aaaaagtcag gtgcttcttg accataaaca tgggcagatt
    33781 catagtccaa acccttaaag cggattttct cataagctcc taaaacctca gggaaaacct
    33841 gtctaaaggc ttctgatata gtctgacgaa tctgataaac ataagagtta taccaagaaa
    33901 agacggcgta gtcgccataa aggtccactg tcagacctcc aaagccatct ccctcttgat
    33961 taaagagacg aaaggcagtt gtcaaatcat cttgatagta ggcgtttctc ttttctttgg
    34021 cttttctaaa caacgtttca aagaaagttt gattgaaggc caccttgtct ttgctgacaa
    34081 accagcccaa gcccttgttt tgctgagaaa ggtaggcagt cccaagaaag tttccttcct
    34141 gaccctgcac ctctacttcc tgatccttaa gattgacatt ctcaagatca ctggcttcta
    34201 gtaaaactag ccccttagca agcttctttt caaccctttt gctgactctt attctattca
    34261 taactaccat tatatcaaac ttttagacaa ttctcaaaaa agaaactacc cttgcttttt
    34321 tactcttctt ttaaaaaatg gtatactaga cttcctgcaa aactaggaag taaatgtgta
    34381 agaatcacaa taaaaaatgc tcttccgtct tggaggagca tttcttttta tcaacgaaaa
    34441 tcaaatagca aactatgaaa ctagcctcag gttaactgtg agattatagg tagagaggtt
    34501 gaatcagcaa tatgtgtctg tcaaatttag tgacaaaggt agtagaagaa agatgaagaa
    34561 ataaatctgc ttcaataggt atctggaaaa tttgatttta tagagaagcc ttttgttaca
    34621 aactcaatat actatcaata aataatatta tagaagcaac aataattata atttcaccta
    34681 tctgcatcat tctatttcga actctaaata tatgttctat caaaaatact tggatcacac
    34741 acattatagg aattaacgtt tttgaaattg aaaaatatcc caataaataa actataaaca
    34801 acaaaaatag aactatgtta tatttcttat tcaaaacatt cctccctata tatttttgat
    34861 taccaatctt aatcatttac aactacattc taacaaacta taaaagcgtt tgtcgaattg
    34921 aatttatcaa gcaagcgacc aaccagctca tcttttttct atttctgcca atatgcgtga
    34981 taggtaataa tgatagccaa aaatagcaag agcaagcagg aggataagag ctcctactcc
    35041 caagctgatg gcaaggatag gggagagaga ctgaaccaag aatatactcc caattacaag
    35101 ggccatcagg attgcactat aaataaacaa taaaactatg gcgactatgc catttgaacg
    35161 attcaccagg tccgtaatgc tactccaatt ggttgacaga tttttcacat ccttaaaata
    35221 atggtgacaa gaaaggatga cactggcaag gatccatgcc acaataaggt aaatcatcga
    35281 aatgatgggc aagcctagat atagagaaag accaagtaaa gtcagaattg gtaaaaagga
    35341 ctgaacagca aagataatcc aaaatttcac tttcacataa cgagcaaagt caaagggtaa
    35401 actcttcaga aaatcaacat tttccctctc caaggacaag gcaattgaag gcaggctggt
    35461 gatattgtta ttgacaactg ctataaagag agctataaaa aacaagggta accagtatgg
    35521 aggatgaatg tctggaacta tctgagaatc tcggattttg gaaatcagac cgatcatcat
    35581 gagataagga aggaaagcac ttgtaaaaag cactgtaacc acgccagtcc cctgtcccaa
    35641 gagggtgagg tggtagcgta aaaccatgcg gaaaaatccc tttttagttg ttgaaattct
    35701 ctccttgctg cgacgttctt ttttgacctt ctcctcacta ttaagcagga tcacgtcata
    35761 aaaacgagga aggaccttct ttttggtcag ataaagcagg aagagagtta gtcctatcca
    35821 agcgagcaga cccaatatgg cttctattga aaaaggctcc actgctattt tgtaaaagat
    35881 atgaagagga taaaggagaa atggaatgtc tctaactttg tcaacaatac ttccaaaagt
    35941 cgactgaaga aagaagataa atattaaagg tatgagaact cctatcccaa tcatcacatt
    36001 cgaaaaaata gactgatact ttctgaagac cctagtctga gccaagaaat gtactgccac
    36061 taccgtcact aaagtaacag agacaaataa taaggtcaag gacagtagca tcaaaggcaa
    36121 acccagccaa agagaaggag ctagactaat atagagggct agaaaataag ctaggattgg
    36181 tacaattcca gttagagctg gcaagaggac agacagtcct ttagcaatta taatctctga
    36241 ttctttaaaa gcatagggac tataggaggc caaatcctta ctctcataaa agacattgta
    36301 aaatgcagtt aaagaagttg aaaaggcaat cactagtaaa atagcaacca tgaaactaaa
    36361 ataaacaggc atttcctcaa aaggaaaatg aatggctata gtactaaaaa agatgagcat
    36421 caagagactg gaaaaaatgt aagaacttag gactctagcg gaaacattta ctttttttcc
    36481 agtattttta gcttgcttct ttcgtgggtt agccagatta gcttcttgag atgaatagag
    36541 gatattgata tcaactaatt ttttaatgac cttgagacgc atctgaaacc tcctcttttc
    36601 taccagcaag gctaaggtag atactttcca aagactggtc tgggttgtct tttctcaagt
    36661 cctctacctt accacaataa atcaaatgcc cctttttcaa aatagcaatc cgatcacaga
    36721 cttgctcagc tacctctagc acatgagttg aaaacaaaac tgtcttacct ttttgcgcat
    36781 gctccttcat catttgcttc aaatcaaagg cggcctgggg atccaaacca gtcaagggtt
    36841 cgtccaaaac ccaaatatca ggatcagaca agagtgcccc gatgacaaag actttctgac
    36901 gcattccgtg agaaagagtt tcaataacct gatagcgatt ttcagcaaaa tcaaaaacgt
    36961 tcaatagcct agctagacta gcctccaagt cagatctact cagatcatag gatgaggcga
    37021 tcaattccca aaattcattg gccgttaagc gtaaaaataa gtcaggcgag tctgctacgt
    37081 agccaatctt tcgtttaata gccaagcgat tttccgataa ctcctgaccg tctaccaaaa
    37141 tacgaccact gctgggtgaa atgatactga ctagggattt tatagtggtc gattttccag
    37201 ccccattatg accaatcaag cccataatct ctccattttc aatctgcaaa ttgagattac
    37261 tcaaggcctc tttatcacca tacaacttac taacattttg aaattcaatc atgggacaac
    37321 tcctatcttt atctgtatta tatatcgcta tactagcact ttgatacaaa aaaatcaata
    37381 ctttatttta agtagttaaa atagtttcct tctatcttac gcaaacgttt gctccgagag
    37441 atactttatg atagaataaa gaacaagatt gacaagtaag aggaaacatc atgcaaaatc
    37501 aaacactcat gcaatacttt gaatggtatc tgccccacga cggtcaacac tggacgcgtc
    37561 tggctgaaaa tgctccacac ctagctcatc tgggaatcag tcacgtctgg atgccaccag
    37621 ccttcaaggc aaccaacgaa aaagatgtcg gctatggggt ctatgactta tttgacttag
    37681 gagagttcaa ccaaaaaggg actgtccgca ccaagtatgg tttcaaagaa gactatcttc
    37741 aagccattca agcccttaaa gcgcagggaa ttcaacctat ggccgatgta gttctcaacc
    37801 acaaggctgc tgctgatcac agggaagcct ttcaggttat tgaagtggat cctgtagacc
    37861 gtacagttga acttggagaa cccttcacca tcaatggctg gactagtttt accttcgatg
    37921 gtcgccaaga tacctacaat gacttccact ggcactggta ccacttcaca ggtacagact
    37981 atgatgccaa acgccgtaaa tccgggattt acctaatcca aggagacaac aagggctggg
    38041 ctaacgagga attggtcgat aacgaaaacg gaaactacga ctacctcatg tatgccgacc
    38101 tagactttaa acatcctgaa gtcatccaaa acatctatga ctgggctgat tggttcatgg
    38161 aaacgactgg tgtagctggt ttccgtttgg atgccgttaa gcatattgac tctttcttta
    38221 tgcgcaattt catccgcgat atgaaggaaa aatacggtga cgatttctat gtttttggtg
    38281 aattttggaa tccagacaag gaagccaatc tggactatct cgaaaaaacg gaagaacact
    38341 ttgaccttgt cgatgttcgt ctccaccaga atctctttga agccagtcaa gctggcgcaa
    38401 actatgacct tcgtggcatt ttcacagata gcctgattga actcaagcct gacaaggctg
    38461 tgacttttgt cgacaaccac gatacccaac gaggacaagc ccttgagtct accgttgaag
    38521 aatggttcaa gccagcagcc tatgccctca ttttgttacg ccaagacggc cttccatgtg
    38581 tcttttacgg agactactat gggatttcag ggcagtatgc tcaacaagat ttcaaagaaa
    38641 tccttgaccg cctcctagcc atccgaaaag atttggccta tggagaacaa aatgactact
    38701 ttgaccatgc taactgtatc ggttgggtac gttcaggtgc tgaaaatcaa tccccaatcg
    38761 cagtccttat ctcaaatgac caagaaaaca gcaagtcaat gtttgtcggt caagaatgga
    38821 ctaatcaaac ctttgtagat ttacttggta accaccaagg tcaagttaca attgatgagg
    38881 aaggttatgg acaattccct gtctcagcta gatccgtaag tgtctgggca gtcaatacca
    38941 tctaatagct cataataacc aagctaggtc caagcggatt tggctttttt gtattcacaa
    39001 aaagacctac ccaaatggat agatctttac ttgattacaa tttacctgct actgcatcca
    39061 acaattcttg gatcttagct tggttgcttc ctcctgccat ggccatgtct ggtttaccac
    39121 caccacgtcc atcgatgatt ggtgctaatt ctttgacaag gtttcctgca tgaaggtctt
    39181 ttgtcttgct tgctacaagg acattgactt tgtcaccgat agcggcaact aggacaagaa
    39241 gatcagagta gtctttttgt ttccagttat ctgcaaaggt acgaagggca ccggcatcgg
    39301 atacagacac ttgactagca atgtaacgat gaccgttgac ttccttaaca tctttgaaga
    39361 tatcgcctgc ggctgcagct gcggcttttt ctttcaactc agcattttct ttttgaagtt
    39421 gacgaagttg ttcttgaagt ccttctacct tgtgaggtac ttccttgact tgaggtgctt
    39481 tcaaggttgc tgcgacagct ttaagagcat cctcttgttc acgataggct tcaaaggctt
    39541 ccttaccagt cactgccaag atacggcgag ttcctgaacc gattccttct tctttgacaa
    39601 ttttgaagag accaatctca gaagtgttgc caacatgagt accaccacaa agttcaatag
    39661 agtagtcacc aatagtcacg acacgaactt ctttaccgta tttctcacca aagagggcca
    39721 tagctcccat ttctttagca gtgtcaatat ccgtttcaac tgtcttaact tcaagagctt
    39781 cccagatttt ttcgttgact tgctgttcaa tcgcacgcaa ttcttcagcg gttactgctt
    39841 ggaagtgggt aaagtcaaag cgaaggaatt caacttcgtt aagagatcct gcctgtgttg
    39901 cgtggtttcc aaggatattg tgaagggcag cgtgaagcaa atgagtcgca gtgtggtttt
    39961 tcatgacacg gtgacggcga ttgctatcaa ttgccaaggt atattcttgg ttcaaggcaa
    40021 gcggtgcaag gacttcaact gtatgaaggg cttgaccatt tggggctttc tgaacattgg
    40081 tcacagtagc cacaacctta cctgactcat ccaagatttg tccgtagtca gctacctgtc
    40141 cacccatttc agcataaaat gacgtttccg caaagataag agaggcagtt ccttctgaaa
    40201 cagcttctac ttctgcattg tccgccacga tagctaccaa tttagaagac aattggctag
    40261 cattgtagtt gaagacactt tctacagtga tgttttgaag agtttcattt tgcataccca
    40321 ttgagccacc cttgacagct gacgcacgcg cgcgttcttg ctgttctttc atggctgctt
    40381 caaaaccttc acggtctaca gtcataccag cctcttcagc aatttcttca gtcaattcaa
    40441 ctgggaaccc ataagtatca tagagtttga agacatctga accagcgata acagattgac
    40501 ctttttcttt caagtctgct acaatgcctt gggcaaagtg ttgacctgag tgaagggtac
    40561 gggcaaatga ttcttcttcg ctcttaacga ttttctcaat aaagtcacgt ttctcaagca
    40621 cttctgggta gtagctttcc atgatttttc caacagttgg aaccaatttg taaaggaaag
    40681 gttcgttgat tcccaatttt tgaccatgca tagaagcacg acggagaaga cgacgaagaa
    40741 cataaccacg accttcattt cctggaaggg caccatcacc gatagcaaat gaaagagaac
    40801 gaatgtggtc tgcgataacc ttgaagctca tgttgtcgcc atcttggtca taaaccttac
    40861 cagacaattt ctcgacttca cggataatcg gcatgaagag gtccgtttca aagttggtct
    40921 tagccccttg gataacggcc accaaacgct ccaaaccagc gcccgtatca atgttcttat
    40981 gtggcaattc cttgtattcg ctacgaggaa cagcagggtc tgcgttaaat tgtgacaaaa
    41041 cgatgttcca gatttcaata taacggtcgt tttcaatatc ttctgcaagc aggcgaagac
    41101 cgatattttc tgggtcaaag gcttccccac ggtcaaagaa gatttctgta tctggtccag
    41161 aaggtcccgc accgatttcc cagaagttgt cctcaattgg aatcaagtga cttggatcca
    41221 ctcccacttc aatccagcgg ttgtaagaat ctttatcgtc tggatagtag gtcatgtaaa
    41281 gtttttcagc agggaaatca aaccattcag ggcttgtcaa aagctcataa gcccaagtga
    41341 tagcttcgtc acggaagtaa tccccgatag agaagttccc caacatttca aacatggtat
    41401 ggtgacgcgc agtcttccct acgttttcga tgtcgttggt acggatagcc ttttgggcat
    41461 tggtaatacg tggattttca gggataatgg tcccgtcaaa gtatttctta agggttgcta
    41521 ccccagagtt gatccacaaa agagttgggt catttacagg aaccaaactt actgatggtt
    41581 ctactgagtg acctttggtc gcccagaaat caagccacat ttggcgtact tgtgcactag
    41641 atagttgttt catattgtct ccttatttac ttgtttaatg tgattggctt tccagcattt
    41701 ccacatagtc aatcgcgaca cagagggaaa tgactaggtc tgcataagcg tcttcaagaa
    41761 ccgttacggt ataggtagag gtcagatgga agagttcctt cttaatttcc gcaatcaact
    41821 gatcgcgatc atccagcaat ttgaaattca aatcccagat attgccctcg atacgaagac
    41881 ctagattatc aaactcatac ttatctcgcc aaaaggtcaa cttcttacga atgacaaaac
    41941 tcgagccatc ccgaagctga atctcaaaac gaggaagcaa ggtcaagatt tctttactga
    42001 tctgactgac ttgttcacca gccgcatcat agatggtaaa agttttggga atcttaaaaa
    42061 atgatccctc cacctgatag gcaatttctc ccctgtcatc cttgatagcg aagcgttcgc
    42121 ctccaagacg aaacttttgt ttgacaagaa atattttcat caacacctcc aaaaatcaaa
    42181 agacaagctc atatcacgaa gggcgaaaaa ccgcggtacc accttcattc aatgaacttg
    42241 tcattctctt gttcttatgc aattgtatga ttgagtagca tgacttccta gcttagatgg
    42301 ctcgcagcac cgccatttct ctggactaag acaagtgaaa attaattctc aactttctta
    42361 ttataacgtt tttttaagct tgcgtcaact ggaaatgatc tccgttgaat tagaccaatt
    42421 ccctacatct ctgattactt tttcaggata tattttttct tactgccgtt tttcttttta
    42481 tcccaaattt tcatattact aaacacagct actagaatat ttccaaatat aaaggtgcct
    42541 atcacccaat atatggactc agttgttagg tattgtcgat ccaagccatc ctttagatgg
    42601 aatagtataa cagtttggtt aacaatcata aaggttggcc agaaactttt tttgaaaaaa
    42661 gtagacattt tcattatttg ttgccgcttt ctgtaaggtt aatactcaat aaaaatcaaa
    42721 aagcaaacta ggaagctagt ctcaagctgt acttgagtac ggcaaggcaa cgctgacatg
    42781 gtttgaagag tataggctta gtatactact aggcaagcaa ataagcaaat aagcaaataa
    42841 gcaaataaac aactagaata gaaaaagata gggctctaaa aactgacttc tattccttaa
    42901 aaacgaacca gcttgactga ttcgtcttct tacgtttatc tcctacttcc gatacatttt
    42961 aaactgtagg aagaggtcgc tatatttccc tgtccattta tggtcaaatt tctcataaac
    43021 ttctaggtgt ttcatggttt caacatcggg atagaaggcc ttatcttcct ttgtttcctc
    43081 tgggagcaat tccttcgctg gtaggtttgg tgttgaatag ccgacatact ccgcattttg
    43141 gagagcattt tcaggtttca acataaagtt gataaaggca taggctgagt tttggttttt
    43201 aactgttttg ggaatgacca tattgtcaaa ccaaagattg ctggcctctg tcggtaccac
    43261 ataacgtaga ttttcatttt tttctaacat ttggctggct tcaccagaga aggtcacgcc
    43321 gattgcaaca ttattctgaa tcatatagcc cttcatctcg tccgcaacga tagccttgat
    43381 atttggagtc agtttgtaga gcttatccac tgtctcttcc aactgctgca gatccttgga
    43441 gttgaggctg tagccgaggg aattgagccc cagacccagc acctcacgcg ccccatcaaa
    43501 gagcatgata gaattcttat actccggctt ccaaaggtca tcccaatgct caggcgcttc
    43561 atataccatg gtttcgttgt agacaattcc taaggttccc cagaagtaag ggatggagaa
    43621 tttattacct gagtcaaagg actggttgag aaactctggt ccgatatttt cgattccttc
    43681 aatttttgaa taatcaagcg gaaccaagag gtcttcgtcc ttcatcttgt taatcatgta
    43741 ttcacttgga atggcaatat cgtaggtcgt tccaccctgc tttatcttag tgtacatggc
    43801 ttcgttggag tcaaaagtct cgtactgaac ttgaattcct gtttcttctg taaactgagt
    43861 caagagttca ggatcgatat agtctcccca gttatagata accaattttt gactatctcg
    43921 actattgatt ttactatcta aatgagtcgc aattccccac aagacaagga taatcgctgc
    43981 aattcctgct aaaaatgaat agattttttt catgcttgct cctccttctc acgagagata
    44041 aagtaataac ctacaactag gataatacta aagagaaaga ctagagcaga cagggcattg
    44101 atttctaagg aaatcccttt ccgtgcacga gagtaaatct cgactgacag ggttgaaaag
    44161 ccatttcctg ttacaaagaa ggtcacggca aaatcatcca gcgaataggt gaaggccatg
    44221 aagtaacctg caatgataga cggagtcagg taaggaagca tgatttcctt aaacatctga
    44281 aattgactag ctcccaagtc ataggccgca tgaatcatgt cgccattcat ttccttgagt
    44341 cgaggcaaga ccatcaagac cacgatagga atggagaagg ccacgtgact agatagaacg
    44401 gtcaaaaagc caagtgaaaa cttgagttgg gtaaagagaa tcaagaagct agcaccaatc
    44461 ataacgtcag gcgcaaccat gaggatatta ttgagtgata gaaaggcttc ttggtatttc
    44521 ttacgagact ggtagatgta aatggcacca aaagtcccga taatggtcgc tatcaaggct
    44581 gataggaagg ccaagaaaaa ggtctgagtc acaattaaca taaggcgacc atcaccaaac
    44641 atggttttaa aatggctcaa gctaaagcct gtaaagctgt tcatgtcgtt tcctgcatta
    44701 aaggcgtagc caatcaagta aaaaatcggc aggtagagga caagaaagac cagtcccaga
    44761 taaaggtttg caaatttttt catcgttctc tcctttcctt ggtcacccac atggtgatga
    44821 acatggtcaa gatgagaatt acaccgatgg ttgaacccat accgtagttg tcattggtta
    44881 ggaaattctg ttcaatagcc gttcccagcg taataacacg gtttccacca atcaaacggg
    44941 tcagcatgaa gagactcaag ctggggataa agacagattg gaccccactt ctcactccgt
    45001 tcatagacag agggaagatg acatgacgga aagtctccca cttggtcgca cctaggtcat
    45061 agctggcatt gatgagattg ttatctatat cgtccaagac attgaaaatc ggcaaaatca
    45121 taaagggaag ctcgatgtag cttgcgacaa agataaagga gaaatcggta aaaagcaact
    45181 gctgtgaacc aattccgata aattccaaga attggttaat agagccattc tgaccaaaaa
    45241 tcccgataaa ggcataagcc ttaagaagaa ggttgatcca agttggcaga ataatcagca
    45301 taatccagag ttgacggtgt ttgagacggg tcaaaaagag ggccgtcgga taactgataa
    45361 gcagtgccac aaaggtcaca atgcctgcat aaagcactga gttgaaactc attttaagat
    45421 aggtcaagtt ttgtgacgca aagtaagatt tgtaattttc taaactgaac tggccttcga
    45481 tgttgaaaaa ggattgaccg aaaatcaaga ccaagggtgc caatacaaag agggcaatcc
    45541 aaagcatgta gggcactaca aagagtttag agcttgtttt cttcatctct ttcctcctcg
    45601 attgcattga tcaaacctgc ttcttgctct tcgatttcta cgtactcctc aatacgagca
    45661 tcgaactctt cttcggtttc attgagacgc atgatgtgga tgtcttctgg ttcaaagtcc
    45721 agaccgattt cctcacccac gatagcctta cgggttgagt ggatcatcca ttcatttcca
    45781 agttcgtcat aggcgataat ttcataatga actccacgga agagctgggt atcgacctta
    45841 acttggagct tgccttcttc aggaagggta atgcgcaagt cctctggacg aataacgacc
    45901 tcaacaggtt catttggctt catcccacca tcaaccgctt caaagcgttt gccgttaaat
    45961 tcgaccaagt agtcctcaat catggtacct ggcaagatgt ttgactcccc gataaaagtg
    46021 gcaacaaagt ggttgattgg ctcatcgtag atgtccacag gggttccaga ctggacaatc
    46081 tcgccatcat tcataacgaa aatccagtca ctcatggcaa gagcttcttc ctgatcgtga
    46141 gtgacaaaga caaaggtaat gcccaatcgt tgttgtaatt cacgcaattc gtactgcatg
    46201 tctgttctca atttcaagtc cagcgctgat aaaggctcgt ccaacaagac cacacggggt
    46261 tggttgatga tagcacgggc gatggccaca cgctgacgtt gtcctccaga aagtttgcgg
    46321 atggaacgtt tttcataacc ttccaactga accatcttga gaacttccgc tacacgctgc
    46381 tcaatttctt tcttatcaat tttacgcaag cgaagtggaa aggcaacatt ttcaaacaca
    46441 ttcatatgtg ggaacaaggc ataggattgg aagacggtat gtacgtcgcg cttgttggtt
    46501 ggaatatcat tgatacgaac accgtctagc atgatatctc ctgtcgtcgc atccagtaaa
    46561 cctgcaataa tgtttagaat agttgatttc cccgaaccag atgcacctag aagggtgtag
    46621 aatttccctt cttccaactc aaagttgatg tctttgagaa ccttggtgtt gctgtcttca
    46681 aaaactttag agacgttttt gaattcgata attggttttt tcaattggca taaattcctt
    46741 ctttttcata gattaaccga tcggggctct gtcaggtccc cactacctct tgcagggagt
    46801 aaaaccacct gcatacatct tcgctaccga taggctttca cccaagatcc ggacttctct
    46861 ttcaagcgta atacctgagt gttccttgac tttttcgata accgattgga tcaagtcctc
    46921 gtagtctttg gccgttccat ctgcgacatt gatcataaat cctgcatgct tttctgacac
    46981 ttctacgcca ccgatacgat agcctttcaa gccagcttct gaaattaact gacctgcaaa
    47041 atgcccgact ggacgcttaa agaccgagcc acaagatggg tattccaaag gttgcttgag
    47101 ttcacgtagg tgcgtcaagc ggtccatttc ctgcttgata acctgatggg ttcctggagc
    47161 tagggcaaat ttaactgaca agacaactgc accagactcc tgaatagctg aatggcggta
    47221 accaaaagcc aagtctttag cagacagggt ttcgatttct ccatccttgg tcaagacctt
    47281 acaagactgc aagatgtgag caatctcgcc accataggca cccgcattca taaagacagc
    47341 accgccaacg cttcctggaa taccacaagc aaactcaaag ccagttaaac tatgacggag
    47401 ggcaatgcga gttgtttcaa tcaagttagc cccagcttct gcttcaatgg tatagccatc
    47461 aacagaaacg ttattgagct tgtcacacaa gatgacaaat ccacgaatcc caccatcacg
    47521 aacgatgata ttgcttgcat tgccaagaac catccaaggg atattttctt ggttggcaaa
    47581 tttcacaacg cgagccaact caaaacgatt tcgtggaaag accaaataat cagcctctcc
    47641 acctactttt gtataactat agctatgcaa gggttcctta aaacggatat caattccttc
    47701 taagatttca agcatttttt ctcttacaga catgtcactc ttccttttac aaaattcatt
    47761 ccattatacc atttttagag acatttgacg accataaaaa taccttgttt ggattttgca
    47821 taagaaaaag aggttccccc ctttttatga ttttttacaa aagatttcct tggttccata
    47881 ggcgaccaga acgagctcca gtgctagaat cacttcaacc aagactggat ttgtcaacca
    47941 gcctacttgg aaaagagatg gtgccagatc aaagaaggca tgcaagccat aggctgctag
    48001 gagataaatc catttcttct ggcgaacagc ttggtaaacc caaactgtca aaagtaattg
    48061 gaaaccaagc gccaagattc gctcaaaacc aagcaaataa atctgccaga ccgaaagtga
    48121 ctgaatggtt tttaacatat tttcagacag taattgcata acctgtgctg tggattctga
    48181 gtttgaactg ccgaaagaac gatgtaaaga ttgagtaaac tagtaaggcc tagaaaaatc
    48241 aactccaagc caccatgccc taggccatag gccaaggcat ctgccttttc caaacttctc
    48301 tttttctcca accatttgaa gaaaacaaga cgagccgttt cctcaaaaaa tgctgccatg
    48361 gctaggccat agataatata gataagcgaa tgatcttgca agagggcaat actaccgtct
    48421 ttttgagggt gcaaaatcaa gatatgcacc agtttttcca aaatctgcga agagacaaag
    48481 aaagcgactg cacccaagcc caagacagct agattaatct ggtatttctt tttggcaaac
    48541 caaatgcttc ctatcagaaa agctagcaac agcaacatgg taataatgat atgaatggtc
    48601 attttcttct cctattctgc cttttcaata tcttttttca tctcgtcaac attgaactta
    48661 gcaaacaagt attgacggtc ttggactggg aaacgttggt ccaactggtc aactgctccc
    48721 acctcgataa tgccttcctt gatgacaaaa tccatgacat gtccaccgaa ggtcaaatca
    48781 tctgatatga agtgcagatg gtagcctgcc acactgaccc catggaaaat ctcaggcgtc
    48841 cagaaaccaa caatagtccc cgcaacattg tcacgactat attccggttg atgggttgcg
    48901 acatcagcaa acttggtatc gggtgttgac ttaggaatca tacgcacatg catatgtaaa
    48961 aattcccccc gaatcttgat agagcggaaa agattttccc catcataata agactcaatt
    49021 cgttctttca attccttgtc tgtcatctca aagcgctggc ggaaaatgac ctctgcctga
    49081 tgcggtacca ctgcagcgta aggaataagg gcatctggtg acacttccac aatttctggc
    49141 tggtctcctg accctttggc ctgataagcc ttgccatcca agacaatcaa ttccccatca
    49201 atggaatcca aggttcccaa accaaggtca ccatgttcta gcaattctcc tactgtcata
    49261 gtaccaccat aaaggccagc catcaaggct ccaagagtat tgtattgaaa taatttcact
    49321 ggttcctgca cgtttttatc cattcacttt cttgtctgtt attctataaa tcttactcct
    49381 aagtatacca catttgcccc tagatgtgaa cgagagaaac gctctagaca ttgccaagaa
    49441 ggaaaaaaaa gggtacaatg taacaaaatc aagggaggtc tggaatgaag aaacaaagca
    49501 agtacaaaga ggtcgtttcc tatctgaaaa atggtatcga gtctgaacga tttccgacgg
    49561 gtagtcgcct gccttctatc cgtcaactga gccttgactt tcactgcagc aaggacacca
    49621 ttcaacgagc cctgctggaa ttacggcacg aacaatacct ctatgccaag cctcagagtg
    49681 gctactatgt attagaacaa gggcaacatc aagacctaga aatcgaggtt accgacgaac
    49741 atgccagtgc ctatgacgat ttccgactct gtatcaatga aaccttgatt ggacgagaaa
    49801 actacctctt caactactat gacaatcaag aaggattaga agacctaaga cagtccattc
    49861 acaaactcct atttgagcaa gctctctact gcaaggctaa ccaactagta ctgacttctg
    49921 gaacccaaca agccttgttt atcctctctc aaatatcctt tcctagacaa gccaaggaaa
    49981 tcttggtgga acagccaacc taccatcgga tgaatcgcct cttgattgca caggggctgg
    50041 actatcaaac gattgaacga ggcattgatg ggattgactt ggaggagctg gaaggccact
    50101 tcaaaacagg aaaaattaaa tttttctaca ccattcctag atttcactat cctctgggac
    50161 attcctattc tgagcaagac aaacgatcta ttcttaactt agctgccaag tatgatgtct
    50221 atatcgtaga ggacgattat ctgggtgatt tggactccaa gaagggccaa accttccact
    50281 atcttgatac agaggagcat gtcatttata tcaagtcctt ctcgaccagc ctttttcctg
    50341 cccttcgtat tacagcactc attcttccaa atgctatcaa agaagcattt gtggcctaca
    50401 aaaatatcct agactacgac agcaacctca ttatgcaaaa ggccctgtca ctctatattg
    50461 acagtcaatt gtttgaaaaa aatcgtttgg ctcgcttgac caatcatgaa tcttaccaaa
    50521 aacaaatcga ggaaaggata actaaaacac cttgtcccct tcctcattat cccctacacg
    50581 atggtttatt gctagacctg agacagtatc ctaaaatcgc cagtctcaaa cacagtcaac
    50641 tgggcttgga cttctttgaa gaggcctatt taagcacctg tccttatcaa tttgccaagg
    50701 tgtccctaga caatctggaa aatgttttaa actatttaaa agcagaattg gaatgacatc
    50761 caactctgct ttttcttatt cttcaacttc agttagactt gctgctcttt caagatagct
    50821 ttggtaagtt ccttcatcct taagtttttg gatgaccttg tctaccactt ctttcaaatc
    50881 atcactattt tttctaagag caacggcatt ggcgtcgccg tccttcatct tcaagctgac
    50941 agttgcgaca gctaagccag cgtttttagc agcataacta agtgcaacag gctcatccat
    51001 atgaacagca tctatttttc cagcctgcaa ttcattgact gcttcaccca tattagttag
    51061 ggaagttaat tgaacttttg gcaattgttc cttgaccatt gattctggaa cagtcccttt
    51121 ttgggctgca atattagcac tttctaggtt agttaaatcc ttgtattttt ccacatcagc
    51181 cttacgaacc aagaaactaa tcttgttttc atagtatggg attgaaaaat caaagacttc
    51241 ttttctctcg tcagtagcac taattcctgc aactgctagg tcagccttac cagtttgaag
    51301 actggtcaaa acattatcaa aactcatgct tgagatttcc aacttaaccc caagttcatc
    51361 agcgatagcc tgagccatgt cgatgtctgc accgactacc tggttctttc catcaaccaa
    51421 tgattgaaat tcaaagggtg catagtcagg actggttgcc acaactaatt tccccttttg
    51481 cttaatggcc tcaacagctg actgagaacc attagaacct gactggcaag ctactaagaa
    51541 gaaacttgca agaaaattac ataaaacaaa tatccatttt tttgatttca taaataaaca
    51601 acctctctgt taattttgta taattataac gatatccaag ttacttgtca agtgtttttt
    51661 aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg agccatcagt tgatttcaag
    51721 ctccttttta tacagaatta aactatttta tagttcgaca atcttacctg tttcaaagta
    51781 gacaacccat tcacagatat ttttagcata gtcaccgata cgctccaagt aggaaataac
    51841 ttggaaataa tcacgacccg taacaatggc ttctggattt ttcttaatct cttcagtcgc
    51901 aaggtcacgg atagtttcaa aatagtggtt aatttgctca tccatggagg ccacccggta
    51961 tgcgtcgtca acagaaccat taagataaag atcaagtgct gcttcaacaa cgcttttaac
    52021 ttcacgtccc atttttttaa tttcttcctc tacagctgga atgcgctctt cccccttcat
    52081 acggatggtt gcctgagcaa tggctacagc gtgatccccc atacgctcca catctgatac
    52141 agccttaagg acagtcaaga ctgtacgcaa atcttgagag actggttgtt ggagtgcgat
    52201 catttcaaat gatttctttt ccagtttcac ttcgtattca tttacttctg catcatcttc
    52261 gatgacctct tttgccaggt cacggtcatg cgtgacaaaa gcacgtaccg tacgattgat
    52321 ttgtgagagc acttcttgtc ccatagcgta gaactggtta tgtaatttct ctaaatcttc
    52381 ttcaaattga gatcgtaaca tctttcatct ccttatccaa attttcctgt aatatagtct
    52441 tccgtttcct tgtgttgggg atcaaggaac atctgcttgg tatcattaaa ttcaatcaaa
    52501 tctccatcta ggaaaaatcc tgtcttatca gagatacgtg aagcttgctg catggaacgg
    52561 gttaccagaa gcatggtgta cttgtctttt agaccataca aggtttcctc aattttacca
    52621 gctgaaatcg gatccaaagc cgaagttggc tcatccaaga ggatgatttt aggactagtt
    52681 gccaagacac gggccacgca gacacgctgc tgttgaccac ctgacaatcc aatagctgaa
    52741 tcatatagac gatccttgac ctcatcccag atagaggcac cttgcaaggc tttttctacg
    52801 gcttcatcca gaacctgctt atccttaatt ccattgatac gaagcccgta gacaacattc
    52861 tcatagatag tcatagggaa aggattaggt tgttggaaaa ccattccgat ttccttacgt
    52921 aattcaaccg tatctgtacg cggactgtag atgttgtggc cattgtacac cacggatcca
    52981 gttgtggtca cctctggatt gagatctccc atgcggttga gagacttgag gagggttgac
    53041 ttccctgatc cagatggacc aatcaaggct gtaatttcct taggttggaa agatagggaa
    53101 acactattca aagccttctt tttattataa taaacggaca ggtctgatac ctgtaaaatc
    53161 gcatctgtca tacggtttcc tttctaacca aagtgaccag atacatagtc attggtggac
    53221 tgtagcttgg cattttggaa aatagttgca gtcttgtcat actcaatcaa atcacccaag
    53281 taaaagaagc ctgtgtagtc acttgcacga gcagcctgct gcatattatg cgttacaatg
    53341 atgatggtaa agtttttctt gagctcaaac atggtctctt ctagttgcat ggtcgcaatc
    53401 ggatccaagg ctgaggctgg ctcatccatt aagaggatat ctggcttaac agagatggca
    53461 cgagcgatac agagacgttg ttgctgacca cctgataagg tcaaggctga cttgtggaga
    53521 tcgtctttaa cctgatccca gagggcagcc tgacgaaggg aggtttctac gatttcatct
    53581 aggacttgct tatccttaac tccagcacgt tcatgcgcaa aggtaatatt acggtaaatt
    53641 gacttagcaa atggattggg gcgttgaaaa accattccaa tgtgtttacg catttcataa
    53701 acgttgattt ctggacggtt gacatcaatt ccacgataga gaatctgccc agttacttta
    53761 gcaatatcaa tggtatcatt catgcgattg agactgcgta agtaggtaga tttccccgat
    53821 cccgacggac caatcaaagc tgtaatttta tttctttcaa attgcatatc aatcccctta
    53881 atggattcat ttttaccata ataaacatgg acatccttag tagaaagggc tactttttct
    53941 tcaggaaagg taaggatatg cttctcatcc cagttatatg ttgacatggc ttctccttta
    54001 ggcagcggtt aatttcttgt gtagatagct tccgaactta cgagctccaa agttaaaaat
    54061 caggataaag atcaggagca cagcggcaga acctgctgat acaatggttc catctggaat
    54121 agtgccttca ctattgactt tccagatatg gacagccaag gtttctgctt gacggaagat
    54181 agagatgggg ctagtcacac tgaggatatt ccagttagac cagtcaagag ctggcgccga
    54241 ttgccctgct gtatagatca gagctgcagc ttcgccaaag atacgaccag atgccaagac
    54301 gacacccgtt acaatacctg gaagcgcttc tggaataaca acatgaacca ctgtctccca
    54361 gcgagaaatc ccaagagcca gaccagcctc acgttgggta tggtgaacgt gtttcaaact
    54421 atcttctaca ttacgcgtca tctgaggcaa gttaaagact gtcaaggcca aagcacctga
    54481 aatgattgaa aatccatact caaactggac tacaaagatc aagtaaccaa agagacccac
    54541 caccactgat ggtaaagagg acaagatttc aatacaagtc cgcacaaagt tggtaacagg
    54601 acctttttta gcatactcag ccaagtaaat cccagctccc atagaaagag gtacagaaat
    54661 aatcaaggta atgaccaata ggaaaaagga attgtaaagc tgaatgccaa tcccaccacc
    54721 tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccag gagatatggg gcaagccccg
    54781 aaccaagata tagagaatca aggaagccaa gattgtcaca atgatgctag caatcgtata
    54841 gaggacagct gttgcaagtt tatctaattt cttagcgcgc ataatttttc tttcctcttt
    54901 ctttcgtaat caatttaatc acactgttaa aaactaaact catcaagagc agtaccaagg
    54961 ccagtgacca gagaacatta ttatttacag ttcccatgac agtgttccca attcccatag
    55021 ttaatataga agttaaagtt gcagctggtg tggtcaagga agttgggata acagctgagt
    55081 ttccgacaac catctggata gctaaagcct caccaaaggc acgcgccatc ccaaagacca
    55141 ctgcagtaaa aataccagaa cgggccgcct tcaagatcac acgccagata gtctgccagc
    55201 gagtggctcc catagcgaaa ctggcctcac gataataacg aggaaccgca cgcaagctat
    55261 ccgttgtcat aaaggttacg gtcggtaaaa tcatgacaaa gaggacggaa atccctgaca
    55321 aaatcccaaa accagtccca ccaaagacac tgcgaacaaa gggaacgacg acttgcaagc
    55381 caataaatcc gtacactact gaaggaatcc caaccaggag ttcaatagct ggttgcaaaa
    55441 tcttcgcccc ttttggtgat acttcggtca taaaaactgc tgcaccaata gcaaagggtg
    55501 ttgcgataag ggctgagaga atggtaacga taaaggaacc caaaatcata ggaagggcac
    55561 caaattcttt actagaagga ttccaagttc ctcccaaaag aaagtcaaag atattcacac
    55621 cattgacaaa gaaggtcgac aagccttttt gcgctacgaa aaccaaaatc atagccacaa
    55681 ggatgactat caaagaaaga caggcaaagg tcaaaccttt tcctaatttc tccagacgag
    55741 aattctttga tggaagcaac attttcttag ctaattcttc ttgattcatt attgtctccc
    55801 ttccaacact gtcacagttc cggcagcatc tttttcaacc ttcatttcct taatcggaat
    55861 atacttcaat cctttgacaa tcccttcttg ggtctcatcc gagagaacaa aattgagaaa
    55921 ttctgcagcc aactcattgg gctgccccaa tgtatacata tgctcataag accacaaggg
    55981 ccaattattg ctacttatat tttctggact taagtcatag ccattcaact tcatgctttt
    56041 gaccgaatca tctatatagg taagagataa ataagagata gctcctggac tttttgatac
    56101 gattgatttt accgctccat ttgaatcctg ctcctgactt tgcatggcag actgaccttc
    56161 cataatgaca gtatcaaagg tagcacgaga gccagagcca gctgcccgat tgataacaga
    56221 gatgggtaag tccttaccac caacctcttt ccaattggtt acctcaccta tgaagatttg
    56281 acgaagttgc tctgtcgtta ggttatcaac atcgacctcc ttattggcaa tcagagccaa
    56341 gccagctacc gcgaccttgt gatcaacaag agcagaagca tcaattccgt ctttttcttc
    56401 agcaaataca tctgagtttc ctatatcaac tgccccagac tgaacctggg acaagcctgt
    56461 accagaacct cccccttgga cattgaccgt ttttccaaca tggatcgtgc caaattcatc
    56521 tgccgctact tcaaccaagg gttgcaaggc agttgagcca acagccgtta tggattctcc
    56581 acgatcaatc cagctagcac agcctactaa acaagccgtc agccaaaaag cgataagaga
    56641 cagagcaagc ttttttcttt ttttcactgt ttttctcctc gaaaataatt atgaatactg
    56701 tgaatttttt aagtagttct ttatgagttg acgcatgaat tcttaccaaa tttctgcgca
    56761 attgattatt tatataatat aggctatatt actctttcct aacctccttt tttcatatgt
    56821 ggataaaatc tcttgtctat cccttccccc attgtcaccc attatagtca tttcgtgtct
    56881 ctttttcccc tttttaatgc aagggaaatt actcttctta gatgataatc caaaagctag
    56941 aaaggtatct caaacctctc tactctccca gactagttta caactaaaag gaaaagattc
    57001 tattttatga gaaatctagt ttacaagcgg taagaacgct aataactaaa cttcttgtac
    57061 tctttgaaaa tctcttcaaa gcagtgtttt gagctatcta tggctagctt cctagtttgc
    57121 tctttgattt tcatcgagta gtaaaactac atgtgatggc aatcaagata tcaagaatca
    57181 tcctactaaa aaaatccata ctttcactat aacatagaat aagatatttg actagcattt
    57241 tcatttgaat ctgaggcctt ttggaaaata atttttcaaa acatttccag taacctttgc
    57301 aaagcccaag ccattgcctt taaccaaaac ttggtaccaa ccatttggca gactttctgc
    57361 cagctgaacg gtttctccag tcgcatactt gacaaactct tcttggccaa tttcaaccga
    57421 ctgttcgacc tgactcggtt tcaaggctaa accaagagcg aaactgggct caaagcgttt
    57481 cttcttaaaa gtacccagat gcagtccatt gcgagcaatc ttgagcttcc ctaaatctgg
    57541 caaaagttct ggcaagagat aaagctggtc tccaaaagtc tgcaagatac ccggtagatt
    57601 gaccttcaaa tggttttggg caaattcctg ccacaaggca acttgttcac ggctgaggtt
    57661 actcttactt gccttaaatt taggagctgg attgttaccc ttaaactgta gatgggcaac
    57721 aaactgaccc tctcccttaa actgatgagg atacatccga gccgtttctg gcaggtcaat
    57781 accagctacc attccattga tatgctctac tggcaacaag tcaaaatcat actcttccag
    57841 caaccaattg acaatctctt cgttttcctc gggtgcccag gtacaggtcg aataaaccag
    57901 atgaccacct tcagctaaca tggtcactgc atcctccaga atttctcttt gcaagctagc
    57961 acattgactc ggataatcta agctccaata gtccatagca tcaggttgct tacgaaacat
    58021 tccttcacca gagcaagggg catcaagaac gattaagtca aaatagcctt taaagacctt
    58081 gaccaagcgg tcggcagatt cattggtcac cacgacattt gtcgctccaa aacgctccat
    58141 gttttcaacc aaaatcttag cccgtttgct tgaaatttca ttggaaacaa gtagcccctc
    58201 ccctgctaga taggctgcca gttgagttga tttgcccccc ggtgcagcag ccaagtccaa
    58261 gaccttcata ccaggactgg gttgggctac ttgagccacc atttgagcag caggttcttg
    58321 cgaataaact aaacctgtag catgctcagg cgatttccct gaaaccttcc catagtggcc
    58381 ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc tcttctttta agggattgac
    58441 ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga aaatctcttg cctcatctcc
    58501 tagtatctct ttatattttt caacaaatcc ttctggaaat tgcatttaag ttcttttcct
    58561 ttcgtaaata taggactgaa tttcctcctg catctcaaga ggcaccatca tgaccggctg
    58621 tctggtttga aaatcaggag cttcaccaaa aagggtcaca acccgatagc ccagactttc
    58681 ccctaaaata ctagctgcgg cataatccca tggttgcaga taagtgagat aggtcaacaa
    58741 acgccctgac aaaatcttgg caaaactaat ggccgcactt ccatagacac gaacaccaag
    58801 aaccgatcgg ctcaaatcag ccagccccca ttcattggtt tccagcatac cactattccc
    58861 tgcaatgaga aaatctccaa gtggtttagt tttaaaagga gctagggacc tatcatttag
    58921 acaaactgga aattccccac caccgtggta acaatcccct ttgaccacat cataaatcag
    58981 accaaactgt ccctgaccat tttcaaaata agccatcata acagcaaaat cttcctgctg
    59041 ggctacaaaa ttattggtac catcaatggg atcaatgacc caaaccttgc cctcttgaac
    59101 cgaggctcgc agacaacctt cttcagcaca aatcttatcc tcaggataac gggacaaaat
    59161 ctcaccaacc aagagttcct gaacttcttt gtccagtctg gtcaccaaat ctgttggaga
    59221 ggacttggtt tcaacacgca agtcttcctg catatggtca agaatgtact gacctgcttt
    59281 cttaacaagc tctttagcaa attcaaattt actttccaag agaaatcttt ccttcccctt
    59341 tttctttggc agcctgaact gctcggtaaa gtgaatagcc actaaccgtt tcaaattctc
    59401 gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc tttgaatccc ttataggagt
    59461 ccagtaactt tttagcctct actttgcctt cataggcagc ttcaacatca ttaaaaaaag
    59521 aaagcactga agcaagttct tcagtgctcc acgacaaatc tagtgggtaa ctatactgtt
    59581 tgttcattaa ctaataccag ctctcattct tgcttctttt agttcttgct tacgataact
    59641 acgagggaga aaagcacgaa tctcatcttc attaaaaccg atttgcatac gcttggcatc
    59701 aataataatt ggacgacgca aaagactagg atactgctca atcaaatgaa gcaattccga
    59761 taccgaaata ctctctacat caatattcaa tttttgaaaa atttttgaac gagttgaaat
    59821 gatgtcatca gtaccatttt cggtcaagga aaggatgtgt tgcaattctt ttcttgttaa
    59881 aggactggtc ataatattgt gttccacaaa gggaacctta tgtttttcta accaggcctt
    59941 agccttacga catgatgtac agctcggtga tagaaatagt gtaatcatgc ttttctcttc
    60001 ttatctatac tttgctactt ctattataca aaaaaataaa gcgcttgact agggattttt
    60061 agaaaaaaag cctatttttt caagaaaaat aggctgtttg cgaacgattg acacaattgg
    60121 atttggttaa ttcactctta acgatggttt taaacgatat atatttttat atatgcaaat
    60181 taaaaacatc tttcatttca cttcctacga cttttcagac acagatagcc aaagaagctt
    60241 tcatagaggg caaaaaagag gaggaaggca tgaagaaaga aggtctctgg caaaatcata
    60301 ataacaggat ccttggctgg atcaaaaagc caggtatcat ctcccacaaa gagaatttga
    60361 tggaaaagag taaagaattg gtcaaaacca atcaaaactc ccccaagtcc aatcatcaca
    60421 ggtaagacta ctagagtcag gagacttttt cgataaagag acaaaaagtc ctttttcaca
    60481 atcctattga caaagacata gaaacttggc agtgtcacta gagctactag ctgagccaaa
    60541 tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag ctgctgacga acgaaaatca
    60601 ggcatctgta agacctgact aaaaggattg gtcagataat tcattaagat atgaaaattg
    60661 tattgaatgg tttctggttt tagatagact cgatttgtta agtttagcca ctgaatctcc
    60721 ataggataga aaatccaagc cagataaatg gtcagaagga ttgagaggga gaggagaaag
    60781 agcatagagc cccaaaaggt caatttagtt ttcatcaaaa tcccactccg caaggctaga
    60841 aaccacatgt gtcggtgcga ttggcaggcc agctacttct tctgccttag taaaacctgt
    60901 cgtcaccaag agcgttggaa tgccattgtc aatcccagcc cggatatcag tcaaataatt
    60961 gtccccaacc atgattaact cttcacgttc caaacctaag tgctcaaccg ccttgtccat
    61021 aatgatggca ttgggttttc cgatataaac cggcttcact cgtgtcgcta cttcaagcag
    61081 cgtaatcagt gagccagcac ctggcaaaag accacgttcc gtcgggatgt tgaggtcagg
    61141 attggttccg ataaaatggg cacccttttg aatagcaaga gttgctgtgg caaatttttc
    61201 atagtcgact tgccaatcca gaccaactac cacgtaggca ggtttttcct tgtcttccac
    61261 ataaccagcc gccttgatgg cttccttgag tcctgcttct ccgacgacat agacggtctt
    61321 ttcaagcccc aaatcattca tatagtcgat ggttgccaaa gtcgctgtgt agacagtcga
    61381 taggggcgta tcgatattaa aattctgagc caacatctcc ttaacactct ctggagtgcg
    61441 ggttgtattg ttggttacaa agagataggg aatgtcccgc ttttgcaatt catgaacaaa
    61501 agtctctcca gcagggattc ggtctttccc cttataaatg gttccatcta aatcaattaa
    61561 atagccttta tatttcatct atttctctct aagccttttt tatttcttgc caagtaatga
    61621 ttgcttgggc attgataacc ccatcacttg taatttcatg cttgctttcc agtccagtcc
    61681 gttcaacagc cgatgtaatc accccacctg gtcgaacttc cttgacatac ttgaggttga
    61741 ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat gacctcaaaa atccagtcca
    61801 agtatttact gttattgaca tgaccattca tatccaagtc gtaaaaacga acatggtaat
    61861 ccttgctgat cggctcttcc aaggactcat acttcggtcc acggataagt tttttatcaa
    61921 aatcagactg gtaaggagcc acaatctcag gttcaacagc atggactttt cgactgtcgc
    61981 ggtccatgag aacaaaggtc gccatcatat ggatgagctc ctgccccgct tcattataaa
    62041 tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa ggcttccgtt tcgatggtaa
    62101 tttcttccgc aaaacgaggc aaacgaacca cctcaatatc atattctgcg ataatccaga
    62161 ccagattata gtcttccaaa atggccttat cactaactcc cagttcaatc gactgcatcc
    62221 ctgaaacttg cagtgacagc aaaatcacat ctggaagttt gatatgaccg ttcatatcag
    62281 ccatatcaaa aggaattttc attttcattt gataagttaa gcccatgatc ctactccaaa
    62341 ataaatcgtt ctgctacagt atctcccaaa aagagacctc tctttgtcat gcgaacgtgg
    62401 tcaccctcaa tctgcatgag gccttgttga accaaatctc tgacaatttc tccataaagt
    62461 ccagcaaaag actgtccaaa tttttcctca aatcgcgcca tggaaacccc ggatttcttg
    62521 cggagtccca agaacatttc ttcttccatt tgctcctttt gactcaggtg atcttctgta
    62581 atacaagcat tgccttcctc aaccgcactg agataatgac gaatgggacc atgattttta
    62641 tagcgtactc cattgacata accagatgcc cctgcaccaa taccatagta ttcagcattg
    62701 tcccagtaca tgagattatg acgactttca aagccgggtt tggagaaatt agaaatctca
    62761 taatgctcaa aacccgctcg ctccagctct gcaatgatgt actcaaacat ctccgcttct
    62821 agttcctcct taggcagagg caatttccca cgtcgcatcc ggttcataaa gaccgtatgg
    62881 ttttctaaaa tcaaactata caaactcatg tggggaatat ccagtccaat ggctttagcc
    62941 acattttcct ttacttgctc catggtctga ccaggcagag cataaatcaa atcaatggag
    63001 atgttgtcaa aaccagccag tttcaggcga tcgatatttt cataaatatc cttctccaaa
    63061 tgactgcgcc caatcttttt caacatctta tcatcaaagg tctggacacc tagcgaaaca
    63121 cgattgacag ccgaattttt caaaacagct atcttatccg catccaaatc gcctggattg
    63181 gcttcaatgg tcaactcttc caagacatac aagtccaagt ttttagtcaa gccattcagt
    63241 aaaacctcca gttgcggagc cgacagggct gtcggtgttc caccaccgat ataaagggtt
    63301 gacaactttt caatatcata agaacgaaac tcttccagca gatgctctaa atagctgtcg
    63361 actggctgat ttttgatgaa gacctttgaa aaatcacaat aataacaaat ctgggtacaa
    63421 aatgggatgt gcacataggc tgacgttggt tttttctgca tagtaattat tataccacaa
    63481 agactagatt ccagataaaa atcaccatcc ccagatacat agtccgtccg gagatggtga
    63541 tggtttattc ttctgttata tcaatcacaa tctcttctga gtcatcaaga gcttcggctt
    63601 tttcttgcca ttgctccttg aaattattta attgattttt tgatgcttct gtcgcttgaa
    63661 gagcatagga tttagcttga gcaagtatac tgtccacagt gatttcacct gactcaacct
    63721 gttcttttgt tttcagaaca aaatctgtag cctgctcctt aacttctgtc agtttttcac
    63781 agacttgctc cttggcatac tccggatctt ctctcaaatc atctagaaaa tcttgagcct
    63841 gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa ggcaagagct gcacctgaaa
    63901 cggttcctaa aaggattgag gataatttac ccataaggat tctccttttt tattttttga
    63961 aaaatttact tgcaagacga agagctgaca gacttgcacc agtcttgagt gtttttgaac
    64021 cagctgatga agctttcttg ctcaagacac gcgcatggtc attgaggtct gaaacagata
    64081 gagataaatc tgcaacagca ctgaagagtg gatcaatcgt agccaccttg acattgatat
    64141 catctgccaa gacattgacc ttagccaaca actcattggt gtgatgcaag gtcacatcca
    64201 catctgaagt caaggtttta atcgtctttt ctgtttcatc gatgacacga ccaagctttt
    64261 gtacagtaat gatcagatag accaaaaaga caatcaaagc tagggcaaca agaatatatg
    64321 caacttctaa catttagttt tcctcctctg taatatagta aggggccttc tttcgatttt
    64381 gataaataac gatcattata ccgagaccga taaggacaac tgacagccat tgggacactc
    64441 gaaagccgaa gaacatgaga ctatctgttc gcataccttc gataaccata cgaccgaaac
    64501 cataccaaat caagtaaaag gccgtgatat gacctcgtct gagactcttc catttccgtc
    64561 taaaaatcag aatcaaggca aagccaagca gattccatag agactcataa aggaaagtcg
    64621 gttgacggta gctcccctca atatacatct ggtcacggat aaagccaggt agataatcca
    64681 gattatccac tgttgcacca taagcttctt ggttaaagaa attaccccaa cgccccaaac
    64741 tttgagcaat cataacgcta ggcgccgcaa tatctagaaa atcccaagta ttgatgagtt
    64801 tacggtcagc aaagatatag agcacaagag ccccagttat caaaccaccg taaatggcca
    64861 aaccaccatt ccaaatggca aaaatctctc ctaaattctg actatagtaa tcaaatcgga
    64921 aaataacata gtagagacga gctcctaaaa tagccaaggg aaaggctact aagataaaat
    64981 ctaaaatatc gtctggtatg atcttctttc taggtgcttc tttcatggtc aaataaaccg
    65041 caagaatcaa gcctgtcaca atacataagg cataccaacg aatggctagg ggtcctagtt
    65101 gaatagcaat tggatcaagc attttgcacc tcatttcgag cgattagact tgtcagtcgt
    65161 tcgtcgaaca aacgggtcgc atcaaagccc atttccttgg cacgataatt catggcagct
    65221 gcctcaatca caacagagat attacgacct gttttaactg gaatacgaat acgaggaata
    65281 gctacgccag aaacttcaag ttcctctgca ttgtttccaa ggcgatcaaa ggtcttatgc
    65341 gtatcgtaat tttccaaata gacagcaagc tgaacctgtg aagaatcctt gacagcactc
    65401 gcaccgtaga gactcataac atcgataata ccaaccccac gaatttcaat caagtgtttc
    65461 aaaatttcag ctggttcacc ccagagagta atctcatcct tggcaaagat atcgacacgg
    65521 tcatcggcta ccaaacggtg accacgtttg acaagctcaa gacctgtctc gctcttacca
    65581 attccactat ctccctgaat caaaacgccc atcccataaa tatccatcaa gacaccgtgc
    65641 acactggtac gttctgccaa acgagaatcc agatagctag ataactctcc agataaacga
    65701 ctggtagctg cacggctggt taaaatagca atcttacatt ctctagcagc ctttaacatc
    65761 tcctctggaa ccaccaaacc acgggcaaca atgactgctg gtgtctcagg tagaaacatt
    65821 tttttcaaaa cttcataacg gctgttggaa ggcatgctga tcagataaga ccactccttc
    65881 atccccaaaa gttgaatccg ctctggtgta tagtagtcaa aatagcctgt catttcaaga
    65941 ccaggtcgcg taatatccgc tgtattgatt tccttttcaa gcaattctgg ttcaccatag
    66001 acaatatcta gtctaagctt ttcaatcact tcttttacta aaaccgacat catttcctcc
    66061 ttcaaatgaa ttcttctctc tattatatca aattgtagga ggaagtttca gatttttgca
    66121 ggctttggag tatttattta aaagaaaaag gactagattt ctctagcctt tcatttcaat
    66181 tagaattttt tacgtttacg agctacttct gatttacgtt tacgttttac agaaggtttt
    66241 tcatagaatt cacgtttgcg tgtttcttga agagtaccag ctttagtaac cgcacgtttg
    66301 aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta ctactgtttt agacattttt
    66361 ttcactccct tcaagttcaa tatctatttc attctacacg taaaaggaat aattgtcaag
    66421 caaaaatgcg gtttaatttt gattttttct tccatttata caagagttga aagcgttcaa
    66481 tagaacattg cttttttatt tttcgagtaa gctaagcgct tcagcatctg cgatgatggt
    66541 tacatcaggg tgattttgga ggctacttgc aggtaagttc tcagtcactg ggccagatac
    66601 tgttccggca atggcttctg ctttcgactc accgtaagca aaaagaataa tagacttggc
    66661 atccaaaatg tttttaatcc ccattgaaat agcttgggtt gggacgtctt caatcttggc
    66721 aaagaagcga gcattggctt cgatagtaga ctggtcaagt tctactagat gcgtttgact
    66781 gtcaaatgga gtaccaggct cattaaagcc gatatgccca ttgcgaccga ttcccaagat
    66841 ttggaggtca actggatggt cagccaaaat ttggttgtag cgttcaactt cagcttcagc
    66901 attgtcctta acaccacgag gcaagaaact ttctttaaat ggtttttggt tgaacaagtt
    66961 ttcttgcatg aagtaacgat aaaactgtgg attgtcccca tcaaggccca catactcatc
    67021 aaggttgaca ctggttagat ttgaaaaatc aaggtcactc tcaacaattt ccttgtaaaa
    67081 ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga gctccattag ccaatttttc
    67141 cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg ttttcaactt taataacttt
    67201 catcttttca tcctccattt ctgtctatat ttattatatg gtatagacca atttttgtca
    67261 agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac ttgaaacgtg ttataatgga
    67321 taggattaga acttagaaag aatgaacaaa tatatgaata cagctgattt tgatttccac
    67381 ttgccagagg aattgattgc ccaaacgccc cttgaaaaac gtgatgcctc caaactcctc
    67441 atcgtcaacc gtgagacagg agaaatgcaa gataaacact tccactctat tattgatatg
    67501 ctggaacctg gtgatgccct tgtcatgaac gacacccgag ttctccctgc ccgcctctat
    67561 ggtcaaaaag tggagacagg aagtcatgtg gaacttctcc tccttaagaa cactagtgga
    67621 gacgagtggg aagttctggc taaacctgcc aaacgcctca aggtcggtac tcgtatcagc
    67681 tttggtgatg gccgcctcag cgctgtcgtt acagaagaat tgacccacgg gggacgcatt
    67741 gtccgctttg aataccaagg aattttccta gaagtcttgg aaagtctggg agaaatgcct
    67801 ctgccacctt atatccacga aaaattagat gaccgtgaac gttatcaaac cgtctacgcc
    67861 aaggaaagcg gctctgctgc agcaccgact gctggtcttc acttcaccaa agaactgctg
    67921 gcagaaatcc aagctaaggg tgttcatcta gtctatctga ctctccatgt cggactcgga
    67981 acctttagac ctgtttctgt ggataatctg gacgaacacg aaatgcattc agagttctat
    68041 caactttctg aggaagctgc tgccaccctt cgctctgtca aagaaaatgg tggtcgcgtc
    68101 atcgctgtcg gaaccacttc tatccgcacc ttggaaacta ttggttccaa gttttatggg
    68161 caaatccaag cagattctgg ttggaccaat atctttatca aacctgggta tgagtggaag
    68221 gtcgtggatg ccttctcaac caacttccat ctgccaaaat caactctggt catgttggtt
    68281 tctgcctttg caggccgtga attagtctta gatgcctacc accatgccat ccaagaacac
    68341 taccgcttct tcagttttgg tgacgccatg tttatttatt gagaaagaat ttctctaaat
    68401 cttctaatac caataaatcg ctaagatatt atttcaaaga acatctacaa ttgaaactct
    68461 agctagctgt agaagacgcc tagtacattg aaattaaaat gcttccccct agcttcgaaa
    68521 atattgccat agattgcgtt gactctccaa attgattcat ctatatttta tttcagcttc
    68581 ctatattttc ttcgctgttt gtaaatcaaa atgcaagaca catgagtagc accatatttg
    68641 ttactcttat ctgtcctctc aagagactat tatgagttat ttcagaatca ttcactactt
    68701 tgaccctgac tctccttagt ctcaaaatca aagacttata ctcttcaaaa atctcttcaa
    68761 accgcgtcaa cgtcaccttg gattatatat gtgactgact tcgtcagttc tatctacaac
    68821 ctcaaagcag tactttgagc aacctgcgac tagttttcta gtttgctctt tgattttcat
    68881 tgagtattaa acaaaaagtg aacaaatcta aattctaatg tacagaagac taggcttgtt
    68941 cactttttta tagtcgctat aagatgacct tatctatagt tttttatata taattatata
    69001 ttcagacata ctattatcaa ttttgtcgca gggaggaatc tgttaacgca cccattcacc
    69061 attatcattg actctatagc catctatact tgtattgacc gctaactcac ccgatgcatt
    69121 tacataatac catttaccac caacttggaa ccattgattg actttcatag aaccgttgct
    69181 gttgaggtag taccatgaac cattaacttg tacccaacct gttgccatgg aaccatcagt
    69241 attat
//
LOCUS       DAVDFK010000007        67693 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.07, whole genome shotgun sequence.
ACCESSION   DAVDFK010000007 DAVDFK010000000
VERSION     DAVDFK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.07"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..422
                     /locus_tag="VUR04_000535"
     CDS             <1..422
                     /locus_tag="VUR04_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5340480.1"
                     /translation="SDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHF
                     QNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIK
                     LIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
     gene            complement(558..761)
                     /locus_tag="VUR04_000536"
     CDS             complement(558..761)
                     /locus_tag="VUR04_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET5340481.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(792..1400)
                     /locus_tag="VUR04_000537"
     CDS             complement(792..1400)
                     /locus_tag="VUR04_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5340482.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(1439..1609)
                     /locus_tag="VUR04_000538"
     CDS             complement(1439..1609)
                     /locus_tag="VUR04_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET5340483.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(1621..2187)
                     /gene="amaP"
                     /locus_tag="VUR04_000539"
     CDS             complement(1621..2187)
                     /gene="amaP"
                     /locus_tag="VUR04_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET5340484.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2271..2468)
                     /locus_tag="VUR04_000540"
     CDS             complement(2271..2468)
                     /locus_tag="VUR04_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET5340485.1"
                     /translation="MAGKITKKSSSMGIIANVFAGLVGASAGQSLLGSWGSSIAGMAL
                     LPSIVGAAIVITVVSFFTGRK"
     gene            2879..4360
                     /locus_tag="VUR04_000541"
     CDS             2879..4360
                     /locus_tag="VUR04_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5340486.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            4722..5717
                     /locus_tag="VUR04_000542"
     CDS             4722..5717
                     /locus_tag="VUR04_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5340487.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            5844..7154
                     /locus_tag="VUR04_000543"
     CDS             5844..7154
                     /locus_tag="VUR04_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET5340488.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            7250..8152
                     /locus_tag="VUR04_000544"
     CDS             7250..8152
                     /locus_tag="VUR04_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5340489.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYTFTDYYLLTPDERKFVGFENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            8154..8999
                     /locus_tag="VUR04_000545"
     CDS             8154..8999
                     /locus_tag="VUR04_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5340490.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRFAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            9009..10328
                     /locus_tag="VUR04_000546"
     CDS             9009..10328
                     /locus_tag="VUR04_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET5340491.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(10536..10608)
                     /locus_tag="VUR04_000547"
     tRNA            complement(10536..10608)
                     /locus_tag="VUR04_000547"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10573..10575),aa:Lys,seq:ctt)
     gene            complement(10873..12144)
                     /locus_tag="VUR04_000548"
     CDS             complement(10873..12144)
                     /locus_tag="VUR04_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET5340492.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANCLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            12442..12657
                     /locus_tag="VUR04_000549"
     CDS             12442..12657
                     /locus_tag="VUR04_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340493.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            12822..13001
                     /locus_tag="VUR04_000550"
     CDS             12822..13001
                     /locus_tag="VUR04_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340494.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            13138..13317
                     /locus_tag="VUR04_000551"
     CDS             13138..13317
                     /locus_tag="VUR04_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET5340495.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            13354..13806
                     /locus_tag="VUR04_000552"
     CDS             13354..13806
                     /locus_tag="VUR04_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET5340496.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGTSEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            14097..14567
                     /locus_tag="VUR04_000553"
     CDS             14097..14567
                     /locus_tag="VUR04_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET5340497.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            14586..15674
                     /locus_tag="VUR04_000554"
     CDS             14586..15674
                     /locus_tag="VUR04_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET5340498.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            15655..16083
                     /locus_tag="VUR04_000555"
     CDS             15655..16083
                     /locus_tag="VUR04_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5340499.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELSGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            16218..17171
                     /locus_tag="VUR04_000556"
     CDS             16218..17171
                     /locus_tag="VUR04_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET5340500.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVADGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            17173..17916
                     /locus_tag="VUR04_000557"
     CDS             17173..17916
                     /locus_tag="VUR04_000557"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET5340501.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSSLSVLVELEK"
     gene            17927..19723
                     /gene="pepF"
                     /locus_tag="VUR04_000558"
     CDS             17927..19723
                     /gene="pepF"
                     /locus_tag="VUR04_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET5340502.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            19969..20760
                     /locus_tag="VUR04_000559"
     CDS             19969..20760
                     /locus_tag="VUR04_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET5340503.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            20871..21539
                     /locus_tag="VUR04_000560"
     CDS             20871..21539
                     /locus_tag="VUR04_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET5340504.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(21792..22325)
                     /gene="queF"
                     /locus_tag="VUR04_000561"
     CDS             complement(21792..22325)
                     /gene="queF"
                     /locus_tag="VUR04_000561"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET5340505.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(22630..22944)
                     /gene="trxA"
                     /locus_tag="VUR04_000562"
     CDS             complement(22630..22944)
                     /gene="trxA"
                     /locus_tag="VUR04_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5340506.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(22961..23182)
                     /locus_tag="VUR04_000563"
     CDS             complement(22961..23182)
                     /locus_tag="VUR04_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET5340507.1"
                     /translation="MIEITYIDASKNEKTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(23282..23662)
                     /locus_tag="VUR04_000564"
     CDS             complement(23282..23662)
                     /locus_tag="VUR04_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5340508.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(23806..24759)
                     /locus_tag="VUR04_000565"
     CDS             complement(23806..24759)
                     /locus_tag="VUR04_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET5340509.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(24827..26036)
                     /gene="sstT"
                     /locus_tag="VUR04_000566"
                     /pseudo
     CDS             complement(24827..26036)
                     /gene="sstT"
                     /locus_tag="VUR04_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            26175..26735
                     /locus_tag="VUR04_000567"
     CDS             26175..26735
                     /locus_tag="VUR04_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET5340510.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            26792..27700
                     /locus_tag="VUR04_000568"
     CDS             26792..27700
                     /locus_tag="VUR04_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET5340511.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            27652..28242
                     /locus_tag="VUR04_000569"
     CDS             27652..28242
                     /locus_tag="VUR04_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET5340512.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            28245..29351
                     /gene="yqeH"
                     /locus_tag="VUR04_000570"
     CDS             28245..29351
                     /gene="yqeH"
                     /locus_tag="VUR04_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET5340513.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEYY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            29566..29877
                     /gene="yhbY"
                     /locus_tag="VUR04_000571"
     CDS             29566..29877
                     /gene="yhbY"
                     /locus_tag="VUR04_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET5340514.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            29929..30558
                     /locus_tag="VUR04_000572"
     CDS             29929..30558
                     /locus_tag="VUR04_000572"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET5340515.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            30558..31151
                     /gene="yqeK"
                     /locus_tag="VUR04_000573"
     CDS             30558..31151
                     /gene="yqeK"
                     /locus_tag="VUR04_000573"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET5340516.1"
                     /translation="MAYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            31152..31652
                     /locus_tag="VUR04_000574"
     CDS             31152..31652
                     /locus_tag="VUR04_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET5340517.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEARTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            31665..32018
                     /gene="rsfS"
                     /locus_tag="VUR04_000575"
     CDS             31665..32018
                     /gene="rsfS"
                     /locus_tag="VUR04_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET5340518.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            32121..32867
                     /locus_tag="VUR04_000576"
     CDS             32121..32867
                     /locus_tag="VUR04_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5340519.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            32877..33974
                     /locus_tag="VUR04_000577"
     CDS             32877..33974
                     /locus_tag="VUR04_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET5340520.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILVQARESNLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            34212..34466
                     /locus_tag="VUR04_000578"
     CDS             34212..34466
                     /locus_tag="VUR04_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET5340521.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
     gene            34470..34724
                     /locus_tag="VUR04_000579"
     CDS             34470..34724
                     /locus_tag="VUR04_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HET5340522.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            34915..36528
                     /locus_tag="VUR04_000580"
     CDS             34915..36528
                     /locus_tag="VUR04_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET5340523.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            36658..37284
                     /gene="gmk"
                     /locus_tag="VUR04_000581"
     CDS             36658..37284
                     /gene="gmk"
                     /locus_tag="VUR04_000581"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET5340524.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            37309..37623
                     /locus_tag="VUR04_000582"
     CDS             37309..37623
                     /locus_tag="VUR04_000582"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET5340525.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            37689..40085
                     /locus_tag="VUR04_000583"
     CDS             37689..40085
                     /locus_tag="VUR04_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET5340526.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQAHDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            40098..41033
                     /locus_tag="VUR04_000584"
     CDS             40098..41033
                     /locus_tag="VUR04_000584"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET5340527.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            41026..42339
                     /gene="rsmB"
                     /locus_tag="VUR04_000585"
     CDS             41026..42339
                     /gene="rsmB"
                     /locus_tag="VUR04_000585"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET5340528.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            42354..43094
                     /locus_tag="VUR04_000586"
     CDS             42354..43094
                     /locus_tag="VUR04_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET5340529.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            43091..45070
                     /gene="pknB"
                     /locus_tag="VUR04_000587"
     CDS             43091..45070
                     /gene="pknB"
                     /locus_tag="VUR04_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET5340530.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEVVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            45185..45943
                     /locus_tag="VUR04_000588"
     CDS             45185..45943
                     /locus_tag="VUR04_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET5340531.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            45945..46394
                     /locus_tag="VUR04_000589"
     CDS             45945..46394
                     /locus_tag="VUR04_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET5340532.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            46456..47082
                     /locus_tag="VUR04_000590"
                     /pseudo
     CDS             46456..47082
                     /locus_tag="VUR04_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            47150..47491
                     /locus_tag="VUR04_000591"
     CDS             47150..47491
                     /locus_tag="VUR04_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340533.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSNQSFFKMMTNKRLDLVNQVFF
                     LSFTAICDKIV"
     gene            47529..48701
                     /locus_tag="VUR04_000592"
     CDS             47529..48701
                     /locus_tag="VUR04_000592"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET5340534.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            48701..49975
                     /locus_tag="VUR04_000593"
     CDS             48701..49975
                     /locus_tag="VUR04_000593"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET5340535.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(50010..50975)
                     /locus_tag="VUR04_000594"
     CDS             complement(50010..50975)
                     /locus_tag="VUR04_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5340536.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(50956..52410)
                     /locus_tag="VUR04_000595"
     CDS             complement(50956..52410)
                     /locus_tag="VUR04_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET5340537.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            52787..54670
                     /locus_tag="VUR04_000596"
     CDS             52787..54670
                     /locus_tag="VUR04_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5340538.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     ILPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            54819..55706
                     /locus_tag="VUR04_000597"
     CDS             54819..55706
                     /locus_tag="VUR04_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5340539.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(55749..56366)
                     /locus_tag="VUR04_000598"
     CDS             complement(55749..56366)
                     /locus_tag="VUR04_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET5340540.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(56781..56969)
                     /locus_tag="VUR04_000599"
                     /pseudo
     CDS             complement(56781..56969)
                     /locus_tag="VUR04_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            57673..58566
                     /locus_tag="VUR04_000600"
     CDS             57673..58566
                     /locus_tag="VUR04_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340541.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            58563..59762
                     /locus_tag="VUR04_000601"
     CDS             58563..59762
                     /locus_tag="VUR04_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340542.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMTKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(60173..60940)
                     /locus_tag="VUR04_000602"
     CDS             complement(60173..60940)
                     /locus_tag="VUR04_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340543.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(60957..61652)
                     /locus_tag="VUR04_000603"
     CDS             complement(60957..61652)
                     /locus_tag="VUR04_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340544.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPNPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(61657..62022)
                     /locus_tag="VUR04_000604"
     CDS             complement(61657..62022)
                     /locus_tag="VUR04_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5340545.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHKLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            62162..62635
                     /gene="nrdR"
                     /locus_tag="VUR04_000605"
     CDS             62162..62635
                     /gene="nrdR"
                     /locus_tag="VUR04_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET5340546.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            62636..63805
                     /locus_tag="VUR04_000606"
     CDS             62636..63805
                     /locus_tag="VUR04_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET5340547.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            63806..64702
                     /gene="dnaI"
                     /locus_tag="VUR04_000607"
     CDS             63806..64702
                     /gene="dnaI"
                     /locus_tag="VUR04_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET5340548.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            64699..65412
                     /locus_tag="VUR04_000608"
     CDS             64699..65412
                     /locus_tag="VUR04_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET5340549.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            65426..66736
                     /gene="der"
                     /locus_tag="VUR04_000609"
     CDS             65426..66736
                     /gene="der"
                     /locus_tag="VUR04_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET5340550.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            66825..67160
                     /locus_tag="VUR04_000610"
     CDS             66825..67160
                     /locus_tag="VUR04_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340551.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            67300..67635
                     /locus_tag="VUR04_000611"
     CDS             67300..67635
                     /locus_tag="VUR04_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340552.1"
                     /translation="MEHLFKMIILLPCFYFFSWIERANRDSKIFSIFYYFYWIYITLY
                     ALFSLAWTVFSVLLFNIVLRNVADIKSWGVWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGGRH"
BASE COUNT        20375 a        12613 c        14970 g        19735 t
ORIGIN      
        1 tcagcgataa acgtttttat cgccctactt ttcgcatgca cttaacaaat aaagaaattc
       61 ttgacaagat tttaagctat tcagaagact tgaaacacca ctatcagatc tatcaactct
      121 tactttttca ctttcagaac aaagaccctg agaaattttt cggactcatt gaggacaatc
      181 tgaagcaggt tcatcctatt tttcagactg tctttaaaac ctttctaaag aacaaagaga
      241 aaatcgtcaa cgcccttcaa ctaccctatt caaacgccaa attggaagcg accaataatc
      301 tcatcaaact tatcaaacgc aatgcctttg gttttcgaaa ctttgaaaac ttcaaaaaac
      361 ggatttttat cgctctgaac atcaaaaaag aaaggacgaa atttgtcctt tctcaagctt
      421 agcttttctt caacccacta cagttgacaa agagccaaat taaaaagcta gggttccgca
      481 attgggaatc tctagctttt tgttttctga gaatcatctt gactaatgtt accaaaaaga
      541 taaagtaact tttaacctta tttatcgtcg ccactcaaca tgtttttaac accttctaca
      601 gcaccttcta cagcgtcttt agcgtcttcg gcaacttctt ttactttaga aacaactttt
      661 tcagctgctc cttctttttc cattttttca tcaccgatgg ctttcccaac accttcttta
      721 atagaacctt tagcttgatt taatttttct tctactgaca tgataatttc tcctgttata
      781 tttattttat cttagtttac acgagtgttt tcgtgagata ctacaccatt tgctgcacct
      841 ttaacagctt ctacaccttc gctaactttt tcttgaacag ttgagaaacc agatccaaga
      901 ccagatttag ctttttcgaa ttgttctgaa gtgaattctc ctgttgattc agcaacgtca
      961 gatacgcgat cttgaaggct tactgagtct gcttcatgct gttctttagt tttgatgtcg
     1021 acaacgttta cgttgatttc aacaatttcc aagtcagtca ttttagcaac ttctgaagat
     1081 acgatttctc tgatttctga atataaagct ggaacatttt tttggtactc aacaataacg
     1141 tttaagtcaa ctgcaacttg tgttttacca acttctacgt taacaccact tgttacgtca
     1201 tcgctgttaa cgattttttc tttaagattt gagaagaaac caccatcgat tcccaaaaga
     1261 cctgaaacgt tttctagtga aagaccaatg attttttgga taactttatc ttcgtaagta
     1321 agttcccctt tgatttcgtg agctacaaca gtagcatctt tcttttctac gttagtgttt
     1381 gtgttttttt cgtttgacat atgaaactcc tttaattaaa ttagtaattt ttattttttt
     1441 atttatctat atagtttttt tcgatatata atccagctgc aactcccagt gctcctaaaa
     1501 tcaatacaaa tattgttttg aagaagccaa aggagacaat caaacaagcc agaaatacgc
     1561 ctatgagacc agcgataatt ggatatcgat attgtttaag ccattccatt ttttacttcc
     1621 ttacttcaca cgactaacag tctttttgtt ttgaggtttt ggttggtaat tttttactgc
     1681 aacttcaagt tttacttgac gctcaatacc aaaaaactgc ttcaatccat tagttatttc
     1741 attttgaatt atttggcatc tgtcagcgat gttgtctgaa ggaagaattt taccttctac
     1801 atgaacgaaa catttatttt ttcgtaaatt tacatgaaca gttgggttct tgatcaatct
     1861 atgatcactc accaaacttc taacaaaacc ttcgattgcc gaattcttta attttaatgt
     1921 atcgttttta gtttcaagtt ggatttccaa gtaacgttta ggataaaaca tcacaactaa
     1981 aatggataat aaaactaaag ttgatagaac cactgtcccc caaaagacat atctagcaag
     2041 atagaattca actacggagt tctgtctcca gctaagtaga tgaataccta gatcactaac
     2101 ttgatgataa tctatcaaaa caggaaggaa aattgtcaag attaaaatac agaaaataat
     2161 gaaacatatt ttctttgctt ttgacatata caatcctttc gatttaacat ttaaactatt
     2221 tttcccgtca ttgatttaaa aatagtttgc taactttact ggcgaaaagt ttactttcta
     2281 cctgtaaaga atgacactac agtaatcaca atcgctgcac ctacaataga tgggagcaaa
     2341 gccattccag cgattgatga accccaacta cctaaaagag attgtcctgc agatgccccg
     2401 actaaaccag cgaatacatt tgcgatgatt cccatagaac tacttttttt agtgatttta
     2461 cctgccaaga gaccaataag acctccagca ataattgatc acaacactgc ctaccctcct
     2521 tttttatttt aatatcaaaa aatcaatttc tttgattatt actattatat aactttaata
     2581 tagaaaagtc aattatttcg attgttatta ttatataatt ttaaaaaatc aaattcttta
     2641 attgttgcta ttatataatt tttaaaatta aaaatataat ctttagactt gaatttgatt
     2701 ctgtattcac gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta
     2761 gtgttattat acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc
     2821 tttgtggtat aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat
     2881 gagagattta ttatctaaaa aaagtcatag gcaattagaa ttattagaat tactatttga
     2941 acataaacgt tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc
     3001 agtcaaagat gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc
     3061 tactaatggt atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca
     3121 tttctttaaa cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg
     3181 tcaagctgag agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat
     3241 tagccaaatc aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt
     3301 tcaaatcatt ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa
     3361 atattatttc ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt
     3421 agaattggtt tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa
     3481 gttgctccta gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa
     3541 agattctttt aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt
     3601 tgctcagagt tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt
     3661 atttgtgtct tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt
     3721 aaaaaaggat agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat
     3781 ttcagtcaag tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa
     3841 taccgcacat ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg
     3901 gaatacaatc aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga
     3961 gctttctcac tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct
     4021 atcttatacc ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc
     4081 taaactaaag gttttagtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga
     4141 gacactttct tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt
     4201 atcaaaggaa tctttagaag attcacctta tgatatcatt atttctaatt ttattattcc
     4261 tcctattgaa aataagagac tcatctattc aaataatata aacacggtct cactcatata
     4321 tttgttaaat gccatgatgt ttattcgatt agatgagtaa ccaaaaataa caaaaaaacg
     4381 ctatttcgcg tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg
     4441 tttttgttaa gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc
     4501 tctaaaactc ttgctttttt tgtagaagat acgaaaaaag ccataaaacc aaggcttttc
     4561 ctgttttatg tagatgttta cacatgaaaa ttgaagtatt ttcaaaagct aattggagtg
     4621 attttattca tgatgggata aatgatctgg ccaaaaatga ttgagaaata gttgcttaaa
     4681 aagcatttgc atgatactat atattgaaag gaggtgataa tatggtagaa caaagaaaat
     4741 caattaccat gaaagatgtt gctttagaag caggagttag tgttggaact gtttcacgtg
     4801 taattaataa agaaaaagga attaaagaag taactttaag gaaagttcaa agggctataa
     4861 aaacattgga ctatatccct gataattatg ctcgaggtat gaaaaagaat agaacagaaa
     4921 ctatcgcttt gattattccg agcatatggc atccattttt ttcggagttt gcctatcatg
     4981 ttgagaaaga gttattaaaa tataattata aattatttat ttgtaacgct gatagcgatt
     5041 cacaaaatga aatcgaatat atcgaaatgt tgaaacaaaa taaagtggat ggaattattg
     5101 gtattacata ttctgatatt gacaaatata ttttatctga tttaccgttt gtaagtatag
     5161 atagacattt ttcggaaaat gtatgctatg ttacttcagc aaattacaaa ggaggacaaa
     5221 ctgcagcaga ggaactggtt agaagggata ataagcacct tgcttttatt ggttcaatta
     5281 atatgtatga gaatgagact atactcagaa gtaaaggatt cagagaaaaa gctaaggaat
     5341 taggagtaga tgtctataat tttgaaatga aagaaccttt aataaatcct gaagatcaga
     5401 taagaatttt tttgcaatct cataaagaaa ttgatggtat atttacaata aatgatatga
     5461 tggctctgag agttattagt gttatgaaag aactggggaa aatagcacct gatgattacc
     5521 agataattgg gtttgatggt ttaaaaactt ctgtcgatca atcttatcta gtgtctacaa
     5581 tagttcaaga tattggtatg atggcaaaag aatctgttgc aatgatactg aaaatgatta
     5641 agcgagaaga gattctagaa aaacgaatcg taattcccac atatttttgg ggagataaaa
     5701 caacaaaaaa aatttaaaaa gcgcttgaca attaatgaaa gcgctgttat aatataatca
     5761 acaaatgaaa cgtttcaaaa ataggctaga agcttgttta aaaaataaat aaaaaatgaa
     5821 acgtttcaaa aaggaggaaa atgatgcgta aaggtacaat gttatctgtt gttgcggggc
     5881 tatcgttagc tatacttgca ggttgtagtg gaggaactaa ctcaaaacaa gcgagttctt
     5941 caaatgatat taaagtctgg gtacaattct ctgacgaaac aaatgaagga aaagcttggc
     6001 aaaaagttgt tgataacttt aatcaatcag gaaaaagtaa gtataaggtt gtaactgagt
     6061 atattcctcg tagtggtagt ggtggaggat atgaagacaa ggttaatgct gctattacga
     6121 ctaatagtct tccagatgtt attacccttg atggaccaaa tacggcagct tatgcaaaat
     6181 ctaaagtaat tactccgcta gatgattatc taaaagataa taatatggat gatgttttgg
     6241 acagtattaa acaacaggga acttataatg ggaaattcta tgcatttgga ttttctgaat
     6301 cgaatgttgg tgtttattac aataaaaaaa tgttcaaaga ggccggaatt gcggaatcag
     6361 agcttccaac gctagaaaag ccatggacat gggacgaatt taatacgatt gctaaaaaat
     6421 tgaaagatca ttataacaaa ccagcaattg attttcgtat taattcaaac gatgaaatgt
     6481 tgccatatgc ttatatgccg ttgatttggt caaataatgg ttctgtcgta aacgaagatg
     6541 gaacaaaggc agaaggatac ttcaactcca aagagagtgt agaagcagtt caattcattc
     6601 aaaatcttgt aaaagaaggc tatacaactg ttagtccagt cgaaaaaggt tttgaaacag
     6661 gagagtatcc aatgcttttg agtggttctt ggacgattgc tgacatgaat acaaactaca
     6721 aagatattga ttttggtatc cttccttacc cagtatctag taagacgaaa aaattagtat
     6781 ccccttcagg tagttggcaa ttagctgtga cgacaaaatc tgataaaaaa gaggccgcat
     6841 ctgaatttgt taaatttgct acaaatacag aatcaagtga aattattagc ttggggaatt
     6901 cggtccttcc aattcgtaaa tctacaattg aaaatatcaa agataaagta tccgaaccaa
     6961 tgcgtttctt gatggaacaa aattcaaaaa cagctcatgc tcgcccagtt gtcgtagcat
     7021 atcctcaggt ttctcgagct tttcaacaag caatgcaaga tattagctat tatgaagaaa
     7081 atccaaatgt gcaaaaagtc ttggatactc gtacaaaaga aatgcaaact gctattgatc
     7141 agtcactcaa ataatctgta aaaaagaagg tggaaggaaa atgtttggaa ctaccttccc
     7201 ctttcttgtt aatagcctag tttgatatat atgattaaag gagatggata tgagtaaaga
     7261 aactgttgtg gatacaaaaa gacgtgaaaa aataaaagat aacatactag gttatagttt
     7321 tttagctcca gctttaattt tattaggtat ctttttggta attccagttg gaatggtcat
     7381 ttattacact tttacagatt attatttgtt gacaccagat gaaagaaaat ttgttggatt
     7441 tgagaatttt attcgattaa caaaagatcc gattttctta aagagcttct tgaatacttt
     7501 gaaatttgtt gtttggatta ttccagttca attgggagcg gccttaggaa tggctttgat
     7561 tgtcaataaa aagcgaaaag gaaatatgtt ttttaaagtg gctttttttg ctccagttgt
     7621 catgtccttg gtagttattt ctattctttg gctttatctt ttaaatccaa atagtggctt
     7681 attaaatgct attttaaata aggtaggtat tgcttctcaa cctttcttga ctagtcctaa
     7741 acaagctatg tatgcaattg tttttgtttc tgcttggcag ggtgcaggtt atcagatgct
     7801 tttattttta ggaggaatgc agaatattcc acaagatgtc tatgaagctg ctgaattaga
     7861 tggattctca aaatgggctc agtttcgtta tatcacgatg cccctactaa aaccaacagc
     7921 cctgtttgta ttgttaacaa ctttaatttc tgcttttaag ctgattgtac aaccaatggt
     7981 tatgacgcaa ggtgggccat taaactcaac aattactatg gtgtactata tttatcaaca
     8041 aggttttact gatcgtcttg taggatattc tagctcaatc gctttagtat ttacaacgtt
     8101 aattggtatg attagcttag tacaacgtcg cgttctgaag gaggatgact aagatgaaac
     8161 gatttaaacc aacaacaatc ttagaatata ttctgttaac tttattggca ggactcttcc
     8221 tttttcctat ggtttggatg gtagtttcag ctatgaagcc agaagcggat gtttataaaa
     8281 atttgactag ttggcaagcc ttcttaccaa gtttaaatcc cgctgattgg tttaaacctt
     8341 atcaggaagt atttgagcgc tttagtattt ttacatatct agggaacagc attttttatg
     8401 ctggaacgtt tgctattggt tctattattg tcaatgcact ggccggtttt gcttttgcaa
     8461 aagtcaattt ttcaggtaag aaaattttat ttggtttctt acttgcttta cttattattc
     8521 cagtggaaac tgtgttaatt ccacaattta ccattatcaa ttccttaggt ttggtcaata
     8581 atcgttttgc agttattatt ccaggattgg cgagtgtatt taatatttac ttatttagga
     8641 atttctttat tgcaattcca gaagagattc ttgagtctgc aaagatggac ggagcaagta
     8701 tcgttagaat tttctttaga attatgcttc caatgtctaa acctgcagtt gctacagttg
     8761 gtgttttatc atttatttca agctggaatg attatatctg gccattgatg gttttgacag
     8821 attcttctaa attttcaatg caggttgcaa ttacaactat taatacaact caaccagttt
     8881 atatcaatca ggtaatggct gtattaacta tttcaacgat tccgttgatt ttggtctatg
     8941 tagtcgctca gaaatatatt gttcaaggtc tgggtggttc cggaactgga ataaaatagg
     9001 atatacttat gataaataaa acatttacag tagaaaaagc caatcgtttt atagcagaaa
     9061 ataaacatct cgttaatact caatataagc ctgaagaaca tttttcagct gagattggtt
     9121 ggatcaatga tccaaatgga tttgtttatt ttcgtggaga ataccatctc ttttatcaat
     9181 tctatccata tgatagtgtt tggggaccta tgcactgggg acatgctaaa agtaaggact
     9241 tggtgacttg ggagcacttg ccagtggcac ttgctcctga ccaagattat gaccgaaatg
     9301 gttgtttctc aggctctgcc attgtcaagg atgatcgcct ctggctcatg tacactgggc
     9361 atatcgaaga aaaaaccggt gtccgccaag tgcaaaatat ggcattttca gatgacggga
     9421 ttcactttga aaagatttcc caaaatccag ttgtaactgg aacagacttg ccagatgagt
     9481 tgattgctgc tgatttccgt gatccaaaac tctttgaaaa agatggacgc tattactccg
     9541 tagtagctgc caaacacaag aataatgtgg gctgtatcgt tctactaggg tccgataacc
     9601 tagtagaatg gcagttcgaa tccatctttt taaaaggggt agaacaccaa ggctttatgt
     9661 gggaatgccc agattacttc gagttagatg ggaaagattg ccttattatg tcacccatgc
     9721 gttatcagcg tgagggagac tcatatcata acatcaactc atcgcttttg ttcacgggta
     9781 aggtagattg gggagaaaaa tgttttatcc cagaatcagt tcaagaaatt gatcatggcc
     9841 aagacttcta tgcgcctcaa acattgttgg acgatcaaaa tcgtcgtatc ctgattgctt
     9901 ggatgcagac atgggggcgt acccttccaa cccatgacca agaacacaaa tgggcatgtg
     9961 ccatgacttt acctagaatt ctaagattgg aagatggcaa actaagacaa ttccctgtta
    10021 aaaaaggcca atatcaaatc caaatagata aagattgtca ttaccactta ggaaatgata
    10081 tagattatct tgaatttggt tatgatagta atgcgcagca agtttacatt gatcgtagcc
    10141 atcttattca aaaaattcta ggtgaagaag aacaggacac tagtcgacgg tatgtagata
    10201 ttgaagctaa agaattggaa gttgttctag ataaaaattc catcgagatt tttgtcaatc
    10261 aaggtgaagc aagcttgact gcaacttatt acttaacggt gccagctgag ctatcacgaa
    10321 ttgattaaaa attaagttat ttctcctaaa gaaaaagttc tctttctaaa atagtggaaa
    10381 gaggactttt tgtgttttgg gtatataagc ttagtttatg gtatttgtaa aattggtgtt
    10441 ggattatgat ttaagctagt tttctaaaga atttgaaaaa aattttattt aagcaaaaaa
    10501 accttggttc caaggctttt cctgttgtat ttagatgccc cctacaggga tcgaacctgt
    10561 gacccacgga ttaagagtcc gctgctctgc cagctgagct aaggaggcaa agaaaaaagc
    10621 tgtattggtg ccgaaacttc acggtttgta ttgaacccgc gcaattaagc aggtgggcaa
    10681 ctcgctctaa ctgaagctgt ttccgtgtga gacggcctac atgctgttag aagacttttg
    10741 tttccctaat aatacaaaaa atagtcggtc aacacttaag tgtgaagtcg tacaccacag
    10801 cgtttctata tttatatgat accacttttt caaaaaaaat caagaggaaa gtgcaatttt
    10861 ttgaaaagga tttcagattt ttcgcaaatg gtcgatagct tcctttcttt gagccaaagc
    10921 ccgttcatat ttaccagtat cttctgcttg gaaatagtga tgattacgaa ttttttctgg
    10981 cagatagtct tgcttgaccc aatttccagg atagttgtgt ggatagagat agtcttgggc
    11041 attccccagt tccttgcttc cactgtagtg cccatcacgc aggtgtcgcg gaataggcaa
    11101 gtgccctgat gttttgaggt cagcaagtgc cttatccata gctacatagg ctgagttgga
    11161 ttttggagaa agggccaaat caatcacgac attggcaatg agaatgcggg cttcggggaa
    11221 accaatcctt tgtgcagcat ccagagcagt cacggtatga atctgagcct caggattggc
    11281 taagccgata tcttcatagg cgataacagt caagcgacga gcgagactag gcagatcccc
    11341 agcctcaatc aagcgggcag tatagtggag actggcatcc acatctgagc cacgaataga
    11401 cttttgcagg gcagatagaa catcatagtg accgtctcca tccttgtcca tagtgatgta
    11461 gcttctctga agactatttt ccatgatgtc taaggtgatg tggcgaatgc cctcgtcatt
    11521 ctcaggggta gatagaacag ccaagtccag tgagttaaag gcagagcgaa ggtctccgtt
    11581 tgtagaggtt gcgatgaaat ccagcgcatc ctcatctagt tctattggaa aatcaaaacc
    11641 acgttcaggg ttacttagag ctatctgcag ggcctctttg acgtcttggt tagacagagg
    11701 ttccaactcg aaaatttgaa ctcggctacg aatggcagga gtgacagaga agaaaggatt
    11761 ttcagtcgtt gctccaatca tgatgaccag tccactttcc aagagaggca agaggaagtc
    11821 ttgcttggtc ttatctagtc gatgaatttc gtctagcaat aggacgagac caccagaaaa
    11881 tttagcttct tccgagattt cttgcagtcg ctttttacta tcaactgtcg cattgaaagt
    11941 tcgaaaggca tacttggtcg ttccagcgat ggcagaggca atactggttt tgccgattcc
    12001 aggagggcca tatagaatca tggaggacag gcagttggct tccaccatgc ggcggatgat
    12061 ttttccaggt ccgaccagat gctcctgacc gatgacctgg tcgatggttt tagggcgcat
    12121 gcgaagcgcg agattgtctg gcatagcagt cctttctaac gtggatttga gtagaatgac
    12181 tcatctacta tatcttacta tgtccattct agcctattag ttgtgatatt tcaatggttt
    12241 tgtaataatc agggagtgag atagaatctt ttttactatt taatttaatg aggagaggta
    12301 tcagcatgag agatttgatt ttccttaaag ctcaaaatag gatagttgag cctaaagaag
    12361 tggaagtgct gacttgagaa ataatattgc tgaatgtcat tgtatgaact ataatgaaaa
    12421 gagaggtgat aagcaatgga aatgatggaa ctaccaagtc aggaaatttt gatttttaca
    12481 aaacaaattc gtcattggat tcttagtgat caagttattt cagggaaaag aaaacttttc
    12541 ttccgggaag atactccaaa agagatttta gatttgtacg aaaacattaa atctaaactt
    12601 gattttgctt accaagaagt tcattctaat aatgggttga aaaaatatga aaaatagaat
    12661 aattgatgtt tttgaagtag taaatcgcct ccttgtaata actgttgaaa atcctgattt
    12721 cgaagacttg agagttaatc atactcaatg aaaatcaaag agcaaactag gaaactagcc
    12781 gcaggctgta cttgagtacg gtaaggcgac gttgacgtgg tttgaatttg attttcgaag
    12841 agtatcagtt tgtaaaaatt ggagataaaa aatatagagt acgcagtgtt cctatgattc
    12901 attcaactcc gcctcaatct gtcttagatc gagatacttt tacaattgac tatacagatg
    12961 atgaattgct cgataaagaa gcagttttta ctactcatta gaaaaatagg tatgaataaa
    13021 ttggcttccc ttagaaccac atctaggggc ttttatgtat aatagaataa taagtatcac
    13081 tcctttacaa tacgtgtaac acgtgttata atggtgttgt caggaggtaa aagcgctatg
    13141 cctatgacac aaaaagagat ggttaaactc cttacggccc atggttggat aaagactaga
    13201 ggcggtaaag gctcccatat taaaatggaa aagcaagggg aaagacctat cacaatcctt
    13261 catggtgagc tgaataagta cactgaaaga gggataggaa agcaagctgg gttgtaaaat
    13321 tcagtccctg ctttttgata tggaggtagt gaaatgttag ttacgtatcc agctttattt
    13381 tattatgacg acacagacgg aacagaagcg acttattttg tccatttccc agattttgaa
    13441 tactcagcta cacaaggaga ggggacttct gaggctttgg ctatggggtc ggagtggcta
    13501 gggataactg ttgcagattt gatagagagt gatggagagt tacctcagcc atcagatatc
    13561 aatagcttgt ctttaattga taatgatcct tttaaagatg atgaagattt cgtgtcaacc
    13621 tatgaccttg ataaatcttt tatttctatg gtatctgttg atgtatcaga atacctagga
    13681 agtcaggaac ccattaaaaa gactttgacc ataccaaaat gggcagataa gttgggacga
    13741 gaaatgggac ttaacttttc tcagactttg acagacgcta ttgcagataa gaaagttcaa
    13801 gcctaagatt aagcgtggta tcgtggtaat agtcaataaa aaagcacgtc cacttgtgct
    13861 agttactcgc ctattgattt tatagattta ttagcccttt cgcgggcttt ttatattgat
    13921 ttttatgaga aatgaagaaa tcagactttt aagaaaatca ctgataccaa gggtttaaat
    13981 gaggtaatat ggtataatta ggacataaaa taattttgtg gtaagatggt agtatctatt
    14041 ttagcatatt tccgagcaat cggggcgatt aaagagtcgc atagaaagag gacaaaatgg
    14101 caacatacgg atttttagat gttttagagg aagagttgga caagaacttt ccctttgact
    14161 ttgagattag ctgggacaaa cgcaaccatg cggtagaagt gagttttcta ttggaagcac
    14221 aaaatgctgc aggtgtggag atggtggatg aagacggaga ggtttcatca gatgacattc
    14281 tttttgagga agcggtcctt ttctacaatc ctgctaagtc aaccgtcaat gcagaagact
    14341 atttaacggt tatcccttat ctacctaaaa aaggattttc tcgcgagttt ttagcttatt
    14401 ttgccctttt cctcaaagat actgcggaag ttgggctaga taccctcatg gactttttgg
    14461 aagatccaga agcagaggaa tttgttatgg aatggaatca agaagtcttt gaagaaggaa
    14521 aagttggctt ggaagaggga gaattttatc cttatccaag atactaggag ttggttggag
    14581 gtgttatgaa gaaaattggg acttatttgg tttatgtgct agctgttgtc tttattatgc
    14641 tagcttttgc ttgtggaaca atcgcatttg cagagttggg gtattccgca gttttagcct
    14701 ttacttttgg ttatgccttc gctcttctaa gcatgtattt aatctttatt cttcatgagc
    14761 tgggtcatgc tttttgtggc tacttgacag gctatcggct ggtggctttt ggattaggac
    14821 attttatttt gaccaaaaag tcaggcaggt ttcatcttag tagaacagcc attctgaaaa
    14881 atgttggtgc tcaatacatt ggtttaaaag aggatgaaag cgatcaaaga atcatcctga
    14941 tgctttcagg aggcttgatg gttcatctcg gcttgatatt attggcgata gtgtttggat
    15001 ttttgacaag aagctggtat tttgcaggga cttggatttt tcttaattta tctttcttcc
    15061 taaataacat tttgccagtc gacatcaccg atggagcaaa aatttgggaa ttactacaac
    15121 accctgaaaa taccaaatac gcctacctgg tattgagaca ttctgctcaa actttgctgg
    15181 ctcctcaaga atatgatttg aaagactttg ttcaagcagt tcctgaggat gcacgaggga
    15241 gttttgcgga tggtgtatta ggtatgcaag gtgaagtttc cattttggaa gggaaggaag
    15301 aagtagctaa acagcagttt caagcattac ttgagaggac aactactccg atgatgcaga
    15361 cagttgccca actatccctg cttcatatcg ccttgttgga aggagatttt gagcaagcgg
    15421 agcaatatgc tagtattcga caggtcaaat cgtttctgtc tctcaaactg tccaatcttc
    15481 aagtgataca agcctggtat caattaaagg tgaagaaaga tgtagatcga actcgtaagg
    15541 ctctcaagat tgctagacag aaaatggata gtagtcgaat gttgagggac gagaaacgct
    15601 attatgaaaa cttgttagca gagctggaaa aggaaatgtt agaaggaact gaagatggaa
    15661 ctagaaattt ctgatttcca aggttgcaag attgccctct tttgtgggga taagctactg
    15721 acgattttgc gtgatgacaa ggacgatatc ccttgtccca acatgtggga gttgtcaggt
    15781 ggtggccgtg aaggggacga aagccctttt gaatgcgctc ggcgtgaagt ttatgaggaa
    15841 ctgggaattc atttagatga agactgtctg ctttggagca agatttatcc tagcgtaatt
    15901 tttaaaggca agaaatcggt ctttatggtt ggtcagctaa gacaagaaca atttgacaat
    15961 atcatcttcg gagatgaagg acagggctat cagctgatga atgttgagga atttcttagt
    16021 tccagtcaag ttgtgcctca gttgcaagag agattaaaag attatttaaa agtaagtgat
    16081 tagaaaggat ggttcagtta catttctaaa ctgaacccgc cctaaacact gtgccaaaaa
    16141 gataaacttc tcttagacac aagcgtcttc agagaatttc ctattttggt tttgtgtttt
    16201 acgggcttgg tatcttaatg atggaaacat ggcaagagtt aaaagttaca gtgaagcgtg
    16261 agggagagga gttggtttcc aatctcttga ttgagctggg agcgcaaggt gttgcgattg
    16321 aagacagtat ggactatgtg ggaaatgttg accgcttcgg cgagattttc ccagaggtcg
    16381 agcagcaaga agaaatcgta gtgacagcct actaccctga cacggtggat gtgacagtgg
    16441 ttgaggcgga cttgcaggct cgcatatcag aattgacgga ttttatggat ttgggagagt
    16501 taaaaatagg tacgactgcc ttggctgagg aagactgggc agataactgg aagaaatact
    16561 atgagccagc tcgtatcact catgatttga ccatcgttcc ctcttggaca gactatgagg
    16621 cgactgcggg agaaaaaatt atcaagctgg atcctggcat ggcttttggt acgggaaccc
    16681 acccaactac caagatgagc atttttgcct tggaacaggt tcttcgtggt ggcgaaacgg
    16741 tgctagatgt gggaactggt tcaggggttc tctctattgc cagctcgctt ctgggggcta
    16801 aagaaatttt cgcctatgac ctggatgatg tggcagttcg tgtggctcag gaaaatattg
    16861 agctcaaccc tggcatggaa aatatccatg tagcggatgg agatttgctt aagggtgtgg
    16921 aaattgaggc agatgtgatt gtggctaata tcttggcgga tatcctcatt catctaatag
    16981 acgatgccta tcgtttggtt aaggacgaag gctacctgat catgagtggc attatcaagg
    17041 ataagtggga catggtgcgc gagtcggctg aatcagctgg atttttcctc gaaactcaca
    17101 tggttcaagg ggaatggaat acctgtgtct ttaagaaaac caaggatatc tctggtgtga
    17161 ttggaggcta gcatgcagca gtattttgta aaaggcagtg ctatctctcc tgtcactatc
    17221 gaggacaagg aaaccagtaa gcatatgttt caggttatgc gcttgaaaga agaggatgag
    17281 gttaccttag tctttgatga tggcatcaag cgcttggcgc gcgtgctgga tatggaaaat
    17341 cgtcagtttg agttggtcca agaattaaat gacaatgtgg aactaccagt ccaagtgacc
    17401 atcgcatctg gatttcccaa gggagacaag ctggagttca tcgctcaaaa agtaaccgaa
    17461 ctgggtgcta gccaaatctg ggcctttcct gcagactggt cagttgccaa gtgggatggc
    17521 aagaaattgg gtaaaaaagt tgaaaaacta gaaaaaattg cccttggagc agccgagcaa
    17581 agcaagcgta atattgtacc aagtattaaa cttttcgaga aaaaagcaga ttttctagct
    17641 cagctggacc agtttgactc tatcatagta gcctatgaag aatcagctaa agaaggagaa
    17701 gccgctgcgc ttctgcaagc agtcactggt cttgaaacag gagccaaact gctctttatc
    17761 tttggtccag aaggcggtct ctcacctgca gaaatcgaaa gttttgaagc taagggagcc
    17821 gttttggtag gcctaggtcc tcgtattttg cgagcagaaa cagcaccgct ttacgcctta
    17881 tcatccctta gtgttttagt agaattagag aaataagagg aagaaaatgg aacaaaaaca
    17941 ccgttcagaa tttccagaga aggaactctg ggacttaaca gccctatacc aagaccgtga
    18001 ggatttcttg cgtgcaatcg agaaagctcg cgaagacatc aaccagttta gccgtgatta
    18061 caagggcaat cttcacactt ttgaggattt cgagaaggcc tttgcggaat tggaacagat
    18121 ctacattcag atgagccata ttggcaacta tgcttttatg cctcagacga cggactatag
    18181 caatgacgaa tttgccaata ttgcccaagc tgggatggaa tttgaaacag ctgccagcgt
    18241 agccttgacc ttctttgacg atgccttggt ggcagcagac gaggaagtct tggaccgttt
    18301 gggtaaattg ccacatttaa cagctgccat tcgtcaggct aaaatcaaaa aagcccacta
    18361 cttaggggca gatgtggaga aggccttgac aaatctcggt gaagtttttt acagtccgca
    18421 ggacatttat actaagatgc gagctgggga ttttgaaatg gctgactttg aagcccatgg
    18481 caagacctac aaaaacagct ttgtgaccta tgagaatttc taccaaaacc atgaggatgc
    18541 tgaggttcgt gagaaatcct tccgttcctt ctcagaggga cttcgtaagc accaaaatac
    18601 ggctgcagca gcctatctgg ctcaggtcaa gtctgaaaaa ctcttggctg atatgaaggg
    18661 atacgactct gtctttgact atcttctagc tgaacaagaa gtggaccgtg tcatgtttga
    18721 tcgccagatt gacctcatca tgaaggactt tgcaccagtc gctcagagat acctcaagca
    18781 tgttgccaag gtaaatggtc ttgaaaagat gacctttgca gactggaaat tggacttgga
    18841 cagcgccctg aatcctgaag tgactattga cgatgcctat gatttggtca tgaagtcggt
    18901 agaacctttg gggcaagaat attgtcagga agttgctcgt taccaagaag agcgctgggt
    18961 ggactttgct gctaacagtg gcaaggattc tggtggttat gcggcggacc catatcgcgt
    19021 acacccttat gtactcatga gctggacagg ccgtttgagc gatgtctata ccttgattca
    19081 tgaaatcggg cattctggtc aattcatctt ttcagacaat catcaaagct atttcaacgc
    19141 ccacatgtcg acctattatg ttgaagcacc gtcaaccttc aatgaattgc tactcagtga
    19201 ttacttggag aaccagtcta atgacccacg tcaaaaacgc ttcgctctgg ctcatcgctt
    19261 gacagacacc tacttccata actttatcac ccacctcttg gaagccgcct tccagcgtaa
    19321 ggtgtataca ttgattgaag aaggggagac ctttggagca agcaagctca acagcattat
    19381 gaaggaagtt ttgacggatt tctggggaga tgctattgaa attgacgatg atgcaactct
    19441 gacttggatg cgccaagctc actactatat gggcttgtat agttacactt actcagcagg
    19501 actagttatc tcgactgctg gttaccttca tctaaaacat tctgaaactg gagctgaaga
    19561 ctggctcaat ctcctcaaat caggtggtag caagacacca cttgagtcag ccatgattat
    19621 cggtgctgat atttcaacag acaaaccact ccgtgatacc atccaattct tgtctgacac
    19681 agttgaccag attatctcct atagtgctga gttgggagag taggggaata gaaaaatttt
    19741 ttagaatgat gtttatgggc ttgttaagcg tcattctatt tgtcttagtt gtagctattt
    19801 tcaaaaatgt cgttgaaggt cgtgatgtta aatttgaact tactgtagaa ctggtattga
    19861 tagttattta cgtcatttta tatcagattg tatttaattg agaattcaat attgagtcat
    19921 ttaagactgc ctttttgaac agttgctaga aatgtagagg tattgaccat gtatcaagat
    19981 ttactaagaa aaatagcaga agaaaaacca aattataacc aggaggaaat ccagtggttg
    20041 cttgatcatt tgggagatcc ttctccagaa attcgcgatg accttgtttt tacaagcttt
    20101 gctagaggga ttcaggaaga gctatttaca caggagcaat ttcattttat tgctgaaggg
    20161 gtttcatctg atgtaggact agataaagag attgataagg taggtctgcc aacacttgaa
    20221 cgttctttta gggcacttgt ttatgcaaat ctcttgtatg cagatgccaa ccagcaatcg
    20281 gttttttatc agggattaca attagaaatt cgtaatgtct tttcaaatca aggcttgcac
    20341 tatctttcaa aagaaaagga tacaacaggt ttctcaagtc agtatggttg ggttcatgct
    20401 tttgcacatg gagccgattt actgacagag gtggtctgtc atccagactt tcctataaac
    20461 agaattcatg aagtatttga catacttggc caactattta aaagaatgtc gattcgcttt
    20521 acagatgatg aggattggcg tttagcaaga gtgatctatg aacctatttt acaagggaag
    20581 ttggagcaag aacaagtagc ttcttggata aaaactgttg attttccgat agaagaaagg
    20641 gaggattttt ccaaattttc caactttaga tcctgtctgg tggaagtcta tgtccaactt
    20701 gaccagagaa atagtttaca agatgagttg aaagaagcta tccagtcttt tcaatactag
    20761 agattagcta atagttctat gattttcaaa aaatttccaa tcaattttct tgaaaccctt
    20821 tcctactttt gatagactag tatctagttt ttgaaaaaag gagaaagaaa atgaaaaaat
    20881 ttgttgctga gttaatcggt acgttcatgc ttgtgttcgt tgggacagga gctgttgttt
    20941 ttggaaatgg ttttgatggc cttggtcacc ttggaatcgc ctttgccttt ggtttggcaa
    21001 tcgtggtggc agcctactca atcggaactg tttcaggtgc tcacttgaac ccggctgttt
    21061 cgattgctat gtttgtaaac aaacgtttgt catcttcaga acttgtaaac tacatccttg
    21121 gtcaggttgt tggagctttc atcgcttctg gcgctgtctt cttcctcttg gctaactcag
    21181 gtatgtcaac tgctagtctt ggtgaaaatg ccttggcaaa cggtgtcact gtctttggtg
    21241 gtttcttgtt tgaagtcatc gcaactttct tgtttgtatt ggttatcatg actgtgactt
    21301 cagaaagtaa gggcaatggc gcgattgctg gtttggtaat cggtttgtca ttgatggcga
    21361 tgattcttgt cggattgaag attactggac tttcagtaaa cccagctcgt agcttggcac
    21421 cagctgtctt ggtaggcggc gcagcccttc aacaagtttg gattttcatc cttgcaccaa
    21481 tcgctggtgg agttcttgca gcccttgttg caaaaaattt ccttggaaca gaagaataat
    21541 tgaaactcaa aaagccttgc tcctcatctt gaggaacagg gctttttcgt atgatactct
    21601 tcgaaaatct cttcaaacca cgtcagcttc accttgccgt atagatgtta ctgacttcgt
    21661 cagttctatc tgcaacctca aaacagtgtt ttaagctgac ttcgtcagtt ctatctgcaa
    21721 cctcaaacac tgctttgagt aacctgcggc taacttccta gtttgctctt tgattttcat
    21781 tgagtatgac tttagcggtt gtcaattttc tctggataaa ggtcgtgttg gaagaggcgt
    21841 tgttctgcca agccctcata cttagttcct tgcttaccgt agttgtagta ggggtcgatt
    21901 gaaatgccac cgcgcggagt gaattttccc cagacttcta aatagcgagg gtctagcaag
    21961 ttgaccaagt ctttcccgat ggtgttgata cagttttcgt ggaaatctcc gtggtttcgg
    22021 tagctaaata gatatagttt gagggatttt gactcgacac agagcttgtc aggaatgtag
    22081 gaaatatgaa tcgtcgcaaa gtctggttga gcagtgattt gtcccagcag agacatatcg
    22141 aggatatggt gacgaatgcc ctgttcctta gcgatttctc tagtaatttg aatttcgagg
    22201 tgatgacgtt ggccgtaggc aaaggtgaca gcttcgactg tttcatagtg ttgcatggcc
    22261 cagaaaaggc aggttgttga atcttgacca ccactaaaga cgaccaaggc tgattgacgt
    22321 ttcatagtac tccttccaaa atgggaaatg ttcagagcat gcaaaaagct cctattaggg
    22381 agctaaaaaa taccaaatcg agttttttta gcgatggcat atcccaaaca tcgtaatatt
    22441 ctacttatat agtaaaatga aataagaaca ggacaaatcg atcaggacag ttaaatcgat
    22501 ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatctat tatagtctag
    22561 catatttttt gaaaaatggc aaagggcaag aaaaaagaga ccaaagaaag tacttggtct
    22621 ctcgtttgat tagctcaatt cagcaatgat ggccttgatt tgttctgctg tgtgaacacc
    22681 tgcaacttgt ttgacaactt ggccgtcttt tttgaagaga agagttggaa tagacatgat
    22741 tccaaaagca cgagctgtgt ttggattttc atcaacgtcc attttaacga ttttcaagac
    22801 atcttctgaa agttcttcag acaatttgtc caagattgga ccttgcatac gacatggacc
    22861 acaccaagtt gcccagaagt ctactaagac caaaccgtct tttgtttctt gttcgaatgt
    22921 tgcatctgta attgcttttg ccattgtatt tctccttttt ttagttatat tggcttaaat
    22981 cttgtttcat gagatagaag aagatatctc cataagtccc atggtagtcc aaattatgac
    23041 ccttgtaagt taatttttgg acagggtagt agtctgcgac gccgataagg caagcttgtt
    23101 gcgaacgttc aaagtcttca taagactcga aagtcacagt tttttcgttc ttgctggcat
    23161 ctatataggt aatttcaatc atgtttaaaa ctcctttgtt taatgctaac tttattttac
    23221 tccttataaa agagaatgtc aagaaaaatg attgcgcacg caactttttt taaaaatcat
    23281 cttaaatcaa gaaatccaaa cctgcttcca agctttcttc gacagttttt tgtagcgagg
    23341 ccagtgtctt ttgcccatca tttgtcaggc agataaaact agagcgtcta tcttgatggc
    23401 aacacatgcg actgagtaga ccgcaatttt tagcttccaa gcgagccacc atcctagaaa
    23461 ctgcgctcgg gctcagatga agtttatctg gcaggtcaat ctggcgtaga gatttttctt
    23521 cagccaagtc cagatagtag agcaggtaga actctttcaa ggtcagactt tgctcgctct
    23581 gttgggcaat ggtctcttcc aagagacttt caatttcttt ctgacgccga ttgaagtcaa
    23641 accatttttc caaataggtc atagtgtctc ctttcttttt agagtcataa tatagaagaa
    23701 agtccattaa cgggcagtct ctgcgtcaca agatgattgc gcatgcaata attatactac
    23761 ttttcaagaa tactggcaag ctctgttttt tagtggtttt attttttact gtctatattt
    23821 ttggtaaaaa tcaactttta cttggatgaa ggttttggct tcacgtagga gttgaagaag
    23881 ggtggcgcgg gtttcaaatt cttctcttgt cttgggcaga ctgcggttcc ggaagacttc
    23941 cagataacgt tcaatttcat ctagcaaatc agaagcagga ttggtctggc tcagttgacc
    24001 tgcaattttt gaaaagagtt gcgctaagat caggctttca ctggcggcaa ggtgacaagt
    24061 gttaatctgt tgggccatgt ttctcaggat acgactttgt cgctgtctca tctcaaagta
    24121 gtggatatgg tagtctgtct ggtgaaagag gtggtcagag tgatccaaat agacaagtct
    24181 gagggcttct ttcaaaagcg tgtctaattc tgctaccagc tgtgctcggt tgcgtccgtc
    24241 tcctctggat aaatagtatt tgaagcgctg gaggatatct tttaactttt cttccaccag
    24301 cgtgtggtag tgctggattt cctcttctcg tgaaggcata tagagattaa caagcaaggc
    24361 aaatcctgta ccaatagcaa agagaaggaa ttcattgact agaaggtctg gagaggttga
    24421 ctcttgaacc aagagatggc taaccaaaac agtgcttggt gtgatgccaa tttcccagcc
    24481 catcttgtag gctaaaggaa cgtagaaggc cagatagagg ccgagactcc agatatgaaa
    24541 tccgctcaag tgaaaagcta gaacaccgat agccagagct agaagcatag aaaaaagacg
    24601 attgcgagcc agttttaaag tacttctacg cgtatcagat aggctcaaga gagcgataat
    24661 tccagccgaa actgctgacg aaagattgag aaaataagca agcaggcagg caagacaggt
    24721 agctaagatg agcttggtcg tacgttggct aatagacata agaatttcct aataagttag
    24781 aataaaagcg taaaagacaa gacatgagca ggcttgcctt gatgagttat tttttacggg
    24841 ttgctgcgta ttcggcaacg gcggtaaaga ggacatctgt agaagagtta agggctgttt
    24901 cacatgagtc ttggatgaca ccaatcacaa aaccaacccc aacaacttgt atggcaatat
    24961 cgttagaaat accgaaaagg ctacaagcaa ctgggataag aaggagggaa cctccggcaa
    25021 tacctgaagc accacaggct gagatagctg ctaccacact gaggacaaag gctgtggcaa
    25081 agtcaacagg aattccaaga gtgttaactg taacaagggt caaaaggtta atggtaatcg
    25141 ctactccagc catattgata gtagaaccga gtgggataga aacagaatag gtatctgggt
    25201 tgagtccaag gtcatggcag agtttcatgt tgacaggaat gttagtcgca gaactacgag
    25261 tgaaaaaggc tgtcacaccg ctgacacgga ggcagttcca aactagaggg taaggattgc
    25321 gtctcataaa gaagaaggca atcaaagggt tgaccacagg ggcaacaaaa agcatagtcg
    25381 ttactaatgg aaccaataaa ataccatagt ttgcaaggct tccgactccc ttgtcagaaa
    25441 tggttttaaa aacaagacca aggattccaa atggagccag attgatgatc cattcgacaa
    25501 ttttagaagt cacgtcagcg atagttttta gcaattcttt actattttta ctggcttctc
    25561 tcatagcgat tccaaaaatg actgcccaag ataagattcc aatatagtta gcagtaaaca
    25621 gggcgttgac tgggttgtca accagtttga gcaagaggtt gctgaggacc tgcccaatcc
    25681 catctggtgg tgcaatttca gtattggcac tatttagggt aatttcaata gggacgatga
    25741 aacttgctag tacagctaca agagcagcgg cgaaagtccc tatcatagga tatacaagaa
    25801 aacaacagtt ttcatattgc tatcttgtcc cttttgatgt tgggaaaggg cattggcaac
    25861 gagggcaaag actaggatag gagcaacagc ttttagacct ccaacgaata aatccccgag
    25921 tagcccaatc cctgagagat taggaagggt cagtcctagg attccccata aagcatacca
    25981 atcaagatac gcttgacaag gcttgcctta ttccaagcat gaatgattct tttcataata
    26041 atctcctttt tgtgtagtga ttatgattat agtataaatg atagacaaaa tcaagaattt
    26101 tctgtctatt ttttgaatat ttatggagaa tgagactgat gaaaatatgg tataatgaaa
    26161 taaaggagtt ttatatgcaa aaatttattc aggcttatat tgaaaagcta gatgtgacaa
    26221 ccattatcga gaatattcta accaaggtca tttctctttt actgcttttg attgtatttt
    26281 atattgctaa aaaaatgctt cataccatgg tgcagagaat tgtcaaacct tctctaaaaa
    26341 tgtctcgtca tgatgtcgga cgccaaaaaa ccatctcacg tttactagaa aatgtgttta
    26401 attatacgct atatttcttt ttactctact gcattttgtc gattttaggt ttgccagttt
    26461 ctagtttgct ggctggagct ggtattgctg gggtagcgat tggtatggga gcccaaggct
    26521 ttctatctga tgtcatcaat ggctttttca tcctctttga acgtcaactg gatgtgggag
    26581 atgaggtcgt tctgacaaat ggaccgatta ctgtatcggg taaggttgtc agtgtgggaa
    26641 ttcgtacgac acagcttcgt agcgaggagc aagcccttca ctttgtccct aaccgaaata
    26701 tcacagttgt tagcaatttc tcacgcacag actagacctg ttattttaag taatttgtgg
    26761 tacaatagag ggagtttaat aaggagaaaa gatggtttta gaaaagcagt tgggcaatgg
    26821 ttgtacctgg atagacctag acctaggaaa gttgaataaa ctagaagacc tttctgaaat
    26881 ttacggtttg gacaaggaaa ccattgaata cgcactggat agaaacgagc gcgcccacat
    26941 ggattaccac cgtgaaagtg ggacggttac ctttatctat aatgtcctag acgtaaaaaa
    27001 ggacaaggcc tactatgaga cttttcccat gacctttatt gtcgagcatc gtcgcctgat
    27061 taccattagt aataccaaga acgcctatgt cattgaacag atgactcgtt atctggagag
    27121 ccatgacacg ctttcgattt ataagtttct ctttgccagt ctggaaatta tcagcaatgc
    27181 ctactatcct gtcattgagc agatggacaa gagtagggat gaggtcaatg acctcttgcg
    27241 ccagcgaact accaagaaaa acctctttgc cctgtctgat ttggagactg gtatggttta
    27301 tctgacggca gctgccaaac aaaatcggat tttgttagag catattcaag gtcatgcctt
    27361 gtatcgtagt tttgatgaga ttgagagaga acagtttgat gatgccatga ttgaggctca
    27421 tcagctggta tccatgacag acctaatctc tcagatttta cagcagcttt cagcctctta
    27481 caacaatatt ctaaacaata atctgaatga caatttgaca accttgacta tcatttcagt
    27541 cttgctagct gttttggcag tcgtgacagg ctttttcgga atgaatgttc ccttaccttt
    27601 aacagatgag ccccatgctt ggctctatat cagtttggct agtgcaggtt tgtggattgt
    27661 tttatccttg ttactaagga aaattgcgaa aaaaagttaa gaaaaggagc cagaatggcg
    27721 attgaaaatt atataccaga ttttgctgtg gaagcagtct atgatctgac agtcccaagc
    27781 ctgcaggcgc agggaatcaa ggctgttttg gtcgatttgg ataataccct cattgcttgg
    27841 aacaaccctg atggaacgcc agagatgaag caatggctac atgaccttcg ggacgcgggt
    27901 attggcatta tcgtagtgtc aaataacacc aaaaaacgcg ttcaacgagc agttgagaaa
    27961 tttgggattg attacgttta ctgggccttg aagcccttca catttggtat tgaccgtgct
    28021 atgaaggaat tccactatga caaaaaggaa gtggtcatgg ttggtgacca gctcatgaca
    28081 gatatacgag cagcccaccg tgcagggatt cggtcaattt tagtcaaacc cttggtccaa
    28141 catgactcaa tcaaaacgca gattaaccga actcgtgagc gtcgtgttat gagaaaaatc
    28201 actgaaaagt acggaccgat tacatataaa aaaggaattt aactatggaa gaaattctct
    28261 gtattggttg tggagcaacc attcagacga cagataaggc tggtcttggt tttacccccc
    28321 agtcggcact tgaaaaaggt ttggagactg gcgaagtcta ttgccaacgc tgtttccgtc
    28381 tccgccacta caatgaaatc acagatgtcc agttgacgaa cgatgatttc ctcaagctct
    28441 tgcacgaggt gggagacagt gatgctttag tggtcaatgt cattgatatc tttgatttta
    28501 atggatctgt catcccaggt ttaccacgtt tcgtctcggg caatgatgtc ctcttggtag
    28561 gaaataaaaa agatatcctt cctaagtcag ttaagtctgg taagattagc cagtggctca
    28621 tgaaacgtgc ccatgaagaa ggtcttcgtc cagtcgatgt ggtcctaact tcagcacaaa
    28681 ataaacatgc cattaaggaa gtcattgata agattgaata ctaccgtaag ggccgcgatg
    28741 tctatgtggt cggtgtgacc aacgttggaa aatcaactct aatcaatgct attatccaag
    28801 aaatcacggg tgatcagaat gtcatcacta cttcacgctt tccagggaca accttggaca
    28861 aaatagagat tccgcttgac gacggatctt atatttacga tacgccggga attatccacc
    28921 gccaccagat ggctcactac ttgacggcca aaaacctcaa gtatgtcagt cctaaaaagg
    28981 aaatcaagcc taagacctat cagcttaatc ctgagcaaac cctattttta ggtggtttgg
    29041 gacgctttga ctttatagca ggagaaaagc aaggatttac tgctttcttt gataatgaac
    29101 tcaaactcca tcgtagcaag cttgaaggag ctagtgcttt ctacgataag cacctaggaa
    29161 ctcttctgac accaccaaat agcaaggaaa aagaagattt cccaaggcta gtccagcatg
    29221 tctttaccat taaagataag acagacctag tcatctcagg cctaggctgg attcgtgtaa
    29281 caggcacagc aaaagtcgcc gtctgggcac cagaaggcgt cgccgtcgtc acacgaaaag
    29341 caattattta agcacagaaa ggaaagggtt gtctgaattt gggcgagcaa ggcgagcccc
    29401 atagagaata cttttcgctg tggtgtaagt tggtacaagt gattgtacca actgcggaaa
    29461 atttgagacc ttaggctcaa attttagtca tgaaagtccg aaggactttg ctgacgtccg
    29521 tcaccacttc agaaaagtat aaaaagaaac tcttttaaag aaattatgtc attaacatca
    29581 aaacaacgtg ccttcctcaa cagccaggca cacaccctca aacctatcat ccaaatcggg
    29641 aaaaatggac tcaacgacca aatcaaaacc agcgtccgtc aagctcttga tgcgcgtgaa
    29701 ttaatcaagg ttactctctt acaaaacaca gatgaaaaca tccacgaagt agctgaaatt
    29761 ttggaagaag aaatcggtgt ggatacagtc caaaaaatag gacgcatctt gattttgttt
    29821 aaacaatcta gcaagaaaga aaatcgcaag atttctaaga aagtcaaaga aatctaagat
    29881 cgaaactcca aataactgtt tttatagaga aataaagggg actagcctat gacaatcgaa
    29941 ctattgactc cctttaccaa ggtagagttg gagccagaaa tcaaggagaa aaaacgcaaa
    30001 caagttggga ttttaggggg gaattttaac cctgttcaca atgcccatct tattgttgcg
    30061 gatcaagtac ggcaacagtt gggactggat caagttctgc tcatgcctga ataccaacct
    30121 cctcacgttg ataaaaagga aaccatccct gaacaccatc gtctcaagat gcttgagttg
    30181 gcaattgagg ggattgacgg cctagtcatt gaaactattg agttggagcg caagggtatt
    30241 tcctacactt acgacaccat gaagattttg acagagaaga atccagatac ggattattac
    30301 tttatcatcg gtgccgacat ggttgactat ctgcctaagt ggtaccgaat tgatgaactg
    30361 gttgacatgg ttcagtttgt gggggttcag cgtccacgct acaaggcagg gacttcctat
    30421 ccagttatct gggtggacgt accgctcatg gatatctcgt ccagcatggt gcgtgccttc
    30481 cttgcccaag gtcggaaacc caactttctc ctacctcagc ctgtgctaga ctatatcgag
    30541 aaggaggggc tctactgatg gcctatcaag actatatcaa ctgctcccgt gaggccttgt
    30601 tggaaaaaat ggcagagctt ctacctgaga aacgtctaac ccattgtcta ggtgtggagc
    30661 gtgccgctat ggaattagct cagcgctttg gtgtagatgt tgagaaagca agtctagcag
    30721 gtcttcttca tgactatgct aaaaagttgt cagatcagga atttctagac ttgattgacc
    30781 gttatcagct agatttcgac ctcaaaaact ggggtaataa tgtctggcat ggtatggtcg
    30841 gaatttacaa aattcaggaa gatttggatt tgcatgattc agaaatcctg cgagccattg
    30901 aagtccatac agtcggtgct ggtcagatga cagacctaga taaggtcatc tacgtcgcag
    30961 actatatcga gcacaatcga gcctttcctg gagtagatgt ggcgcgtgag attgcaagtc
    31021 tatcgctcaa taaggcggtg gcctacgaaa cagctcgtac cgtggagtat ctagctcatc
    31081 agggattccc catctatccc caaacccttg aaacctataa cgcctttgtg cactatttga
    31141 aagagaacta aatgaagacg gcttttataa tcattgatgt tcagaatgtt ttagtagaaa
    31201 ctgggttcca gacaaaaagt ctattgggaa aaatttctta tttacaaaac caggctagaa
    31261 gcaagaatat tgaaattatc tatgttcaac atattgagaa ctctgaagct cgaacatcag
    31321 aagattggca gttatctgcg cttttaaatc gaaaacctgc tgaaaaggtc tttcagaaga
    31381 agtataacag tattttcaaa gaaactggct taaaagaata cttggataaa caggggattg
    31441 aaaaattagt tttatgtggt atgcagacag aatattgtgt ggatacctct gtcaaggttg
    31501 cctttgaata tggctatcag cttattgttc cagaaggtgc tgtcacaacc tttgatgggg
    31561 atgacattcc agcagaaacg attaatgaat tttatgagga catttgggag gagcactttg
    31621 cagatgtcct agattacaaa catattttct aaaaagagga ttaaatgaac gaaaaagaat
    31681 tactagaact agtcgtgaaa gcggctgatg agaaacgtgc ggaggatatc ctcgcacttg
    31741 atgtacaaga tttgactagt gtgacggact actttgtcat cactagctca atgaatagcc
    31801 gtcagttgga cgctatcgca gctaatatcc gtgaaaaagt agctcaagca ggctttaaag
    31861 gtagccatgt cgaaggcgat gcagctggag gctgggtctt actggacctc ggtgctgttg
    31921 tcgtgcatat cttttcagaa gaaatgcgtg cccattataa tctagagaag ctatggcatg
    31981 aggcgaattc agtagatatt tcagaagctc ttgcttagaa gatgaactca gttgtagtca
    32041 actgggtttc tttgcttatt ttagaaaaat tgatagaaag gtaaagggct agtggtgttt
    32101 accatggagc tcttagtatc atgattatgg cgacttatga aacctttgcg gctgtctatg
    32161 atgcggtcat ggacgatagt ttatacgaca aatggacgaa tttttctctg cgtcatttgc
    32221 ctaagaccaa ggagagaaag aaactcttgg aactggcttg tgggacagga attcaatcag
    32281 tgcgcttctc tcaggctggt tttgatgtga ctggacttga cttgagtgcg gatatgttga
    32341 agattgcgga gaagagagca acttcagcca agcaaaagat tgcttttata gaaggtaata
    32401 tgctgaattt gtccaaggca gggaaatacg attttgtcac gtgttattcg gactctatct
    32461 gctatatgca ggatgaggtg gaagtagggg acgtctttaa ggacgtgtac aatgcgctga
    32521 atgaagaggg agttttcatc tttgacgtgc actcgaccta ccagacagat gaagtattcc
    32581 ctggctattc ctaccatgaa aatgcggaag atttttccat gctttgggat acatatgagg
    32641 acgaagctcc tcactccatc gtgcatgagc tgactttctt tatcaaggag gctgacggtt
    32701 cctttagtcg ccacgatgaa gtacatgagg agaggaccta tgagatcttg acctatgata
    32761 tcttgctgga acaggctgga tttaagtcct tcaaactcta tgcagacttt gaggataagg
    32821 agccaacaga aactagcacc cgttggtttt ttgtggcgca gaagtaggag attagcatga
    32881 ccataacagg tattatcgcg gagttcaatc cttttcataa tggccataaa tacctgctgg
    32941 atcaggcaga gggactgaaa attgttgcca tgtcagggaa tttcatgcag cgtggagagc
    33001 ctgctattgt ggataagtgg acaaggaccc agatggcgct ggaaaatggc gcagacttgg
    33061 tagtggaatt gcccttttta gtcagtgttc aggcagctga tttctttggt caaggagcta
    33121 tggatatctt ggatcgcttg ggcattgata gtctagtttt tgggacagag gaagttcgag
    33181 attatcagaa aattgctgac ttatacacag agaaaggtgc tgagatggag aaatttgtgg
    33241 aaaatctgcc tgattccctt tcctatcccc agaaaaccca agctatgtgg aaggaatttg
    33301 ctggtcttga tttttcaggt aataccccca atcatgttct tgctctggcc tatgccaagg
    33361 cggttgcagg acgaaatatc aagctgcatc cgattcagcg tcagggggca ggttaccatt
    33421 ctgtgaataa agatgtggac tttgcctcgg cgacagccct ccgtcaacat cagaaggacc
    33481 aagatttctt agaacgtttt atgccttctg ttgccctatt tgagcaggcc agtaaggtga
    33541 tctgggaaga ctattttccc ttgctccgct atcaaatctt gtcaaatccc gacctaacca
    33601 ccatctatca ggtcaatcaa gaaatggctg tgcgcattaa ggaagctatt aaaacagccc
    33661 agtctgtgga agaattggtc gagttagtga ctaccaaacg ttacaccaag gcgcgtgtca
    33721 gacgcctctt gtcctatatc ttggtgcagg ctagagaaag taacttgcca gaagccattc
    33781 atgtccttgg atttactgaa aaaggcaggc aacatctcaa gtctttgaaa ggtcaggtca
    33841 gtctagtcag ccgaattggc aaagaacctt gggatgctat gacccaaaaa gcagaccaga
    33901 tttaccaact aggaaagcca agtatagcag agcaaaattt tggaagagtg ccgattagaa
    33961 tagaaacaaa ctaagtctac cgaaaggtag gctttttgag attttttacg aataatactc
    34021 ttcgaaaatc aaattcaaat cgcgtcaacg tcgccttgcc gtactcaagt acagcctgcg
    34081 gctagtttcc tagtttgctc tttgattttc attgagtata aatagataga aaagaaaatc
    34141 ttgtacaagt tcctgacaat ttctttcttt tcgtgtataa tagtggaaaa gagctaaaac
    34201 gaggtatggt tatggaagca gtcctttact caacattccg aaatcattta aaggactaca
    34261 tgaagaaggt aaatgatgaa tttgagcctt tgacggtggt caataaaaat ccagatgagg
    34321 acattgtagt tctttcaaag agcgaatggg acagtattca ggaaaccctg agaatcgctc
    34381 aaaataagga gttatcagac aaggttttgc gaggaatggc tcaagtccgt gctggaagca
    34441 ttcaggtcca tgtgattgag gagtgatgaa tgctactcaa gtttacagaa gatgcgtggg
    34501 cagattattg ctactggcaa aaccaagata aaaaaacact aaaaagaatc aataaattaa
    34561 tcaaggatat tcaacgcgat ccatttacag gaataggaaa accagagcca ctcaaatatg
    34621 attaccaagg agcctggtca cggcgtattg atgcagaaaa tcgcttgatt tatatgatgg
    34681 atggagatag cgtggctttc ttgtccttta aagatcatta ctaagtctat tgaaaggtag
    34741 gctttttctc aagtctctac taaactacta tttctaaaaa acaagtttat tttggcaaat
    34801 gtgttccaaa ttccccaaaa catattctat tttaggtttg tgaaaatcac ttttttatgg
    34861 tagaatgtaa aagaatgtat gtcattcgga ataacaataa aatgaggtaa aaacatggag
    34921 atcatgtcgc ttgcgattgc tgtttttgcc gtcatcattg gtttagtcat tggatatgtc
    34981 agcatctcag ctaagatgaa atcatctcag gaagctgcag agttgatgct tttaaatgct
    35041 gaacaagaag caactaattt acgtggacaa gctgagcgtg aagcggattt acttgttaat
    35101 gaagccaaac gtgaaagcaa gtctcttaaa aaagaagcac tattggaggc caaagaagaa
    35161 gccagaaaat accgtgaaga agtggacgct gaattcaaat cagaacgtca agaactcaaa
    35221 caaatcgaaa gtcgtttgac agagagagct actagccttg accgtaagga cgacaatttg
    35281 acgagtaaag aacaaacact tgaacaaaaa gaacaaagta tttctgatag agcgaaaaac
    35341 cttgatgcgc gtgaagagca attagaggaa gtcgaaagac aaaaagaagc agaactagag
    35401 cgtattggtg ctctgtctca ggcagaagca cgagatatta tcttggctca gacagaggaa
    35461 aacttgacca gggaaattgc cagtcgcatt cgcgaagctg agcaagaggt caaggaacgt
    35521 tctgacaaaa tggccaagga catcttggtt caagctatgc aacgtatcgc tggtgaatat
    35581 gtagcggagt caacaaactc aacagttcat ctgccagacg atactatgaa gggacgcatt
    35641 attggtcgtg aaggtcgtaa cattcgtacc tttgaaagtt tgacaggggt cgatgtgatt
    35701 atcgacgata caccagaagt ggtgaccttg tcaggatttg atccgattcg tcgtgagatt
    35761 gcccgtatga ctatggaaat gttgctcaaa gatggtcgta tacatccagc tcgtatcgaa
    35821 gagttggttg agaaaaaccg tcaagagatt gacaataaga ttcgtgaata cggtgaggct
    35881 gctgcctatg aaattggtgc gccaaacctt catccagact tgatgaagat tatgggacgt
    35941 ttgcagttcc gtacttcata tggacaaaat gttttgcgcc attcgattga ggttgctaag
    36001 ttggctggta tcatggcgag cgaacttggt gaaaatgcgg ctcttgcccg tcgtgctgga
    36061 ttccttcacg atatcgggaa agccattgac catgaggttg aaggtagcca cgttgaaatc
    36121 ggtatggaat tggcccgtaa gtacaaggaa cccccagttg tggtgaatac gattgctagt
    36181 caccacggag atgttgaagc tgagagcgtg atagcagtta tcgtcgctgc agcagatgcc
    36241 ttgagcgcag cccgtccagg tgctcgtagt gagtctcttg aaagctacat caagcgtctc
    36301 catgatttgg aagaaattgc taacggcttt gaaggagtgc aaactagctt tgcccttcaa
    36361 gcaggacgtg aaattcgtat catggtcaat ccaggaaaaa tcaaggacga caaagtcaca
    36421 atcttggctc acaaagttcg taagaaaatt gaaaacaatc tcgattatcc aggaaatatc
    36481 aaggtaaccg tgattcgcga gcttcgtgca gtagattatg ctaaataaat aagaaagagc
    36541 agttgaaaaa ttactgcttt tttgttacac tagatagaaa gactgtaaag gataatctgg
    36601 ctttttgcca ttattctaga gaaatgttat ttcacagatt gactaaaagg agacacaatg
    36661 gcagaccgag gcttactaat cgttttttct ggtccttcag gggttggaaa aggaacggtt
    36721 agaagagaga tttttgagag ttctgaaaac caatttcaat attctgtatc gatgacgaca
    36781 cgcgcacaac gtcctggaga agtggacggt gttgactatt tcttccgtac tcgtgaagaa
    36841 tttgaagagc tgattcgtca aggacagatg ttggaatacg cagaatatgt cggcaactac
    36901 tatggaactc ctctgaccta tgtcaatgaa accttggaca agggaatcga tgttttcctt
    36961 gaaattgaag ttcagggtgc tcttcaggtc aagaaaaagg ttccagatgc tgtctttatc
    37021 ttcctgacac caccagattt ggatgaattg caagatcgct tggtaggtcg tggaacagat
    37081 agtgcagaag tgattgccca acgaatcgaa aaggccaagg aagaaattgc cctcatgcgt
    37141 gagtatgatt atgcgattgt caacgatcag gtgcccctag ctgctgaacg tgtcaaatgt
    37201 gtgattgaag cagaacactt ctgtgtggat cgtgtcattg gtcactatca ggagatgtta
    37261 ccaaaatctc caactacccg ataaaattta gaaaataggt acaagcaaat gatgttaaaa
    37321 ccctctattg ataccttgct cgacaaggtt ccttcaaaat attcactcgt aatcttggaa
    37381 gcaaaacgtg cccacgaatt ggaagcaggt gccccagcaa ctcaaggttt caagtctgaa
    37441 aaatcaactc ttcgcgcttt agaagaaatc gaatcaggaa acgttacaat tcacccagat
    37501 ccagaaggaa aacgtgaagc agtgcgtcgc cgtatcgaag aagagaaacg ccgcaaagaa
    37561 gaagaagaaa agaaaatcaa agagcaaatt gctaaagaaa aagaagatgg tgaaaaaatt
    37621 taaggttggg gggactcaat cttatttttt ctattgcaag aatgtactga caaggaggag
    37681 gtgagaagat ggccctagct aagattatcg tagatgtgcc cttgatgcag acggaccagc
    37741 cctatagtta caggattccg gaggaatttg agggaatgct ggaagttggg atgcgggttc
    37801 atgtaccttt tggtaagggt aatcgcctga ttcaagggat tgttcttggt ttggagtccc
    37861 aatcagatgg agaagagatg gagcaagatt taaaagatat tgcagaggtg ctggattttt
    37921 ctcctgttct cacgccagaa caactctggc tggctgagga gttacgcaaa tctgtcttct
    37981 cctacaaaat ctctatcctc aaggccatgc ttccaggatt tctgaattct agctatgaca
    38041 agattctcta tcctctggaa ggcttgagtc aggaagaacg agtacgcctg tttggttcag
    38101 aagattcgct agccttttct tcactagacc ttgccaagca agctgaaatg atgcgtttga
    38161 ctagaaaagg cctgcttggt ctggaatatc aggcagtcga tcaaaagaag gtcaagaccc
    38221 agtcttggta tgaggttgac catgctcaat tagaaggtgt tgagatttct acacgtgcca
    38281 agaaaaagtt ggaactgaga gattatctgc tgtctcatcc agagagcgct tccttggcta
    38341 gcttgttaga gtcctactcg cgagagcaag tcaacttctt tgtggatcaa ggtgctgtta
    38401 ccatagtcca aaaggaagtt caacgctcgg ctgcttattt tgaaggaatt gaagcaagta
    38461 gacctttgga gttaaatcca gaacaaagac aggcgcatga tgcggttgtg agttctattg
    38521 gcagttctca acctcccttt ctacttcaag ggattacagg aagtgggaag accgaggttt
    38581 acttgcagat tatccaaggt gccctggata agggcaagac agctattttg ctggtacctg
    38641 agatttcctt gactcctcaa atgaccgagc gttttatagc acgctttggg gacaaggtag
    38701 ccattcttca ctcaggatta tccaatggtg aaaagtatga tgaatggcgc aaggtggagc
    38761 gtggcgatgc ccaagttgtt gttggtgcca gatctgctat ctttgctcct ctgaaaaatc
    38821 tgggtgtcat gattattgat gaagagcatg aagcggctta taagcaggac agcaatcccc
    38881 gttaccatgc cagagaggta gctattttac gggctcagta taatcaagca actctggtac
    38941 ttggatctgc aacgccgagc ttagagagcc gggcgcgtgc tggcaaaggc gtctatcaac
    39001 acttacgtct aacccaacgt gccaatcctt tggctacaat ccctgaggtt caagtgattg
    39061 actttcgaga ctatatcgga caaaatgaga cgtcaaactt tacgcctcct ttgctagagg
    39121 ctatccaaga ccgtctggtt aaaaaagagc aggtggttct catgctcaat cgccgtggtt
    39181 attctagctt tgtcatgtgt cgggagtgtg ggacggtgga tacttgtccc aactgcgata
    39241 tttctctgac cttgcatatg gataccaaga ctatgaactg ccattattgt ggtttctcga
    39301 aggatattcc tcaggtctgt cctaactgta agagccacag tattcgttac tatgggacgg
    39361 gaactcagaa ggcttatgat gagctagcag aactctttcc ccaagctcgc attctgagga
    39421 tggatgtgga tacgactcga aagaaaggca gtcaccaagc cttgcttgac cagtttgggc
    39481 gaggggaagc ggatatttta cttggtactc agatgattgc aaagggtttg gattttccca
    39541 atgttaccct agtcggagtt ctaaatgcgg atacggcctt gaatctgcct gatttccgtt
    39601 cttctgagag aaccttccag ctcttgactc aggtggcagg tcgagcaggt cgggctgaaa
    39661 aggcaggtca agtcttgata cagtcctaca atccgcagca ctatgctatt cgatttgcca
    39721 aggatcaaga ttacgaaggc ttttatgcct atgaaatggg aatcagacga caactcggct
    39781 atccacctta ctatttcacg attggtatta ccctttctca caagaaagaa gaagaggttt
    39841 tcaaacgtgc ctatgaagtc atgaacattt tgcggtcagg cttgtcagag accagtccca
    39901 ttctggggcc aacgccaaaa ccgattgccc gtacccacaa cctctatcat taccagattt
    39961 taattaaata ccgtttagaa gatgagctgg ggccgaccct caaccaggtc ttggccttga
    40021 ctcaagaacg ggaaaatagt gagctccgtc tcagcattga ccatgagccg cagcaatttt
    40081 tataagaagg agaagatatg acaaaactaa tctttatggg gactcccgac ttttcagcaa
    40141 cagtcttaaa aggacttttg acagatgacc gttacgaaat tctagccgtt gtgacccagc
    40201 cagaccgtgc tgttggtcgt aaaaaagtta tccaagaaac cccagtcaag caggctgcca
    40261 aggaagcagg actatctatc taccaacctg aaaaattatc tggaagtcca gagatggaag
    40321 aacttataaa gctaggagca gatggaattg tgactgctgc ttttgggcag tttctcccaa
    40381 gcaaactcct tgatagcatg gactttgctg tcaacgttca tgcctccctc cttcctagac
    40441 accgtggtgg tgcgcctatc cattatgcct tgattcaagg ggatgaggaa gctggtgtga
    40501 ccatcatgga aatggttaag gaaatggatg caggagatat gatttctcgt cgcagcattc
    40561 cgatcacaga tgaggacaat gttggcgcct tgtttgaaaa attggcgcta gttggtcgtg
    40621 atttgctttt ggacactctg cctgcctata ttgctggtga tatcaaacct gaaccgcagg
    40681 atacgagtca ggttaccttc tctccaaata taaagccaga ggaagaaaaa ctggactgga
    40741 acaaaaccaa tcgtcaactc tttaaccaaa ttcgtggaat gaacccctgg cctgttgccc
    40801 atactttcct taagggcgac cgctttaaga tttatgaagc cctaccagta gaaggtcagg
    40861 gaaatccagg tgagattctc tctatcggca agaaagaatt gattgtcgca acggctgaag
    40921 gggctctatc cctcaaacaa gtgcagccag ctggtaagcc taagatggac attgcttcct
    40981 tcctcaacgg agttggacgt acattgactg taggagaacg atttggtgac taaagtagaa
    41041 acggctagaa gtttagctct agcagtgcta gaggatgttt ttgtgaatca agcatattca
    41101 aatattgcct taaataaaca cctcaagggg agtcagctct ctgcagcaga caagggctta
    41161 gtgaccgagc tggtctatgg aacggtagcc cgtaaactga ctctggaatg gtacctatcc
    41221 cactttatcg aagacagaga ccagttagac agctggctct atgtccttct tctcatgagt
    41281 gcctaccaac tccgctattt ggacaagatt ccagatcatg ctgtggtcaa tgaagcagtg
    41341 gaattggcca aactccgtaa aaaaggcagt gaaaaattgg tcaacgctgt ccttcgccgt
    41401 atcttgcgtg aaggctggcc agatattgct agcatcaagc gaaaaaacaa gcgtgactcc
    41461 attgcctatt ctctcccagt ttggctagtt gccaaactca aggaagaata cggagaggag
    41521 agagcaaaag ccatctttga aagcctgtta gtgcgaaaca aagccagtat tcgtgtaaca
    41581 gacctaagtc gaaaagagga aatccaagcc ttgttggagg cgaatgattc ccttttagca
    41641 accactggtc tggttaagga gcaggggcat tttgcagggc ataatttgtt tgcggatgga
    41701 gccattacca tccaagacga gtccagtcag ctggttgctc cgacgcttga tttacaaggt
    41761 gatgagcgag tgcttgatgc ctgtgcggct ccaggtggga aaacagccca tatagcctct
    41821 tatcttacga caggtcaggt tactgctctg gacttgtacg accacaagtt ggatttaatt
    41881 caagaaaatg cccaacgtct gggagttgaa gatcgggttc aaactcaaaa attggatgcc
    41941 agaaaggtgc atgagttttt tgaccaggat tcctttgata agattttggt ggatgctcct
    42001 tgttcaggaa tcggtctttt gcgccgaaaa ccagatatca aatacaataa agaaacggca
    42061 gatttcgcgt ccttgcagga aattcagtta gaaatattag gtagtgtttg tcaaatacta
    42121 ggcaaaggtg gtataataac ttatagcacc tgcactatcg tctcagagga gaattttcaa
    42181 gtcgttaagg cctttttaga gagtcatccc gagttcgagc aggtaaaact agaacatgaa
    42241 tgtaaggata tcatgaaaga cggctgtatc ctcattacac ctgaattgta tggaagtgat
    42301 ggattcttca tcagtcaatt tcgcaagata tcggattagg aaggaactga cacatggaaa
    42361 tttcattatt aacagatgtt ggtcagaaac gaacaaataa ccaagactat gtcaaccact
    42421 atgtcaatag agctggacgt accatgatta ttttagctga tgggatggga ggtcatcgcg
    42481 cagggaatat cgctagtgaa atggcagtca cagacctggg tgtagcttgg gttgataccc
    42541 agatcgatac agtcaatgaa gtgcgtgaat ggttcgccca ttacctagaa attgaaaatc
    42601 aaaagattca ccagcttggt caggatgaag cttacagagg catgggaact actttggaag
    42661 tccttgctat tattgataat caggctatct atgctcatat tggtgattcg cgtatcggct
    42721 tgattcgtgg agaagaatac catcagttga cgagtgatca ttccttggtt aatgaattgc
    42781 tcaaggctgg tcaattgaca ccagaagagg cagaagctca tccgcaaaaa aatattatca
    42841 cccagtctat tgggcaaaaa gatgaaattc agcctgattt tgggacagtt atccttgagt
    42901 caggtgacta tctcttgctc aatagtgacg gcttgaccaa catgatttca ggcagtgaga
    42961 ttcgtgatat tgtaaccagt gatattcctt tagcagataa aacggagaca cttgttcgtt
    43021 ttgctaacaa tgcaggaggt ttagacaaca ttacggttgc ccttgtttct atgaacgagg
    43081 aggatgcaga atgatccaaa tcggcaagat ttttgccgga cgctatcgga ttgtcaaaca
    43141 gattggtcga ggaggcatgg cggatgtcta cctagccaaa gacttaatct tagatgggga
    43201 agaagtggca gtgaaggttc tgaggaccaa ctaccagacg gacccgatag ctgtagctcg
    43261 ttttcagcgt gaagcgagag ctatggcaga tctagaccat cctcatatcg ttcggataac
    43321 agatattggt gaggaagacg gtcaacagta tcttgcgatg gagtatgttg ctggactaga
    43381 cctcaaacgc tatatcaagg aacattatcc tctttctaat gaagaagtag tccgtatcat
    43441 gggacaaatt ctcttggcta tgcgcttggc ccatactcga ggaattgttc acagggactt
    43501 gaaacctcaa aatatccttt tgacaccaga tgggactgcc aaggtcacag actttgggat
    43561 tgctgtagcc tttgcagaga caagtctgac ccagactaac tcgatgttgg gctcagttca
    43621 ttacttgtca ccagagcagg cgcgtggttc taaggcgact gtgcagagtg atatctatgc
    43681 catggggatt attttctatg agatgttgac aggccatatc ccttatgacg gggatagcgc
    43741 ggtgaccatt gccctccagc atttccagaa acccctgccg tccgttattg cagaaaatcc
    43801 atctgtacct caggctttag aaaatgttat tatcaaggca actgctaaaa agttgaccaa
    43861 tcgctaccgc tcggtttcag agatgtatgt ggacttgtct agtagcttgt cctacaatcg
    43921 tagaaatgaa agtaagttaa tctttgatga aacgagcaag gcagatacca agaccttgcc
    43981 gaaggtttct cagagtacct tgacatctat tcctaaggtt caagcgcaga cagaacacaa
    44041 atcaatcaaa aacccaagcc aggctgtgac agaggaaact taccaaccac aagcaccgaa
    44101 aaaacataga tttaagatgc gttacctgat tttgttggcc agccttgtat tggtggcagc
    44161 ttctcttatt tggatactat ccagaactcc tgcaaccatt gccattccag atgtggcagg
    44221 tcagacagtt gcagaggcca aggaaaccct caagaaagcc aattttgaga ttggtgagga
    44281 gaagacagag gctagtgaaa aggtggaaga agggcggatt atccgtacag atcctggcgc
    44341 tggaactggt cgaaaagaag gaacgaaaat caatttggtt gtctcatcag gcaagcaatc
    44401 tttccaaatt agtaattatg tcggtcggaa atcctctgat gtcattgcgg aattaaaaga
    44461 gaaaaaagtt ccagataatt tgattaaaat tgaggaagaa gagtcgaatg agagtgaggc
    44521 tggaacggtc ttgaagcaaa gtctaccaga aggtacgacc tatgacttga gcaaggcaac
    44581 tcaaattgtt ttgacagtag ctaaaaaagc tacgacgatt caattaggga actatattgg
    44641 acggaactct acagaagtaa tctcagaact caagcagaag aaggttcctg agaatttgat
    44701 taagatagag gaagaagagt ccagcgaaag cgaaccagga acgattatga aacaaagtcc
    44761 aggtgccgga acgacttatg atgtgagtaa acctactcaa attgtcttga cagtagctaa
    44821 aaaagttaca agtgttgcca tgccgagtta cattggttcc agcttggagt ttactaagaa
    44881 caatttgatt caaattgttg ggattaagga agctaatata gaagttgtag aagtgacgac
    44941 agcgcctgca ggtagtgcag aaggcatggt tgttgaacaa agtcctagag caggtgaaaa
    45001 ggtagacctc aataagacta gagtcaagat ttcaatctac aaacctaaaa caacttcagc
    45061 tactccttaa aagcagatgg ataatcaaaa tgagtaatca atctttgtca tgatttcatg
    45121 gcaaagattt tttttgagtc cagatttgtg atagaataga gggagttgat aaaaggagga
    45181 aagcatggaa gaatcaaaag aattaaatgc cgtcattgat gtgattatgc tagcggggac
    45241 tattctcctt aaaagtggct cagaaatcca tcgtgtagaa gataccatga ttcgaatcgc
    45301 gcattcgcag gggattgtgg attgcaatgt ccttgccatg cctgccgcta tctttttctc
    45361 tattgaaaat accaatattt cgcgcatgaa gcgcgtgacc tcctcttctt ataacatcga
    45421 aaaagtctgc gatgtgaacc agatttctcg tcagctagtt ggggggcaga ttgacttaga
    45481 aacagccttt aagcaattga cggccttgca agctcaaccc cttccctata ctaagttgca
    45541 ggtaactctg gctgcgacct ttagtgctcc tttcttttca gttatgttta gcggaaatat
    45601 ctacgacgca cttggggcag gagtggcgac cttatttggt tttgcctttt ccctctatgt
    45661 ggaaaaattt atccgaattc cctttgtgac agcctttgct ggagcctttg tctttgggat
    45721 aattgcccag ttttgggctc gctacacagg ttttccttca acggcagatt tgattatagc
    45781 tggtgcggtc atgccgtttg taccaggtat tgccttgacc aatgcggtcc gtgatattat
    45841 gaccaaccac ataaactctg gtatgagtaa gatgtttgaa tccctgctca ttaccctcgc
    45901 tttaggggca ggaacttctg tcgccttggt attgatgaac taatatgaca ctaacaacct
    45961 ttttattaca agcagtagca agttttcttg ccattatcac ttttttaatc gtactcaatg
    46021 tgcaacggtc tatgctctta cctggaggga ttttgggcat gactgtctgg ctaatctatc
    46081 tcttgctcaa ggaaccgacc aatgtcattg tagctacctt cattgcagcc attattggtt
    46141 cttgtgtcag ccagatttta agtattcttt ataagacacc tgctgtggtc tttatcttgg
    46201 ccattttggc accgctggtt ccaggttatc tctcctaccg aacaactgcc ttttttgtga
    46261 caggggacta taataaagca ctggcaagtg cgaccttggt tgtcatgttg gctctggtaa
    46321 tctctattgg aatggctagc ggaacagtga ttctcagact ctatcattat ataaaaacac
    46381 atcgagtatc gtagacttta cagaaataaa agaattttct gaaaaatgag acaaatagat
    46441 tgacaacgct ttctatatgt gcgagaatat cgaacttatg aagaaattgc ggctgatttt
    46501 ggtatccacg aaagcaactt aatccgtcgg agccaatggg ttgaagtaac tcttgttcaa
    46561 agtggtgtta cgatttcaaa aactcatctt agtgctgaga atacggtgat tgtggatgca
    46621 acagaggtaa aaataaatcg tcctaaaaaa atcaactagc caattattct ggtaaaatag
    46681 aaatgtcatt ctatggaacc tcaagcgatt gtcaccagcc aagaaagaat tgtttctttg
    46741 aatattgcgg tgaactattg ccacgatatg aagttgttca aaatgagtcg cagaaatatc
    46801 ggacaagctg gtaaaatctt ggctgacagt ggttatcaag ggcccatgaa gatatatcct
    46861 caagcacaaa ctccacgtaa atccagcaac ctcaagccgc taatagctga agataaagct
    46921 tataaccatg cgctatccaa ggagagaagc aaggttgaga acatctttac caaagtaaaa
    46981 acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg
    47041 aatttgattg ttggtattat caatcatgaa ctaggattct agttttgcag gaagtctact
    47101 attttcctta ttgtctgtaa gtctactgac cttgttgttt atcccagtca tggtttctag
    47161 ttcgggctca gagtttcaaa gtggatggca agagcatcaa ttgattgctg agaaggttag
    47221 taaaacactt gacaagacat ttgataagga tgtcagagaa attccgacca gtcagtttta
    47281 tcaaaaattt gtagatgaga tgggaaggac ttactcagga aatttgatcc tccaggagct
    47341 gataactgtg aatggagctt ataaagctac ttatatcggt gaactctcta gcaaccaatc
    47401 attctttaaa atgatgacca ataagaggct tgatttggtg aatcaagtct tttttctctc
    47461 ttttactgcc atttgtgata aaatagtata gaacgatttt ttacatgaat gataaaacag
    47521 aggtaaatat gacaatcggt attgataaga ttggttttgc gaccagtcaa tatgtcttga
    47581 aattacaaga cttagcagaa gcgaggggaa ttgaccctga aaaattaagt aaaggactct
    47641 tactcaagga attgagtatt gcgcccctaa ctgaggacat cgtgaccttg gcggccagtg
    47701 ctagtgactc tattttaact gagcaagaaa gacaagaagt tgacatggtc attgtggcta
    47761 ccgagtcagg aattgaccag agtaaggctg cggccgtctt tgtgcatggc ttgctgggca
    47821 tccagccctt tgctcgtagt ttcgagatta aagaagcctg ctatggggcg acagctgccc
    47881 tccattatgc caaattgcat gtggaaaatt ctccggagtc caaggtattg gtcattgcca
    47941 gtgatattgc caaatatggt attgaaactc cgggagaacc aactcaaggt gctggaagtg
    48001 tagctatgtt gattacacaa aatccacgca tgatggcctt taataatgat aatgtagctc
    48061 agacccgtga catcatggat ttctggcgac caaattactc gacaactcct tatgtaaatg
    48121 gtgtctattc tacccaacaa tacttggata gtttgaaaac gacttggctt gaatatcaaa
    48181 aacgctacca gcttactttg gatgattttg ctgctgtttg tttccacttg ccttatccta
    48241 aattagcgct aaaaggcttg aaaaaaatca tggataagag cctgcctcaa gagaaaaaag
    48301 acctcttaca aaagcatttt gaccagtcta ttctctacag tcaaaaggtg gggaatatct
    48361 acacaggttc acttttcctt ggacttttgt ctctcttgga aaatacagat agcttgaaag
    48421 ctggggataa aatcgccctt tatagttacg gaagtggagc tgtggctgag ttcttcagtg
    48481 gtgaattggt tgaaggatat gaagcttatt tggataaaga ccgcttgaac aagctcaacc
    48541 aacgaactgc cctatccgtt gcagactatg aaaaggtctt ttttgaggaa gtaaacttgg
    48601 atgaaacaaa ctctgcccag tttgctggct atgaaaatca agattttgcc ttggttgaaa
    48661 ttcttgacca ccaacgccgt tatagcaagg ttgaaaaata atgaagataa gttggaatgg
    48721 attttctaaa aaatcatacc aagagcgcct cgagctgcta aaagctcagg cgctccttag
    48781 tcctgagaga caagctagtc tggagaagga tgaacagatg agtgtgactg tggcagacca
    48841 gctgagtgag aatgtggtgg gaactttttc tctgccttat tcgctggttc cggaggtact
    48901 tgtcaacggt caggaataca ccgttcccta tgtgacagaa gaaccctctg tggttgcggc
    48961 ggccagctat gccagcaaaa tcatcaagcg tgcaggtggt tttactgcac aagtccatca
    49021 gcgccagatg attgggcagg tagcccttta tcaagttgct aatcctaaac tagcgcaaga
    49081 gaagattgcc agcaagaaag cggagctctt ggagcttgcc aatcaagcct atccttctat
    49141 cgttaaacgt gggggtgggg cgcgtgatct gcatgtcgag cagataaaag gcgaaccaga
    49201 ctttctcgtt gtttatattc atgtcgatac ccaggaagcc atgggtgcca atatgctcaa
    49261 caccatgctg gaagccttga aaccagtctt agaagaactc agtcagggac agagtctcat
    49321 gggaatcctg tccaactacg cgactgattc tctggtgact gcaagctgtc gcatcgcctt
    49381 tcgctacttg agccgccaaa aggatcaagg acgagagatt gcggagaaaa ttgcgttggc
    49441 tagtcagttt gcgcaggctg atccttaccg agctgctact cataataaag gaatttttaa
    49501 tggtattgat gcgattttga ttgccactgg taatgactgg cgtgccatcg aagctggggc
    49561 ccatgccttt gccagtcgag atggacgcta tcaaggtctt agctgctgga cgctggacct
    49621 tgaaagagaa gaattggtcg gtgagatgac cctgcccatg cctgtagcga ctaagggtgg
    49681 ctctatcggc ctcaacccac gtgtagctct cagtcatgat ctactaggaa atccttctgc
    49741 cagagaatta gcccagatta tcgtgtccat cggtcttgct caaaattttg cagccctcaa
    49801 agccttggta agtacgggca tccagcaagg ccacatgaaa ctacaggcca aatccctagc
    49861 tctcctagct ggggctagtg aatctgaagt tgctccccta gtagagcgcc tcatctcaga
    49921 taaaaccttt aacctagaga cagcccagcg ctatctcgaa aatttaagat cataaaaact
    49981 cagacgaatc ggtctgagtt ttcttgtgtt taaatacttt ttcctggtaa tagcgtaact
    50041 ggtaagaagt aaccagttgt ggcgacttcc ttgccttcaa tcttttgcaa gagaagatca
    50101 atagtgagac aagcaatctc ttccaaaggt tgcttgatag tagccaattg agggtagtaa
    50161 ttttcgataa agtaggtccc atcatagccg atgaccttga gctcttttgg gacagaaatg
    50221 cccaattctt gagcgatttt aatgaccaga atagctgtca aatcatccga agcaaaaatg
    50281 gcatctggtt tttcccgggt caagatattc ttgatttcca tttcttttct gacgggagaa
    50341 aagtcactgg aaacattgat aataggagct tttgggagta cggatgcaaa accagcgtgg
    50401 cgcagtccgg ttggcgaatt ggaattgtca ttccctgtaa tcatgatgat agactgggca
    50461 cctgtcttga ccaaggtttg ggcagcaaga accccaccag catagttgtc agaggagaca
    50521 acagggatgt ctggcgatag gtttcggtca aaggaaataa tcggcgctgt cacacgattg
    50581 tagtcttcga ttcctaggtt gtgactacca gaaatgatgc cgtctacctg attggcttcc
    50641 aacatttcga tgtattcgcg ttccttctca gaatcatgtt cactgttgca gatgatggtc
    50701 ttgtaaccat ttttgaagag ttggtgttcc aatttatcaa tcaattctgc atagaaaaca
    50761 ttggaaatat tggggaaaat caagccgatt aacttagctg attttccttg cagactacga
    50821 gccaggttgt tgggtttata gcccaattct ctcatggctt cattgacttt ttggatggtt
    50881 ttctcagata gatacccttt tttattgata acccgagaaa cggtagtagg actgacgcct
    50941 gcaagtttgg cgacatcagt tagttttgcg accataatct aattcatagt aagttccagt
    51001 tgggtttcca gatttgatca ggataccatt ttggtccgca tgtgggaaga cacgaccaga
    51061 aaatactttt tctcctttat tgatgaaaat ttcaaagaca gagttatcga tgaagattgt
    51121 agcagtagta gcctgattct cgatagggca agaacgagtt gtcccaaatt cttgggcata
    51181 ctgttctcca gcctggctac gatccactgt cacttgaccg tttacaaggt caaagttgat
    51241 tgaaagtccc ttaccttctt tatcagcaag taagacaatc tcgctctggc tattagcttc
    51301 caagttgagt tcaagttcgt aagtgttctt ggtttgggaa cggtttgaga aggcttcttc
    51361 agaagcacga aggtccttaa tagcagcgac tggatactgg tagagcttgt cgtctttgat
    51421 agtgagttcc ttgaccaaag agaaggttcc ttggtgatca aaacagtcag atgggtaaga
    51481 aacatctggc aaaccaagcc agctaactgc tagagcacgc ccatcaggag cgttgaaggc
    51541 ttgagttgca taggcttcga aaccgtaatc catgttttga agttgagaca catctaccat
    51601 tttggcattt ttagggtcaa aggaagcccc aatcttatac atatttggaa agatattatc
    51661 gtagtctaga actttcttat ccaatccttg tggacagtag agaaggacag gctgttcctc
    51721 tacaaagacc agattaggac attccatcat gtaggcagta cggtcgttag caaagtcaag
    51781 gtcgccaact gcttgccagt ttgtgtagtc gttattgaca gccttgtaga gacgaacgaa
    51841 accttttttc tccaagtctt gtccgccgac aatggcataa tattgaccct gaaagttaaa
    51901 aatttgtgga tcgcggaagt ggtcagtaga gtctgctggc tggtcaatca agatcttgtc
    51961 aatctttgta atcttaccct ccttgtccat caaagcaccg atctggtatg ggtgacggat
    52021 ccagttttta tcgcgaacat ttcctgtata aaataggaat aagttatcgc caaattgcat
    52081 ggcagaacca gagtaggcac cgtggctatc taatggagta tctggtaaaa ctttgattcc
    52141 agtttcttta aagtgaatca aatcatcact ttctagctgt gcccaagatt ttaaaccgtg
    52201 ggctgcacca aaaggaaaat tctggtaaaa gaggatccac ttgccatcaa agtaagaaaa
    52261 gccatttggg tcgttgagaa gtcctgtttt tggctcaaca tggtaatgag tatgccatgg
    52321 agattgtgcc atattttcct ttatatgttg aatttcttct tgcgtccaat cttgataaag
    52381 tctgtaacga cgctcagttg tccattccat tcattcctcc aaaaatctta tcacttttaa
    52441 tagtaactgt tttcgataaa aaatgcaagc cttttatatt aaaaaagagg aaaaactgtc
    52501 aaacgattat cataaaataa atacaggaaa tcaatcaaat ttttacgaaa atgtgaaaga
    52561 taatgaaata aaagactttt taaccaaggt ttcaaactta tttttcaaga aattcctgat
    52621 gaaacagtca aaaacaatca atctaaagct tgcccactaa gtagatagaa tattttttat
    52681 gcaaaacgct tgacatattt ttaaaacatg ataaaataat agtcgtaagg gcgaataaaa
    52741 tcgctttcaa acaagaacaa aatgttatat aaggagattt ttgcaaatga acaatcagga
    52801 aattgcaaaa aaagtcatcg atgccttggg cggacgtgaa aatgtcaata gtgttgccca
    52861 ctgtgcgact cgtctacgtg tcatggtcaa agatgaagag aaaatcaata aagaagtgat
    52921 tgagaacttg gaaaaagttc aaggtgcttt ctttaactca gggcaatacc aaattatctt
    52981 tggtacaggt acagttaaca aaatgtacga tgaagttgtt gtacttggct taccaacatc
    53041 atctaaggat gacatgaaag cagaagttgc taaacaaggg aactggttcc aacgtgctat
    53101 ccgtactttc ggtgatgttt tcgttccaat catcccagtt atcgtagcga caggtctctt
    53161 catgggtgtg cgtggtcttt tcaacgctct tgaaatgcca cttccaggtg actttgcaac
    53221 ttacacacaa atcttgacag atacagcctt catcatcttg ccaggtttgg ttgtgtggtc
    53281 aaccttccgt gtatttggtg gaaatcctgc cgttggtatc gttcttggta tgatgcttgt
    53341 ctctggctca cttccaaacg cttgggcagt tgctcaaggt ggtgaagtaa cagcgatgaa
    53401 cttctttggt ttcatccctg ttgttggttt gcaaggttcc attcttccag ccttcatcat
    53461 cggggttgtc ggagctaaat ttgaaaaagc tgtccgcaag gttgttccag atgtcattga
    53521 cctcttggta acaccattcg tgacactttt ggtcatgtct atccttggac tctttatcat
    53581 tggaccagtt ttccacgttg ttgaaaacta catccttatt gctacaaaag cgattcttag
    53641 catgccattt ggtcttggtg gtttcttgat tggtggggtt caccaattga tcgtcgtgtc
    53701 aggtgtgcac cacatcttca acttgcttga agtgcaatta cttgctgctg accatgctaa
    53761 cccattcaac gctatcatca cagctgctat gacagctcaa ggtgctgcta ctgttgcggt
    53821 tggtgttaaa acaaaaaatc caaaactgaa aacacttgct ttcccggctg ctctttctgc
    53881 cttcctaggt attacagagc ctgctatctt cggggtgaac ttgcgcttcc gtaaaccatt
    53941 cttcctttca ttgattgctg gtgcaatcgg tggtggattg gcttctatcc ttggacttgc
    54001 tggtactggt aatggtatca ccatcatccc tggtacaatg ctttatgttg gtaacggaca
    54061 acttccacaa taccttctta tggtagctgt atcatttgcc cttggttttg ctcttactta
    54121 catgtttggt tacgaagatg aagtagacgc aactgcagct gcaaaacaag ctgaagtggc
    54181 tgaagaaaaa gaagaagttg cgccagcagc tcttcaaaat gaaacacttg taactcctat
    54241 cgttggtgat gttgtcgctc ttgctgatgt caatgaccca gtcttctcaa gtggagctat
    54301 gggacaaggt atcgctgtga aaccaagcca aggcgtggtc tatgcaccag ctgatgctga
    54361 agtttcaatt gcctttccaa cagggcacgc ttttggtttg aaaacaagaa atggtgctga
    54421 agttttgatt cacgttggta ttgacactgt atctatgaac ggtgacggtt ttgaagcaaa
    54481 agttgctcaa ggtaataagg tgaaagctgg cgatgttctt ggaacatttg actcaaacaa
    54541 aatcgctgca gctggacttg atgatacaac aatggttatc gttacaaata cagctgacta
    54601 cgcttcagta gctccagtcg caacaggttc agttgcgaag ggggatgctg tgatcgaagt
    54661 gaaaatctaa tcaatcctct ctaatgtgaa aacgaacaaa tgacatgttt gttcgttttt
    54721 attagatagt aagatttaca gaggaaaatc taaaaaatag agacatttag actttcgaag
    54781 tatgctataa taaagaaaat aaaaacaaga ggtttatcat gacaaaatta tatggaagct
    54841 tggaagcggg cggtacaaag tttgtctgtg ctgtcggtga tgaaaacttt aacgttgtag
    54901 aaaaaacaca atttccaaca acaactccaa tcgaaacaat cgataaaacc attgagttct
    54961 tctcaaaatt cgataacctt gctggtcttg cagttggttc atttgggccg attgatattg
    55021 acaaaaactc aaaaacttat ggctttatca cgacgactcc aaaaccaaac tgggcaaatg
    55081 tggacttgct tggtgccctt cgtcgcgccc tcaacgtgcc aatgtacttc acaacagacg
    55141 taaacagctc tgcttacggt gaagtggttg cccgtaacaa tgctggtggt cgtatcgaaa
    55201 acttggttta ctacacaatc ggtacaggta tcggtgcagg cgtcatccaa cgtggtgagt
    55261 ttatcggtgg tgtgggtcac cctgaaatgg gtcattatta tgttgctaga cacccaatgg
    55321 atattgaaaa agagtttaag ggtgtttgtc ctttccataa gggatgtctg gaaggctatg
    55381 cagctggtcc aagtttggaa gctcgtacag gtgtacgtgg ggaaaatatt gaactcaaca
    55441 accctgtttg ggatgttcaa gcctactata tcgctcaagc tgcggttaat gcgacagtga
    55501 ctttccgccc agacgtgatt gtctttggtg gaggggtcat ggctcaacaa catatgctgg
    55561 accgtgtccg tgagaaattt acatctcttc ttaatggtta cctaccagta ccagatgtgc
    55621 gtgactatat cgtgacgcca gcagtcgcag gaaatggttc tgccacactt gggaactttg
    55681 ttcttgcaaa agaagtttca aaataaagca caaaatccgc ttgggaaacc aaacggattt
    55741 tttacgtgtc aaagcatttg ccagaaaaag tcaataatat aggtcagacc gtaggtataa
    55801 accacgaggg taaagggttt ggtcagaatg atgatggtca tgtagcgctt gaaactcatc
    55861 ttggtcaggg cagccagcat acagagaaag tcagctgggc taatgggcca aatcatcata
    55921 aaaataaaga agcggtcaaa acgattgccc ttatctagcc agccgatgta cttgtcgtag
    55981 gtgcgcttgc tgacgacaga ctggacaaag gcagctccgt ataggcgcac tagataaaag
    56041 ataatggcac agccaatcac gatgccgata tagttgtaga tagtcccgat gatgtgcccg
    56101 tagataaaga ccccagccac cgaggtcaag gcccctggaa tgatagggac gacagtctgt
    56161 aaaatctgta aaaagataaa gagaggtgga ccccagatgc ctgcctgctg gataaaggca
    56221 gagagggttt ccttggattg taaaatccca gcctgataag cccaaataca gaaaatcaaa
    56281 ctcccaaccc caccgacaat cgatgagata ttgataactc gctgcagaag gggagaaaca
    56341 gctttcattt gtttatcctg tgacatgtaa actcctcata gatagtatat ttctactata
    56401 ccatattttg gaggagaaag ggggaatgag tcttttttga taaggaatag aaagtaaata
    56461 gcccttcgag acttagaata ggtctgtcaa ctaaaggtta tatgcattct aggtttcgaa
    56521 taatcgcaat tccatgaatt taaaagcatt ctaagtttcg aatagcttat ctgagataat
    56581 tttgaggcat tcgcgctttc gaatagtcat tttccctaaa gtttagatgt attctgaagc
    56641 tagaaagact aaaatctaaa agtagtaaga gtctctctct gatggacgta atttatggct
    56701 agtatgaatc ctttgaattg ttagttaatt ttaatattaa tcagttctga aataattact
    56761 aaatatagtt agatggtgaa ttaattattg ctaaatttca agttcaagtt agtcatccag
    56821 aagtcttctc tgggggactt gtagttcaag cattttttag gatagttgtt aatccacttt
    56881 tcgatgaatg cgacttcctt tgtagtcgtt ttcttagttt cctgaggtaa ccatctatga
    56941 atgagcctgt tgtgattttc attagatcct atagtgatgt gcataataga tatagcagat
    57001 tgaaactaga atagtataca tctacttcta aaacattgtt agaaatcaat ttgactgtcc
    57061 tgatcaattt gtcctgttct tatttcattt tactatataa tccttagaaa acatatcgga
    57121 caagcggttg aattctgttc cgtccattag tagataaagg attactcctt cttgaaatga
    57181 cagatgaact tgtttcttat aaaaatgttg tctgaaacta ttagcctttt tccagaagtt
    57241 ttagaggaag aaaacttctg gaaaaaggag ttactcaagt aacaattcag gattaaaaat
    57301 agacagttga ggagcggaag gtataaatta agtttgctgc tgtataatgg atttatcact
    57361 aatactcttc gaaaatctct tcaaaccacg tcagcttcgc cttgccgtac gtatagttac
    57421 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttt
    57481 tatctgcaac ctcaaagctg tactttgagc agtctacggc tagcttccta gtttgctctt
    57541 tgattttcat tgagtataaa agtgctccag gacatatttt acacagcaat agtcttctaa
    57601 aaatggacaa aaaacattgt aaaggctatc aaaaaggagt ataatgagtg caagaaattt
    57661 cggaggtgaa agatgctaga agtaagaagt ctagagaaaa gttttggatc caagcaagtt
    57721 ttgtttggta ttgactttca agcgcgacca ggtcgtattt tgggactagt cggaaaaaat
    57781 ggtgctggaa aaacaacgat tttccatagt attttaaaat tcctagaata tcagggagaa
    57841 atcggtctgg atggtcagga tattcgtcag gagacctatg ctcggattgg ttatctgcct
    57901 gaagaacgca gtctcatgcc taaattgaca gttcttgaac aagttcgcta cttggcgact
    57961 ctaaaaggca tggatgccaa agaagtcaaa gaaaaactcc ctcaatggat gaagaggttg
    58021 gaagtaaaag gaaagctgac agataaaatc aagagtctgt caaaaggaaa tcagcagaag
    58081 attcagctca ttattactct gattcatgaa ccagacctga ttatcttgga tgagcctttt
    58141 agtggattgg acccagttaa tacagaattg ctcaaacaag tcatttttca ggaaaaagag
    58201 cgcggagcaa ccattatctt ttctgaccat gtcatgacca atgttgagga actttgtgac
    58261 gatattctga tgatccgaga tggccgtgtg gtcttgcacg gaccagttca ggatgtccgc
    58321 aatcaatacg ggaaaacgcg tctctttgtt tcaagtgaac gaagcaagga agaattggaa
    58381 aatcttcctc atgtcaaaca ggtgagcttg accaaacaag gcagttggaa attgattttg
    58441 gaggatgaga gcgctggaag ggaactcttc ccaatcttga ctcaaggtca atatatcgca
    58501 acatttgacc aacaagcgcc aactatcgat gaaatcttta aactagaatc aggagtggaa
    58561 gtatgagaaa tatgtgggtt gtaatcaagg aaacctatct tcgacatgtc gagtcatgga
    58621 gtttcttctt tatggtgatt tcgccgttcc tctttttagg aatctctgta ggaattgggc
    58681 atctccaagg ttcttctatg actaaaaata ataaagtggc agtagtgaca acagtgccat
    58741 ctgtagcaga aggactgaag aatgtaaatg gtgttaactt cgactataaa gatgaagcaa
    58801 gtgccaaaga agcaattaaa gaagaaaaat taaaaggtta tttgaccatt gatcaagaag
    58861 atagtgttct aaaggcagtt tatcatggcg aaacatcgct tgaaaatgga attaaatttg
    58921 aggttacagg tacactcaat gaactgcaaa atcagcttaa tcgttcaact gcttccttgt
    58981 ctcaagagca ggaaaaacgc ttagcgcaga caattcaatt cacagaaaag attgatgaag
    59041 tcaaggaaaa taaaaagttt attcaaacaa ttgcagcagg tgccttagga ttctttcttt
    59101 atatgattct gattacctat gcgggtgtaa cagctcagga agttgccagt gaaaaaggca
    59161 ccaaaattat ggaagtcgtt ttttctagca taagggcaag tcactatttc tatgcgcgga
    59221 tgatggctct gtttctagtg attttaacgc atattgggat ctatgttgta ggtggtctgg
    59281 ctgccgtttt gctctttaaa gatttgccat tcttggctca gtctggtatt ttggatcact
    59341 tgggagatgc tatctcactg aataccttgc tctttatttt gatcagtctt ttcatgtacg
    59401 tagtcttggc agccttccta ggatctatgg tttctcgtcc tgaggactca gggaaagcct
    59461 tgtcgccttt gatgattttg attatgggtg gtttttttgg agtgacagct ctaggtgcag
    59521 ctggtgacaa tctcctcttg aagattggtt cttatattcc ctttatttcg accttcttta
    59581 tgccgtttcg aacgattaat gactatgcgg ggggagcaga agcatggatt tcacttgcta
    59641 ttacagtgat ttttgcggtg gtagcaacag gatttatcgg acgcatgtat gctagtctcg
    59701 ttcttcaaac ggatgattta gggatttgga aaacctttaa acgtgcctta tcttataaat
    59761 agaagagcct tgcgaaagcg aggtttttaa aggtgaaaag ggtggaatca cgaacctaat
    59821 tatgtacaca ttatgtaaac aagttgcttg aaaactcaat tgtatagtga actgaatctg
    59881 gaataggata atattacttc taaaacattc ttacaaattg atttgaattc caaaatccca
    59941 tcgttccgtt cttatttcat tttgcgatat agtgaaagga aataagtcag ctcacaaaaa
    60001 atgcatatta ccaaggttct tatgaactgc ccccaaaaag ttagacagaa aaaatctaac
    60061 ttttggagtc agtacatttt aatacttgat actatgcgtt ttctaatttt aaagactttt
    60121 tgcctggtct cttttgttct atgagtatgt tacatatcta ggtaaaaatt atttaaagca
    60181 aattaacctt atttctcaag atgtagtagg ttccgagata aaagatagct atgaatatga
    60241 gttcttcaac aatggctata cctgctccca tatagaaatg gtcattgagt cctaccagtg
    60301 aattgacata gaaattagaa ctaagattga agaaaagttc aataaatcca atgacgattt
    60361 ggataccaat gtagactgca acagcgagtg ctgtacggta ttcattgaaa agctgtccaa
    60421 tggaaatagc caggtagatg cagaggattc ctgaaatggt atttagtagg aaggatatac
    60481 ctgtaagaaa gatctgaggg agatgtgttt ctacaaatgt aatcacataa gaaagaggaa
    60541 tccattctgg agctgttaaa gccagaataa taacagcact tagagccaat acagcggtgc
    60601 taatcaatga ccagataaag gcaccgatta gtttggctgt gatgatatgg tgttcagaaa
    60661 ctggcaaggt caaagtcaga tagccttgtc ggtcgtagac actacctttg aagcgtttaa
    60721 taatcaagaa aatggttgaa atcccaagtg taagcatcaa gccaccaaag actgtagcta
    60781 gaaaaagtag catagtagcc tgactttctt ggtaaggtag atttttaaag ccttgtgtct
    60841 gtattccgat gagggcagaa aggactagca cggctgcgta gagggctaaa taccacttgt
    60901 taacattttt aaattcgtag cgaactaaat tccaaaacat aaataatctc ctttgcttag
    60961 gccttaaatt cctgacggaa gagttggtca atggattcac ctgactcgta gcgaatatca
    61021 tctacatttc cttgacggac gacttttccg tcttttagga agacaatttc atccaagatt
    61081 ggctcgatat cagaaatcaa gtgggtagaa atcaaaacgg tagaagttgg tgagtagttg
    61141 ttgataatgg tattgaggat ataagcacgg gctgctggat ccaccccacc aatgggttca
    61201 tccaaaacat agagacgagc atcacggctc ataaccaaaa tcagttgaac cttttctttg
    61261 tttccttttg atagtttctt gagacgacta ttttcatcaa tgcccaggtc tgcaagtaga
    61321 tgatgggcgc gttcaagatt gaaatcttta tagaaggtct tgaagtaggt tagggcttct
    61381 ttgaccttca tttgctcatt gagataggtc gtatcaggca aataagctac aacggccttg
    61441 gttgctggat ttgggtccat gtcgttgatg aggacacgtc cttgatctgg ttgtaagagg
    61501 ccattaatta gtttaatcag ggttgttttt cctgagccgt ttggcccaag aaggccgaca
    61561 atttttccag ctggaatgtc aagagaaaca ttttcaaggg ctggtgttgc tccatatgat
    61621 ttggatacat tttcaaatgc tagtaatgac ataggcttaa actcctttaa tataatcact
    61681 gactacgcct ggtagttctt ctttttcata gccaaaatgg gtcatggagg aaacgaagtg
    61741 ttccaattct tcttctgata attgtttgcg tgactgggcg attagctcct tatccttagt
    61801 cacaaatcgt ccagttgttc gcttgctgta gacaaatcct tctcgttcaa ggtctgataa
    61861 ggctctttgg atggtattgg gattgacacc agcctcgcta gctagctccc taacggttgg
    61921 aagttgttga ttgggttcca gtttatggga aacaatctga agcttgattt tttccataat
    61981 ctgtaaatag atgggttttt tgttgtcaaa tgtccaggac atcttagtct cctttctttt
    62041 acccttttgt cttaattaaa taatacaaca aaacaaaaaa cttgtcaagc aaaaagaaga
    62101 attgttttgg gaatcgctta aaaaatggta taatgaaaag aaaacgataa ggagggaaag
    62161 gatgcgttgt ccaaaatgtg gggctaccaa gtcaagtgtt atcgatagtc gccaagcaga
    62221 agaagggaac accattcgta gaagacgaga gtgcgacgag tgccaacacc gttttacaac
    62281 ctacgaacga gtagaagaaa gaaccttagt ggttgttaaa aaagatggca cacgggaaca
    62341 attctccaga gataaaatct ttaatgggat tatccgctca gcccagaaac gtcctgtgtc
    62401 aagtgatgaa atcaacatgg tagtcaatcg tatcgaacag aaactccgtg gtcgaaatga
    62461 aaatgaaatt caaagtgagg acattggttc actcgtcatg gaggagttgg ctgaattgga
    62521 cgagattacc tatgtacgtt ttgctagtgt ctatcgtagt tttaaggatg tcagtgagtt
    62581 agagagcttg ctccaacaaa tcacccagtc ctctaaaaag aaaaaggaaa gataaatgaa
    62641 gccaattgac cgtttttctt atctaaagaa taatcgggtg tcgcaagata cctcatctct
    62701 ggtacagtgc tacctcccga ttatcggtca ggaggcactg agcctttatc tttatacaat
    62761 cagtttttgg gataatggta gaaaggaata tcttttttca agtatcctca atcatctcaa
    62821 ctttgggatg gatagactga taaaatcatt gaaaatctta tctgctttta atctcttgac
    62881 cctctatcaa aagggggatg tttatcagct agccctccat gctcctctat ctagtcaaga
    62941 cttcttggag catcctgttt atcgcagact cttagagaaa aagattggcg actctgctgt
    63001 ggaggatttg aaagttgaaa gtgctgatgg tgaagaaata cctgtctcac tcaatcaagt
    63061 ctttccagaa ttggcagaac taggcagtca agaagacctt ggtctcaaga agaaagtggc
    63121 caatgatttt gacttggaac attttcgcca gctgatggct cgagatggac ttcgttttgc
    63181 ggatgagcag tccgatgtct taaacctctt tgctattgcc gaggagaaga aatggacttg
    63241 gtttgaaacc tatcaattgg ccaagtcaac agctgtttct caggttattt caaccaaacg
    63301 catgcgtgaa aaaattgctc aaaaaccagt ttcctctgac tttagtctta aggaaacaac
    63361 cattatcaaa gaagccaaaa gtaaaactgc cctgcagttc ttggcagaaa tcaagcaaac
    63421 acgcaaggga accattaccc aaacagaaag agaactcttg caacagatgg ctggcttggg
    63481 cttgctggac gaagtcatca atatcattct tttattgacc tttaataagg tcgattcggc
    63541 aaatatcaat gagaaatatg ccatgaaggt agccaatgac tatgcctatc aaaagattca
    63601 ttcggcagaa aaggcagtct tgcgcatccg tgagcgagga cagaaagcaa aaacacaaaa
    63661 acagaatcag actgccccag taaaaaccaa tgttcctaaa tggagtaatc ctgaatataa
    63721 gaatgaaacc agcgaggaaa ctcgtctgga actagaacgt aagaagcaag aactattagc
    63781 tcgattagaa aaaggaggag attagatgga aagtgtcgga gacgtactca aacgtcaacc
    63841 cagccgtttt tattatcaag atttggtcca gaaaatcatg aaggaccctg atgttgcggc
    63901 ttttatccag caagaatcct tgactccaga ggaattaaat cgcagtatct ccaagtttaa
    63961 tcagtacatc accgagcgtg acaagtttct ccgtggggat acggattata ttgccaaagg
    64021 ctacaagccg attttggtta agaatcatgg ctatgcagat gtttcatatg aagaaactcc
    64081 tgagctaatc gcggctgaaa aagaagcggc tattaagaac cgtctcaagt taatcaatct
    64141 accagccagt ctcaagaaag ctagtttggc tcaagttgac ttggatgatt tggggcgctt
    64201 accagttttt gaaaagctac tagccttcgt ggagcaatat ccagctattc gaaaaggtct
    64261 ttacttatat ggagactttg gtgtgggtaa aagtttcatg gtggcggcct tagctcatga
    64321 tttatcagaa aaacgtggtg tttcatcaac tctcctccac tatcctagct ttgtcattga
    64381 tgtcaaaaat gctatcggtg atggcaatgt taagacctta gtggatgaga ttaagctttc
    64441 tgaagtcctg attttagatg atattggtgc cgagcaatcc accgcttggg tgcgtgacga
    64501 aatcctgcag gtcattctcc aatatcggat gcaggaaaat ttaccgacct ttttcacatc
    64561 caacttcaac tttgaagatt tggagaagca ttttgcgaaa gtgaaacatg gaaatgacga
    64621 aacctgggaa gccagacggg tcatggaacg catccgttat ttggctgagg agactcgttt
    64681 agaaggagta aaccgtcgat gacagaaacc attaaattga tgaaggctca tacttcagtg
    64741 cgcaggttta aagagcaaga aattccccaa gtagacttaa atgagatttt gacagcagcc
    64801 cagatggcat catcttggaa gaatttccaa tcctactctg tgattgtggt acgaagtcaa
    64861 gagaagaaag atgccttgta tgaattggta cctcaagaag ccattcgcca gtctgctgtt
    64921 ttccttctct ttgtcggaga tttgaaccga gcagaaaagg gagcccgact tcataccgac
    64981 accttccaac cccaaggtgt ggaaggtctc ttgattagtt cggtcgatgc agctcttgct
    65041 ggacaaaacg ccttgttggc agctgaaagc ttgggctatg gtggtgtgat tatcggtttg
    65101 gttcgataca agtctgaaga agtggcagag ctctttaacc tacctgacta cacctattct
    65161 gtctttggga tggcactggg tgtgccaaat cagcatcatg atatgaaacc gagactgcca
    65221 ctagagaatg ttgtctttga ggaagaatac caagaacagt caactgaggc aatccaagct
    65281 tatgaccgtg ttcaggctga ctatgctggg gcgcgtgcga ccacaagctg gagtcagcgc
    65341 ctagcagaac agtttggtca agctgaacca agctcaacta gaaaaaatct tgaacagaag
    65401 aaattattgt agaaagtgag aaattatggc cctaccaact attgccattg taggacgtcc
    65461 caatgttggg aaatcaaccc tatttaatcg gatcgctggt gagcgaatct ccattgtaga
    65521 agatgtcgaa ggagtgacac gtgaccgtat ttatgcaacg ggtgagtggc tcaatcgttc
    65581 ttttagcatg attgatacag gaggaattga tgatgtcgat gctcctttca tggaacaaat
    65641 caagcaccag gcagaaattg ccatggaaga agcagatgtt atcgtctttg tcgtgtccgg
    65701 taaggaagga attaccgatg cagacgaata cgtagcccgt aagctttata agacccacaa
    65761 accagttatc ctcgcagtta acaaggtgga caaccctgag atgcgaaatg atatctatga
    65821 tttctatgcc ctcggtttgg gtgaaccact gcctatctca tctgtccatg gtatcggtac
    65881 aggggatgta ctagatgcga ttgtggaaaa ccttccaaat gaatatgaag aagaaaatcc
    65941 agatgtcatt aagtttagcc tgattggtcg tccaaacgtt ggaaaatcaa gcttgatcaa
    66001 tgctatcttg ggcgaagacc gtgttattgc tagtcctgtt gctggaacaa ctcgtgatgc
    66061 cattgatacc cactttacag atacagatgg tcaagagttt accatgattg atacggctgg
    66121 tatgcgtaag tctggtaagg tttatgaaaa tactgagaaa tactctgtta tgcgtgccat
    66181 gcgtgctatt gaccgttcag atgtggtctt gatggtcatc aatgcggaag aaggcattcg
    66241 tgagtacgac aagcgtatcg caggatttgc ccatgaagct ggtaaaggga tgattatcgt
    66301 ggtcaacaag tgggatacgc ttgaaaaaga taaccacact atgaaaaact gggaagaaga
    66361 tatccgtgag cagttccaat acctgcctta cgcaccgatt atctttgtat cagctttaac
    66421 caagcaacgt ctccacaaac ttcctgagat gattaagcaa atcagcgaaa gtcaaaatac
    66481 acgtattcca tcagctgtct tgaacgatgt catcatggat gccattgcca tcaacccaac
    66541 accgacagac aaaggaaaac gtctcaagat tttctatgcg acccaagtgg caaccaaacc
    66601 accaaccttt gtcatctttg tcaatgaaga agaactcatg cacttttctt acctgcgttt
    66661 cttggaaaat caaatccgaa aggcctttgt ttttgaggga acaccgattc atctcatcgc
    66721 aagaaaacgc aaataaaaaa gtagaatctg gaatgacagt tccggatttt tttgatataa
    66781 taaaataata gaaaacgcta tcaaaagaag gggggatgtc ggtgatggaa catttgttta
    66841 aattcttact tttagcaccg tacttttatt ttgataactg gattgaaaag gccaacagaa
    66901 atagtaagtt ttttccaatt ttttattatt tttactggtt ttacatcccc ttctattctc
    66961 tttttagcct tgcttggaca gttgtttcag ttctgttttt caataccgtc ttgagaaatg
    67021 tgacagatat caagttatgg ggcatttggt ttctttttat tctgctagct attggtatga
    67081 attggttaac ttattcctgt ttcaaagaaa tgtttcgctt gagacaggaa ctagggaagt
    67141 ctaagggtgg aaggcattga tttatatcgg tttctatttg taggaggtgg cttatggtac
    67201 ctctaaaatc atttattaca cgctattcca aggtttatat tggtaataac atttaataga
    67261 acgaaactaa agaaaacaat ttaaaagagg aggtttgtga tggaacactt gtttaaaatg
    67321 ataatcttat taccctgttt ttactttttc agctggattg aaagggcaaa cagagatagt
    67381 aagattttct caatttttta ctatttttac tggatttaca tcaccctcta tgctcttttt
    67441 agtctggctt ggacagtttt ttcggtcctg ttgttcaata tcgtcttgag aaatgtggca
    67501 gacatcaagt cttggggtgt ttggctatta ttactactta tcgcttttgc tagtgattgg
    67561 ttagcctatg tctttttcaa aaaaatgatt cgcttgaggc gggaactagg gaagtctaaa
    67621 ggcggaaggc attgatttat actcttcgaa aatctcttca aaccacgtca acgtcgcctt
    67681 ggattatata tgt
//
LOCUS       DAVDFK010000008        66784 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.08, whole genome shotgun sequence.
ACCESSION   DAVDFK010000008 DAVDFK010000000
VERSION     DAVDFK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.08"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(68..1099)
                     /locus_tag="VUR04_000612"
     CDS             complement(68..1099)
                     /locus_tag="VUR04_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET5340553.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(1355..2038)
                     /locus_tag="VUR04_000613"
     CDS             complement(1355..2038)
                     /locus_tag="VUR04_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET5340554.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIHQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(2050..2994)
                     /locus_tag="VUR04_000614"
     CDS             complement(2050..2994)
                     /locus_tag="VUR04_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET5340555.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            3126..5957
                     /gene="uvrA"
                     /locus_tag="VUR04_000615"
     CDS             3126..5957
                     /gene="uvrA"
                     /locus_tag="VUR04_000615"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET5340556.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKIQKDGYVRVRVDGEVYDVTEVLELSKSRQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            5950..7011
                     /locus_tag="VUR04_000616"
     CDS             5950..7011
                     /locus_tag="VUR04_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET5340557.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            7144..7542
                     /gene="spx"
                     /locus_tag="VUR04_000617"
     CDS             7144..7542
                     /gene="spx"
                     /locus_tag="VUR04_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET5340558.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            7608..8177
                     /locus_tag="VUR04_000618"
     CDS             7608..8177
                     /locus_tag="VUR04_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5340559.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQLALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGFENLLKNEPSKYISDRLANGATEQ"
     gene            8264..8530
                     /locus_tag="VUR04_000619"
     CDS             8264..8530
                     /locus_tag="VUR04_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET5340560.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            8534..8953
                     /gene="ruvX"
                     /locus_tag="VUR04_000620"
     CDS             8534..8953
                     /gene="ruvX"
                     /locus_tag="VUR04_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET5340561.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            8969..9274
                     /locus_tag="VUR04_000621"
     CDS             8969..9274
                     /locus_tag="VUR04_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET5340562.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            9431..10681
                     /locus_tag="VUR04_000622"
     CDS             9431..10681
                     /locus_tag="VUR04_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET5340563.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            10678..11220
                     /locus_tag="VUR04_000623"
     CDS             10678..11220
                     /locus_tag="VUR04_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET5340564.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            11366..12898
                     /gene="cls"
                     /locus_tag="VUR04_000624"
     CDS             11366..12898
                     /gene="cls"
                     /locus_tag="VUR04_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET5340565.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            12976..13119
                     /locus_tag="VUR04_000625"
     CDS             12976..13119
                     /locus_tag="VUR04_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340566.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            13156..14694
                     /locus_tag="VUR04_000626"
     CDS             13156..14694
                     /locus_tag="VUR04_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET5340567.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            14814..17021
                     /gene="nrdD"
                     /locus_tag="VUR04_000627"
     CDS             14814..17021
                     /gene="nrdD"
                     /locus_tag="VUR04_000627"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET5340568.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            17033..17173
                     /locus_tag="VUR04_000628"
     CDS             17033..17173
                     /locus_tag="VUR04_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340569.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            17217..17723
                     /locus_tag="VUR04_000629"
     CDS             17217..17723
                     /locus_tag="VUR04_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340570.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFFNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            17716..18306
                     /gene="nrdG"
                     /locus_tag="VUR04_000630"
     CDS             17716..18306
                     /gene="nrdG"
                     /locus_tag="VUR04_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET5340571.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            18303..18920
                     /locus_tag="VUR04_000631"
     CDS             18303..18920
                     /locus_tag="VUR04_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET5340572.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKAGEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            19186..19494
                     /gene="rpsJ"
                     /locus_tag="VUR04_000632"
     CDS             19186..19494
                     /gene="rpsJ"
                     /locus_tag="VUR04_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET5340573.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            19711..20337
                     /gene="rplC"
                     /locus_tag="VUR04_000633"
     CDS             19711..20337
                     /gene="rplC"
                     /locus_tag="VUR04_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET5340574.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            20362..20985
                     /gene="rplD"
                     /locus_tag="VUR04_000634"
     CDS             20362..20985
                     /gene="rplD"
                     /locus_tag="VUR04_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET5340575.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            20985..21281
                     /locus_tag="VUR04_000635"
     CDS             20985..21281
                     /locus_tag="VUR04_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET5340576.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            21299..22132
                     /gene="rplB"
                     /locus_tag="VUR04_000636"
     CDS             21299..22132
                     /gene="rplB"
                     /locus_tag="VUR04_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET5340577.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            22236..22517
                     /gene="rpsS"
                     /locus_tag="VUR04_000637"
     CDS             22236..22517
                     /gene="rpsS"
                     /locus_tag="VUR04_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET5340578.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            22529..22873
                     /gene="rplV"
                     /locus_tag="VUR04_000638"
     CDS             22529..22873
                     /gene="rplV"
                     /locus_tag="VUR04_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET5340579.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            22886..23539
                     /gene="rpsC"
                     /locus_tag="VUR04_000639"
     CDS             22886..23539
                     /gene="rpsC"
                     /locus_tag="VUR04_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET5340580.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            23543..23956
                     /gene="rplP"
                     /locus_tag="VUR04_000640"
     CDS             23543..23956
                     /gene="rplP"
                     /locus_tag="VUR04_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET5340581.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            23966..24172
                     /locus_tag="VUR04_000641"
     CDS             23966..24172
                     /locus_tag="VUR04_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET5340582.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            24197..24457
                     /gene="rpsQ"
                     /locus_tag="VUR04_000642"
     CDS             24197..24457
                     /gene="rpsQ"
                     /locus_tag="VUR04_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET5340583.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            24483..24851
                     /gene="rplN"
                     /locus_tag="VUR04_000643"
     CDS             24483..24851
                     /gene="rplN"
                     /locus_tag="VUR04_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET5340584.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            24929..25234
                     /gene="rplX"
                     /locus_tag="VUR04_000644"
     CDS             24929..25234
                     /gene="rplX"
                     /locus_tag="VUR04_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET5340585.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            25258..25800
                     /gene="rplE"
                     /locus_tag="VUR04_000645"
     CDS             25258..25800
                     /gene="rplE"
                     /locus_tag="VUR04_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET5340586.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            25818..26087
                     /gene="rpsN"
                     /locus_tag="VUR04_000646"
     CDS             25818..26087
                     /gene="rpsN"
                     /locus_tag="VUR04_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET5340587.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            26372..26770
                     /gene="rpsH"
                     /locus_tag="VUR04_000647"
     CDS             26372..26770
                     /gene="rpsH"
                     /locus_tag="VUR04_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET5340588.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            26962..27498
                     /gene="rplF"
                     /locus_tag="VUR04_000648"
     CDS             26962..27498
                     /gene="rplF"
                     /locus_tag="VUR04_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET5340589.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            27582..27938
                     /gene="rplR"
                     /locus_tag="VUR04_000649"
     CDS             27582..27938
                     /gene="rplR"
                     /locus_tag="VUR04_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET5340590.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            27956..28450
                     /gene="rpsE"
                     /locus_tag="VUR04_000650"
     CDS             27956..28450
                     /gene="rpsE"
                     /locus_tag="VUR04_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET5340591.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            28422..28646
                     /gene="rpmD"
                     /locus_tag="VUR04_000651"
     CDS             28422..28646
                     /gene="rpmD"
                     /locus_tag="VUR04_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET5340592.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            28791..29231
                     /gene="rplO"
                     /locus_tag="VUR04_000652"
     CDS             28791..29231
                     /gene="rplO"
                     /locus_tag="VUR04_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET5340593.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            29244..30554
                     /gene="secY"
                     /locus_tag="VUR04_000653"
     CDS             29244..30554
                     /gene="secY"
                     /locus_tag="VUR04_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET5340594.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            30705..31343
                     /locus_tag="VUR04_000654"
     CDS             30705..31343
                     /locus_tag="VUR04_000654"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET5340595.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLT
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            31460..31678
                     /gene="infA"
                     /locus_tag="VUR04_000655"
     CDS             31460..31678
                     /gene="infA"
                     /locus_tag="VUR04_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET5340596.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            31703..31819
                     /gene="rpmJ"
                     /locus_tag="VUR04_000656"
     CDS             31703..31819
                     /gene="rpmJ"
                     /locus_tag="VUR04_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET5340597.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            31837..32202
                     /gene="rpsM"
                     /locus_tag="VUR04_000657"
     CDS             31837..32202
                     /gene="rpsM"
                     /locus_tag="VUR04_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET5340598.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            32220..32603
                     /gene="rpsK"
                     /locus_tag="VUR04_000658"
     CDS             32220..32603
                     /gene="rpsK"
                     /locus_tag="VUR04_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET5340599.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            32646..33581
                     /locus_tag="VUR04_000659"
     CDS             32646..33581
                     /locus_tag="VUR04_000659"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET5340600.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            33593..33979
                     /gene="rplQ"
                     /locus_tag="VUR04_000660"
     CDS             33593..33979
                     /gene="rplQ"
                     /locus_tag="VUR04_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET5340601.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            34244..34510
                     /locus_tag="VUR04_000661"
     CDS             34244..34510
                     /locus_tag="VUR04_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET5340602.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            34520..35857
                     /locus_tag="VUR04_000662"
     CDS             34520..35857
                     /locus_tag="VUR04_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET5340603.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            36101..36793
                     /locus_tag="VUR04_000663"
     CDS             36101..36793
                     /locus_tag="VUR04_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5340604.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTIIEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(36896..38541)
                     /locus_tag="VUR04_000664"
                     /pseudo
     CDS             complement(36896..38541)
                     /locus_tag="VUR04_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(38531..39622)
                     /locus_tag="VUR04_000665"
                     /pseudo
     CDS             complement(38531..39622)
                     /locus_tag="VUR04_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(39635..40756)
                     /locus_tag="VUR04_000666"
                     /pseudo
     CDS             complement(39635..40756)
                     /locus_tag="VUR04_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(40974..41171)
                     /locus_tag="VUR04_000667"
     CDS             complement(40974..41171)
                     /locus_tag="VUR04_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5340605.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(41246..42022)
                     /locus_tag="VUR04_000668"
     CDS             complement(41246..42022)
                     /locus_tag="VUR04_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET5340606.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            42144..42890
                     /locus_tag="VUR04_000669"
     CDS             42144..42890
                     /locus_tag="VUR04_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5340607.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            42903..43883
                     /locus_tag="VUR04_000670"
     CDS             42903..43883
                     /locus_tag="VUR04_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET5340608.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            44078..44398
                     /locus_tag="VUR04_000671"
     CDS             44078..44398
                     /locus_tag="VUR04_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5340609.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            44444..44752
                     /locus_tag="VUR04_000672"
     CDS             44444..44752
                     /locus_tag="VUR04_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5340610.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVETEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            44769..46067
                     /locus_tag="VUR04_000673"
     CDS             44769..46067
                     /locus_tag="VUR04_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5340611.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSMTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFVAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            46218..48656
                     /locus_tag="VUR04_000674"
     CDS             46218..48656
                     /locus_tag="VUR04_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET5340612.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            48675..49343
                     /locus_tag="VUR04_000675"
     CDS             48675..49343
                     /locus_tag="VUR04_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET5340613.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            49361..50449
                     /locus_tag="VUR04_000676"
     CDS             49361..50449
                     /locus_tag="VUR04_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET5340614.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            50904..53405
                     /locus_tag="VUR04_000677"
     CDS             50904..53405
                     /locus_tag="VUR04_000677"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET5340615.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTS
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSPEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLSIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            53705..53941
                     /locus_tag="VUR04_000678"
     CDS             53705..53941
                     /locus_tag="VUR04_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET5340616.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELTSIDLLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMEELVSLL"
     gene            54041..54503
                     /locus_tag="VUR04_000679"
                     /pseudo
     CDS             54041..54503
                     /locus_tag="VUR04_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398415.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            54515..54901
                     /locus_tag="VUR04_000680"
     CDS             54515..54901
                     /locus_tag="VUR04_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340617.1"
                     /translation="MITIRKQEIVKFEDVLHLYQAVGWTNYTNQPQMLEQALYHSLVI
                     YLALDGDAVVGLIRLAGDGFSSVFVQDLIVLSSYQRQGIGSSLMKQALGNFKEAYQVQ
                     LATEQTEKTWDLIVLWALKSYPPIIG"
     gene            55670..56641
                     /gene="ruvB"
                     /locus_tag="VUR04_000681"
     CDS             55670..56641
                     /gene="ruvB"
                     /locus_tag="VUR04_000681"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET5340618.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            56622..57194
                     /locus_tag="VUR04_000682"
     CDS             56622..57194
                     /locus_tag="VUR04_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET5340619.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESALELFTPYGLEDILNFQVRPTPHFL
                     ENQERMALYKTRLSKKNWQEKWKNLIFKNT"
     gene            57425..58183
                     /locus_tag="VUR04_000683"
     CDS             57425..58183
                     /locus_tag="VUR04_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET5340620.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVRIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            58192..58995
                     /locus_tag="VUR04_000684"
     CDS             58192..58995
                     /locus_tag="VUR04_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET5340621.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVGSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            59017..60276
                     /gene="rseP"
                     /locus_tag="VUR04_000685"
     CDS             59017..60276
                     /gene="rseP"
                     /locus_tag="VUR04_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET5340622.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADNGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTATDSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            60289..62142
                     /locus_tag="VUR04_000686"
     CDS             60289..62142
                     /locus_tag="VUR04_000686"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET5340623.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLTPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            62241..63620
                     /gene="bglA"
                     /locus_tag="VUR04_000687"
     CDS             62241..63620
                     /gene="bglA"
                     /locus_tag="VUR04_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET5340624.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            63812..65620
                     /gene="glmS"
                     /locus_tag="VUR04_000688"
     CDS             63812..65620
                     /gene="glmS"
                     /locus_tag="VUR04_000688"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET5340625.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGTDNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            65739..>66784
                     /locus_tag="VUR04_000689"
     CDS             65739..>66784
                     /locus_tag="VUR04_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET5340626.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
BASE COUNT        20367 a        12033 c        14873 g        19511 t
ORIGIN      
        1 tgctgtaata tgtgatgaaa atgccagtaa tgataccgag aaaaaagctg agaaactttt
       61 cccagcttta tttgttatag tcaaagcgaa tgacttgttc ctgtgcatct acatgagcat
      121 ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc gacattcaga ttatagacaa
      181 tcgggatatt gctgtcaatg atatctaata gtgcctcttt atagtcgtca tggaaagttt
      241 catccatagg ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtatccttta
      301 aagttagcaa catctttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca
      361 agaggatttt cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagct
      421 ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac
      481 cgaggatttt cccctcgaac tgggcacttc cttgcaacaa gtcaaaacct gtatttgtat
      541 gactgacacg aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa
      601 cgtcactagg gcggatttct gaaattcttc ccgtcttaat caattcttta aagtagtgaa
      661 ggctataggc tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat
      721 aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc
      781 caagaaaaat tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta
      841 gcaagcgata ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag
      901 aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc
      961 cttttaacga atgggacaaa aagatgggat tgagtcccag atccttgaga cgttggatac
     1021 ccaagtccac ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa
     1081 taccaatagt agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca
     1141 aaatataaga gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc
     1201 tcttcaaacc acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc
     1261 tagcttccta gtttgctctt tgattttcat tgagtataac tcaaaaaaag taagtgaaaa
     1321 agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg
     1381 cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg
     1441 ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc
     1501 ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact agtacagatt
     1561 tccagaaagg tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt
     1621 agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc
     1681 catagccgaa agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga
     1741 ggctagtgat gaaaagagct gagtccataa tcatcagttt tggatcatca ttttcttttg
     1801 gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc
     1861 cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg tgaatgactt
     1921 cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag
     1981 caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag
     2041 gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc
     2101 aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg ggatttcatt
     2161 atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt
     2221 cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt
     2281 ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt
     2341 ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt
     2401 tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac
     2461 gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag
     2521 ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc
     2581 tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg
     2641 caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat
     2701 ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct
     2761 ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg
     2821 agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt
     2881 ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc
     2941 aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct
     3001 tatcctttct catttttcag attttttcac actgtactat tatactacaa aatcggcctt
     3061 ttgggtaata gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa
     3121 caaagatgca agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg
     3181 atgtggagat tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt
     3241 ccagtctggc ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt
     3301 ccgcctacgc tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg
     3361 gtctcagccc agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg
     3421 tgggaacaac gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc
     3481 cttactgtat caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata
     3541 aggttttgga gttacctgaa cgccagcgcc tgcagatttt ggcccctgtc atccgtaaga
     3601 aaaaaggaca gcataagagc gttatcgaga agattcagaa agatgggtat gttcgtgtcc
     3661 gtgtggatgg ggaagtctat gatgtgaccg aagtgctaga gttgtccaag agcagacaac
     3721 acaatattga tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct
     3781 ttgattccat tgaggctgcc cttcgtatcg cagaaggtta tgtgattatc gacaccatgg
     3841 acgactctga gttgttgttc tctgagcatt atgcctgtcc agtttgtgga tttactgtcc
     3901 cagagttaga acctcgtctc ttctctttca atgctccctt tggctcttgt agtgagtgtg
     3961 acggcttggg gattaagctg gaggtggata ctgatttggt agtgccagat gccagcaaaa
     4021 ccttacatga gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca
     4081 tgttagagca ggccatgaaa gtctttggag tggctatgga taagcctttt gaggacctgt
     4141 cagaagaaga taagaacttg attctctacg gctcagatgg taaggaattc catttccatt
     4201 atgaaaatga atttggtggt gtgcgcgata tcgacattcc gtttgaggga gttatcaata
     4261 atatcaaacg tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgtctct
     4321 acatgaatga gctgacctgc ggaacctgtc aaggctatcg tctcaatgac caggccttgt
     4381 ctgtccgtgt gggcggccag caagggccac atattggaga aatctccgac ctgtctatcg
     4441 ctgaccactt ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc
     4501 gtcccattct caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact
     4561 atctaaccct gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt
     4621 tggcaaccca gattggttcc aacctatcag gtgtcctcta tatcctagac gagccgtcaa
     4681 tcggtcttca ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact
     4741 tgggcaatac tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc
     4801 tgattgacgt tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac
     4861 ctaagcaagt ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggaaaacgtg
     4921 tcatcccagt accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag
     4981 cgcgtgagaa caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag
     5041 tgacaggtgt gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca
     5101 ttgcccagaa gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga
     5161 ttgagcatgt cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt
     5221 ctaacccagc tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa
     5281 atgaagccaa gattcgaggc tacaagaagg ggcgcttcag tttcaacgtc aagggaggtc
     5341 gctgtgaagc ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg
     5401 tttatgtggc ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc
     5461 actacaagga aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat
     5521 ttttccaaca cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag
     5581 gctatgtgac cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga
     5641 agttagctag cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgagc
     5701 cgacgacagg gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg
     5761 tagacgatgg caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag
     5821 accatatcat tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag
     5881 gaactccaga agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa
     5941 agttacatca tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta
     6001 gatggtatca tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca
     6061 aacggaacag tctttatcag ccgtgaccgt caggtcttag tgacagactc tcgctatatc
     6121 atcgcagcta agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct
     6181 gtcattgcag gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt
     6241 tcagtatctt attaccaccg tatgcaggca gcttttgcag gtttggactt gcttccacaa
     6301 actcaatttg tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc
     6361 aaggcttgtt ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga
     6421 aaaactgaaa ttgaaattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct
     6481 agcttatctt ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat
     6541 ccaatgcaca aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat
     6601 gaccactatg tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag
     6661 gcagagattt acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca
     6721 ggcttaggtt tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat
     6781 ggcgactact ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc
     6841 tactttagcc agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca
     6901 ggtatctata tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag
     6961 acaggttgtg aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc
     7021 aagaaaaaag tacgaaaatg acgaaaaaag tcaaaaaaaa attaaaaata ggtcgcaagt
     7081 cggatgtttt ttatggtata atagactaaa ctgatagtaa catgtagcga aaggggtagg
     7141 tacatgatta aaatttatac agtctcaagt tgtactagct gtaaaaaagc aaaaacctgg
     7201 ctcaatgccc accagttaag ttataaagaa caaaaccttg gtaaagaagg aattacgaga
     7261 gaagaattac tggatattct aaccaaaaca gataacggaa tagccagcat cgtttcgtct
     7321 aaaaatcgct atgccaaagc ccttggagtg gatattgaag atttgagtgt caatgaagtt
     7381 ctcaatctga ttatggaaac accgagaatt ttaaagagcc caatccttgt agatgaaaaa
     7441 cgcctgcaag ttggctacaa ggaagacgat attcgtgcct tcctaccacg ctctgtccgt
     7501 aatgtagaaa atgcagaagc acgtttacgt gcagctctat aaacatcaag gctgggagca
     7561 cttcccagtc ttattctatt ttaatttcaa aaagaaagaa gagagaaatg aaaaaaatag
     7621 ttcttgttag tctagctttc ctttttgtcc tggttggttg cggacagaaa aaagaaactg
     7681 gaacagctac aaaaacagaa aaggatacgc ttcagttggc attgccagtt attgaaaatg
     7741 ccgagaagaa tacagttgta accaagactt tggtcttgcc caagtcagat gatggtagcc
     7801 agcaaactca aaccattaca tacaaggaca agactttttt gagcttaacg attcaacaaa
     7861 aacgtccagt ttctgatgag ttgaagactt atatcgacca acatggagtg gaagaaactc
     7921 aaaaagctct tcttgaagcg gaggagaagg ataagtctat cattgaagct cgtaaattgg
     7981 caggtttcaa acttgaaaca aaactattga gcgcaacgga acttcaaaca acgactagtt
     8041 ttgattttca agttctggat gtcaagaagg cttcccagtt ggaacatctg aagaatattg
     8101 gttttgaaaa tcttttgaaa aatgaaccaa gcaaatatat ttcagataga ttggcaaatg
     8161 gcgcgacaga acaatagaaa atccaaataa atagactgcc tgaattgtag aaggtaagga
     8221 attatgctat aatggtacta ttctaaggaa agagggtgtt agaatgggat ttactgaaga
     8281 aacagtacgt tttaaattgg acgattccaa taaaaaagaa attagcgaaa ctttgacaga
     8341 tgtttatgct tcgttgaacg ataagggtta caacccaatt aaccaaatcg taggttacgt
     8401 attgagtgga gaccctgcct acgttcctcg ttataataat gcacgaaatc aaatccgtaa
     8461 gtatgagcgt gatgaaatcg ttgaggaatt ggttcgttac tacctcaaag gacaaggagt
     8521 cgatctataa cctatgagaa ttatgggatt ggacgtcggt tcaaaaacgg taggggtggc
     8581 gattagcgat ccgcttggtt ttacagctca agggcttgaa atcatccaga taaatgaaga
     8641 acaaggccaa tttggttttg accgcgttaa ggaattggtt gatacttaca aggtggaacg
     8701 atttgtagtg ggcttgccta aaaacatgaa caatacaagt ggaccgcgcg tggaagctag
     8761 tcaagcatac ggagcaaagc tagaagagtt ttttggttta ccagtagact atcaggatga
     8821 acgcttgaca acagtggctg ctgagcgcat gttgattgaa caagcagata tcagtcgcaa
     8881 taagcgcaag aaagtcattg ataagttagc agctcagctg attttacaaa attatttaga
     8941 tagaaaattt taatataaag gagaggctat gtcacacgat cataaccacg accacgaaga
     9001 acgtgaacta atcacactag tagatgagca aggaaatgaa accttgtttg aaatcctttt
     9061 gacaattgat ggaaaagaag aatttggtaa aaactatgtt cttctagtac cagttaacgc
     9121 agaagaagac gaagacggac aagttgaaat ccaagcttac tcattcatcg aaaacgaaga
     9181 tggaacagaa ggcgaattgc aaccaatccc agaagactca gaagacgaat ggaacatgat
     9241 tgaagaagtc ttcaacagct ttatggagga gtaaaaacgt ccggggggcg tttttagccc
     9301 acgttcacat tcatagtagc tagttattag ctaaccaggt aagaggtcgg gacgaaaatc
     9361 ctggccttgt ttttattagt aactatactt taatgcgata attgattgga cttttgtcaa
     9421 ggagatgtgt atgtttgaag tagaagaatg gcttcatagt cggattggtt tgaattttcg
     9481 atcaggtttg ggccgaatac agcaagcggt ggatttgtta ggaaatcctg agcagtctta
     9541 ccctattatc cacgtaacag ggactaatgg gaaaggatct accattgctt ttatgaggga
     9601 attatttatg gggcatggca aaaaagttgc gacctttacc tcccctcata tcgtatccat
     9661 caatgaccga atttgcatta atgggcaacc tatagcagac gcagacttta tccgtttggc
     9721 tgatcaggta aaggagatgg agaaaacact tctgcaaact cctgaccagt tgtccttttt
     9781 tgaattgctg accttggttg cttttcttta ttttagggag caggaggtgg atttggtttt
     9841 attagaagtg ggaattggtg gcttacttga cacgaccaat gtggtaactg gagagcttgc
     9901 tgtcatcacc tccattgggc ttgaccatca agaaaccttg ggtgatagtc tagaagcaat
     9961 tgcagagcag aaagctggta ttttcaaggc tggtaaaaag gcagtgattg cgaaattgcc
    10021 tccagaagct agacttgtct gtcagaaaaa agccgaatct ttagctgttg acctttatca
    10081 ggcaggtcaa gatttttcag tgctgaatgg tgatttttca agctctttac taaatctttc
    10141 acagctgaac ataggcttag aaggagccta tcagcaggag aatgcggcct tggcgttgca
    10201 aacttttctt ctttttatgg gagaaagaaa ggaagctatt gatgaacagg ctgtaagaaa
    10261 ggccttggaa cagacccatt gggctggtcg cttggagcgt attcgcccac agatttactt
    10321 ggatggtgct cataacctcc ctgccttgac tcgcttggtt gagtttatca aagaaaaaga
    10381 gcaggaaggc tatcgacctc aaatcctctt tggatccttg aaacgtaagg attatcaagg
    10441 gatgttgggt tatctgactg aaaatttacc tcaagtggaa ctcaaaatga ccggctttga
    10501 ctatcaaggg tctttggacg agacagatgt aacaggttac catgtaattc cctcttaccg
    10561 agaatttatc agcagtttcg aagaaagggc agacgctcaa gacttgctgt tcgttacagg
    10621 gtctctctat tttatctcag aagtacgggg ctacctgctg gaccgtgagc agataaattg
    10681 accccctttt ttgaacttgt tatactaggg gaattgctgg ttagagaaaa tttctctaaa
    10741 ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat tcacactttc tcttgcttct
    10801 ctagcaagtt ttagtctctt agtagcttgt tcacaaagag ctcaacaggt tcaacagcct
    10861 gttgctcagc aggtccaaca gcctgctcaa cagaatacca atactgcaaa tgcaggaggt
    10921 aaccaaaatc aagcggctcc agtacaaaac caacctgttg ctcaaccgac cgatattgat
    10981 gggacttata ctggtcagga tgacggagac cgtatcactt tagtggtaac tggaacgact
    11041 ggtacatgga ctgagctcga atctgacggg gatcagaaag tcaaacaggt tacatttgat
    11101 tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa tttacactgt aaacggtaat
    11161 caaatcgtcg tagatgatat ggatagagac ccatcggacc aaatcgtttt aactaaataa
    11221 gactatgcaa gtagaaaggg ctggattttt cagccttttt acttttacct agaaaataat
    11281 cataaatact tgccttctac cgaatacctg cgttatacta gtatcaatta cttgttttta
    11341 gcattcaaac tatcaaggag gggatatgaa atataggaaa tttcaattat tgatgtccaa
    11401 gtatggcttt agtctttcga ttatgctact tgaactttgt cttgtttttg gtctctttct
    11461 ttatttagga cgcatggctc ccattttatg gattactgtc ctcattctac tgagtatcat
    11521 cacaatcatt tcgatagtca accgtaatac gactcctgag aataaggtaa cctggttgtt
    11581 agtagccttt gtgccagtat ttggtccctt gctctatctg atgtttggtg aaaggcgatt
    11641 gtccaaaaaa gaaatcaaac aactgaagaa gctaggctct atgcatttcc aagaagcaaa
    11701 tagccagcta ctaaaagaga aattaaaaga aagtgacaag gcagcttatg gagtcatcaa
    11761 gtccttattg agtatggata ccaatgctga catctatgat caaactgcct ctacattttt
    11821 tcctaacgga gaagctatgt ggaaaaagat ggtagaagat cttaaaaagg ctgagaaatt
    11881 tattttcttg gaatattaca ttatagaaga aggtttgatg tggaatcgca tactagatat
    11941 actagagcaa aaggtagctc agggtgtaga ggttaagatg ctctatgatg atatcggctg
    12001 tatggctact ttaacaggag attatgcaca tcgacttcgt cagctgggca tcgaggccca
    12061 taaattcaat aaagttattc ctcgtttgac agtggcttat aataacagag atcatagaaa
    12121 aatattgatt gttgatggtc agatagccta tactggtggg gtcaatctgg cagatgagta
    12181 cattaaccac gtcgagagat ttggttattg gaaggatagt ggaattcgct tagacggact
    12241 agcagtaaaa gctctgacac gcttattttt gaccacttgg tacattaatc gaggagaaat
    12301 tagtgatttt gatcaatatc atttagaaaa tcattctatc ccgagtgacg gtttaaccat
    12361 tccatacgga agtggaccca agccaatttt tcgagcgcag gtagggaaaa aagtttatca
    12421 gagtttaatc aatcaagcaa cagaatcggt ctatattacg acaccttatt tgattataga
    12481 ttatgattta acagagacaa tcaaaaatgc agctatgaga ggggtcgatg ttcgaattat
    12541 caccccttac ataccagata agaagttcat tcagttagtc acgagaggag cttatcccga
    12601 ccttctttct gctggtgttc ggatttatga gtatagtcca ggttttattc atagtaagca
    12661 gatgttggta gacgaagatt ttgcggtggt ggggacaatc aatctcgact accggagctt
    12721 ggtacaccat tatgaaaatg cagtcttact ctataaaact ccttctataa gggaaatcgc
    12781 ccgagatttt cgaaatatat ttgcagattc tcaggaagtc tatcctcatt ctatcaaaac
    12841 gagctggtat caaaagcttg taaaagaaat cgcccagcta ttcgccccta tcttataaga
    12901 aatctagaac ttaggataca aaccagacct atttttcttg tcttttacga atagaaagaa
    12961 agaggagggg aattcatgct aactaaggaa gaagtgaatg atatgattga gttcaaacag
    13021 acacatttac accgctttcg ggaaattgaa acctttgtga aactatgcaa aaaatcactc
    13081 aaacagccat cgcaagctga caatcctagg actttttgat atactaagac agataaattg
    13141 aacgggagaa acgatatgag tgtgtatggt agagtagaag aagttcataa ggagaatcgt
    13201 gaacctctag aataccaaat cgaacaagaa tcgcatcatc gtgaatcaag tcgtcttcct
    13261 ttggtgaaaa ttttactatg gagtacgctt gtaacgggga taactctagg agtaccgcta
    13321 ttactcgact taatgagtgc acaagaagtg caggattttt atgcaggttg ggcgcttcat
    13381 cagacaggga agatttacag cgactattat ggaagtcaag gtttgcttta ttatttgctg
    13441 acttacgtga gtcagggcgg atttttcttt gccatctttg agtggttagc cttggtagca
    13501 ggaggatttt tcctttttag atcagcggac accttgacag agcaaggaga ccaagctgga
    13561 catctggtga ctatttttta catgctagtt acaggtcttg cttttggtgg aggctatgcg
    13621 actcttttag cgcttccttt cttattcgca gcctttagtt tagttgcggc ttacctaagc
    13681 aatccaagcc atgataaggg atttgtacgg attgggctag ctttggcagg cggatttttc
    13741 tttgctccct tatcatcgct cctgtttatt gctgtagtga gtttaggctt gttggtcttt
    13801 aaccttgggc atagacgctt tgcgcatggg ttttatcagt ttcttgcagt ggctttaggt
    13861 ttttcacttg tcttttatcc aactgcctac tatagtgctg caacaggaag ttttggggat
    13921 gcgattagtg gtattcgtta tcctattgac agtattcgct ttgattttac ttctaaaatt
    13981 ttagagaata tgttttttta tggcttgttg tcccttggtt tgggatttgt ggtttgtatc
    14041 tttttaggtc tctttcaatc caaacccttt aaactatacg tcatttcggt tcctgcaagt
    14101 cttgtggtaa ttttaggttt gattttactt ttcttttcac aagagcctct gcacgcttct
    14161 tatttgatgg tcgtcttccc tgttttccta cttttattgg taaccaatat taagagtcaa
    14221 cagagggggc gtagtgctag aagaagccga agagaaacgc cagttagcct atggagtcgt
    14281 ttcttcaaag gaaatctata tctgctagtt tttgggtttg tctatctttt gtctgttcct
    14341 tttttgatga agtttgtcct ttatccagta ccttatcaag aacgtaatcg tcttgctgat
    14401 ttggtaaaag aggagacaaa tacggaagat gctatctatg catgggatga tactgcgact
    14461 ctttatcgta agagtgagcg cttgtcgcca tcggcgattt tgtccccgtt gcactataca
    14521 gcaactgagg aaaatcgtaa taagttactt aatgacttga aagaaaaaca acctaaggtg
    14581 attgtggtaa atgacaaggt ggaagtctgg tctgaagtgg aaacactctt aaaagaaaat
    14641 taccaacaag taaagactga ttactcagag tttaaagtct ataaaattaa ataaccaaat
    14701 caatatcttg tgtattttta aaaattttaa gatttttaac acaagatatt gatttttctt
    14761 tttagagtgg tataatactt tttagaaaga acattttaga aaagagcatg catatgattg
    14821 cactagaaga aaaaattaca attttgccaa ctctcttcgt cgagaaacga gatgggagac
    14881 gtgttgtatt tgatgtggac aagattgaca aggctctcca caaggcagct gacaaggtta
    14941 tggatgtgac acccctggtt gaaaaacgcc tcaatgatct gactgagaga attattacag
    15001 aaattcatag tcgctttcca cagggaatta agatttacga aattcaaaat atcgtagaac
    15061 atgaactcct tgaagccaaa gaatatgcgc tggctgagga gtatattact tatcggacac
    15121 agagggattt tgagcgctca aaagcgacgg atatcaactt tagtattcat aaacttctca
    15181 acaaagacca gacagttgtc aatgaaaatg ctaataaaga cagtgatgtc tttaacactc
    15241 agcgtgattt gacagcaggg attgttggga aatcaatcgg actgcaaatg cttcctaagc
    15301 acgtagccaa tgcccaccaa aagggggata tccactatca cgatttggac tacagtccct
    15361 atacccctat gaccaactgc tgtttgattg attttaaggg tatgttggaa aatggtttta
    15421 agattggaaa tgcagaggta gagagtccca agtctatcca gactgcgaca gcacagattt
    15481 ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg ctgttcagct gaccgtatcg
    15541 atgaaatttt ggcgccttat gcagagaaga actatcaaaa acatctcaaa gatgcagaag
    15601 agtgggtatt gcctgaaaaa cgggaagatt acgcttggaa gaaaacgcaa aaggacatct
    15661 acgatgccat gcaatctctt gagtatgaaa tcaatactct cttcacttca aatggacaaa
    15721 caccttttac ttcgctaggt tttggtctgg gaaccagtcg ttttgaacga gaaattcaaa
    15781 aagctatttt aaacattcgc atcaagggtc ttggttcaga acaccgtacg gctatctttc
    15841 ctaaacttat tttcactctg aaaagaggcc ttaatttaga ggaaggaact cccaactacg
    15901 acatcaagca gttggctctt gagtgtgcaa ccaaacggat gtatccagat gttttatctt
    15961 acgataagat tgttgacttg acaggatcct tcaaggtgcc tatgggttgc cgttctttcc
    16021 tccaaggatg gaaggatgaa aatggtgtag aagtcaattc aggtcgcatg aatctgggtg
    16081 ttgtgacggt taatctgcct cgtattgctc ttgagtctga aggtgatatg aataagttct
    16141 gggaaatctt caacgagcga atgaatatcg cagaagatgc tcttgtttac cgtgtcgaac
    16201 gcactaaaga ggcgacacca gcgaatgctc ctatccttta tcagtacggt gcttttggcc
    16261 atcgtctagg taaagaagaa agtgttgacc agctctttaa gaatcgtcgt gcgaccgttt
    16321 cgctgggcta tatcggcttg tatgaagtag cgacagtttt ctttggtaac agctgggaaa
    16381 gtaatccaga tgctaaggaa ttcacgctag acatcattca cgatatgaaa cgccgtgtag
    16441 aagagtggtc agaccaatat ggctaccatt tctctatcta ctcaacacca tccgaaagtc
    16501 tgacagaccg tttctgccga ctagatatag acaagtttgg ctctattcct gatatcacag
    16561 acaaggaata ctacaccaac tctttccact acgatgttcg taaaaatcca acaccgtttg
    16621 aaaaattgga ctttgagaaa gtctatccag aagcaggtgc gtcaggtggt ttcatccatt
    16681 attgtgagta tccagtcctt cagcaaaatc caaaggcctt ggaagctgtc tgggattatg
    16741 cttatgaccg tgtaggctat ctaggcacca atactccgat tgaccgttgc tacaagtgtg
    16801 actttgaagg ggattttgaa ccaactgaga gagggtttgc ttgtccaaac tgtggcaata
    16861 gcgaccctaa aacagtagat gtggtgaagc gaacttgtgg ctacctaggt aatcctcaag
    16921 caagaccgat ggtcaacggg cgtcacaagg aaatcgctgc gcgtgtcaaa catatgaatg
    16981 gttcaacgat taaaatagct gggcatcaag taacaaatta gaaagaaatg aaatgggaaa
    17041 atatcaacta gacgataagg ggcgcgcaca agtgacccgt tatcacgaga aacactctaa
    17101 aggtggagct ggtaagaaag aacgcttgct tagcttcaga gaacaatttt taaacaagaa
    17161 caagaaaaaa taaaagtgag agccagctct cgcttttctc atagtgggag gtaaggatgg
    17221 aattacgcag accaagatta gcggataaga aagctgtttt agatatgatg acagagtttg
    17281 aaaagagcca atcagcccat gatggaggat tttgggatac agagaatttt gtgtatgaag
    17341 agtggttgga aagcaatcag gaacaggaaa tggggattaa tctgcctgaa ggatgggttc
    17401 ctgcaattca gttagtggct ttttctgaga aaggtcaagc agttggattt tttaatctcc
    17461 ggttgcgcct cagtaacttt ttactagaag aaggtgggca cattggctac tccatccgtc
    17521 catctgaaag aggcaagggt tatgcaaaag agactctccg tcagggcttg caagttgcta
    17581 aggaaaagaa catcaagaaa gctctggtga cctgtagcgt gaataatcct gctagcagag
    17641 cagtcattct agcaaatggt ggaatatttg aggatgctca caatggagtc gagcgttatt
    17701 ggatagaggt agcgaatgaa taatccaaaa ccacaagaat ggaaaagcga ggaacttagt
    17761 caaggtcgta tcattgacta caaggccttt aactttgttg atggcgaagg cgtgcgtaac
    17821 tctctctatg tatcaggctg tatgtttcac tgcgagggat gttataatgt tgcgacttgg
    17881 tcttttaatg ctggcattcc ctatacagca gaattagaag agcagatcat ggcagacctt
    17941 gcccaaccct atgttcaagg cttgactttg ctgggagggg aaccttttct caatactggc
    18001 attctcttgc ctctagttaa acgcatccga aaggaattgt cagacaagga catttggtcc
    18061 tggacgggct acacttggga agaaatgatg ttggaaactc cagataaact ggaactctta
    18121 tcattgattg acattcttgt cgatggacga tacgatcgaa ctaagagaaa tctcatgctc
    18181 cagtttcgag gttcgtccaa ccaacgaatt atcgatgtgc aaaaatcgct caaaagtggg
    18241 caagtagtga tttgggacaa gctcaatgac ggaaaagaaa gctatgaaca ggtgaagaga
    18301 gaatgaagaa aaaagactta gtagaccaac tagtctcaga gatcgagacg gggaaagtca
    18361 ggacactggg aatatacggt catggagctt caggtaaatc aacctttgca caggaattgt
    18421 accaagcttt agattctact acagtaaatt tgctagaaac agatccctat atcacctcag
    18481 gacgccatct ggtagtaccc aaggacgcgc cgaatcaaaa ggtgacagcc agtctgccag
    18541 tggcgcatga actggagagt ttgcagagag atatccttgc cttgcaggcg ggtatggatg
    18601 tcttgacaat tgaagaacct tggaaggctg gtgaggtctt gtctggagcc aaaccaattt
    18661 tgattgtcga agggatgtct gttggctttc tacccaagga actatttgaa aaaaccatct
    18721 gtttctacac ggatgaggag accgaattaa agcgacgcct tgctagagat acgactgtga
    18781 gaaatcgtga tgcatccttt atattggcta gccatcagat gagacgggag cagtatctgc
    18841 gatactataa agaaactgag tctaaggcgg atatcttagt ggatcaatca gaagataaat
    18901 ttgatgtcaa gaggacttaa cttatgtata gaagaaatat agaagaaaat ccctaatttt
    18961 agaaagaaaa agtaggaaaa cagtttcatc ccaaaaaaac gaaaaaacct aacaaatccc
    19021 ttgcaatcgc aggggatttg tgttattcta ttatggtgct gtaaattaca gccttagttt
    19081 tgatgcaaga ggttgcgaca cgctcggttg cattgccacg caacaccgtg tcggttttct
    19141 tgtggagcta gcctattatc ttaaatagac gaaaaggaga aaaagatggc aaacaaaaaa
    19201 atccgtatcc gtttgaaagc ttacgaacac cgtacgcttg acacagcggc tgcaaaaatc
    19261 gtagaatcag ctactcgtac aggtgcacaa gttgcgggtc caatcccact tccaactgaa
    19321 cgtagcctct acacaatcat tcgtgcgact cacaaataca aagactctcg cgaacaattt
    19381 gaaatgcgta cacacaaacg tttgatcgat atcgttaacc caactcaaaa aacagttgat
    19441 gccttgatga aattggatct tccaagtggt gtaaacgtag aaatcaaact ttaatctaaa
    19501 atataaaaga gcagaggctg gtgtttcaat ctaattgaac acgggctaaa ctcggtgtga
    19561 aaaagataaa cttcctagtg tctgctagac actgcgtcag tttcctattt tcaagttgag
    19621 tttgacgccc tttgtatctt agacttgagc ataaaaaacg ctcgttaaaa actttttgaa
    19681 taaaaaatat agaaaaggaa ctattttctc atgacaaaag gaatcttagg gaaaaaagtg
    19741 ggaatgactc aaatcttcac tgaagctggc gaattgatcc ctgtaacagt tattgaagca
    19801 actccaaacg ttgttcttca agttaaaact gttgaaacag acggatacaa cgctatccaa
    19861 gttggtttcg atgacaaacg cgaagtattg agcaacaaac ctgctaaagg acatgtagcg
    19921 aaagctaaca cggctcctaa gcgcttcatt cgtgaattca aaaacgttga aggcttggaa
    19981 gttggcgctg aaatcacagt tgaaacattc gcagctggag atgttgttga tgtaactggt
    20041 acttctaaag gtaaaggttt ccaaggtgtt atcaaacgcc acggacaatc acgtggacca
    20101 atggctcacg gttctcgtta ccaccgtcgt ccaggttcta tggggcctgt tgcacctaac
    20161 cgcgtattca aaggtaaaaa ccttgcagga cgtatgggtg gtgaccgcgt aacaattcaa
    20221 aatcttgaag ttgtacaagt tgttccagaa aagaacgtta tccttatcaa aggtaacgta
    20281 ccaggtgcta agaaatctct tatcactatc aaatcagcag ttaaagctgg taaataataa
    20341 agaaagggga aatcagtcac aatggcaaac gtaacattat ttgaccaaac tggtaaagaa
    20401 gctggccaag ttgttcttaa cgatgcagta tttggtatcg aaccaaatga atcagttgtg
    20461 tttgatgtaa tcatcagcca acgcgcaagc cttcgtcaag gaacacacgc tgttaaaaac
    20521 cgctctgcag tatcaggtgg tggacgcaaa ccgtggcgtc aaaaaggaac tggacgtgct
    20581 cgtcaaggtt ctatccgctc accacaatgg cgtggtggtg gtgttgtctt cggaccaact
    20641 ccacgttcat acggctacaa acttccacaa aaagttcgtc gcctagctct taaatcagtt
    20701 tactctgaaa aagttgctga aaacaaattc gtagctgtag acgctctttc atttacagct
    20761 ccaaaaactg ctgaatttgc aaaagttctt gcagcattga gcatcgattc taaagttctt
    20821 gttatccttg aagaaggaaa tgaattcgca gctctttcag ctcgtaacct tccaaacgtg
    20881 aaagttgcaa ctgctacaac tgcaagtgtt cttgacatcg caaatagcga caaacttctt
    20941 gtcacacaag cagctatctc taaaatcgag gaggttcttg cataatgaat ttgtatgatg
    21001 ttatcaaaaa acctgtcatc actgaaagct caatggctca acttgaagca gggaaatatg
    21061 tatttgaagt tgacactcgt gcacacaaac ttttgatcaa gcaagctgtt gaagctgctt
    21121 tcgaaggtgt taaagttgcc aatgttaaca caatcaacgt aaaaccaaaa gctaaacgtg
    21181 ttggacgtta cactggtttt actaacaaaa ctaaaaaagc tatcatcaca cttacagctg
    21241 attctaaagc aatcgagttg tttgctgctg aagctgaata atctaaggag gaaatatcgt
    21301 gggaattcgt gtttataaac caacaacaaa cggtcgccgt aatatgactt ctttggattt
    21361 cgctgaaatc acaacaagca ctcctgaaaa atcattgctt gttgcattga agagcaaggc
    21421 tggtcgtaac aacaacggtc gtatcacagt tcgtcaccaa ggtggtggac acaaacgttt
    21481 ctaccgtttg gttgacttca aacgtaataa agacaacgtt gaagcagttg ttaaaacaat
    21541 cgagtacgat ccaaaccgtt ctgcaaacat cgctcttgta cactacactg acggtgtgaa
    21601 agcatacatc atcgctccaa aaggtcttga agtaggtcaa cgtatcgttt caggtccaga
    21661 agcagatatc aaagtcggaa acgctcttcc acttgctaac atcccagttg gtactttgat
    21721 tcacaacatc gagttgaaac caggtcgtgg tggtgaattg gtacgtgctg ctggtgcatc
    21781 tgctcaagta ttgggttctg aaggtaaata tgttcttgtt cgtcttcaat caggtgaagt
    21841 tcgtatgatt cttggaactt gccgtgctac agttggtgtt gtcggaaacg aacaacatgg
    21901 acttgtaaac cttggtaaag caggacgtag ccgttggaaa ggtatccgcc caacagttcg
    21961 tggttctgta atgaacccta acgatcaccc acacggtggt ggtgaaggta aagcaccagt
    22021 tggtcgtaaa gcaccatcta ctccatgggg caaacctgct cttggtctta aaactcgtaa
    22081 caagaaagcg aaatctgaca aacttatcgt tcgtcgtcgc aacgagaaat aatattaaac
    22141 tagtcgctta agcaactagt aaatccgcca gctcggtagc gctccatagg agtgcaagcc
    22201 gctgtggtac aacatttaaa ggagaaaata taaaaatggg acgcagtctt aaaaaaggac
    22261 ctttcgtcga tgagcatttg atgaaaaaag ttgaagctca agctaacgac gaaaagaaaa
    22321 aagttattaa aacttggtca cgtcgatcaa cgatcttccc aagtttcatt ggttacacta
    22381 ttgcagttta tgacggacgt aaacacgtac ctgtttacat ccaagaagac atggtaggcc
    22441 acaaacttgg tgaatttgca ccaactcgta cttacaaagg tcacgctgca gacgacaaga
    22501 aaacacgtag aaaataagga gaacataaat ggcagaaatt acttcagcta aagcaatggc
    22561 tcgtacagta cgtgtttcac ctcgtaaatc acgtcttgtt cttgataaca tccgtggtaa
    22621 aagcgtagcc gatgcaatcg caatcttgac attcactcca aacaaagctg ctgaaatcat
    22681 cttgaaagtt ttgaactcag ctgtagctaa cgctgaaaac aactttggtt tggataaagc
    22741 taacttggta gtatctgaag cattcgcaaa cgaaggacca actatgaaac gtttccgtcc
    22801 acgtgcgaaa ggttcagctt caccaatcaa caaacgtaca gctcacatca ctgtagctgt
    22861 tgcagaaaaa taaggaggta aaatcgtggg tcaaaaagta catccaattg gtatgcgtgt
    22921 cggcatcatc cgtgattggg atgccaaatg gtatgctgaa aaagaatacg cggattacct
    22981 tcatgaagat cttgcaatcc gtaaattcgt tcaaaaagaa cttgctgacg cagcagtttc
    23041 aactattgaa atcgaacgcg cagtaaacaa agttaacgtt tcacttcaca ctgctaaacc
    23101 aggtatggtt atcggtaaag gtggtgctaa cgttgatgca ctccgtgcaa aacttaacaa
    23161 attgactgga aaacaagtac acatcaacat catcgaaatc aaacaacctg atttggatgc
    23221 tcaccttgta ggtgaaggaa ttgctcgtca attggagcaa cgtgttgctt tccgtcgtgc
    23281 acaaaaacaa gcaatccaac gtgcaatgcg tgctggagct aaaggaatca aaactcaagt
    23341 atcaggtcgt ttgaacggtg cagatatcgc ccgtgctgaa ggatactctg aaggaactgt
    23401 tccgcttcac acacttcgtg cagatatcga ttacgcttgg gaagaagcag atactacata
    23461 cggtaaactt ggtgttaaag tatggatcta ccgtggtgaa gttcttccag ctcgtaaaaa
    23521 cactaaagga ggtaaataac caatgttagt acctaaacgt gttaaacacc gtcgtgagtt
    23581 ccgtggaaaa atgcgcggtg aagcaaaagg tggaaaagaa gtagcattcg gtgaatacgg
    23641 tcttcaagct acaactagcc actggatcac taaccgccaa atcgaagctg ctcgtatcgc
    23701 catgactcgt tacatgaaac gtggtggtaa agtttggatt aaaatcttcc cacacaaatc
    23761 atacactgct aaagctatcg gtgtgcgtat gggatctggt aaaggggcac ctgaaggttg
    23821 ggtagcacca gttaaacgtg gtaaagtgat gttcgaaatc gctggtgtat ctgaagagat
    23881 tgcacgtgaa gcgcttcgac ttgctagcca caaattgcca gttaaatgta aattcgtaaa
    23941 acgtgaagca gaataaggag aaggcatgaa acttaatgaa gtaaaagaat ttgttaaaga
    24001 acttcgtggt ctttctcaag aagaactcgc gaagcgcgaa aacgaattga aaaaagaatt
    24061 gtttgaactt cgtttccaag ctgctactgg tcaattggaa caaacagctc gcttgaaaga
    24121 agttaaaaaa caaatcgctc gtatcaaaac agttcaatct gaagcgaaat aatagactag
    24181 ggaaggagaa atttcaatgg aacgcaataa tcgtaaagtt cttgttggac gtgttgtatc
    24241 tgacaaaatg gacaagacaa tcacagttgt agttgaaaca aaacgtaacc acccagtcta
    24301 tggtaaacgt attaactact ctaaaaaata caaagctcat gatgaaaaca atgttgccaa
    24361 agaaggcgat atcgtacgta tcatggaaac tcgcccgctt tcagctacaa aacgtttccg
    24421 tcttgtagaa gttgttgaag aagcggtcat catctaatca aacctgaaag gagaaaactg
    24481 aaatgattca aacagaaact cgtttgaaag tcgcagacaa cagcggtgct cgcgaaatct
    24541 tgactatcaa agttcttggt ggttcaggac gtaaatttgc aaacatcggt gatgttatcg
    24601 tggcatctgt aaaacaagct actcctggtg gtgcggttaa aaaaggtgac gttgttaaag
    24661 cagttatcgt tcgtactaaa tcaggtgctc gtcgtgctga tggttcatac atcaaatttg
    24721 acgaaaacgc agcagttatc atccgtgaag acaaaactcc tcgcggaaca cgtatctttg
    24781 gcccagttgc acgtgaattg cgtgaaggtg gcttcatgaa gatcgtgtca cttgctccag
    24841 aagtacttta atttttagga acaaactagt cccctagctt caagctaggg tgcccttatg
    24901 ggcgtaagaa aaatcaagga gaaacctaat gtttgtaaaa aaaggcgaca aagttcgcgt
    24961 aatcgctggt aaagataagg gaacagaagc tgttgtcctt actgcccttc caaaagtaaa
    25021 caaagttatc gttgaaggtg ttaacattgt taagaaacac caacgtccaa ctaacgagct
    25081 tcctcaaggt ggtatcatcg agaaagaagc agctatccac gtatcaaacg ttcaagtttt
    25141 ggacaaaaat ggtgtagctg gtcgtgttgg ttacaaattt gtagacggta aaaaagttcg
    25201 ctacaacaaa aaatcaggcg aagtgcttga ttaatcacga aggaaaggag aagtataatg
    25261 gcaaatcgtt taaaagaaaa atatcttaat gaagtagttc ctgctttgac agaacaattc
    25321 aactactcat cagtgatggc tgtgcctaaa gtagataaga ttgttttgaa catgggtgtt
    25381 ggtgaagctg tatcaaacgc taaaagcctt gaaaaagctg ctgaagaatt ggcacttatc
    25441 tcaggtcaaa aaccacttat cactaaagct aaaaaatcaa tcgccggctt ccgtcttcgt
    25501 gaaggtgttg cgatcggtgc aaaagttacc cttcgtggtg aacgtatgta cgaattcttg
    25561 gataaattgg tatcagtttc acttccacgt gtacgtgact ttcacggtgt tccaacaaaa
    25621 tcatttgatg gacgtgggaa ctacacactt ggtgtgaaag aacaattaat cttcccagaa
    25681 atcaacttcg atgacgttga caaaactcgt ggtcttgaca tcgttatcgt aacaactgct
    25741 aacactgacg aagagtcacg tgcattgctt acaggccttg gaatgccttt tgcaaaataa
    25801 tataggaggt aaatctaatg gctaaaaaat caatggtagc tagagaggct aaacgccaaa
    25861 aaattgttga ccgttatgct gaaaaacgtg ctgcattaaa ggcggcaggg gactacgaag
    25921 gtttatctaa attacctcgc aacgcctcac cgactcgttt acataatcgt tgtagagtta
    25981 cggggcgccc acattcagtt taccgcaaat ttggtctgag tcgtatcgct tttcgcgaac
    26041 ttgcgcataa aggtcaaatt cctggtgtaa caaaagcatc ttggtaattt aagatatcaa
    26101 gagcgtcaaa actccaagta aaaataggaa acttgatgaa gaaactaaag tttctaggaa
    26161 agtttatctt tttcacacag agtttagcct gggttcaatt gggcttgcca atttgaacac
    26221 gagctacagc tttggcaaaa aagaccaatt tgctttggag cattgcttct gcattaaatt
    26281 gtctattttt gctcgtgctg ttacgctctt tgtatcacgt attaactagc aagtgcaact
    26341 tgcaaactac tagtaagagg agaaaaacaa aatggttatg actgacccaa tcgcagactt
    26401 cctaactcgt attcgtaatg ctaaccaagc taaacacgaa gtacttgaag tacctgcatc
    26461 aaacatcaaa aaagggattg ctgaaatcct taaacgcgaa ggttttgtaa aaaacgttga
    26521 aatcattgaa gatgacaaac aaggcgtcat ccgtgtattt cttaaatacg gaccaaatgg
    26581 tgagaaagtt atcactaact tgaaacgtgt ttctaaacca ggacttcgtg tctacaaaaa
    26641 acgtgaagac cttccaaaag ttcttaacgg acttggaatt gccatccttt caacttctga
    26701 aggtttgctt actgataaag aagcacgcca aaagaatgtt ggtggtgagg ttatcgctta
    26761 cgtttggtaa aatcaagata caaagctcgt aaagaacaaa gcaaaattag gaagttggag
    26821 aagtttgttt acaaacaagc caacttatct attttgcaca gttcttagag cgtgttcagt
    26881 tcagctcttg aactaaataa gtatctgaac cccgtgaaaa ctggccgttt tggcctgaca
    26941 atttaacagg agaaaataaa catgtcacgt attggtaata aagttatcgt gttgcctgct
    27001 ggtgttgaac tcgctaacaa tgacaacgtt gtaactgtaa aaggacctaa aggagaactt
    27061 actcgtgagt tctcaaaaga tattgaaatc cgtgtggaag gtactgaagt aactcttcac
    27121 cgtccaaacg attcaaaaga aatgaaaact atccacggaa ctactcgtgc ccttttgaac
    27181 aacatggttg ttggtgtatc agaaggattc aagaaagaac ttgaaatgcg tggggttggt
    27241 taccgtgcac agcttcaagg atctaaactt gttttggctg ttggtaaatc tcatccagac
    27301 gaagttgaag ctccagaagg aattactttt gaacttccaa acccaacaac aatcgttgtt
    27361 agcggaattt caaaagaagt agttggtcaa acagctgctt acgtacgtag ccttcgttca
    27421 ccagaaccat ataaaggtaa aggtatccgt tacgttggtg aattcgttcg ccgtaaagaa
    27481 ggtaaaacag gtaaataatg ttgagtggtt gatcatcaac caccaaccta ttttccaact
    27541 ttgtgcatag cacacgattt aaaactaaag aggtgaaaac tgtgatttca aaaccagata
    27601 aaaacaaact ccgccaaaaa cgccaccgtc gcgttcgcgg aaaactctct ggaactgctg
    27661 atcgcccacg tttgaacgta ttccgttcta atacaggcat ctacgctcaa gtgattgatg
    27721 acgtagcggg tgtaacgctc gcaagtgctt caactcttga taaagaagtt tcaaaaggaa
    27781 ctaaaactga acaagccgtt gctgtcggta aactcgttgc agaacgtgca aacgctaaag
    27841 gtatttcaga agtggtgttc gaccgcggtg gatatctata tcacggacgt gtgaaagctt
    27901 tggctgatgc agctcgtgaa aacggattga aattctaata ggaggacact agaaaatggc
    27961 atttaaagac aatgcagttg aattagaaga acgcgtagtt gctgtcaacc gtgttacaaa
    28021 agttgttaaa ggtggacgtc gtcttcgttt cgcagctctt gttgttgttg gtgaccacaa
    28081 tggtcgcgta ggatttggta ctggtaaagc tcaagaagtt ccagaagcaa tccgtaaagc
    28141 agtagatgat gctaagaaaa acttgatcga agttcctatg gttggaacaa caatcccaca
    28201 cgaagttctt tcagaattcg gtggagctaa agtattgttg aaacctgctg tagaaggttc
    28261 tggagttgcc gctggtggtg cagttcgtgc cgttgtggaa ttggcaggtg tggcagatat
    28321 tacatctaaa tcacttggtt ctaacactcc aatcaacatt gttcgtgcaa ctgttgaagg
    28381 tttgaaacaa ttgaaacgcg ctgaagaaat tgctgccctt cgtggtattt cagtttctga
    28441 tttggcataa gaaaggggat aaaatggctc aaattaaaat tactttgact aagtctccaa
    28501 tcggacgcat tccatcacaa cgtaaaactg ttgtagcact tggacttggc aaattgaaca
    28561 gctctgttat taaagaagat aacgctgcta tccgtggtat gatcacagca gtatctcact
    28621 tagtaacagt tgaagaagta aactaatgaa gttttagggg atgtgcactg taccatcccc
    28681 taaaactaga tatagtcatc tatgatgaca tcgtataggc gagttgatgg gggagacaac
    28741 cttttctccc ttatcggcgc tagcatttta caaaagagga gaaaataaaa atgaaacttc
    28801 atgaattgaa acctgcagaa ggttctcgta aagtacgtaa ccgcgttggt cgtggtactt
    28861 catcaggtaa cggtaaaaca tctggtcgtg gtcaaaaagg tcaaaaagct cgtagcggtg
    28921 gcggagttcg ccttggtttt gaaggtggac aaactccatt gttccgtcgt cttccaaaac
    28981 gtggattcac taacatcaac gctaaagaat acgcaattgt gaaccttgac caattgaacg
    29041 tctttgaaga tggtgctgaa gtaactccag ttgttcttat cgaagcagga attgttaaag
    29101 ctgaaaagtc aggtattaaa attcttggta acggtgagtt gactaagaaa ttgactgtga
    29161 aagcagctaa attctctaaa tcagctgaag aagctatcac tgctaaaggt ggttcagtag
    29221 aagtcatcta agagaggtga cctatgtttt ttaaattatt aagagaagct cttaaagtca
    29281 agcaggttcg atcaaaaatt ttatttacaa tttttatcgt tttggtcttt cgtatcggaa
    29341 ctagcattac agttcctggt gtgaatgcca atagcttgaa tgctttaagt ggattatcct
    29401 tcttaaacat gttgagcttg gtgtcgggga atgccctaaa aaacttttcg atttttgccc
    29461 taggagttag tccctatatc accgcttcta ttgttgtcca actcttgcaa atggatattt
    29521 tacccaagtt tgtagagtgg ggtaaacaag gggaagtagg tcgaagaaaa ttgaatcaag
    29581 ctactcgtta tattgctcta gttctcgctt ttgtgcaatc tatcgggatt acagctggtt
    29641 ttaatacctt ggctggagct caattgatta aaactgcttt aactccacaa gtttttctga
    29701 cgattggtat catcttaaca gctggtagta tgattgtcac ttggttgggt gagcaaatta
    29761 cagataaggg atacggaaac ggtgtttcca tgattatctt tgccgggatt gtttcctcaa
    29821 ttccagagat gattcagggc atctatgtgg actactttgt gaacgtccca agtagccgta
    29881 tcacttcatc tatcattttc gtaatcattt tgattattac tgtattgttg attatttact
    29941 ttacaactta tgttcaacaa gcagaataca aaattccaat ccaatatact aaggttgcac
    30001 aaggtgctcc atctagctct taccttccgt taaaggtaaa ccctgctgga gttatccctg
    30061 ttatctttgc cagttcgatt actgcagcgc ctgcggctat tcttcagttt ttgagtgcca
    30121 caggtcatga ttgggcttgg gtaagggtag cacaagagat gctggcaact acttctccaa
    30181 ctggtattgc catgtatgct ttgttgatta ttctctttac attcttctat acgtttgtac
    30241 agattaatcc tgaaaaagca gcagagagcc tacaaaagag tggtgcctat atccatggag
    30301 ttcgtcctgg taaaggtaca gaagaatata tgtctaaact tcttcgtcgt cttgcaactg
    30361 ttggttccct cttccttggt gtgatttcca ttttaccgat tgcagctaaa gatgtatttg
    30421 gtctttctga tgttgttgcc tttggtggaa caagtctctt gatcattatc tctacaggta
    30481 tcgaaggaat caagcaattg gaaggttacc tattgaaacg taagtatgtt ggtttcatgg
    30541 acagaacaga ataaaagtat ttactgaatc agtaaatgct gagggagtgg aggtttaaac
    30601 tctgacattt gtaagagttg gatctcccct cttctatttt gtttttaaat aggggtgaaa
    30661 agactttttg cttctattta aaaataaaat aaggagatca aatcatgaat cttttgatta
    30721 tgggcttacc tggtgcaggt aagggaactc aagcagcaaa aatcgtagaa caattccatg
    30781 ttgcacatat ctcaacaggt gatatgttcc gcgctgcaat ggcaaatcaa actgaaatgg
    30841 gtgttcttgc taagtcatat attgacaagg gtgaattggt tcctgacgaa gttacaaatg
    30901 gaatcgtaaa agaacgtctt tcacaagatg atattaaaga aacaggattc ttattggatg
    30961 gttacccacg tacaattgaa caagctcatg ccttggacaa aacattgact gaacttggca
    31021 ttgaactaga aggtgttatc aatattgaag tgaaccctga cagccttttg gaacgtttga
    31081 gtggccgtat catccaccgc gtaactggag aaactttcca caaggtcttt aacccaccag
    31141 ttgactataa agaagaagat tactaccaac gtgaagatga taagcctgag acagtaaaac
    31201 gtcgtttgga tgttaatatt gctcaaggag aaccaatcat tgctcactac cgtgccaaag
    31261 gtttggttca tgacatcgaa ggtaatcaag atatcaatga tgtcttctca gatattgaaa
    31321 aagtattgac aaatttgaaa taaagcgttt ttcacacttg ccaaaatccg ctacaaatgt
    31381 tatactgaga tagtctgact tataattgtt gtctctgtgt ctagaggcat cgaatcgaaa
    31441 tttatggagg tgcttttgcg tggcaaaaga cgatgtgatt gaagttgaag gcaaagtagt
    31501 tgatacaatg ccgaatgcaa tgtttacggt tgaacttgaa aatggacatc agattttagc
    31561 aacagtttct ggtaaaattc gtaaaaacta tattcgtatt ttagcgggag atcgtgttac
    31621 tgtcgaaatg agtccatatg acttgacacg tggacgtatc acttaccgct ttaaataatc
    31681 gaaaaacttg gagggataag aaatgaaagt aagaccatcg gtcaaaccaa tttgcgaata
    31741 ctgtaaagtt attcgtcgta atggtcgtgt tatggtaatt tgcccagcaa atccaaaaca
    31801 caaacaacgt caaggataag atagaaagga gaaaacatgg ctcgtattgc tggagttgat
    31861 attccaaatg acaaacgcgt agtaatctca ttgacttatg tttatggtat cggacttgca
    31921 acatctaaga aaattttggc tgctgctgga atctcagaag atgttcgtgt acgtgatctt
    31981 acatcagatc aagaagatgc tatccgtcgt gaagtggatg caatcaaagt tgaaggtgac
    32041 cttcgtcgtg aagtaaactt gaacatcaaa cgtttgatgg aaatcggttc ataccgtggt
    32101 atccgtcacc gtcgtggact tcctgtccgt ggacaaaaca ctaaaaacaa cgctcgcact
    32161 cgtaaaggta aagctgttgc gattgctggt aagaaaaaat aatataggag gtaaaagtct
    32221 tggctaaacc aacacgtaaa cgtcgtgtga aaaagaatat cgaatctggt attgctcata
    32281 ttcacgctac atttaataac actattgtta tgattactga tgtgcatggt aatgcaattg
    32341 cttggtcatc agctggtgct cttggtttca aaggttctcg taaatctaca ccattcgctg
    32401 ctcaaatggc ttctgaagct gctgctaaat ctgcacaaga acacggtctt aaatcagttg
    32461 aagttactgt aaaaggtcca ggttctggtc gtgagtcagc tattcgtgcg cttgctgccg
    32521 ctggtcttga agtaacagca attcgtgatg tgactccagt gccacacaat ggtgctcgtc
    32581 ctccaaaacg tcgccgtgta taatcatcgc attacactgc ttttcgttta agagggagta
    32641 actaaatgat cgagtttgaa aaaccaaata taacaaaaat tgatgaaaat aaagattatg
    32701 gcaagtttgt aatcgaacca cttgaacgtg gctacggtac aactcttggt aactctcttc
    32761 gtcgtgtact tctagcttct ctaccaggag cagctgtgac atctatcaac attgatggtg
    32821 tgttacatga gtttgacaca gttccaggtg ttcgtgaaga cgtgatgcaa atcattctga
    32881 acattaaagg aattgcagtg aaatcgtacg ttgaagacga aaaaatcatc gaactggatg
    32941 ttgaaggtcc tgctgaagta acagctggtg acattttgac agatagcgat attgaaattg
    33001 taaatccaga tcattatctc tttacaattg gtgaaggttc ttctctaaaa gcgactatga
    33061 ctgttaacag tggtcgtgga tatgtacctg ctgatgaaaa taaaaaggat aatgcaccag
    33121 ttggaacact tgctgtagat tctatttata caccagttac aaaagtcaac tatcaagtgg
    33181 aacctgctcg tgtaggtagc aatgatggtt tcgacaaatt aacccttgaa atcttgacaa
    33241 atggaacaat tattccagaa gatgctttag ggctttcagc acgtattttg acagaacatc
    33301 ttgatttgtt tacaaatctt actgagattg ctaagtcaac tgaagtgatg aaagaagctg
    33361 atactgaatc tgacgaccgt attttagatc gtacgattga ggaactggat ttgtctgtgc
    33421 gttcatacaa ctgtttaaaa cgtgccggta tcaatactgt gcatgatttg acagaaaaat
    33481 ctgaagcaga gatgatgaaa gtacgaaatc ttggacgcaa gagtttggaa gaagtgaaac
    33541 tcaaactcat tgatttgggt cttggattaa aagataaata aaggaggaat acatggctta
    33601 ccgtaaacta ggacgcacta gctcacaacg taaagcaatg cttcgcgatt tgacaactga
    33661 ccttttgatc aacgaatcaa tcgtgacaac tgaagctcgt gctaaagaaa tccgtaaaac
    33721 tgttgaaaaa atgattactc taggtaaacg tggtgatttg catgcacgtc gtcaagcagc
    33781 tgctttcgta cgtaatgaaa tcgcatctga aaactatgat gaagcaactg ataagtacac
    33841 ttctactaca gcacttcaaa aattgttctc agaaatcgca cctcgttatg ctgaacgtaa
    33901 cggtggatac actcgtatcc ttaaaactga accacgtcgt ggtgatgcag cgccaatggc
    33961 gatcatcgaa ttagtataaa atcatcaatt ttgttgagtg ttatgatgat ggagtcttgt
    34021 gctcttagtc tagctctggt ctaccgctag gatttcggtc ctagcgggaa cactcatcat
    34081 aagttgggat agtagacgct tgtttacgaa attgtttttt tcttaagaac aacttcgtaa
    34141 gcaggcgttt ttgagtattt tcgttagaat tatgctatac tatttgaaaa gaatcctgtt
    34201 taatgttaag gtttcttatt ttaagaagaa ttggagttta cttatgaaag ccattataac
    34261 tgttgttggt aaagataaat ctggaattgt tgcaggtgtt tctggtaaaa ttgcagaatt
    34321 aggattgaat attgacgata tctctcaaac tgtcttggat gaatatttta cgatgatggc
    34381 tgttgtatct agtgatgaaa agcaagattt tacctatctt cgtaatgaat ttgaagcttt
    34441 tgggcaaact ttgaatgtaa aaatcaatat tcagagtgca gcgattttcg aagctatgta
    34501 taatatctag gaggtcatca tggatattag acaagttact gaaaccatcg ccatgattga
    34561 ggagcaaaac ttcgatatta gaaccattac catggggatt tctcttttgg actgtatcga
    34621 tccagatatc aatcgtgctg cggagaaaat ctatcaaaaa attacgacaa aggcggctaa
    34681 tttagtagct gttggtgatg aaattgcggc tgagttggga attcctatcg ttaataagcg
    34741 tgtatcggtg acacctattt ctctgattgg ggcagcgaca gatgcgacgg actacgtggt
    34801 tctggcaaaa gcgcttgata aggctgcgaa agagattggt gtggacttta ttggtggttt
    34861 ttctgcctta gtacaaaaag gttatcaaaa gggagatgag attctcatca attccattcc
    34921 tcgcgctttg actgagacgg ataaggtctg ctcgtcagtc aatatcggct caaccaagtc
    34981 tggtattaat atgacggctg tggcagatat gggacgaatt atcaaggaaa cggcaaatct
    35041 ttcagatatg ggagcggcca agttggttgt attcgctaat gctgttgagg acaatccatt
    35101 tatggcgggt gcctttcatg gtgttgggga agcagatgtt atcatcaatg tcggagtttc
    35161 tggtcctggt gtggtgaaac gtgctttgga aaaagttcgt ggacagagct ttgatgtagt
    35221 agccgaaaca gttaagaaaa ctgcctttaa aatcactcgt atcggtcaat tggttggtca
    35281 aatggccagt gagagactgg gtgtggagtt tggtattgtg gacttgagtt tggcaccaac
    35341 ccctgcggtt ggagactctg tggcacgtgt ccttgaggaa atggggctag aaacagttgg
    35401 cacgcatgga acgacagctg ccttggccct cttgaacgac caagttaaaa agggtggagt
    35461 gatggcctgt aaccaggtcg gtggtctatc tggtgccttt atccctgttt ctgaggatga
    35521 aggaatgatt gctgcagtgc aaaatggctc tcttaattta gaaaaactag aagctatgac
    35581 ggctatctgt tctgttggat tggatatgat tgccatccca gaagatacgc ctgctgaaac
    35641 tattgcggct atgattgcgg atgaagcagc aatcggtgtt atcaacatga aaacaacagc
    35701 tgttcgtatc attcccaaag gaagagaagg cgatatgatt gagtttggtg gtctattagg
    35761 aactgcaccc gttatgaagg ttaatggggc ttcgtctgtc gacttcatct ctcgcggtgg
    35821 acaaatccca gcaccaattc atagttttaa aaattaagaa aataggagaa attttaagtt
    35881 ctatttaaga ttagatgtgt atactataat cattaaataa agacctccta atattatttg
    35941 aaacagataa cactgaatta gtttgaattt gattttcatc taatatcttt atttaatgaa
    36001 ctcctaaact ttttcataat aatctccttc aaaagtcgcc tgtatgggtg gcttttattt
    36061 tatcattcat gatataatag aagcaaacgg aggacggaaa atggtaaaag tacgattgta
    36121 tttggtacgt catggcaaga ccatgtttaa cacgattggt cgcgcgcaag gttggagcga
    36181 tactccctta actgctgaag gtgaacgagg gattcaagag ttaggaatcg gtttgcgaga
    36241 atctgatcta cagtttgagc gcgcttattc gagtgattct ggtcgtacca ttcagaccat
    36301 gggaattatc cttgaagaac ttggcttgca ggggaaaatc ccttatcgca tggacaagcg
    36361 tatcagagaa tggtgtttcg gtagttttga tggagcctat gatggcgatc ttttcatggg
    36421 cattattcct cgtatcttta atgtggacca cgttcaccaa ttgtcttatg ctgaactggc
    36481 tgagggcttg gtagaggtcg atacagctgg ttgggctgaa ggctgggaaa aactcagtgg
    36541 ccgaatcaag gaaggctttg aaatgattgc aaaagaaatg gaagatcaag gtggaggtaa
    36601 cgcccttgtt gtcagccatg gaatgactat tggaaccatt gtttatctga ttaatggcat
    36661 gcatccgcat ggtctagata atggtagcgt gacgattatt gaatatgagg acggtcagtt
    36721 tagggttgaa gttgtcggtg accgtagtta ccgagagcta ggacgtgaga agatggaaga
    36781 aggctctatt taatcagtct agacttgctt gccatgagct agggatttga taagaatatc
    36841 aagataagaa aaaacagccg agggtactcc tttcggctgt ttttgatgtg gaaaactaaa
    36901 gtgtaatgct attgctttta gagattttca taaacaagag caaggaacct actgttagaa
    36961 cagtcaggat agttgacaag gctgcggcta caccgtaatt tcctctgaga acctctgtat
    37021 aaatagctac agtcattgtt cttgttttga cattgtagag gaggatagaa gtagagagtt
    37081 ttgaaatcat tgtgacccaa gataagatgg ctccagaaat gataccagat agcatcattg
    37141 gagttgtaat cttagcaaag gtattgagac gactacttcc taagctttca gcagcttctt
    37201 caatacttgg tgctatttgt tgtaagctag caacagatga gcgaatagta tacggtaatc
    37261 ttctgacaga tagagacata atcaagatga aagcagtccc tgtaatcata agaaatccac
    37321 ttccaaatag accagtattg aaggaagaaa tgaaggcaat ccctagaacg gttcctggta
    37381 caatataagg taccatactg aggctgtcaa ttaagtttgt aaacaaattc cgttttctaa
    37441 cggctaggta ggagataaat gtcgcaaata gaacaactag aactaaggca atcaaaggga
    37501 tacgaatggt attgaaaata gcagatccca tacgattgaa agctagcttg taactgtttg
    37561 gagaataacc tttaaaaaat accatacctg atgtttttag gaaagaggta taaattaagt
    37621 agatttgagg taaaacagag ataaagataa ttccgtagac tgttgcataa atggcagtca
    37681 tttttccttt tgtagttttt ttaggcccaa ttggatggag cagattcatg ctgaaactgt
    37741 agcggtttgc aatgtgtttt tggataagga aaattgccaa ggcaatgata atcgccataa
    37801 ttgcaaaagc agaatttcct ccaacctcgc taataaattg ggtataaatc aggacaggga
    37861 aagtccgata tccttcgcca atcaacatag gcgttccaaa gtctgagaat gctctcataa
    37921 atacaagcaa ggagctgcta gtaaggttgg aactaggaga ggtaaaacaa ccgttacgat
    37981 aggtttaaat ccgaaggacc ccatgctttc agctgcttca agtagagaat tgtcaatact
    38041 gttcattgtt ccagcaacat atagaaatac cagtgggaat agttgcagtg taaagacaag
    38101 tataattcct ttgaatccat aaatatcgat agctggaaga taaagggcat ttgtcaaaaa
    38161 tttagtgatg acctcatttc gtcccagcaa gagaatccag gagtaggctc ctacgaaagg
    38221 agctgacatg gaagcaatga taatcaatat ttgtagaaat ttcttcccct tgaagtcata
    38281 catagagaag agataagcta atagggttcc tacaactaag gaagtgacag tagcggtaat
    38341 ggaaaccctg aaactgttga ctagtgtctc agagtagtag gctttactaa agaaagtgac
    38401 aaaattagct agtgagaatt atccttcatg tataagtgct tacttgagca cggtaacgat
    38461 aggataaacg agaaagacaa gataggtaag aaagatgaag aaagaggagg ctgtccaaat
    38521 atttagtttt ttacgttcca tggttgactc cttttatcag gttttgggaa ccatctgcag
    38581 aaaagatgtt taatttttgc gtattgattc gtagacgaat acgattgcct ttttgtagtt
    38641 cttcttcaaa agttgattct tcactaactt gaatttttga ggcaaaacct gtctcaatga
    38701 aatactccgt atttagtcca agatagacgc tatcgctaat agttccttca atatctccag
    38761 attcatcttt gataaactct tcgggacgaa tgcttacatg aatagcttgc tcctcaacct
    38821 gatcaagagc tggcattcga agggcatagc catctgaaaa gacgatataa gcgccgtcgc
    38881 tccgtttttc aagattagta gggataatat ttgtgcgttc gataaaggtt gccacaaact
    38941 cattagctgg tttatgatag agttcttttg gtcggccgat ttgttggatc accccatctt
    39001 tcataacagc aatttggtct gaaatagcca tggcttcttc ttggtcgtgg gttacataaa
    39061 cagttgtaat tcccacttcg tgttggattt ctcggatggc ttgacgcata tccaagcgaa
    39121 gtttggcctc cagattacta agtggctcgt ccatgaggag aacacttgga ttaaccgcta
    39181 aggcgcatgc caaggtgaca cgttgttgtt gtccaccact gagtttatcg ggctttcaat
    39241 ccgcatattg agcaatttgc atgagttcaa gatacttgtt ggtctgttga atcaattctt
    39301 cttttggaac cttcttttgc ataagaccaa aagcaacgtt gtctcggaca gtcaaatgtg
    39361 ggaaaatagc gtagttttgg aaaaccagcc cgatattgcg tttgctggat tccatattat
    39421 tgatttttgt atcatcgaag taaaattctc catctttgat actgttgaaa cctgcaatca
    39481 tacgaagaag ggtcgttttc ccacatcctg aagctccaag aagggtaaag agacttcctt
    39541 ttggaattgt aatgttcaaa ttctcaataa cagggacatc gtggtagatt tttttggcgt
    39601 taataatttc gatctcactc atagtgaacc tcttttactg tttagattgg atatctgtaa
    39661 agacttcgtt gtatttctta acgatatctg atttattctt gatgacataa tcataatctt
    39721 cagtgagtgt tttgattttg tcaattggtt tcatgttttc gcttgtttta gcatttttac
    39781 gaacaggacg gttagtagtg gttgtaccaa gtgtatcttg tacttcttga gagataataa
    39841 aatcgataaa tttcttggca ttttccatat ttttagcttt tttaacgata gtagcactag
    39901 caggtaggaa gacggttcct tcttttggat agactacttt aatgttagct ccgtcattta
    39961 agagtttaac tgctggatcc tcataagaga gaccaacagc catttctcca tcaacgactg
    40021 ctttatagac accagatgaa cttgaaccga ttttatagtg tattgaaact agaatagtac
    40081 acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgattaa tttgtcctgt
    40141 tcttatttca ttttactata ccatcaataa gtgtgaaaag atcttttaca taagaccaag
    40201 ccttatcatc tttgtaacca ccttgagctt gtagcatatt tgttaattga gcaaaggcgc
    40261 tagaagagtt tgctgggtca gcagttgcga tttttccttt tagttcaggt ttgagaaggt
    40321 cgctatatcc ttcgatgttc atgcctttag ttaaatcagg gtggacgatt aaaacactac
    40381 catctagtgt ataaggagta gagaagccag ttgtgttttg atattctttg ataacattat
    40441 cattttcttt tgaaatatag ttttcaaaga gttctccgtg ggtagcatat tgtgtataag
    40501 aaccaccaaa ggtaacatca gctacaggaa cttctttttc tgactctagt tttttgaaaa
    40561 gttctccagt accagcttga atcagttcta ctttgatacc atatttttct tcaaaggcag
    40621 gaagagttgc tccaattaag ccctctgagt ttggtgaata aacgactagc gaaccgccgt
    40681 ctcctttatc agatgaactg tcatcggcag attcattaga agaacaagca gcataataca
    40741 tccatttctt tttcatgatg ggatatctcc gttgtgttat ttaagtttat tttaaaacaa
    40801 tgtaagcgtt tttaaaacct acaattctat tctatagtat attgaatcta taacagtaca
    40861 ctttaactgc taaaatattt ctataaatta atttgacttt cctgatagag atgttcacat
    40921 cttatttcaa ttcactatat tagagtaaaa ttctctacaa aaagaagaat agcctatttt
    40981 actattcttc cgagtgattt caatttcttt ggggaaatat ggagatactt tttaaatact
    41041 ttggcaaaat atttatagtc tgaaaatcca acttggtcag agatagcgct taaaggggag
    41101 ttgggagatt cagccatctt atctatagct tgtttcaggc gatattgtaa gatatattca
    41161 tttagagtca tggggaagtc ttctttgata accttatata gatgcttgtt atctgcaaat
    41221 atctagagca tttcaaggaa ataaactaga aataacaatt aatatggtgg ttcagaaata
    41281 ccttttgata atcaataaga tcttcaggat gaagtgcgtt gactccatcc atttcatatt
    41341 tccgatttaa taaacgatat ttgttttcac caaattgatg aaaagggagt agttgaactt
    41401 ggtcgatatt taatgagtta aatagagtag cgaatttttc tgcatcctct aaactattgt
    41461 taaaattagg aataactggg attcttaaaa cgatagtttt attttgagaa aaagcataat
    41521 gaatgttttt aataatcatt tgattaaaaa ccccagtcac ttttttatgt tttatagaat
    41581 tataatgttt taggtctgtg tagataaaat ccacatattg aattaaatcg ataaattttt
    41641 catgatcaac aaaggcagta gtttcaatgg cagtgtgtat gtgatgttct ttagctgatt
    41701 ttaagatggc tttagcaaat tcaaactgag caaatatttc acctcctgat aaagttaaac
    41761 ctccaccgga ttcttcgtaa aattctttgt cttttaatac ctctgtaata atttcttcta
    41821 cagtcttttc ttcaccgact aaggtgaatt tctctcgttg agcatctttc attttttcag
    41881 gtttcattct ttgagattca ggattagaac accatggaca gcgcagagga catcctttta
    41941 aaaaaacagt tgtacgaata cccgggccgt catgaattga aaagtgttga atattaaaaa
    42001 taattccttt agatatttcc ataagagttc ctcctcttca taagtctatc ctatcacaaa
    42061 aacgaaagaa aaacaattac gaacgaaagg ttgatttgtt gttttttgct ttttattttg
    42121 gtagaataaa acggaggtgt aaaatgaaaa gattggaaca aattattaaa ttagtatcag
    42181 aatatgaaaa gatcgacgtt aatacattat cggaaaaatt aaatgtatcg aaagtaacga
    42241 ttagaaaaga tttagataaa ttagagtcaa aaggtttatt acacagagag catggatatg
    42301 ctgtattaaa tagtggagat gacttaaatg tacgtttgtc aattaattat gaaattaaga
    42361 gaaaaattgt tcaggaagca gtaaaattgg tgtcagataa tgaaacaata atgatagaat
    42421 ctggatcgac ctgtgcttta cttgctgagg aaatttgcaa gcaaaaaaga aatgttacga
    42481 ttgtaacaaa ttcatttttt atagcaaatt ttgtgagagc ttatgattca tgtcgtatta
    42541 ttgttcttgg tggagagttt cagaaggatt cacaggttac tgtgggacct ttattaaaag
    42601 aaatgataca gacttttcat gtgcatcaag cttttgttgg gacagatggt tacgataaag
    42661 agatgggctt tacaggaaaa gatttaatgc gcagtgaggt agttcaatat atttcagcag
    42721 cgtcggataa agtcattgta ctaactgact caagtaaatt tgataaaagg ggtacagtaa
    42781 gaagatttgc tttaagtcaa gtctatgaag taataacaga cgaaaaactt tctaaacaaa
    42841 atatagctac attagaaaat gctgggataa tggttaaggt agtttcgtaa gaggttaagt
    42901 gtatgaatca agataggaat aaactgctct ctaaaattgc ttatctgtat tatattgaaa
    42961 acttaaatca gtcacaaata gcagcaaaat taggaattta tagaacctct attagtagaa
    43021 tgttaacaga agcaaggaat gcaggaattg ttaaaattga aatagagaat tttgatacaa
    43081 atatgtttaa gttggaaaat tatgtaaaag aaaaatatgg tctggaaagt ttagaaatta
    43141 ttccaaatga atttgatgat aatccaacaa ttttatctga aagaatttct caagttgcag
    43201 caggtgtcct taggaattta attgatgata atatgaaaat tggcttttct tgggggaaaa
    43261 gtttaagtaa tttagtagat ttaattcaca gtaaaagtgt ccgaaatgtt cacttctatc
    43321 ctctagcagg tggtcctagt cacatacatg ctaaatacca tgtgaataca ctgatttatg
    43381 aaatgtctag aaaatttcat ggagagtgta catttatgaa tgcaacgatt gtgcaagaaa
    43441 ataaattgtt agcagatggt attttgcaat caagatattt tgaaaatttg aaaaatagtt
    43501 ggaaagattt agatatagct gtagtcggaa ttggtgattt tagcaataaa ggaaaacatc
    43561 aatggttaga catgcttaca gaggatgact ttaaagaatt gaccaaagtt aaaactgtag
    43621 gagaaatttg ttgtcgattt tttgattcaa aaggtaaaga agtctatgaa aacttacagg
    43681 aaagaacgat agcaatctct ttggaagatt taaaaaatat tcctcaaagt ttagctgttg
    43741 cttacggtga tacgaaagta tcttcgattc tttctgtctt gcgtgctaat ttagtaaatc
    43801 atttgattac agacaaaaat acaattttaa aagttttgga agaagatggg gatttgactt
    43861 ttagagagat tctaggtgag tgaaaatgat agactgattc agtttatcgt ttttcttttt
    43921 agttgattgc acatttgtgc ttatataaac aaaaatagtt tatctgttgt ttttggattg
    43981 acaactttat tatgtagttg tattctatag ttacaaaaga aaattttaaa atttcaaatg
    44041 aaaaaagctt tttacatagt gaaatgagga ggaatttatg gaaattattg ttccagatca
    44101 aattatcatg ggtttaattt tatatgctgg tgatgcgaaa caacatattt ataaagcgtt
    44161 agattacata aaaaatggta catgtgaacg gtgtgaagaa gaaatacagt tagctgatgc
    44221 agccttatta gaagctcata atctacaaac aaaatttttg gcacaggaag cgtctggtac
    44281 aaagacagaa attacagctc tctttgttca ttcacaagat catctcatga ccagtatgac
    44341 ggagattaat ttaatcaaag aaattattag tttgagaaaa gaacttcata aaaaataata
    44401 ctagagtatt atcattgtta ttaacataga ggaggaaaac ataatggtga agattggttt
    44461 gttttgtgca gcaggttttt ctactggtat gcttgtaaat aatatgaaaa ttgcagcgca
    44521 atctagtgga gttgagacag aaatagaggc gttttctcag tctaaattag cggattatgc
    44581 gccaaatata gatgttgcac tattgggtcc acaagttgct tatacattag ataaatcaaa
    44641 agaaatttgt gataagtgtg atgttccgat agctgttatt ccgatgatgg actatggtat
    44701 gttagatggg aaaaaagtat tagatttggc cctatctttg attagtgggt aagaaaagga
    44761 gatttattat gtcaaagatg gatgttcaga aaatcattgc accgatgatg aagtttgtga
    44821 atatgcgtgg cattatagct ctaaaagatg ggatgttagc aattttgcca ttgacagtag
    44881 ttggtagttt attcttgatt atgggacaat tgccgttcga aggattaaat aagagcattg
    44941 ctagtgtttt tggagctaat tggacagagc cgtttatgca agtatattca ggaacttttg
    45001 ctattatggg tctaatttct tgtttttcaa ttgcctattc ttatgctaag aatagcggag
    45061 tagaggcttt accagctgga gttctatctg tatctgcatt ctttattttg ctaagatcat
    45121 cttatatccc taaacaaggt gaggcgattg gggacgctat tagtaaagtt tggtttggag
    45181 gccaaggaat tattggtgct atcattatag gtttggtagt aggaagtatt tataccttct
    45241 ttataaagag aaaaattgtt attaagatgc cagaacaagt tccacaagct attgccaaac
    45301 agtttgaagc aatgattcca gcatttgtaa ttttcttatc ttctatgatt gtatatattt
    45361 tagcgaagtc aatgactaat ggcggaacat tcatagaaat gatttattct gctattcaag
    45421 ttccgttgca aggtttaact ggatctttgt atggtgctat tggaattgca ttctttatat
    45481 catttttgtg gtggtttggt gttcatgggc aatcggtagt aaatggagta gtgacagctc
    45541 tgcttttatc taatcttgat gctaataaag ctatgttagc ctctggtaat ctatcattag
    45601 aaaatggagc acatattgtt actcaacagt ttttagattc atttttaatt ctatcaggtt
    45661 cagggattac gtttggtctt gtagttgcca tgctttttgt agcaaaatca aaacaatacc
    45721 aagccttagg aaaagttgca gcttttccag caatatttaa cgtaaatgag ccagttgtat
    45781 ttggatttcc gattgtcatg aatccagtta tgtttgtacc tttcattctt gttcctgtac
    45841 ttgcagctgt gatagtatat ggagctattg caacaggttt catgcagcca ttctcagggg
    45901 taacattgcc ttggagtaca ccagctattc tatcaggatt tttggtgggt ggatggcaag
    45961 gtgttgtgac tcagctggtg atattagcga tgtctacatt ggtttatttt ccattcttta
    46021 aagtacagga tcgtttagct taccaaaatg aaatcaaaca atcttagagg tatttgtgtg
    46081 ttactgttaa actcacacat ttgtgctaaa aattagagag ttaaaatttt tctagttaaa
    46141 agcttgaaaa tttctataaa aatcggtatt atattttcga aagaaataaa aatattttcg
    46201 aaagaaaggt ggttacgatg gtaaatacag aagtagcaag aacaacaatc aagacagaat
    46261 attttggcag ccttactgaa aggatgaaca aatatcgaga agatgtttta aataaaaaac
    46321 cttatattga tgctgagaga gcagttctag caacacgcgc ctatgaacga tacaaggaac
    46381 aacctaatgt cctaaaacgt gcatatatgc tgaaagaaat tttggaaaat atgactatct
    46441 atattgaaga agaatctatg attgcgggaa atcaagcttc ttccaataaa gatgctccta
    46501 tttttccgga atatacgcta gaatttgttc tcaatgagtt ggatcttttt gaaaagcgtg
    46561 atggagatgt tttctatatt acagaagaaa caaaagaaca acttagaagt attgctccgt
    46621 tttgggaaaa taataattta cgtgctagag ctggtgcctt attacctgaa gaagtgtctg
    46681 tttatatgga aacaggattc ttcggtatgg aaggtaagat gaattctgga gatgctcacc
    46741 tagcagttaa ctatcagaaa cttttgcaat ttggcttaag aggttttgaa gagcgggctc
    46801 gtaaagcaaa agcagctcta gatttaacag atccagcaag tattgataaa tatcattttt
    46861 acgactctat atttatcgta atcgatgcta ttaaagtata tgcaaagcgc tttgttgctc
    46921 ttgctaaaag tttagccgaa aatgcaaatc ctaaacgtaa gaaagaatta cttgagattg
    46981 cagatatttg ctctagagtc ccatatgaac cggcaactac ttttgcagaa gctattcaat
    47041 cagtttggtt tattcaatgt attttacaaa ttgaatctaa tggccactct ctttcatatg
    47101 gccgttttga tcaatatatg tatccatata tgaaggctga tttagaaagt ggtaaagaaa
    47161 cagaagatag cattgttgaa cgtctgacaa atctttggat taagacaatt acaattaata
    47221 aggttcgcag tcaatcacat acattttctt cagcaggaag tcctttatat caaaatgtta
    47281 caattggtgg acagactcga gataagaagg atgctgttaa cccattatct tatttggtat
    47341 taaaatcagt tgcacaaacc catctaccgc aacctaatct aactgtacgt taccatgcag
    47401 gtttagatgc tcgtttcatg aatgagtgta ttgaagtgat gaaacttggt tttggtatgc
    47461 ctgcatttaa taatgatgag attattattc cttcttttat tgcaaaagga gtattggaag
    47521 atgatgctta tgattacagt gctattggat gtgttgaaac ggcagttcca gggaaatggg
    47581 gctatcgttg cacaggtatg agttatatga acttccctaa ggttctactt atcacgatga
    47641 atgatggaat tgatccggct tcgggtaaac ggtttgcacc aagctttggt cattttaagg
    47701 atatgaagaa cttttctgaa ttagaaaatg cttgggataa aacactaaga tatttgacac
    47761 gaatgagtgt tattgttgaa aattctattg atttatcatt ggaacgagaa gttcctgata
    47821 ttctatgttc agcattgact gatgattgta ttggtcgtgg aaaacacctt aaagaaggtg
    47881 gagcagtata tgattatata tcaggattgc aagttggaat tgcaaatttg tcggattcat
    47941 tagctgcaat taaaaaattg gtgtttgagg aagaacgtat aagcccaagt cagctttggc
    48001 atgcactgga aacagattat gccggagaag aaggtaaggt cattcaagaa atgttgattc
    48061 atgatgcacc taagtatggt aatgatgatg attatgctga caaattggtt actgctgctt
    48121 atgacattta tgttgatgaa attgctaaat atcctaatac acgttatgga agagggccta
    48181 ttggaggaat tcgttattca ggaacatctt ctatctcagc caacgtaggg cagggacgtg
    48241 gaacattagc aactccagat ggacgcaacg cgggtacacc gttagcagag ggttgttcac
    48301 catcacataa tatggatcaa cacggcccta catctgtttt aaaatctgtt tcaaaattac
    48361 caacagatga aatcgtaggt ggggttctct taaatcagaa agtaaatcct caaacgttag
    48421 ccaaagaaga agataaatta aaactaattg ctttgttacg aacattcttt aatcgtttac
    48481 atgggtacca tattcaatac aatgttgttt ccagagagac gctgattgac gctcagaaac
    48541 atcctgaaaa acacagagac ttaattgttc gtgttgcagg atactctgca ttcttcaatg
    48601 ttctttctaa ggcaacccaa gatgacatta taggacgtac tgagcatact ttgtaaaata
    48661 aagaggttct ttttatggaa tttatgcttg acacattaaa tttagatgag attaaaaagt
    48721 ggtctgaaat tttgccgcta gctggggtaa cttcaaatcc cactattgca aaaagagagg
    48781 gttctattaa tttttttgaa cgaatcaaag atgtaagaga attgattggc tctacaccct
    48841 ctattcatgt tcaggtgatt tctcaagatt ttgaaggcat cttaaaggat gctcataaaa
    48901 ttcgaagaca agcaggagat gatatattta tcaaagtacc tgttactcca gctggattac
    48961 gtgcaataaa ggcgctaaaa aaagagggct accatatcac tgcaacagct atttatacag
    49021 ttattcaggg attattagct atcgaagcag gagcggatta cctagctcca tattataata
    49081 gaatggaaaa tctgaacatt gattcaaatt ctgtcattcg tcaattagct cttgctattg
    49141 atagacagaa ctctcctagt aagattttag ctgcatcctt taaaaatgta gcacaagtaa
    49201 ataatgcttt agctgcaggt gcgcatgctg ttacagcagg agcagatgtt tttgaatcag
    49261 ctttcgccat gccatctatc caaaaggcgg ttgatgattt ttctgacgat tggtttgtta
    49321 ctcaaaatag tcgttccatt tagatagaga ggaaatacat atgagaattt ttgctagtcc
    49381 ttctagatat attcaggggg aaaatgcctt gtttgaaaat gccaaatcaa ttttggattt
    49441 gggaaattac ccgattctat tatgcgatca gttggtttat gatattgttg gaaaacgatt
    49501 tgaagattat ctacataggt atggtttcca tattgttctg gcgctattta atggtgaagc
    49561 ttctgacaat gaaatcaatc gagttgttgc cttggctgag aaagaaaatt gtgatagtat
    49621 tatcggtctt ggtgggggaa agacgattga tagcgcaaaa gctattgcag atttgattga
    49681 aaagcctgtt attattgctc caacaattgc atcgaccgac gcacctgtat ctgctttatc
    49741 tgttatttat acagatgaag gtgcatttga tcattatcta ttttattcta aaaatccaga
    49801 tttagttttg gttgatacaa aagttatttc acaagcccct aagcgtttat tagcgtctgg
    49861 tattgcagat ggtttagcaa cttgggttga ggcgcgtgcg gttatgcagg caaatggaaa
    49921 aactatgttg ggacaacagc aaacattggc tggagttgca attgcgaaga aatgtgaaga
    49981 aacgctgttt gcagatggtt tacaggctat ggcagcttgt gaagctaaag tggtgacacc
    50041 agcattagaa aatattgttg aagctaatac tttattgagt ggcctaggtt ttgaaagtgg
    50101 aggattagct gcggcgcatg caattcataa tggttttact gcattgacag gcgacattca
    50161 tcatttaaca catggtgaaa aagtagctta tggaacttta gtacaactat tattggaaaa
    50221 tagacctaaa gaagaacttg ataagtatat tgagttttac aaaaaaattg gtatgccaac
    50281 aactctaaaa gaaatgcatt tggatcaagt tggatatgat gatttaataa aagttggtaa
    50341 acaagcaact atggagggtg agacaattca tcagatgccg tttaagattt cgccttcaga
    50401 tgttgctcaa gctattatcg ctgtagatgc ctatgtaaat tcaaaataaa caataaggac
    50461 tactgttttc caaatggtag tcttttattg atcctcgtat tgaattctat agcagattga
    50521 aataagatga gaacaaatcg attgggaaag taaaattaat ttctataaat gttttagcaa
    50581 ttgtttcgta ctatttcaga ttcagtccac tatacgttct tcataaatca aaaagcgaca
    50641 taggttgtcg gctatttatt gtgaatacat taattagcat tccagtttta tcttcggtct
    50701 aaaataagta ttttgtgcta tacgagataa gtttcttgac ttactccttg atttactgca
    50761 taacaatggg ataaaaagtg ggagatagag caattcatag tcatcaaaat taatgagata
    50821 cagtatacag ttttttcttt aaacacattt caaattccct caaaaatggt ataatagtaa
    50881 catcacaaaa ttggagagag accatgagtt tttacaatca taaagaaatt gaacctaagt
    50941 ggcagggcta ctgggcagaa catcatacat ttaagacagg aacagatgca tcaaaaccta
    51001 agttttatgc gcttgatatg ttcccttatc cgtctggagc tggtctgcat gtaggacacc
    51061 cagaaggtta tactgcaacc gatatcctca gtcgttacaa acgtgcgcaa ggctacaatg
    51121 tccttcaccc aatgggttgg gatgcttttg gtttgcctgc agagcaatac gctatggata
    51181 ctggtaatga cccagcagaa tttacatcgg aaaacattgc caacttcaaa cgtcaaatca
    51241 atgcgcttgg attttcttat gactgggatc gtgaagtcaa cacaacagat ccaaactact
    51301 acaagtggac tcaatggatt ttcaccaagc tttacgaaaa aggcttggcc tatgaagctg
    51361 aagtgccagt aaactgggtt gaggaattgg gaactgccat tgccaatgaa gaagtgcttc
    51421 ctgacggaac ttctgagcgt ggaggctatc cagttgtccg caaaccaatg cgccaatgga
    51481 tgctcaaaat cacggcttac gcagagcgct tgctcaatga cttagatgaa ctagattggt
    51541 cagagtctat caaggatatg caacgtaact ggattggtaa atcaactggt gccaatgtaa
    51601 ctttcaaagt aaaaggaaca gacaaggaat ttacagtctt tactactcgt ccggacacac
    51661 ttttcggtgc gactttcact gtcttggctc ctgaacatga attagtagac gctatcacaa
    51721 gtccagagca agcagaagct gtagcagact ataaacacca agccagcctt aagtctgact
    51781 tggctcgtac agaccttgct aaagaaaaaa caggggtttg gactggtgct tatgccatca
    51841 accctgtcaa tggtaaggaa atgccaatct ggattgcgga ctatgttctt gctagttatg
    51901 gaacaggtgc ggttatggct gtgcctgctc acgaccaacg tgactgggaa tttgccaaac
    51961 aatttgacct ttcaatcgtc gaagtacttg aaggtggaaa tgtcgaagaa gctgcctaca
    52021 cagaggatgg cctgcatgtc aattcagact tcctagatgg attgaacaaa gaagacgcta
    52081 ttgccaagat tgtggcttac ttggaagaaa aaggctgtgg tcaggagaag gttacctacc
    52141 gtctccgcga ctggctcttt agccgtcaac gttactgggg tgaaccaatt ccaatcattc
    52201 attgggaaga tggaacttca acagctgttc ctgaaactga attgccgctt gtcttgcctg
    52261 taaccaagga tatccgtcct tcaggtaccg gtgaaagtcc actagctaac ttgacagatt
    52321 ggcttgaagt gactcgtgaa gatggtgtca aaggtcgtcg tgaaactaac accatgccac
    52381 aatgggcagg ttcaagctgg tactacctcc gctatattga tccacacaat actgagaaat
    52441 tggctgatga ggacctcctc aaacaatggt tgccagtaga tatctacgtg ggtggtgcag
    52501 agcatgctgt tcttcacttg ctttacgctc gtttctggca caaattcctc tatgacctcg
    52561 gtgttgttcc gactaaggaa ccattccaaa aactctttaa ccaagggatg attttgggaa
    52621 caagctaccg tgaccaccgt ggtgctcttg tggcaaccga caaggttgaa aaacgtgatg
    52681 gttccttctt ccatgtagaa acaggggaag agttggagca agcgccagcc aagatgtcta
    52741 aatcgctcaa gaacgttgtt aacccagacg atgtggtgga acaatacggt gccgataccc
    52801 ttcgtgttta tgaaatgttt atgggaccac tcgatgcttc gattgcttgg tcagaagaag
    52861 gtttggaagg aagccgtaag ttccttgacc gagtttaccg tttgattaca agtaaagaaa
    52921 tccttgcgga aaacaatggt gctcttgaca aggtttacaa cgaaacagtc aaagctgtta
    52981 ctgagcaaat tgagtctctc aaattcaaca cagctattgc ccaacttatg gtctttgtca
    53041 atgctgctaa caaggaagat aagctttatg ttgactatgc caaaggcttt attcaattga
    53101 ttgcaccatt tgcacctcac ttggcagaag aactctggca aacagtcgca gaaacaggtg
    53161 agtcaatctc ttatgtagct tggccaactt gggacgaaag caaattggtt gaagatgaaa
    53221 ttgaaattgt cgtccaaatc aaaggaaaag tccgtgccaa actcatggtt gctaaagatc
    53281 tatcacgtga agaattacaa gaaatcgctt tagctgatga aaaagtcaaa gcagaaattg
    53341 acggtaagga aatcgtgaaa gtaattgcgg taccgaataa actcgttaat atcgtcgtta
    53401 aataacgagt ttattagctc tatctgccac cttcaatagt ccactggact attgaagcca
    53461 actaaattag ttaacattgt tgtgaaataa gataggaatc cttcagagta gaatctggag
    53521 gattttttga atcttcttat gaaagtagga tatatagtag actgaatcta aaatagtacg
    53581 aaacaattgc taaaacattt atagaaatta attttacttt cccaatcgat ttgttctcat
    53641 cttatttcaa tacgctatac tatgggcaac tataaagttt gaaaagcgaa acaaggagaa
    53701 agttatacca gtaaacgaat atggtcagat gattggtgag tcaatggaag gttatacacc
    53761 aggtgagctg acttctattg atctcttaga agggcgttat gctaggatag aggctctttc
    53821 agtggaaaag catgcggagg atttgctagc tgtttatggt cctgatactc ctcaggagat
    53881 gtggacctac ctctttcagg agccagtagc agacatggag gaactggtca gccttttata
    53941 gcaaaatgaa ataagaacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg
    54001 ttttagaagt ataagtgtac tatttcagtt tcaatctact ataaatcaga tgttggctcg
    54061 taaggaccgt ttttactatg caatcataga caaggcaact ggtaaggctt tgggaacttt
    54121 ttctctcatg cgtattggcc agtaacggag taatagaagt gggagctgtt actttttctc
    54181 caaaactcag ggggacacgg atagggacag aagcccaata tctactggct cgctatgtct
    54241 ttgaagagct taactatcgt cgttatgagt ggaaatgcga tgctcttaac ctgccatcca
    54301 gacgtgctgc ggagcgtttg ggctttattt atgaaggaac cttccgtcag gcagtggttt
    54361 ataaggggcg tacgagagat acggattggt tgtctatgat tgataaggac tggcccaaag
    54421 tcaaagatcg tttggaaaca tggttgcgtc ctgaaaattt tgataaaaat ggacagcagt
    54481 acaagagctt gagagagttt taagaggtgt tgacatgatc actattagaa agcaagaaat
    54541 cgtcaagttc gaggatgttt tgcatctcta tcaggctgtc ggttggacaa attatacaaa
    54601 tcaacctcag atgctggagc aggccttgta tcattcatta gtaatttatc tggcacttga
    54661 tggtgatgct gttgtgggct tgattcgttt ggctggagat ggtttttcat cagtttttgt
    54721 acaggatttg attgttttgt ctagctatca gcgccaaggg attggtagct ccttgatgaa
    54781 acaggcttta ggaaatttta aagaggccta tcaagtccag ctggcgacag aacagacaga
    54841 aaaaacgtgg gatttaatcg ttctatgggc tttgaaatct tatccaccta taattggata
    54901 gggatgactt ggatgaatcg taaaaaataa caaaacttgt tttttcttaa gcaaaattta
    54961 aggatggtct agtattatat aatcattaaa taaagacctc ctaactttat ttaataaaat
    55021 cctaaacttt tctttttcat aataatctcc cttaactcca cccaatcagg tggagttttt
    55081 tagctctatt tcaggctttt ggggactatt ctaaaaataa tttttcgata tttttcgata
    55141 tttttcggta tttttcggat tttggtcggg gaattggcgg ggattttttt agcgaatatg
    55201 actaagaaat aggcctgtgg tcgcttcagt tagttcaaac tcaatttgat tgtaagtgac
    55261 tgttaattga aggactggaa ctactgtaat aatgattttg cttgtctagt agtggcgtat
    55321 taaatgagaa gtgacatgta agattgtctc ttcgtttacg aaatcaaaat ttctatgaaa
    55381 ttgatagaat ccctaacgtt ctcttaatct taaccgtctt gtcgtacagc ggttgaagaa
    55441 aatgtaaagt tttgacaaaa ttcgtgaact atgggataat aaaagggaat taagtattgt
    55501 atccatcatg gactatctca cctcctttcg caggcggtgt agcagtgtcg tagaatatta
    55561 taccacataa gtgctaaact taggagtcac ccaatcaggt ggcttttttg tttgtggctt
    55621 ggttttttga tataatagag ccatgagtag aattttagat aatgagataa tgggggatga
    55681 ggagttagta gaacgcacgc tccgtcctca gtatttacgt gaatatatcg gacaggataa
    55741 ggtcaaggac cagctacaaa tctttattga agctgccaaa atgcgggatg aagcgctgga
    55801 tcatgtgctc ttatttgggc ctccaggtct cgggaaaacg accatggcct ttgttattgc
    55861 caacgaactg ggagtcaatc ttaagcagac gtcgggtcca gtcattgaaa aagccggaga
    55921 tctggtagct attttgaatg agttagagcc tggggatgtc ctttttattg atgagatcca
    55981 tcgtttgcca atgtcagtgg aagaggtgct ttatagtgct atggaggact tctacataga
    56041 tattatgatt ggggctggtg agggtagtcg tagtgttcat ttggagttac caccttttac
    56101 cttgattggt gcgacgactc gggctggtat gctctccaat ccgctacggg cacgttttgg
    56161 gattacaggc catatggagt attatgccca tgctgacttg acagaaattg tcgagcggac
    56221 ggcagatatt tttgagatgg aaatcactca tgaggcagca tctgagttgg ccctacgtag
    56281 tcgtgggacc cctcgtattg ccaatcgtct cctcaagcgc gtgcgcgatt ttgcccagat
    56341 aatggggaat ggggtaattg atgatattat taccgataag gctttgacta tgctggatgt
    56401 tgaccatgaa ggtttggact atgtggatca aaaaatcctt cgtaccatga ttgagatgta
    56461 cagtggagga cctgttggtc taggaactct ttctgtgaat atcgccgaag agcgtgagac
    56521 agttgaagat atgtatgagc cttacttgat tcaaaaaggt tttatcatgc ggacacggtc
    56581 tggacgggtg gcgactgcta aggcatatga gcacttaggt tatgaataca gtgaaaaata
    56641 agcaagaaat cttagaggct tttagagaaa atccagatat gatggccatt ctgacgatca
    56701 tccgagacct tggtctgaaa gactcgtggt tggcagcagg ttctgtcaga aatttcattt
    56761 ggaatctttt gtcagacaaa tccccttttg atcatgaaac agatatagat gtgattttct
    56821 ttgatccaga tttttcttat gaggaaacct tattactgga gaaaaagctg agagaggatt
    56881 ttcctcagta ccagtgggaa ttgaaaaatc aggtctatat gcatcagcac agtcctcaca
    56941 ctgcttccta taccagttct cgtgatgcta tgagtaagta tccagaacgg tgtacggcag
    57001 ttggactgcg cttgaatgaa gaatccgctt tggaactctt tactccatac ggtctggagg
    57061 atattttgaa ttttcaagtt cgtccaactc ctcatttttt agagaatcaa gaacgaatgg
    57121 ctctctataa aacacgttta tccaagaaaa attggcagga gaaatggaaa aatttgattt
    57181 ttaaaaatac ttaaggaaac tttaagctag ggagtgtaca ctaagttcat aagttaagaa
    57241 gaccttaact taaactccta aaactttttc ataataatct ccctataaaa ataaagtcgc
    57301 ccaatcaggc ggcttatttt tttgaaaaat gggcttggtg cctgagaata aatagcttag
    57361 tgatagaaga aaatggggaa atatggtata atgaaacgat agatttttga ataggaataa
    57421 gatcatgttt ggatttttta agaaagataa ggctgtggaa gtagaggttc cgacacaggt
    57481 tcctgctcat atcggcatca tcatggatgg caatggccgt tgggctaaaa aacgtatgca
    57541 accgcgagtt tttggacata aggcgggcat ggaagcattg caaaccgtga ccaaggcagc
    57601 caacaaactg ggcgtcaagg ttattacggt ctatgctttt tctacggaaa actggacccg
    57661 tccagatcag gaagtcaagt ttatcatgaa cttgccagta gagttttatg ataattatgt
    57721 cccggaacta catgcgaata atgttaggat tcaaatgatt ggggagacag accgcctgcc
    57781 taagcaaacc tttgaagctt taaccaaggc tgaggaattg actaagaaca acacaggatt
    57841 gattcttaat tttgctctta actatggtgg acgtgctgag attacacagg cgcttaagtt
    57901 gatttcccag gatgttttag atgccaaaat caacccaggt gacatcacag aggaattgat
    57961 tggtaactat ctctttaccc agcatttgcc taaggactta cgagacccag acttgattat
    58021 ccgtactagt ggagaattac gtttgagcaa tttccttcca tggcagggag cctatagtga
    58081 gctttatttt acggacacct tatggcctga ttttgacgaa gcggccttgc aggaagctat
    58141 tcttgcctat aatcgtcgtc atcgccgatt tggaggagtt taggaggaaa tatgacccag
    58201 gatttacaga aaagaacctt gtttgcaggg attgccctgg ctattttcct accaatttta
    58261 atgattgggg gcctcttgct tcagatagca atcggaatca tagccatgct agccatgcat
    58321 gaacttttga agatgagagg tctagagacc atgacgatgg agggcctctt gaccctcttt
    58381 gcaacctttg cattgaccat tcccttggag aattacctga cttttttgcc agttgatggg
    58441 aatgtggttg cctatagtgt tttgatttca atcatgttag gaacgaccgt ttttagcaag
    58501 tcttatacga ttgaggatgc ggttttccct cttgctatga gcttctatgt gggctttgga
    58561 tttaatgctt tactagatgc tcgtgttgca ggtttggaca aggctctctt agccttgtgt
    58621 atcgtctggg cgacagacag tggtgcctat cttgttggga tgaactatgg gaaacgaaag
    58681 ttagcaccaa gggtatcgcc taataaaacc cttgagggtg ccttgggcgg tattttagga
    58741 gcaattttag taaccattat ctttatgata gttggcagta cagttgctct tccatatgga
    58801 atttacaaga tgtcagtctt tgctattttc tttagcattg ctggacaatt tggtgattta
    58861 ctagaaagtt cgatcaaacg tcattttggt gttaaggatt ctgggaaatt tatccctgga
    58921 catggtggtg ttttggatcg tttcgatagt atgttgcttg tatttccaat catgcactta
    58981 tttggactct tttaatcaaa agacggagga aacgctatgc tcggaatttt aacctttatt
    59041 ctggttttcg ggattattgt agtggtgcac gagttcgggc acttctactt tgccaagaaa
    59101 tcagggattt tagtacgtga atttgccatc ggtatgggac ctaaaatctt tgctcacatt
    59161 ggcaaggatg gaacggccta taccattcga atcttgcctc tgggtggcta tgtccgcatg
    59221 gccggttggg gtgatgatac aactgaaatc aagacaggaa cgcctgttag tttgacactt
    59281 gctgataatg gtaaggttaa acgcatcaat ctctcaggta aaaaattgga tcaaacagcc
    59341 ctccctatgc aggtgaccca gtttgatttt gaagacaagc tctttatcaa aggattggtt
    59401 ctagaagaag aaaaaacatt tgcagtggat cacgatgcaa cggttgtgga agcagatggt
    59461 actgaggttc ggattgcacc tttagatgtt caatatcaaa atgcgactat ctggggcaaa
    59521 ctgattacca attttgcagg tcctatgaac aattttatct taggtgtcgt tgttttttgg
    59581 gttttaatct ttatgcaggg tggtgtcaga gatgttgata ccaatcagtt ccatatcatg
    59641 ccccaaggtg ccttggccaa ggtaggagta ccagaaacgg cacaaattac caagattggc
    59701 tcacatgagg ttagcaactg ggaaagcttg atccaagctg tggaaacaga aaccaaagat
    59761 aagacggcac cgactttgga tgtgactatt tctgaaaagg ggagtgacaa acaagtcact
    59821 gttacacccg aagatagtca aggtcgttac cttctaggtg ttcaaccggg ggttaagtca
    59881 gattttctat ccatgtttgt aggtggtttt acaactgcta ctgactcagc tctccgaatt
    59941 ctctcagctc tgaaaaatct gattttccaa ccggatttga acaagttggg tggacctgtt
    60001 gctatcttta aggcaagtag tgatgctgct aaaaatggaa ttgagaatat cttgtacttc
    60061 ttggcaatga tttccatcaa tattgggatt tttaatctta ttccgattcc agccttggat
    60121 ggtggtaaga ttgtgctcaa tatcctagaa gccatccgcc gcaaaccatt gaaacaagaa
    60181 attgaaacct atgtcacctt ggccggagtg gtcatcatgg ttgtcttgat gattgctgtg
    60241 acttggaatg acattatgcg actctttttt agataatcga ggaatattat gaaacaaagt
    60301 aaaatgccta tcccaacgct tcgcgaaatg ccaagcgatg ctcaagttat cagccatgct
    60361 cttatgttgc gtgctggtta tgttcgccaa gtttcagcag gtgtttattc ttatctacca
    60421 cttgccaacc gtgtgattga aaaagctaaa aacatcatgc gccaagaatt cgaaaagatt
    60481 ggtgctgttg agatgttgac tccagccctt cttagtgcag aattgtggcg tgaatcaggt
    60541 cgttacgaaa cctatggtga agacctttac aaactaaaaa accgtgaaaa atcagacttt
    60601 atcttaggtc caactcacga agaaaccttt acagctattg tccgtgattc tgttaaatct
    60661 tacaagcaat tgccactcaa cctttatcaa attcagccca agtatcgtga tgaaaaacgc
    60721 ccacgtaatg gacttcttcg tacacgtgag tttatcatga aggatgctta tagtttccac
    60781 gctaactatg atagtttgga tagtgtttat gatgagtaca aagcagccta tgagcgtatt
    60841 ttcactcgta gtggtttaga cttcaaggct attattggtg acggtggagc catgggtggt
    60901 aaggatagcc aagaatttat ggccattaca tctgctcgta cagaccttga ccgctgggtt
    60961 gtcttggaca agtcagttgc ctcatttgac gaaattcctg cagaagtgca agaagaaatc
    61021 aaggcagaat tgctcaaatg gatagtctct ggtgaagata ccattgctta ctcaagtgag
    61081 tctagctatg cagctaactt agaaatggca acaaacgagt acaaaccaag caaccgtgtt
    61141 gtcgctgaag aagaagttac tcgtgttgca acgccagatg ttaaatcaat tgatgaagtt
    61201 gcagctttcc tcaatgttcc agaagaacaa acgattaaaa ccctcttcta cattgcagat
    61261 ggtgagcttg ttgcagccct tctagttgga aatgaccaac tcaacgaagt caagttgaaa
    61321 aaccacttag gagcagattt ctttgacgtt gctagcgaag aagaagtggc gaatgttgtt
    61381 caagcaggat ttggttcact tggaccagtt ggtttgccag agaatattaa aattattgca
    61441 gatcgtaagg tgcaagatgt tcgcaatgca gttgtcggtg ctaacgaaga tggctaccac
    61501 ttgactggtg tgaacccagg ccgtgatttt actgcagaat atgtggatat ccgtgaagtt
    61561 cgtgagggtg aaatttcccc agatggacaa ggtgtcctta actttgcgcg tggtattgag
    61621 atcggtcata ttttcaaact cggaactcgc tactcagcaa gcatgggagc agatgtcttg
    61681 gatgaaaatg gtcgtgctgt gccaatcatc atgggatgtt acggtatcgg tgtcagccgt
    61741 cttctttcag cagtgatgga gcaacacgct cgcctctttg ttaacaaaac gccaaaaggt
    61801 gaataccgtt acgcttgggg aatcaatttc cctaaagaat tggcaccatt tgatgtgcat
    61861 ttgattactg tcaatgtcaa ggatgaagaa gcgcaagcct tgacagaaaa acttgaagca
    61921 agcttgatgg gagctggtta tgaagtcttg acagatgacc gtaacgaacg tgtcggtgtt
    61981 aaatttagcg atagtgactt gattggtctt ccaatccgta tcactgttgg taaaaaagcg
    62041 gccgatggca ttgtagaagt taagatcaag gcaactggtg acaccattga ggttcatgca
    62101 gataacgtgc ttgaaacgct tgaaatccta agcaagaaat aaaaactata atcagaagaa
    62161 aaacaaggaa aaaatgtaac tagtttttac cttgtttttt ctgtataatg ggagaaatga
    62221 gtagataaag aggtaaatgt atgctaagat ttccaaagga ttttgtctgg ggatcctcta
    62281 cttctggacc gcagacagaa ggacgtgtag ctggtgacgg taagggagac aatctctggg
    62341 attactggtt ccaagtggag ccaaatcgtt actataatgg gattggttca gataagacat
    62401 cgacttttta tgaaaattgg gagcgggata ttgagctttt gttagagact ggtcacacag
    62461 cctttcggac ttctattcag tggtcacgga tttttccaca aggctgtgga aaagtcaaca
    62521 ctcaaggtgt ggatttttat cgtaaggtct ttgaggctat taaggctaaa ggaattcgtc
    62581 tgttagtcaa tctctatcat tttgatttac cttttgccct tcaagaggat ggtgatggtt
    62641 gggaaaataa ggcgacagtc tcagcctatg aagactatgc tcgtttttgt tttgagactt
    62701 atggagattt agtggatcaa tggattacct ttaacgagcc catcgttcct gtagaatttg
    62761 gttattttta tgatgcccat tatccacata aggtggatgc agaggcagct gttaaggtag
    62821 cctatcatac acaattggcc agcagccggg ctgttaaggc ttgccatgaa cttttgcctg
    62881 attccaagat tgggattgtc ctcaacttga caccggctta tccacgtagc cagcatcctg
    62941 ctgatgtcaa ggcagctcgt attgcggccc tttttcaggc ccaatctttc ttagatccat
    63001 ctgtcttggg gacttatcca caggagttgg tagaaatctt gcatgaacac ggtcttttac
    63061 ctgatgctac agaggaagag ttggaactca ttcgtgataa tacggtggac ttccttggtg
    63121 tgaactacta tcaacctttg cgtgttatgg ctcctcgatt tgctaagcat ccagatagtc
    63181 cactcttacc agaacatttt tacgagcctt atgtgatgcc tggacgtaaa atcaattctc
    63241 accgtggttg ggagatttat gagcaaggga tttatgacat cgcccaaaat atcaaggaaa
    63301 attatggcaa tattgagtgg atgttgactg agaatggtat gggtgttgaa ggggaagaaa
    63361 aattccgtca agatggaatg attcaagatg attaccgtat tgactttgta aaaggtcatc
    63421 ttcgtgaact tcaccgtgcc attgaagatg gtgccaactg taagggctac ttgatttgga
    63481 cctttattga ctgctggtca tggctcaaca gctataaaaa tcgctatggt ttggtcgaat
    63541 tagacttgga aacgcaagaa cgtcgtctga agaaatcagg ccactggttc aaagaattaa
    63601 gcgataataa tggattttaa aaaggactct gactgattat cccaatcggt cagagttttt
    63661 tgcttacagg agcttaattt gaactatacc aatttttact cttgacaagt gaaagaaaca
    63721 agtatatact gtttttgctg attctataaa agatgaatta gactatacca attttaagga
    63781 gaaagcacag cttgcctgtg tcgtatatac tatgtgtgga attgttggtg ttgttggaaa
    63841 cacaaatgca actgatattt tgattcaagg gcttgaaaag cttgaatacc gtggctatga
    63901 ttctgcggga atttttgtcc tagatggtac tgataaccat ttggtgaagg ctgttggtcg
    63961 tatcgcagaa ttgtctgcta agacagctgg tgttgaggga acaactggta tcggacatac
    64021 tcgttgggca actcatggga aaccaacgga agacaatgct cacccacacc gctctgagac
    64081 agaacgtttt gtcttggttc acaatggggt gattgaaaac taccttgaaa ttaaagaaga
    64141 ataccttgct gggcaccact tcaaagggca aacagatacg gaaatcgccg tacatttgat
    64201 tggaaaattt gcggaagaag acggtctctc agttcttgaa gcctttaaaa aagctcttca
    64261 tattatccgt ggttcatatg cctttgcctt gattgactct gaaaatccag atgtcatcta
    64321 tgtagcgaaa aacaaatctc cacttttgat tggtcttggg gaaggctaca atatggtctg
    64381 ctcagatgct atggctatga ttcgtgaaac caaccaatac atggaaattc atgaccaaga
    64441 gttggtaatc gtcaaggctg atagcgtgga agttcaagac tatgatggta acagtcgtga
    64501 acgtgctagc tatactgcgg aacttgactt gtcagatatc ggtaagggaa cttatcctta
    64561 ctacatgctt aaggaaattg atgagcaacc aactgttatg cgtaaactca ttcaagccta
    64621 cacggatgat gctggtcaag tagtggttga tcctgctatc attaaggctg ttcaagacgc
    64681 agaccgcatc tacatccttg cagctggaac atcttaccat gcaggatttg cttctaagaa
    64741 aatgttggaa gaattgacag atacaccagt tgaacttggc atctcatctg agtggggcta
    64801 cggtatgcca cttctcagca agaaaccact cttcatcttt atcagccaat ctggtgaaac
    64861 agcggatagt cgtcaagttt tggtcaaggc taatgaaatg ggaattccaa gcttaacagt
    64921 gacaaatgtt ccaggctcaa ccctctcacg tgaagccaac tataccatgc tccttcacgc
    64981 aggtcctgaa attgccgtgg catcaactaa agcctataca gcgcaaatcg cagcccttgc
    65041 cttccttgca aaagcagtcg gagaagcaaa tggtaatgct aaagcgcaag cctttgacct
    65101 gattcatgaa ttgtcaatcg tagctcagtc tatcgaatca actctttcag agaaagaaac
    65161 cattgaagcc aaggttcgtg aacttcttga aacaactcgt aacgcctttt acatcggacg
    65221 tggtcaagat tactacgtag ccatggaagc aagtctcaaa ctcaaagaga tttcttatat
    65281 ccagtgtgaa ggctttgctg caggagaact caagcacgga accattgcct tgattgaaga
    65341 aggaacgcct gttttggctc tcttgtcaga tccagttctt gccaatcata ctcgtggaaa
    65401 tatccaagag gtcgcagccc gtggtgccaa agtcctcact atcgcagaag agaatgtagc
    65461 caaagatacc gacgatatcg tccttacgac cgtacatcca tacctctcac caatttcaat
    65521 ggtcgtacca acgcaattag tcgcttactt tgcaaccctc caccgtggcc tcgatgtgga
    65581 caaaccacgt aaccttgcca agtcagtaac ggtagaataa gctaaaaaag tctagttatc
    65641 taggcttttt cttgtgagca aattggttgc ttgtactcaa gattcgtgtt agaataattt
    65701 ttcaaattga aggacagaga tagacaagga gaatcacaat ggtagaattg ggaatttcaa
    65761 catttgggga aataacggag cttgaaggga ctggacaaac ttacagtcat gctgaacgca
    65821 ttcgccagtt ggtggcagag attgagctgg ctgacaaggt tggtttggac gtatatggga
    65881 ttggcgagca ccatcgggcg gattttgcag tatcagcccc agagattgtc ctggccgctg
    65941 gggcagtcaa taccaagaaa atccgtttga ccagtgcagt cagcattctg tcaagcatgg
    66001 acccgattcg tttgttccaa cagtatgcca ctatcgatgc tttgtcaaat ggacgatcgg
    66061 agattatggc tggaaggggc tctttcacgg aatctttccc tctgtttggt tatgacttga
    66121 aagactacga ctctcttttt gatgagaaat tagacttgct tcagttagtc aatgaaaaga
    66181 ccaagttaga ctggcaaggt cgattgactc aaacgattgc tggtaaagaa gtttatcctc
    66241 gtccagttca ggacaaattg cccttgtgga tagctacagg tggtcatgtc gaatcaacag
    66301 tgaagattgc tcaggctggt ctaccgattg tatatgctat tattggtggt aatccacgtt
    66361 attttaaaaa gttgattcag gcttatcgtg agattggaag cgaagcgggc catgctgaca
    66421 aagacttgaa agtgggagcc cattcttggg ggtggattgc ggaagatggt gagcaggcgg
    66481 tgaaagatta tttccatccg actaagcaag tggtggatgc tatttccaaa gaccgtccgc
    66541 actggcagga attgcgttat gagcaatatt tggagcaggt agggtcaaat ggcgccatgt
    66601 ttgttggcaa tccagatcag gtggccgaaa aattgattcg catgatagag gatttaggat
    66661 tggaccgctt catgcttcat ctaccgcttg gttctatgcc tcatgaccag gttctgagag
    66721 ctattgaact cttcggaaca caagttgcac ccaaagtacg agcttatttt gctatgaaag
    66781 aggc
//
LOCUS       DAVDFK010000009        61934 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.09, whole genome shotgun sequence.
ACCESSION   DAVDFK010000009 DAVDFK010000000
VERSION     DAVDFK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61934
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.09"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            146..883
                     /locus_tag="VUR04_000690"
     CDS             146..883
                     /locus_tag="VUR04_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340627.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            880..2571
                     /locus_tag="VUR04_000691"
     CDS             880..2571
                     /locus_tag="VUR04_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5340628.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            2687..3250
                     /locus_tag="VUR04_000692"
     CDS             2687..3250
                     /locus_tag="VUR04_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET5340629.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALANRPKLIGGARAHYPQDAIRKS"
     gene            3272..9085
                     /locus_tag="VUR04_000693"
     CDS             3272..9085
                     /locus_tag="VUR04_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HET5340630.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLFLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPEKQPEAPEEEKA
                     VEETPKQEESTPDTKAEETVEPKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEQVGE
                     PVEPSEDEKAPVSPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKA
                     SSVSPTDYSTASYNALGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDALNVDKSEL
                     QEQLRVAEQKQQADYSAKTWREFKIAELQAKEINNQTTPLPKQSEIDAATKALQDALQ
                     ALAIDKTVLQNAINTANSKREEEYTAQTWKALEDALTAVNPVNEDETATQSKVDEATR
                     NLEEAINNLVLLTEKPVLTFIETDKKALEREVVAKYSLENQNKTKIKSITATLKKGET
                     VVSTVELIGDDVTNETISSAFKNLEYYKEYTLSTTMVYDRGDGDVTEILDNQPIQLDL
                     KKVELKNIKRTDLIKYENGKETNESLITTVPDDKRNYYLKITSKNQKTTLLAVKNIEE
                     TTVNGTPVYKVTAIADNLVSRTADNKFEEEYVHYIEKPKVHEDNVYYNFKELVEAIQN
                     DPSKEYRLGQSMSARNVVPNGKSYITKEFTGKLLSSEGKQFAITELEHPLFNVITNAT
                     INNVNFENVEIERSGQDNIASLANTMKGSSVITNVKITGTLSGRNNVAGFVNNMNDGT
                     RIENVAFFGKLHSTSGNGSHTGGIAGTNYRGIVRKAYVDATITGNKTRASLLVPKVDY
                     GLTLDHLIGTKALLTESVVKGKIDVSNPVEVGAIASKTWPVGTVSNSVSYAKIIRGEE
                     LFGSNDVDDSDYASAHIKDLYAVEGYSSGNRSFRKSKTFTKLTKEQADAKVTTFNITA
                     DKLESDLSPLAKLNEEKAYSSIQDYNAEYNQAYKNLEKLIPFYNKDYIVYQGNKLNKE
                     HHLNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDYFNLSSSSEGLSNVKEYTI
                     TDLGIKYTPNIVQKDNTTLVNDIKSILESVELQSQTMYQHLNRLGDYRVNAIKDLYLE
                     ESFTDVKENLTNLITKLVQNEEHQLNDSPAARQMIRDKVEKNKAALLLGLTYLNRYYG
                     VKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIKGSRTFDAFGQVLAKYTKS
                     GNLDAFLNYNRQLFTNIDNMNDWFIDATEDHVYIAERASEVEEIKNSKHRAFDNLKRS
                     HLRNTILPLLNIDKAHLYLISNYNAIAFGSAERLGKKSLEDIKDIVNKAADGYRNYYD
                     FWYRLASDNVKQRLLRDAVIPIWEGYNAPGGWVEKYGRYNTDKVYTPLREFFGPMDKY
                     YNYNGTGAYAAIYPNSDDIRTDVKYVHLEMVGEYGISVYTHETTHVNDRAIYLGGFGH
                     REGTDAEAYAQGMLQTPVTGSGFDEFGSLGINMVFKRKNDGNQWYITDPKTLKTREDI
                     NRYMRGYNDTLTLLDEIEAESVISQQNKDLNSAWFKKIDREYRDNNKLNQWDKIRNLS
                     QEEKNELNIQSVNDLVDQQLMTNRNPGNGIYKPEAISYNDQSPYVGVRMMTGIYGGNT
                     SKGAPGAVSFKHNAFRLWGYYGYENGFLGYASNKYKQQSKTDGESVLSDEYIIKKISN
                     NTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDDLLTLFKEAVKKDAETLKQ
                     EANGNKTVSMNNTVKLKEKVYKKLLQQTNSFKTSIFK"
     gene            9146..10867
                     /gene="pabB"
                     /locus_tag="VUR04_000694"
     CDS             9146..10867
                     /gene="pabB"
                     /locus_tag="VUR04_000694"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET5340631.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIRELKTRDLAEVADLLAQVENYQ
                     TQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAEDYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLGQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLEIGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            10868..11485
                     /locus_tag="VUR04_000695"
     CDS             10868..11485
                     /locus_tag="VUR04_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5340632.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            11535..12525
                     /locus_tag="VUR04_000696"
                     /pseudo
     CDS             11535..12525
                     /locus_tag="VUR04_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            12660..13619
                     /locus_tag="VUR04_000697"
     CDS             12660..13619
                     /locus_tag="VUR04_000697"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET5340633.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            13716..14555
                     /locus_tag="VUR04_000698"
     CDS             13716..14555
                     /locus_tag="VUR04_000698"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET5340634.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(14603..14773)
                     /locus_tag="VUR04_000699"
     CDS             complement(14603..14773)
                     /locus_tag="VUR04_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET5340635.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            14894..15778
                     /gene="miaA"
                     /locus_tag="VUR04_000700"
     CDS             14894..15778
                     /gene="miaA"
                     /locus_tag="VUR04_000700"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET5340636.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            15771..17009
                     /gene="hflX"
                     /locus_tag="VUR04_000701"
     CDS             15771..17009
                     /gene="hflX"
                     /locus_tag="VUR04_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET5340637.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            17002..17625
                     /locus_tag="VUR04_000702"
     CDS             17002..17625
                     /locus_tag="VUR04_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET5340638.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            17640..18569
                     /locus_tag="VUR04_000703"
     CDS             17640..18569
                     /locus_tag="VUR04_000703"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET5340639.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            18590..19345
                     /locus_tag="VUR04_000704"
     CDS             18590..19345
                     /locus_tag="VUR04_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET5340640.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(19399..20307)
                     /locus_tag="VUR04_000705"
     CDS             complement(19399..20307)
                     /locus_tag="VUR04_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET5340641.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            20371..20640
                     /locus_tag="VUR04_000706"
     CDS             20371..20640
                     /locus_tag="VUR04_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET5340642.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            20640..21020
                     /locus_tag="VUR04_000707"
     CDS             20640..21020
                     /locus_tag="VUR04_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5340643.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            21109..21336
                     /locus_tag="VUR04_000708"
     CDS             21109..21336
                     /locus_tag="VUR04_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340644.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVVIALIFR"
     gene            complement(21376..22101)
                     /locus_tag="VUR04_000709"
     CDS             complement(21376..22101)
                     /locus_tag="VUR04_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5340645.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            22263..24104
                     /gene="typA"
                     /locus_tag="VUR04_000710"
     CDS             22263..24104
                     /gene="typA"
                     /locus_tag="VUR04_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET5340646.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            24124..24378
                     /locus_tag="VUR04_000711"
     CDS             24124..24378
                     /locus_tag="VUR04_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET5340647.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKGKRR"
     gene            24743..25045
                     /locus_tag="VUR04_000712"
                     /pseudo
     CDS             24743..25045
                     /locus_tag="VUR04_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850385.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            25116..27137
                     /locus_tag="VUR04_000713"
                     /pseudo
     CDS             25116..27137
                     /locus_tag="VUR04_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            27139..27780
                     /locus_tag="VUR04_000714"
     CDS             27139..27780
                     /locus_tag="VUR04_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340648.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIENQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            27884..29236
                     /locus_tag="VUR04_000715"
     CDS             27884..29236
                     /locus_tag="VUR04_000715"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET5340649.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            29238..30296
                     /locus_tag="VUR04_000716"
     CDS             29238..30296
                     /locus_tag="VUR04_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET5340650.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARMSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            30306..31526
                     /gene="divIB"
                     /locus_tag="VUR04_000717"
     CDS             30306..31526
                     /gene="divIB"
                     /locus_tag="VUR04_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET5340651.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            31759..32460
                     /gene="pyrF"
                     /locus_tag="VUR04_000718"
     CDS             31759..32460
                     /gene="pyrF"
                     /locus_tag="VUR04_000718"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET5340652.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTSVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            32494..33126
                     /locus_tag="VUR04_000719"
     CDS             32494..33126
                     /locus_tag="VUR04_000719"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET5340653.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            33306..33709
                     /locus_tag="VUR04_000720"
                     /pseudo
     CDS             33306..33709
                     /locus_tag="VUR04_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33805..34569
                     /locus_tag="VUR04_000721"
     CDS             33805..34569
                     /locus_tag="VUR04_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340654.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGAYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVTYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            34569..35321
                     /locus_tag="VUR04_000722"
     CDS             34569..35321
                     /locus_tag="VUR04_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340655.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            35331..36029
                     /locus_tag="VUR04_000723"
     CDS             35331..36029
                     /locus_tag="VUR04_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340656.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLELWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            36026..36673
                     /locus_tag="VUR04_000724"
     CDS             36026..36673
                     /locus_tag="VUR04_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340657.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(36753..37618)
                     /locus_tag="VUR04_000725"
                     /pseudo
     CDS             complement(36753..37618)
                     /locus_tag="VUR04_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(37630..38387)
                     /locus_tag="VUR04_000726"
                     /pseudo
     CDS             complement(37630..38387)
                     /locus_tag="VUR04_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(38388..39065)
                     /locus_tag="VUR04_000727"
     CDS             complement(38388..39065)
                     /locus_tag="VUR04_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5340658.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLCVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(39025..39705)
                     /locus_tag="VUR04_000728"
     CDS             complement(39025..39705)
                     /locus_tag="VUR04_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5340659.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            39920..40066
                     /locus_tag="VUR04_000729"
     CDS             39920..40066
                     /locus_tag="VUR04_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET5340660.1"
                     /translation="MSYKTSNAEGHVDFINTYDLETMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            40194..41684
                     /gene="lysS"
                     /locus_tag="VUR04_000730"
     CDS             40194..41684
                     /gene="lysS"
                     /locus_tag="VUR04_000730"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET5340661.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            42308..43444
                     /gene="lctO"
                     /locus_tag="VUR04_000731"
     CDS             42308..43444
                     /gene="lctO"
                     /locus_tag="VUR04_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET5340662.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      43698..43786
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            44001..44669
                     /locus_tag="VUR04_000732"
     CDS             44001..44669
                     /locus_tag="VUR04_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET5340663.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            44912..45694
                     /gene="thiM"
                     /locus_tag="VUR04_000733"
     CDS             44912..45694
                     /gene="thiM"
                     /locus_tag="VUR04_000733"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET5340664.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            45696..46325
                     /locus_tag="VUR04_000734"
     CDS             45696..46325
                     /locus_tag="VUR04_000734"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET5340665.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      46534..46622
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            46883..47443
                     /locus_tag="VUR04_000735"
     CDS             46883..47443
                     /locus_tag="VUR04_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5340666.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNIFSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            47444..48829
                     /locus_tag="VUR04_000736"
     CDS             47444..48829
                     /locus_tag="VUR04_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340667.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKATLAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTSIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKIFQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            48831..49481
                     /locus_tag="VUR04_000737"
     CDS             48831..49481
                     /locus_tag="VUR04_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET5340668.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            49492..50184
                     /gene="tenA"
                     /locus_tag="VUR04_000738"
     CDS             49492..50184
                     /gene="tenA"
                     /locus_tag="VUR04_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET5340669.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            50189..50713
                     /gene="thiW"
                     /locus_tag="VUR04_000739"
     CDS             50189..50713
                     /gene="thiW"
                     /locus_tag="VUR04_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET5340670.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFHYSALGE
                     ILGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            50713..51516
                     /locus_tag="VUR04_000740"
     CDS             50713..51516
                     /locus_tag="VUR04_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET5340671.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            51509..52141
                     /locus_tag="VUR04_000741"
     CDS             51509..52141
                     /locus_tag="VUR04_000741"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET5340672.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(52351..53142)
                     /gene="thiD"
                     /locus_tag="VUR04_000742"
     CDS             complement(52351..53142)
                     /gene="thiD"
                     /locus_tag="VUR04_000742"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET5340673.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(53226..53324)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            53508..53903
                     /locus_tag="VUR04_000743"
     CDS             53508..53903
                     /locus_tag="VUR04_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET5340674.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            53914..54285
                     /locus_tag="VUR04_000744"
     CDS             53914..54285
                     /locus_tag="VUR04_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET5340675.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            54295..56538
                     /locus_tag="VUR04_000745"
     CDS             54295..56538
                     /locus_tag="VUR04_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET5340676.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEKK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVHPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            56745..58520
                     /gene="spxB"
                     /locus_tag="VUR04_000746"
     CDS             56745..58520
                     /gene="spxB"
                     /locus_tag="VUR04_000746"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET5340677.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            58631..58978
                     /locus_tag="VUR04_000747"
     CDS             58631..58978
                     /locus_tag="VUR04_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5340678.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(59095..59339)
                     /locus_tag="VUR04_000748"
                     /pseudo
     CDS             complement(59095..59339)
                     /locus_tag="VUR04_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            59507..59788
                     /locus_tag="VUR04_000749"
     CDS             59507..59788
                     /locus_tag="VUR04_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET5340679.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            59920..60864
                     /gene="manA"
                     /locus_tag="VUR04_000750"
     CDS             59920..60864
                     /gene="manA"
                     /locus_tag="VUR04_000750"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET5340680.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(60904..61821)
                     /locus_tag="VUR04_000751"
                     /pseudo
     CDS             complement(60904..61821)
                     /locus_tag="VUR04_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
BASE COUNT        18903 a        11214 c        13595 g        18222 t
ORIGIN      
        1 tacaacctca aagcggtact ttgagaaacc tgtggctatc ttcctagttt actttttgat
       61 ttttattgag tataagaggt ctttcctaag cagttagagg agaattttgc tatactgata
      121 ctagtaagtg gtaaaggagc agagcatgac ctacacaatc ttaatcgtag aagatgaata
      181 tctggtaaga caaggtttga ctaaactggt caatgtagca gcctacgata tggaaatcat
      241 cggtcaggct gaaaatggaa ggcaggcttg ggaattgatc caaaagcagg tgccagatat
      301 cattttaacc gatatcaaca tgcctcatct aaatggcatc cagttggcca gtttggtacg
      361 agaaacctat cctcaggttc atttggtctt tttaacaggt tacgatgatt ttgattatgc
      421 cttgtctgct gtcaaactag gtgtggacga ctacctgctc aaaccctttt ctcgtcagga
      481 tattgaggaa atgttgggga aaatcaaaca gaaactagac aaggaagaga aagaagagca
      541 gttacaagat ttattgacta ataggtttga aggaaacatg gcccagaaaa tccagtctca
      601 tctggctgat agccaattta gtttaaagtc tttagccagt gacttaggtt ttagtccgac
      661 ctatctgagt tctttgatta agaaagagtt gggcttgcct tttcaggatt atctggtgag
      721 agaacgtgtt aaacaagcca agctcttgct tttaactaca gatctgaaga tttatgagat
      781 cgcagagaag gttggttttg aagatatgaa ctattttacc caacgtttta agcagattgc
      841 aggtgtgaca cctcgtcagt ttaagaaggg agaagaccga tgaagcgttc ttctctttta
      901 gttagaatgg ttatttccat ctttctggtc tttctcattc tcctagctct ggttggaact
      961 ttctactatc aatcaagttc ttcagccatt gaggccacca ttgagggcaa cagccaaacg
     1021 accatcagcc agactagcca ctttattcag tcttatatca aaaaactaga aaccacttcg
     1081 accggtttga cccagcagac ggatgttctg gcctatgctg agaatcccag tcaagacaag
     1141 gtcgagggaa tccgagattt gtttttgacc atcttgaagt cagataagga cttgaaaact
     1201 gttgtgctgg tgaccaaatc tggtcaggtc atttctacag atgacagtgt gcagatgaaa
     1261 acttcctctg atatgatggc tgaggattgg taccaaaagg ccattcatca gggagctatg
     1321 cctgttttga ctccagctcg taaatcagat agtcagtggg tcatttctgt cactcaagaa
     1381 cttgttgatg caaagggagc caatcttggt gtgcttcgtt tggatatttc ttatgaaact
     1441 ctggaagcct atctcaatca actccagttg gggcagcagg gctttgcctt cattatcaat
     1501 gaaaaccatg aatttgtcta ccatcctcaa cacacagttt atagttcgtc tagcaaaatg
     1561 gaggctatga aaccctacat cgatacaggt cagggttata ctcctggtca caaatcctac
     1621 gtcagtcaag agaagattgc aggaactgat tggacggtac ttggcgtgtc atcattggaa
     1681 aagttagacc aggttcggag tcagctcttg tggaccttgc ttggggccag tgtcacatct
     1741 cttcttgtct gtctctgctt agtgtggttc agtcttaaac gctggattgc tcctttgaag
     1801 gatttgagag aaaccatgtt ggaaattgct tctggtgctc aaaatcttcg tgccaaggaa
     1861 gttggtgcct atgaactgag agaagtaact cgccaattta atgccatgtt ggatcagatt
     1921 gatcagttga tggtagctat tcgtagccag gaagaaacga cccgtcagta ccaacttcaa
     1981 gccctttcga gccagattaa tccacatttc ctctataaca ctttggacac catcatctgg
     2041 atggctgaat ttcatgatag tcagcgagtg gtgcaggtga ccaagtcctt ggcaacctat
     2101 ttccgcttgg cgctcaatca aggcaaggac ttgatttgtc tctctgacga aatcaatcat
     2161 gtccgccagt atctctttat ccagaaacaa cgctatggag ataagctgga atatgaaatt
     2221 aatgaaaatg ttgcctttga taatttagtc ttacccaagc tggtcctaca accccttgta
     2281 gaaaatgctc tttaccatgg cattaaggaa aaggaaggtc agggccatat taaactttct
     2341 gtccagaaac aggattcggg attggtcatc cgtattgagg atgatggcgt tggcttccaa
     2401 gatgctggtg atagtagtca aagtcaactc aaacgtgggg gagttggtct tcaaaatgtc
     2461 gatcaacggc tcaaacttca ttttggagcc aattaccaga tgaagattga ttctagaccc
     2521 caaaaaggga cgaaagttga aatatatata aatagaatag aaactagcta actcccagtc
     2581 aattctggga gttttatgcg taattgggca aactttctag gttgtctatc ttgctaaaaa
     2641 caagaaaaaa cggtatgata gaagagtaac aacagaggta acagagatga acgagacaca
     2701 gattcaaaga gaaacacgtc aggtagtgga agatgtttta gaaaagacca atttgaagca
     2761 gggggccctt tttgttttag gtctatcttc tagtgaggtg ctaggtggtc agattgggaa
     2821 agaatccagt caagagattg gtgagctgat agtggagact atcttgggta ttctaggtag
     2881 tagaggtatc catttagcag ttcaaggttg tgagcatgtc aatcgggctc tcgttgttga
     2941 acgtcaggtg gcagagcagt ttgatctgga aattgtcagt gtccatccta ctcttcatgc
     3001 aggaggttcg gggcagttgg cagcctttaa gtttatgcag gatccagttg aggttgaatt
     3061 tatcaaggct catgctggat tggatatcgg agacactgca attggcatgc atgtcaagca
     3121 tgttcaggtt ccgattcgcc ctattttgag agagattggt catgcccatg taacggcact
     3181 ggctaatcgt ccaaaattaa tcggaggtgc gcgtgcgcac tatccgcaag atgctattag
     3241 aaagtcctga gaatgaataa aggagataaa agtgtttaaa aaagaccgtt tttcaattcg
     3301 taagattaag ggagttgtag gctctgtatt tcttggaagc cttttgatgg ctccttctgt
     3361 agtggacgca gccacctatc actatgtaaa taaagagatt atttcacaag aagctaaaga
     3421 tttaattcag acaggaaagc ctgacaggaa tgaagttgta tatggtttgg tgtatcaaaa
     3481 agatcagttg cctcaaacag ggacagaagc atctgttttg acagcttttg gtttgctgac
     3541 tgttgggagc ttgtttttaa tctacaagag aaagaaaatt gctagcgtct ttctagttgg
     3601 agctatggga ttggtagttc ttcctagtgc aggggctgta gacccagttg cgaccctagc
     3661 gctggctagt cgagagggtg ttgttgaaat ggagggctat cgctatgttg gttatctatc
     3721 aggtgacatc ctcaaaacgc ttggcttgga cactgtttta gaagaaacct cagcaaaacc
     3781 tggagaggtg actgtagtcg aagttgagac tcctcaatca acaacaaatc aggagcaagc
     3841 taggacagaa aaccaagtag tagagacaga ggaagctcca aaagaagaag cacctagaac
     3901 agaagaaagt ccaaaggaag aaccaaaatc ggaggtaaaa cctactgacg acacccttcc
     3961 taaagtagaa gaggggaaag aagattcagc agaaccagct ccagttgaag aagtaggtgg
     4021 agaagttgag tcaaaaccag aggaaaaagt agcagttaag ccagaaaagc aaccagaagc
     4081 tcctgaagaa gagaaggctg tagaggaaac accgaaacaa gaagagtcaa ctccagatac
     4141 caaggctgaa gaaactgtag aaccaaaaga ggagactgtt aatcaacctg ttgaacaacc
     4201 aaaagtggaa acgcctgctg tagaaaaaca aacggaacca acagaggaac caaaagtaga
     4261 acaagtaggt gaaccagtcg agccaagtga agacgaaaag gcaccagtct ctccagaaaa
     4321 gcaaccagaa gctcctgaag aagagaaggc tgtagaggaa acaccgaaac cagaagataa
     4381 aataaagggt attggtacta aagaaccagt tgataaaagt gagttaaata atcaaattga
     4441 taaagctagt tcagtttctc ctactgatta ttctacagca agttacaatg ctcttggacc
     4501 tgttttagaa actgcaaaag gtgtctatgc ttcagagcct gtaaaacagc ctgaggtaaa
     4561 tagcgagaca aataaactta aaacggctat tgacgctcta aacgttgata aaagtgaatt
     4621 acaggaacaa ttaagagttg ctgaacaaaa acaacaagct gactatagcg ctaaaacttg
     4681 gagggaattc aaaattgctg aacttcaagc taaagaaatc aacaaccaaa ctacaccact
     4741 tcctaaacaa agtgaaatag atgcagctac taaggctctt caagacgctc ttcaagctct
     4801 tgctatagat aaaactgtat tacaaaacgc tattaacaca gctaatagca aacgtgaaga
     4861 agagtatact gctcagacat ggaaagcgtt agaagatgct cttacagcag tgaatcctgt
     4921 taatgaagat gaaactgcaa ctcaaagcaa agtagacgaa gctactagaa acttagaaga
     4981 agctatcaat aacctagttc tattaactga aaaaccggta ttaacattta ttgagactga
     5041 taagaaagca ttagaacgtg aagtagttgc taagtattct ctagaaaacc aaaataaaac
     5101 aaaaattaaa tcaatcacag ctactctgaa aaaaggagaa acagttgtta gcactgtaga
     5161 gcttataggc gatgatgtaa ctaatgaaac tataagctct gcatttaaga atctagagta
     5221 ctacaaagaa tacaccctat ctacaactat ggtttacgat agaggtgacg gtgatgtaac
     5281 agaaatctta gataatcaac caatccaact agatcttaaa aaagttgagc ttaaaaatat
     5341 taaacgtaca gatttaatca aatacgaaaa tggaaaagaa actaatgaat cactaataac
     5401 aactgttcct gatgataagc ggaattatta tttaaaaata acttcaaaga atcaaaaaac
     5461 tacattacta gctgttaaaa atatagaaga aactacggtt aacggaacac ctgtatataa
     5521 agttacagca atcgcagaca atttagtctc tagaactgct gataataaat ttgaagaaga
     5581 atacgttcac tatattgaaa aacctaaagt ccacgaagat aatgtatatt ataacttcaa
     5641 agaattagtg gaggctattc aaaacgatcc ttcaaaagaa tatcgtctgg gacaatcaat
     5701 gagcgctaga aatgttgttc ctaatggaaa atcatatatc actaaagaat ttacaggaaa
     5761 acttttaagt tctgaaggaa aacaatttgc tatcactgag ttggaacatc cattatttaa
     5821 tgtgataaca aacgcaacga taaataatgt gaattttgaa aatgtagaga tagaacgttc
     5881 tggtcaagat aatattgcat cattagccaa tactatgaaa ggttcttcag ttattacaaa
     5941 tgtcaaaatt acaggcacac tttcaggtcg taataatgtt gctggatttg taaataatat
     6001 gaatgatgga actcgtattg aaaatgttgc tttctttggc aaactacact ctacaagtgg
     6061 aaatggctct catacagggg gaattgcagg tacaaactat agaggaattg ttagaaaagc
     6121 atatgttgat gctactatta caggaaacaa aacacgcgcc agcttgttag ttcctaaagt
     6181 agattatgga ttaactctag accatcttat tggtacaaaa gctctcctaa ctgagtcggt
     6241 tgtaaaaggt aaaatagatg tttcaaatcc agtagaagtt ggagcaatag caagtaagac
     6301 ttggcctgta ggtacggtaa gtaattctgt cagctatgct aagattatcc gtggagagga
     6361 gttattcggc tctaacgacg ttgatgattc tgattatgct agtgctcata taaaagattt
     6421 atatgcggta gagggatatt cgtcaggtaa tagatcattt aggaaatcta aaacatttac
     6481 taaattaact aaagaacaag ctgatgctaa agttactact ttcaatatta ctgctgataa
     6541 attagaaagt gatctatctc ctcttgcaaa acttaatgaa gaaaaagcct attctagtat
     6601 tcaagattat aacgctgaat ataaccaagc ctataaaaat cttgaaaaat taataccatt
     6661 ctacaataaa gattatattg tatatcaagg taataaatta aataaagaac accatctaaa
     6721 tactaaagaa gttctttctg ttaccgcgat gaacaacaat gagtttatca caaacctaga
     6781 tgaagctaat aaaattattg ttcactatgc ggacggtaca aaagattact ttaacttgtc
     6841 ttctagcagt gaaggtttaa gtaatgtaaa agaatatact ataactgact taggaattaa
     6901 atatacacct aatatcgttc aaaaagataa cactactctt gttaatgata taaaatctat
     6961 tttagaatca gtagagcttc agtctcaaac gatgtatcag catctaaatc gattaggtga
     7021 ctatagagtt aatgcaatca aagatttata tttagaagaa agcttcacag atgttaaaga
     7081 aaacttaaca aacctaatca caaaattagt tcaaaacgaa gaacatcaac taaatgattc
     7141 tccagctgct cgtcaaatga ttcgtgataa agtcgagaaa aacaaagcag ctttattact
     7201 aggtttaact tacctaaatc gttactatgg agttaaattt ggtgatgtta atattaaaga
     7261 attaatgcta ttcaaaccag atttctatgg tgaaaaagtt agcgtattag acagattaat
     7321 tgaaatcggt tctaaagaga acaacattaa aggttcacgt acattcgacg cattcggtca
     7381 agtattggct aaatatacta aatcaggtaa tttagatgca tttttaaatt ataatagaca
     7441 attgttcaca aatatagaca atatgaacga ttggtttatt gatgctacag aagaccatgt
     7501 ctacatcgca gaacgcgctt ctgaggtcga agaaattaaa aattctaaac atcgtgcatt
     7561 cgataattta aaacgaagtc accttagaaa tactatactc ccactactga atattgataa
     7621 agcacatctt tatttaattt caaattataa tgcaattgcc tttggtagtg cagagcgatt
     7681 aggtaaaaaa tcattagaag atattaaaga tatcgttaac aaagctgcag atggttatag
     7741 aaactattat gatttctggt atcgtctagc gtctgataac gttaaacaac gactactaag
     7801 agatgctgtt attcctattt gggaaggtta taacgctcct ggtggatggg ttgaaaaata
     7861 tggccgctat aataccgaca aagtatatac tcctcttaga gaattctttg gtcctatgga
     7921 taagtattat aattataatg gaacaggagc ttatgctgct atatatccta actctgatga
     7981 tattagaact gatgtaaaat atgttcattt agaaatggtt ggtgaatacg gtatttcagt
     8041 ttacacacat gaaacaacac acgtcaacga ccgtgcgatt tacttaggtg gctttggaca
     8101 ccgtgaaggt actgatgctg aagcatatgc tcagggtatg ctacaaactc ctgttactgg
     8161 tagtggattt gatgagtttg gttctttagg tattaatatg gtatttaaac gcaaaaatga
     8221 tgggaatcag tggtatatta cagatccaaa aactctaaaa acacgagaag atattaatag
     8281 atatatgagg ggttataatg acactttaac tcttcttgat gaaattgagg ctgaatctgt
     8341 gatttctcaa caaaataaag atttaaatag tgcatggttc aaaaaaatag atagagaata
     8401 ccgtgataac aataaattaa atcaatggga taaaattcga aatctaagtc aagaagagaa
     8461 aaatgaatta aatattcaat ctgttaatga tttagttgat caacaattaa tgactaatcg
     8521 caatccaggt aatggtatct ataaacccga agcaattagc tataacgatc aatcacctta
     8581 tgtaggtgtt agaatgatga ccggtatcta cggaggtaat actagtaaag gtgctcctgg
     8641 agctgtttca ttcaaacata atgcttttag attatggggt tactacggat acgaaaatgg
     8701 gttcttaggt tatgcttcaa ataaatataa acaacaatct aaaacagatg gtgagtctgt
     8761 tctaagtgat gaatatatta tcaagaaaat atctaacaat acatttaata ctattgaaga
     8821 atttaaaaaa gcttacttca aagaagttaa agataaagca acgaaaggat taacaacatt
     8881 cgaagtaaat ggttcttccg tttcatcata cgatgattta ctgacattgt ttaaagaagc
     8941 tgttaaaaaa gatgccgaaa ctcttaaaca agaagcaaac ggtaataaaa cagtatctat
     9001 gaataataca gttaaattaa aagaaaaagt ttataagaaa cttcttcaac aaacaaatag
     9061 ctttaaaact tcaatcttta aataattgaa atctctcgtc tgctttgcgg atgagggttt
     9121 tcttatttta tgctatactt aaggtatgca tagaaaaaca gtgattgatt ttaggacttt
     9181 gggggagaga tataccttta ccaagcctat tagagagtta aaaacgagag atttagcaga
     9241 agtggctgac ttgctggcac aagtggaaaa ctatcaaacg cagggctact atgtggtggg
     9301 gtatgtcagc tacgaggctg cacctgcttt tgaggagaaa ttagcagttc acaaggttcc
     9361 tctactgggc gagtacttgc tttactttac tgttcacgat agggtggaga cctcccctat
     9421 tcctctgact tatgaggata ttgatttgcc ctcaaattgg caggaagtaa cgtctgcaga
     9481 ggactatgaa aaggccattg cccagataca ccatcacttg aggcagggag acacctatca
     9541 ggtcaactac accgtccaac tcaagcaaaa gttaagtgcc aatccttttg ccatctacaa
     9601 tcgtatggtg gtagagcagg aggcgggcta caatgcctat gtggaacatg acgagatggc
     9661 agtgatttcc atgagcccag agctcttttt tgagcaaaat gatcgcgagt tgacaacacg
     9721 accaatgaag gggacgactc agcgtggggt aactgaccaa gaagatcttg aacaggccag
     9781 ttggttggga caggatccca aaaatcgctc tgaaaatatg atgattgtgg acctcttgcg
     9841 caatgatatg aaccgtattt ctgaagttgg gagcgagcac gtggagcgtc tgtgtcaggt
     9901 agagcagtat tcaactgttt ggcagatgac ttcgaccatc aagagtcagt tgcgagagga
     9961 tgtggacctt gttgaaatct tccgctcact ctttccttgt ggttccataa cgggtgcacc
    10021 gaaaattgcg acaatggaga ttatcaagga cttggagcct caaccgcgtg gagtctactg
    10081 tggaacgatt ggtctcttgc ttccaaatgg acgacggatt tttaatgtgg ccattcgtac
    10141 cattcaactt cacaaaggtc aagcaattta tggagttggc ggagggatta cttgggatag
    10201 cacatgggaa tctgaatacc gagaggttca tcaaaaggca gcagttcttt atcgtaaaca
    10261 agctcgcttc caactgatta cgacagggga aatcagccag aagaacctgc tgtttgaaga
    10321 tcaacatctg gaaagactga gaaaagccag tcgttatttt gcctttcctt ttgatgcaga
    10381 agacttggga cacaagattg aggaagagtg tcaggattgt gaagctaatc aagattaccg
    10441 cttgcgaatc agccttagca aatctggaga gatagaagtc aatcgtcaag tattaacccc
    10501 tctcagtaca agcttttgtc aggcccaagt ctgtcttcag gaagctgctt tgaatcaatc
    10561 ctttacctac tttaaaacca ctcaccgacc gcatttgagc ctaggagaac aagagaagat
    10621 ttaccacaat aagtcaggag aactgcttga aacctctata ggaaatttgg ttctgaaaat
    10681 cgctggaaaa ctctacacac cgcctatccg acttggaatc ttgccaggaa tttaccgtca
    10741 gcatttgcta gaaataggac aggtagaaga gaaagtcttg accttggcag atttaaccca
    10801 agcagaagct atttacggct gtaatgcagt gagaggcttg tatgaactaa gccttgagga
    10861 gaactagatg aaattgatat ttttgcatgg gttagggcag tcagcagagt cttggaaaga
    10921 agttcggaat ctactgacag attatccttc tgaggctatc gagttatttc cttctggagt
    10981 tagtaactat caacaagcta aagagcgagt ttatcagcac ctagctcaag agacagaacc
    11041 ttttgttttg attggattgt ccttaggtgc tgccctgaca ctagaacttt ccagttacga
    11101 tttaccaaat cttcgagctt tgattctgtc aggatgcccg cttaaattag cagggaatat
    11161 cctattttat cttcaattgc tgatttttaa actacttccc aaaagagtat ttgaaaaaca
    11221 gggagcagac aagactctta tggtcggagt ttctgaggaa ttgaagacac ttgatttaac
    11281 ggatatagca gggacttgct cctatccaac cttactaatt tgtggcagca aagataaacc
    11341 gaatcttagt tctatgaaag ctctccatag actgttaaca gattcgcagt ttcagatcat
    11401 tcctgatggc cctcatgtct tgaataaggc aaaaccaaag gagtttgtag aaaagaccag
    11461 aagtttcctt gaattgctga aataagtttg ataaaataat attgaaatcg atatcataat
    11521 tatgggagaa agaaatgaat aaacgtctat ttttaaaaat gagtctggtg acgttgccaa
    11581 ttttagcctt gttttcacaa ccagttttgg cggaagaaaa catccatttt tcgagctgta
    11641 aggaagcttg ggcgaatggc tattcggata ttcacgaggg ggaacctggt tattctgcca
    11701 agttagaccg tgatcatgat ggtgtggctt gcgaattgaa aaatgctcct aagggtgctt
    11761 ttaaagcaaa acagtcaacg gctattcaaa tcaacacaag ttcagcaaca acaagtggtt
    11821 gggttaagca ggacggcgct tggtactact ttgatggaaa tggaaatcta gtgaaaaatg
    11881 catggcaggg aagctattac ctgaaagctg atggtaaaat ggcacagagt gaatggattt
    11941 atgactcttc ttatcaagct tggtattatt tgaaatcaga tggttcttat gcaaaaaatg
    12001 catggcaagg agcttattac cttaaatcaa acggtaaaat ggtacaaggt gagtggattt
    12061 atgattcttc ttaccaagca tggtattact tgaaatcaga tggttcatat gctcgcaatg
    12121 catggcaagg aaactactat ttgaaatcag atggtaaaat ggctaaaggt gaatgggttt
    12181 atgatgccac ctatcaagct tggtattatt tgacatcaga tggttcttat gcttacagta
    12241 catggcaagg aaattactat ctaaaatcgg atggtaaaat ggctgtcaat gaatgggttg
    12301 atggtggacg ttattatgtt ggcgctgacg gagtttggaa ggaaggtcaa gcaagtacag
    12361 cttcttctag taatgatagc aatagtgaat attctgctgc tttaggaaag gcaaaaagtt
    12421 ataattcgtt attccacatg tcaaaaaaaa cgtatgtata gacaattaac ttctgatttt
    12481 gataaatttt caaatgatgc agctcaatat gccattgatc attagatgat taacagatac
    12541 tggtaggcga aaaaattcct tataattcat ttacgcaaac ctttgcataa gtgaatggat
    12601 tttgatatac tagtactgta agcattttca attactacac aatgaaaaag gagaatatga
    12661 tgagtcaaaa gattattggg attgaccttg gtggaacttc tatcaaattt gcaatcttaa
    12721 caacagcagg agaaatccaa ggaaaatggt caatcaagac caacattttg gatgagggaa
    12781 gtcatatcgt tgatgatatg attgagtcta ttcaacatcg tttggacttg cttggattgg
    12841 cagcagcgga cttccaaggc attggaatgg gatcaccagg tgtggttgac cgtgacaaag
    12901 ggactgttat cggtgcctac aacttgaact ggaaaaccct tcaaccaatc aaacaaaaga
    12961 ttgaaaaagc tttgggcatt ccatttttca tcgataatga tgccaacgta gcagctcttg
    13021 gtgagcgctg gatgggtgct ggagataacc aaccagacgt tgtctttatg acactcggta
    13081 ctggtgttgg tggcggtatc gtcgcagaag gcaaattgct tcacggtgtt gctggtgcag
    13141 caggtgagct tggtcacatc actgttgact ttgaccagcc aatctcatgt acttgcggta
    13201 agaaaggctg ccttgagaca gttgcttcag caacagggat tgtcaacttg actcgtcgct
    13261 atgccgatga atacgaaggc gatgcagcct tgaaacgctt gattgataat ggagaagaag
    13321 taactgctaa gactgtcttt gatctcgcaa aagaaggaga cgaccttgct ttgattgttt
    13381 accgtaactt ctcacgttac ttgggaatcg cttgtgctaa cattggttca atcctaaacc
    13441 catcaacaat cgtcatcggt ggtggtgtgt cagctgcggg agaattcctt ctacaaggtg
    13501 ttcaaaaagt ttacgatgaa aatagtttcc cacaagtacg cacatctact aaattagctc
    13561 ttgcaactct aggaaatgac gctggagtta tcggagcagc atcacttgta ttgcaataag
    13621 ataatgagag aggaaaatgc taacctagag ttagtaatgt tcctctttta ttttttatgc
    13681 tatactagtt aggacaatga atgaggtgag agtaaatgac aaaagcagat acgattttta
    13741 aagagaatat tgaatgcatt ctaaaggaag gtgttttctc agagcaagct cgtcctaagt
    13801 acaaggatgg gactgttgct aattccaagt atgtaactgg tgccttttcc gagtacgact
    13861 tatctaaagg agaatttcct atcacaacct tgcgtcccat tgcaatcaaa tccgccatca
    13921 aagaagttct ctggatttac caagaccagt caaatagctt agaagtgctt aatgacaagt
    13981 acaatgttca ctactggaat gactgggaag ttggagacac gggaaccatt ggtgagcgct
    14041 atggtgccgt tgttaagaaa cacgacatta tcaataagct tctcaaacag ttggaaacca
    14101 atccttggaa tcgccgcaat attatttcgc tctgggatta ccaagctttc gaagaaacag
    14161 atgggctgct cccgtgcgcc tttcagacca tgtttgatgt ccggcgtgtt gatggggaaa
    14221 tctatctgga tgcgaccttg acccagcgct ccaatgatat gctggtggcc caccacatca
    14281 acgctatgca gtatgtggct ttacagatga tgattgccaa acattttggt tggaaggttg
    14341 ggaagttctt ctatttcatc aacaacctcc atatctatga taatcaattt gaacaagctc
    14401 aggaattgct ccgtcgggag ccgtcaaact gccaaccacg cttggtttta aatgttcctg
    14461 atgggactaa tttctttgat atcaaagcag aagattttga gttggtggat tatgaccctg
    14521 ttaagccaca gttgaagttt gacctagcta tttaaaagaa tagaaaaaag aagttgagaa
    14581 taatcccaac ttcttttgtt tcttaacgtg atacgcggcg acgagctgct tttttacgat
    14641 tttcttcgat gaaagctgct ttttgctctt ctggttcgat tactttcttt ttaaatgcgt
    14701 atactgcacc tgcaacggca gcgacagttc ctgcgacacc tgttacaaga cctttagcga
    14761 atcctttagc catgagtctt cctcctttat attctcaatc agccagcctc ctcaagaggt
    14821 cacatttttc tgactgacct ttttgtgtta taataatagt aacgaaaaaa tgggaatttt
    14881 tcaaggaaaa aagatgaaaa caaaaataat tgtgattgtt ggaccgactg ctgttggaaa
    14941 gacggctcta gctattgaag ttgcaaagcg ctttaatggc gaagtggtta gtggagatag
    15001 ccagcaagtc tatcgaggac ttgatattgg gacggccaag gctagtccag aagagcaggc
    15061 agctgttcct catcatttaa tcgatgttag agagataacc gagtcttact cggcttttga
    15121 ttttgtttca gaagctaaga tgactattga ggatattcag agccgtggca agctagccat
    15181 tatcgccggt gggactggac tttatatcca gagcttgcta gaaggttacc acctaggtgg
    15241 ggagactcct catgaggaga ttttagctta tcgagctagt ttggagccat attcagatga
    15301 ggaattagcc catttggtgg agcaagcagg ccttgagatt ccccagttta atcgtcgtcg
    15361 tgctatgcgt gccttagaaa ttgcccattt tggtcaggat ttggaaaatc aagagatctt
    15421 gtatgaaccg ctgattatct gcttggatga tgaacgtagt caactttatg agcgtatcaa
    15481 ccaccgagtg gatttgatgt ttgaggctgg gcttttggat gaggccaagt ggctgtttga
    15541 ccattcccct aatgtacagg ctgctaaagg aattggctat aaggaactct ttccttattt
    15601 ccgtggagag cagacctttg aggaagctcg tgagagtctt aaacaggcga cccgtcgttt
    15661 tgccaagcgt cagctgacct ggttccgtaa tcgcatgcag gtcacctttt atcagattgg
    15721 agaatctggt gtacaagacc gcattttaag ccagatagag gagtttttag atgattgaaa
    15781 cggagaaaaa agaggagcga gtcctgctga ttggtgtgga attgcagggt atggacagtt
    15841 ttgacctctc catggaagaa ttggctagtt tagcgaaaac ggcaggggca gtcgttgtag
    15901 atagctacag acaaaaacgt gaaaaatatg attccaagac cttcgtcggc tctggtaagt
    15961 tggaagagat tgcgcttatg gtggatgcag aagaaatcac tactgtcatc gtcaacaacc
    16021 gtctgacccc aaggcagaat gtcaatctag aggaagttct cggtgttaag gtcattgacc
    16081 gtatgcagtt gattttggat atctttgcca tgcgggctcg aagccatgaa gggaagctcc
    16141 aagtccacct agcccaactc aaatacctct tgcctcgctt ggttggtcag gggattatgc
    16201 tcagccgtca ggcaggggga attggttccc gtggtcctgg tgaaagccag ctggagctga
    16261 accgtcgtag cgttcgcaat caaatcacgg atatcgagcg ccagctcaag gtggttgaga
    16321 aaaatcgggc gactgtcaga gaaaaacgtt tggagtctag cacctttaag attggtttga
    16381 ttggttatac caatgctggg aaatcaacta tcatgaacat cttgaccagt aagacccagt
    16441 atgaagcaga tgagctcttt gcgactctgg atgcgacaac caagagtatt catctgggag
    16501 gcaatctcca agtaactttg acagataccg ttggctttat tcaagatttg ccgacagagt
    16561 tggtgtccag tttcaagtca accttggaag aaagcaagca tgtggacctt ctggttcatg
    16621 ttatcgatgc tagcaatcct taccacgagg agcatgaaaa aacggttctc tccatcatga
    16681 aagacctgga catggaagat attcctcact tgacgcttta taataaagcg gatttggtgg
    16741 aggatttcac gcctacccaa acgccatata ccctcatttc tgccaagtct gaggacagtc
    16801 gtgaaaactt gcaagcatta ttgctagata agattaagga aatttttgaa gcatttaccc
    16861 tgcgagtgcc tttttcaaag tcctacaaga ttcatgattt agagagtgtt gcaattctgg
    16921 aagaacgtga ttatcaggaa gacggcgaag tgattacagg ctacatttcc gagaaaaata
    16981 aatggaggtt agaagaattt tatgactgat attaaaactt tggctctaaa gtatggaggt
    17041 tatacaagtc tggacaaggt ctatctggat cagcttctag ctggtaaaac agagcaggag
    17101 cagttaacac ttattacacc tccgccaagt gttgttaatg cctactttgc agaactctat
    17161 cagaaaaaaa gtcctcaggc tgcgacggat tattttgcag aactcagtca ggaactgaat
    17221 ctttacaata ctgagccaag tttcacccta gaaaataagc cttttattcg gcttaatctg
    17281 tctggtaaat cctttggttt ttgttatgag agtgacggct ttggtcggat tttctctgaa
    17341 aatgaggaga aaatctcgga tgacttgctc tttgaaattg cgcaaatttt ctcccatcaa
    17401 ttagtctttg aagagtctgg taagatttac atgaagcctg tcaaggacga ggaagttgtc
    17461 agcctagaaa gtctcacagc tttgactgat ttggaaagat tggctgatgg tcgaaaacgt
    17521 ctcaaaggct acagccaaga ggatttattg caagaagctg ctgctttttc tggcaaacgc
    17581 tatttccgat cggaaaaccg cacagccatg ttatatattg attaattaga aagtatcgaa
    17641 tggatattca atttttagga acgggggctg gtcagccctc taaagcccgc aacgtttcaa
    17701 gtctcgccct gaaacttttg gacgagatta acgaagtttg gctctttgac tgtggagaag
    17761 gtacgcaaaa tcgcattctg gaaaccacaa ttcgaccacg taaggtcagc aaaatcttta
    17821 ttacccatct gcatggagac cacatttttg gtttgccagg tttcctttct agccgtgcct
    17881 ttcaggccaa tgaagagcag acagatttgg aaatctacgg acctcaagga atcaagtcat
    17941 ttgtcttaac cagccttcgt gtgtcaggtt ctcgtctgcc ctaccgcatt catttccatg
    18001 agtttgacca agattctctg ggtaaaattc ttgaaaccga taaattcact gtgtatgcag
    18061 aggagctgga ccacactatt ttctgtgttg gctatcgtgt catgcaaaag gatctagaag
    18121 ggacgctgga tgctgaaaaa ctcaaggctg ctggtgttcc gttcggcccg ctttttggta
    18181 aaatcaaaaa cggccaggat cttgttttgg aagacggaac tgaaatcaag gcagcagact
    18241 atatctcagc gccacgtcca ggtaagatta tcactatttt aggagacact cgaaaaacgg
    18301 atgccagtgt gcgtctggct gtcaatgcag atgtcctagt tcatgagtcc acttatggca
    18361 agggtgatga aaaaattgct cgtaaccatg gtcactcaac taatatgcaa gctgcacaag
    18421 tagcggtaga agcaggtgcc aaacgcctcc tactcaacca tatcagtgcc cgtttcctct
    18481 caaaagatat aagcaaactc aagaaggacg ctgccacaat ttttgaaaat gtccatgtgg
    18541 tcaaagactt ggaagaagtg gaaatctagc agtcacagaa aggataagta tgcctactat
    18601 tctcattacc ggagctagcg gtggtctagc tcaagaaatg gtcaaactct tgcccaatga
    18661 ccaactcatc ttgcttggta gaaataagga aaaattagcc caactctacg gaaattattc
    18721 ccatgcagaa ttgattgaaa ttgatattac cgacgattca gccctagaag ctctggtaac
    18781 tgatctttat ctccgctatg gcaagattga tgtcttgatt aacaacgctg gttacgggat
    18841 ttttgaggga tttgaccaga ttgctgataa agatattcac cagatgtttg aggtcaatac
    18901 ctttgccctg atgaatctgt ctcgtcacct tgcggctcgt atgaaggaaa gcagcaaagg
    18961 gcatatcatc aacatcgtca gcatggcagg tctaatagct actggcaagt ctagtcttta
    19021 ctcagcgacc aagtttgcgg ctattggttt ttcaaatgct ctgcgactcg aacttatgcc
    19081 ctatggagtc tatgtgacaa cagtcaatcc aggtccaatc cgaacaggat tttttgacca
    19141 agctgaccca gatggaactt atcttaaatc ggttgaccgc ttcctcttag aggcagatgc
    19201 agtggctaaa aagattgtca agattatagg caaaaataaa cgagaactca atctcccgat
    19261 tttgttgaac ctagcccata agttttatac tctctttccc aagctagctg ataagttggc
    19321 aggggaaact tttaattata agtaaaaaga accaatgtgc aggttgttgc tagcctacat
    19381 attggttctt atcatttctc aactatcaaa ctgaacttct tctagtagat agtcgataaa
    19441 gcgttcgccc atcttagata ggctggtttt ctcatgctgg atatagacca gctcaatcgg
    19501 gtcatcaata tccagtggga tagaaacgat attgtctccg tttaggttgc tgttcaaaat
    19561 ccctgtcgca atggtataac catccaaacc aatcaagaga ttaaagaggg tggcacggtc
    19621 actgaccaca atggatttct tgtggtgttc ctgagaaaga atctcttctg aaaagtagaa
    19681 ggagttgtgc gtcccttggt catagctgag gtaagggaaa ttctccaaat cagacagttt
    19741 caccttgtct ttctttgcca gagggttggt cttgctgaca aagatatgcg gttgcgctgt
    19801 gaagagatgg tgggctagca ggtgattgtc atccagcatc ttggttaaaa catcacggtt
    19861 gtaactgttt aagaagagga ccccgacctc actgcggaag ttcttgacgt cgtcgataat
    19921 ctcccaagtc cgagtttcac gaaggaagag ttcgtatttc tccatatcgc ttttcttgag
    19981 caaagagaca aaggcattga ccacaaaggc atagtgttga gacgaaacgc taaagagttc
    20041 gcggtgggcg acaggatttt tatagcgttc ctccagaagc tgggtctgct cgacaacctg
    20101 acgggcataa gagagaaact ccatcccatc acgggtcaag gtgattccct tgggattgcg
    20161 gataaagatc tcaatgccca tttcattttc caaatctcgc actgcattgg agagacttgg
    20221 ctgagtgata aagagttgct tggctgcctc attcatggag ccagtttcga cgattttgat
    20281 aatataatgt aattgttgaa ttctcatgtt tttattgtac catacttgcc ttagaatcgc
    20341 taaagaagat aggaaaataa ggagcattgt atgagtctct tcttgaaaaa aacacaaaat
    20401 tttgctagaa tgagtcttat gaaaacattc tatgatgtgc agcaattcct caaacgattt
    20461 ggtattattg tttacatggg aaaacgctta tatgatattg aactgatgaa gttggaacta
    20521 tctcggattt acgatgcagg gttgatggat aaattagact atctagaggc agaagcagtt
    20581 cttcgcagag agcacaaggt agaattggat tatattgaga aaaatggaga aaagaactaa
    20641 tggttacttg gattttgtgg gcacttatac tagcaatgtt ggcgtggatg ggctttaact
    20701 atcttcgtat tcgccgtgcg gctaaaattg tggacaataa ggagtttgaa gccttgattc
    20761 gtacgggtca attgattgat ttgcgcgacc cagcagaatt ccacagaaaa catatccttg
    20821 gtgcgcgcaa tattccttca agtcagttga aaactagtct tgcagcactt cgtaaagata
    20881 aacctgtcct tctctacgaa aaccaacgtg cgcaacgagt tacaaatgca gctctttact
    20941 tgaaaaaaca aggtttttct gagatttata tcctttctta tggcttggat tcttggaaag
    21001 ggaaagtgaa gactagctaa ccttatttcc aaattagtcg aatgatagga tgaagctatt
    21061 gttttatagt ataattaatt tgtataaaat ttaaagagtt cttagaacat gaaagaaaag
    21121 aagaaaaatc cactttttgt gggtatcttg tcgattattc ttggtttgtt atttccaatt
    21181 gtaggcctga ttttgggtat cataggattg gtcttggcta tttcatacca aaaagagtca
    21241 caattagact ataaaataga aaagattctt aatatcttag gaattgtgat ttctgtagtt
    21301 aactggattg tagtaatcgc cttaattttt cggtaaataa aagaaaaaag ctttagtttt
    21361 aaagcttttt ttattttatc gactcatctc taaatagttt ttaatgattt gtaactcttt
    21421 ttggttcaaa gggcggtagt taccttctgc taaatctggg ttcaatgtga agtccccaaa
    21481 ttggattctc ttgaggctag tcaccttaac accaaccgag aggaacattt tcttgatttg
    21541 atgaaatttt ccttctgaaa tggtgataga ggcttgactg agggagggac ttgctgatag
    21601 aatctctagt cttgcaggtt tacagatagt gccatctaaa aagacaattc ctttttgaaa
    21661 ggtttggata tggtcaggtg ttagaagtcc attaacctca acttgataag tcttatcgac
    21721 atgatattgg ggatggagga gttggaagcc caagggaccg ttatcggtca agagaaggag
    21781 tcctgttgta tctcggtcca gtcggccgac ggcatagagc ttgtcagact ggatgtcaga
    21841 tggaagcaag tccatgacgg tcggaagttc cttgtctttg ttggctgtaa cgacaccagc
    21901 aggtttatga agcataagat aggtgtgttc atagccttga atgattcgat cctgaaaaag
    21961 gagttcttgt agtcctgtat cgatattttg agctagggag cgggctgggc aaccatcgac
    22021 tagaatgtcc cctttgagta aggcttgttt catggccttt cggctgattt tttcttgagc
    22081 taataaatta tctaaacgca tactgtgcct atcttatcat aagtcgcttg ctttgaaaag
    22141 gcttgacgtg aaaagaaaag tggagtgaaa acatttacac ttgcttgagt tatgttattt
    22201 acttgaaatt atggtataat cgttcagtta gaaaataaat tttgaatatt atagaggaaa
    22261 tcatgacaaa attaagagaa gatatccgta acattgcgat tatcgcccac gttgaccacg
    22321 gtaaaacaac cctggttgac gaattattga aacaatcaga aacgcttgat gcacgtactg
    22381 aattggcaga gcgtgctatg gactcaaacg atatcgaaaa agagcgtgga attaccatcc
    22441 ttgctaaaaa tactgccgtt gcttacaacg gaactcgtat caacattatg gacacaccag
    22501 gacacgcgga cttcggtgga gaagttgagc gtatcatgaa aatggttgac ggtgttgtct
    22561 tggtcgtaga tgcctatgaa ggaaccatgc cacaaactcg tttcgtattg aaaaaagcct
    22621 tggaacaaga ccttgtccca atcgtggttg ttaacaaaat cgataagcca tcagctcgtc
    22681 cagcagaagt agtggatgaa gtcttggaac ttttcatcga gcttggtgca gatgacgacc
    22741 agcttgattt cccagtggtt tatgcttcag cgatcaacgg aacttcttca ttgtcagatg
    22801 atccagctga ccaagaagcg actatggcac caatctttga cacgattatc gaccatatcc
    22861 cagctccagt agataactca gatgagcctt tgcagttcca agtgtcactt ttggactaca
    22921 atgacttcgt tggacgtatc ggtatcggtc gtgtcttccg tggtacagtt aaggttgggg
    22981 accaagttac cctttctaaa cttgacggta caactaaaaa cttccgtgtt acaaaactct
    23041 tcggtttctt tggtttggaa cgtcgtgaaa tccaagaagc caaagcgggt gacttgattg
    23101 ccgtttcagg tatggaagac atctttgtcg gtgaaaccat cactccgaca gatgcagtag
    23161 aagctcttcc aatcctacac atcgatgagc caactcttca aatgactttc ttggtcaaca
    23221 actcaccatt tgctggtaaa gaaggtaaat gggtaacctc tcgtaaggtg gaagaacgct
    23281 tgcaggcaga attgcaaaca gacgtttccc ttcgtgttga cccaactgat tcaccagata
    23341 aatggactgt ttcaggacgt ggagaattgc acttgtcaat ccttatcgaa acaatgcgtc
    23401 gtgagggcta tgaacttcaa gtatctcgtc cagaagttat cgtaaaagaa atcgacggtg
    23461 ttaaatgtga accatttgaa cgtgtacaaa tcgacactcc agaagaatac caagggtctg
    23521 ttatccaaag cctttctgaa cgtaaaggtg aaatgttgga tatgatttca actggtaatg
    23581 gtcaaactcg tttggtcttc cttgttccag cgcgtggttt gattggatac tcaactgagt
    23641 tcttgtcaat gactcgtggt tatggtatca tgaaccatac cttcgaccaa tacttgccat
    23701 tgattccagg ggaaattggt ggacgtcacc gtggtgccct tgtttctatc gatgctggta
    23761 aggctacaac ttactcaatc atgtctatcg aagaacgtgg tacgatcttt gtcaacccag
    23821 gtactgaggt ttatgaagga atgatcatcg gtgaaaactc tcgtgaaaat gacttgacag
    23881 ttaacatcac taaggcgaaa caaatgacca acgtccgttc agctactaag gaccaaacag
    23941 ctgttatcaa gacccctcgt atcttgaccc ttgaagagtc tcttgagttc ttgaacgacg
    24001 atgagtacat ggaagtaacg cctgagtcta tccgtttgcg taaacaaatc cttaacaaag
    24061 cagagcgtga gaaagctaac aagaagaaaa aatcagctga ataagagcta gaaagagaga
    24121 aagatggtct atttagtcct aggaatttta ctgctcctac tctatgtatt tgcgacacca
    24181 gaaagcatta aagggacagt caatatcgtc gctatggtat gtattttagt ggcactcttg
    24241 attttattgg ttctatcttt tctgaaaatt tttcaattac caacagaaat attcctagca
    24301 atagccatgt tgatcctagc ttactttagt gtgagagaca tcacactcat gccagtcaaa
    24361 aaaggtaaaa gaagataaaa aagagagttt cggctctctt tttgctagga attttacaat
    24421 agtttgaatt gctttttagt taacaccatc tcttttactt gtatagtatg aatgggaaaa
    24481 acttgaataa aattcgttaa tggcatctat tttatatttg gttagtactg gttgcatatt
    24541 attttgaaat aaaactacta tataatatta ttcatagagg taatatagta aaatatctaa
    24601 aaaattcgat tttttccttg acaacaaata ataaaaatgt tattcttatc acataagaaa
    24661 gcggtttcaa caaaaagaga gaggagggtt tattttgttg cattgttgct caaggtgtgc
    24721 tttttttgaa agaaaaaata aaatgaaaac gaaaaaacat agattacttg ctctagctct
    24781 tatttcaaat tttacattat tgggagctgc atcagctgct gtacaatatc cagatggagg
    24841 agtatggaca tatggagaag attcaggagg tggttaggct ttttcaaatt actatcatgg
    24901 taaaaaatat cattattcat ccatcgtgag cagatgggat ggtcattctg ataaaggaga
    24961 agctcctgct ggaaaaacct cctatgcatg gatttggact aaatggggag aacaagtagc
    25021 attttactgt gattatgacg actaatattt agttttctta gataattccc cttgtaagaa
    25081 attacagggg gaattttgtt tataaggagt ctactatgaa gaaactattc atattattat
    25141 caactttttt tctcagcttc ttccttgctt ggattattgt cttacgtgcg ccacaatatt
    25201 tatatgcaag ctatgattcc gtttctttac ttcgtgtcaa aaaagatact caggaaccga
    25261 cgcgtgaggt atttgaacag gaattggaga attttgcaaa ctcagaacag agtttaatag
    25321 ctagaagaat tgtagagccg agtaaggatg ggacgactca ctttacttat gcaacttatg
    25381 gttagggaac tttaccaaaa gaattccaag aagctagcca agaaagtcgt gaacgtagtg
    25441 atccgctaaa tagttatctc cttttgtcag gctccttgac gaaagaaaag cttgccgata
    25501 aattaggaga tttgggttat aaagcaagtg ctgaccgaaa gataccgccc tattttcttg
    25561 cttttcgaat attactaaat ccccttattt taattagttt agcaatattt ggcttatctt
    25621 tctttgcttt agtgattatc actcggatta aggaaatgag agctgcaggt ataaaactct
    25681 tttctggtca gactctctta tccatcatgg ggcattcttt atcgactgat atcaagtggc
    25741 tccttctatc agccctcctt tccttcctag gtgggggagt cgttcttttt agtcaaggtt
    25801 tgttttatcc tatcttgtta gccacctatg gttttgggat tagtttctat ctgttgtttt
    25861 tattggcgat ttcaatttta ctaatgcttc tttacctaat gagtttgagt tacaaagcat
    25921 tagttcctgt tattaagggg agattacccc ttaaacgcct gatggcttta accctattgt
    25981 gtcagttggt tgctgtcttt acagtaggct acgctgttaa gacgggtttg atgtcttacc
    26041 aacgattgaa agaacttgaa atttcaaaac aagcatggca ggatagagca gactattatc
    26101 aaatttcttt tggcttaggt gatagaggaa aagatacaga aaatcagagc aagtggtatg
    26161 cctttgccaa ggaagcaatc gaagaagaac aagctcttta tgtaaaggat aatctgctcc
    26221 attttgccaa tccacaagga aaaaatgaac agggagagac actggatacc tatagtccag
    26281 atgctaatac gctctatgtt agtcccagtt atttggacaa ggaaaaggtc gtggtagatg
    26341 ctgagaccaa acagaagtta gcccatctcc aaaaaggtga gtttatcctc ttgctcccag
    26401 aacatttgcg ctctcgagaa gcagaactta agaaagtttt tgaagaaaga ttgagttatt
    26461 atggaaaatc tggtgaggag gcaagtgctc ctttggatta tgagatgaaa gcgcacgtta
    26521 gttatctttc aatgggagaa aagcggtttg tttataataa cggtgagaat cccgtatcca
    26581 ctcagtattt gactgatccg attttagtgg cattcacgcc gacttctaca ggtgatagtt
    26641 ttatatcctt atctagttgg tctatcaatg ctggaaaaca actctttatc aaaggatatg
    26701 agagtgggct agaactcttg aagaaagctg gaatttatga gcaagtatcc tatcttaaag
    26761 aaggaagaag tgtttatcta actcgttata atggagttca aactgaaaca acaactttaa
    26821 tcttaggagc tattgtgggg atagctagtt ccttgttact attttattct gtcaatcttc
    26881 tatatttcga gcaattccgc cgagatatct tgattaaacg aatttcaggt ttacgatttt
    26941 ttgaaacaca tgctcagtat atggttagcc aatttgccag ttttgtattt ggtgctagtc
    27001 tctttatttt aagcagtcga gacttggtga ttggcttgct cactttattg gtctttctag
    27061 ctagtgcagt tttgacgctt taccgtcaag cgcagaaaga atctcgtgtt tctatgacaa
    27121 ttatgaaagg aaaataggat gattgaacta aagaatatat ctaaaaaatt tggaagccgt
    27181 cagctatttt cagatacgaa tcttcatttt gaaggtggga aaatttatgc cttaatcggt
    27241 acaagtggct gtggtaagac aacactcttg aatatgattg gacgattaga gccatatgac
    27301 aaaggacaaa tcatctatga tggtacttct cttaaggaca tcaagccttc tgttttcttt
    27361 agagattact tgggatactt atttcaagat tttggcttaa ttgaaaacca aaccgtcaaa
    27421 gagaatctca atctgggttt agttggtaaa aagttgaagg aaaaagagaa aatctctttg
    27481 atgaaacaag ctctaaaccg tgtaaacctc tcttatttgg atttgaagca acctatattt
    27541 gagttatcag gaggagaagc acaacgtgtt gcattagcga agataatttt aaaggatcca
    27601 cctttgatcc tcgcagatga accaaccgct tccttagacc ccaaaaactc tgaggaatta
    27661 ctttccatcc tagaatctct aaaaaatccg aatcggacca ttattattgc gacccacaat
    27721 cctctgattt gggagcaagt ggaccaagtc attcgagtta ccgatttatc acatagatga
    27781 taaggcaaga ttcagttaga agaaagagtc acaaacacac tttgtggctt ttttatttcc
    27841 ataaaaatgg taaaatagta ggagtagaaa tggagttcga gacatgaaag taatagatca
    27901 atttaaaaat aagaaagtcc ttgttttagg tttggccaag tctggtgaat ctgcagctcg
    27961 tttgttggac aagctaggtg ccattgtgac agtaaatgat gggaagcctt tcgaggacaa
    28021 tccagctgcc caaagtttgc tggaagaagg gatcaaggtc attacaggtg gccatccttt
    28081 ggaactcttg gatgaagagt ttgcccttat ggtgaaaaat ccaggtatcc cctacaacaa
    28141 tcccatgatt gaaaaggctt tggccaaggg aattccagtc ttgactgagg tggaattggc
    28201 ttatttgatt tcagaagcac cgattattgg tatcacagga tcgaacggta agacaaccac
    28261 aacgactatg attggggaag ttttgactgc tgctgggcaa catggtcttt tatcaggaaa
    28321 tatcggctat cctgccagtc aggttgctca aatagcgaca gacaagaaca cgcttgttat
    28381 ggaactttct tctttccaac tcatgggtgt tcaagaattc catcctgaga ttgcggttat
    28441 tactaacctt atgccaactc atatcgatta tcatggatta tttgaggaat atgtagcagc
    28501 caagtggaat atccagaaca agatgacagc agctgatttc cttgtcttga actttaatca
    28561 agacttggca aaagacttgg cttccaagac agaagccact gttgtaccat tttcaacact
    28621 tgaaaaggtt gatggagctt atctggaaga tggtcaactc tacttccgtg gtgaagtagt
    28681 catggcagcg aatgaaatcg gtgttccagg tagccacaat gtggaaaatg cccttgcgac
    28741 tattgctgta gcaaagcttc gtggtgtgga caatcaaacc atcaaggaaa ctctttcagc
    28801 cttcggtggt gtcaaacacc gtctccagtt tgtggatgac atcaagggtg ttaaattcta
    28861 taacgacagt aaatcaacta atatcttggc tactcaaaaa gccttgtcag gatttgacaa
    28921 cagcaaggtc gtcttgattg caggtggttt ggaccgtggc aatgagtttg acgaattggt
    28981 gccagacatt actggactca agaagatggt catcctgggt caatctgcag aacgtgtcaa
    29041 acgggcagca gacaaggctg gtgtcgctta tgtggaggcg acagatattg cagatgcgac
    29101 ccgcaaggcc tatgagcttg cgactcaagg agatgtggtt cttcttagtc ctgccaatgc
    29161 aagctgggat atgtatgcta actttgaagt acgtggcgac ctctttatcg acacagtagc
    29221 ggagttaaaa gaataatatg aaaaaaattg tctttacagg tggggggacg gttggacacg
    29281 ttaccctcaa tcttttgtta atgcccaagt tcatcgaaga tggttgggaa gtccactata
    29341 tcggggacaa gcgtggtatt gaacaccaag aaatccttaa gtcaggtttg gatgtcacct
    29401 tccattctat tgcgactgga aaattgcgtc gctatttctc ttggcaaaat atgctggacg
    29461 tcttcaaagt tggctgggga atcgtccaat cgctctttat catgttgcga cttcgtccac
    29521 agaccctttt ttcaaagggg ggctttgtct cagtaccgcc tgttatcgct gcgcgtatgt
    29581 caggagtgcc tgtctttatt cacgaatctg acctgtctat gggcttggcc aataaaatcg
    29641 cctataagtt tgcgactaag atgtattcaa cctttgagca agcttcgagt ttgtctaagg
    29701 ttgagcatgt gggagcagtg accaaggttt cagatcaaaa aaatccagaa ccagatgaat
    29761 tggtggatat tcaaagccac tttaatcata aattgccgac tgtattgttt gttggcggtt
    29821 ctgcaggtgc tcgtgtcttt aaccaattgg tgacagacca taagaaagaa ctaacagagc
    29881 gctacaatat tatcaatcta actggagatt ctagcctgaa tgagttgagc caaaatcttt
    29941 ttcgtgttga ctatgtgacc gatctctatc aacccttgat ggaattggct gatattgttg
    30001 tgacacgtgg tggtgccaat acgatttttg agctcttggc gatagcaaaa ttgcatgtca
    30061 ttgtgccact tggtcgtgaa gctagtcgtg gtgaccagat tgaaaatgca gcttactttg
    30121 ttaagaaagg ctatgcagaa gaccttcaag aaagcgattt gaccttggat agtttggaag
    30181 agaagctttc tcacttacta agtcacaagg aagattacca agctaagatg aaagcttcta
    30241 aggaattgaa atctctagca gatttttatc aattgttgaa aaaagattta tcataaggaa
    30301 agtaaatgtc aaaagataag aaaaatgagg acaaagaaat cctcgaagaa ttgaaagagt
    30361 tatcagaatg gcagaaacga aaccaagaat atctaaaaaa gaaggctgaa gaagaagcgg
    30421 ctctagctga ggagaaggaa aaggaaagac aagctcggat gggagaagaa tctgagaagt
    30481 cagaggacaa acaggaccag gagagtgaaa cagaccagga agattcagaa tcagctaagg
    30541 aagagtctga agaaaaagta gcatcctcag aggctgacaa agagaaagaa gagaaagaag
    30601 aatcagagtc taaagagaag gaggaacagg ataaaaagct tgctaaaaag gctacaaagg
    30661 aaaaaccagc caaagcaaag attcctggta tccatatctt gcgagccttc acgattttat
    30721 ttccaagtct gcttttattg attgtctctg cctacttgct cagtccttat gcgaccatga
    30781 aagatattcg tgttgaggga acggtgcaaa ctacagctga tgatattcga caggcttcag
    30841 gcattcagga ttcggattat acgattaacc ttctgctaga caaggcaaaa tatgaaaagc
    30901 agattaagtc taactattgg gttgaatcag ctcaacttgt ctatcaattt ccaactaagt
    30961 tcactattaa ggtcaaggaa tatgatattg tggcctacta tatttctggt gaaaatcatt
    31021 atcctattct ttccagtggt cagcttgaga ctagttctgt gagtctgaac agtttaccag
    31081 aaacttattt atcagttctc tttaatgata gtgaacaaat caaggttttt gtctcagaac
    31141 ttgctcaaat tagcccagaa ctcaaggcgg ctatccaaaa ggtggaatta gccccaagca
    31201 aggtgacatc cgatttaatt cgattgacca tgaatgattc ggacgaagtc ttggttcctc
    31261 tatctgaaat gagtaagaaa ctgccatatt acagtaagat taagcctcaa ttgtcagaac
    31321 cgagtgtggt cgacatggaa gctggaatct acagctacac tgtggcggat aaattaatta
    31381 tggaggctga ggaaaaagcc aaacaagagg ccaaggaagc tgagaaaaaa caggaagaag
    31441 aacagaaacg tttagaagaa gaacagaaaa aacaagagga agagagcaat cgaaaccaaa
    31501 cgacccagcg ctcatcgcgt cgctaggttt accttttctc ttatagttct ttagtgacca
    31561 tgtttttact tgacaagtgc tagtagaaat aatagaatag taaaaaacct ttaaagcagt
    31621 ccagagaggc agctaaggtt agacggtgaa agggtggaga ctacccattt ttcgtggaac
    31681 cttgctgttg gcaggttcct tttttcgtgg cttctgttgg ccagactctc tcactagtaa
    31741 aggtaaaagg agaaacctat gcgagaacat cgtccaatca ttgctcttga ttttcctagt
    31801 tttgaggcgg tcaaggaatt tttagctctt ttcccagcag aagaaagcct ttatctcaag
    31861 gtagggatgg agctttatta cgcagcgggg cctgagattg tgtcctactt aaaaggtttg
    31921 ggtcatagtg tctttttgga tctcaaactt catgacattc ctaatacagt caagtcagcc
    31981 atgaaggtct tgtctcagct tggtgtcgat atgactagtg tccatgcggc tggtggtgta
    32041 gagatgatga aggcggcgcg tgaaggtctt gggagtcaag ccaaattgat cgctgtaacg
    32101 cagctgacat caacgtcaga agcccagatg caggagtttc aaaatatcca aaccagtctg
    32161 caagagtctg tgattcacta tgccaagaag acagctgaag ctggcttgga tggtgttgtt
    32221 tgctcggctc aggaagtaca agtcatcaag caggctacca atccagattt tatctgtctg
    32281 acaccaggga ttcgtccagc tggtgttgca gttggagatc aaaaacgagt catgacacct
    32341 gctgatgcct atcaaatcgg cagtgactat atcgtagtgg gacgtcccat tacccaagct
    32401 gaggatcctg ttgcagctta tcatgccatc aaggatgaat ggacacagga ctggaattaa
    32461 agaactagat tagaaaaata aaaggagaat accatgacac ttgctaaaga tatcgctagc
    32521 cacctcttga aaatccaagc cgtttacctc aaaccagagg aacccttcac ttgggcatct
    32581 ggtatcaagt caccgattta cactgataat cgtgtgacac tagcctatcc agaaactcgt
    32641 accctaattg aaaatggttt tgtggaagct atcaaagaag cctttcctga agtagaagtg
    32701 attgcaggaa ctgcaacagc agggattcca cacggagcca ttattgctga taagatggac
    32761 ttgccttttg cctacatccg tagcaaacca aaagaccacg gagctggtaa tcaaatcgaa
    32821 ggtcgcgtag ctcaaggtca aaaaatggta gtggttgaag accttatttc aacgggtggt
    32881 tcagttcttg aagctgtagc agcagccaag cgagaaggag cagatgtact tggagttgta
    32941 gcgattttca gctaccaatt gccaaaagca gataagaact ttgcagatgc tggtgttaaa
    33001 cttgtgacgc tttcaaacta tagcgagctt atccatctag cccaagaaga aggttacatc
    33061 acgccagagg gccttgatct tctaaaacgc tttaaagaag accaagaaaa ttggcaagaa
    33121 ggttaggtca gtaagataaa gagagacgag gctaccgagt ctcttttacc attttattta
    33181 aaatatgaca atattttaaa taaaataatt gacaacgctt tcttttattg atataatgaa
    33241 aatgtaatat gtatcaaatt gatcaatcaa ctatcttgtt tatcacttct taagaggacg
    33301 atgtcatgaa aagaagaaaa atatattcct tttttgcgta gttacaattg catctagttt
    33361 gtttctccct acagttttag ctagacagat tggaaattat gatttaacgt tgccgcgttg
    33421 gggttcggat acaactagtg agcttgagaa agaaaacgcc tctgctggaa ttaataatag
    33481 tgacagcact ggtggcggta aaaggttaag tacctctatt cgtagcgcct atagtgggtc
    33541 agatattacc ccggtatatt cattggggtc tggctctagg attgtcatgt actataatgg
    33601 aggtggtgac aattatattg gttctggtac tagattagct atggcgccac aatttggaaa
    33661 tcatgtaaga attcatactt caggttcttg gagtccagat tcttattaac ttacttgtca
    33721 gagtaagcct taaagatggt tgattgtggg tgtagcatga aaaaagaatg ctacacccta
    33781 tttttattat aaggaggagt aaggatggaa tttttcattt gtaatcttgt acgagtcgtt
    33841 caatcacctc gattttatat gtctttattt ttgacccttc tttgcatgag tttaggaaat
    33901 ttccttgctt tcaatggtat ttataaaatt gaaggtttat cgattttttt tgccgcttct
    33961 tctattcgag gattttcacc gattagccta gtagctgcac ttatctgtac actgccctat
    34021 tctagtcaga taatagagga tgctgagagt cattttctaa cagcacaatt gtgccgaatt
    34081 tctaaaaaga ggtatctagc tattgtaggt agtactgcaa ttatttcttc ttttctagtc
    34141 ttttttctcc cctatttatt attattagga attaatcttt tagtgactcc ttatcaggaa
    34201 atttatattg gagcttatag tggtgcctta aaagaattat ttgattctaa tcagttgctc
    34261 tatagtcttg tgacgactct ttggtatgga gtttggggcg ctgtgttctc tatttttgga
    34321 ctagctagtg ctttgctagt gaagaaaaaa ataggagcta ttttcatccc agttacctat
    34381 atgatggttg gtggtatttt ttgggctatt ttagggctat cttacttaga acctgtgaca
    34441 acattagctt tgggatatca gaaagatatc agtctttcct tagttagtgg gcatcttgct
    34501 tttattttat ttgttagttg tttggttgtt tatggtacat tttttctaca ttcagaggac
    34561 tatgtataat gaaacaattt gttcaatttt ataaaaaaga tttcttagca gtattggttt
    34621 attttatatt actgctatcc tgtgttttat ctagtacagt atatttattg cgctgtcgcc
    34681 aatattcaat ccatccaaat gtattagaat ggatcttagt tttacttcaa gatatgacga
    34741 ctggagtata ttgctttccg ttcacatata tattgttctt tttttatttg atgaataact
    34801 attttaatag gttggagtgt cgcattcgtc tgaaatcaat taagcacttt accagtttta
    34861 gtttcaaatt agcagctctt agtacgggga tttggacggc gactttattt ttattgattt
    34921 ttctaattgc atttagtaat ggttttagct tctctttgga gataaaggag gttgattttt
    34981 taagagaatt ttatggtata agtattgcaa acaatgctag tttctttata ggattttttt
    35041 tctcttatat agcatactat ttctttttat ccttacttac tattagcagt ttttcttggt
    35101 ttaaaaaatc aaacatgagc ttagtatttc tgtttacttt tttatttgta gaatccttat
    35161 tctggattta tcagttgaac aatgggataa ttggattatt gccaattttt cagtatatgg
    35221 taaattccaa tccgtatgca ttgatttatt ggcttacatt actatctatc ataattccat
    35281 tgactgtatt ttctgttcat agaaactgga ggagagtgta aaagttggaa atgggaaagt
    35341 taagtagtca catgtggaga ttgaatcaga taatctatac caagtacttt tggggttatg
    35401 ttcttttttg gatattgatt tgtttagaat tatggtattg gttagaagga aatgatagac
    35461 ttgttataga aattttaaaa gggcctaatc tgagtcaaaa ctctttttta gtcttatcta
    35521 tatggttgct tcattggttt attattcata cattttttct agcagttgta tatcgtagaa
    35581 gagcatccga tttctttctg gaagtgattc gattttcttc tattaagctc tggattaggt
    35641 atcagatttg gacctgtttt ctttatggac ttattttaat catggtaaaa gttctagtga
    35701 ttcaatttat gttacagtta ccaaactggg atataggagt tttgtttata gttgattctt
    35761 tgaatgcttg tgtgctatcc ttgctttgct ttatgttata cgcactagga gcgaatgtac
    35821 aaatgaactt tgcttgcgtt agtttctttt tactcatgat tgtgtttggt ggtctatttg
    35881 taggaaatcg aactaattat ctattttata ttttgaatcg agggaatgga gatataggac
    35941 gagatttatt tcttcagttg ctatttttag tctttctttt taaaagcatt ttctatttca
    36001 ctcgtcaaaa gaggaggttt atagaatgaa tgaaataatt acattaaaaa atattgagtt
    36061 gaaattaaaa aaaacatgtg tttttcaaaa ccttaacttt agttgtaaac agggggaaat
    36121 tataggaatt actggtgcga atggctcagg gaaaagtgta ttgtttaaat taatagctgg
    36181 tttatatagt ccgtcttatg gagaagtgtt aatcaatggg gaaaatattg ttcctgagag
    36241 aaaaattcca gctaatttgg gagctttgat tgaagaacct ggttttataa attattatag
    36301 tggctttaag aatttacaat atttggcaag catacgagga gtagttggta atcaggaaat
    36361 caatgataca ctgaaaatag ttggtctata tgagcaaaaa gaccagaaag ttaaaactta
    36421 ttcgctaggt atgaggaaaa agctagggat tgctcaagca attatggaga atccctctat
    36481 tcttttacta gatgaaccta tgaatgcctt ggataaatca agtgtagaaa atatgagaac
    36541 attgtttaga aagctctcta gtgaaaaagg gacaacaatt ttgattgcta gtcatagtga
    36601 agaggatatt cgtatcttat gtgataaagt atatgcaata gaagataaag tatgtacact
    36661 gtgttcagat tgaacatctt agatagactc aggatgttat aggtaaaatc ttaaaaaggg
    36721 attggagctt aaaatccagt cccttttaag agttaatggc caccttcaac aaccaggtca
    36781 tctgctttag cagcgtcacc gtaggttggg tgaagtgttt tttcataggc cttgtggaag
    36841 aagttttcct tgcctaattt ttcaatatct ttattgatga agtctagcaa ttcttggttg
    36901 cctttttgaa ctgctgccgc aatggtatcg ggatcaccga gggaagtaat tcctacttca
    36961 aatcctttat tttcaagcgc ccaagctaga acttccgtat tgtcagttga aaaggcatct
    37021 ccacgtccgt caagaagagc ttggtaagag tcactgtatt ggtcgtattt ttggagtttg
    37081 atttctggat gattcttttc aaaataagtc tcagcagtcg ttccttttgt gacaattaag
    37141 gttttacctt caagttgttt gacgtctgta atgagaccag tcttaggtga tacgacaccc
    37201 agagaaactt tcatatatgg aagggcaaaa tcaacttgtt tcttacgttc gtcagttact
    37261 gtaaagttag caagagtaat atctaccttg tttgaaatca agtattccgc acggttggca
    37321 gcatcgactg aaatgtattt aaccttgaca ccaaggtctt gagctagttg gttccctagt
    37381 tcaatatcgt agcgtagcct tggtaagaac catcattgtc aacgtagcca aacggttttt
    37441 tatctccaaa cacggcgatt cgcagttcac cgcttttttt gatttcatcg atagtgcgag
    37501 ctttggcagt tgtttttcca gaggatgaac cagcgtttcc acctgagcta caagcagtga
    37561 taaagataag ggcaaaggca agtgctaaaa cagttaagag tggtttgaat agtttcataa
    37621 gaatctcctt tatagatatg agccgaattg gctaaagtca aagacgttta aaaattcctg
    37681 ggctcgtttg gtttgcggat tggtaaagaa ggcttgagct gttccttctt cagcgatttt
    37741 cccttggtcg aggaagataa tccggtcagc aatggcttgg gcaaactgca tttcgtgggt
    37801 tactaaaatc atggtacggc cttcttgggc caaatcattg ataagttcca gcacctcacg
    37861 caccatttct ggatccagcg aagcagtcac ctcgtcaaaa aggatgattt ctggatgcat
    37921 taggagggca cggacaattg caacacgttg cttctgtcca ccagataatt gacgggcaaa
    37981 gctatgttgt ttatccagca aaccgacacg atctagtaat tgcaaagctt cttccgttac
    38041 ttctttcttg tcccttcctt gagttttgat agggcctagg atgaggtttt gtaagacatc
    38101 cagatgggga aagagttcat aactttgaaa gaccatgcca atcttttggc gaactaggtg
    38161 aaaatctttt ttattttcaa cgatagactg accatccaga agaatatctc caccttgaat
    38221 actttctaag ccgttgaggc aacgaaggag ggtacttttc ccacaaccag atggccctag
    38281 gatgacaaca acttcccttt tttgatttct agagaaagtc cttggaggat gggattgtct
    38341 ccgaaggatt tttttagttc cttgatttct aagatagttt cagacattta gtttctccaa
    38401 tgtttttcta agtgagtgga tagtttggaa atagggtagc aaactgcgaa atataagact
    38461 agaatggttc cataaatcca aaatgaagca gttgggatgg tcaggcgatt gctatcgatg
    38521 atttgttgtc caactttggt cacttccaca accccaatca aaacaactaa tgaagtggtt
    38581 ttaatcatcc gagtgacaag attgatagcc tgcggtagca gtcttcttaa gacttgtggg
    38641 atgatgatgt ggtagtaaag ttgaacatta gtcaagccga gtgcctgtcc actttcaaac
    38701 tgatgtttag ggagagaagt gatagctcca cgtaccaagt ctcccatttc agctgttccc
    38761 cagagggtaa aaacgataat agctgaagtc tcacctgaga tattgatatt aaagtttcga
    38821 gctaagccaa agtaaacgat gaagagtagc accagctggg gcatgatacg ggtaaagtcc
    38881 agatacaatc gtgttaaaaa tcgtatgatt ctagaatggg aggtcatgat gattcccatg
    38941 actgttccga acatcatgga taagaggaca gacaggatgg atatctcaat cgtaacgcac
    39001 aatccctgta agattctcag gagattattt ccctgaaaga gtacttggat tcccgaatcc
    39061 tgcatggcgg agcctccttt ctatccagct aaagaccagt gagatgggta gcagcatgat
    39121 cagataagca actaccaaca tagctagcgc aatgtctgtc tcatagtaga gaccaatcaa
    39181 atccttggcg acatacatga ggtcggccaa agccactgct gagaaaacag aggtttcctt
    39241 gataaggaaa atgacattgg cactaaagga ggggagtgcc accgctgttg cttgcggaag
    39301 aaccacatag cgaaagacct gtagaggtgt cagaccaata gcgaggccaa tctcctgctg
    39361 ggtttgactg atggcttcca gcccacttcg gaaagattct gccatatagg atcctcctaa
    39421 aaagacaagc ccaagcgttg cacagacttc tgaagatagg acaatcccga ttcggggaag
    39481 accgaagtag agaaagaaga gttgaatcaa aaggggcgta ttacgtgaca attcaatgta
    39541 ggctgtcgct acttgcgcca aaacagggat tcgataatgt cggatgatac taacgattaa
    39601 accgagcaga aaggatccca aaattcccca aactgcaata tgcaaggtca gaaagaatgc
    39661 cttttgatat agtggtagat attgttcaac aatggaccaa tccaaaaata gaacctccca
    39721 tctagaaata atacagttat tgtagcactt aaaatcttct ttggataata tctatttttt
    39781 attgccgtta taaggatttt ttaccataga cataaaattt ctgaaatttc caaacaaaat
    39841 atttgaaaag ttttgaaaaa aagttaagat atttttgtaa tatacaaagt aaacgcttac
    39901 ttattaagga ggacagttta tgtcatacaa aacaagcaat gcagaaggtc atgtagattt
    39961 catcaatacc tatgatttgg agacaatggc gcaacaagtt attcctaaag cagcatttgg
    40021 ctatatcgct agtggggcgg gagatacttt cacttctttc cagtgatttt agcgtcaggt
    40081 tctttttagt ttttaaagat tatccgtgaa tttcttgctt atttatgata aaatgggagt
    40141 atcgcaaaaa atgactcatc gtattcaatt ttgagtaaaa ctaggaggat cccatgtcta
    40201 cagaacatat ggaagaacta aatgaccagc agatcgttcg ccgtgaaaaa atggctgcgc
    40261 tccgcgaaca aggaatcgat cctttcggaa aacgttttga acgtactgca aattcacaag
    40321 aattaaaaga taaatatgcc aacctcgata aagaacaatt acacgataaa aacgaaacag
    40381 ctactatcgc aggacgcttg gtaaccaaac gtggtaaagg aaaagttggt tttgcccacc
    40441 ttcaagaccg cgaaggccag attcagatct acgttcgtaa ggatgctgtc ggtgaagaaa
    40501 actacgaaat cttcaaaaaa gcagaccttg gtgacttcct tggtgtcgaa ggtgaagtga
    40561 tgcgtacgga tatgggagaa ctctctatca aggcaaccca catcacacac ttgtctaagg
    40621 ctcttcgtcc tcttcctgag aaattccatg gtttgacaga cgttgaaaca atttaccgta
    40681 aacgttacct tgacttgatt tctaaccgtg aaagctttga acgctttgtc actcgttcaa
    40741 aaatcatctc tgaaatccgt cgttaccttg accaaaaagg attccttgaa gtggaaacac
    40801 ctgttcttca taatgaagcc ggtggtgctg ctgcccgtcc atttatcacc caccacaatg
    40861 cccaaaacat tgacatggtg cttcgtatcg cgactgagct tcacttaaaa cgccttatcg
    40921 tgggtggtat ggaacgtgtc tatgaaattg gccgtatctt ccgtaacgaa ggaatggacg
    40981 ctactcataa ccctgagttt acttctatcg aagtttacca agcttatgca gacttccaag
    41041 acatcatgga cttgacggaa ggcattatcc aacacgctgc taaatcagtt aagggcgatg
    41101 gcccagtcaa ctaccaaggt actgaaatca agattaacga accatttaag cgtgttcata
    41161 tggtggatgc tatcagagaa attactggtg tcgatttctg gcaagacatg actttagaag
    41221 aagctaaagc tatcgctgct gagaagaaag ttccagttga gaaacactac actgaggttg
    41281 gtcacatcat caatgccttc tttgaagagt ttgttgaaga aactttaatc caaccaacct
    41341 ttgtctatgg acatccagta gctgtatctc cactcgctaa gaaaaatcct gaagaccaac
    41401 gctttactga ccgtttcgag ctctttatca tgactaagga gtacggtaat gcctttactg
    41461 agttgaacga cccaatcgac caacttagcc gttttgaagc ccaagctaaa gctaaagaac
    41521 ttggtgatga tgaagcgaca ggcatcgact atgactacat cgaggctctt gaatacggta
    41581 tgccaccaac aggtggtttg ggaatcggta tcgaccgtct ctgcatgctc ctcactgata
    41641 caacaactat ccgtgatgta ttgctcttcc caacaatgaa ataaattctt accctctggc
    41701 tcttaccagg ggattttttg attcaaaaag agactgaatt taaggagaaa atgaagtgta
    41761 gtatattgaa gttgaaatag tacactttga tttctaagac actgttagaa attggtttaa
    41821 attccctaat caatttgtgc atgttttatt tcattttacg atagtacgct gaaacttttc
    41881 aaaaagtact agaaattgac ttggattccc caattgattt gttcagattc actataaata
    41941 aaaaattaat aagtgggata ggaagttagc gtcaactagg atagtatctt gcttaaacag
    42001 tatatatggg actgatataa gtccataggt cctattagag gatgttctgg tgtcttattc
    42061 acttgttttt tatagtatta gtagatagaa tcagcaaata aaaaagtagt tcaaatgcct
    42121 ggcagcaaaa aatctcaacg attcacttaa tatagactaa ggtttagagt ttaaggaaag
    42181 tagggctagt atattgtatg aaaaaataag atggttttta agcaaaactc ttgaaaatga
    42241 ttgaaaaaag agttattata gttgtatagt aaaaagcaaa cgcttactta atcgaggagg
    42301 acagtttatg tcatacaaaa caagcaatgc agaaggtcat gtagacttca tcaataccta
    42361 tgatttggag ccaatggcgc aacaagttat tcctaaagca gcatttggct atatcgctag
    42421 tggggcggaa gatactttca ctttaagaga gaatatccgc gcctttaacc acaaactcat
    42481 cgttcctcat acactttgcg atgttgaaaa tccaagtaca gagattgaat ttgcaggtga
    42541 aaaactatct tcgccaatca ttatggcacc tgttgcggct cataaattgg caaatgaaca
    42601 gggggaagtg gcgactgcgc gtggtgtgca tgagtttggt tctctttata caaccagttc
    42661 ttactctact gttgaccttc cagagatttc tgaagccctt caagggacac ctcattggtt
    42721 tcaattttac tttagtaagg atgacggtat caaccgccac atcatggacc gtgtgaaggc
    42781 tgaaggttat aaagcgattg tcttgacggc agatgctact gtagggggga atcgtgaagt
    42841 ggataagcgt aatggttttg tcttcccagt tggcatgccg attgttgaag aatacctgcc
    42901 agaaggtgct ggtaaatcaa tggactttgt ttacaaatca gctaaacaac gcttgtctcc
    42961 acgcgatgta gaatttatcg ctgaatactc tggtcttcct gtgtatgtca agggaccaca
    43021 atgccgtgag gacgttgaac gttcgcttgc tgcaggagct tctggtatct gggtaaccaa
    43081 ccacggtggt cgtcaaatcg acggtggacc agctgccttt gactcgcttc aagaagtggc
    43141 agaagcagtt gatagacgtg tgccgattgt ctttgactct ggtgttcgtc gtggtcaaca
    43201 cgtctttaaa gccttggctt caggagcaga cttggtagct attggtcgcc cggttattta
    43261 tggcttggct ctcggtggta gtgtcggtgt gcgtcaagtc tttgaacact tgaatgcgga
    43321 attgaagaca gttatgcaat tgtctggagc tcagaccatt gaagatgtca aacactttaa
    43381 gctccgtcac aatccataca acccaacctt cccagttgac cctcgtgact taaaattgta
    43441 ttgataaaac agattgcctc cactgaatgt ggaggttttt cttcgtgtat tggaagaata
    43501 aatcgctatc gaaaaccata gtaaaatgga ataaaaacag gacaaatcaa tcaggatatt
    43561 taaatcgatt tctaacaatg ttttagaagt agaggggtac tattctagtt tcaatctact
    43621 atatataaag atatttttcg gttaaatatc ttgctaaggc tttcattttt tgctatactg
    43681 gttcagtaat taaataatag agacatttgg ggtgctttaa gctgagatga tacccattga
    43741 acctgataca gttaagactg gcgaagggaa atgtgaaacg ttttttcgta tggcgaaatg
    43801 aacgatctaa tcttgtaagt caactctaat tcttgattgt aattggagtt ttttgtttat
    43861 ataaactgga taggcttgtt tagttagctc tctgcaaatg ctctcgatgt gctttaaaag
    43921 gatcaagtgg aattacgatt ttgcttgata tttcttggtg ttttattaat tactaacaag
    43981 taaagagagg agaagtaaat atggaaacac aagactatgc atttcagcca ggtttgactg
    44041 ttggagaatt attaaaaagc agtcagaagg attggcaggc tgcaatcaat catcgttttg
    44101 ttaaggaact ttttgcgggg acaattgaga ataaggtctt aaaggactat ctgattcaag
    44161 attatcactt ctttgatgcc ttcttatcca tgctgggtgc ctgcgtagct cacgcagata
    44221 aacttgaatc caagcttcgt tttgccaagc aactaggctt tcttgaagca gatgaagatg
    44281 gttatttcca aaaggctttt aaagagttaa aagtagcaga gaatgactat ctagaagtga
    44341 ctttgcaccc tgtaacaaaa gcctttcagg atctaatgta ttcggcggtg gcttcatcag
    44401 actatgccca tcttttggtc atgctggtca ttgcagaagg tctctattta gactggggtt
    44461 ctaaagattt ggctttacct gaagtctata ttcattcgga atggatcaat ctccacagag
    44521 gtcctttctt tgcagagtgg gttcaatttc tggttgacga actcaatcgt gtcggtaaaa
    44581 atcgagaaga tttgacagaa cttcagcaac gctggaatca agcagtcgct ttagaattag
    44641 ctttttttga tattggttac gatgtctaga gaaagctcat gatatttaca aatttgatga
    44701 ggtaagactc ttcgaaaatc tcttcaaacc acgtcagttc tatccacaac ctcaaaacag
    44761 tgttttgagc aacctgcggt tagcctccta gtttgctctt tgattttcat tgagtataaa
    44821 tcattcaatg taaatgaaaa aaattcttaa cgaaagatag aaataaatcg aaatcagtag
    44881 atcgtataaa gtgaaaagga aggatttcaa tatgacaagt ttaaaattat taaaagaaaa
    44941 agcaccattg gtcatttgta taaccaatga tgtagtaaaa aatttcacag caaatggatt
    45001 agtagcactg ggcgcctcac cagccatgag tgagtttcca gcagatttag aggatttgtt
    45061 aaagtatgct ggtggtttat taataaacat aggaacattg acagatgaaa attggaaatt
    45121 ataccaagct gctctgaaaa ttgcagagaa atataatgtc ccagcagttt tagatcctgt
    45181 agcctgtgga gcaggagaat atagaaaaaa agtagcagat gatctaatca acaattataa
    45241 actagcagcg attagaggaa atgctggcga gattgcctct ttagtaggaa tagatgtggc
    45301 atctaaagga gtagatagtg cgggcgtaga taatattgac gaaattgctc tagcagcaaa
    45361 tgagaagttc aatattccaa tagtagtaac aggtgaagtg gatgccattg ctgttaatgg
    45421 agaagtggta acgattcata atggtagtgc tatgatgccg aaagtcattg ggacaggatg
    45481 cttattaggg gcagtggtag caagctttat cggactagaa aaaggtcaag aattgaaatc
    45541 attagaaaca gcaatgttgg tttacaatat cgctggagaa atggcagaaa aacgtccaaa
    45601 tggacatctt cctgggacat ttaaagttga atttataaat gccttatacg agattacaga
    45661 tgaagatgta aaggaattca aaagagtgaa gtaagatgtt tcataaagaa ttactaaaac
    45721 tatattttat ttgtggaacg actacttgcc aaggaaaaaa tctatataca gtcgttgagg
    45781 aagccttaaa aggtggtata accttatttc aatttcgaga aaaaggtgag ggtgctttag
    45841 aaggcttaga aaaacttgag ctagctatcc aaattaaaga actttgtaaa aaatacaatg
    45901 tgccgtttat cgttaatgat gatatcgatt tggcaatgga aattgacgct gatggcgtac
    45961 atgtaggtca agatgatatt ggtgttgatg aaattagaaa attgatgcca gataaaataa
    46021 ttggtctttc tataaaaaac gaggaagaat ttcaacaatc aaaagttgaa tatgtagatt
    46081 atgttggtgt tggtcctgta tttgataccc agtcaaagga tgatgctggt ggtgctatag
    46141 gttatgaagg tcttgaattg atgagaaaac tattgccaca aatgccttta gttgcaattg
    46201 gtgggataca gacgaaacat attaaagaca ttataaagac caatgttgac ggcgtttcaa
    46261 tcatttcggc aatatcgtat gcaaaaaata tagaaaaaac tgttcgggaa atgagtgaac
    46321 aatagatatc tatccttgga ttctaagtaa gtaggatttt ccttttttaa aaagctatgt
    46381 ccagattcag cttgaatggc taattcatca aacaggtcat ttgttttttg caaaagaaag
    46441 atctgctgtc tttgtgagtg caaggctgta tttccagttc aatttcttga actagtataa
    46501 aatgtgtgtt ataataatca cataattaaa taataaagac atttggggtg ctttaggctg
    46561 agatgatacc cattgaacct gatacagtta agactggcga agggaaatgt gaaatgtttt
    46621 tttcgtatgt cgaaaagaac tgtctaatct tgtaagctga actctaattc gtatctgtaa
    46681 ttagagtttt ttcttttacg aaactggatg aagatgatat agtagattga aataagatgc
    46741 gaacaaatca attagaaaat tcaaattaat ttctagaaat attttagcat tcttgtgtac
    46801 tgttctaaat tcagtctgct atacaaagta tttaggtcgg tcttcttgag tgtcccactt
    46861 ttctttaaaa aaggagtttt ttatgttgaa aaaatggcag ttaaaagatg ttatcttgct
    46921 tgctttcttg tctatctttt ttggtggggt tttcgttggt tcaggatatg tgtataatat
    46981 tttcagtcta ctcttaacac ctcttggttt gcaggccttt gccaatgaaa tcctcttcgg
    47041 tctctggtgt atggctgcgc ccattgctgc catctttgtt ccgagagtcg gaagtgcaac
    47101 gattggagaa gtgctagctg cgcttgctga agtcctttat ggtagccaat ttggtctagg
    47161 agctcttttg tctggctttg ttcaaggttt gggaagtgaa tttggtttta tcgtaactaa
    47221 gaatcgctat gaaagttggc tctctctaac tgctaatagt attgggatta cgcttgttag
    47281 ctttgtctat gaatacatta agttaggtta ctacgccttt tcccttccgt ttgtcctttc
    47341 cttgcttgtg gtacgtttta tttctgttta tttcttctgt accatcttgg ttcgtgccat
    47401 tgtcaaactc tatcatcagt ttgcaactgg aggaaaagca tagatgggtc tggaactacg
    47461 agcgattcag tccccaatct tctctgagcc gtttgatttt acttttcatg cgcaagcctt
    47521 taccttgtta gttgggagca gtggttcagg aaaatccagc ctctttcaaa tgattgccca
    47581 agtcagttct cttccctata gtggtcaagt cctgatagat gggagcgagg tcagtcagct
    47641 ttctatcatc gcacgtgtcc agaaggttgg cattctcttt caaaatccca atcatcaatt
    47701 taccatggag aacttgtttg aggagctgat tttcaccttg gagaatatcg gctatcacct
    47761 tcaggaaatt gattctaaaa tagcagaggt tgtccagcaa tgtcgttgcg aggcaatctt
    47821 acaccgtccc attcatcacc tatcaggtgg ggaaaagcaa aaggcgacct tggctgtcct
    47881 ctttgccatg aatcctaggg tctatctctt ggatgagccc ttcgcttcca ttgaccgcaa
    47941 gagtagaatc gagatattgg agattctaaa agagttggct cttgatggga agacagtcat
    48001 tttgtgcgac catgatttat ctgactataa agcctatatc gaccatatgg ttgagctaag
    48061 agacggaaaa ctaagggaag tgtttcaaat cccttcctat gagatgacac aggttgcttc
    48121 aaaggaagtt gcttctagcc cggaattatt ccatatgaac cgtgtgactg gtgagcttgg
    48181 taatcgcccc ctcttttcaa ttgctgattt cacattctat caagggattt cctgtatcct
    48241 gggtgacaat ggtgtcggga aatcaaccct ctttcggtct attcttcaat ttcaaaagta
    48301 taaggggagc attacttgga agggttcggt cctgaaaaag aaaaagagtt tgtaccgtga
    48361 tctgacgagt attgttcagg aagctgagaa gcagtttatc cgagtcagtc tgcgagagga
    48421 gcttcaatta gatggacctg attctgaaag aaatcagcgg atttttcaag ctttacgata
    48481 ttttgatttg gagcaggcag tcgataagag tccctatcaa ttaagtggtg gtcagcaaaa
    48541 aatttttcag ctcctgacca tcttgaccag taaggcttcc gtgatcttgc tagatgaacc
    48601 ttttgcaggt ttggatgata gagcctgcca ttatttttgc aagtggattg tggaggagag
    48661 gaatcaagga agaagttttc tgctcattag tcatcgttta gaccctttga tttctgtggt
    48721 tgattattgg attgagatga ctagtcaggg tcttcggcat gtgaaagaag tgaccattac
    48781 caaaccactt acatctcaga gtagcaatac ccaaggggag gtgagatagt atggtcaaag
    48841 tagcaaccca gacaccgatt atcagtctct tcttgctgat tttatccttg gaaacatctt
    48901 tcattccttc gattgctctg aatctttcgg tagtcgcatt ttgtattctc tttatgctct
    48961 attaccgtcg atttaaaatg ttagcttgga tgatcatact tgccatttta ccatcttttg
    49021 ccaactactg ggcagttcag ttacacggag atgcttcaca ggcagtcatg cttggaacga
    49081 gggcctttgt gacagtttgt atcggccttg tctttgtttc ctctatttca ctaaaagagc
    49141 ttctcttgta cttggctcaa aaggggctat cacgctcttg gtcctatgcc ttgattgtgg
    49201 tattcaattc ttttcctctc attcagcaag aaatcaagtc cctcaaagaa gcttgcctat
    49261 tacgtggtca agaactacat ttttggtcgc ccttgattta cagtaaggtt ctgatgacag
    49321 tctttaggtg gcgccatctt tacctgagag ctctatctgc tcacggatat gacgaacatg
    49381 cacagttgaa gaatagctat cggacttttt atattcctaa aaaaacaaaa ttaatctacc
    49441 tgcttttctt tttattgctt caaaccagtc tatttttata aaggagttat tatggaattt
    49501 acagatattg cgatggaatt atccaagaaa gcttggcagg cttcctttca tcatcccttt
    49561 attttacaat tacaagaggg gaatttagaa cctgccattt tccgctatta cctgattcag
    49621 gatgcctact atctgaaggc cttctcagaa atctatcatc ttttggctga taagacttca
    49681 aaccaagaga tgaaaagact cttgaaacaa aatgctcagg gtttagtgga gggtgagtta
    49741 tttattcgcc aacaattttt caaggaattg gaaatcaacg accaggaaat ggagcaacat
    49801 ccaatcgctc caacctgtta tcattacatt tctcatattt ataggcaatt tgcagaaccg
    49861 aacttagcca tcgcttttgc aagcttgctt ccttgtcctt ggttatacca tgatataggc
    49921 aaatcactta atcttaaacc atcaccaaat cctctctatc aacaatggat tgaaacttat
    49981 attacggatg agttagagca acagatcaga gaggagggag cactggtcaa tcagctctat
    50041 cgagaaagtg acgagacaga caagcaaaaa atgctagatg ccttccacat cagtgttcat
    50101 atggaagcca agttttggga aatggcctac caacaccaga catggaagag cgatttacag
    50161 tctttagaaa aaggagaaga atagaagcat gagaaagcac caattacaag ttcacaaatt
    50221 aaccatttta tctatgatga ttgcccttga tgtagtcctt acacctatct ttcgaattga
    50281 gggaatggca ccgatgtcca gtgtagtcaa tattctagcg ggaatcatga tgggacctgt
    50341 ttatgccttg gctatggcta cagtcacagc ctttatccgt atgacgactc aagggattcc
    50401 gcctttagct ctcacaggag cgacttttgg agcccttctg gcaggtctct tttataagta
    50461 cggtcgaaaa tttcactatt ctgctctagg agagattttg ggaacaggta ttattggttc
    50521 cattgtttcc tatcctgtta tggtactctt tacaggatca gctgctaagc ttagctggtt
    50581 tatctacacg cctcgatttt tcggagcaac cttgattggt acagcgattt cctttattgc
    50641 ctttcgattt ttaatcaagc aggaattctt taaaaaagtg cagggatatt tctttagtga
    50701 aaggatagac tgatgcagga atttacaaat ccctttccta taggctctag ttccctcatt
    50761 cactgcatta ccaatgagat ttcttgtgag atgctggcaa atgggatttt ggctctggga
    50821 tgcaaacctg tcatggcaga tgattcccgt gaggttcttg attttactaa gcaaagtcag
    50881 gctcttttca tcaatttggg gcatttgtca gctgagaagg agaaagcaat ccgtatagca
    50941 gcttcttatg cagctcaagt ttgtctccca atggtagtag atgcggttgg cgtaacagct
    51001 tcatccattc gtaagagctt agtcagagac cttttagact atagacctac ggtccttaaa
    51061 ggaaacatgt cagaaattcg aagtcttgtt ggattaaagc atcacggcgt tggggtcgat
    51121 gcgagtgcta aagatcaaga aacggaggat ttgcttcaag tcttgaaaga ctggtgtcag
    51181 acctatcctg gtatgtcatt cttagttact ggccccaagg accttattgt ttcggagaat
    51241 caagttgctg tactggagaa tggctgtact gaattagact ggataacagg gacaggagac
    51301 ttggttggag ccttaacagc cgtttttctc agccaaggaa agactggttt tgaagcttct
    51361 tgcttagcag tctcttatct caatatcgct gctgagaaaa tagttgttca aggaatggga
    51421 ttggaagaat ttcgttacca agtactcaat cagctttcgc tcctaagaag agatgaaaat
    51481 tggctagata ccatcaaagg agaggtttat gaatagagaa gcacttagac tatatctggt
    51541 aaccaatcgc tatcaagatt ccgtggaaag ctttcttgca aaagttgaga cggcctgccg
    51601 ttcaggggtt accatagtcc aattgcgaga aaaaaatctc acaaccaatc aatattatca
    51661 actggcaaaa caagtcaagg aaataacaga tgcttatcag gtacccttga taatcgatga
    51721 tcggttggat gtttgtcttg cggttgatgc tgctggtctg catattggag atgacgaact
    51781 cccagtttcg gttgcccgac aagtcttggg tcctgaaaaa atcctcggtg tcaccgctaa
    51841 aacggttaaa agagctctgg aagcggagaa atcaggtgca gattacttgg ggacaggagc
    51901 catttttccg acaaccacca aggaaaatgc acccatcacc ctgatttcaa ccttgaaaac
    51961 aatttgccaa acggttgcca ttccaatagt tgctattggc ggcttgactt cggagaatat
    52021 tgatcagctt atgggcactg gcatagctgg tgtagctgtt gtacgtgatt tgatgcaagc
    52081 agaagatatt gaggcaaaaa cgcaagcctt tttaacaaag ttgcatgaca ttctttccta
    52141 attaatactc aatgaaaatc aaagagtaaa ctagaaagct agtcgcaggt tgctcaaagt
    52201 actgccttga ggttttagat aagactgacg aagtcagctc aaaacagtgt tttgaggttg
    52261 cagatggaag ctgacgtagt ttgaagagat tttcgaagag tataaaaact ctctaattcc
    52321 cttaaagtgg gaactagaga gttttttttc ttaatcttta aaagttgtat ggttgactgg
    52381 accagaacca tgaccgagtt gaggggcatc ttgaatagct tttgtgataa aggccttggc
    52441 cttatcaact gcctggtaaa gactcttgcc cttggctagt tcagcagtaa tcactgcagc
    52501 aaaggtacat ccagtaccat gggtgtgaca ggtttgaatt cgtgggcttt cccagacaaa
    52561 ttgttcattc ttggtaaaga ggaaatcttt agcaccacct ttgagatgtc cgcctttgat
    52621 aaccacagac tgaggaccaa attcttttaa aatcaggcga ccagcacgct gcatgtcttc
    52681 ggggtcatgg attgaaaaac caacaatctc ttctgcttca ggaagatttg gcgtaataat
    52741 agttgctaga ggtagtaagt ttgttttgag atagtctcta gcacttgagt caatcaaggc
    52801 atctccactt gtagcaacca taacaggatc aaggacatag ggacaatcca gttttttaag
    52861 atagggttgg atgatttcca tgatttcagt agtagccaac attccagttt ttacagcctg
    52921 aggtggaata tcagaaaaga cactgtccaa ttgggctttc aacatttgag gagaaacgtg
    52981 ctcgattagc tgaacacctc tggtattttg agcgacaaga ctggttacaa cagccattcc
    53041 atagacatct ctcgcttgga atgactttaa atctgccata atgccagcac caccactagg
    53101 gtcagtccct gcaatggtca aagcaacggg taaataagtc atctaaaacc tcccaaccaa
    53161 ctgaagtttg tattcttaag aacaagctag tctgttttag aaaggcaata gaagactgct
    53221 agtccccatt atcatttcca cttccatcag ctagcattac ctagattgag tcagagggat
    53281 ctaacagtcg ttaatctcag ctttacgcac ccctagtggt tgttttcttt tttctttagt
    53341 atagcatatt tttattgttt atatagtaat atttgactgc aaatcgtttt tcaaatgatt
    53401 aaaattctat ttttcgaaga aaatattatt tctataattg acaaatgtag attttgagag
    53461 tatactgatg agcgtaattg acaaatgtag attttggagg tatggtaatg cagatttcag
    53521 atgcagaatg gcaggtcatg aagattattt ggatgcaggg ggagcagacc agtacagatt
    53581 tgattagggt tttggcagag cggtttgatt ggtccaagtc cactgttcag acacttttgg
    53641 ctcggctggt tgagaaagag tgtttgactc ggaaaaaaga aggcaagttc tttgtttatt
    53701 cagccctttt aactctagac caaagtcggg atttacttgt ccaagatatc aaagacaagg
    53761 tttgttcccg taggattagg aatttgttgg ctgacttgat tgtagaatgt gaatttactc
    53821 agactgactt ggaagacttg gaagctgtga tttcagagaa gaaatcaagt gctgtaacag
    53881 aagtaagatg taattgtatg taaaggagac gtcatgttaa atagtattgt aaccattatt
    53941 tgtattgccc ttatcgcgtt tatcttgttt tggtttttca aaaagcctga aaaatctgga
    54001 caaaaagccc agcaaaaaaa cggataccaa gagatccgag tggaagtcat gggaggctat
    54061 actcctgagt tgattgtcct caagaaatca gtgccagccc gcattgtctt tgaccgcaag
    54121 gatccttcac catgtctgga tcaaattgtt tttccagatt ttggtgtaca tgcgaacctg
    54181 ccaatggggg aagagtatgt agtggaaatc acgcctgaac aggctggaga gtttggcttt
    54241 gcttgtggta tgaacatgat gcacggcaag atgattgtag agtaggtgga gactatgaca
    54301 gaaattgtga aagcaagctt agaaaatggc attcaaaaaa ttcgtatccg agctgaaaaa
    54361 ggctatcatc cagcccatat ccagcttcaa aagggaattc cagctgagat tacctttcat
    54421 cgtgctactc cttcaaactg ttataaggaa attctgtttg aagaagaagg tatcttggaa
    54481 ccaatcggcg tagatgagga gaaagtcatt cgttttacac ctcaagaatt agggcgacat
    54541 gaattttctt gtggcatgaa gatgcaaaag ggaagctata tagtcgttga gaagactcga
    54601 aaatctctat ctctcctgca acgtttttgg attactagta tctttactgt gcctcttgtg
    54661 attctcatga ttgggatgtt gacaggtagc attagtcatc aagtcatgca ttggggaacc
    54721 tttctagcaa caacgcctat tatgttagtt gcaggtaagc catatatcca gagtgcttgg
    54781 gccagtttta aaaagcacaa tgccaacatg gataccttgg ttgcgctggg aactctagtg
    54841 gcttatttct atagcctagt tgctctcttt gctggtctcc ctgtttactt cgaaagtgct
    54901 ggatttatcc tctttttcgt tcttttggga gcagtttttg agaaaaaaat gagaaaaaat
    54961 acgtcccaag ctgtggagaa attactggac ttgcaagcta aaaccgcaga agtcttgagt
    55021 gatgatagtt atgtccaagt tcctttggaa caagtcaagg taggcgacct gattcgagtg
    55081 catcccggtg aaaagattgc tgttgatggt gtcgtagtag aaggtgtctc tagtattgac
    55141 gaatccatgg tgacaggtga gagtctgcct gtggacaaga cagttggaga tactgtcatt
    55201 ggctcaacca tcaatcatag tggaacgctt gtctttagag cagaaaaagt tggctcagag
    55261 actgttttgg ctcagattgt ggattttgtg aagaaagctc agacaagtcg tgcgccgatt
    55321 caggacttga cggataagat ttcagggatt tttgtcccag tagttgtcat tttaggaatc
    55381 atgacctttt gggtttggtt cgtcttgctc agggatagtg tggtcgtgct tggagctagc
    55441 tttgtgtcct ctcttctcta cggagtggcg gttttgatta tcgcctgtcc ttgtgccttg
    55501 ggacttgcaa caccgacagc ccttatggtg gggacaggac gtagtgccaa gatgggggtt
    55561 ctcctcaaaa atggaactgt cttacaggaa atccagaaag ttcaaactct tgtctttgat
    55621 aagaccggga ctttgacgga agggaaacct gtggtaacag atatcatcgg cgacgaagta
    55681 gaagtgtttg gattggcagc ctccttggaa gatgcttctc aacacccact ggctgaggct
    55741 atcgttaagc gagcgagtga agctggactt gagtttcaaa ctgttgaaaa ttttcaggcc
    55801 ttgcacggga aaggtgtttc agggcgaatc aatggaaaac aagttttact tggaaatgct
    55861 aaaatgctgg atggcatgga tatttctaat acttatcaag ataaactaga agaactagaa
    55921 aaagaagcta agacagttgt gtttttagct gttgacaatg aaatcaaagg cttgcttgct
    55981 ttgcaagata ttcctaagga aaatgctaag ctagccatca gtcagctaaa aaaacgtggt
    56041 ctccgaacag tcatgctgac aggagacaat gctggtgtgg cgcgtgctat tgcagatcaa
    56101 atcggaattg aagaggtcat tgcaggcgtc ttgccagaag aaaaagccca tgaaatccat
    56161 aaactgcaac agtcagggaa agtagccttt gttggggacg gtatcaatga cgctcctgcc
    56221 cttagtgtag cagatgtggg gattgctatg ggagctggaa cagatatcgc catcgagtca
    56281 gcagatttgg tgttgacaac caataatctt ttaggagtgg ttcgtgcctt tgatatgagt
    56341 aagaaaacct ttcatcgaat tctactcaat cttttctggg cttttatcta caatgttgtc
    56401 ggaattccga ttgcagcagg agtcttttca ggtgttggac tggctctcaa cccagaattg
    56461 gcaggtctag ccatggcctt tagttctgta tctgttctga ccagttccct tctgttaaat
    56521 tttagtaaaa tagactaaaa gtaatgacta gatttctttg ttataaaaca gaaatgacag
    56581 aactttcaaa actgtattag aatagagaat agagagtttt gagcagattt ttagaaaagt
    56641 cagcataaat atgatacagt ggaatagtaa aaatttggag aacgtttcca attctatgta
    56701 atcgtattct ccaaatctaa aaaaattgaa ggagagttat cattatgact caagggaaaa
    56761 ttactgcatc tgcagcaatg cttaacgtat tgaaaacatg gggcgtagat acaatctacg
    56821 gtatcccatc aggaacactc agctcattga tggacgcttt ggctgaagac aaagatatcc
    56881 gcttcttaca agttcgccac gaagagacag gtgctcttgc agcggttatg caagctaaat
    56941 tcggcggctc aatcggggtt gcagttggtt caggtggtcc aggtgcgact cacttgatta
    57001 acggtgttta cgatgcagct atggataaca ctccattcct agcgatcctt ggatcacgtc
    57061 cagttaacga attgaacatg gatgctttcc aagagcttaa ccaaaaccca atgtacaacg
    57121 gtatcgctgt ttacaacaaa cgtgtagctt acgctgagca attgccaaaa gtaattgacg
    57181 aagcctgccg tgctgcaatt tctaaaaaag gtccagctgt tgttgaaatt ccagtaaact
    57241 tcggtttcca agaaatcgac gaaaactcat actacggttc aggttcatac gaacgctcat
    57301 tcatcgctcc tgctttgaac gaagttgaaa tcgacaaagc tgttgaaatc ttgaacaatg
    57361 ctgaacgccc agttatctat gctggatttg gtggtgttaa agctggtgaa gtgattactg
    57421 aattgtcacg taaaatcaaa gcaccaatca tcacaactgg taaaaacttt gaagctttcg
    57481 aatggaacta tgaaggtttg acaggttctg cttaccgtgt tggttggaaa ccagccaacg
    57541 aagtggtctt tgaagcagac acagttcttt tccttggttc aaacttccca tttgctgaag
    57601 tttacgaagc attcaagaac actgaaaaat tcatccaagt cgatatcgac ccttacaaac
    57661 ttggtaaacg tcatgccctt gacgcttcaa tccttggtga tgctggtcaa gcagctaaag
    57721 ctatccttga caaagtaaac ccagttgaat caactccatg gtggcgtgca aacgttaaga
    57781 acaaccaaaa ctggcgtgat tacatgaaca aactcgaagg taaaactgag ggtgaattgc
    57841 aattgtatca agtttacaat gcaatcaaca aacatgctga tcaagacgct atctactcaa
    57901 tcgacgtagg taacactact caaacatcta ctcgtcacct tcacatgaca cctaagaata
    57961 tgtggcgtac atctccgctc tttgcgacaa tgggtattgc ccttcctggt ggtatcgctg
    58021 ctaagaaaga caatccagat cgccaagtat ggaacatcat gggtgatgga gcattcaaca
    58081 tgtgctaccc agacgttatc acaaacgttc aatacgacct tccagttatc aaccttgtct
    58141 tctcaaatgc tgagtacggc ttcatcaaga acaaatacga agatacaaac aaacacttgt
    58201 ttggtgtaga cttcacaaac gctgactacg ctaaaattgc ggaagctcaa ggagctgttg
    58261 gattcacagt tgaccgtatc gaagacatcg atgcagttgt tgcagaagct gttaaattga
    58321 acaaagaagg taaaactgtt gtcatcgatg ctcgcatcac tcaacaccgt ccacttccag
    58381 tagaagtact tgaattggat ccaaaacttc actcagaaga agctatcaaa gccttcaagg
    58441 aaaaatacga agcagaagaa ctcgtaccat tccgtctctt cttggaagaa gaaggattgc
    58501 aatcacgcgc aattaaataa ttcctctcgc cgaaaatcaa atatgaaact tgtagacttt
    58561 attctttgat tttcatagag cagaacttta aaagatcgga gcaatccggt ctttttatgg
    58621 aggagagtaa atgaatttaa atcaattaga tattatcgtt tcaaatgttc cccaagtctg
    58681 tgctgacttg gagcatattt tggataaaaa ggcagattat gctgatgatg gttttgctca
    58741 gtttacgatt ggtagtcact gccttatgtt gtcacaaaat catttggttc ctttggaaaa
    58801 ctttcagtca ggaatcatta ttcatatcga ggttgaggat gtagaccaga actacaaacg
    58861 gttgaacgag cttggtataa aggttttaca cggaccaact gtaaccgatt ggggaacaga
    58921 gtccttatta gttcaaggac ctgctggtct agtgcttgat ttttatcgta tgaaataggt
    58981 cgcgtagtca tttgacgtta accttagcta tttttaaaat agaaattgag aatatgaact
    59041 attgaaagat cggagcaatc cggtcttttt atataaagaa attgcatata atactcatct
    59101 gctttcaaaa agcattctag tccatctccg attaacgatg gactttatca cctccttctc
    59161 cagtccttgt atgacatctt ggagttgatt catgacatct tccaaagttc gaaaggcttt
    59221 attcttaaat ccacgtttat gaatctcttt ccacacttgt tcgatgggtt catctctggt
    59281 gtgtatggag gaataaatgc aaaaccaata ttagtcggag tctttataag atttgcccgt
    59341 cagacgaaat agaatgattt gaaggcattt atgatattta gctgtacgag agtctttaaa
    59401 aagtgttttg atggtttgga tttcttcttt agttgatttc atatcactat tatataatgc
    59461 tttttgattt tagtatagta ttatcgtaga aaatggactc ggtgctatgg atacaccgga
    59521 tgagaatggt tatgtagcag atgactatcg gattacttac ttagaggccc acatcaaggc
    59581 catgcgagat gccatttaca aagacggggt tgacttgctt ggttatacga catggggctg
    59641 tatcgattcg gtttcagctg gcacagggga aatgaataag cgctatggct ttatctatgt
    59701 agatcgagat aatgtaggaa atgggactct caaacgtagc aagaagaagt ccttctattg
    59761 gtacatgtca tttatagcaa tggtgtaagc atcgagtaga gcacatttgt ttactatttt
    59821 tataaaatct tctccctgct ttataagatg taaaaaagag ttcaaatgga actctttttt
    59881 tgctataatg aggggagaaa aatcagacag gagattaaga tgtcagaacc attattttta
    59941 caatcagtta tgcaagaaaa aatctggggt ggtaccaagc tacgtgatga gtttggctac
    60001 gacatcccaa gtgaaaaagt cggagagtac tgggctatct cagctcatct aaatggtgtt
    60061 tctaaagttg ccaatggtcg ttacgaggga acagatcttg ctactttgta tgcggaacac
    60121 cgtgaattat ttggcaatcg tccagaacct gtatttccac ttttgaccaa gatcctcgat
    60181 gccaacgact ggctcagtgt ccaagttcac ccagacgatg cttatggact cgagcatgaa
    60241 ggcgaacttg gaaaaacaga atgttggtac atcattgcag cagatgaagg ttcagagatt
    60301 atctacggtc acaatgccaa gtcaaaagaa gaactccgcc agcaaatcga ggataagaac
    60361 tgggatgcgc tgttgacaaa agtgccagtt aaagcaggag atttcttcta tgtaccaagc
    60421 ggtaccatgc acgctatcgg ggcgggtatc ttgattcttg aaacccagca gtctagcgat
    60481 accacttacc gtgtctatga ctttgaccgt aaggatgaca agggcaattt acgtgaactt
    60541 catcttgaaa aatccatcga tgtcttgaac attggtgaac ccgcaaatag ccgtccagtg
    60601 acaatcaaag cagatgatct acgttccact ctccttgtat ccaatgattt cttcgcagtt
    60661 tacaaatggg aaattactgg aaaagttaac tttgaaaaga cagctgacta cagcttgttg
    60721 agtgtcttgg ctggtcaagg tcaactaact gttgacggga aaaactatcc aatccaaaaa
    60781 gggagacact ttatcctacc aagtgatgtt gaatcttgga ctctagaagg gcaagattta
    60841 gaattaattg ttagtcatcc ataaaaaaga aaggacctga gttcattact caagtccttt
    60901 tgattacata aattgggcga tgaagaccac gatgatgatt ggaatgacga aacgaagaag
    60961 gaagagccag acttggaaca gtccttgttt ccatgctctt tcatcgagat ggagttcctc
    61021 cattgcaaga gcctttttaa agatatagcc tgtaaaaagt gaaaggaaga gagctccaaa
    61081 tggcatgagg agattggaaa ccaagaagtc catagcgtca aagaaggctt taccaaaaat
    61141 gtgaacatcc gccatgacac cgtaagatag ggctgaagga atgccaaaga caaaggtcaa
    61201 aattcctaaa ataacactcc atttagcacg cttgctgttg tcctgattgg tgatattgtc
    61261 tacattgatt tccagcataa cgacagaaga agtgacagtc gcaaagagga agaggacata
    61321 gaaaatggtt ccaaaaggca tcttgtcaaa gagttgaggc aagacgataa agaccaagct
    61381 cggtccccct tcagactgga tattgaaggg ggaccgagct tggaaaatgg ctagacctgc
    61441 catgatggat accgagatat tcatggctac gatggagatt cttgactgga ccagattggt
    61501 tttcttgtcc aagtaagaag cataggtcaa catggctgta acccctagtg agagggcaaa
    61561 gaaagattgt ctcagagcat agaggagacc agcgctagtc agttttgaaa aatctggttt
    61621 gaggaagtaa agaacccctt ccatggcatt tggcaaactg agagagcgtt cgatgatgac
    61681 gacaaagatg ataaagagca ggggcatcat gactttcgaa gctctttcaa tccctttttg
    61741 aaccccacgt gatacaatga agatattcaa taggataaag gtcgcttgag ctcctagagc
    61801 aatggctgga tttgaaatga tcagacttcc tgcgaaacaa aatatggcat agtagttcta
    61861 tgaatgatga agcaagtaaa caactaactg atgcacgatt taagcgtctt gttggtgttc
    61921 agcgcacgac tttt
//
LOCUS       DAVDFK010000010        57665 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.10, whole genome shotgun sequence.
ACCESSION   DAVDFK010000010 DAVDFK010000000
VERSION     DAVDFK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.10"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            215..2197
                     /locus_tag="VUR04_000752"
     CDS             215..2197
                     /locus_tag="VUR04_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340681.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2498..7801
                     /locus_tag="VUR04_000753"
     CDS             2498..7801
                     /locus_tag="VUR04_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5340682.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGGDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVRTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKALKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQTGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LVLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGEQAT
                     YFDEIRTFENNSSMYEDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEENWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     IAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7968..10127)
                     /locus_tag="VUR04_000754"
     CDS             complement(7968..10127)
                     /locus_tag="VUR04_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET5340683.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10124..10720)
                     /gene="recU"
                     /locus_tag="VUR04_000755"
     CDS             complement(10124..10720)
                     /gene="recU"
                     /locus_tag="VUR04_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET5340684.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10786..11313
                     /locus_tag="VUR04_000756"
     CDS             10786..11313
                     /locus_tag="VUR04_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET5340685.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11383..11712
                     /gene="gpsB"
                     /locus_tag="VUR04_000757"
     CDS             11383..11712
                     /gene="gpsB"
                     /locus_tag="VUR04_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET5340686.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11733..12113
                     /gene="rnpB"
                     /locus_tag="VUR04_000758"
     ncRNA           11733..12113
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VUR04_000758"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12198..13355
                     /locus_tag="VUR04_000759"
     CDS             12198..13355
                     /locus_tag="VUR04_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET5340687.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13368..14762
                     /gene="mapZ"
                     /locus_tag="VUR04_000760"
     CDS             13368..14762
                     /gene="mapZ"
                     /locus_tag="VUR04_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET5340688.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVESGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     PASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14838..16262
                     /gene="gndA"
                     /locus_tag="VUR04_000761"
     CDS             14838..16262
                     /gene="gndA"
                     /locus_tag="VUR04_000761"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET5340689.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLNKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16274..16963
                     /locus_tag="VUR04_000762"
     CDS             16274..16963
                     /locus_tag="VUR04_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340690.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17062..17964
                     /locus_tag="VUR04_000763"
     CDS             17062..17964
                     /locus_tag="VUR04_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5340691.1"
                     /translation="MKLLKKMMPIALAVFFFGLLATSTVFADTMGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKKTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPATGIM
                     QTGWQFLGNRWYYLRSSGAMATGWYQDGSTWYYLDPSNGDMKIGWTKVNGNWYYLNSS
                     GAMVTGSQTIDGKVYNFASSGEWI"
     gene            17982..18857
                     /locus_tag="VUR04_000764"
     CDS             17982..18857
                     /locus_tag="VUR04_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5340692.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNNWYYLRSSGAMATGWYKDGSTWYYLNASNGDMKTGWFQVNGNWYYAYSSGALAVNT
                     TVDGYSVNYNGEWVR"
     gene            complement(18975..20207)
                     /locus_tag="VUR04_000765"
     CDS             complement(18975..20207)
                     /locus_tag="VUR04_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5340693.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGAVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(20250..21211)
                     /locus_tag="VUR04_000766"
                     /pseudo
     CDS             complement(20250..21211)
                     /locus_tag="VUR04_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            21739..22068
                     /locus_tag="VUR04_000767"
     CDS             21739..22068
                     /locus_tag="VUR04_000767"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5340694.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            22190..23068
                     /gene="mvk"
                     /locus_tag="VUR04_000768"
     CDS             22190..23068
                     /gene="mvk"
                     /locus_tag="VUR04_000768"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET5340695.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSYGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            23050..24003
                     /gene="mvaD"
                     /locus_tag="VUR04_000769"
     CDS             23050..24003
                     /gene="mvaD"
                     /locus_tag="VUR04_000769"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET5340696.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            23990..24997
                     /locus_tag="VUR04_000770"
     CDS             23990..24997
                     /locus_tag="VUR04_000770"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET5340697.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVRPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            24981..25991
                     /locus_tag="VUR04_000771"
     CDS             24981..25991
                     /locus_tag="VUR04_000771"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET5340698.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            26069..26767
                     /locus_tag="VUR04_000772"
     CDS             26069..26767
                     /locus_tag="VUR04_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET5340699.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            26764..27759
                     /locus_tag="VUR04_000773"
     CDS             26764..27759
                     /locus_tag="VUR04_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5340700.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLVLFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            27773..28405
                     /locus_tag="VUR04_000774"
     CDS             27773..28405
                     /locus_tag="VUR04_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5340701.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            28406..28648
                     /locus_tag="VUR04_000775"
     CDS             28406..28648
                     /locus_tag="VUR04_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET5340702.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            28573..28884
                     /locus_tag="VUR04_000776"
     CDS             28573..28884
                     /locus_tag="VUR04_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET5340703.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            28909..29175
                     /locus_tag="VUR04_000777"
                     /pseudo
     CDS             28909..29175
                     /locus_tag="VUR04_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            29325..29564
                     /locus_tag="VUR04_000778"
     CDS             29325..29564
                     /locus_tag="VUR04_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340704.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            29609..30242
                     /locus_tag="VUR04_000779"
                     /pseudo
     CDS             29609..30242
                     /locus_tag="VUR04_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
     gene            30541..30933
                     /locus_tag="VUR04_000780"
     CDS             30541..30933
                     /locus_tag="VUR04_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5340705.1"
                     /translation="MDSPKSLASYRVIGIIDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            31094..32377
                     /locus_tag="VUR04_000781"
     CDS             31094..32377
                     /locus_tag="VUR04_000781"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET5340706.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(32425..34791)
                     /locus_tag="VUR04_000782"
     CDS             complement(32425..34791)
                     /locus_tag="VUR04_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET5340707.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDAYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQTCMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(35070..35684)
                     /gene="lepB"
                     /locus_tag="VUR04_000783"
     CDS             complement(35070..35684)
                     /gene="lepB"
                     /locus_tag="VUR04_000783"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET5340708.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            complement(35696..36568)
                     /locus_tag="VUR04_000784"
     CDS             complement(35696..36568)
                     /locus_tag="VUR04_000784"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET5340709.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SIKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            36655..36957
                     /gene="zapA"
                     /locus_tag="VUR04_000785"
     CDS             36655..36957
                     /gene="zapA"
                     /locus_tag="VUR04_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET5340710.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            36954..37502
                     /locus_tag="VUR04_000786"
     CDS             36954..37502
                     /locus_tag="VUR04_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET5340711.1"
                     /translation="MISLLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            37606..39942
                     /locus_tag="VUR04_000787"
     CDS             37606..39942
                     /locus_tag="VUR04_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET5340712.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESRVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETACVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     regulatory      40106..40194
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            40285..41607
                     /locus_tag="VUR04_000788"
     CDS             40285..41607
                     /locus_tag="VUR04_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET5340713.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALMVLSPVVIAETKKYFDK"
     gene            41825..42373
                     /locus_tag="VUR04_000789"
     CDS             41825..42373
                     /locus_tag="VUR04_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET5340714.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            42483..43382
                     /locus_tag="VUR04_000790"
     CDS             42483..43382
                     /locus_tag="VUR04_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET5340715.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILNLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(43407..44681)
                     /gene="serS"
                     /locus_tag="VUR04_000791"
     CDS             complement(43407..44681)
                     /gene="serS"
                     /locus_tag="VUR04_000791"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET5340716.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNAEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILEIYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(44895..45266)
                     /locus_tag="VUR04_000792"
     CDS             complement(44895..45266)
                     /locus_tag="VUR04_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET5340717.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(45269..46633)
                     /locus_tag="VUR04_000793"
     CDS             complement(45269..46633)
                     /locus_tag="VUR04_000793"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET5340718.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            46958..47743
                     /locus_tag="VUR04_000794"
     CDS             46958..47743
                     /locus_tag="VUR04_000794"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET5340719.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            47837..48271
                     /locus_tag="VUR04_000795"
     CDS             47837..48271
                     /locus_tag="VUR04_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5340720.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            48271..49245
                     /locus_tag="VUR04_000796"
     CDS             48271..49245
                     /locus_tag="VUR04_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET5340721.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            49305..49529
                     /locus_tag="VUR04_000797"
     CDS             49305..49529
                     /locus_tag="VUR04_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET5340722.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            49648..50622
                     /gene="fabK"
                     /locus_tag="VUR04_000798"
     CDS             49648..50622
                     /gene="fabK"
                     /locus_tag="VUR04_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET5340723.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            50615..51535
                     /gene="fabD"
                     /locus_tag="VUR04_000799"
     CDS             50615..51535
                     /gene="fabD"
                     /locus_tag="VUR04_000799"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET5340724.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            51569..52300
                     /gene="fabG"
                     /locus_tag="VUR04_000800"
     CDS             51569..52300
                     /gene="fabG"
                     /locus_tag="VUR04_000800"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET5340725.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            52322..53557
                     /gene="fabF"
                     /locus_tag="VUR04_000801"
     CDS             52322..53557
                     /gene="fabF"
                     /locus_tag="VUR04_000801"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET5340726.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            53560..54045
                     /locus_tag="VUR04_000802"
     CDS             53560..54045
                     /locus_tag="VUR04_000802"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET5340727.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            54042..54464
                     /gene="fabZ"
                     /locus_tag="VUR04_000803"
     CDS             54042..54464
                     /gene="fabZ"
                     /locus_tag="VUR04_000803"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET5340728.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            54476..55843
                     /gene="accC"
                     /locus_tag="VUR04_000804"
     CDS             54476..55843
                     /gene="accC"
                     /locus_tag="VUR04_000804"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET5340729.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            55880..56746
                     /locus_tag="VUR04_000805"
     CDS             55880..56746
                     /locus_tag="VUR04_000805"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET5340730.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            56743..57510
                     /locus_tag="VUR04_000806"
     CDS             56743..57510
                     /locus_tag="VUR04_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET5340731.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
BASE COUNT        17170 a        10698 c        13167 g        16630 t
ORIGIN      
        1 taggctccat aatatccata gggaatttac ccactacaaa tattatagag ccaaaattcc
       61 ttgactatgt gatatagttg agggattttt aaatgatatt catatttttt gcaaagatgt
      121 tgtttgaaaa ataattttca aaaattctga aaattctgtt gacatctttc tgaaaagagt
      181 ctataatgga gagaaagttt taaaggagaa aatgatgaaa agttcaaaac tatttgccct
      241 tgcgggcgtg acattattgg cggcgactac tttagctgca tgctctggat caggttcaag
      301 cactaaaggt gagaagacat tctcatacat ttatgaaaca gaccctgata acctcaacta
      361 tttgacaact gctaaggctg cgacagcaaa tattaccagt aacgtggttg atggtttgct
      421 agaaaatgat cgctacggga actttgtgcc gtctatggct gaggattggt ctgtatccaa
      481 ggatggattg acttacactt atactatccg taaggatgca aaatggtata cttctgaagg
      541 tgaagaatac gcggcagtca aagctcaaga ctttgtaaca ggactaaaat atgctgctga
      601 taaaaaatca gatgctcttt accttgttca agaatcaatc aaagggttgg atgcctatgt
      661 aaaaggggaa atcaaagatt tctcacaagt aggaattaag gctctggatg atcagacagt
      721 tcagtacact ttgaacaaac cagaaagctt ctggaattct aagacaacca tgggtgtgct
      781 tgcgccagtt aatgaagagt ttttgaattc aaaaggggat gattttgcca aagctacgga
      841 tccaagtagt ctcttgtata acggtcctta tttgttgaaa tccattgtga ccaaatcttc
      901 tgttgaattt gcgaaaaatc cgaactactg ggataaggac aatgtgcata ttgacaaagt
      961 taaattgtca ttctgggatg gtcaagatac cagcaaacct gcagaaaact ttaaagatgg
     1021 tagccttaca gcagctcgtc tctatccaac aagtgcaagt ttcgcagagc ttgagaagag
     1081 tatgaaggac aatattgtct atactcaaca agactctatt acgtatctag ttggtacaaa
     1141 tattgaccgt cagtcctata aatacacatc taagaccagc gacgaacaaa aggcatcgac
     1201 taaaaaggct ctcttaaaca aggatttccg tcaggctatt gcatttggat ttgaccgtac
     1261 agcctatgcc tctcagttga atggacaaac tggagcaagt aaaatcttgc gtaatctctt
     1321 tgtgccacca acatttgttc aagcagatgg taaaaacttt ggcgatatgg tcaaagagaa
     1381 attggtcact tatggggatg aatggaagga tgttaatctt gcagattctc aggatggtct
     1441 ttacaatcca gaaaaagcca aggctgaatt tgctaaagct aaatcagcct tacaagcaga
     1501 aggtgtgaca ttcccaattc atttggatat gccagttgac caaacagcaa ctacaaaagt
     1561 tcagcgcgtc caatctatga aacaatcctt ggaagcaact ttaggagctg ataatgtcat
     1621 tattgatatt caacaactac aaaaagacga agtaaacaat attacatatt ttgctgaaaa
     1681 tgctgctggc gaagactggg atttatcaga taatgtcggt tggggtccag actttgccga
     1741 tccatcaact taccttgata tcatcaaacc atctgtagga gaaagtacta aaacatattt
     1801 agggtttgac tcaggggaag ataatgtagc tgctaaaaaa gtaggtctat atgactacga
     1861 aaaattggtt actgaggctg gtgatgaggc tacagatgtt gctaaacgct atgataaata
     1921 cgctgcagcc caagcttggt tgacagatag tgctttgatt attccaacta catctcgtac
     1981 agggcgtcca atcttgtcta agatggtacc atttacaata ccatttgcat tgtcaggaaa
     2041 taaaggtaca agtgaaccaa tcttatataa atacttggaa cttcaagaca aggcagtcac
     2101 tgtagatgaa taccaaaaag ctcaggaaaa atggatgaaa gaaaaagaag agtctaataa
     2161 aaaggctcaa gaagatctcg caaaacatgt gaaataactg ttgcaaaata taagaaagga
     2221 tttagtattt ctcttgaatg ctgaatcctt ttttacattt gtaaagaaag attctaaatg
     2281 tactgacccc caaaagttgg agcctctttt tgtcagaata gagaaaattt ttgttaattt
     2341 tacttgtttc ctattgcttt ctcagctatt atttgttata ttaaaagtat aattattttt
     2401 tatttatcag ggttaagcat tgcactttca gaggaaggag tattttttaa aaaggaaatg
     2461 taaacgcttg ctcaaaaatg aaaggattta gaagtttatg aataaaggat tatttgaaaa
     2521 acgttgtaaa tatagtattc ggaaattttc attaggtgtt gcttctgtta tgattggagc
     2581 tgcattcttt gggacaagtc cggttcttgc agatagcgtg cagtctggtt ccacggcgaa
     2641 tttaccagct gatttagcta ctgctcttgc aacagcaaaa gagaatgatg ggcgtgattt
     2701 tgaagcgcct aaggtgggag gagaccaagg ttctccagaa gttacagatg gacctaagac
     2761 agaagaagaa ctattagcac ttgaaaaaga aaaaccggct gaagaaaaac caaaagagga
     2821 taaacctgca gctgctaaac ctgaaacacc taagacggta acccctgaat ggcaaacggt
     2881 agagaaaaaa gaacaacagg gaacagtcac tatccgagaa gaaaaaggtg tccgctacaa
     2941 ccaactatcc tcaactgctc aaaatgataa cgcaggtaaa ccagccctgt ttgaaaagaa
     3001 gggcttgacc gttgatgcca atggaaatgc aactgttgat ttaaccttca aagatgattc
     3061 tgaaaagggc aaatcacgct ttggtgtctt cttgaaattt aaagatacca agaataatgt
     3121 ttttgtcggt tatgacaagg atggctggtt ctgggaatac aaaactccag gtaatagcac
     3181 atggtataaa ggcaaccgtg ttgctgctcc tgaaacagga tcaacaaacc gtctctctat
     3241 cactctcaag tcagacggtc agctaaatgc cagcaataac gatgtcaatc tctttgacac
     3301 agtgactcta ccagctgcgg tcaatgacca tcttaaaaat gagaagaaga ttcttctcaa
     3361 ggcgggctct tatgacgatg agcgaacagt tgttagcgtt agaacagata accaagaggg
     3421 ggtaaaaaca gaggataccc ctgctgaaaa agaaacaggt cctgaagttg atgatagcaa
     3481 ggtgacttat gacacgattc agtctaaggc cctcaaagca gtgattgacc aagccttccc
     3541 tcgtgtcaag gaatacagct tgaatggaca tactttgcca ggacaggtgc aacagttcaa
     3601 ccaagtcttt atcaataacc accgaatcac ccctgaagtc acttataaga aaatcaatga
     3661 gacaacagca gagtacttga tgaagattcg cgatgatgct cacttaatca atgcggaaat
     3721 gacagtacgc ttgcaagttg tggacaatca attgcatttt gatgtgacca agattgtcaa
     3781 ccacaatcaa gtcactccag gtcaaaagat tgatgacgaa agaaaactac tttcttctat
     3841 tagtttcctc ggcaatgctt tagtctctgt ttctagtgat caaactggtg ctaagtttga
     3901 tggggcaacc atgtcaaaca atacacatgt cagcggagat gatcatatcg atgtaaccaa
     3961 tccaatgaag gatttggcta agggttacat gtatggattt gtttctacag ataagcttgc
     4021 tgctggtgtt tggagtaact ctcaaaacag ctatggtggt ggttcgaatg actggactcg
     4081 tttgacagct tataaagaaa cagtcggaaa tgccaactat gtaggaatcc acagctctga
     4141 atggcaatgg gaaaaagctt ataagggcat tgttttccca gaatacacga aggaacttcc
     4201 aagtgctaag gttgttatca ctgaagatgc caatgcagac aagaaagttg attggcaaga
     4261 tggtgccatt gcttatcgta gcattatgaa caaccctcaa ggttgggaaa aagttaagga
     4321 tatcacagct taccgtatcg cgatgaactt tggttctcaa gcacaaaatc cattccttat
     4381 gaccttggat ggtatcaaga aaatcaatct ccacacagat ggtcttgggc aaggtgttct
     4441 ccttaaagga tatggtagcg aaggccatga ctctggtcac ttgaactatg ctgatattgg
     4501 taagcgtatc ggtggtgtcg aagacttcaa gaccctaatt gagaaggcta agaaatatgg
     4561 agctcatcta ggtatccacg ttaacgcttc agaaacttat cctgagtcta aatacttcaa
     4621 tgaaaaaatt ctccgtaaga atccagatgg aagctatagc tatggttgga actggctaga
     4681 tcaaggtatc aacattgatg ctgcctatga cctagctcat ggtcgtttgg cacgttggga
     4741 agatttgaag aaaaaacttg gtgacggtct cgactttatc tatgtggacg tttggggtaa
     4801 tggtcaatca ggtgataacg gtgcctgggc tacccacgtt cttgctaaag aaattaacaa
     4861 acaaggctgg cgctttgcga tcgagtgggg ccatggtggt gagtacgact ctaccttcca
     4921 tcactgggca gctgacttga cctacggtgg ctacaccaat aaaggtatca acagtgccat
     4981 cacccgcttt atccgtaacc accaaaaaga tgcttgggtt ggggactaca gaagttatgg
     5041 tggtgcagcc aactatccac tgctaggtgg ctacagcatg aaagactttg aaggctggca
     5101 aggaagaagt gactacaatg gctatgtaac caacttattt gcccatgacg tcatgactaa
     5161 gtacttccaa cacttcactg taagtaaatg ggaaaatggt acaccggtga ctatgaccga
     5221 taacggtagc acctataaat ggactccaga aatgcgagtg gaattggtag atgctgacaa
     5281 taataaagta gttgtaactc gtaagtcaaa tgatgtcaat agtccacaat atcgcgaacg
     5341 tacagtaact ctcaacggac gtgtcatcca agatggttca gcttacttga ctccttggaa
     5401 ctgggatgca aatggtaaga aactttctac tgataaggaa aagatgtact acttcaatac
     5461 gcagactggt gcaacaactt ggacccttcc aagtgattgg gcaaagagca aggtttacct
     5521 ttacaagcta actgaccaag gtaagacaga agagcaagaa ctaactgtaa aagatggtaa
     5581 aattacccta gttcttctag caaatcaacc atacgttctc tatcgttcga aacaaaccaa
     5641 tcctgaaatg tcatggagcg aaggcatgca catctatgac caaggattta acagtggaac
     5701 cttgaaacac tggaccattt ctggtgatgc ttctaaggca gaaattgtca agtctcaagg
     5761 ggcaaacgat atgcttcgta ttcaaggaaa caaagaaaaa gttagtctca ctcagaaatt
     5821 aactggcttg aaaccaaata ccaagtatgc cgtttatgtc ggtgtcgata accgtagtaa
     5881 tgctaaggcg agcatcactg taaatactgg tgaaaaagaa gtgactactt ataccaataa
     5941 gtctctcgcg ctcaactatg ttaaggccta cgcccacaat acacgtcgtg acaatgctac
     6001 agttgacgat acaagttatt tccaaaacat gtatgccttc tttacaactg gatcggacgt
     6061 ctcaaatgta actctgacat tgagtcgtga agctggtgaa caagcaactt actttgatga
     6121 aattcgtacc tttgaaaaca attcaagcat gtacgaagac aagcatgata caggtaaagg
     6181 cacctttaag caagactttg aaaatgttgc tcagggtatc ttcccatttg tagtgggtgg
     6241 tgtcgaaggt gtcgaagaca accgcactca cttgtctgaa aaacacgatc catatacaca
     6301 acgtggttgg aatggtaaga aagtcgatga tgttatcgaa gaaaattggt cactcaagac
     6361 aaatggacta gtgagccgtc gtaacttggt ttaccaaact attccgcaaa acttccgttt
     6421 tgaagcaggt aagacctacc gtgtaacctt tgaatacgaa gcaggttcag acaataccta
     6481 tgcttttgta gtcggtaagg gagaattcca gtcaggtcgt cgtggcactc aagcaagcaa
     6541 cttggaaatg catgaattgc caaatacttg gacagattct aagaaagcca agaaggcaac
     6601 cttccttgtg acaggtgcag aaacagggga tacttgggta ggtatctact caactggcaa
     6661 tgcaagtaat actcgtggtg attctggtgg aaatgccaac ttccgtggtt ataacgactt
     6721 catgatggat aatcttcaaa tcgaagaaat taccctaaca ggtaagatgt tgacagaaaa
     6781 tgctctgaag aactacttgc caacgattgc catgactaac tacaccaaag agtctatgga
     6841 tgctttgaaa gaggcggtct ttaacctcag tcaggccgat gatgatatca gtgtggaaga
     6901 agcgcgtgca gagattgcca agattgaagc cttgaagaat gctttggttc agaagaaaac
     6961 ggctttggta gcagatgact ttgcaagtct tacagctcct gctcaggctc aagaaggtct
     7021 tgcaaatgcc tttgatggaa acttatctag tttatggcat acatcatggg gcggaggaga
     7081 tgtaggcaag cctgcaacca tggtcttgaa agaaccaact gaaatcactg gacttcgtta
     7141 tgttccacgt ggatcaggtt caaatggtaa cttgcgtgat gtgaaacttg ttgtgacaga
     7201 tgagtctggc aaggagcata cctttactgc aactgattgg ccagataaca ataagccaaa
     7261 agacattgat tttggtaaga caattaaggc taagaaaatt gtccttacag gtactaagac
     7321 ttacggagat ggtggcgata aataccaatc tgcagcggaa ctcatcttta ctcgtccaca
     7381 ggtagcagaa acacctcttg acttgtcagg ctatgaagca gctttggcta aggctcagaa
     7441 attaacagac aaagacaatc aagaggaagt agctagcgtt caggcaagca tgaaatatgc
     7501 gacggataac catctcttga cggaaagaat ggtggaatac tttgcagatt atctcaacca
     7561 attaaaagat tctgctacga aaccagatgc tccaactgta gagaaacctg agtttaaact
     7621 tagctcttta gcttccgagc aaggtaagac gccagattat aagcaagaaa tagctagacc
     7681 agaaacacct gaacaaatct tgccagcaac aggtgagagt caatctgaca cagccctctt
     7741 cctagcaggt gttagcctag ccctatctgc tctctttgta gtaaaaacga agaaagacta
     7801 gtatttagta aaacctctta acaagattac ggaagcagtc tctatctttt ccaatgaggt
     7861 ttatagtaca gaaaaagcct gagaagatgt cttctcaggc ttttgttaag cacataaata
     7921 caatagtgct atgacaaaat cacccagaaa aatctgggtg ataaatgtta tggttgtgct
     7981 ggttgaggat tctgattttg ttgatcaggg gttgtatttg attgttgcgt attgttgtta
     8041 ggattggtag tcgtactatt atttgtgctt ggagtggttg agctagactg tgaagttgaa
     8101 ctatctgatg atgagcttga actttcagtt gatgggggtt gttgtggagc aggtgagttc
     8161 cacgtagaac gagcaccatt tttaaatacg aattctccat ttctgtagag cccctctggt
     8221 atattccaat cctctggatt gcttccttca gacaggtagg tcatcataga gcggtaaact
     8281 ttggcagcga ccgtaaggcc attgcctaca agtggtgtca gacggttaga atagcctgtc
     8341 catacagcca ttgaatattt acgcgtatag ccagcaaata gttcgtcagg tgctacaaat
     8401 tgagaggtct tgatgtggtt ttcaatttcc tcgtctgtat agttagaggt tcctgtttta
     8461 ccagcctgag ggagccaagc aagataggca tttcgtccag ttccataact caagactgtt
     8521 ttcatcatgt cggtcatcat ataggctgtc gtttccttca tggcacgagt tccgacatta
     8581 gagaactctt tttcactccc atcactaaag acgactttat ggatatacat tggtttatag
     8641 taagttccac catttgcaaa ggcagcgtaa gcagcagcca tcttttcact acttgctcca
     8701 tattttttgt ctgattcggt tgtgttactt gaaatggcat ttgagtagtg aatacttggg
     8761 tagtcgattc ctagaccatt taggaaagtc ttggcgcggt tgagtccgac cttgtttaga
     8821 gtttccacgg ctgggacgtt tcgcgattgt tgcagggcgt attgcaaggt gatgttgcca
     8881 aagtagcccc tatcccagtt ataaacagga gtatttgtcc cagggtagtt atagggctca
     8941 tcgtgaacga tagtagcagt tgaatcgtag acaccgtact ccaaggcagg agcatagtct
     9001 gtgatcggtt tcatagttga tccccagtcg cggtttgttt ctactgcttg gttaattccg
     9061 aaggaaacat tacttgactg atggcgtgct cctagctggg caatgacttt accgttagaa
     9121 acatcaacaa tggtagaagc gacttgcaat tcatcgtctg gataggcaac gtattcgtct
     9181 gtattgtaaa tatcccacag atgtttttga gcttcttggt ctacatttgt gtagacatcc
     9241 atcccagttg tgagcaggtt atagcctgtt tcttcttcaa cttgattgat gacttccttg
     9301 aggtaattat ccatgtaagc agggtaatta cttgctgatt tgagactttg tagtccatca
     9361 gtaattggtg tattgactgc tttctcatac tgttcagcag agatgtagcc ttgatttttc
     9421 atttcagata agaccaagtt tcggcggtct tgggctgctt ctggatgtga ataggggtca
     9481 tattggtttg gtgcctgagg cattccagcc agcaaggcta actgaggtaa acttaaatta
     9541 ttgaggtctt taccatagta gttttgagct gctgtctgca ttccatagtt cccattagac
     9601 atgtagacct tatttatata gtaggtcaag atttcttgct tggttgcttt ttgttctaac
     9661 tgaatcgcta accaagcttc ctgagcctta cgagaaatag tctggtcgga agtcgaagtt
     9721 gaaaagtaag tcaacttaat caactgttga gtgagagttg atccaccttg gagggaattg
     9781 ctttgcagat tgcgcaagaa agctcccagg atacggatgg tatcaatccc cctgtggtcg
     9841 aagaagcgat ggtcttcgat agaaacgatt gccttaacca aatctgtggg aatatcatta
     9901 gcttgggcat tgacgcggcg ttcagaaccc aagtcagcaa tgagttgatt tttattgtcg
     9961 tagattttac tagaagttgt tgcaactagt ttactctcgg ataggctagg agccttgcta
    10021 acgtagtaga aaaaaactcc tccgcctaag acaatggctg cgataaccaa gcttaagaag
    10081 ctaatgctca gatacttgat taggcgcaga atcgttggtt tgttcatctt gttttaccac
    10141 ctaataaatg ttctttgata acattgagat aaggaatttg agggaaggca ccagccttga
    10201 tttcatatcc atattctcga atatattcaa gtggcattga tttttgtccc ttatcttgat
    10261 gatagaagcg aatcaaatcg aatgccggca ataagtaggt ttcttgctga gaagaaaagt
    10321 gaagaaggac aaagcagatt ccttgttggg caaggacttg ttccatatgc tgaatctgat
    10381 gtggatgaaa atttttcatc ggaatcgcac gtttttgttt tgtttccttg acttcaaagt
    10441 cgatgtaata tccattataa acgccagaat agtccgtcgt tgaagcttgt cgaaaatagg
    10501 cttcaacaat cttggcacga cttcgttgtg gatagtccac ttgtacgatt tgaataggag
    10561 ttggtttctt atgtataaca gccaagccct gagacaaata gtagtcgttg gtagcattga
    10621 tcatcttttc aaaagacatt cctcgatttg cgaaattttt gggttgagaa agagatgttt
    10681 gtcttttttg tgatgaaact ttatgtggat agttgaccat aattctcctt attggtacaa
    10741 taacatcact ttattatacc ataatttgca cagaaagggt taaaaatggc tacagctttg
    10801 gttttaggct attctgcttt tgatttgggt ttattttctg ataaggatcc tcgtcttaaa
    10861 ttgattaaaa aagcgatacg taaagattta gaggctatgg cagcagatgg ggtgtcttgg
    10921 cttgtgttta cagggagttt gggttttgaa tattgggttt tagaggttgc tcaggagatg
    10981 aaaaccgaat acggtttcca gttggccacc atttttgctt ttgaaaccca tggggaaaat
    11041 tggaatgaag gcaatcagat gaaactgagt cgctttaagc aggtagactt tgtcaaatat
    11101 gcctatcctc gctatgaaca caaggggcag ttaagagatt atcagcagtt tttgctggaa
    11161 aacacgacta gttcctatct tttttatgat gaagaaaatg aaacaaaact agcttatttt
    11221 taccaaaaga tgaaaaatca agaggactat tttataaaga gattaacatt tgatcaatta
    11281 aatgaacttg ctgaaaattt ttccgaaaat tgaagctttg accttgattt ttgtttgcct
    11341 ttttttatat aataatacta gcaagcgaga atggagagag acatggcaag tattattttt
    11401 tcagcgaaag atatttttga acaagagttt ggacgtgaag tccgtggcta taataaagta
    11461 gaagttgacg agtttttaga cgatgtcatc aaggactatg aaacctatgc tgccttggtc
    11521 aagtcacttc gtcaggaaat tgcggatttg aaggaagaat taactcgtaa accgaaacct
    11581 tcaccagttc aagcagaacc ccttgaagcg gcaattacaa gttctatgac gaattttgat
    11641 attttgaaac gcctgaatag attggaaaaa gaagtttttg gtaaacaaat tttagataac
    11701 tcagattttt aagtagttat ttgagatgtg caatttttgg ataatcgcgt gaggagaatt
    11761 gcttctcatg aggaaagtcc atgctagcac aggctgtgat gcctgtagtg tttgtgctag
    11821 gcgaaaccat aagcctaggg acgagaaatc gttacggcag ttgaaatggc taagtccttg
    11881 gataggccag agtaggcttg aaagtgccac agtgacgaag tctttctgga aacagagaga
    11941 gtggaacgcg gtaaacccct caagctagca acccaaattt tggtcggggc atggagtacg
    12001 cggaaacgaa cgtagtattc tgactgctat cagctagagc tgttagtggt agacagatga
    12061 ttatcgaagg aagtggtcct agtcacttct ggaacaaaac atggcttata gaaaattgca
    12121 tataggttgg ggctgagaaa ttttctcaac ctcatttttt aaagtggaca tatagaaagg
    12181 tcttgcaaga ctgtaacatg aaaaaagaat ttaatttaat tgcaactgtg gcagcagggc
    12241 ttgaggctgt cgttggtcgt gaagtgcgag agttgggcta cgattgccag gttgaaaatg
    12301 gacgtgttcg ttttcaagga gacgtgagag ctattatcga aaccaacctt tggcttcggg
    12361 cagcagatcg tatcaaaatt atcgtaggaa cgttcccagc taagactttt gaagagctat
    12421 ttcagggagt tttcgcttta gattgggaaa attatttacc acttggagct cggttcccga
    12481 tttcaaaagc taaatgtgtt aagtccaaac ttcacaatga gcccagtgtt caggctattt
    12541 ctaagaaagc tgttgtcaag aaattgcaga aacactatgc tcgcccagaa ggggttcctc
    12601 tgatggagaa tggcccagag tttaagattg aggtctctat tctcaaagat gtggcaactg
    12661 tcatgattga tacgaccggg tctagcctct ttaaacgtgg ttatcgtacc gaaaaaggtg
    12721 gcgctcctat caaggaaaat atggcagcag ccattttaca actttctaac tggtatccag
    12781 acaagccttt gattgatccg acctgtggtt cggggacttt ctgtattgag gcagttatga
    12841 ttgctagaaa gatggcgcca ggtcttcgtc gctcttttgc atttgaggaa tggaactgga
    12901 tcagcgatcg cttgattcaa gaagtgcgca cagaagcggc taaaaaagta gaccgtgagc
    12961 ttgagctgga tatcatgggc tgtgatattg atgctcgcat ggtggaaatt gctaaggcca
    13021 atgctcaggc agctggtgtt gcaggagaca ttacttttaa gcagatgcgc gtgcaggatt
    13081 tacgttccga taaaatcaat ggagtaataa tttccaatcc gccttatggt gaacgtttgt
    13141 cagatgatgc aggggtgacc aagctctatg ctgagatggg gcaagtattt gcaccgctga
    13201 aaacttggag caaatttatc ctgactagtg atgaagcttt tgaaagcaag tatggtagcc
    13261 aagcagataa gaagcgtaag ttatacaacg gaaccttgaa agtggatctg tatcaatatt
    13321 ttggtcagcg tgtcaaacgg caagaggtaa aatagaaagg gatactcatg agtaaaaaaa
    13381 gacgaaatcg tcaaaaaaaa gaaggtcaag aaccgcaatt tgattttgat gaagcaaaag
    13441 agctaacagt tggtcaagct attcgtaaaa atgaagaagt ggaatcagga gtcttgcctg
    13501 aggattccat tttggacaag tatgttaagc aacacagaga tgaaattgag gcggataagt
    13561 ttgcgactcg tcaatacaaa aaagaggagt tcgttgaaac tcagagtctg gatgatttaa
    13621 ttcaagagat gcgtgaggct gtagagaagt cagaagcttc ttcggaggaa gttccatctt
    13681 ctgaagacat cttactaccc ttgcctctgg acgatgagga gcaaggcttg gatcctctat
    13741 tgctagatga tgaaaatcca acagaaatga ctgaagaagt ggaagaggag caaaaccttt
    13801 ctcgtctgga tcaagaggac tcagaaaaga aaagtaaaaa aggctttatt ttgaccgttt
    13861 tggcgcttgt atcagtaatt atttgtgtca gtgcttatta tgtctaccgt caagtggctc
    13921 gttcgactaa ggaaattgaa acttctcaat caactacagc caatcaatcg gatgtggatg
    13981 attttaatac actttatgac gccttttaca cagatagcaa taaaacggct ttgaaaaata
    14041 gccagtttga taaactgagt caactcaaga ctttacttga taagctggaa ggtagtcgtg
    14101 aacatacgct tgccaaatct aaatatgata gtctagcaac gcaaatcaag gctattcaag
    14161 atgtcaatgc tcaatttgag aaaccagcta ttgtggatgg tgtgttggat accaatgcca
    14221 aagccaaatc ggatgctaaa tttacggata ttaaaactgg aaatacggag cttgataaag
    14281 tgctagataa ggctatcagt cttggtaaga gccagcaaac aagtacttcc agctcaagtt
    14341 caagtcaaac tagcagctca agctctagtc cagcaagttc aaatacgact agtgagccaa
    14401 aaccaagtag ttcaaatgag actagaagta gtcgcagtga agtcaatatg ggtctctcga
    14461 gtgcaggggt tgctgttcaa agaagtgcca gtcgtgttgc ctataatcag tctgctattg
    14521 atgatagtaa taactctgcc tgggattttg cggatggtgt cttggaacaa attctagcga
    14581 cttcacgttc acgtggctat atcactggag accaatatat ccttgaacgt gtcaatatcg
    14641 ttaacggcaa tggttattac aacctctata agccagatgg aacctatctc tttaccctta
    14701 actgtaagac aggatatttt gtcggaaatg gcgctggtca tgcggatgac ttggactact
    14761 aagcagtcgt tacaaaattc tttcttttca aaagtaaaaa tgataaaata aaacaaatga
    14821 aacaagagga gtgtcaaatg acaaaagcta actttggtgt cgtaggtatg gccgtaatgg
    14881 gtcgtaacct tgcccttaat attgaatctc gtggttacac agttgctatc tacaaccgta
    14941 gtaaagaaaa aacggaagat gtgattgctt gccatcctga aaagaatttt gtaccaagct
    15001 atgacgttga aagttttgta aattcaatcg aaaaacctcg tcgtatcatg ctgatggttc
    15061 aagctggacc tggtacagat gctactatcc aagcccttct tccacacctt aacaaggggg
    15121 atatcttgat tgacggtgga aatactttct acaaagatac catccgtcgt aatgaagaat
    15181 tggcaaactc aggtatcaac tttatcggta ctggagtttc tggtggtgaa aaaggtgccc
    15241 ttgaaggtcc ttctatcatg cctggtggac aaaaagaggc ctacgaattg gttgcggatg
    15301 ttcttgaaga aatctcagct aaagcaccag aagatggcaa accatgtgtg acttacatcg
    15361 gtcctgatgg agctggtcac tatgtgaaaa tggttcacaa cggtatcgag tacggtgata
    15421 tgcaattgat cgcagaaagc tatgacttga tgcaacactt gctaggcctt tctgcagagg
    15481 atatggctga aatctttact gagtggaaca agggtgaatt ggatagctac ttgatcgaaa
    15541 tcacagctga tatcttgagc cgtaaagacg atgaaggcca agatggacca atcgtagact
    15601 acatccttga tgctgcaggt aacaagggaa ctggtaaatg gacgagccaa tcatctcttg
    15661 accttggtgt accattgtca ctgattactg agtcagtgtt tgcacgctac atttcaactt
    15721 acaaggaaga acgtgtacat gctagcaagg tgcttccaaa accagctgcc ttcaactttg
    15781 aaggagacaa ggctgaattg attgaaaaaa tccgtcaagc cctttacttc tcaaaaatca
    15841 tttcatacgc acaaggattt gctcaattgc gtgtagcctc taaagaaaac aactggaact
    15901 tgccatttgc agatatcgca tctatctggc gtgatggctg tatcatccgt tctcgtttct
    15961 tgcaaaagat tacagatgct tacaaccgtg atgcagacct tgccaacctt cttttggatg
    16021 aatacttctt ggatgttact gctaagtatc aacaagcagt gcgtgatatc gtagctcttg
    16081 cggttcaagc tggtgtgcca gtgccaactt tctcagcagc tattacttac tttgatagct
    16141 accgttcagc tgaccttcca gctaacttga tccaagcaca acgtgactac tttggtgctc
    16201 acacttacca acgtaaagac aaagaaggaa ccttccacta ctcttggtat gacgaaaaat
    16261 aagtaggtca gccatgggga aacggatttt attacttgag aaagaacgaa atctagctca
    16321 ttttttaagt ttggaactcc agaaagagca gtatcgggtt gatctggtag aggaggggca
    16381 aaaagccctc tccatggctc ttcagacaga ctatgatttg attttattga acgttaatct
    16441 gggagatatg atggctcagg attttgcaga aaaattgagt cgaactaaac ctgcctcagt
    16501 catcatgatt ttagatcatt gggaagactt gcaagaagag ctggaagttg ttcagcgttt
    16561 tgcagtttca tacatctata agccagtctt tatcgaaaat ctggtagcac gtatttcggc
    16621 gatcttccga ggtcgggact tcattgatca acactgcagt ctgatgaaag ttccaaggac
    16681 ctaccgcaat cttaggatag atgttgaaca tcacacggtt tatcgtggtg aagagatgat
    16741 tgctctgacc cgccgtgagt atgacctttt ggcgacactt atgggaagta agaaagtatt
    16801 gactcgtgag caattgttgg aaagtgtttg gaagtatgaa agtgcgaccg agacaaatat
    16861 cgtagatgtc tatatccgct atctacggag caagcttgat gttaaaggcc aaaaaagcta
    16921 cattaaaacc gtgcgtggtg ttggttacac catgcaagaa tagaaaagca gttgcagttg
    16981 tgtaactgct tttttgagga gtttttatat attgacatac aatctagttt ttactacaat
    17041 cgttttagga ggatatataa aatgaagctt ttgaaaaaaa tgatgccaat cgcattagca
    17101 gtctttttct ttggtttgct agcgacaagt acagtatttg cagataccat gggtggccga
    17161 tttgttgata aggataatag aaaatattat gtaaaagatg atcataaagc aatctattgg
    17221 cataaaatag acggtaaaac ttactatttt ggtgatattg gagagatggt tgtcggttgg
    17281 caatacttag aaattcatgg aacaggttat cgtgatgatt tatttgataa tcgtccagtc
    17341 ttcgaaattg gccttcagga gaagtggtac tattttggac aagatggtgc tttgctagaa
    17401 caaacagata aacaagtact agaggcaaaa acgtctgaaa atacaggaaa agtatacggt
    17461 gaacaatatc ctctatctgc tgaaaagaaa acttattatt ttgataataa ttatgctgta
    17521 aagacaggct ggatttatga agacggcaat tggtattatt taaataagct aggaaatttt
    17581 ggcgatgatt cttacaatcc actaccaatt ggtgaagttg ctaagggttg gactcaagat
    17641 tttcatgtta ctattgacat tgatagaagc aaacctgctc catggtacta cctagatcca
    17701 gcaactggca tcatgcaaac tggttggcaa tttctaggta atagatggta ctacctccgt
    17761 tcatcaggag caatggcaac tggttggtat caagatggtt caacttggta ctatttagat
    17821 ccttctaatg gagatatgaa aataggttgg acaaaagtaa atggaaactg gtattatctc
    17881 aattcctctg gagcaatggt tacaggtagc caaactatcg atggtaaagt ttataatttc
    17941 gcctcatctg gtgagtggat ttaatattgg agggtatata gatgaaaatt ttgaaaaaaa
    18001 ctatgcaagt tggactgaca gtatttttct ttggtttgct agggaccagt acagtatttg
    18061 cagatgattc tgaaggatgg cagtttgtcc aagaaaacgg aagaacctac tacaaaaagg
    18121 gggacctcaa agaaacctac tggcgagtga ttgatggtaa gtactattat tttgattctc
    18181 tatctggaga gatggttgtc ggctggcaat atatcccgtt tccatctaaa ggtagtacaa
    18241 ttggtcctta cccaaatggt atcagattag aaggttttcc aaagtcagag tggtactact
    18301 tcgataaaaa tggagtgcta caagagtttg ttggttggaa aacattagag attaaaacta
    18361 aagacagtgt tggaagaaag tacggggaaa aacgtgaaga ttcagaagat aaagaagaga
    18421 agcgttatta tacgaactat tactttaatc aaaatcattc tttagagaca ggttggcttt
    18481 atgatcagtc taactggtat tatctagcta agacggaaat taatggagaa aactaccttg
    18541 gtggtgaaag acgtgcgggg tggataaacg atgattcgac ttggtactat ttagatccaa
    18601 caactggtat tatgcaaaca ggttggcaat atctaggtaa taactggtac tacctccgtt
    18661 catcaggagc aatggccact ggctggtata aggatggttc aacttggtac tacctaaatg
    18721 caagtaatgg agatatgaag acaggttggt tccaggtcaa tggcaactgg tactatgctt
    18781 atagctcagg tgctttggca gtgaatacga ccgtagatgg ctattctgtc aactataatg
    18841 gcgaatgggt tcggtaatga cagggcgctt ataattatat tagaacactc gcttaatcaa
    18901 agaagtgact ttgttgtact tgacctgacg attggggaga ttaaaagcat gtgaaattta
    18961 cacatgcttt ttcgttagtt atgagtgttg aacttgacta accattgaca aaagataaga
    19021 gcaatcaaaa taagatacaa aaatatcaat gctaactgca ccgaaacgcc cgatgctatg
    19081 gacagggcta atagggagag cagggacggg gcgagaatgt ctactgtgct cagagcagag
    19141 cccaccgccc ccatcttgtc actggggata tgggcaaaga cagctgcttg taggcgaggg
    19201 ctgagaatgc cgataatcgt agaactgatg aaactggtca tgaaaattac gatataggct
    19261 tgacaaagga tactagttat tagagccaat agggaaatct cacagaaaac caagaggtgc
    19321 gtgaaacgga tatttttaaa tagattactg ctggtcatat tgccaaggat agctccacaa
    19381 gaaatgatga tggagagcat ggcgaggagt tgcccaatgc tcagttgtgc tagtgtctgt
    19441 tggatgaagc ggagggcaat cagccgaggg gacacatcca agatggcaat catactggtc
    19501 gtcagaaaca gtagtatgac ggtatctttt aacctcagga gcacagccag cgactgttta
    19561 agatgttgaa aatatttctt aaaactcagt gctgtatgtg acatttcaat ccttttttca
    19621 acctcataca aggtatgtct aataacatac agacccaaaa aggcaatgac aaaagtcaga
    19681 gtgttgataa gggaaatagt ttgaatactc ataacattga taaggaatgc gccagccaga
    19741 ttggcgacaa tgtggacaac cctcatcaga gactgcctga accccatggc atcatgcagg
    19801 tcgtccttaa ttacactgat gtagagggcg ttcatcatgt aggcagacag gtagctcaag
    19861 gtgtcagaga tgaggttgat gatgacaatc ataatgactg aaactaatga aaagggcgac
    19921 aagacgagaa atactgtcaa aatagcgtag agcaggattt tgattttggc aatccagagt
    19981 gcgtgtttga ctctattttc ttgaaaatct cctagaatcc cgagaaagag ttgcgatagt
    20041 aggggaacca tctctgaaat ggaaatcagt aaaatcgcta gcggagcgaa attgtactga
    20101 gccacataat tgataatggc gaggtagaaa atactgtcgc cgaatgatga aaaacagctg
    20161 tttagcagca actgtctata tatgttgttt gtccaaaata atttcatact tttctcctta
    20221 tgtctgcaca tcgaatggga atttattatt taatagacac caatataccc catgcttcct
    20281 attccgaagt caaacaaatc tgttttacca ctatctcctt gaaacatcag taaaccgtga
    20341 tcatctcgtt cagaacatgc taaaattacc tgttggattt tttcatcagt aatttgtttt
    20401 gattgtagac agtggtttgt agtaagctag ttattccgtg gcaatatcct gtcatcattt
    20461 ttagatgatg gttaaaaaca aattcttgat atatactaat aatatctttg tttccgtcac
    20521 aatcgtacat acaaagatat aagattattc cggaaattcc ttcgcaccaa gaaagttgta
    20581 aatttcctaa gttttcagta ttagaagtaa ctttttctaa taattttttt aattcagtat
    20641 ggaatgtatg gagatcatta tagaacatag aaggttctaa gactttagaa taggcaaata
    20701 aagcatatgc aattccacaa tatccatgag caaagctata gtctaaaatg ctttctttgg
    20761 ctgtatctct ttgtaggaaa taatgataaa tttcccctat actattgtgg atgaaaattt
    20821 taagagtatt gtcattggta aattgatagt attttattaa tgataatagg acaccagatt
    20881 ttcccaatgc aaagtctatt tcctctagag tatcataatt ctctattaat tttttagcgg
    20941 tgacgtttgc taattgtaga tagtattgat ttttactgat agaaaataaa tgtaggagta
    21001 accatagata gcctgcatca ccaaatagca gtgagtattg atattcatat gtatgtgtcg
    21061 ttctaattgt cactgccttc ttgatgatag agagtatttt agaatccagt tctggggggt
    21121 acaatttatt tagaggaaac agtagtccag ctattccgtg ttggaatgat aaattactta
    21181 cgaaatttcc aaattctgtt gaagaagtga tccttccttc agaatttaca gttttatcta
    21241 gtaaaaatcg tagaacacta ttacattctg ttttgtaatc atatttatgt tcctctattt
    21301 ttttaatttt gactaaatta tttgtttgac ttaaatttag tagatattgt aaccaaaata
    21361 gttgctcatc tgtgagctga ccttgagtat gtgatagttc tagtaattga ataggatcct
    21421 ttaggtagat tcaatcaatc tataacacaa caacataata ataatacttt taggataact
    21481 tgtcaaatat tatagtaaaa tgaaataata acaggacaaa tcgatcagga cagtcaaatc
    21541 gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactatagta
    21601 tatattttta catcttgaat tgtcaaatta agtgtataac tttcccgtag catacttcat
    21661 aaggcgtttt ccacttaaga aattttcgtg gtcgattatt tagaacctgt attcacaaaa
    21721 aaatgttaaa ctagagttat gatacgcaaa gcatatgata ctgatttaaa cgatcaagaa
    21781 tgggcgaaga ttgaacccta tttctccaaa caccgcacct ataaatggcc gaaacgagta
    21841 cttgttaatg agactttgta cgtcactaaa acaggttgtc aatggcgcat gctccctcac
    21901 gactttcctc tttacttaat ggtatggagt ttctttcatc gttctatgac gacaggttgg
    21961 ttccaggtca atggcagatg gtactacgct tatagctcag gtgccttggc agtgaatacg
    22021 accgtagatg gctattctgt caactataat ggcgaatggg ttcaataatg aaagaagcga
    22081 ttgtgaatgg aaacaatcgc tttttttgtg aaaatataat aaaatagata ggaaagaatt
    22141 aatacttgta tgaaaaataa gacgtttttt cgtctagtaa aaggaaaaaa tgacaaaaaa
    22201 agttggtgtc ggtcaggcac atagtaagat aattttaata ggggaacatg cggtcgttta
    22261 cggttatcct gccatttccc tgcctctttt ggaggtggag gtgacctgta aggtagttcc
    22321 tgcagagagt ccttggcgcc tttatgagga ggataccttg tccatggcgg tttatgcctc
    22381 actggagtat ttggatatca cagaagcctg cattcgttgt gagattgact cggctatccc
    22441 tgagaaacgg gggatgggtt cgtcagcggc tatcagcata gcggccattc gtgcggtatt
    22501 tgactactat caggctgatc tgcctcatga tgtactagaa atcttggtca atcgagctga
    22561 gatgattgcc catatgaatc ctagtggttt ggatgctaag acctgtctca gtgaccaacc
    22621 tattcgcttt atcaagaacg taggatttac agaacttgag atggatttat ccgcctattt
    22681 ggtgattgcc gatacgggtg tttatggtca tactcgtgaa gccatccaag tggttcaaaa
    22741 taagggcaag gatgccctac cgtttttgca tgccttggga gaattaaccc agcaagcaga
    22801 agttgcgatt tcacaaaaag atgctgaagg actgggacaa atcctcagtc aagcgcattt
    22861 acatttaaaa gaaattggag tcagtagccc tgaggcagac tttttggttg aaacgactct
    22921 gagctatggt gctctgggtg ccaagatgag cggtggtggg ctaggaggtt gtatcatagc
    22981 cttggtaacc aatttgacac acgcacaaga actagcagaa agattagaag agaaaggagc
    23041 tgttcagaca tggatagaga gcctgtaaca gtacgttcct acgcaaatat tgctattatc
    23101 aaatattggg gaaagaaaaa agaaaaagag atggtgcctg ctactagcag tatttctcta
    23161 actttggaaa atatgtatac agagacgacc ttgtcgcctt taccagccaa tgtaacagct
    23221 gacgaatttt acatcaatgg tcagctacaa aatgaggtcg agcatgccaa gatgagtaag
    23281 attattgatc gttatcgtcc agctggtgag ggctttgtcc gtatcgatac tcaaaacaat
    23341 atgcctactg cagcgggcct gtcctcaagt tctagtggtt tgtccgccct ggtcaaggct
    23401 tgtaatgctt atttcaagct tggattggat agaagtcagt tagcgcagga agccaagttt
    23461 gcctcaggct cttcttctcg gagtttttat ggaccgctag gagcctggga taaggatagt
    23521 ggagaaattt actctgtaga gacagacttg aaactagcta tgattatgtt ggtgctagag
    23581 gacaagaaaa aaccaatctc tagccgtgac gggatgaaac tttgtgtgga aacctcgacg
    23641 acttttgacg actgggttcg tcagtctgag aaggactatc aggatatgct gatttatctc
    23701 aaggaaaatg attttgccaa gattggagaa ttaacggaga aaaatgctct ggctatgcat
    23761 gctacgacaa agactgctag tccagccttt tcttatctga cggatgcctc ttatgaggct
    23821 atggcctttg ttcgccagct tcgtgagaaa ggagaggcct gctactttac catggatgct
    23881 ggtcccaatg ttaaggtctt ctgtcaggag aaagacttgg agcatttatc agaaattttc
    23941 ggtcagcgtt atcgcttgat tgtgtcaaaa acaaaggatt tgagtcaaga tgattgctgt
    24001 taaaacttgc ggaaaactct attgggcagg tgaatatgct attttagagc cagggcagtt
    24061 agctttgata aaggatattc ccatctatat gagggctgag attgcttttt ctgacagcta
    24121 ccgtatctat tcagatatgt ttgatttcgc agtggactta aggcccaatc ctgactatag
    24181 cttgattcaa gaaacgattg ctttgatggg agacttcctc gctgttcgcg gtcagaattt
    24241 aagacctttt tccctagaaa tctgtggcaa aatggaacga gaagggaaaa agtttggtct
    24301 aggttctagt ggcagcgtcg ttgtcttggt tgtcaaggct ttactggctc tctataatct
    24361 ttcggttgat cagaatctct tgttcaagct gactagcgct gtcttgctca agcgaggaga
    24421 caatggttcc atgggcgacc ttgcctgtat tgtggcagag gatttggttc tctaccagtc
    24481 atttgatcgc cagaaggtgg ctgcttggtt agaagaagaa aacttggcga ctgttttaga
    24541 gcgtgattgg ggcttttcaa tttcacaagt gagaccaact ttagaatgtg atttcttagt
    24601 gggatggacc aaggaagtgg ctgtatcgag tcacatggtc cagcaaatca agcaaaatat
    24661 caatcaaaat tttttaactt cctcaaaaga aacggtggtt tctttggtcg aagccttgga
    24721 acaggggaaa tcagaaaaga ttatcgagca agtagaagta gccagcaagc ttttagaagg
    24781 cttgagtaca gatatttaca cgcctttgct tagacagttg aaagaagcca gtcaagattt
    24841 gcaggccgtt gccaagagta gtggtgctgg tggtggtgac tgtggcatcg ccttgagttt
    24901 tgatgcgcaa tcaaccgaaa ccttaaaaaa tcgttgggcc gatctgggga ttgagctctt
    24961 atatcaagaa aggataggac atgacgacaa atcgtaagga cgagcatatc ctctatgccc
    25021 ttgagcagaa aagttcctat aatagctttg atgaggtgga gctgattcat tcttccttgc
    25081 ctctttacaa tctggatgaa atcgatcttt cgacagagtt tgctggtcga aagtgggact
    25141 ttccttttta tatcaatgcc atgactggtg gaagtaataa gggaagagaa atcaatcaaa
    25201 agctggctca ggtggcggaa tcctgtggta ttttatttgt aacgggttct tatagcgcag
    25261 ccctcaaaaa tccaacggat gattcttttt ctgtcaagtc tagtcatccc aatctcctcc
    25321 ttggaaccaa tattggattg gacaagcctg tcgagttagg acttcagact gtagaagaga
    25381 tgaatcctgt tctattgcaa gtgcatgtca atgtcatgca ggaattactc atgcccgagg
    25441 gagaaaggaa gtttagaagc tggcaatcgc atctagcaga ttatagcaag caaattcccg
    25501 ttcctattgt cctcaaggaa gtgggctttg gaatggatgc caagacaatc gaaagagcct
    25561 atgaattcgg tgttcgtaca gtggacctat cgggtcgtgg tggcaccagc tttgcctata
    25621 tcgaaaaccg tcgtagtggc cagcgtgatt acctcaatca atggggtcag tctaccatgc
    25681 aggcccttct caatgcccaa gaatggaaag ataaggtcga actcttggtt agtggagggg
    25741 ttcggaatcc gctggatatg attaagtgct tggtttttgg tgctaaggct gtgggattgt
    25801 cacgaaccgt tctggaattg gttgaaacct acacagttga agaagtgatt ggcattgtcc
    25861 aaggctggaa agcagatcta cgcttgatta tgtgttccct taactgtgcc accatagcag
    25921 atctacaaaa agtagactat cttctttatg gaaaattaaa agaagcaaat gatcagatga
    25981 aaaaggcgta accagcgcct ttttttccat cctcagactg aggtgacttt tttgaattgt
    26041 gataaaatag aagggagagg atgaacctat gagaaaattt aaaatctttt tatttatcga
    26101 agcctgtctt ctgacaggag ctctgatttt gatggtatca gagcattttt cgcgttttct
    26161 gctgatacta ttcctctttt tgcttttgat tcgctactac actggtaaag agggaaataa
    26221 tcttctttta gtagcggcaa ctattctctt ctttttcatc gttatgctca atccttttgt
    26281 gattctagct atttttgttg cggttatcta tagcctcttt cttctttacc cgatgatgaa
    26341 ccaggaaaaa gagcagacca atttggtttt tgaagaggtc gtgacggtta agaaggagaa
    26401 aaatcgttgg tttggaaatc ttcatcattt ttcaagctac cagacttgcc aattcgatga
    26461 tatcaatctc tttcgcttca tgggcaagga cactattcat ctggagaggg tcatcttaac
    26521 caatcatgac aatgtcatta tcctcagaaa gatggtagga acgaccaaaa tcatcgtacc
    26581 tgtagatgtg gaagtcagtc tcagcgttaa ctgtctctat ggggatttga cttttttcaa
    26641 ccagcccaag cgagccctcc gcaatgaaca ctatcatcaa gaaacaaaag actatctcaa
    26701 gagtaacaag agtgtcaaga ttttcttgac cactatgatt ggtgatgtgg aggtggttag
    26761 aggatgaaaa aacaagccta tgtcattatt gctctcacct ccttcctatt tgtctttttt
    26821 ttctcccaca gcttgctgga aatacttgat tttgactggt ctatcttttt gcacgatgtc
    26881 gaaaaaacag aaaaatttgt ctttttattg ttggttttca gcatgtccat gacctgtctc
    26941 ttagtcctgt tttggcgagg gatcgaagag ctttctctaa gaaaaatgca ggctaatctc
    27001 aagcgtttat tggcagggca agaagtagtt caggttgtag atccagattt ggatgccagt
    27061 ttcaagtcct tatcaggtaa acttaacctt ttgacagagg ctcttcaaaa agctgaaaat
    27121 catagccttg ctcaggaaga ggaaatcata gagaaggaac ggaagcgaat tgctcgggat
    27181 ttgcacgata cagtcagtca ggagttgttt gcggcccaca tgattttatc gggtatcagt
    27241 cagcaggctt tgaaattgga tagagaaaag atgcagaccc agttgcagag tgtcacagct
    27301 attttagaaa ctgcccagaa ggatttgcgg gttttgctct tgcatttgcg accagttgaa
    27361 ctggagcaga agagcttgat agaagggatt caaattctct taaaagagct tgaggacaag
    27421 agtgatctta gggttagtct caagcagaat atgacgaaat tgcctaagaa aatcgaggag
    27481 catatcttcc gtatcctgca agagttgatt agcaataccc tccgccatgc ccaggcatct
    27541 tgcctagatg tctacctcta tcagacagat gttgaattgc aactgaaggt ggtggacaat
    27601 gggattggtt tccggttagg aagcttagac gacttgagtt atggactgcg aaatatcaag
    27661 gagagggttg aagatatggc tggaacagtt caactcttga cagctcccaa gcaagggctg
    27721 gcagttgata tccgtattcc cctgttagat aaggaatgat aaaggagtaa agatgaaaat
    27781 tttactagta gatgaccatg aaatggtccg tttgggtttg aaaagctact ttgacctcca
    27841 agacgatgta gaagttgtgg gtgaggcgtc caacgggtct caagggattg acttggcctt
    27901 ggaactgcgt ccagatgtca ttgtcatgga tattgtcatg cctgagatga atgggattga
    27961 cgcgacttta gcaatcctta aagaatggcc tgaagccaag attttgattg tgacctctta
    28021 tttggacaat gaaaaaatca tgccagtctt agatgctggt gccaaaggct atatgctcaa
    28081 gacttctagt gcagatgaat tgcttcatgc cgtcagtaag gtagctgctg gcgagctggc
    28141 cattgagcaa gaggttagca agaaggttga ataccaccgc aatcatatgg aacttcatga
    28201 agaattgact gcgcgtgagc gagatgttct ccaactcatc gccaagggct acgaaaatca
    28261 gcgcatcgca gatgacctct ttatctctct caagacggtc aagacccacg tgtccaatat
    28321 tcttgccaaa cttgaagtca gcgatcgtac ccaggcggct gtctatgcct ttcagcacca
    28381 tttggtgggg caagaggagt tttagatgag tttagcagat ttacttgagg agctagaagc
    28441 agcaaaagac tctaaaaaag caaggtccat ggaagcctat atgcgccatc aattttcttt
    28501 tttaggtatt gcggtgcctg aaagaaataa actctataaa aatattttcc agaagcgaaa
    28561 aaaacaaaga ttatcgattg ggattttgca gacacttgct gggaaaagga gcctagaaaa
    28621 taccaatatg tggctgctaa ctatttgaaa gcaatgcagt cttatctaaa ggaaaccgat
    28681 ttgcctaagc tagagcagtt agtcgtgaca aaatcctggt gggacacggt agatatccta
    28741 gatcgagtag tagggagttt ggtgtatgaa caccctgaac tagaagaaat aatcttaata
    28801 ctcttcgaaa atctcttcaa accacgtcag ctctatctgc aacctcaaaa cagtgttttg
    28861 agcaatctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aaaatggagc
    28921 ctattagata atatctggct gagacgtgtc gctattgacc accagttgtt aagaaaagag
    28981 aagaccaata ctcaattaat ggaaaagatt ctacttcata acttgaacca aacagaattt
    29041 tttatcaata aagctattgg ctggactctg cgagactact ccaaaacgaa tcccacttgg
    29101 gtaacatgct ttattgagaa aaacaaggaa agaatggctg aacttagtat caaagaagca
    29161 agcaagtacc tctagcgtga ttgaaaagcg cagtcattaa ttgaaaagtt tacctgttta
    29221 tgtgataatg gagggtattt aaagaaggtg gtagatttct tgattctata gtagattgag
    29281 aaatttagaa tagtacgcta taattacatt aggaggatac gataatgaag aaaactgttt
    29341 ataaaaaatt gggtatttca attattgcga gtactttatt ggctagccag ttatcgacag
    29401 tatctgcttt gagtgttatt tctagtacag gtgaagaata tgaggtaagt gagacactag
    29461 aaaaaggtcc agggtctaat gattcttcat tatctgagat ttcaccaacg tatggttcat
    29521 actaccaaaa gcaatcagaa gtattatcgg taatgatgat ttgattaaaa ttgataatac
    29581 ttcacagtat ccgtattcga cttcagctat ggttttatct aagtattatg gagtagcaga
    29641 tggaatgaat gtagaaggga ggggaagtgc gaattttatt aaagataatg tgttaattac
    29701 agcggctcac aactactaca gacatgacta tgggaaagaa gcggatgata tttatgttct
    29761 tctggctgtt agtccaagtc aagaaccatt tggaaagatc aaagtaaagg aagttcgtta
    29821 tttgaaggaa tttagaaatt taaattctaa ggatgcaagg gaatatgact tggctttatt
    29881 aattctagaa aagcccattg gtgcaaaatt agggactttg ggtcttccta ctagtcaaaa
    29941 aaatttgaca ggaataactg tgactatcac aggctatcca tcatataatt ttaaaattta
    30001 tcaaatgtat acagataaaa aacaagtttt aagtgatgat ggcatgttct tggattacca
    30061 agttgatact ttagagaggt ctagtggatc tgcagtttat gatgctagtc accgcgtagt
    30121 aggagtgcat actttaggag atggagctaa tcaaattaac agtgcagtta aattaaatga
    30181 acgaaatttg tcatttattt atttattcgg ttcttaaagg ttactctctt gaaggatggt
    30241 gaatgggtta ggtaatgaag gctaattgta aactgtgatg gatacttaac tttgtataat
    30301 aggtggataa aagtctttaa aataggaaaa aacgcatatt attaggtgtt taaaaacctt
    30361 gataatatgc gttttataat ggaaagattt cttcaatttc gtcttgtata gtagattgaa
    30421 actataatag tacacctcta cttctaaaac attgttagaa attgatttga ctgtcctgat
    30481 cgatttgtcc tgttcttatt tcgttttact ataatgtaat cgtccaataa cgaagtgttt
    30541 ttggatagtc cgaaaagttt agcttcatat agagtaattg gtattattga tagagtgtta
    30601 gaaattttaa aagaatatct tcttttagaa gaaggtgatt atatatttac aaataatggt
    30661 tctcccttaa tgataacttg tttcaattac tttttgaaaa acagttttag gaaaagtgaa
    30721 attaagaaag atgattttgt attgactgct catgttttta gatattcgca tataagtttg
    30781 cttgctgaat tggaagtacc tataacagcg ataatggatc gtgtagatta tactaatgaa
    30841 acaaagattt taagtgttta tactcatgtt actgagaaga tgaagtcaaa tataactgaa
    30901 aaattagata aattagtttt ggaaaatgac taaccaaaag atatccaaag tagtctaaaa
    30961 ttgtctatac tttatgagtg ttttagttag gaaaaaggct tgttgtctat aattggctgc
    31021 attagtctag attttattta tagaaaatgt tataatagac tgtatttaaa aaattttaag
    31081 gagaaatgac agaatgtctg tatcatttga aaacaaagaa acaaaccgtg gtgtcttgac
    31141 tttcactatc tctcaagacc aaatcaaacc agaattggac cgtgtcttca agtcagtgaa
    31201 gaaatctctt aatgttccag gtttccgtaa aggtcacctt ccacgtccta tcttcgataa
    31261 aaaatttggt gaagaatcac tttaccaaga cgttatgaac gctcttttgc caaacgctta
    31321 tgaagcagct gtaaaagaag ctggtcttga agtggttgcc caaccaaaaa ttgacgtaac
    31381 ttcaatggaa aaaggtcaag actgggttat cgctgctgaa gtcgttacaa aacctgaagt
    31441 aaaattgggt gactacaaaa accttgaagt atcagttgat gtagaaaaag aagtaactga
    31501 cgctgatgtt gaagagcgta tcgaacgcga acgcaacaac ctggctgaat tggttatcaa
    31561 ggaagctgct gctgaaaacg gcgacactgt tgtgatcgac ttcgttggtt ctatcgacgg
    31621 tgttgaattt gacggcggaa aaggtgaaaa cttctcactt ggacttggtt caggtcaatt
    31681 catccctggt ttcgaagacc aattggtagg tcactcagct ggcgaaaccg ttgatgttat
    31741 cgtaacattc ccagaagact accaagcaga agaccttgca ggtaaagaag ctaaattcgt
    31801 gacaactatc catgaagtaa aagctaaaga agttccagct cttgacgatg aacttgcaaa
    31861 agacattgat gaagaagttg aaacacttgc tgacttgaaa gaaaaatacc gcaaagaatt
    31921 ggctgctgct aaagaagaag cttacaaaga tgcagttgaa ggtgcagcaa ttgatacagc
    31981 tgtagaaaat gctgaaatcg tagaacttcc agaagaaatg atccacgaag aagttcaccg
    32041 ttcagtaaat gaattccttg ggaacttgca acgtcaaggg atcaaccctg acatgtactt
    32101 ccaaatcact ggaactactc aagaagacct tcacaaccaa taccaagcag aagctgagtc
    32161 acgtactaag actaaccttg ttatcgaagc agttgccaaa gctgaaggat ttgatgcttc
    32221 agaagaagaa atccaaaaag aagttgagca attggcagca gactacaaca tggaagttgc
    32281 tcaagtacaa agcttgcttt cagctgacat gttgaaacat gatatcacaa tcaaaaaagc
    32341 tgttgaattg attacaagca cagcaacagt aaaataatct taataaacag aaaacccacc
    32401 tgaattggtg ggttttctga tgcactattt tccaaaaatc tctttgaggt ctgtgtctgt
    32461 aatcccaatc atggctggga tgcggtccca gttttcttcg gttaggatgt aggattgttc
    32521 agaggcactt gatgtgactg tttcagagac agcttgttgc ttttcttcaa cattctccag
    32581 tagatcactg aagcgttcaa tcagataggt ttttcgggca gttccgatgt gttgggtagc
    32641 atagtcgaag gcttgtaatt cgcctagtaa gatgagtttg cttttggcac gtgtaatggc
    32701 tgtgtagatg agatttcgct ccagcatacg tcggctagca ctagtaatcg gtaggatgac
    32761 aactgggaac tcacttccct gagacttatg aatactcatg gcataggcca agcgaatctt
    32821 gtaccattcg ttacgggggt aagagacttc attaccatca aaatcaatga caatctcgtc
    32881 ttgtttcgat tcggtgtatt taccaggaat caggtctgtg atagctccta aatccccatt
    32941 aaagacattg atttcagcat cgttaaccaa atgaatgacc ttgtctctct tacgatagtg
    33001 gcactgagga gcttcaaaac tgagttgatc tttttgtggg ggattgagca ggtcttgcat
    33061 gagctgattg atagcatcaa tccctgccgt ccctcggtac ataggagcca gaacttggat
    33121 atcacgggca ggaataccat ttctgagggc ggcacctaag attttttcaa tggtggcagg
    33181 aatatggcca ctagcaattt caaagtagga acggtcagct tttttttggg tgaaatcagc
    33241 tggcaagatg ccctgtcgaa tctgactagc tagggtgacg atggttgatt ctttgctttg
    33301 tcgataaatt ttttccaagc gagtctgagg aatcaaagga atatgaagca gatccgctag
    33361 aacctgtcca ggactgacag aaggtagctg atcactgtca cctacgatga ggatcttact
    33421 gttagaagag atattggaga agagttgatt ggccagccaa gtatccacca tagagaattc
    33481 atccacgatg ataaagtcag catctaggta atcttccaga tgactggtat catcgtcacc
    33541 tgtcattccc aagtggcgat gtatggtcgc gctaggcaaa cctgtcaatt cattcatgcg
    33601 acgagcagct cgaccagttg gagcagcaag aagaatgggc agattgtttt tcttcctgaa
    33661 gtcaagtcct tctaaaaggg cataaacagc gatgattcca ttgataacag ttgtcttacc
    33721 agtaccaggc ccacctgtca ggataaagac cttgttctgg atagcgtcac aaatagcttg
    33781 tttttgaatg ttatcatact caatccccag ttcttgctcg acagtagtga tatgcttttg
    33841 aatagtttct aaatcttggc tcttctgttt tcctttttca aggatacgaa tcaagtgact
    33901 gcggatacct tcctcagcga aaaagaggct gttgtcaaag atcttggtat caatctgctg
    33961 aaccttgtct tcttcgatca ggtaggagag ctcttgggca acttggctgg ggtctagttc
    34021 cacgggacgg gaagactcaa ggagagtaag ggtttgttcc agcaaatccc gtgcttcaac
    34081 ataggtgtcc cctgtttcca tacaggtctg aaaaagactg tgaactagac cggcgcggaa
    34141 gcgttcagga gcctgacttt cgatgcctag ttcctcagct agttggtcag caatggtaaa
    34201 gcccaaaccc ttgatatcct caaccagttg gtagggataa ttttcaacca catcaagggt
    34261 ttcttccttg taaaagtctt gaatctgaaa ggctagtttg ttgggaatgc cgtagttggc
    34321 tagtttggcc aaaatcatct ccgttccgta gttgagacgg agagtggaga cgaaagcctc
    34381 gcgatttttg gcagagagtc ctgcgatgcc ttctaacttt tctgggtgtt gcaaaatttc
    34441 gtcaatggta ttttcgccat aggcatccac gattttctga gctgtcttga gaccaatccc
    34501 cttgaaatgg ctacttgaaa agtacttgac caagccctta ctagttggtt ttgcgcgatc
    34561 ataacgactg atttgcagtt gttctccata cttggagtgc tggacaattt gcccccaaaa
    34621 agtatagtct tcgccctcaa ttacatcagc catggttcct gtgacaatga tttcaaaatc
    34681 atcaaaatcc tctgcgtccg tatcgtcgat ttctaggagg aggatgcgat aaaaattgct
    34741 gggattttca aaaataatcc gttcaatggt tcctgaaaaa taaacttcca taaaattcct
    34801 ttgcatgaat aggtgagagt tgggattgtt tttattttat actcttcgaa aatatcttca
    34861 aaccacgtca gcttccatct gaaacctcaa aacagtattt tgagctgact tcgtcagttc
    34921 tatccacaac ctcaaaacac tgttttaagc agcctacggc tagcttccta gtttgttctt
    34981 tgattttcat tgagtatttg tcaataaaca atcacttctc acgatagaag aagaggctga
    35041 gattggtgat tctcggcctc ttaggtttct taaaatgttc cgatacgggt gattggccag
    35101 aagcggaatt tagcttcccc tgtgatatct tttgctttga aggtacctac gtggcggctg
    35161 tcgctcgaaa ccaagcggtc atctccgagg agaaggtatt ctccttctgg aacagtaaag
    35221 ctaaagttgg tgttgtagtt gacatcaact gtgaaggctt gggctttttg agcgatactt
    35281 ctaaagaaag ttcctttatt tccttcaaag cccttgcctg agtaagtgct ttggagtttg
    35341 tcatccttga agcgtttgat atagtctgct agataaggct cgtccgtttc tttgtcattg
    35401 atgtagagtt tatcattttc gtaacgaatg gtgtcgccag gcattccaat cacgcgcttg
    35461 acgatgtcct tattgccatc ttcctcatgg gccaccacga tatcaaaacg gtcaatagga
    35521 aggtgtttta caacgaagag aatttcgcca tccgctaggg tcggatccat ggaatgtcct
    35581 tctacgcgaa cattgctcca aaaaaagata cggctcaaag ctagtaatga cagaatcagg
    35641 aggaataatc cccactcttt taagaaattt ttaaataaat tcataactta cctttctaag
    35701 cgtttttcgc tttttcagta tttttaaagt gtagcttagc gcagaagttg agtccctgca
    35761 taccataggc ttgcaaaatc tggctagcca ccttgtcaga agccgttcca gctccacttg
    35821 gaagctgata acccagttct cgtcccaaat tttcaagatt ttccagaaag agatcacgcg
    35881 caatgacaga agaaactgcg acagccaagt atttgccctc agccttttct tctaagctga
    35941 taggattgct gaaacgattg gtctcttgtg ccaagtactt gtcataattt ttagcactgg
    36001 taaaggcatc aatcacaatt ttctcaggct gaacaccttt ttgaaggagg agatagatag
    36061 cctgattatg gagggcaacc ttaatcgaaa cagcattgta gcggtctccg atgacctcgt
    36121 tgtacttgct gggtgagaga aggagtgcct ggtgctgaat tttttccttg agaataggag
    36181 caatctgacg aatcttttgg tcggtcagag tcttagaatc tcccacaccg agttttcgta
    36241 agaaggcatg ctggtcaggt gtgacaaagg aagccacaac tgcaagccca ccaaagtagg
    36301 aaccattccc tacctcatct gtcccaatca aaggaagatt ttgtccgctg gtttgctcta
    36361 cagcttgata gccaaagaaa ctggcgtatt tttcagcccc ttcaccctga agcaagattt
    36421 ttccagaagt atagatagaa accgttgctt gaggtagttt caaaaagtag cggatatagg
    36481 gattcttgct aggagccaga ctggtttgat agtgttcaag aaaagcctga atatcctttt
    36541 cgcttggtgt gagtgtgata cttgccatag tttctattgt accacaaaag cagtaaaatt
    36601 tgtaaaaact gacaaaatta gcgaattttg gtataatatc gtgaggtgaa ttttatggca
    36661 aatctaaatc gattcaaatt tacattcggg aaaaaatcgt taaccttgac aagcgaacat
    36721 gataaccttt ttatggagga aatcgctaag gttgcgacag aaaaatacca agcaattaaa
    36781 gaacaaatgc ctagcgcaga tgatgaaaca atcgctcttt tgttggcagt caactgttta
    36841 tcaactcagc tcagccgtga gattgaattt gacgataagg agcaagagct agaagaactc
    36901 cgtcacaagc ttgtgacttg taagcaagaa cagagcaaga ttgaggattc cttatgattt
    36961 cactccttct tctattggtc ttggtttggg gattttatat cggctatcgg agaggcctgc
    37021 tcttacaggt ttattacctg atttcagcca tggcatcggc ttttatggct ggccagtttt
    37081 ataaggggct tggagagcaa ttccatttat tgctccctta tgcaaattcg caggaaggtc
    37141 aggggacttt ctttttccca tcggatcaac tctttcagct ggataaggtc ttttatgcag
    37201 gtatcggcta cttgcttgta tttgggattg tctatagcat tggtcgtttg cttggtcttc
    37261 tcttacactt gattcctagc aaaaaactgg gtggtaagtt gttccaagtt tcagcaggta
    37321 tcttgtccat gttggtgacc ttatttgtct tgcaaatggc cttgacaatc ttggcgacca
    37381 tccccatggc agttatacaa aatcctcttg aaaagagtat cgtcgcaaaa cacatcatcc
    37441 agagcatacc gataacaacc agttggctca aacaaatctg ggtgacaaat ttaatcggat
    37501 aaaaagggca ggagttttcc tagccctttg tttacagatt tgactcgaat ctatcagaat
    37561 gtaaaaagct accacaccta gacattcaaa gacaaggaaa taaagatgaa taagaaaata
    37621 ttagaaacat tagagttcga taaggtcaag gccttgtttg agcctcattt gttgaccgag
    37681 cagggcttgg agcaattgag acagctggct ccgactgcca aagcagataa aatcaaacag
    37741 gcttttgctg agatgaagga aatgcaggct cttttcgtcg agcaaccgca ttttactatt
    37801 ctctcaacta aggaaattgc aggagtctgc aagaggttgg agatgggagc ggatctcaat
    37861 atcgaggagt tcctactctt gaaacgcgtg cttcttgcca gccgagaact tcaaagtttt
    37921 tacgccaatc tggaaaatgt cagcttggaa gaattagccc tttggtttga gaaattacat
    37981 gattttccgc aattacaagg aaatcttcag gcctttaatg atgcgggttt cattgaaaat
    38041 tttgccagtg aagaattggc gcgaatccgt cgaaaaatac atgatagcga gagtcgggta
    38101 cgcgatgttt tacaagactt gctcaagcaa aaagcgcaga tgttgacaga aggaattgtt
    38161 gctagcagaa atggccgtca ggttttacca gtcaaaaaca cctaccgcaa taagattgca
    38221 ggtgtcgttc atgatatttc tgctagtgga aacaccgtct atatcgaacc acgtgaggta
    38281 gtcaaactga gcgaagaaat tgctagtctg cgagcagatg agcgctatga aatgcttcgc
    38341 attctccaag aaatttctga gcgtgtccgc cctcatgcgg ctgagattgc taatgacgct
    38401 tggattatcg gtcatctgga cttgattcgt gccaaggttc gatttatcca agaaagacaa
    38461 gcagtcgtgc ctcagctgtc agaaaatcaa gagattcaac tgctccatgt ctgccatcct
    38521 ttggtcaaaa atgccgtcgc aaatgatgtc tattttggtc aagatttaac agctattgtc
    38581 attacaggtc ccaatacagg tgggaagacc atcatgctca aaactctggg cttgacacag
    38641 gtcatggccc agtcaggatt gccgatttta gcagacaagg gaagtcgtgt tggtattttt
    38701 gaagaaatct ttgctgatat tggagatgag cagtctattg agcagagctt gtctaccttc
    38761 tctagccata tgaccaatat cgtggatatt cttggcaagg tcaaccaaca ttcactctta
    38821 cttttggatg agttgggggc tggtactgat ccccaagagg gagcagccct tgccatggct
    38881 attctggagg accttcgcct gcgtcaaatc aagaccatgg cgacgaccca ctatccagaa
    38941 ctcaaggcct acggtattga gacagcctgt gtgcaaaatg ccagtatgga gtttgatact
    39001 gcaactcttc gcccgaccta tcgctttatg cagggtgttc ctggccgaag taatgccttt
    39061 gaaattgcca aacgtctagg cctatctgaa gttatcgtag gagatgccag tcagcagatc
    39121 gatcaggaca atgacgtcaa tcgtatcatt gagcaattag aagagcagac gctggaaagc
    39181 cgcaaacgtt tggacaatat ccgtgaggtg gagcaagaaa atctcaagat gaaccgtgcg
    39241 ctaaaaaaac tctacaacga gcttaatcgt gaaaaggaaa ccgagcttaa caaggcgcgt
    39301 gaacaggctg ctgagattgt ggatatggcc ctaagtgaaa gtgaccagat tctcaaaaat
    39361 ctccacagta aatcccaact caagccccac gaaatcattg aagccaaggc caagttgaaa
    39421 aaattggctc ctgaaaaagt ggacttgtct aaaaataagg tccttcaaaa ggccaagaaa
    39481 aaacgagctc caaaggtggg agatgatatc gtggttctca gttatggtca gcgtggtacc
    39541 ttgaccagtc aactcaagga cggtcgctgg gaagcccaag ttggcttgat taagatgacc
    39601 ttggaagaga aagagtttga tcttgttcaa gcccagcaag aaaaaccagt caagaagaaa
    39661 caggtcaatg ttgtgaaacg aacttctggg cgaggacctc aagctagact ggatcttcga
    39721 ggcaagcgct atgaagaagc catgaatgag ctagatacct tcatcgacca agccttgctt
    39781 aacaatatgg ctcaagttga tatcatccat ggtatcggaa caggagtcat ccgtgaagga
    39841 gttaccaaat acttgcaaag aaacaaacat gtcaagagtt tcggctatgc cccacaaaat
    39901 gctggaggca gtggtgcgac tattgtcact tttaaaggat agcagtattc tggactttat
    39961 aaagtaaaaa ctgttgaact aatttttact aataaacaca ttgacaaaag ccaacatttt
    40021 ttgtaaaatt agaatcaatt aaataccaac accgaatgaa gtttaataga agtggggaat
    40081 cgtttgattt tccatgactg taaatggacg gaactctgga gagaccgtaa aggcaccgaa
    40141 ggggcaaggc aggcaactgc tcaaactctc aggtaaaagg acagagctag gatagaccgc
    40201 tttttagcat ttatctaagc attccagagt acatgtatct tgcatgtgct ctttcttttg
    40261 gggttgaaac gataggagaa ggaaatgtta gaattgctta aatcaatcga tgcttttgct
    40321 tggggaccgc ccctcttgat tttattggtc ggaacaggga tttacctaac catgcggcta
    40381 ggactcttgc aggttttgcg tctgcccaag gcctttcagc ttatttttat ccaggataag
    40441 ggacatggtg atgtatccag ttttgcagct ctgtgtacag ccttggcatc aactgttgga
    40501 acaggaaata tcataggagt tgcgacggct atcaaggttg gtggaccagg agctctattt
    40561 tggatgtgga tggcggcttt ctttggaatg gctaccaagt atgcggaagg actcttggcc
    40621 atcaaatacc gcaccaagga cgaccatggt gcagtagcgg gaggtcccat gcactatatc
    40681 cttctaggga tgggagaaaa gtggcgacca cttgctgttt tgtttgcagt agcaggagta
    40741 ttggttgctc tcttgggaat cggaaccttc acccaagtca actcgattac agaatctatc
    40801 caaaatacaa cgacgatttc gccagccatc acagctctcg tcttgtctgt ctttgtagcg
    40861 attgcagtct ttggtggact caagtctatt tctaaggttt caactactgt tgttcctttt
    40921 atggccctca tttatatctt aggaactctt acagttattt tctttaatat cggaaaaatc
    40981 cctggcacaa tcgctttagt ctttacctca gcttttagtc cccttgctgc ggtaggtgga
    41041 tttgctggtg ctagcgttcg gatggctatt caaaatggtg tggcgcgtgg tgtgttctca
    41101 aacgaatctg gtctgggttc tgctcctatt gcagctgcag ctgccaagac aaatgaacca
    41161 gtagagcaag gtttgatttc catgacagga acctttattg ataccctcat catttgtact
    41221 ctaactggtt tgaccatctt ggtaactgga gtttggagtg gtgacttgaa tggggttgcc
    41281 ttgactcagt cagctttctc aacagtcttt tcacactttg ggcctgccct cttgaccatc
    41341 ttccttgtac tttttgcctt tacaacgatt ctaggttgga actattacgg agaacgctgt
    41401 tttgagttcc tctttggggc tcgctttatc tggctctacc gtgtgttttt tgtgctcatg
    41461 gtcttgttag gaggatttat cgagttggat atggtctgga ttatcgcaga tatcgttaac
    41521 gccttgatgg ctctgccaaa cttgattgcc ctcatggtct tgtcgccagt cgttattgct
    41581 gaaactaaaa agtattttga caaataatgg aatcacacag ctcgtgtgat ttttttgcct
    41641 ataaataatt tttatcagcc tgatatataa tatatattat gcaagtgatt ggaagtgtga
    41701 taaactaata taacaacgaa aatcttatga gagaataaag ctttatctta gataaactta
    41761 ggaatcagga ttttataaga ttttccaata atattagtgt caataataag aaaagaggta
    41821 tcttatgaca acatttacta tccatacagt agagtcagca ccagcagaag tgaaagaaat
    41881 tcttgaaaca gtagaaaaag acaacaatgg ctatattccc aacctaatcg gtctcttggc
    41941 caatgccccg actgttttag aagcctacca aattgtctca tctatccacc gtcgcaacag
    42001 cctgacaccc gttgagcgtg aagtggtgca aatcacggca gccgtgacca atggttgtgc
    42061 cttctgtgtc gcaggtcaca cagccttttc catcaaacaa atccagatga atgatgactt
    42121 gattcaagct cttcgcaatc gtactccaat tgaaacagat cctaaattgg ataccctagc
    42181 taagtttacc ttggcagtta tcaataccaa gggtcgtgta ggagatgaag ccttgtctga
    42241 gtttttagaa gctggctaca ctcaacaaaa tgccttggat gtggtttttg gtgtcagcct
    42301 agcaatcctc tgtaactatg ccaacaactt agctaataca ccaattaatc cagaattgca
    42361 accttatgcc taattcatat ctgagtaaaa tgaagtctga aataagcgga cttcgttttt
    42421 ttaaatcctc atttaagcgc ttttatgtta tactgaaact aacatgatta ttggaggtta
    42481 ggatgaaaaa actcccctta gtattttcag gttgtttgct aggtttggca ggagctggaa
    42541 atcttatttt agatacgttg ccggttctat cccatctttt tagtctgact ggtttggttt
    42601 tatggattta ctttctaatt ctgaatctct ttaattggaa agaaaccaag caagaattga
    42661 ccaagccccc tcttttgtca ggaatggcaa cctttcctat ggctgggatg attttatcga
    42721 cctatgtctt tcgcgtattc tcttatcttc ctttggtagc acaagggatt tggtggtttt
    42781 catttctctt ggatttgacc ttgattgctg gttttaccat caagtttgct tgtccagggc
    42841 ggagggttca tgccactcca agctggacgg ttctctatgt ggggatagca gtggctgcct
    42901 tgacctatcc tctggtaggt attatcgaaa ttgcctatgc gaccttgagt tttggttttc
    42961 tcttgacctt ctatctctat ccccttattt atagcgattt aaagaaacat ccactcccac
    43021 tagccttgct tggacaagaa ggaatctact gtgctccttt ctctctactc ttggcttctc
    43081 tagttagagt aggaggaacc agcctgccga cttgggtctt gattgtcatg attttggctt
    43141 ctcaatcctt ctttttcttt gttttaactc gtctgcccaa cattttaaaa caaggttttc
    43201 aaccagcctt ctcagccctc accttcccaa ccattatcac agcgacctcg ctcaagatgg
    43261 ctcagggaat tttgaaactt ccatttctgg attacctggt attggctgaa accattatat
    43321 gcctaactat tttattcttt gtactaggtg cttatctgat ttggttacga aaaaaggtct
    43381 agctagaaat agctaaacct tattttttat ggtttgatga cttcagctcc acccatgtat
    43441 ggacgaagtg cttctgggat ggtcacagaa ccatcttcat tttggtaaat ttcaagaatt
    43501 gcagccactg tacgtccaac tgcaagtcca gaaccgttca aggtatgaag gagtttcacc
    43561 ttgccatctg cttcatcacg gtaacggatt tgggcacgac gggcttggaa atcttctgcg
    43621 tttgaacagc ttgagatttc acggtaattg ttttgtgctg gaatccacac ttccaagtcg
    43681 taagtcttcg cagctgagaa gcccatatct ccagtagaga gagcaacgac acggtatgga
    43741 aggttgagtt tttgaagaat gttttcagcg ttggctgtca ttttttccaa ttcttcgtaa
    43801 gattcttctg gtttggcaaa tttgaccatt tcaaccttgt ggaattggtg caaacggatc
    43861 aagccacgcg tatcacgacc ggcagaacca gcctcagaac ggaatgacgg actcatagca
    43921 gtgaagtaga ttggaagatc tttgccgtct aagatttcat cacggtagta gtttgtcaga
    43981 ggaacttcag cagttggaat caagacaaag ttggtatcgc tgagttcaaa agtatcttcc
    44041 ttaaattttg gatactgacc agtaccaaac atagaatcat ggttgactat gtaaggtgtg
    44101 atgacttcag tatagccttc ttttccatgt tcatccaaca taaagttgta gatagcacgt
    44161 tccaaacgag caccgaggcc tttatagaag aggaagcgag cgcctgttac cttaccaccg
    44221 cgttcccagt caaggatacc aaggtcttca ccgagatccc agtgagcttt aggttcgaag
    44281 tcaaactcgc gtggagtacc ccaacggcga acttccacat tgtcgtcttc gtcagcccca
    44341 acaggaacgc tgtcagctgg gatatttgga agagtcgttg taaattctgt caatttagca
    44401 tcgatttctg ccaattcagc atccaaggct ttaacctcag cagatagatt ttgcatggca
    44461 gcaatcttgt catctgtatt ttccttgttg cgcttagctt gggcaatctc agcagaaact
    44521 gtgttacgtt ctgctttgag agtttcaacc ttgaccaaga tgttacgacg tttagcatcg
    44581 atttctttca tttcattcaa gacagcagca tctacaccac gtgtagctaa tttttctgcg
    44641 acagcttcaa aatctgtacg aatacgtttg atatctaaca taagaactcc tttatgaaaa
    44701 aagcacgcct gacaaaacgt tggagtggca gggccacggt tccatccaac ttcacaggtg
    44761 tgcacttgat tgtgtatgta attgttacta acggtagaat ttcacctatc ccccctatct
    44821 gctcgcagta cccgcagact ttctgaaaga agaagataac ctacttatcc gttgctatga
    44881 ttatactaaa gtttctactt ttttgcaaat agatttttaa atttttggct aattgtctga
    44941 atcagagtcg gaagtttgac gaccttgtca ttgcctagtt tttcgcgtgc aattttgaga
    45001 atggcacctg agtcttttga agcaaagagg aattttcctt tgtctgtaaa gacttcgaag
    45061 tggcggctga ctttgcgtcc agtgacattg gctccaatct gattgatatg gctccaagga
    45121 atctggataa attgttcgac attgacatct gggtaaaatt ccaaagcctg atctccgaca
    45181 aggaatttcc caactttccc agcgatagag aggtaggaag tgcctgtcgt actgaggagt
    45241 actgttttgt taagtgattg agccatgctt agtcttcctt actttctcca aaaaaggcat
    45301 tgtagagggc tttaattgct gctttctctt ggtctttatt gacaacaaac ataatagaaa
    45361 cttcactaga accttgagac atcatctgga tgttgatttt gttttcagat agagcgcgtg
    45421 tcgcagtagc agtcactccg atatggctct tcattttttc accaacaatc ataatgatag
    45481 aaaggtcgtg ttcgatttct gcatgatcta ctttagcctt ttgaaccaac tgacgcagga
    45541 tttcttcttc cttgatggga gttagttggc gagaacggag aatgatagaa agatcgtcga
    45601 tacctgttgg catatgttcc caaccgatgt taagttcttc caggatttgc agaaccttgc
    45661 ggccaaatcc aatctcacgg ttcatgaggt atttcgacat attaatgctg acaaagcctg
    45721 agtcaccagc aattcccaca actggaaatt catcattact gtgttttaga acgatacgag
    45781 tacctggatg gtcagggttg ttggtattct tgataaccag aggaattttt ccacggtagg
    45841 caggaagaag agcctcgtca tgaaggactg agaagcctgc ataggccaac tcgcgcattt
    45901 cacggtaggt caactcagga atcgagtgtg gttggtggat aataccaggg tgggctgcaa
    45961 agataccatc aacgtccgta aagttttcat agaggtcagc tttgacacca gcagcaatga
    46021 tagaacctgt aatatcagat cctccacgtg agaaagtaca gatttgattt tccttagtga
    46081 caccaaagaa accaggaatg acaaggactt cattggtgtt tgtcaattct tcaatcttgt
    46141 cataacttga tggaatgatg cgagcgtgac caggttcact tgtgaccaca atcccagctt
    46201 ctctagggtg catatagcgt gcatcgatac cattttggtt aaagtaggca gcaatcaatt
    46261 tggcattgtt attttcaccg gctgctagga aagtatcgta gagaaattca ttttcttcaa
    46321 taggaagagt ggccaaggcg tgaatgcttt tagaaatttt ttctagcaca gctggtttta
    46381 gtcccaattc actaaccata gcagcatagc ggtcgataat ccagctttgg ctcttgctaa
    46441 tatcgttacc cgcaacatag tcgcggtagt atttaatcag ggcatccgta accttagtat
    46501 cttcagcatt gcgtttacca ggcgcagaaa cgactacaaa acgacgctct gaatcgcttt
    46561 tgacgatgtt taaaactttt tctaattgac tagcagaggc aagagaacta cctccaaatt
    46621 taacaacttt cataagaact cctaaagtaa gtattttata cgattatagc agaaagaaag
    46681 gcttttttca atgaagaaaa taagatgctt tctagcctaa agcgagcctt tcttatcggc
    46741 tgagacactt tcagtcgatt ttttcttgct ttctgctcct aaaaaagata tactttgaca
    46801 gtgaaataat ttaacactca atgaaaatca aagagcaaac taggaagcta gccgcagact
    46861 gctcaaagca ctgctttgag gttacagatg gaagctgacg cggtttgaag agattttcga
    46921 agagtataaa ctgcttataa aataaaaagg agccctgatg gaacacatta tttatcagct
    46981 tgaagaggac ttggcaatcc ttaccttgaa ccgtcctgag gtcgcaaatg gttttcatat
    47041 tcccatgtgt gaggagattt tagaagctct gactttggca gaagaaaatc cagctgtgca
    47101 ttttatctta atcaatgcca atggaaaggt cttctcagtt gggggagatt tggtagagat
    47161 gaagcgggca gtggatgagg atgatattcc atcattgaca aaaatcgcag agttggtcaa
    47221 tacgatttct tataaaatca agcaaatagc caaacctgtt ttaatggaag ttgacggtgc
    47281 tgttgcaggt gccgcagcga atatggctgt tgcggcagat ttctgtttgg cgacggataa
    47341 ggctaagttt atccaagcct ttgttggtgt tggtttggct ccagatgcag ggggaattca
    47401 tctcttgagc cgcagtatcg gtgtgacgcg tgctgctcaa ttagctatga caggagaggc
    47461 tttaacggca gaaaaagccc tagaatgggg gttggtttac cgcgtttctg aagctgaaaa
    47521 acttgaaaag acgagagaac agcttcttaa aaaattaaga cgtgcttcaa gtaattccta
    47581 tgctgccatt aagaagttgg tttgggagag ccagtttaaa gactggcagg gttacgctac
    47641 tttagaactg aacctacaga aatccttagc tcaaacagag gatttcaaag aaggagtgcg
    47701 agctcattcg gagagaagaa gacctaaatt tacaggaaaa taaaaaatac ttgcatcatt
    47761 ctttgaattt tgatataatt ctttctgtca aatgttttga ttgtaaaagt tttttgaaga
    47821 aggagggata tgaaaaatgg actaccaacg aatcaatgaa tatttaacat ctatatttaa
    47881 caatgtcctt gtaattgagg aagtgaactt gagaggtagt cgttttaagg atatctccat
    47941 caaagaaatg catacgattg atgtcatcgg taaggctcca gatgtgactc caagtcaagt
    48001 gtcaaaagag ttgatggtaa ctcttggaac tgttacgaca agtttgaaca atttagagcg
    48061 taagggctac attgagcgag ttcggtcaga acaggatcgt cgtgtggtgc atctgcattt
    48121 gacaaagaag ggtcgcttga ttcatagact gcataaacgc ttccacaagg ccatggtaga
    48181 aaaaattatt gatggcatga gcgaggaaga aattgctgtc atgggtaaag gcttgactaa
    48241 tctttaccaa tttttggagg atttgaaata atggcttttg caaaaataag tcaggttgct
    48301 cattatgtgc cagagcaagt ggttacaaat cacgacttgg ctcagattat ggataccaat
    48361 gatgagtgga tttcaagtcg aacgggaata cgacaaaggc atatttcaag aacagaatct
    48421 accagtgatt tggctacaga ggttgctaag aaactgatgg caaaagctgg aataacagga
    48481 aaagaactgg attttatcat cctagctacc attactccag attcgatgat gccctctaca
    48541 gctgctcgtg ttcaagctaa tattggcgct aataaagcct ttgcttttga cttaaccgcg
    48601 gcttgcagtg gatttgtatt tgctctttca actgctgaaa agtttatcgc ttctggtcgc
    48661 tttcaaaaag gcttggtgat tggtagtgaa accctctcta aggcagtcga ttggtcggat
    48721 cgatcaacag ctgtgttgtt tggagatggt gctggtggtg tcttgttaga agctagcgag
    48781 caagagcatt tcttagctga gagtctcaat agcgatggaa gtcgcagcga gtgtttaact
    48841 tatgggcatt caggtttgca ttctccattt tcagatcaag aaagtgcaga ttcgtttttg
    48901 aagatggatg gacgcacagt ctttgatttt gccattcgag atgtagccaa gtctatcaag
    48961 cagactattg atgaatctcc tatagaggtg acagacttgg attatctgct acttcatcaa
    49021 gccaatgacc gtattttaga taagatggct agaaaaattg gtgttgaccg agccaaactt
    49081 ccagccaata tgatggaata tggcaatacc agtgcagcca gtatcccgat tttactttca
    49141 gagtgtgtag aacaaggtct catcccttta gatggtagcc agactgttct tctatcaggc
    49201 ttcggtggag gcttgacctg gggcacgctc attcttacaa tttaggtaat catgtggtga
    49261 acacattgtt ataaaaaaac tatttatttt aaaggagtcc tatcatggca gtatttgaaa
    49321 aagtacaaga aattatcgtt gaagaacttg gaaaagacgc atcagaagta acacttgaat
    49381 caacttttga tgatttggac gcagattcat tggacttgtt ccaagtaatc tcagaaatcg
    49441 aagatgcttt tgatatccaa atcgaagcag aaaatgactt gaaaacagtt ggtgacttgg
    49501 ttgcttacgt tgaagagcaa gcaaaataag cagaatatta gtagaaggag tagggagaaa
    49561 cccactccct cttgtttagg taatagtttg actgtcaaat tatggtgaaa tcgaactatt
    49621 acgtaagcaa ggaaggttgg aggcactatg aaaacgcgta ttacagaatt attgaagatt
    49681 gactatccta ttttccaagg agggatggcc tgggttgctg atggtgattt ggcaggggct
    49741 gtttccaagg ctggaggatt aggaattatc ggtgggggaa atgccccgaa agaagttgtc
    49801 aaggccaata ttgataaaat caaatcattg actgataaac cctttggggt caacatcatg
    49861 ctcttatctc cctttgtgga agatatcgtg gatctcgtta ttgaagaagg tgttaaagtt
    49921 gtcacaacag gagcaggaaa tccaagcaag tatatggaac gtttccatga agctgggata
    49981 atcgttattc ctgtcgttcc tagtgttgct ttagctaaac gcatggaaaa aatcggtgca
    50041 gacgctgtta ttgcagaagg aatggaagct ggggggcata tcggtaaatt aacaaccatg
    50101 accttggtgc gacaggtagc cacagctgta tctattcctg ttattgctgc aggaggaatt
    50161 gcggatggtg aaggtgctgc ggctggcttt atgctaggtg cagaggctgt acaggtgggg
    50221 acacggtttg tagttgcaaa agagtcgaat gcccatccaa actacaagga gaaaatttta
    50281 aaagcaaggg atattgatac tacgatttca gctcagcact ttggtcatgc tgttcgtgct
    50341 attaaaaatc agttgactag agattttgaa ctggctgaaa aagatgcctt taagcaagaa
    50401 gatcctgatt tagaaatctt tgaacaaatg ggagcaggtg ccctagccaa agcagttgtt
    50461 cacggtgatg tggatggtgg ctctgttatg gcaggtcaaa tcgcagggct tgtttctaaa
    50521 gaagaaacag ctgaagaaat cctaaaagat ttgtattacg gagccgctaa gaaaattcaa
    50581 gaagaagcct ctcgctggac aggagttgta agaaatgact aaaacagcct ttttatttgc
    50641 tggtcaaggt gcccagtatc tagggatggg acgggatttc tatgatcagt atccgattgt
    50701 taaagaaacg attgatcgag cgagccaggt gctaggttat gatttgcgtt atctcatcga
    50761 tacggaagaa gacaaactca atcagacccg ttatacgcaa ccagccattc tagcgacttc
    50821 ggttgctatc taccgtttat tgcaagaaaa gggctatcag cctgatatgg ttgctggttt
    50881 gtctcttgga gaatactctg ccttggtggc aagcggcgcc ttggattttg aagatgcggt
    50941 tgccttggta gctaagcgtg gagcctatat ggaagaagcg gctcctgctg actctggcaa
    51001 gatggtagca gttctcaata cgccagtaga ggtcattgaa gaagcctgtc aaaaagcttc
    51061 tgaacttgga gtggttactc cagccaacta taacacacct gcacaaatcg tcattgctgg
    51121 agaagtggtt gcagttgatc gagcggttga acttttgcaa gaagcaggtg ccaaacgctt
    51181 gattcctctt aaggtgtcag gtccctttca caccgctctc cttgaacctg ctagccagaa
    51241 actagctgaa actctagctc aggtaagttt ttcagatttt acttgtcccc tagtcggcaa
    51301 tacagaagct gctgtgatgc aaaaagagga cattgctcag ctcttgacgc gtcaggtcaa
    51361 ggaacccgtt cgtttctatg aaagtattgg ggtcatgcaa gaagcaggca taagcaactt
    51421 tatcgagatt ggaccgggga aagtcttgtc aggttttgtt aaaaaaattg atcaaactgc
    51481 tcacttagct catgtggaag atcaagcgag tttagtagca cttttagaaa aatagactaa
    51541 aataagtaga agttttgaaa ggaaaaaaat gaaactagaa cataaaaata tctttattac
    51601 aggttcgagt cgtggaattg gtcttgccat cgcccacaag tttgctcaag caggagccaa
    51661 cattgtctta aacagtcgtg gggcaatctc agaagaattg ctcgctgagt tttcaaacta
    51721 tggtatcaag gtggttccca tttcaggaga tgtatcagat tttgcagacg ctaagcgtat
    51781 gattgatcaa gctattgcag aactgggttc agtagatgtt ttggtcaaca atgcagggat
    51841 tacccaagat actcttatgc tcaagatgac agaagcagat tttgaaaaag tgctcaaggt
    51901 caatctgact ggtgccttta atatgacaca atcagtcttg aaaccgatga tgaaagccag
    51961 agaaggtgct atcattaata tgtctagtgt tgttggtttg atggggaata ttggtcaagc
    52021 taactatgct gcttctaagg ctggcttgat tggctttacc aagtctgtgg cacgcgaggt
    52081 cgctagtcgg aatatacgag tcaatgtgat tgctccagga atgattgagt ctgatatgac
    52141 agctatctta tcagataaga ttaaggaagc tacactagct cagattccga tgaaagaatt
    52201 tgggcaggca gagcaggttg cagatttgac agtattttta gcaggccaag attatctaac
    52261 tggtcaagtg gttgccattg atggtggctt aagtatgtag cgaaagctag aggtgaaaag
    52321 aatgaaacta aatcgagtag tggtaacagg ttatggagta acatctccaa tcggaaatac
    52381 accagaagaa ttttggaata gtttagcaac tgggaaaatc ggcattggtg gcattacaaa
    52441 atttgatcat agtgactttg atgtgcataa tgcggcagaa atccaagatt ttccgttcga
    52501 taaatacttt gtaaaaaaag ataccaaccg ttttgataac tattctttat atgccttgta
    52561 tgcagcccaa gaggctgtaa atcatgccaa tcttgatgta gaggctctta atagggatcg
    52621 ttttggtgtt atcgttgcat ctggtattgg tggaatcaag gaaattgaag atcaggtact
    52681 tcgccttcat gaaaaaggac ccaaacgtgt caaaccaatg actcttccaa aagctttacc
    52741 aaatatggct tctgggaatg tagccatgcg ttttggtgca aacggtgttt gtaaatctat
    52801 caatactgcc tgctcttcat caaatgatgc gattggggat gccttccgct ccattaagtt
    52861 tggtttccaa gatgtgatgt tggtgggagg aacagaagct tctatcacac cttttgccat
    52921 cgctggtttc caagccttaa cagctctctc tactacagag gatccaactc gtgcttcgat
    52981 cccatttgat aaggatcgca atgggtttgt tatgggtgaa ggttcaggga tgttggttct
    53041 agaaagtctt gaacacgctg aaaaacgtgg agctactatc ctggctgaag tggttggtta
    53101 cggaaatact tgtgatgcct accacatgac ttctccacat ccagaaggtc agggagctat
    53161 caaggccatc aaactagcct tggaagaagc tgagatttct ccagagcaag tagcctatgt
    53221 caatgctcac ggaacgtcaa ctcctgccaa tgaaaaagga gaaagtggtg ctatcgtagc
    53281 tgttcttggt aaggaagtac ctgtatcatc aaccaagtct tttacaggac atttgctggg
    53341 ggctgcgggt gcagtagaag ctatcgtcac catcgaagct atgcgtcata actttgtacc
    53401 aatgacagct gggacaagtg aagtatcaga ttatatcgaa gctaatgtcg tttatggaca
    53461 aggcttggag aaagaaattc catacgctat ttcaaatact tttggttttg gaggccacaa
    53521 tgcagttctt gctttcaaac gttgggagaa tagataagta tgaatttaaa cgatattaaa
    53581 gacttgatga ctcaatttga ccagtcaagt ttgagagaat tttcttataa aaatgggacg
    53641 gatgagttgc agtttagcaa gaatgaagcg agacctgtgc ctgaagttgc aactcaagtc
    53701 gctccagcac ccgttctagc aacaccgagt ccagtagctc ctacatctgc tccagcagag
    53761 actgtagcag aagaagttcc agctccagct gaagcaagtg tggctagtga gggaaatctt
    53821 gtagagagtc cacttgttgg agtggtttac ttggctgctg gaccagataa acctgccttc
    53881 gttacagttg gtgatagtgt caaaaaaggt caaacattgg taattatcga agccatgaaa
    53941 gtcatgaatg aaatcccagc tcctaaggat ggtgtggtaa cggaaattct cgtctctaac
    54001 gaagaaatgg ttgagtttgg taaaggattg gtacgtatca aatgatcgat attcaaggaa
    54061 tcaaagaagc ccttccccac cgttatccta tgcttctagt ggaccgtgtc ttggaggtga
    54121 gcgaggatac cattgttgct atcaaaaatg tgaccatcaa cgagcctttc tttaacggcc
    54181 actttcctca atacccagtt atgccaggtg ttctgattat ggaagccttg gcgcaaactg
    54241 ctggtgtgtt ggagttatca aaacctgaaa ataaaggaaa actggtcttt tacgctggta
    54301 tggataaggt taagttcaag aagcaagttg taccaggcga ccaattggtt atgacagcga
    54361 cttttgtaaa acgtcgtggc accatagctg tggttgaagc aaaggctgaa gtggatggca
    54421 agcttgcagc cagtggtacc cttacttttg caattgggaa ctaaggaggt tctccatgtt
    54481 tcgaaaaatt ttaattgcca atcgtggtga aattgcggtt cgtattatcc gtgcggcacg
    54541 tgaattgggg attgcgacgg tagcggttta ttcaactgct gataaggaag ctcttcatac
    54601 gctgttggca gatgaagcag tttgtattgg tcctggcaag gcaacagagt cttatctcaa
    54661 tattaatgca gttctatcag ctgcagtctt gactgaggca gaagctattc accctggttt
    54721 tggatttctc agtgaaaatt ccaaatttgc gaccatgtgt gaagaagtag gtatcaagtt
    54781 tatcggtcca tctggtcatg ttatggatat gatgggggat aagatcaatg cgcgtgctca
    54841 gatgattaaa gcaggtgtgc ctgttatacc aggttcagat ggagaagtgc ataactctga
    54901 agaagctttg attgttgctg aaaaaattgg ctatcctgtt atgctcaagg cttcagcagg
    54961 tggaggtggt aaagggattc gtaaggttga aaaaccagat gacctcgttt ctgcctttga
    55021 aactgcctct agtgaggcca aggccaatta tggcaatggt gccatgtaca tagaacgggt
    55081 tatctatcca gctcggcaca ttgaggttca aatcctaggt gatgagcatg gacatgtgat
    55141 tcacttgggt gaacgggatt gttctcttca aaggaataac caaaaggttt tggaagaaag
    55201 tccctcgatt gcaatcggaa aaacgctgcg tcatgaaata ggtgctgctg ctgttcgagc
    55261 ggcagagttt gttggctatg agaatgcagg aaccattgaa tttcttcttg atgaagcaag
    55321 tagcaatttc tatttcatgg agatgaatac tcgtgttcag gtagaacatc cagtaacaga
    55381 gtttgtttca ggtgttgata tcgttaagga acagatttgc attgcggcag gtcagccttt
    55441 gtctgttaag caagaagata ttgtcctacg cggtcatgcc atcgagtgtc gtatcaatgc
    55501 agaaaaccca gcctttaact ttgctccaag tccaggtaag attactaatc tctatctgcc
    55561 aagtggtgga gttggcttgc gcgtggattc agcagtttat ccaggttata ccattccgcc
    55621 ttattatgat agtatgattg ccaaaatcat agtacacggc gaaaatcgtt ttgacgcctt
    55681 gatgaaaatg caacgtgccc tctatgaatt agaaattgaa ggagtgcaga ccaatgcaga
    55741 tttccagctt gacctcattt cagatcgcaa tgtcattgct ggggattatg atacttcctt
    55801 cttgatggaa accttcttac ctaaatatca agaaaaagaa taaaatgact ttaagagttt
    55861 aaaccgaaaa ggggaatcaa tggctctatt tagtaaaaaa gataagtata ttcgaatcaa
    55921 tcccaatcgt tcggttaggg aaaaacctca agctaagcca gaggttccag atgaattatt
    55981 ttcccagtgt ccaggctgta agcataccat ctatcagaag gatctgggaa gtgaacgtat
    56041 ctgtccgcac tgtagctata cctttcgtat ttctgcccaa gaacgcttgg ctttgacgat
    56101 tgatatggga accttcaaag aattgtttac agggattgaa agcaaggatc ccttgcattt
    56161 ccctggttac caaaagaaac tggcatctat gcgtgaaaaa acaggtctgc atgaagccgt
    56221 tgtgacagga actgctctta ttaaaggtca gactgtggct cttgggatta tggattctaa
    56281 ctttatcatg gcttctatgg gtacggttgt aggtgaaaaa atcactcgtt tgtttgagta
    56341 tgcgactgtc gaaaaattgc cagttgtcct attcacagcc tctggtggag cccgtatgca
    56401 ggaaggaatc atgagtctca tgcagatggc taagatctct gcggcggtta aacgccattc
    56461 aaatgctggt ctcttttacc tgaccatttt gacagatcca acgactggtg gtgtgacagc
    56521 ttctttcgct atggaaggcg atatcattct ggctgaacca cagagcttgg ttggttttgc
    56581 tgggcgtcgt gtgattgaaa atacggttcg tgaaagcttg cctgaggatt tccaaaaggc
    56641 agaattccta ttagaacatg gctttgtgga tgctattgtc aaaagaagag acttaccaga
    56701 tacgattgct agcctagtca gattgcatgg agggagtcct agatgaatat tgcaaaaata
    56761 gtcagagaag cgcgtgagca gagtcgcttg acaaccttgg actttgcgac aggcattttt
    56821 gatgaattta tccaattaca tggtgaccgt tcttttcgtg atgatggtgc agttgttggt
    56881 ggtattggtt ggcttggaga tcaagctgta acagtggttg gtatccaaaa aggcaagagt
    56941 ttgcaagaca acctcaaacg gaattttggc caaccacatc cagaaggcta ccgaaaggca
    57001 ctgcggttga tgaaacaggc tgagaaattt ggccgtccag ttgtgacctt tatcaataca
    57061 gcaggtgctt atcctggtgt cggagcggaa gaacgtggtc aaggggaagc tatcgctcgc
    57121 aatctcatgg aaatgagtga cctgaaagtt cctattatcg ccattattat cggtgaaggt
    57181 ggttcaggcg gggctctggc tctagctgtc gcggaccgtg tctggatgct ggaaaattct
    57241 atctatgcca ttctcagtcc agaaggcttt gcttccattt tatggaagga cggtactcgc
    57301 gctatggaag cagcagaact gatgaaaatc acttcgcatg aactgttaga aatggacgtg
    57361 gtggataagg tgatttctga agtaggactt tctagtaaag aactgattaa gagtgtcaaa
    57421 aaagaactcc aaacggagct ggctagactt tcacaaaaac cgctagaaga gttgctggaa
    57481 gaacgctatc aacgatttag aaaatactaa gaatgactaa atgagactag aaaggtctca
    57541 ttttttatgg aaaaatgcaa ttcaggttga aaaattgaca gttgaggaga tagactataa
    57601 aatagacaaa aaagatgtat actgtagatg taagcttaca aaaatttata gtgtattgaa
    57661 tctat
//
LOCUS       DAVDFK010000011        56257 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.11, whole genome shotgun sequence.
ACCESSION   DAVDFK010000011 DAVDFK010000000
VERSION     DAVDFK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56257
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.11"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(447..2174)
                     /gene="ezrA"
                     /locus_tag="VUR04_000807"
     CDS             complement(447..2174)
                     /gene="ezrA"
                     /locus_tag="VUR04_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET5340732.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2256..4202)
                     /gene="gyrB"
                     /locus_tag="VUR04_000808"
     CDS             complement(2256..4202)
                     /gene="gyrB"
                     /locus_tag="VUR04_000808"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET5340733.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4217..4780)
                     /locus_tag="VUR04_000809"
     CDS             complement(4217..4780)
                     /locus_tag="VUR04_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5340734.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTGIVNLRQVLDI"
     gene            complement(4865..5419)
                     /locus_tag="VUR04_000810"
     CDS             complement(4865..5419)
                     /locus_tag="VUR04_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET5340735.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5430..6653)
                     /locus_tag="VUR04_000811"
     CDS             complement(5430..6653)
                     /locus_tag="VUR04_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET5340736.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6690..9140)
                     /locus_tag="VUR04_000812"
     CDS             complement(6690..9140)
                     /locus_tag="VUR04_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET5340737.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQYILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9340..10269)
                     /locus_tag="VUR04_000813"
     CDS             complement(9340..10269)
                     /locus_tag="VUR04_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET5340738.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLCEIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10409..10696
                     /locus_tag="VUR04_000814"
     CDS             10409..10696
                     /locus_tag="VUR04_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET5340739.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10730..12064)
                     /gene="ciaH"
                     /locus_tag="VUR04_000815"
     CDS             complement(10730..12064)
                     /gene="ciaH"
                     /locus_tag="VUR04_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET5340740.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12054..12728)
                     /gene="ciaR"
                     /locus_tag="VUR04_000816"
     CDS             complement(12054..12728)
                     /gene="ciaR"
                     /locus_tag="VUR04_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET5340741.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12837..15383)
                     /locus_tag="VUR04_000817"
     CDS             complement(12837..15383)
                     /locus_tag="VUR04_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET5340742.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15506..15946)
                     /locus_tag="VUR04_000818"
     CDS             complement(15506..15946)
                     /locus_tag="VUR04_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET5340743.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15921..16790)
                     /locus_tag="VUR04_000819"
     CDS             complement(15921..16790)
                     /locus_tag="VUR04_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET5340744.1"
                     /translation="MKNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRDLNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESLIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16832..17560)
                     /locus_tag="VUR04_000820"
     CDS             complement(16832..17560)
                     /locus_tag="VUR04_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340745.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGLAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17568..18047)
                     /locus_tag="VUR04_000821"
     CDS             complement(17568..18047)
                     /locus_tag="VUR04_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5340746.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLVYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18058..18756)
                     /locus_tag="VUR04_000822"
     CDS             complement(18058..18756)
                     /locus_tag="VUR04_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET5340747.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPAE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18749..18985)
                     /locus_tag="VUR04_000823"
     CDS             complement(18749..18985)
                     /locus_tag="VUR04_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET5340748.1"
                     /translation="MTFEEILPGLKDKKKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19085..20011)
                     /locus_tag="VUR04_000824"
     CDS             complement(19085..20011)
                     /locus_tag="VUR04_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET5340749.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALIESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20086..20901)
                     /locus_tag="VUR04_000825"
     CDS             complement(20086..20901)
                     /locus_tag="VUR04_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340750.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIVTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20905..21225)
                     /locus_tag="VUR04_000826"
     CDS             complement(20905..21225)
                     /locus_tag="VUR04_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET5340751.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21511..23508)
                     /gene="metG"
                     /locus_tag="VUR04_000827"
     CDS             complement(21511..23508)
                     /gene="metG"
                     /locus_tag="VUR04_000827"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET5340752.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYYV
                     FYLTGLDEHGQKIQQKAEEAGITPQTYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDSLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGYGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23632..24891)
                     /locus_tag="VUR04_000828"
     CDS             complement(23632..24891)
                     /locus_tag="VUR04_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340753.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24893..25594)
                     /locus_tag="VUR04_000829"
     CDS             complement(24893..25594)
                     /locus_tag="VUR04_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340754.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25578..26777)
                     /locus_tag="VUR04_000830"
     CDS             complement(25578..26777)
                     /locus_tag="VUR04_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET5340755.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27063..28409
                     /gene="gor"
                     /locus_tag="VUR04_000831"
     CDS             27063..28409
                     /gene="gor"
                     /locus_tag="VUR04_000831"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET5340756.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTSKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            28606..29142
                     /locus_tag="VUR04_000832"
     CDS             28606..29142
                     /locus_tag="VUR04_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET5340757.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKTLVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(29346..29561)
                     /locus_tag="VUR04_000833"
     CDS             complement(29346..29561)
                     /locus_tag="VUR04_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET5340758.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29659..29979
                     /locus_tag="VUR04_000834"
     CDS             29659..29979
                     /locus_tag="VUR04_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340759.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30009..30347)
                     /locus_tag="VUR04_000835"
     CDS             complement(30009..30347)
                     /locus_tag="VUR04_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340760.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30359..31078)
                     /gene="trmD"
                     /locus_tag="VUR04_000836"
     CDS             complement(30359..31078)
                     /gene="trmD"
                     /locus_tag="VUR04_000836"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET5340761.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31068..31586)
                     /gene="rimM"
                     /locus_tag="VUR04_000837"
     CDS             complement(31068..31586)
                     /gene="rimM"
                     /locus_tag="VUR04_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET5340762.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPSKRV
                     DVEILEGLDDED"
     gene            complement(31617..32405)
                     /locus_tag="VUR04_000838"
     CDS             complement(31617..32405)
                     /locus_tag="VUR04_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5340763.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQALVAIEPTTKKVMFADFSENPYPEMEEQMRLIDEYGPELYFKNLT
                     QATFSPETNKEIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32509..32752)
                     /locus_tag="VUR04_000839"
                     /pseudo
     CDS             complement(32509..32752)
                     /locus_tag="VUR04_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(32982..33221)
                     /locus_tag="VUR04_000840"
     CDS             complement(32982..33221)
                     /locus_tag="VUR04_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET5340764.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33241..33513)
                     /gene="rpsP"
                     /locus_tag="VUR04_000841"
     CDS             complement(33241..33513)
                     /gene="rpsP"
                     /locus_tag="VUR04_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET5340765.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33683..33892
                     /locus_tag="VUR04_000842"
     CDS             33683..33892
                     /locus_tag="VUR04_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340766.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            34371..34583
                     /locus_tag="VUR04_000843"
     CDS             34371..34583
                     /locus_tag="VUR04_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340767.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            34666..35469
                     /locus_tag="VUR04_000844"
     CDS             34666..35469
                     /locus_tag="VUR04_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET5340768.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35525..37066)
                     /locus_tag="VUR04_000845"
     CDS             complement(35525..37066)
                     /locus_tag="VUR04_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5340769.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37068..37541)
                     /locus_tag="VUR04_000846"
     CDS             complement(37068..37541)
                     /locus_tag="VUR04_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET5340770.1"
                     /translation="MTKKRELILRLGVAVYSLCIVYFCFTPQATVEVGTPGIQHLGRL
                     VFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKKVLL
                     FSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN"
     gene            complement(37543..38628)
                     /gene="rlmN"
                     /locus_tag="VUR04_000847"
     CDS             complement(37543..38628)
                     /gene="rlmN"
                     /locus_tag="VUR04_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET5340771.1"
                     /translation="MKPSIHSLTRQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVDCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITVSTSVLAHKIRNFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     FAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEYGT
                     DIDAACGQLRSNTMKRDRQKAVAEVNP"
     gene            complement(38649..39179)
                     /locus_tag="VUR04_000848"
     CDS             complement(38649..39179)
                     /locus_tag="VUR04_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET5340772.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISCLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(39336..39941)
                     /locus_tag="VUR04_000849"
     CDS             complement(39336..39941)
                     /locus_tag="VUR04_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET5340773.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADIESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40114..41151)
                     /locus_tag="VUR04_000850"
     CDS             complement(40114..41151)
                     /locus_tag="VUR04_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET5340774.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41185..42120)
                     /locus_tag="VUR04_000851"
     CDS             complement(41185..42120)
                     /locus_tag="VUR04_000851"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET5340775.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42673..43863)
                     /locus_tag="VUR04_000852"
     CDS             complement(42673..43863)
                     /locus_tag="VUR04_000852"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET5340776.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(44240..45583)
                     /locus_tag="VUR04_000853"
     CDS             complement(44240..45583)
                     /locus_tag="VUR04_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5340777.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGCLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVKNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45723..46538)
                     /locus_tag="VUR04_000854"
     CDS             complement(45723..46538)
                     /locus_tag="VUR04_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET5340778.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYNLICFQEINQEM
                     TSSEVEVNDLYQALPAAESIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(46590..48770)
                     /locus_tag="VUR04_000855"
     CDS             complement(46590..48770)
                     /locus_tag="VUR04_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5340779.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAADSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(49056..49982)
                     /locus_tag="VUR04_000856"
     CDS             complement(49056..49982)
                     /locus_tag="VUR04_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5340780.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(49975..50667)
                     /gene="ftsE"
                     /locus_tag="VUR04_000857"
     CDS             complement(49975..50667)
                     /gene="ftsE"
                     /locus_tag="VUR04_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET5340781.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(50685..51780)
                     /gene="prfB"
                     /locus_tag="VUR04_000858"
     CDS             complement(join(50685..51707,51709..51780))
                     /gene="prfB"
                     /locus_tag="VUR04_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET5340782.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(51888..52544)
                     /locus_tag="VUR04_000859"
     CDS             complement(51888..52544)
                     /locus_tag="VUR04_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5340783.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQSFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(52852..53562)
                     /locus_tag="VUR04_000860"
     CDS             complement(52852..53562)
                     /locus_tag="VUR04_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340784.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(53562..54326)
                     /locus_tag="VUR04_000861"
     CDS             complement(53562..54326)
                     /locus_tag="VUR04_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340785.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPVFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(54326..55282)
                     /locus_tag="VUR04_000862"
     CDS             complement(54326..55282)
                     /locus_tag="VUR04_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET5340786.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(55286..56155)
                     /locus_tag="VUR04_000863"
     CDS             complement(55286..56155)
                     /locus_tag="VUR04_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET5340787.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
BASE COUNT        16817 a        12316 c        10057 g        17067 t
ORIGIN      
        1 aaactctcgt aaacaaagag gttttagagg cctatttacc gtggactaaa gttgtacaag
       61 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct agcctggaga
      121 tttttcaata gacttcgtta ttggacggtt accaagttac tcaaagtaca gatttgaagc
      181 tgcagataag actgacgaaa tcactttaat actaaatgaa aatcaaaaag caaactaaga
      241 agctagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt tgaagagatt
      301 ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggt aaaaactcaa
      361 tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg attctgctcc
      421 tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt tttctcatat
      481 gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg agaaatctta
      541 tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc gttaaatgct
      601 tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgtaataa ttgttctgtc
      661 aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat atcattcgtt
      721 gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc taactcaacc
      781 attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt ttgtggaata
      841 cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt gacataaaca
      901 ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg ctcactaact
      961 gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag attttcttca
     1021 agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac aatagctgcc
     1081 tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt ctcaggaagt
     1141 aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt ctctttcata
     1201 tgttgaagat aagttggaag agttgcaagt agattttcca ctactttctg agcagcaatt
     1261 tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc attctcatat
     1321 tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa tgcttcataa
     1381 agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc atcaattagt
     1441 ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga aagcgtcgta
     1501 accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt ttctgtatta
     1561 tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac aaattgtgaa
     1621 aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg accatactgt
     1681 tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc atgaagaaca
     1741 cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg aattgccgca
     1801 atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg actggccttg
     1861 agaaaacgaa atgaatggtt atagccttct gcttcaaaga gattattttc aatatcggca
     1921 aaagagttga gagataaatc aacccatttt tgattccatt cacggaaagc cacttgactt
     1981 tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg aagattgtat
     2041 aattcttctt ttctttcttc tagcgcctct aatctcccct cgtttcgctt acgtagaaag
     2101 attgccacta cataagccag aactaaaatg actgcaattg caaccattaa ataaattagt
     2161 tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga ttatatcata
     2221 ttttttagac caagggaact acttctccct attttttaga catcaagtgt actatagaca
     2281 gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa catatcaaag
     2341 attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg atgttcggga
     2401 tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt ataacgctga
     2461 atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag tttgatttct
     2521 tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac accatagatt
     2581 ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata acgataaatc
     2641 aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt catcaaaacg
     2701 agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt tcccatggct
     2761 gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc tttttcaacg
     2821 ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg accagatttg
     2881 gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc agggttatta
     2941 gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga ttttttacgt
     3001 gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat tcctttttct
     3061 acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc ttcactgaag
     3121 aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt ttgtccttca
     3181 aactgtggat ttgggtgttt aactgagata actgcagtta agccttcgcg aacatcttcc
     3241 cctgttaggt tgtcttcatt gtctttcagt aacttatttt tacgagcata atcgttgata
     3301 acacgtgtca aggctgtacg gaaaccttgt tcatgcgttc caccttcatg tgtatgaata
     3361 ttattggcga aactcatgac attttcatgg taacccgttg tgtactgcat ggctacctca
     3421 actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat tacatccttg
     3481 ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata atgcttggtt
     3541 tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt tagaaaggcc
     3601 aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc agtgaagatt
     3661 tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc aactatttca
     3721 agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc atttttgtga
     3781 acatgaacgt ctaattgagt tgaaagggca ttaacaactg acgaccccac cccgtgaaga
     3841 ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag gactgtaaag
     3901 acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat accacgccca
     3961 tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg gctggcaaat
     4021 cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg gtgaagacct
     4081 tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc taagccctct
     4141 aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat ttcttctgtc
     4201 atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata ccggtaaaca
     4261 agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga tcaccaatga
     4321 caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg ggatttggct
     4381 ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct atagaggttt
     4441 tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga cggccacctt
     4501 gatttgaaat gtcttccaat aggtcagaaa ctccttcaaa taaaatcggg tgttcaagct
     4561 ctctagcttc attttccttg tacttttcta aaaaattctc taaattggga gcgaatgtct
     4621 caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg tcttgtgtga
     4681 taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa ttatccagta
     4741 aagttccacc taaatcccag atgtaatcgt gatatttcat acccttcatt atagcatttt
     4801 tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga gaataactcc
     4861 cgttttactg atttttacca aagacatctc gatagagcat tcctgttcgt aaactctctg
     4921 cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt gaaggacccc
     4981 gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga ccatcaagga
     5041 tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc tctgcttgat
     5101 tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc tcgaagcttt
     5161 gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc atacctccag
     5221 gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct gctcttactt
     5281 ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat gtgatattgg
     5341 ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc tgagctaaca
     5401 taactgctac ttttaccatg attttctcct tatttaattt gttttaatac aacctttttc
     5461 cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta actcatcgat
     5521 aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg cgaaatgaaa
     5581 ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt ctcaaagatg
     5641 tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg gttatttgat
     5701 ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat aaccaggaca
     5761 gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga ctctcgaact
     5821 gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact cccaatggca
     5881 atctgccctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg attgagccaa
     5941 gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa agctcgtccg
     6001 tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt cacaaatact
     6061 gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa aatggctaca
     6121 aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac tggaatggta
     6181 aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct ccattcctta
     6241 tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga tatcttcata
     6301 aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt ggcacccgtt
     6361 gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc caagcctaaa
     6421 atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat gaccacaaaa
     6481 ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg cagaatatta
     6541 ttgggataat catgactaac ggctatatag atagccacca caccgatgac cagtagaaaa
     6601 aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt catatatact
     6661 aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct atcaatagcc
     6721 tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag agatgctact
     6781 atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt taaggaacgt
     6841 tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat ggccattggc
     6901 aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt aatctttttc
     6961 gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat cacaaaagga
     7021 tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat ttgttgttca
     7081 cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg ggccaagtgg
     7141 ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa gagaaccaaa
     7201 atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct ggcatagact
     7261 tctaaggagg tttctgttac cagagggaaa tctttgacca tgaccacttc ttgttcctgt
     7321 tttccccgag attcaatctt gacaaattta gcttcaggat agcctaaaag gtctgccaaa
     7381 gaaaccctct gactaatctc aagagtagcc gatactccca ggacttggca actctcagga
     7441 agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat tttcttttga
     7501 ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg aaccagctca
     7561 tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattatccag agaatctaag
     7621 atatttttcc tagatttgcc agactgaaat tgttctatca agtagagaca ctcaaagcga
     7681 atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc cttatcaatt
     7741 aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag agctaacaaa
     7801 atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg attatcttca
     7861 agtctggtca cgagataggc atgattagtc actaaaagct tgcaagtctc tgccctttct
     7921 tgactacgtt tccaaaaatc ttccgtcaca aataagctat gggatgataa attcccatca
     7981 tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc atccaaatct
     8041 cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct aaataagcga
     8101 ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata attttgtggt
     8161 ccctttaagc tatgaatatc tgtatggaac acttccttga gacgtttacc ttcttcttcc
     8221 atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg ctctttggat
     8281 tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg cgcttgaatc
     8341 agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact ttcttgttcc
     8401 tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga tagttttcgt
     8461 ggctccagag aagctgccgt tttcttaaaa tacagacctt gaacttggac caagtctgga
     8521 gaactcagga tatattggtt gcgataagtt tcctcaataa ccaggtagga ctcatatagg
     8581 agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg ggtcatcttt
     8641 tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc tgtgtgtgcg
     8701 tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt ttccagttca
     8761 gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag ctcatagcct
     8821 tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg ggctacaaaa
     8881 atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc aggtgcttgc
     8941 gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa gggttcatgt
     9001 ggattgacat ccgtcgtata gtgatcgacg atttctccgt cctcaatcac gacaattccc
     9061 acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac cacaacatag
     9121 cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat ttggcacctg
     9181 caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc ccatcgaata
     9241 gagcattcta gcctgctgat ttttttaaaa tagtgaagaa atacgaaaaa ttgagagaag
     9301 aaatgttttc atcttccttc tctcaacgaa tcatgtattt tatttaacca tgtcaggatc
     9361 gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac gaacttcttc
     9421 atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt tacgcgcttg
     9481 gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc cttctagttt
     9541 ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat caaggtcatt
     9601 gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc tctctggatc
     9661 acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga tatgtgtaaa
     9721 gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag caccgtaaac
     9781 caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag ctgatggaat
     9841 ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt taatctgacg
     9901 actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac catcgcggtt
     9961 aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga tttcttccaa
    10021 gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag cattgaccgc
    10081 aacgagcaat tccttaccag catcatgaac caacttagcg atttcacata attggtcata
    10141 actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga tacggtctac
    10201 gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg taatgacaat
    10261 cttttccata agaaaaatta taccacattt ctccaaaatc agccatgctt tgaaaatgaa
    10321 aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa aaatgataaa
    10381 ataggtatgt actgttaagg agagaatcat gcccgtaaga aaattacaat cctatgaggt
    10441 agactatcaa gaagaattaa accagcagct tcctcattac caagcttata cacctgaagc
    10501 gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg ttttttgtat
    10561 ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg ctcttgcctt
    10621 tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta ttatcaaacg
    10681 aaaacgtaga agataaatcc aaaatatcgc cccaattgga gcgatatttt tattttttct
    10741 ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg ggtttattat
    10801 ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg gataatccta
    10861 aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa cggtcaaaaa
    10921 ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt aaataaagat
    10981 tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta tacttgacgg
    11041 cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg acaattgttc
    11101 gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc atctcatagt
    11161 ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc ttaatcccat
    11221 catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt cggacttctt
    11281 ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc ttacgaaaaa
    11341 gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga ctggcatttt
    11401 ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg accctagcta
    11461 gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgatc acaatcaatt
    11521 gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca gcagcatact
    11581 tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga tagatttctt
    11641 cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct ttcttttcta
    11701 acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta aagtccttat
    11761 caaagagaat gacttccgta ttggaactga cattaggttt tatttctact ttactagcgt
    11821 ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata gccagctgaa
    11881 taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa gtataaagac
    11941 tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg gtgaagacac
    12001 cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta agtttactga
    12061 acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc aaaagtggtt
    12121 ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat cgttgtatca
    12181 ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac attttgattt
    12241 tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg agtatcttca
    12301 actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa ggtattttca
    12361 ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc ttctaggtag
    12421 aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt gtcatccaaa
    12481 ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg caattctttt
    12541 aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa gtcatagaca
    12601 ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac atccgcaaaa
    12661 tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac caataagatt
    12721 tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct taaaaaaaac
    12781 tcaactctct gcattttaca tgagatagct gagttttctt tttattttag gcttatttat
    12841 gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct aatcaagtca
    12901 acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc aaggtcagaa
    12961 agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt aaatacatga
    13021 gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc cttaatccaa
    13081 gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg agctaggaat
    13141 tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt ccaagaagta
    13201 atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc caactggcgt
    13261 ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa caagtcttta
    13321 gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc tgggagtcct
    13381 gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc ttctgcatca
    13441 tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc atctgattct
    13501 ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt agcaaccagt
    13561 cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag ggctgaaatc
    13621 acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt atcaagaact
    13681 ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg ttcttgaaca
    13741 atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc ttctaacaag
    13801 tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg aagagctcct
    13861 tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt ttcgagtgta
    13921 tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt cttgtcttcg
    13981 ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc aactttgaca
    14041 gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc gacatcacgt
    14101 cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct gtattggtgt
    14161 ttttcaaagt aggcatgcaa acctttagca aaatcagcat ctcctagcca acggcgaagc
    14221 atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag tgtattgatt
    14281 tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc gtcacgttca
    14341 agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct tggttcgatg
    14401 gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca aaggtcatcc
    14461 caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg ggccacaaca
    14521 agggcaactt gttgacggct agcaaatgta gagttctcat cgacaaccaa gtaaacttca
    14581 cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg aagggcgatg
    14641 tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa ctcgatagag
    14701 cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt ggttgagtag
    14761 acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc accagcaaca
    14821 aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat acctgtttcc
    14881 ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc ttctgcttgg
    14941 tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac acatgggaaa
    15001 gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt gactccatca
    15061 actgtataat aagaagggta aatccctgtc atgttatctg taattttacc agaaaaggca
    15121 agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc attgtcatgg
    15181 tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc caagtctttt
    15241 tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt cccagaaaaa
    15301 gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac aaattgctta
    15361 ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag ctgctgctct
    15421 tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg acagcgattt
    15481 ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat tcttctaaaa
    15541 caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct gtgaaaaagt
    15601 cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc ttaaaggcat
    15661 gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg acaatgcaga
    15721 cagactgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga agtggttcgt
    15781 cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct ttaaacacca
    15841 aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca tctccgatca
    15901 aaggattgat ttgcttgtat ttattccaca tttcttgcgg tatcatgggt actcctttgt
    15961 aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat ctctaaatca
    16021 aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg attcattttt
    16081 tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt ctttcttgct
    16141 ttatcctgca tatctcttag catatctaac attattagac tttccagatc atgccattga
    16201 ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac tacaatcttt
    16261 gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa ttcaatcatc
    16321 gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg ttttaattgg
    16381 tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg ataaacttct
    16441 gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg cctggttcct
    16501 ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac taaacaattg
    16561 gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga gtacagggag
    16621 cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat gatgttttga
    16681 ttaagatctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa tagttgagga
    16741 taaatttttt caagaatttt ttcgccacta agggcaagtt gatttttcat agccattcac
    16801 ctcgtcttaa aagatacaat atcatatata attatatcaa aatttcctct agttcaaaag
    16861 cttcataagg ttcagataac tcatatccta aaaattctgc tacttttttg gaagcctcat
    16921 tatgagcatc ccaaagtgga aacatatctc tatttaaact ctctagaatc attgcagcac
    16981 caagcttttt agcaagtcca tttccttgtt cgtttggtct agttgcaact tccacttcaa
    17041 ctgctttacg gtaaactaac cctgaggaaa tcccagcaat cagttcatta tttttaagaa
    17101 tcacaaaacc aaatccacct tttaaaacaa aatcctgata ggactcaaaa tccccctgta
    17161 aatcctgtga ccattcttcc gtagaaaagc agttataaat atgattatca ataggcacaa
    17221 tattgtaacc ttcctctaaa tgagtaacta gattatttaa aaattcaact tgaaaatttg
    17281 ccttatcttt aaaagaatag cgagtaaaag aatttagccc cacttttcga tgcagaaaat
    17341 cttgccaatt agtattttct gaaataataa tcttataatc taaaccatat tttctaacaa
    17401 aatcttccca aaatctggaa tccaactccc ctgctaggta tagaaaattc ccaacatcat
    17461 aaaagcttgt tgtcctatca ttgtttcggt agacagttcc aatttgagat ttaagaccat
    17521 agagaaccat atttttcttc catgttttaa atagttccat tatccctcta cttcaccttc
    17581 caattcatgt aagaagtctt gtccagttct ggaaatccta ataattcaga cttaaccttc
    17641 aagactaatg gcgatgcatt ttcttctgta atctcttgaa tatccatcca aatatataca
    17701 agtgaatcat tcgcaccatc agacacagct tccgaagtcg taacttgagg tgcactctca
    17761 ttcatttcaa catcatacaa ggccatgaca tggtgaacca taaaattttt taactcttct
    17821 ctgacgaaaa catcgtagat tcgaggatta gagtagcttc taacagtaaa tcccgtctct
    17881 tccataactt ctctagtcag cgtttccgtc agtccttcac caagttgctg actgcctcca
    17941 ggtagatcat accgatgttg ataagggcct ctcgtttttt caatgcagag taacttccca
    18001 ttttctaagc aaacagcgta gactccaaag tgttttttga tttccatcca actcctccta
    18061 cttcaaagac cagccaccat ctattgtcaa gatttgtcct tgcatggcgc tcgcttttcc
    18121 acttgctaaa aaaagactaa gctctgctat ttcctctggc tcaatccagc gcttgattgg
    18181 ggtttcacta gccacccagt cagccaaacc acctggttca aaatccgcag cggtcatagc
    18241 tgtcttgact gctcctggag cgataccaaa gacctgaatc ccagcttcag catagtctag
    18301 agccaactgc ttggtgaagc cagccaaggc atgcttggat gaagtatagg cgtgaccacc
    18361 tccacctgct aggctagaag caatggaaca catattgatg atgattccct ttttattttc
    18421 cagcatttgt gtcaaataat accgagtcaa ctctgctgga ataatgtagt tgatttcaaa
    18481 aatctcttga atgtcctgcg ccgtttgttc caacagtggt ttgtaatcat ccaaaactcc
    18541 ggcagtatta cacaaaacat ccacctgagg gcaccagtca aaaataggtt ccaagtccaa
    18601 ggtcaaatct ctctgtaaaa agtgaaaatc accctctaag agtggctttt caccttggtc
    18661 aactccataa acttgatagc ccttctctaa aaagaggcga gcttgagcca atccgatccc
    18721 tgaacttact cctgtaatga gtacacgttt agtcatgcac ttctacccaa tccgttgcca
    18781 aaacatcaca aactgtcggg ctccacatgg aaaaaccttc tccttcgcca gaaacgttga
    18841 ttaggaaata aggtgtcatt tcaagtgcaa gcccgttttg ttcaatggtg tcaaaaagtt
    18901 ggacatagtt ttccgcacct ccccaaccag ttcgtacata ttttttctta tcctttaagc
    18961 caggtagaat ttcttcaaat gtcatgtttt tctcctttaa tgtcaataat tttccccttc
    19021 attataacaa aaaaaccgct ttaaaacggc tttttgactg tgatttattt acatcttctt
    19081 ctacttacgg caaattattc cctgcagcaa gataaatttc ataccattct tttcttgtta
    19141 agctaaagtt tgccgctcgg ctaacttctc tcaagtgctt aggatttgtt gtacctacga
    19201 ctgcctgcat ttttgctgga taacgcaata tccaagaaat ggcaatagtt gaagaggtta
    19261 ctccatattt aatagctaaa cgatcaagta cttgatttaa agcttgaaat ttctcatttc
    19321 caacaaagtt ccctttaaaa tacccgaatt gcaagacaga ccatgcttga atgaccacat
    19381 cgtgtaattt gcaatattca aaaatgctac catctcgcat agctgcttga ctatcttcca
    19441 tattaacatg aaaagctgat tcaaatcctg gagtaaaagc cgcactcaat tgtagctgat
    19501 taacagctaa cggctgcttg acatcttttt taagtaactc catcatcata ggattttgat
    19561 tagaaactcc aaaatctcga accttacctt gtttataaag gagatcaaag gcttctgcta
    19621 cttggtcaga ttctatcaaa gcatctggtc gatgaaggag caagctatct agatgatcaa
    19681 tcttcaatct ttgcaaaata ccgtctactg attttataat atagtcctta gaaaaatcaa
    19741 aataggtaaa ttcttcaatg cgaatgccac atttggactg aatccacatc ttttctctta
    19801 aatctggacg attttttagg acaagaccta acagttcttc acaacgacca cgaccataaa
    19861 tatcagccaa gtcgaaggca ttgattccaa cagaaagtgc tgtttctaca agctcttcaa
    19921 cttcttttac agacttatct tttattctca tcattccgag aacaatttct gataattctt
    19981 tgtcatcttg accaagagtt atgtatctca tcaaattttt ctcctttaat ttctaacatt
    20041 cttcccttca ttataacaaa aaaccgcttt gcaacggctt tttgactata cttcactcca
    20101 ttttatcttc ttaaacccac ggaacaagac aaaaattcca ataaagagga cagctaaagg
    20161 aataactttt gtaaggaaaa catttgaaat tcccatccac tcataataac ggagcagaga
    20221 acccaccaca agatgggcaa taatcatact gacaaatgga cgaaagaccg cttctttcca
    20281 attccaaata ccgataacta gcgaaatcgt aaagacagac aaactatccc agggagccgg
    20341 aatataaaag gctccttctt gtatgaagct tgccattcct acatatccta aaacaactag
    20401 aagaactata gtcccaacaa caatgtaagt gacaattttc attttaggag aatcttggac
    20461 taaacttctt cgtaaaattg tggccacaag tccaaatcca atcagaaaaa taagaagttg
    20521 ccctaaaaat gtgagcaaat tgactgttaa gagaggacct ttagaaaaat cacttagtag
    20581 ttgataataa cgtaataccg ccaggacaag aattggcgtc aaaagggact ctttgataga
    20641 actgcgaggt gctcccttga gaatctcttt cattattttt ttaggattct tacctagata
    20701 atcctctgca ctcatgccat ctcgttctgc ttctgagaaa tctagcatca tcaaatagat
    20761 ctgctctctg agatagtctt catcatagag aaatccagca agattaaaac tttcccacaa
    20821 ctcctcaaaa tacttttgat tctcctcaga aaactcatgt agcaaagcgc ttgtttcttc
    20881 gtaatacttc attttcttca tggtttaacc cccattctta atcccttcta ctttttgact
    20941 caaatcgtcc cattgttgcc aaaagactga gacacgctct tctccttctt tcattaatga
    21001 aaaatacttc cgatctggac catctggcga cgggcgcatg tcgcctctta tccattgatt
    21061 tttttctaac ttttgcaaca aaggataaat agttcctgga acgatagtat caaatccagc
    21121 ctctcgcaaa gtctgaacca actcataacc ataccgctct ttttgaccaa tcatatccaa
    21181 gacacaacct tcaagaacac cttttaatag ctgagtttct ttcatcactt ctcccttcta
    21241 atctattttg taatacctac tagtaacttc acctatagta tatcacttct acactagttt
    21301 gtaaagcata atagttaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcccta
    21361 ccgtaggtat ggttactgac ttcgtcagtt tcatctacaa cctcaaagca gtgctttgat
    21421 caacccgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa ataaaaaaac
    21481 agaactagtc tgaactagtc ctgtctactt ttacccaatc acacttccat ttggtacagc
    21541 tggatcaact gtgagaaggg ttaatttgcc atcatgttca gctgatagaa tcataccctg
    21601 gctgacatat tttttcatca ttttacgtgg tttgaggtta gcaacgattt gaactttctt
    21661 gccgaccaat tcttgttcat ttggatagta tttggcaatt cctgaaagaa tctgacgatc
    21721 ttctccataa ccagcatcca agcggaattg aagcaactta tctgaacctt ctactttaga
    21781 cacttctttg acttctgcga cacggatttc aaccttgtca aagtcttcaa acttgatttc
    21841 atccttgttt agtttgagct caacttcgtc cggattccat tctttttcga ctgctggttt
    21901 attgccttcc atttgttcct tgatataggc gatttcttct tccatattta gacgtggaaa
    21961 gataggtgtt cctttggcaa ctacagtcac atctgctggg aagtcagcca aactcaagtt
    22021 ttcaagacta gaaacttctt ccaaaccaag ttgagtcaaa actgcacgac tagtttccat
    22081 cataaatggt tcaatcaagt gagcaactac acgaatgctg gctgccaagt ggctcatgac
    22141 acttgccaat tggtcacgaa gagcttcatc cttggccaag acccatggtg ctgtctcatc
    22201 gatgtattta ttggtacgag agatcagagt ccagactgct tcaagcgcac gtggatagtc
    22261 aactgcttcc atgtgtgtat ggaagtctgc gattgattgt tctgcaacct cagcaagaac
    22321 atgatcaaat tcagtcacac cttctacata ggcagggatt tgtccatcaa agtacttatt
    22381 aatcatggaa accgtacggt taaggaggtt cccaaggtca ttagccaatt catagttgat
    22441 acggccgaca tagtcttcag gagtaaaggt tccgtctgaa ccaactggaa ggttacgcat
    22501 gaggtagtaa cgaagtgaat ctagtccata acgctctacc aacatttcag ggtaaacgac
    22561 attccctttt gacttagaca tttttccgtc tttcatgaca aaccaaccat gggcaatcaa
    22621 acgatcaggt aatttaacat ccaacatcat aagaaggatt ggccagtaga tagaatggaa
    22681 gcgaaggata tcttttccta ccatatggaa gactgttcca ttccagaact tgtcaaagtt
    22741 accatgttcg tcttgagcgt agccaagagc tgtcgcatag ttaagaaggg catcaatcca
    22801 aacgtagaca acgtgttttg gatttgatgg gacaggcact ccccatgtaa aggttgtacg
    22861 agataccgcc aaatcttcca aacctggctc gatgaagttg cgtagcattt cattaaggcg
    22921 accatctggc gtgataaatt caggatgagc tttgaaaaat tcgaccaaac ggtcttggta
    22981 tttgctaagg cgaaggaagt atgattcttc agaaacccat tcaacctcat gacctgatgg
    23041 agcaatacca ccagtcacat ttccagcttc atcacggaaa acttctgcca gctggctttc
    23101 tgtaaagaat tcttcgtctg atactgaata ccaaccagag tattcaccca agtagatatc
    23161 atcttgagca agtaagcgtt caaagacctg tgcgacaact ttttcatggt agtcatcagt
    23221 tgtacggata aatttatcgt atgagatatc tagtaattgc cagagttctt taactccaac
    23281 cgccattcca tcaacatagg tttgaggtgt aataccagct tcttccgctt tctgctggat
    23341 tttctgacca tgttcatcaa gacctgtcag ataaaataca tagtagccca tcaggcgttt
    23401 gtaacgtgct aggacatcac atgcgatagt tgtgtaggca gaaccgatat gaagtttccc
    23461 agatggatag taaatcggcg ttgtaatata aaaatttttt tcagacataa tttttccttt
    23521 ccaggcaaat gaaacctgtt tttctaacac ttcattatat cacattttta atgaatttcg
    23581 atagggaaat ccatacaaaa acaagataga cgagtgtcca tcttgttgat ctcattcata
    23641 acgaagggct tcaattggat caagtttcga tgccttgttg gctggcaaga ctccaaaaat
    23701 cataccaaca ctagccgaaa ctgcaagact aaatagggca actgggattg atactccaac
    23761 ttctatacct tctattaaac cttgcagtaa caaacctgct aaggcagtta aaccacttgc
    23821 aattgtcaag ccaattaagc cacctaacaa ggtcaaaatc atggattcaa tcaaaaactg
    23881 aattaaaata ttggcacgtg ttgcacccaa agccttacga agaccaatct cacgagtgcg
    23941 ctctgtcacc gaaaccagca tgatgttcat gacaccagtt cctccaacaa agagagaaat
    24001 ccctgcgatg gaactaataa tcgtcgtcat aaaactaaac gattgttgaa tttctgcaaa
    24061 tacaacggac tcatctgcca cctggtattc tccctgttgt aagcctgcaa gctctgtcat
    24121 ttttcgtgcc agttctggac ccagagttgg ggttaaactg gtatcattca ctcgaaagac
    24181 aatattagct atttcatcta cattaaaatt cgcagcaagg gagatattgg tagtaatagg
    24241 caagccacca aacccatata tttttgatct tttagcctcc ggactagtat aaaccccaat
    24301 gacccggtaa ctaaatccat tgacttctac aaccttgtta atagcctctt gaggagattc
    24361 aaataaacta atggacaatt cctcatctag caaaatgaca cttgcaaact ctttgaaatc
    24421 ttgctctctc agactacgac ctgcaataat ttcattctta acagcgtcca tgtaagttct
    24481 gtttccacct gtcaaattag cattctcaac ctttttatct tgataggtca agatggcatt
    24541 cgttgaattg gttacatagt aactatccac tcccttcagt ttagctgcct cttggaccca
    24601 ggattcttgc ggttttggcg gttcaacagg aacttcctct tcctttccag aaaccgtaaa
    24661 agctgattgt ttctgagtaa aagacccatc tttacttttt ttaggagaga aaaagacgct
    24721 aatatttttc tgagatttag tcatatcttt attgacttga cgagataggg aatcacccaa
    24781 agccataatc acaacaactg atgaaacacc gataataatc ccaatcatag taagcaaaga
    24841 acgcatcttg tgagccatga tagatgaaaa ggcaaatttc agattctgca tcttagtttt
    24901 cctcctttcc taactgagca ctgtcagacg aaatgacccc atcccgaatg acaatctgac
    24961 gtttggcata ggcagcaatc tcaggctcat gcgttaccat gataatggtt tttccttctt
    25021 tattcaaatc aaccaataat tgcataattt ggttacctgt tttggtatcc aaggctcctg
    25081 tcggttcatc cgctaggata atagaaggat tgtttaccaa ggcacgcgca atggctacac
    25141 gttgcttttg accaccagat aattctgaag gtaaatggtg actacgttct gtcaattcaa
    25201 ccttgtctaa atattcctca gccaacttgc gacgttttga agacgaaact cctgcgtaaa
    25261 tcaagggcaa ttctacattt tgcagagcat tgagcttcga tagaagaaag aactgctgaa
    25321 agacaaaacc gatttgttgg ttacggacct tagctagttg tttttcacca agcccagcca
    25381 cttcttgacc ttcaagataa tattctccac tggttggtgt atccaacatg ccaatcgtat
    25441 tcatcagagt ggacttacca gacccagatg gtcccatgat ggctacaaat tcaccctcat
    25501 tcacttctag attgatattt ttgagaacct gcagttcttg gtcaccatta cggtaacttc
    25561 tgaagatatt ttttagacta attagttgct tcatcagcct tcacctcttt tccttcttcc
    25621 aaggaagatg ttggattact gatgacctta gcaccgttcg ttaaaccaga agtgatttct
    25681 tgattttctg cgtcagcatt tcccaatgaa acctcaactt ttttagcctt ttgttgttca
    25741 tccacaatcc agacataatt tttactatca tccattacta gactgctaac aggaacaaga
    25801 atagccttag ttttgctttt aacctcaatg ttgacagaaa aaccttgttt caaatcacca
    25861 acctcgcctg tcacatcaat agtataaggg tatttagaac ctgtattatt cccggctgct
    25921 ggactagctg cttcaccatt gtttttagga tagtcagaaa tatagcttaa tttcccagtc
    25981 cattttttat caggatacac tttagaagta aagcttactt cttgacctac agaaaggttg
    26041 gctagattgt actcagacaa ttctcccttg acttgtaaat tttcattgct gacaatatga
    26101 accataactt gactcgcccc tgttggagat ttagaaacat tgctattgac ttcgactaca
    26161 gttccctcta gggtactgag aacagttgtt gcatccaatt gactttgagc cttgcttaat
    26221 tgcgctgcag catctgcacg cgcatcacgg gcatcaccca attgagcatc aatagaagca
    26281 acagaatttc cagccactgg agttgggctt tgcaccgttg catcttctcc tcctactggc
    26341 gctggtaact gtggagcctg agctgaagcg gcttcatttc gtgcttgatt gagttcattg
    26401 atatgacgat ctgccttagc tactgctcga ctagctgaat cataggccgc ctgcgcttct
    26461 gaactactgt acttgactaa agcctgccct tcgctgacct tatcgcccac agaaacaagg
    26521 atttcatcta aatcaccctt actagcatca aaataaacat attgttcatt ttttgctgtt
    26581 actgtccctg acaataaaac agaggatgcc acgcttcctt ccttggcaac aacaagatga
    26641 gtaggctcat cttttacagc agtctgagaa ggttgtctaa aaagtaaaat ccccccggca
    26701 cccaatacaa ctacactcgc agcaccgatt gctgcataca gttgccactt tttagcttta
    26761 ccattctttt tcttcataat gaaactcctt ttctttttta caatactttg ctattatacc
    26821 aaatttccct ccagcaaaca atgcagttca gatggaaata atggcagttc aggattaaac
    26881 aatcgttcgg aattttgctt ttctattgta ctagatatat aatacactat cttgacttat
    26941 ttggcaagct tttttgcaat tttttgtgcg tagcagattt ttgcaatcaa atcaaaaaaa
    27001 gaataaaata taactatcaa aaaagacgct ctactattta aaagattaca aaggagtttt
    27061 caatgagaga atatgatatc attgctatcg gtggaggtag cggaggaatc gctaccatga
    27121 accgtgctgg tgaacatgga gccaaagcag ccgttattga ggaaaagaaa ttaggtggaa
    27181 cctgtgtcaa cgtcggttgt gttcctaaaa aaatcatgtg gtacggggcg caaatcgctg
    27241 agactttcca tcaatttgga gaagactacg gctttaagac tactgatctt aactttgact
    27301 ttgcaaccct acgtcgcaat cgtgaagcct acattgatcg cgctcgttct tcttatgatg
    27361 gtagttttaa acgcaacggt gtagacttga ttgaaggtca tgctgaattt gtagattctc
    27421 atactgtaag cgtaaatggt gaactgattc gtgctaaaca tatcgtgatt gctacaggtg
    27481 cccatccaag tattcctaat attcctggtg ctgagctagg tggctcttct gatgatgtat
    27541 ttgcctggga agaacttcca gagtcagttg ccattctagg cgctggttat atcgccgttg
    27601 aattagctgg cgtactccac acttttggtg tcaagacaga tctctttgtt cgccgcgatc
    27661 gtcctttacg tggttttgat tcctacatcg ttgaaggttt ggtcaaggaa atggaaagaa
    27721 caaacttacc acttcacact cacaaagtcc ctgtcaagtt agaaaaaact actgacggca
    27781 ttaccattca tttcgaagat ggtactagtc acacagctag ccaagttatc tgggctacag
    27841 gtcgccgtcc aaacgttaag ggcttgcaac ttgaaaaagc tggagtgact ctgaacgaac
    27901 gtggctttat acaagtggat gaataccaaa ataccgtcgt tgagggaatc tatgctctag
    27961 gtgatgtaac aggcgagaaa gaactgactc cagttgcaat caaggctggg cgtaccctat
    28021 cagaacgtct ctttaacgga aaaactactt caaaaatgga ttactcaact attccaactg
    28081 ttgtcttttc acaccctgct atcggaactg ttggtttgac agaagagcaa gctattaaag
    28141 aatacggtca agaccaaatc aaggtttata aatcaagctt tgcatctatg tactctgctt
    28201 gcactcgcaa ccgtcaagaa actcgtttca aattgatcac agctggttca gaagaaaaag
    28261 ttgtcggact tcacggaatt ggctacggcg ttgatgaaat gattcaagga tttgctgttg
    28321 ctatcaaaat gggagcaacc aaggctgact ttgacgcaac tgtagcgatt cacccaactt
    28381 catctgaaga atttgtaacc atgcgttaat cgaaacaaaa gaagctgata taaatatgtc
    28441 tgcttctttt ttaatgattt tcgaatcaac aaaaaaatta tccaacttga ctagtcacga
    28501 aaatcggctg ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta
    28561 tatgagtata atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac
    28621 gtttatgcta tccctgctat tggggctgct ctcattgctg ctttggcaca aatcagtctt
    28681 ccaattggac ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc
    28741 tttagaccga gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt
    28801 cttcctgtct ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc
    28861 tatctttggt tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt
    28921 ggtgttgtta agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg
    28981 attctcagct tgcatttcct agctggaatg gcatttgaaa aaactcttgt tgtgggggtt
    29041 cttcccttta tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc
    29101 ctacttcaac gccttaaaaa tcaggcttac tttactaact aaaaaaggat accgagttat
    29161 catgactcaa tatccttttt ttattttgaa aacttatact caatgaaaat caaagagcaa
    29221 actaggaagc tagccgcagg ctgctcaaaa cactgttttg aggttgtgga tgaaactgac
    29281 gaagtcagta accatacata cggcaaggca aagctgatgc ggtttgaaga gattttcgaa
    29341 gagtattagt tgcctttaaa ggcatccacc atcgtttgaa attcttcatt tgagagagta
    29401 atccctttgc ccattttagt atggtctgga ctccaagcac gaatatcaaa ctttgcaggg
    29461 gcaccattaa agctcacacg gttaatttcc ttggtccaac ctttttcgtt ttcagaaaga
    29521 gtcaacaagt gctcttcgat ttcaaatgta aattctgcca ttttcttctc cttttttagt
    29581 ttcattagtt tattcgtaaa atcttgtaga ttttaggaaa attttatata atattgatat
    29641 aaaagaaggg aggctaatat gagacataaa ttccagcaag ttctaaataa aatacatgat
    29701 tttttaaatg gatatgacca acctgaccag actgaaacca actcccttac agccactatt
    29761 gaagaggcta tccagaaaca aaccgctgtt caccttatct tatctgagac aagctttaca
    29821 ggtgacatca tcaaatatga tcagcaaggc cagcaaatta tcgtgaaaaa tttttccaaa
    29881 aatgtgagcc ggattatccg tataagcgat attcaacgcc tgcgatttgt cccctcaact
    29941 gtccaaacag cccaaaaaaa tagatttaag aaagagtgag atgtagttgc ttcatcccac
    30001 tctttttctt agcgaatttg ttcaaaatgt aaatgaactg cgatatgatc tccataacca
    30061 cttctttcca agtcacgttg taaacgatag gaaatatagt gttctgcaat ggtaatgtaa
    30121 cctgcgccca ataaacgatg ttcaaccata gattgaatca tactgatagt cgcacgttcc
    30181 accttggctt cttgtaaatc caaaactacc ttcttagtga cttgagcaag attttgacgc
    30241 aaatcatctg tcaaaacata aacagtttgg gctgccttca agatggcttg gtaaatctta
    30301 tctggattaa attcagcaat ttcgccatta cgtttgatta cttgcatagg tttctccttt
    30361 attctttgtt ttctttgatt tctgccagca ttttttcttc ttctactgtc agttgataat
    30421 gttcaagtaa atccggtctg cgctcgtagg ttttctttaa actctcgtac aatcgccact
    30481 gacgaatctt ttcatgatgg ccactcatca atacatctgg cacgaccatg cctcgataat
    30541 catagggacg tgtgtactga ggatattcta aaagacctga agaaaaacta tcatcttggt
    30601 ggctagactc cttgccaatc acttctggaa tcaggcgaac tgtagcatca atcatggtca
    30661 tagctgccaa ttctccacca gtgaggacat agtcacctag ggaaatctca tctgttacca
    30721 aggtcttaat gcgctcatca taaccctcat agtgcccaca gataaagatt agctcttcct
    30781 cttgagccaa atcttcagca taagcctgat caaactgctt tccagcagga tcaaggagaa
    30841 taacgcgcgg atttttcttt tcaatagcat caaaggaatc gaaaataggt tgtgctctga
    30901 gcaacatgcc ctgaccgcct ccgtagggct catcatctac atgacgggcc ttttcagcat
    30961 tttctcgaaa attatgatac tggatatcca agagcccttt ttctcgagcc tttccaacga
    31021 ttgagtgctc cagtggagaa aacatctctg gaaagagggt taaaatatca atcttcatcg
    31081 tctaaccctt ctaagatttc cacatcgacc cgtttacttg gaatatcaac attgagaacc
    31141 actggtggga tataaggtaa aagcaaatca cgtttgcctt ttcgtttgac cacccagaca
    31201 tcattagcac ctggttgcag gatttccttg atggttccaa ccaagctatc accctcatag
    31261 acttccaaac cgataatctc gtgatagtaa aattcaccat cgtctaggtc attcaaatct
    31321 tcctcagcga ccttgagact gtatcccttg tacttttcga tagtattgat atggtacata
    31381 tctttgaatt taataatgtc aaagttcttc tgtttacggt ggctagcgat ggtcactgtt
    31441 tggacaaact gatctttttc atcaaacaaa gccagctcag ctcctttttt aaaccgttct
    31501 tctgcaaaat ccgtcacaga caagactcgc atctcaccct gtaatccctg cgtattaacg
    31561 attttcccaa cattaaagta gttcatcttg tctcctgtaa tctccttttt tccatcttat
    31621 tctgacaatt ctcgaataat agccgcaatt ttttccgatt ctgaccattg taaataatgg
    31681 tgattccctc ctaaaatgag tttagtattg gaagtccaat attctgattc tctgtactct
    31741 ttttctctat aagtctgaca aaaaataaat acagggacat gagattctat cgacaaattc
    31801 tcaaaatctt cctcagtaat ctctccagat atctgaaatt ctggatcttg attttccaac
    31861 tctaagcctt tttcttgcat taattcccag atttctttat tcgtttcagg actaaatgtt
    31921 gcttgagtta agttcttaaa ataaagttca ggtccatact cgtcaatcag cctcatctgc
    31981 tcttccattt ctggataagg attttctgaa aaatcagcaa acatgacttt tttagttgtc
    32041 ggttcaattg ctactaaagc ctgacactta attggtttct cgagtaattt gcaagctaaa
    32101 attccactcc aactatgtgc acaaagtata tattcagaaa tccctaattc ttcaagtact
    32161 tcataaaccg catctgcaag attatctaga ttttttccag cttggtcatg aatcgggctc
    32221 ctacctgtgt tcggaaaatc aattgtcaaa taaccaattg taggaggagg tttttcaagt
    32281 ataagtgaaa aattttcata acttggtagc aaacctgctc cgtttagaca aactagcact
    32341 ttcttttgct tttgataagt aacagagaga ctaccaattt ctgtagatac ttcaaacctc
    32401 ttcataaaga aatccactca ttctatataa tgaattatta aaaatcctta tcttttattt
    32461 tatcacgttc caaggatttt ctcaagttgg aggaagggga caacatctct actttccctt
    32521 caagaatcct tccaaatcat gtttatgttg gtaattaacg gctgcagttt tgtctttctc
    32581 aaagatggtt ctagttaggt caatatgctt gatagcagca atagcgacgg tgtagtgaat
    32641 gatatcagcc agttctctgg caagttcctc gttcgaatcc tatcccttct tttcgaccag
    32701 agcgcctatt caaaacctcg gctacttctc cgacttcctc cactaacttc ataaagagac
    32761 cttcatcagt ccgagactgc tgttaatgtt cgagtaagta gtcttggaat tgcctaaacg
    32821 ttcaatcttt tatagtatat tgaaactaga atagtacacc tttacttcta aaacattgtt
    32881 agaaatcgat ttgactgtcc tgatcgattt gtcctgttat tatttcattt tattatatct
    32941 tctattccac acaaaaaagc gagacatccg tcccgccctt tttatttttc gtcaataacg
    33001 attcttactt ttttgtattc agttgggaca gagtagacaa tcgttcttat cgcagaaata
    33061 gtgcgaccct tacgaccgat tacacgaccc acatcgcttt gatcaagatt caaatgatat
    33121 tccaaaaatt ctggtgtatc ctcaatcttg atagttaagg catctggttg tgaaattaag
    33181 ggtttcacaa tcgcaataat gagattttca atcgtatcca tctgtcaacc tactttaaac
    33241 ttattttgag aatttagaat cgtggaattt tttcaatacg ccttcttttg aaaggatgtt
    33301 acgtactgtg tctgaaggtt gagctccatt agccaaccat gcaagaacgc ggtcttcttt
    33361 caaagttact tggttttcag caacaagtgg gttgtaagtt ccaactgttt cgatgaaacg
    33421 tccgtcacgt ggtgaacgtg aatctgctac gttgatacgg tagaaaggtt ttttcttaga
    33481 acccatacga gtcaaacgga ttttaactgc catttttaaa gtctcatttc tttaattttt
    33541 tatttcggtg aaatagctga gctatttagc acatgttcta ttatagcaga tttctggcag
    33601 gtgtcaagaa aaaaacttga cagactataa atttcttaaa gtatttagaa atttgttaga
    33661 atcggaaata aatgtttgaa agatgctatc cgtgaatact attttagaaa aattttataa
    33721 agaacaccaa gtcaaaccct tcatatcgcc tgaacgagat ttggatactt ggctcctaag
    33781 tcccaagccc gttcccaagc gaaatatgga cttattagca gatgattcac tagcaggaga
    33841 tatcatttta ctatggagaa tccagtttgg tacttttacc actgaaacat gattttaaaa
    33901 actcccattc gaatatgatt caaaattcgc ttaaaatcaa tgttttccca ctttttcaaa
    33961 aaataaattt tcatctaatt taaataactt tcaattaagt gtgaattttg cttaaaatca
    34021 taaaaaaaca ccccatagtg tgaaccatga agtgttgtaa atgctgtgtt gtagctagtt
    34081 cttaacgttt agagaactgg ctagctttac gagctttctt aagatctggt tccctaaata
    34141 ctttgagtac acttatggca ttgatgcccc taaacatcta aaaactctgg tagaaaaagg
    34201 gtatgctctt gtcgaaactt cttttgactc acttgaccat ctaaataata ccatgaaaaa
    34261 gaatatcctg aagaagaagg gagttactag actttctaaa atgaaatctt gcgacctgga
    34321 tcaagccctt catgagcatt tttcagaaga agaattagct ggtcactttc atgtccttct
    34381 atggactttt ttacaatggc attgctatca cacccaatac ctatctaagc gcctggttcg
    34441 taaactttat tgcagctctt cctctaaatt tcctaattgt tgaaccaatt gcccgtttta
    34501 tactaagttc ttttcagaaa ccatttactg gggaagaagt tgaagatttt caagatgatg
    34561 atgaaatccc aactattatc taagccagtt ctgtaaacta ctaatatttg aaatccactt
    34621 ccttttaggg tacaatggta taaatgaatt tttgagagga acagaatgaa aaaactagca
    34681 acccttcttt tactgtctac tgtagcccta gctgggtgta gcagcgtcca acgcagtctg
    34741 cgtggtgatg attatgttga ttccagtctt gctgctgaag aaagttccaa agtagctgcc
    34801 caatctgcca aggagttaaa cgatgcttta acaaacgaaa acgccaattt cccacaacta
    34861 tctaaggaag ttgctgaaga tgaagccgaa gtgattctcc acacaagcca aggtgatatt
    34921 cgcattaaac tcttccctaa actcgctcct ctagcggttg aaaatttcct cactcacgcc
    34981 aaagaaggct actataacgg tattaccttc caccgtgtca tcgatggctt tatggtccaa
    35041 actggagatc caaaagggga cggtacaggt ggtcagtcca tctggcatga caaggataag
    35101 actaaagaca aaggaactgg tttcaagaac gagattactc cttatttgta taacatccgc
    35161 ggtgctcttg ctatggctaa tactggtcaa ccaaacacca atggcagcca gttcttcatc
    35221 aaccaaaact ctacagatac ctcttctaaa ctccctacaa gcaagtatcc acagaaaatt
    35281 atcgaagcct acaaagaagg tggaaaccct agtctagatg gcaaacaccc agtctttggt
    35341 caagtgattg acggtatgga tgttgtggat aagattgcta aagccgaaaa agatgaaaaa
    35401 gacaagccaa ctactgctat cacaatcgac agcatcgaag tggtgaaaga ctacgatttt
    35461 aaatcttaaa aaccaaaaaa atacagtatc cacattcggt actgtatttc ttttactctc
    35521 attcttaagt taaattatta aaatcccata tttggtctat ccagccttca taaaagtctg
    35581 gctcgtggca gaccataagg atagatcccc tatattcttt gagagcgcgt ttgagctcat
    35641 cctttgcatc cacatccaaa tggttggtcg gctcgtccag cactaaaacg ttgttttcac
    35701 gattcatcaa gagacagaaa cgaaccttgg cttgctctcc ccctgataat acttgaatct
    35761 ggctttcaat atgtttggtt gtcaaaccac aacgggcaag ggctgcacgg acttctgctt
    35821 gattaagggc aggaaaggca ttccagacag cttcaagagg agtttggcga ttaccgcctt
    35881 ctacttcctg ctcaaaataa ccaagttcta aataatctcc acgctccact tccccagcga
    35941 ttggcgagat aatgcccaag agactcttca agagagttgt ttttccaata ccattagcac
    36001 caataatcgc aaccttttga ttgcgttcga aggtaagatt taaaggctta gtaagaggac
    36061 ggtcgtaacc aatttgcaag ttcttggctt ggaagataaa gcgccctggt gtacgagctg
    36121 gtttgaaatc aaaggatggt tttggtttct cactttggag ttcgataata tccatcttat
    36181 ccaatttctt ttgacgagac atagccatat tacgagttgc aacacgggct ttattacgag
    36241 ccacaaagtc cttgaggtct gcaatctctt tctgctggcg ttcgtaggct gcctctagct
    36301 gagatttctt catagcataa acttcttgga actggtagta gtcaccagag taacgcgtca
    36361 gctgttgatt ttccacatga tagacaatat tgataacgtc attgaggaat ggaatatcgt
    36421 gcgaaatgag aacaaaggca ttctcatagt tttggagata gcgcttgagc caatcaatat
    36481 gctcagcatc caagtagttg gtcggctcgt ccaacagcaa aatatcaggc ttttcaagga
    36541 gaagttttgc caaaagcacc ttggttcttt gcccacctga caaagaagtt acatccgtat
    36601 ccatgccaaa gtccataaca ccaagagcac gcgctacttc gtcaatctta gcatccaagg
    36661 tatagaaatc acgactctcc agacggtctt gaagttctcc tacttcttcc atgagagcat
    36721 caacatccgc gccgtcttca gccattttca tatagaggtc attgatacga gcttcagctt
    36781 tgaaaagctc atcaaaagcc gtacggagaa catcacgcac cgactgtctt tcagcaagga
    36841 cagagtgctg atccaagtaa ccagccgtca catatttgga ccactcaacc tttccttcat
    36901 ctggcagcat tttaccagtc acgatactca taaaggttga ttttccttca ccattggcac
    36961 cgaccaggcc gatatgttct cccttgagga gacggaagga cacatcttca aaaattgcac
    37021 ggtcaccaaa accgtgactc agatttttaa cttctaaaat actcatttta attccttatc
    37081 ttgtttttat gtaatcgttt ataaaggagc caagccagat agccacccaa agtgttggtc
    37141 cacaaatcat caatctcaaa gacgcgattg aaatcaaaga aaaagtccaa gattaattgc
    37201 gtacactcga ttccaagact cacaagaaaa ctaaaaagaa gaaccttttt tgttttccgc
    37261 aaatttggaa atagataaag gagttggaaa atcagaggaa aaaacaagaa gacattgagg
    37321 atattttgta aaaaaatcca acataattgt ccaatgtcac tcacttcgcc cagtttccag
    37381 agagaattga aaggagtcaa aagaaaaacc aggcgtccaa gatgctgaat acctggagtt
    37441 cccacttcca cggtagcttg aggagtaaag caaaaataga caatgcatag gctataaaca
    37501 gccactccca atcttaagat taattctctt tttttagtca ttttacggat ttacctctgc
    37561 gactgccttc tggcggtcac gtttcattgt gttagagcgc aattgtccac aagctgcgtc
    37621 aatatctgta ccatactctt gacgaaccac acagttgacc ccttttttct taagcgtatc
    37681 atagaaagcc aacacgcgct ctttgggact acggctatat tggtcatgct cactaactgg
    37741 gttataagga atcaagttta cataagacaa tttcttgatg ttcttgagca attcagcaaa
    37801 ttccaaggct tgttctacac cgtcgttgac ttcattaagc atgatatatt caaaggttac
    37861 acgacggttt gttgtctcaa tgtagtattc aatagcagca aagagttttt caatcggaaa
    37921 ggcacggtta atcttcatga tacttgaacg aagttcattg ttgggtgcgt gaagagacac
    37981 tgcaagattg acctgaaccc cttcatcagc aaagttacga attttatgag ccaaaactga
    38041 ggttgaaacc gtgatgtgac gagcaccgat agccattcct ttatcatcat tgatagtaca
    38101 aacgaaattc aagacattgt tgtaattatc aaagggctca ccgattccca tgacaacgat
    38161 atggctgacg cgttcatcct gaccacgctc agcaaagtat ttctgaacca gcatgatttg
    38221 cgctacgatt tcaccgttat tgaggtcacg ttgcttctta atcaaaccag aggcacagaa
    38281 ggtacaaccg atattacagt cgacctgagt ggtcacacag acagataaac catagtgttg
    38341 acgcatgagt acagtttcaa ttaacatacc gtcaggcaat tcaaagagat atttgactgt
    38401 accatcagca gactcttgca caatacgttg tttcaaggga ttgaccacaa actggtcatt
    38461 gagcttagca atcaaatcct tggaaaggtt ggtcatttct tcaaatgact gcacacgttt
    38521 acggtagagc cattcccaga tttgatctgc acggaatttc ttttctccct gctccaatac
    38581 ccattcctgc atggtttgac gtgtcaaact atgaattgag ggtttcattt cttctcctta
    38641 ttctctactc acttctgacg aatgacaaaa tgacgttgtc ccttgtcctc tttctgagaa
    38701 tgctggtctt tctgacgacg tctatttttc ttatctgcat tcgactttcg tttagtttga
    38761 gtcggtttct ttccttttct agaaggtgtt tcttcttccg tcttacgcat tttcttgtca
    38821 aatgatgctc gcttaggggc ttcattttct aagacaaaat aggcacaacc ataactacaa
    38881 tactctaaaa ggtagtcttg taaacaactg attttttcaa gtttttcttc tgttcggtca
    38941 tccttgtaaa aacctcgtag gcgaagctgt tcgttgctcc agtcccccac gatataatca
    39001 aacttggtta atacttctga aaaacgctga ttaaaagtcg tcacatcaaa ggcatccttg
    39061 atattttcaa ccaaggaaaa agctatccct tccgtttcga ccttgtcccc gtgtaaatgg
    39121 aactccggac caggaaactt gttatagttg tataattcag gtgcaatttc ttttcgcata
    39181 gatatccttt ttccacgatt acttaatact ttattctacc ataatttcta gcagttagca
    39241 cgtttctcat aaaaatgaaa aaagtctgac gattttgtca gaccagaatc ttataaccta
    39301 aaaaagagaa gaacaattct tccctccaac tatcattatt tagcagctgc gtacaattca
    39361 tctactttat tccagttgat tactgaaaag aaagctttga tatagtcagg acgcacgttg
    39421 cggtatttca cgtagtaagc atgttcccaa acgtccaagc ccaagattgg ttttttacct
    39481 tctgagattg gtgtgtcttg gtttgctgtt gaagtcactt caagtttccc ttctttgttg
    39541 acaaccaacc atgcccaacc tgaaccaaaa cgagttgttg ctgctgcagt gaaggctgct
    39601 tggaattctt caaatgaacc aaatgttgca tcgattgctg ctgccagttc tgctgaagga
    39661 gctgttttct cgggagtcat caattcccag aaaagagcgt ggttcaagtg tccgccacca
    39721 ttgttgataa gtgcttgacg gatatcagct gggatagatt ctatatcagc aagcaaggct
    39781 tcaaggtctt caccgatttc agggtgtttt tctaaagctg cattggcatt gttgacataa
    39841 gtttgatggt gtttgtcatg gtgcaaatgc attgtttccg catcgatgta tggttccaaa
    39901 gcgtcgtatg catatggaag ttctggtaag ataatagcca tctgtaatac ctctttttct
    39961 ttctatatga aaatgataac gcaaacattc acttttttca agttttttgc ttatagataa
    40021 ggaaatcact gacatacttt ctaataaaat aagcaaatca gcaagaaacc cacgacaaga
    40081 taatcctgac gcgggttgta gtttcaacaa atgtcaattg acctgactag caatctgtaa
    40141 gagtgccttt tcaaaaagga aacctttttc ataaagacct gtcttaatct gatagtctgt
    40201 ctcaatcaaa taggaaatag cttgcttcag aaagctcaaa gaaagtcctc tcgaatctct
    40261 taatgcaaac ttgatttgat aaggatttgg gttacgtccc agataactac ctaaactact
    40321 tgcaatctgt gattctgttt ggccagactc cgccaaaatc ttcacctgag taaaagtccg
    40381 aaattgtccc agcatgactg caatcagttt gatttcatct tccccttgca aggtcaagtc
    40441 tctcaccaaa tcgcgcgcct gatccatctt tttagtcaga ataaactgag ttaaatcaaa
    40501 aatattgtcc tgcaaggtct tgggaattgc gttaacaata tcctcttcct caataacaga
    40561 attcgcctta taggactgta aaaagagaag atttttctgg atttcgctaa attgaaaccc
    40621 cgacttgatg aggagatttt caaaagaatg attggtaaac tgcagacctt gtttctgact
    40681 ccacttttgg aaatactggc gcaattcttg ttcttttact tctactgcat cgaagacctt
    40741 ggcatcacgc ttaagtaatt tgactaaccg tcttttgcta tccagctttc cttctgcaaa
    40801 gattatcaac ttggttgttg gagaaggatt gtcaaggtat tcctcaaatg acttaagctc
    40861 atcatctgtc aaaaagcgtt tcttagcagt cgtgatatcc ataaaataat ctaatatcac
    40921 gattttctca tccgcaaaga aaggaaggct gaccaactcc agttccacat ccttgtaaac
    40981 tacttctttc atatcaaagt aggcaaagtt gaggtcagca gaatcatacc caatctgttt
    41041 caacatttga ctcttcatca cttcaaactg accctgatct gtccctgtaa ataggctcag
    41101 gctcggtaaa tttgataaag tcaacttctg actttcttca atggctagca tcgtctctcc
    41161 tttcttcaga tttttcgatt taatttagtc aatatagcgc aatttcccac ggaaatcttc
    41221 taagctctcg tagccttttt ccaccatgat tgctttcagt tcattggtaa tgcggtcaaa
    41281 agcactgacg ccttctttgt gaagggtcgt tcccacctgc accatacttg ctccacagag
    41341 gatgtgttca aaggcatctc gaccagtcag aacgccacct gttccgataa tttggatttg
    41401 agggtttaaa cgttgataaa aggcgtgaac attggctaga gcagtcggtt tgatgtattc
    41461 tccaccaatt ccaccaaaac cattcttagg ccgaataacg acagattcgt cttctatata
    41521 gaggccgttt ccgatagagt taacgcagtt gacaaacttg agcggatatt tgttgaaaat
    41581 agctgccgct tgatcaaagt gaacaatatc aaaataaggt ggcaatttaa ttccaagagg
    41641 tttggtgaag taagcaaaca cttctgccaa aatccggtct gttgtctcaa aatcataggc
    41701 aatctgaggt ttacctggaa catttggaca ggaaagattt agctcagtca gaccacgaaa
    41761 atcactctct tggacttttt tcaaaatagt atgggtttcc tctggagaca taccgaccag
    41821 agataagaag aaagttcggt tcgactcttt ttcctgcaaa tccaaaagat aatccaaata
    41881 atagtctaag ccattatttg gcaagcccat agagttgatg gaaccaagtg gaacatcttg
    41941 gtagcgtggc tcaggattcc cctgacggaa gtccaaggtc gctgtcttag taacaaaggt
    42001 tcctgccgct gagtttttga cctcttctaa ctcctctatc gtcatacaag ccacacctgc
    42061 tgcattcatc aagcaattgt caaactcaaa accagcaatt tgtgttttcg ttgataccat
    42121 gattctaatc ctccagattt cttttattgc taatattata ccataatttt aattctaggt
    42181 ttactagatt ctgtggttct atctatttat ttggaaaaga aagtctagta cagaagtcat
    42241 gctatagaaa cagctagtgt attggaagtt tgaacaaggc ttgggtaaca gacttttgaa
    42301 tgaagtccaa gcaacaagga gaaatctcaa ccatgagtcc attccatgac tctgttgctc
    42361 tagaaaacct tgcaatagtc aagtgataac gaataaaact ttggattgaa atatccccat
    42421 gattatctat tacgaggaga aatctcaacc tttatcattt ttaaagaaat atagtaaaat
    42481 gaaacaagaa caggagaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    42541 agttgaagtg tactattcta gtttcaatct actatacatg taaatctcta ctttcgcaaa
    42601 atggattttc agaacagtat cccagtatag ttaaaaacta taaaaaagag aggacgttcc
    42661 cctcttaaaa tcttatttta ctgcttcttt caaagcatct accttatcca aacgttccca
    42721 tggaagatca atatctgtac gtcccatgtg accgtaagcc gatgtttgac ggtaaattgg
    42781 acgcttgagg tccagcattt ggataatccc tgcagggcga aggtcaaaga tttgacgagc
    42841 cgctttttca agttgacttt cagctactgt tcctgtaccg aaagtatcga tacgaacaga
    42901 aacaggttgc gcaacaccga tagcataggc caactgcact tctgccttct tagcaaggcc
    42961 tgctgcaacg atattcttgg caatatagcg agccgcataa gaggctgaac gatccacctt
    43021 agtcgcatct ttaccagaga aggcaccacc accatgacga gagtagccac cataagtatc
    43081 tacaataatc ttacgaccag tcaaacctga gtccccttga ggaccaccga ttacaaaacg
    43141 acctgtcgga ttgataaaga attttgtctt atcatcaaga taagaagatg gaataacttc
    43201 tttgatgacc ttgttaatca catcttgatg gatttgttca ttagtggcct ctggatcatg
    43261 ctgagtagaa ataacgactg tatctacacg taccggacgg tcattttcat cgtactcaac
    43321 tgtaacttgt gattttgcat ctggacggag atagctaatt tctccagact tacgaagttc
    43381 tgccagacga cgaaccaatt tatgactgag tgcaattggc aatggcatga gctcttctgt
    43441 ttcatctact gcaaatccaa acatgagccc ttggtcacct gctccaatca agtccagtgg
    43501 atcttgatca gcatttccac gaacctccaa ggcttcgtta acaccttgag cgatgtcagg
    43561 agattgttcc accaaagatg ggtgtactcc caccgtctca gcagaaaatc catattctgt
    43621 attggtataa ccaatctctg caatggtatc acgaaccaca cggttaatat ccacataggc
    43681 atttgtagaa atttcaccaa aaacgtggac agaaccagta tatacagctg tttcagcagc
    43741 aacgtgcgcc tctggatcct ttgctaaaat agcatccaaa atcgcatctg aaatttggtc
    43801 tgcaatctta tccggatgcc cctcagatac agattcagac gtgaataatt tacgttctga
    43861 cataaaaatg tcccccctta aaaaatattg ttatagagtt acaaagtact gataggaatt
    43921 tccattatct aagagttact agcttcagaa ataaaaacga tactttttta tttctgaagc
    43981 tagtaaggcg catagggtga ccgcagtatg gcggcaaccg tagaaagacg agcgacctcg
    44041 aagccgtcat tctttgcgaa gtgcaaacta ctgataggaa aactcttcgt aataaatacc
    44101 taccatctta tcgggactat ataactttat cattatacca tttttaatcg caatttgcag
    44161 tctttaatgt agtgtttcgg tttagatagt tcgttctcat aaataaaaaa gttggagctc
    44221 agtactccaa caatttctat taaaatgttt ggcgtttagc tttacgctct gcacgaccgc
    44281 gagcgcgatt ttcagcacgc ttggttttac ggcgcttttc atcaaccgcc cattgaattt
    44341 tcttcttata acccggtttg acttttttct ttttcttttt aaccaaacca atcatttcga
    44401 tatcaagttt atcttgtttt ttctcacggt tggcacgacg atcacggtca taggtatctt
    44461 gaaattcccc gtctttgacc atcttaggac taaacttgat tcccaatttc tccaactcac
    44521 ggatatccga gtcatcactt ggctgataaa gggtaatagc tgtacctggt aggccatttc
    44581 gtccagtacg accaacacgg tgaacaaaaa aagataagtc ttgcggaatg gcatcattga
    44641 tgacatggct gacaccttca atgtcaatcc cacgtgctgc caaatctgtt gcgacaatat
    44701 actcaaaatc cagatttttc acctgattca tgattcgctt gcgttcacga ggggcaatat
    44761 cgccatggat ttttgcaacc ttcaagcctt gagcagtcag atatgaatgc aattcatcag
    44821 cacgcgtttt agtgttaaca aaaatcattg ccaaatacgg ctgcatcaac tgagtcaact
    44881 ggtaaatttg agcattctta tcatgtccct tggtcgaaat caaccaatta tcaatggtgt
    44941 cagaaataac cgttttggtc ttaattttct ccataacagg atttgataag tattttttca
    45001 agaatggttg cagtttttgt gggatagtcg ctgagaagac catgaattgc aagtcttttg
    45061 gaagacagcc agcaatctta tcaacagttt ccaagaatcc catatccaag gtcatatctg
    45121 cttcatcaac aacaaatgtc ttggctttat gaatagctaa atcaccagat ttaaccaagt
    45181 cgtagatacg gcctggtgtt ccaataacaa tatgaggctg attgctttcc aatttctcaa
    45241 tctggcgagc cttatccgta ccacccacat aattaaccac acgaacttcg acatctgagt
    45301 gagctgaaat ctgacgcgct acttggtaaa tttgagtagc caactcacga ctcggtgcag
    45361 taatcactgc ttgtacacta tcgctagctt catctaattg ctggaaaatc ggtaacaaga
    45421 aagtatgagt cttacctgaa cctgtttttg attctcctac taggtcacga cctgccaaaa
    45481 caataggaat caacttgtct tgcacctctg ttggagttgt aaattttaac tccttcaagg
    45541 cttctctaat atagttttta aattgaaatt tcgtaaatga cataacatcc tcgattctat
    45601 ctatcttatc aattatacca tattttattc cattacagta gtctcactta tttaggctat
    45661 ttccagtagc ttctctagta agaaaaggct ggaattttat agttccaacc tcttttcagt
    45721 tattatttcc agtttaacat agcattcaag ccatagtgat cactcacttg tggactcttg
    45781 ttaccatcaa atacgacatg taaattttcc accgctaact ctttggtagt aaagacataa
    45841 tcgattcgaa ggggttcagt gttccctttc cagccatcaa tttcaggcgg aacagtatag
    45901 ctaccacttt tctcttgagc aacttcaaat gcgtcttgta agcctaatgg actagctaaa
    45961 atagcttggt aaccttcctg acctgctggg ttgttaaaat ctccagctag taaaagtggc
    46021 ttgttcaatt ttttcaagac agcctcaaat cgtgcccatt cttcttggaa acctttatcc
    46081 caccaagaga gatgaacact ggcaactgct agctccttgc catcgactac agtttcagct
    46141 agggcaacac ggcgagtatg atagtctgtt ggatcatcca catctgaaac caaaatttct
    46201 ctggcttcaa taggtgtttt agacaagata gccacacctt cgtggtagcg gtcatagccg
    46261 atatggttat aagcccaggt ccagtagtaa tttttccctt gctctaacaa cttttcaacc
    46321 aagagtctaa cataatggtc ttggtgaata gactcagctg ctggcaaagc ttgataaagg
    46381 tcattaacct ccacctctga cgaggtcatc tcctgattga tttcttgaaa acaaatcaaa
    46441 ttatagtcct tttcaagaat atcttcaagc aaaatctgga atttttcctc tgcttctttc
    46501 tccatccaac tgtgagtatt gagtgttaaa aatttcattc ttttctccca aaataagagg
    46561 ttggaataca gcttccaacc tcaagtatat tacaattcta ctttagcaac tgctgtttta
    46621 gctgcaagag aacctgtttt ttctaattta actgatttaa ttgcatcacc atttgtgaag
    46681 acaaccactg ttgaagtttc acgtcctgct gcacggatag catccaagtc agctgtgaca
    46741 aggagatctc ctgctgcaac tttttgtcct tcagcaacat gaactgtaaa tggtttacct
    46801 tcaagactta ctgtgtccaa accaatgtga accaatactt caagacctgc ttccgtcaca
    46861 ataccaaaag catgttttgt tgggaagatg cttgatacag tacctgaaac tggagataca
    46921 atgtttccat ttgcaggttc tactgcaaat ccatcaccca tcattttttg agcaaatact
    46981 ggatccttta cttgttccaa accaacaact tgaccgtctg ctactgagta aacttcctca
    47041 gtaagatctt tgaagtgaac agtgttttgt tgtgcttcag tcatttggct tggaagagtt
    47101 tcaggaatga tttcacctga atcaaggata tcttggatat cagatttcaa aatgtcagct
    47161 tttggaccgt agatagcttg aaccccttgt cctttcatga caagacccat agctccttct
    47221 gctttccatt gctctgcatt tcctacttta tctgcatctt taacagttac acgaagacga
    47281 gtcatacatg catcaacatc aacgatgttt acacgtccac caagaaggtt gataatgttt
    47341 acagcttgag agtctgctgc aactttcact tcgctgctgg tttcttctga accttcagca
    47401 gtttcgtagt ttccgttacg ccctggagtt gcgtagttga atttttgaat catgaagttt
    47461 gcgataaagt acatgattac agcaaagaga acagttaccc aaacgaagtt aacgatatcc
    47521 ataccaatac cagcactgat tgcaataggt gtacgagtca agaactcgat tgaaccgaat
    47581 gagtgcatac gtaggtttac gacgtcagcc atagcgaagg cagcaccttg aacaagtgag
    47641 taaacaagat acataggtgt tgcgatgaac atgaacatgt attcgattgg ttcagtaacc
    47701 cctgtcaaga atgttgcaag agctgttgca atcatcatac ctttgtattt atgtttcttg
    47761 tcagcatcaa cattacggta gatagcaaca atcacaccca tcaagatacc gaatgaaccg
    47821 atcatttgtc caactttgaa acgagctgga tgtactgtat ctaacaagtg ttgatattga
    47881 ctagcatcag tacctttaag gtttacaagg tctgttaccc atgcaagcca tagtgggtct
    47941 tgaccgaata cttgagtacc tttagctgca ccagttaaaa tgtcataagt accaccaaga
    48001 gctgtgtagt tcattgggat agtcaacatg tggtgaagac caaatggcaa gagcaaacgt
    48061 tccaaagtac catacaagaa tggtgcaaga attggagcag tttcttgtga gttggcaatc
    48121 cagataccga agttattgat acctgtttga actactggcc agaaagcagc aagtagaatt
    48181 gcagcgattg ctgaacgaag aataactaca aatggtacga aacgtttccc gttgaagaat
    48241 gaaagtgcat caggaagttt acggaagttg tagtatttgt tgtaagcagt tgcccctaca
    48301 aaacctgaga taatccctac gaataccccc atgttcaagg ctggagcttc aagaacactg
    48361 ataaagtaat cagcaacttt gattgaacca ccaaagaaag tagttaccat agcatctgga
    48421 tttttcaaca tatcgcctga tacaccaaag attgtaccag tgatacggtt aatcaagatg
    48481 aaggcaagac cagcggcgaa agcaccacca gcacgttctt tagcccagct tcctccaatg
    48541 gctagggcaa acaaaatgtg aaggttaccg ataacccccc aaccgatttg ctcaagaatt
    48601 ccacctgtga tgacaagtgg tgtaaaggtt gggttaatca tcacgataga cttaccgatt
    48661 gaaatcatca aaccagcagc cggcataacc gcgataacta ccatcaaagc cttaccgaat
    48721 ttttgccaaa attcgaaaga caagacattt ttgaatgtat ctttcatcat tcaaatctcc
    48781 tttattttta tttaggcaaa cgttttacga aaacgtttgc atcttctatg atttaattat
    48841 accactttaa ttttttttgt aaaggctttt ataaaaaaat tacacttttt tctaaaaaat
    48901 ttctagtgcg ccaaatttca agttcaaatt agccatcaag aagtcttctc tgggggactt
    48961 ctttggaagc tcttttcttc tacgcatctc ttttcaaaaa ctcttgtagc aaaaaaggag
    49021 attttacaat ctcctcataa aagcagctat tttacctaaa tcttcaagaa tcggcgcatg
    49081 gatattcctg atcccaatga accaatgaaa accccaatca caaatagtag ggcaatcatc
    49141 aacggactaa ataaatctgg actaatcatg gatagatttt gccctaccaa cgatttgttg
    49201 acagattggt aaacaatttg ataaacaata aagaccaaaa cagatggtgc gatagctccc
    49261 aataaaccga taaaggctcc ttctaacaag aacggtccac ggatataact gtttttagct
    49321 ccgaccaagc gcatgatttg aatttcgcga ctgcgggaaa taatggtaat acgaatggta
    49381 tttgaaatca agaaaactgc gataaaaatt aacaaagcag caatccctag tccccaaaca
    49441 cggataaatg aagctaactt gaagagtctt tctgtattgg caccgccatc ttgaacctca
    49501 gagacacctt caattttttt agcatcttcg gctatagttt ttacatcatt tggagtgttt
    49561 gcctctacaa tataggcatc atagagagga ttggcatctc cttcaaagat tttccagtta
    49621 tctcccatta tctcggttaa tttttcatat tgttcttctt tacttgaaaa ggtaacactt
    49681 ttaaccgtag acatgttctt caaagaatca tataccttgt ggtagtcatt atttgtaaca
    49741 gtttgacctt ctttttcaat tgtctgacta ttatcttcca catcctttcg gatataaact
    49801 actacacgga cattattttc aatatctgta gctagtttcg ctgtattgaa aataacagat
    49861 gcaaatattg ccaccaaggt caaagtaatc atgactgaac tgacagcagc tactgtcatc
    49921 caaccatttc gtttcaaact ttttaaggct tcaaataaat ggcgaaaaaa tctactaatc
    49981 atcgtatcca tactctcctt ttgattcgtc acgaacgaca cggccatttt caatggcaat
    50041 gacacggtgg cgcaaggtat ttacaatctg gctattatga gtcgccatca aaatagttgt
    50101 cccttgtagg ttaatccgtt ccaagagatt cataatttcc catgaattat ccggatccag
    50161 atttcctgtt ggctcatcag ctatcaatac tttgggatta tttacaattg cacgcgcaat
    50221 cgcaatccgc tgctgctccc cacctgagag ttcatttgga aaagaacgaa ccttatgctt
    50281 caatccaacc aagtccaaaa cttccatcac tcgtcttttg atattacggc gattttcccc
    50341 gattacttcc atagcgtaag caatattttc atagacagtt ttctttggta acagtttata
    50401 atcctggaag acaaccccaa cactacgacg tagaagcggg acatctttct ttttgatctt
    50461 aaccagatta aaaccagcaa ctgataggct tcctttatcg atttttactt cacgatacag
    50521 agaacgaata aaagttgact tccctgctcc tgaaggtcct acgatgtaag caaattcccc
    50581 cggttgaacg ctgaccgaaa caccgcgtag agcagtcgtt ccgttgtcgt attttttaac
    50641 gacatctctc atttcaataa ttgacatgtg agttcctttc tatcttagct aattcgccac
    50701 ttgagataag catcgataaa accatctagg tccccatcca taaccttatc tacctgagca
    50761 acctcaaagc tagttcggtg atcttttacc atagtataag gcgtgaagac ataagaacgg
    50821 atttggcttc cccaagtgat ctcctttttc tcacctttga gagaatctac ctccgcagcc
    50881 ttcttatctt gctccatttg atagagctta gcctgcaaca tcttcatggc acgatctcta
    50941 tttccatact gggtacgatc cactgttgat tggacaacaa ttccagttgg aatgtgggtt
    51001 aaacgtacac ctgttgaaac cttattgacg ttttgtccac cggcaccacc tgaacggaag
    51061 gtatccatct tgatatcatc ttcacggatt tccacttcaa tagtatcatc caattctggc
    51121 atcacttcta cagatgtgaa agaggtatgg cgacgtttgg cagagtcaaa tggtgagatt
    51181 cgcactaagc ggtgaacacc catttctgac ttgaggagac cataggcatt aggcccttca
    51241 aatgataaag ttaccgactt aataccagcc tcatcacctg cttggtaatc caacacttcc
    51301 actttaaagc ctttagcatt accataacga gtatacatac gaagcaacat atcaccccag
    51361 tcctgcgcct cagtaccacc agaacctgga tggatttcca agatggcatt gttgtggtca
    51421 taaggttctg acaagagtag agtcatctcg tagctggtca ttatcttatc aagttcggct
    51481 aactgcgcta ccagttcatc atgcactgac tcgtcttcag ccaaaaaatc caataaaatt
    51541 tcgacttcat cctgcaactc ttccatctta tggaaggtat tgtaagtgtt ttttaattca
    51601 ttcaattctt gcgacgtttt ttgggccgca atattatcgt tccaaaaatc aggttctgtc
    51661 atcttgtttt ccaagatggc aatctcttcc tctagccctt cgaggtcaaa gagaccccct
    51721 gaaagaagct aatttttcac gatttgcgtc aattttctga cgaattactg aaatgtccat
    51781 aaatactcct tttttacatt atttcattat agcatatttt atcatttctt tccatctttt
    51841 gctctaatcc ccttttcatg aaaaaagaag cctttgggct tcccttctta caagactttt
    51901 gctgaagtgc gagcgatttc ttccacttga ataccatttg cttcaaattt ttctttcaag
    51961 gctggtaaat caattgatcc atcgatttgc acttcgataa tgaccttacc atccttacgc
    52021 ggaatattga ctgtatggga tatattcaaa ttttcttcta caatcaaaga aataattttt
    52081 ccaagaacac caacttcatc ttctgtaaca aagcgtacac gaatcccttc ttcgccataa
    52141 cctgcaattt caagaaagga ttggaaaacg tcacggtcag taataactcc gtatacttga
    52201 tggttatcta cgacagggag aataccaatc ttatttttca acatcagata agttgcatct
    52261 tctagactag catagcctga gacagtgaca acatcgcgaa tcatgacatc ttttactttt
    52321 gtcttattca gaagataatt catctcatag atagaaagac ttgttgcttt agatggactt
    52381 gcttgtgcaa tggttccctc agtcaccaaa ccaactaatt gatcattttc gataacaggc
    52441 aagcggtgca attcttgctc tctcatcaaa tctgctgcat gagatactgt tgtatctgga
    52501 ctaatataaa ctaccttgcg ggtcataaaa tctttaactg ccatgagact tctccttttc
    52561 tattcttatc cctattatac aatctttttg caaatctatc aaacgcttac atttcttttt
    52621 caaaatttag aaaagtatga ataagctagc aaaaagagct ctaaaatcga gctctgtgaa
    52681 tgaaggtaag aaacttttca ttcgattttt tcaattatta gaaattaagc tttcaatgta
    52741 gatgcagatt tgtttgcaat ctcaatctac cgactaaaaa ggtcccccgg actatattga
    52801 tgattacttc gtaatctcca tctgccgact aaaacaatcc actggattgt tttagccacc
    52861 tagatatgct tttctgactt cttctgatga agcgagttct tttcctgttc ctgataggac
    52921 gattttccct gtttccaata catatcctcg gtcagagatt gcgagtgctt tattggcatt
    52981 ttgttcaatc aagaggacgg ttgttccttg cttctgaata tcttgaatga tatcaaaaat
    53041 ctcttggatg aagattgggg caagtcccat tgatggttca tctaaaagaa gaagttttgg
    53101 tgttgacata agagcgcgtc ccatggcaag catttgttgt tcccctcctg aaagagtagc
    53161 tgcatcttgg ttcttccgtt cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt
    53221 agcttgattt tcttcacgat ttttctttaa gaaagctccc atttcaagat tttccataac
    53281 agtcaagcca ggaaagacgt ggcgtccttc tggaacttgt gaaagaccac ctgccacgat
    53341 tttctgagct ggcatttttt ggatttcttg acctaaaaat tcaatctttc ctgaacttgg
    53401 tcgaaccaaa cctgacaagg tgcgaagaat agttgtctta cctgcaccgt tggcaccgat
    53461 aagggaaaca acttctcctt cattaacttc aaagcttaca tcacggactg cttggatcat
    53521 accgtaatgc acagaaagat tttcaacttt taacatagac attaggcttc acctcctaga
    53581 taagcttcga taacgcgttt attggtctta atttcgtctg gagttccttg agcaattaaa
    53641 cggccatatt caagtacgta gatacgttct gttacttcca tgaccagatt catatcgtgt
    53701 tcaatcaaca tgattgtaat cttaaattca tctttgatac gacgaattaa ctcagtcaat
    53761 tcggctgttt cctgtgggtt catacctgct gctggttcat ctaagaagag aattttaggt
    53821 tccgtagcaa gggcacgaac aatttccaaa cgacgttgtt gtccgtagga aagattttta
    53881 gcaagagtct ctgcatcacc atctaaatca aagattttca acaattccaa agctttagcc
    53941 tttaattctt tttcactctt gtaaaaaact ggtaagcgta agaaactagt aaaaacatgc
    54001 tgtttgtgat ggtttccaaa agcaatcaaa acattgtcta aaactgttaa atctttaaaa
    54061 agacggatat tttggaaagt acgtccaagt cccaaagagg caatcttata aggtgatttc
    54121 ccattcaaaa ggtgaccatc tagggttact gttccctcgc ttggttcata aacaccggtc
    54181 aaaaggttga aaagggtggt tttcccagct ccgtttggac cgattaatcc aaccagttcc
    54241 ccttcgttca attcaagagt cacatctcca acagctgtta gaccaccaaa atgtttggtt
    54301 aactgtttta cttcaagtaa tgccattagt tttgttcctc cttcttagat tttttaaaga
    54361 aacgtgatag gctcagttcc cacgttccaa ggagtccacc tggtctgaaa atcattacca
    54421 ataccaaggc caaagcgtaa ataatcatac gcacactagc aacatcttgg agaagcatat
    54481 tcaaaattcc cagaacaata gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa
    54541 atacaacaat aatcaaaacg ttgattgagt tgatgaaggt gtaatctttc ggtacaacag
    54601 acccgataaa tcctgcctga agtgacccag caatacttgc agtaatggca ccaaagacaa
    54661 aagcgatgat tttaatttta gtcgtattaa ccccaactga ctcagcagcg atttcatctt
    54721 cacgaacaga gagggttgaa cgaccaattg ggctacgcaa gaagttcaag gttgcaatgg
    54781 ttgtaatcac gacaaagaag taaaccattt gccaagttgt aaagttagga atccctaaga
    54841 tacctgccgc accatttgta aggcttccac cattgatgat aaagatgcgg ataatttcag
    54901 aaacacctag agttgctacc gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga
    54961 caagtaaggc aactgctcct gaaagcaaag cccctacaag catagctcca aagaaggcac
    55021 cgtaggttgg taatttagaa ccaataatag ctgctgcata ggcaccaatc gccatgaaac
    55081 cagcatgacc aagtgaaaat tgtcctgaaa aaccaacgat taagttgaga ccaacagcca
    55141 aaataatatt aattccaatt tgctgtaaaa tctgtacata gaatagatta agtactccga
    55201 ctgaaaccag tacactaatc aagctatagc cagctaacaa aaggagtaac catagaatat
    55261 taacttttaa attttccttc atcgtttaca ccttctcttt cacattctta ccaaggatac
    55321 cagctgggcg gacaatcaag atcaacaaca agattccata aacaatggca tcacggaaat
    55381 ctgacatccc aaaggcagtc gcaaaggttt ccaatagacc aatcacaaag ccaccaagag
    55441 ccgcaccagg aataattccg ataccaccaa gtactgcggc aacgaaagat ttaagacctg
    55501 gagtaacccc catcaaaggc tcaagagagt tataataaag agcaatcaga acaccagccg
    55561 cacccgcaag agcagaaccc aaagcgaagg taaagctaat cgtacggttt acattgatcc
    55621 ccatcaattg cgccgcgtcg ctatctactg atactgcacg catggctttc cccatcttag
    55681 tcttttggac aatgacttgt aacaaaatca tcaaaatcaa ggaaatagcc aaaatcatta
    55741 actgcacatt tgttaagcta attggtccca aatcatatcg aactgtttga atcgcttgag
    55801 ggaaggcacg ggtattggca ccaaccagat agaccattcc atactccaat aggaaagaaa
    55861 ccccaatagc cgtaatcaaa acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa
    55921 gaaactcaat cacgacacca agaatagctg tcgctagcat agctacaata agcgctacaa
    55981 agaaattcat ttggaaagaa ttgatcaaga aataaccgat aaaggctccc atcatataaa
    56041 tatcaccatg ggcgaagttg atgagcttga taattccgta aaccatggta tatcctaggg
    56101 ctaacagcgc gtaaacacta cctagaatca aaccatttac gagttgttgg agcataagat
    56161 tcactctttc tatttataat tccgaggggt ttccctcact ttttgatagg ttcttatact
    56221 caatgaaaat caaagagcaa actaggaaac tagccac
//
LOCUS       DAVDFK010000012        55869 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.12, whole genome shotgun sequence.
ACCESSION   DAVDFK010000012 DAVDFK010000000
VERSION     DAVDFK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.12"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..463)
                     /locus_tag="VUR04_000864"
     CDS             complement(<1..463)
                     /locus_tag="VUR04_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5340788.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDITHQLAISTSTVIRKLNDFHFEHDFSRLPKIM"
     gene            1013..1531
                     /locus_tag="VUR04_000865"
     CDS             1013..1531
                     /locus_tag="VUR04_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET5340789.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            1661..2167
                     /locus_tag="VUR04_000866"
     CDS             1661..2167
                     /locus_tag="VUR04_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET5340790.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            2167..2337
                     /locus_tag="VUR04_000867"
     CDS             2167..2337
                     /locus_tag="VUR04_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340791.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            2369..3601
                     /gene="clpX"
                     /locus_tag="VUR04_000868"
     CDS             2369..3601
                     /gene="clpX"
                     /locus_tag="VUR04_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET5340792.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            3610..4197
                     /locus_tag="VUR04_000869"
     CDS             3610..4197
                     /locus_tag="VUR04_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET5340793.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            4208..4588
                     /locus_tag="VUR04_000870"
     CDS             4208..4588
                     /locus_tag="VUR04_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET5340794.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            4640..5530
                     /gene="rapZ"
                     /locus_tag="VUR04_000871"
     CDS             4640..5530
                     /gene="rapZ"
                     /locus_tag="VUR04_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET5340795.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            5527..6504
                     /locus_tag="VUR04_000872"
     CDS             5527..6504
                     /locus_tag="VUR04_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET5340796.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            6501..7412
                     /gene="whiA"
                     /locus_tag="VUR04_000873"
     CDS             6501..7412
                     /gene="whiA"
                     /locus_tag="VUR04_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET5340797.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(7446..8411)
                     /locus_tag="VUR04_000874"
     CDS             complement(7446..8411)
                     /locus_tag="VUR04_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET5340798.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            8547..9404
                     /locus_tag="VUR04_000875"
     CDS             8547..9404
                     /locus_tag="VUR04_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET5340799.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            9391..10170
                     /locus_tag="VUR04_000876"
     CDS             9391..10170
                     /locus_tag="VUR04_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET5340800.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            10194..11546
                     /locus_tag="VUR04_000877"
     CDS             10194..11546
                     /locus_tag="VUR04_000877"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET5340801.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            11620..11994
                     /locus_tag="VUR04_000878"
     CDS             11620..11994
                     /locus_tag="VUR04_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET5340802.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            11996..12844
                     /locus_tag="VUR04_000879"
     CDS             11996..12844
                     /locus_tag="VUR04_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5340803.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            13110..13877
                     /locus_tag="VUR04_000880"
     CDS             13110..13877
                     /locus_tag="VUR04_000880"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET5340804.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            13889..15073
                     /locus_tag="VUR04_000881"
     CDS             13889..15073
                     /locus_tag="VUR04_000881"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET5340805.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            15070..16941
                     /locus_tag="VUR04_000882"
     CDS             15070..16941
                     /locus_tag="VUR04_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5340806.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIDTLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(17084..18268)
                     /gene="mntE"
                     /locus_tag="VUR04_000883"
     CDS             complement(17084..18268)
                     /gene="mntE"
                     /locus_tag="VUR04_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET5340807.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            18572..21268
                     /locus_tag="VUR04_000884"
     CDS             18572..21268
                     /locus_tag="VUR04_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET5340808.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            21281..22072
                     /gene="yghU"
                     /locus_tag="VUR04_000885"
     CDS             21281..22072
                     /gene="yghU"
                     /locus_tag="VUR04_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET5340809.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTVGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            22188..22598
                     /locus_tag="VUR04_000886"
     CDS             22188..22598
                     /locus_tag="VUR04_000886"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET5340810.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANHDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            22610..24205
                     /locus_tag="VUR04_000887"
     CDS             22610..24205
                     /locus_tag="VUR04_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340811.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            24272..24436
                     /locus_tag="VUR04_000888"
     CDS             24272..24436
                     /locus_tag="VUR04_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET5340812.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            24515..25243
                     /gene="yaaA"
                     /locus_tag="VUR04_000889"
     CDS             24515..25243
                     /gene="yaaA"
                     /locus_tag="VUR04_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET5340813.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(25521..26069)
                     /locus_tag="VUR04_000890"
     CDS             complement(25521..26069)
                     /locus_tag="VUR04_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5340814.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            26390..26878
                     /locus_tag="VUR04_000891"
     CDS             26390..26878
                     /locus_tag="VUR04_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET5340815.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSNFYLVDFETGALVNKE
                     GL"
     gene            26875..28062
                     /locus_tag="VUR04_000892"
     CDS             26875..28062
                     /locus_tag="VUR04_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5340816.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMVEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTCEELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            28055..28420
                     /locus_tag="VUR04_000893"
     CDS             28055..28420
                     /locus_tag="VUR04_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5340817.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSERLIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            28436..29782
                     /gene="asnS"
                     /locus_tag="VUR04_000894"
     CDS             28436..29782
                     /gene="asnS"
                     /locus_tag="VUR04_000894"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET5340818.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            29935..30225
                     /locus_tag="VUR04_000895"
     CDS             29935..30225
                     /locus_tag="VUR04_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET5340819.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            30237..30707
                     /gene="ssbA"
                     /locus_tag="VUR04_000896"
     CDS             30237..30707
                     /gene="ssbA"
                     /locus_tag="VUR04_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET5340820.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVRESHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            30739..30978
                     /locus_tag="VUR04_000897"
     CDS             30739..30978
                     /locus_tag="VUR04_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET5340821.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            31273..32673
                     /locus_tag="VUR04_000898"
     CDS             31273..32673
                     /locus_tag="VUR04_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET5340822.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            32675..33034
                     /locus_tag="VUR04_000899"
     CDS             32675..33034
                     /locus_tag="VUR04_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET5340823.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            33088..33837
                     /locus_tag="VUR04_000900"
     CDS             33088..33837
                     /locus_tag="VUR04_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET5340824.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            33827..34126
                     /locus_tag="VUR04_000901"
     CDS             33827..34126
                     /locus_tag="VUR04_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET5340825.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            34197..35132
                     /locus_tag="VUR04_000902"
     CDS             34197..35132
                     /locus_tag="VUR04_000902"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET5340826.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            35219..35731
                     /locus_tag="VUR04_000903"
     CDS             35219..35731
                     /locus_tag="VUR04_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET5340827.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            35756..36364
                     /locus_tag="VUR04_000904"
     CDS             35756..36364
                     /locus_tag="VUR04_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HET5340828.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            36465..36662
                     /locus_tag="VUR04_000905"
     CDS             36465..36662
                     /locus_tag="VUR04_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET5340829.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(36705..38150)
                     /locus_tag="VUR04_000906"
     CDS             complement(36705..38150)
                     /locus_tag="VUR04_000906"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET5340830.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLVWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            38256..39878
                     /locus_tag="VUR04_000907"
     CDS             38256..39878
                     /locus_tag="VUR04_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET5340831.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILIGLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            40082..42040
                     /locus_tag="VUR04_000908"
     CDS             40082..42040
                     /locus_tag="VUR04_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5340832.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            42212..42445
                     /locus_tag="VUR04_000909"
     CDS             42212..42445
                     /locus_tag="VUR04_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HET5340833.1"
                     /translation="MKLKLLRVDTKVIMGSFLFVLSSLLALLLPLILKGLIDGSSIEN
                     IGFKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            42451..43893
                     /locus_tag="VUR04_000910"
     CDS             42451..43893
                     /locus_tag="VUR04_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340834.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGRGLNFNHVYFGYDENRPVLKDIICSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGQSQRLQIARA
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            44051..45145
                     /locus_tag="VUR04_000911"
     CDS             44051..45145
                     /locus_tag="VUR04_000911"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET5340835.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            45153..46319
                     /locus_tag="VUR04_000912"
     CDS             45153..46319
                     /locus_tag="VUR04_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5340836.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHSRINIAMPKSLLQEVCQRIVATFAKR"
     gene            46412..49510
                     /locus_tag="VUR04_000913"
     CDS             46412..49510
                     /locus_tag="VUR04_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5340837.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQEMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            49558..50175
                     /locus_tag="VUR04_000914"
     CDS             49558..50175
                     /locus_tag="VUR04_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET5340838.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            50186..51520
                     /locus_tag="VUR04_000915"
     CDS             50186..51520
                     /locus_tag="VUR04_000915"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET5340839.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            51530..51994
                     /locus_tag="VUR04_000916"
     CDS             51530..51994
                     /locus_tag="VUR04_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340840.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            51991..52485
                     /locus_tag="VUR04_000917"
     CDS             51991..52485
                     /locus_tag="VUR04_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340841.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            52566..54221
                     /gene="mltG"
                     /locus_tag="VUR04_000918"
     CDS             52566..54221
                     /gene="mltG"
                     /locus_tag="VUR04_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET5340842.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            54292..54774
                     /gene="greA"
                     /locus_tag="VUR04_000919"
     CDS             54292..54774
                     /gene="greA"
                     /locus_tag="VUR04_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET5340843.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            55102..55500
                     /locus_tag="VUR04_000920"
     CDS             55102..55500
                     /locus_tag="VUR04_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340844.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT        16491 a        10489 c        12741 g        16148 t
ORIGIN      
        1 acataatctt tggaagccga gaaaaatcat gctcaaagtg aaagtcattg agcttgcgaa
       61 taacagttga agttgaaatg gccagctgat gggtaatatc agtcatagaa attttttcaa
      121 ttaacttttg agcaattttt tggttgatga tacgagggat ttggtgattt ttctttacca
      181 ggggagtctc agcaaccatc atttttgaac agtgatagca cttgaaacgg cgttttctaa
      241 ggagaattct agaaggcata ccagttgttt cgaggtaagg gattttagaa ggtttttgaa
      301 agtcatattt cttcatttga cttccgcact cagggcaaga tggggcgtcg tagtccagtt
      361 tggcgatgat ttccttgtgt gtatccttat tgatgatgtc taaaatctgg atatttgggt
      421 ctttaatatc gagcagtttt gtgataaaat gtaattgttc catatgaatc tttctaatga
      481 tggttttgtc gcttttcatt ataggtcata tgggactttt tttctacaac aaaataggct
      541 ccataatatc tataagggat ttacccacta caaatattat agagccgtaa attcaagatc
      601 ttgctcggaa atgaagctta tatagtagat tgaatataga caaagacctt gtgattggta
      661 aaacatttta gaaattcatt tacctttcct aatcgacttg gtttcatctt atttcaatct
      721 attatagtat tggggaattt cttcaaacca catcagcttg gtcagttcta cctgcgacct
      781 caaaacttgt gctttggtca agctgggttt agtttcctag tttgctgatg gatttccatt
      841 gactataagc atccaaccct cttttttgtc ttctaaagaa ttcttaaatt atcagtctat
      901 tgcaactttt ctcatataag ttctttgtct tgctattggt tttccttagt agtatactaa
      961 ggtagtaatc attaagaagt ggttacaaaa aataatgaat gaggtaaaga aaatggtaga
     1021 attgaaaaaa gaagcagtaa aagacgtaac atcattgaca aaagcagcgc cagtagcatt
     1081 ggcaaaaaca aaggaagtct tgaaccaagc tgttgctgat ttgtatgtag ctcacgttgc
     1141 tttgcaccaa gtgcactggt atatgcatgg tcgtggtttc cttgtatggc atccaaaaat
     1201 ggatgagtac atggaagctc ttgacggtca attggatgaa atcagcgaac gcttgattac
     1261 actcggtgga agcccattct ctacattgac agagttcctt caaaatagtg aaatcgaaga
     1321 agaagctggt gaataccgta atgttgaaga aagcttggaa cgtgttcttg ttatctaccg
     1381 ttacttgtca gaacttttcc aaaaaggttt ggatgtcact gatgaagaag gtgacgatgt
     1441 gacaaacggt atctttgcag gcgctaaaac tgaaacagat aaaacaattt ggatgcttgc
     1501 agccgaactt ggacaagcac ctggtttgta agaaataagg aaacatagat aaatctgtag
     1561 gaaatttctt acagattttt tctattttgt aagctattcc aaaccagtct ttttttgagt
     1621 tttttgataa aatagtacta tcagtgaaaa ggatggaagc atgactaaga aaatcgtagc
     1681 tatttgggcc caggatgaag agggtgtgat tggtaaggaa aatcgtctgc cttggcattt
     1741 gccagcagaa ttgcagcact ttaaagaaac aactctgaat catgctatct tgatggggcg
     1801 tgtgaccttt gatgggatgg ggcgtcgctt gcttccaaaa cgggaaacct tgattttgac
     1861 gcgtaatccg gaagaaaaga tagatggggt tgctactttt caggacgtcc agtctgttct
     1921 tgactggtat caggctcaag aaaagaatct ctacattatc ggtgggaagc aaatttttca
     1981 ggcttttgaa ccttaccttg atgaagtgat tgtcactcac attcatgctc gggtggaagg
     2041 agatacctat ttccctgaag aacttgactt gtctcttttt gagacagttt caagcaaatt
     2101 ttacgccaaa gatgagaaga atccttatga ttttaccatc caataccgca agagaaagga
     2161 agtctaatgg aacggagttt atttggtcta ttcacggctt ttctgtgttt catctgcttt
     2221 ctggcaggag cacaagcttt tcgtaaaaag cgttacgggc tttctatcct cctttggtta
     2281 aatgccttta ccaatctggt caatagtatt catgcttttt acatgacctt attttagata
     2341 gaatgacagt atagaatgga aggaaatcat gtctacaaat agaaaaaatg atatgatggt
     2401 ttattgctca ttttgtggca aaaaccaaga agaagtacaa aaaataattg ctggcaacaa
     2461 tgcttttatt tgtaatgaat gcgtggagtt agctcaggaa atcattcgag aagaattggt
     2521 tgaggaagtc ttggcagact tgtctgaggt gccaaaacca attgaactcc tccatatctt
     2581 gaaccactat gtaattggtc aagatcgtgc caagcgtgcc ttggcagtgg cggtttataa
     2641 ccactacaaa cgcatcaatt tccacgatac acgcgaagag tcagaagatg tggatttgca
     2701 gaagtcaaac attttgatga ttggcccaac tggttcaggg aaaactttcc ttgcccagac
     2761 cttggctaag agcttgaatg taccttttgc tattgcggat gcgacagctc tgacggaggc
     2821 tggttatgtg ggtgaggatg tggaaaatat cctcctcaaa ctcttgcagg ttgctgactt
     2881 taacatcgaa cgtgcagagc gtggcattat ctatgtggat gaaattgaca agattgccaa
     2941 gaagagtgag aatgtgtcta tcacacgtga tgtttctggt gaaggggtgc aacaagccct
     3001 tctcaagatt atcgagggaa ctgttgctag cgtaccgcct caaggtggac gcaaacatcc
     3061 acaacaagag atgattcaag tggatacaaa aaatatcctc ttcatcgtgg gtggtgcttt
     3121 tgatggtatt gaagaaattg tcaaacaacg tctgggtgaa aaagtcatcg gatttggtca
     3181 aaacaataag gcgattgacg aaaacagctc atacatgcaa gaaatcatcg ctgaagacat
     3241 tcaaaaattt ggtattatcc ctgagttgat tggacgcttg cctgtttttg cggctcttga
     3301 gcaattgacc gttgatgact tggttcgcat cttgaaagag ccaagaaatg ccttggtgaa
     3361 acaataccaa accttgcttt cttatgatga tgttgagttg gaatttgacg acgaagccct
     3421 tcaagagatt gctaataaag caatcgaacg gaagacaggg gcgcgtggac ttcgctccat
     3481 catcgaagaa accatgctag atgttatgtt tgaggtgccg agtcaggaaa atgtgaaatt
     3541 ggttcgcatc actaaagaaa ctgtcgatgg aacggataaa ccgatcctag aaacagccta
     3601 gaggtgacta tggaacttaa tacacacaat gctgaaatct tgctcagtgc agctaataag
     3661 tcccactatc cgcaggatga actgccagag attgccctag cagggcgttc aaatgttggt
     3721 aaatccagct ttatcaacac tatgttgaac cgtaagaatc tcgctcgtac atcaggaaaa
     3781 cctggtaaaa cccagctcct gaactttttt aacattgatg acaagatgcg ctttgtggat
     3841 gtgcctggtt atggctatgc tcgtgtttct aaaaaggaac gtgaaaagtg ggggtgcatg
     3901 attgaggagt acttaacgac tcgggaaaat ctccgtgcgg ttgtcagtct agttgacctt
     3961 cgtcatgacc cgtcagcaga tgatgtgcag atgtacgaat ttctcaagta ttatgagatt
     4021 ccagtcatca ttgtggcgac caaggcggac aagattcctc gtggtaaatg gaacaagcat
     4081 gaatcagcaa tcaaaaagaa attaaacttt gacccaagtg acgatttcat tctcttttca
     4141 tctgtcagca aggcagggat ggatgaggct tgggatgcaa tcttagaaaa attgtgagga
     4201 aaagaaaatg gcaaaaacaa ttcatacaga taaggcccca aaggctatcg gaccctatgt
     4261 tcaaggaaaa atcgttggca accttttgtt tgctagcggt caagttcccc tatcccctga
     4321 aactggggaa attgtaggag agaatatcca agaacagaca gagcaagtct tgaaaaacat
     4381 cggtgctatt ttggcagaag caggaacaga ctttgaccat gttgtcaaaa caacttgctt
     4441 cttgagcgat atgaacgact ttgttccttt taatgaggtt taccaaacgg ccttcaaaga
     4501 ggaattccca gctcgttcag ctgtggaggt agctcgtctt cctcgtgatg taaaagtcga
     4561 aattgaagtt atcgcagaga ttggataagc tagttgaagt ttggtgttgc caaacttctt
     4621 ttgatataag gagaaaaaga tgacaaagaa acaacttcac ttggtgattg tgacagggat
     4681 gagtggcgca gggaaaactg tagccattca gtccttcgag gatctaggtt atttcaccat
     4741 tgataatatg ccgccagctc tcttgcctaa gtttttgcag ctggttgaaa ttaaggaaga
     4801 taatcctaag ttggctttgg tagtggatat gcgtagccgt tctttctttt cagagattca
     4861 agctgttttg gatgagttgg aaaatcaaga tggtttggat ttcaaaatcc tctttttgga
     4921 tgcggctgat aaggaattgg tcgctcgtta caaggaaacc agacggagtc acccactagc
     4981 agcagacggt cgtattttag atggaatcaa gttggaacgt gaactcttgg cacctttgaa
     5041 aaatatgagc caaaatgtgg tggatacgac tgaactcact ccacgtgaac tgcgcaaaac
     5101 ccttgcagag cagttttcag accaagaaca agcccagtct ttccgtatcg aagtcatgtc
     5161 tttcggattt aagtatggaa tcccgattga tgcggacttg gtctttgatg tccgtttctt
     5221 gccaaatccc tattatctac cagaactgag aaaccaaacg ggtgtggatg aacctgttta
     5281 tgattatgtc atgaaccatc ctgagtcaga agacttttat caacatttat tggccttgat
     5341 tgagccgatt ctgccaagtt accaaaagga aggtaagtcc gttttgacca ttgctatggg
     5401 atgtacgggt ggacaacacc gtagtgtggc atttgctaaa cgcttggcgc aggacttatc
     5461 caagaattgg tctgttaatg aagggcatcg cgacaaagac cgcagaaagg aaacggtaaa
     5521 ccgttcatga gaaaaccaaa gataacggtg attggtggag ggactggaat tcccgtcatt
     5581 ctaaaaagtc tgcgggaaaa agatgtggaa atcgcagcta tcgtgacggt ggcagatgat
     5641 ggtggttctt caggtgaact ccgaaaaaat atgcaacagt tgacaccgcc aggtgatctt
     5701 cgtaatgtcc ttgtggccat gtcggatatg cctaagtttt atgagaaggt ctttcagtat
     5761 cggttctctg aggatgccgg agcctttgct ggccatccat tgggaaatct catcattgct
     5821 ggcttgtcag aaatgcaggg ttcaacctat aatgccatgc agttattgag caaatttttc
     5881 catacaacag ggaaaattta tccttccagt gaccatcctt tgacccttca tgcagtcttt
     5941 caggatggga cagaagtggc tggagagagt catattgtag accatcgagg cataattgac
     6001 aatgtctatg tgaccaatgc cctaaacgat gatacgcctc tggccagccg tcgagtagtg
     6061 cagaccatcc ttgaaagtga catgattgtc ctagggccag gttccctctt tacctctatt
     6121 ttgcccaata tcgtgattaa ggaaattggg cgggctcttt tggaaactaa ggcagaaatt
     6181 gcctatgtct gcaatatcat gacccaacgt ggggagacgg aacactttac agatagcgac
     6241 cacgtggaag tcttgcatcg tcaccttggt cgccctttta tcgacactgt cttggtgaat
     6301 attgaaaaag tgcctcagga atacatgaat tccaaccgtt ttgatgaata cttggtgcaa
     6361 gtggaacacg attttgtagg tctttgtaag caagtttcgc gcgtgatttc atctaacttc
     6421 cttcgtctgg aaaatggcgg tgccttccac gatggagatt tgattgtgga cgagttgatg
     6481 cgcattatac aggtgaaaaa atgagtttca cagtagcagt aaaagaagaa atcctgggcc
     6541 aacaccatct gagctggcat gaattatctg ccattatcaa aatgtctggt agcatcggtc
     6601 tctcgacttc gggcttgact ttgtcagttg tgacagaaaa tgccaaactg gcccgtcacc
     6661 tctatgagtc ctttctccat ttctatgaaa tcaaatctga aattcgtcac caccaacgga
     6721 gcaatcttcg caagaatcgc gtctataccg tttttacaga tgaaaaggtg caggatttgt
     6781 taagtgattt gcacttggca gactctttct ttggcctgga aacaggtatt gatgaggcga
     6841 ttttatcgga tgaggaagca ggtcgtgcct atctctgtgg cgctttcttg gcaaatggga
     6901 gcattcgtga ccctgagtca ggcaagtacc agttggaaat cagttctgtt tatctggacc
     6961 acgcgcaagg aattgcctcc cttctccaac agtttttact ggatgccaag gtgcttgagc
     7021 gcaagaaggg ggctgtgacc tatctccagc gagcagaaga cattatggac ttcttgatag
     7081 taataggagc catgcaggca cgtgatgatt ttgagcgggt taagattttg cgagaaaccc
     7141 gtaacgacct caatcgggct aataatgccg agacagctaa tatcgctcgg acagtttctg
     7201 ccagcatgaa gaccattaac aatatcagta aaatcaaaga tatcatgggc ttagaaaatt
     7261 tgccagtaga tttgcaggaa gtggcgcaac tgaggattca gcacccagac tactctatcc
     7321 agcagttagc agatagtctc agcacccctc tgaccaaaag tggtgtcaat cacagactca
     7381 gaaaaatcaa taagatagcg gatgaattat aaaaccacga atcctatgtg actcgtggtt
     7441 cttttttata aactagtaga gtgttttggt tgtacttttt gttcagggtc aatgtagttg
     7501 atagcgttgt tgacagcagt tggagcttct ccgaggcctg tcgcaatcag atcaattttt
     7561 ccgtcatagt agcagcagtc accgatagca tagatacctg cttggctgga ttcctgtttg
     7621 ctgttgacga taatcttgtg acggttgagg tcgagccccc agtttttaag gttaccgaca
     7681 gaagatttga aaccatagtt gacaaagagg tggtctaggt caatggtttc agtttcatca
     7741 gatttgactt ttgtgatttc aagtttatca agtgtttttc catttccaag gagttggcta
     7801 ggggcgaatg gtgtcttgat ggttacagat gattcttgca aggcttgaac actgtgttcc
     7861 aaggcacgga aattatctct gcggtgaaca agggtagttg gtgcgatttt ttcaaaagcc
     7921 aaagcccaat ccacagccga gtctccccca ccaagaatcg tcactttctt accagcgtat
     7981 tgctgaatgt tagaaacgtg gtagtggata ttttcatagc cctcaacccc ttcaagttcc
     8041 agcggacgtg gtttgaaggc accgccaccc atagcgatga taactgtttt agtcaggtga
     8101 cttcctttag aagttgtgat ggcaaattct tcttgtttgt caatctcaag aaccgtttca
     8161 ttgagatgaa taggggtatc aaatccattt agctgttcaa tcaagcggtt agtcaactct
     8221 tctccagtca ggtttgggaa gcctggtacg tctaggattt ccttttcagg gtagagaata
     8281 gcaggttgtc cacctagctg gggaagagag tcgatgattt gaaccttggc ttggcgtagg
     8341 tgggcataaa aggctgcaaa aagcccgaca ggaccaccac ccacaatggt aatatcatag
     8401 agttgagaca tagtttctcc tttgtttttt ctagtcagtt tattttatca tatttttgtt
     8461 caatgtaaaa tggactagga tagggaaaaa aatgccagaa aatggtataa taggacgaaa
     8521 gtgttttgat agggaggata tcagggatga attttcaaca attatccaat ctgcaatatt
     8581 ggaccagttt gtttgcaagt ccatggacga tagctatcaa tctgattgat attttgattg
     8641 ttgcttatat tttataccat tttacaaaag ctattgcagg aaccaagatt atgattttgg
     8701 tacgtggagt tttggtgttt attttagctc aaatccttgc aaatatgatt ggtttgacta
     8761 cgatttcttg gttaatcaat caaattatta cttatggggt tattgcggcg gttgttatct
     8821 tctctccaga gattcggact ggtttggaac gtttgggaag agcgacagat tttttttcca
     8881 atgcccctat tagtgctgag gaacagatga ttcgtgcctt tgttaagtct gttgaataca
     8941 tgagtcctcg taaaatcggg gccttggttg ctattcagcg tgtacgtacc ttgcaggagt
     9001 atatttcgac aggaattccc ttggatgcta agatttctgc agaacttctc attaacattt
     9061 ttattcccaa cactccccta catgatggtg cggtgattat caaagaagaa cgtatcgctg
     9121 tgacgtctgc ctatctgccc ttgacaaaaa acacagggat ttccaaggaa tttgggacca
     9181 gacaccgggc ggctatcggt ttatcagaag tctcagatgc cttgactttt gtcgtatcag
     9241 aggaaacggg aggaatttcg ataacctata atggaagatt taagcacaac ctaacacttg
     9301 atgaatttga aacagaatta cgtgaaatct tacttccaaa agaggaagtg ggtcttagtt
     9361 ttaaagaacg attgctagga ggatggaaac atgaaaaaaa atagtttata tatcatatcc
     9421 tcactctttt ttgcttgtgt cttatttgtc tatgctacgg cgacgaattt tcaaaacagt
     9481 accagtgcta ggcaggtaaa aacggaaacc tatactaata cagtaacaaa tgtccctatt
     9541 gacatacgct ataatagtga taagtatttt attagcggtt ttgcttcaga agtatcagtg
     9601 gtcttgactg gtgcaaatcg cctatcgcta gctagtgaaa tgcaagaaag tacacgtaaa
     9661 ttcaaggtta ctgctgacct aacagatgcc ggtgttggaa cgattgaagt tcctttgagc
     9721 attgaagatt tacccaatgg gctgaccgct gtggcgactc cgcaaaaaat tacagtcaag
     9781 attggtaaga aggctcagaa ggataaggta aagattgtac cagagattga ccctagtcaa
     9841 attgatagtc gggtacaaat tgaaaatgtc atggtgtcag ataaagaagt gtcgattacg
     9901 agtgaccaag agacattgga tagaattgat aagattatcg ctgttttgcc aactagcgaa
     9961 cgcataacag gtaattacag tggttcagta cctttgcagg caatcgaccg caatggtgtt
    10021 gtcttaccgg cagttatcac tccgtttgat acaataatga aggtgactac aaaaccagta
    10081 gcaccaagtt caagcacatc aaattcaagt acaagcagtt catcggagac atcttcgtca
    10141 acgaaagcaa ctagttcaaa aacgaattaa aaatagaaaa ggattttata acaatgggta
    10201 aatattttgg gactgatgga gtccgtggag aagctaacct agaactaaca ccagaattag
    10261 cctttaaact aggacgtttt ggaggctatg ttcttagtca acatgaaacg gaagcgccga
    10321 aagtctttgt aggacgtgac acacgtattt caggggaaat gctggaatcg gccttggtgg
    10381 caggtctcct ttcagtaggg attcacgtat acaaacttgg tgtccttgca acaccagcag
    10441 tagcttactt ggttgaaact gaaggagcaa gtgccggtgt catgatttct gctagccaca
    10501 acccagccct tgataacgga atcaagttct ttggcggtga tggcttcaaa ctagatgatg
    10561 aaaaagaagc agaaattgaa gccttgctag atgctgagga agacactctt cctcgtccaa
    10621 gtgcagaagg tttaggaatc ttggtagatt atccagaagg cttgcgtaag tatgaaggat
    10681 accttgtttc aactggaact cctcttgatg gaatgaaggt tgccttggat acagctaatg
    10741 gagcagcttc taccagtgcc cgtcaaatct ttgcagacct tggtgcccaa ttgacggtta
    10801 tcggggaaac accagacggt cttaacatca accttaatgt tggttcaaca catccagaag
    10861 cccttcaaga agtggtcaaa gaaagtgggt cagctattgg tttggccttt gatggagaca
    10921 gtgaccgctt gattgctgtt gatgagaatg gtgacatcgt cgatggtgac aagattatgt
    10981 acatcatcgg aaaatacctt tctgaaaaag gacaattggc tcaaaataca attgtgacaa
    11041 ctgttatgtc taaccttggt ttccacaagg ccttgaatcg cgaaggtatt aacaaggcag
    11101 ttactgcagt tggtgaccgc tacgttgttg aagaaatgag aaaatcaggc tacaaccttg
    11161 gtggtgaaca gtctggtcac gttatcttga tggattacaa taccacaggt gatggtcaat
    11221 tatcagcagt tcaattgact aaaattatga aggaaactgg taagagctta tcagagttgg
    11281 cggcagaagt aacgatttat ccacaaaaat tagttaatat ccgagtggaa aacgtcatga
    11341 aggaaaaggc catggaagtg ccagctatca aggccatcat cgagaagatg gaagaagaaa
    11401 tggcggggaa cggccgtatc cttgttcgtc caagtggaac agagcccctc ttgcgtgtta
    11461 tggcagaagc gcctacaaca gaagaagtgg actactatgt tgatactatc acagatgtag
    11521 ttcgtgctga aattgggatt gactaaatcc tagaaaacta gatgaaaata aaaaattatg
    11581 gtacaatagc ttataatatt gtagccgatg gagaaagaca tgaatcttaa acgtgaacaa
    11641 gaatttgtta gtcagtatca ttttgatgca cgtaattttg aatgggaaaa tgaaaatgga
    11701 gctcctgaaa ccaaggtgga tgtgaatttc caattgctcc aacatgacca agaaaatcaa
    11761 gtgacttcct tgattgtcat cttgagcttt atgattgtat ttgataagtt tgtcattagt
    11821 ggaacaatct cacaagtaaa ccatatcgat ggccgtattg tcaatgaacc aagtgaattg
    11881 aaccaagaag aggtggaaac cttggctcgt ccatgtttga acatgctcaa tcgtttgact
    11941 tacgaagtga ctgaaattgc attagactta ccaggaatta atttggagtt ctaatatgaa
    12001 attagctgtt ttcacagatt cctctgctta tctcagtgaa gagaccttgc aaagagaaga
    12061 cttgtttgtc ttggatattc ctgtcaatat tgatggtgag gaatatgtcg aaggcatcaa
    12121 tctgtctgct gaggaatttt accaaaaaat ggctcaggct tctgaattgc ctaagaccag
    12181 tcaaccaagt attgccaagt tagatgagat cttaacttcg ctcaaagaac aaggctatac
    12241 acatgccttg gggcttttcc tatcttctgg aatttcaggt ttttaccaaa atatccagta
    12301 tatggtcgat gactatgagg gcttaaccat tgcttttcca gacactttga ttacaagtgc
    12361 tcctctgggt atcatggttg aaagcgtctt taactggcgt gatcagggcg atgattttgc
    12421 cagcattcag gataagctag ccattcaaat cagccgtacg tcagccttta tcatggtaga
    12481 tgacttggat catttggtaa aaggtggacg cctttcaaat ggggctgcca ttttgggcaa
    12541 tttgcttagc attaagccaa tcctttattt taacgatcaa ggtgtgattg aagtttacga
    12601 aaaagttcgt actgaaaaga aggccaccaa acgcttaatt gaaattatca aggaaacaac
    12661 ggcttcaggt caataccggg tcattgtcat tcatgggaat gctcctgaaa aggctgaaga
    12721 attgcgtcag catttgcttg attttggctt gggttcggat gtttcacttg ctacatttgg
    12781 tagtgtcatt ggaacgcacc taggagcagg aagtattgct ctgggttata ttccagtgat
    12841 ttagtaggca cttctaggct agttaatctt agcaattgaa cacggactac ctgcctcttg
    12901 aaaaaagatg tctgtcttgc ctttcgtgga aagtcagtgc cattccctat ttttcatggg
    12961 tggctaagat cctttgtatc ttgataattg aacacgcctg gaaccctgtg tgaaaaagat
    13021 agttcttcca aggagtagac acttcttgat cagaattcct attttcactt tgtgttctta
    13081 cagactttgt atcttagaca ggagtagaga tgagtattcg agtaattatt gccggtttta
    13141 agggaaagat gggccaggct gcttgccaga tggtcttgac tgattcagat ttggacttgg
    13201 tagcagtttt ggatcctttt gagtctgagt cagaatggca gggtattcct gttttcaagg
    13261 ataaggctga tttagctggt tttgaagcgg atgtctgggt agactttact actccagctg
    13321 ttgcctacga aaatacacgt tttgctcttg aaaatggctt tgctccagta gttggaacga
    13381 ctggtttcac gagtgaagaa attgcagagc taaaagaatt ttctcgtgcc caagacttgg
    13441 gtggtctgat tgcccctaac tttgccttgg gtgctgtctt actcatgcaa tttgcgacgc
    13501 aggctgccaa atatttccca aatgtggaga ttattgagct ccatcatgac aagaaaaagg
    13561 atgctccgag tggaacagcc attaaaacag ctgagttgat ggcagaggtt cgagagtcca
    13621 ttcagcaagg tgcagcagat gaggaagagc tgattgctgg tgctcgtggt gctgactttg
    13681 atggtatgcg catccactca gttcgtttgc caggtttggt agcccatcag gaagtcatct
    13741 ttggcaatca aggagaagga ttgaccctcc gtcatgactc ctatgatcgc atctccttca
    13801 tgacaggagt caatttggga attaaagaag ttgtcaagcg tcatgagctt gtctatggat
    13861 tagaacactt attatgagat taacgcaaat gccttctgaa tttcagaagg ctttaccagt
    13921 attagaaaaa attaaagaag caggatttga ggcttatttt gttgggggct ctgttcgaga
    13981 tgcccttctc catagcccta tccacgatgt ggatattgcg acgtcttctt atccagaaga
    14041 gaccaagcag atttttccgc gaacagccga tatcggaatc gagcatggaa ccgtcttggt
    14101 cttagatggg gatgaggagt atgaggtaac aacctttcgg acagaggatg tctatgtgga
    14161 ctatcgcaga cccagtgcgg tttcctttgt gcgatcgcta gaagaagacc tcaaacgccg
    14221 tgatttcaca gtcaacgcct ttgccttgga tgagacagga gaaatcgttg acttgttcca
    14281 tggtttagaa gatttggaaa agcaagtctt gcgagcagtt ggagtggcta gtgagcgttt
    14341 caacgaagat gctttacgga ttatgcgtgg tttccgtttt caggctagtc ttggttttgc
    14401 acttgagcca gaaacattta aagctatgaa gaccttgacg ccgcttttgg agaacatttc
    14461 tgtagagcgt accttcgtcg agtttgataa actcttgctg gctccatttt ggagaagggg
    14521 cctggcttcc atgattgaga gtcaagctta tgactatctc cctgatatgg catctagcca
    14581 ggacaagctc aacagactgt ttgatttgga gactgatttt acttttgaat cctctgaaca
    14641 agcctgggcg gctttactat gggctttgga gattgaaaat gcgcagtcat ttttgaaatc
    14701 ttggaagacc tcacgccagt ttgccaagca agttcaggat ttgctgatta ttttggctct
    14761 gcgtgaaaat ggagaattga gcaagcgaga ttgttatcgc tttgacatag atttgctttt
    14821 acaggctgaa aatcttcgtc aagctcaagg aaaagaagtc aacccacaag ccatcacaga
    14881 aaaataccaa agcttgacta tccatgacaa gaaagagatt cagattaatg gcggtatttt
    14941 gatcaaggaa tatggctatc agccaggccc agacttggga gagattttaa cagagattga
    15001 gtttgccatt gtcgatggag aattggagaa taatcgtgaa gccatccatg cttacctgag
    15061 ggagaaaaaa tgagtgattt tatcgttgaa aaactaagta aatccgttgg tgacaagacc
    15121 gtttttaggg atatttcctt tattatccat gacttagaca gaattggttt aatcggtgtc
    15181 aatggaactg gcaagaccac ccttttggac gtcctttctg gtgtttctgg atttgatggg
    15241 gatgtcagtc ctttttcagc taaaaatgat taccagattg gttacttgac tcaggatcct
    15301 gattttgatg atagaaagac agttttggat acggttctat ctagtgaact caaggaaatc
    15361 cagctcattc gtgagtatga attgattatg ctcgactata gtgaggacaa gcaggcgcgt
    15421 ttggaacgtg tcatggcaga gatggactct ctccaagctt gggaaatcga gagtcaggtc
    15481 aagaccgttc ttagcaaatt gggcattcaa gacttatcta ctcctgttgg ggaattgtca
    15541 ggtggtctga gaagacgggt acagttggca caagtcttac ttggcaacca cgacctcttg
    15601 cttttggatg agccgaccaa ccatctggat attgcgatta ttgagtggct gaccctcttt
    15661 ttgaaaaatt ctaagaagac cgtccttttt atcactcacg atcgttattt cttagacgct
    15721 ttgtcaacac ggattttcga gttggatcgt gcaggcttga ccgagtacca gggaaattac
    15781 caggactatg ttcgcctaaa ggcggaacag gatgagcgcg acgcggctct tcttcacaaa
    15841 aaagaacaac tctacaaaca agaattggtc tggatgcgca gacaaccgca ggcgcgtgcg
    15901 accaagcagc aggcccgtat caatcgattc catgatctga aaaaggaagt ttcaggcagt
    15961 agtgctgaga cagacttgac catgaacttt gaaaccagtc ggattgggaa gaaagtcatc
    16021 gagtttcagg atgtttcctt tgcctatgaa aacaagccta ttttgcaaga ttttaatctc
    16081 ttggtgcagg ccaaagaccg tatcggaatc gttggggaca atggtgttgg aaaatcaacc
    16141 ctgctcaact tgattgcagg aagtcttgag ccaactaaag gacaagttgt gattggggaa
    16201 actgttcgca tcgcctattt ctctcagcaa attgagggtt tggatgaaag caagagagtt
    16261 atcaattacc tgcaggaagt ggcagaagag gtcaagacca gtggcggttc tacgacttcg
    16321 attgcagagt tgctggagca gttccttttc ccacgttcga cgcatgggac cttgattgag
    16381 aaattgtcag ggggtgagaa aaaacgtctt tatctcctca aactgctttt ggaaaaacca
    16441 aatgttcttc ttttagacga gccaaccaat gacctagata ttgcaacttt gacagtctta
    16501 gagaatttct tgcaaggttt tgcaggtccc gttttaacag tcagtcacga ccgctatttc
    16561 ttggataagg tagcgaccaa gattctcgct tttgaggatg gcaagattcg tcctttcttt
    16621 ggtcattaca ccgactatct tgatgaaaaa gcttttgaaa cagatatggc caatcaagtg
    16681 caaaaggtcg aaaaggaaaa agtggtcaag gttcgagaag acaagaaacg catgacctac
    16741 caagaaaagc aggagtgggc aagtattgaa ggtgatattg ataccttgga aaaacgtatc
    16801 gctgctattg aagaggaaat gcaggctaac ggctctgact ttggtaagct ggctactctc
    16861 caaaaagaat tggatgagaa aaatgaagca ctccttgaaa aatacgaacg ctatgagtat
    16921 ctcagtgaat ttgatagtta agactattcg aaaatcaaag tgcaaactat gtcggcttca
    16981 cattgccgac tcaagtacag cctgtgaccg gcttcctaat ttgcactttg atttttattg
    17041 agtataaaag aatagaaaaa tcccgtctca tgaaaggatt tctctattct tttttggttt
    17101 cttgatgaaa gatattttgc caggtttcgt ggcgacgcca gatactggta tggatgatac
    17161 catctaactc atagcagatg agtttggttt tttgactgat ggaagtaatt tgaatgtcct
    17221 tgatagcaga atttaactct tttttggtct tataagcctc tttatccatc tgctctccat
    17281 cttggcgaat atagacaaaa tcatcagtca agagttcttc tagttggttt ccttggtcaa
    17341 tcaattgttc acgcataagc aattttttat agacattgtc taaaatttca tcctcaggga
    17401 taggtgctgg ttcgatatgg acatcggtat caaagacgcc aaaacgctcc tccagcatag
    17461 actcgacctg atccgcgatt tcatggcttt caaaaacaga caagtcagga ttcatctcta
    17521 gtgtaatatc caggtagatg ttgctaccgt aggtgcgacc tctttgcgat ttgaccttgc
    17581 tgattttggg aatttccatg atagcctttt ggtagtcctc gagcaggcgg tcgtcaaagc
    17641 catctgaaag actaaaggaa gactcgatga agatatcata ggcagtcttc aagataaaga
    17701 aagtgatgat gatagcaacc agtttatcca caatcggata attgaaacta ctagctagga
    17761 tggcaatggc ggttccaagt gaggtaacag cgtcagaaag attgtcctta gcagctgcct
    17821 tcagcgcctt ggagttggat ttcttactga ggcgagtatt gtagagatag accacaaaca
    17881 taatcgctgc agaaatgatt cctagagttg caccaagagg atcaatgacc gtttcttccc
    17941 gactgagaat cttttgaatg gtatctctta gaacatcgaa accgacatag aacatgatga
    18001 tagaagtgat caagcttgcc aaatcttcaa tcttccaatg accaaaacgg tggtcacggt
    18061 ctgcaggctg gcgcgccatc cgaatcccga ttaagagggc cacatttcca atgatgtccg
    18121 atacgttatt aaaaccatcg gccaccaaac tggatgaatg aaggagatga ccagctgcta
    18181 atttggctgc agacaagatc aaataggtcg aaatactgat aatggctcca cgctcagcta
    18241 acttgagatt tgagatagat tgcttcattc aacttccttt ctagtcacat agcattctac
    18301 cattatactg gttttcaagg aaaaattcaa ataaggcagt ttttactctt tgaaaactcc
    18361 ccaaaatttg gtataatggt actactcaag ggagtagctg gcagaaacct gtgatagtgt
    18421 cgtcattccg aattttatgc tgaaaagtat gctttccggc cctatcttaa acagcgagac
    18481 ttgttatgat taacaggtct ctttttgttt gtcgtgaaaa gatatgacag aaagagagtc
    18541 tgttttgcac acaatgtcaa ggaggagaca catgtcaaaa gaacaaaaac gccaagcgtt
    18601 ttatactcag agccctgaag aggtcttgca ggctgtggat gcgaccgagc aaggtttgtc
    18661 atcaagtgag gcggaaaagc gccttgccga atttgggcac aatgaactcg aagaaggcga
    18721 gaaacgatca atcttggtca aattcatcga gcaatttaag gatttgatga ttatcatcct
    18781 agttgcggca gcaatcttgt cagtcgtgac ttctggtggg gaagatatcg cagatgccat
    18841 tatcatccta gctgtggtta tcatcaacgc tgcctttggt gtttaccaag aaggaaaagc
    18901 tgaagaagct attgaagccc tcaaatccat gtctagtcca gttgcccgcg ttcttcgtga
    18961 tggacacatg gcagagattg actctaaaga attggtacca ggcgatatcg ttgcccttga
    19021 agcaggtgac gtggtaccag cggacctacg tttgctagaa gccaactctc ttaaaattga
    19081 agaagcagcc ttgacgggtg aatctgtacc agtcgaaaaa gacttgtcag tcgagcttgc
    19141 gacagatgct ggtattggtg accgtgtcaa catggccttc caaaactcaa acgtaaccta
    19201 tggtcgtggg atgggtgttg ttgtcaatac aggtatgtac actgaagttg gtcatattgc
    19261 tggtatgctt caagatgcgg atgagactga tacaccactc aaacaaaact tgaacaacct
    19321 ttctaaggtc ttgacctatg ctatcttggt cattgccctt gttacttttg tagtgggtgt
    19381 cttcattcaa gggaaaaatc cacttggtga gttgttgact tctgttgccc ttgctgttgc
    19441 agccattcca gaaggacttc ctgctatcgt taccatcgtt ctttctcttg gtactcaagt
    19501 tttggccaaa cgacattcca tcgttcgtaa gttgccagca gttgaaacac ttggttcaac
    19561 tgaaatcatc gcttctgata agactggtac gctgactatg aacaagatga cagtcgaaaa
    19621 agtcttctac gatgcggttc tacatgactc agctgatgat attgaactag gtcttgaaat
    19681 gccactactt cgttcagttg tcttggccaa tgatacgaaa atcgatgtgg aaggtaactt
    19741 gattggtgac ccaaccgaaa cagcctttat ccaatatgcc ttggacaagg gctatgatgt
    19801 caaaggtttc ttagagaaat atcctcgtgt agctgaattg ccatttgact ctgaccgtaa
    19861 gctcatgtca acagttcacc cattgccaga tggtcgtttc cttgtagcag tcaagggtgc
    19921 gccagaccaa ctcttaaaac gttgtcttct tcgtgataag gctggggata ttgctccgat
    19981 tgatgagaag gttacaaatc tcattcatac aaacaattct gaaatggctc atcaagcctt
    20041 gcgtgtcctt gcaggtgctt ataagattat cgatagtatt ccagaaaatc tcacttctga
    20101 agagcttgaa aatgatttaa tttttactgg tttgattggg atgattgatc ctgaacgtcc
    20161 tgaagctgct gaggctgttc gtgtggctaa ggaagctgga attcgtccaa ttatgattac
    20221 aggtgaccac caagacaccg cagaagctat tgccaaacgt ttgggaatca ttgacgcaaa
    20281 cgatacagaa gaccacgttt taactggtgc tgagctcaac gaattatctg atgaagactt
    20341 tgaaaaagtt gttggtcaat actctgttta tgcccgtgtg tctccagagc acaaggttcg
    20401 tatcgtcaag gcttggcaaa aacaaggtaa ggtcgttgcc atgacaggtg acggtgtcaa
    20461 tgatgcccca gctctgaaaa cagcagacat cggtatcggt atgggaatca ctggtacaga
    20521 ggtttctaag ggggcttctg atatgattct tgcagatgat aactttgcga ctattatcgt
    20581 cgcagtggaa gaaggacgta aggtcttctc aaatattcaa aagactattc agtacctact
    20641 ttctgccaat actgctgaag tattaaccat cttcctatca accttgtttg gttgggacgt
    20701 cttgcagcca gttcatcttt tgtggattaa cttggtaacg gataccttcc cagcaattgc
    20761 actaggtgtt gaacctgcgg aacctggtgt catgaatcat aaaccacgtg gacgcaaggc
    20821 aagcttcttc tcaggtggtg ttttgagttc tatcatttat caaggtgtac tccaagcagc
    20881 tcttgttatg agtgtttatg gccttgcgat tgcttaccca gttcatgtgg gtgacaatca
    20941 tgctattcat gcagatgccc taacgatggc ctttgcaacc cttggtttga ttcagctctt
    21001 ccatgcctac aatgtcaagt ctgtctacca atccatcttg acagttggcc cattcaagtc
    21061 taagaccttt aactggtcca tcttggtatc ctttatcctt ctcatggcaa caatcgttgt
    21121 agaaccgctt gaaggaatct tccacgtaac caaactagac ttgtcacaat ggggaattgt
    21181 tatggctgga agcttctcaa tgattatcat cgtcgaaatc gttaagttta ttcaacgcaa
    21241 actcggtttt gacaagaatg cgatttaagg gaggtttcgg atgtcagcat atcaattacc
    21301 gaccgtatgg caggatgaag ctagtaatca aggagctttt acggggctaa acagaccaac
    21361 agtaggtgcc cgtttcgaac aaaacttgcc aaaaggagaa caagcttttc agctttattc
    21421 actgggaaca ccaaatggtg tgaaggttac tatcttattg gaagaattac tagaagctgg
    21481 ttttaaggaa gcggcttacg acttgtataa gattgctatc atggatgggg atcaattcgg
    21541 atcagacttt gtgaagctca atccaaattc caagattcca gccttattgg accagtcagg
    21601 tactgaagat gtaagagtct ttgagtctgc tcatattctt ctttaccttg ctgagaaatt
    21661 tggagccttt ttaccaagta atcctgtgga aaaggtagaa gttttgaatt ggctattctg
    21721 gcaagcaggt gcagcacctt ttctaggtgg gggatttgga catttcttca attatgctcc
    21781 tgaaaaattg gaatatccta ttaaccgttt tacaatggaa gtgaaacgcc agttggattt
    21841 attggataag gaattggctc agaaacctta tattgcaggc aatgactata cgattgcaga
    21901 tattgctatc tggtcttggt atggacagtt agttcaagga aatctttacc aaggttctgc
    21961 aaaattcttg gatgcctcaa gttatcaaaa tctagtaaaa tgggcagaaa aaattgccaa
    22021 tcgtccagct gttaagcgtg gcttggaagt aacttataca gaaattaaat agcaaaaaag
    22081 tcatcttcgg atggcttttt gctacagttg agggaaaggg tttgcagtta tcggcttttg
    22141 tgctataatt gctataatat agtaaaaagc aagaggagtg tgaggaagtg gaaaagaaaa
    22201 ttgtgaagga tatcttattt ttatctcaag tgtctcagcc ggcaagtcag gaggaccttt
    22261 atcttgccag agatttgcag gatacactct tagcaaatca tgatacctgt gttggtctag
    22321 ctgccaatat gattggggtg cagaagcgcg tgattatctt taatcttggc ttggttcccg
    22381 tggtcatgtt taacccagtg cttctgtcct ttgaaggatc ctatgaggca gaagaaggct
    22441 gtttgtcctt ggtaggcgtg agatcaacta agcgttatga aaccataagg gttgcctatc
    22501 gtgacagcaa gtggcaggaa cagaccatta ccttgacagg cttcccagct cagatttgcc
    22561 agcatgagct ggatcacttg gaaggacgaa tcatttagga ggaaagcaaa tgaaacgaat
    22621 agtctttgaa cttattttta tcgcaacgac ctggtatatc tttttaccgc cccttaacct
    22681 gaccagctgg gaatttctct tcttcctctg tgggcatttg ttagttgtgg caatcttatt
    22741 tggctttggc aaggggataa accttgtcaa aacggttcat gtgcgccacg gtaaggcgga
    22801 agctgcctta aatcttgagg gtttcaaaat caatcggtta gggaaaattc tgttagcttc
    22861 gattggagga attcttctct tggcagcttt ggtttccttg gtaacttcca gcatgtttca
    22921 ggctaaaaat tatgccaatg tagtcacggt tacggaaaaa gactttactg aatttcctag
    22981 gagtgacacc agtaaggttc ctatcctaga tagaagtact gctgaaaaaa ttggagaccg
    23041 ctacttgggt tccctaaccg ataaggtgtc gcaatacgta gcggcagata cctataccca
    23101 attgacaatt gatgggaaac cttatcgggt cacaccacta gaatatgcag accctatcaa
    23161 atggtttaac aatcaagcca agggaatcgg tgagtatatc aaggtggaca tggtaactgg
    23221 aaatgcggat ttggtggact tgaagacacc aatcaagtat tcagactcgg agtattttaa
    23281 ccgtgatgtc aaacgtcacc tgcgcttgaa gtacccgacc aaaatcttta aaactccatc
    23341 ttttgaggtg gacgatgagg gcaatccttt ctatgtagca acggtttacc aaaagcaatt
    23401 tggacttgct gttcctcgtc ctgcttcagt cattatcttg gatgctacaa atggagaaac
    23461 caaggaatac agcttatcag atgttccaga atgggtggac aggatctatc cagcagagga
    23521 aaccattgag caaatcaact acaacggcaa gtacaaggac ggtttcttga atgccatgat
    23581 ttccaagaaa aacgtgaccc agactaccaa gggctataat tacttgtcta tcggtaatga
    23641 catctatctc tacacaggtg tgacgtcggc taatgcggat gagagtaatc ttggtttcat
    23701 ccttgaaaat atgcgaacag gagaaatcac taagtatagc ttggcttctg cgacagaaga
    23761 atcagcccgt gaatcagcag aaggtgctgt tcaggagaaa tcctacaaag caaccttccc
    23821 aatcctcatc aacctcaatg acaagcctct ctatatcatg ggcttgaagg acaatgctgg
    23881 cttggtcaaa gagtacgccc tggtagacgc agtcgagtac caaaatgtta tcgttgctac
    23941 tacagtggaa gagatgctca gcaagtatgc caataaaaac gaccttgaaa ttgacaatgc
    24001 aacgacagaa agcatcaatg gagtagtagc agacctcaaa tcagctgtta tcaagggaga
    24061 cactgtctac ttctttaaag ttgatggcaa gatatacaag gtcaaggctt cagtatccga
    24121 tgaccttcct taccttgaaa atggtaaaac cttcgaaggt caagtaggaa aagacaatta
    24181 tctcaagacc tttaagctac ggtaaaaata ggtttttttc agaaagtata tgttataata
    24241 aggtaaatta agcctaatgg aggacaaaga aatgggtttt tatttgatgg ttgcttcaat
    24301 gctactcgga ctgctcgctt tgaagatagg tttttctcag ttcaaggaga aaaaagataa
    24361 attcttatct atcttaacaa gtttagctgg cacagccctt gttctcgtgg ctgtctggtt
    24421 aggatggccc aaataaatag aaaaacctcg gtcaaaccga ggtttttcaa atgaatttct
    24481 tggttgtggc taaaaaatat gctacactat caatatgaaa attttaatcc caacagcaaa
    24541 agaaatgaac acagacttgc caagtatcga ggcaatttct ttaaaaccag aaagtcaggc
    24601 cgtgcttgat gccttggctc tctattctgc cagtcaattg gagagtttct acaaggtatc
    24661 agctgagaaa gcggcggaag aatttcaaaa tatccaagct ttgaaaaggc aaactactca
    24721 acactatcca gccttgaaac tttttgatgg gcttatgtac cgcaacatta agagagataa
    24781 gctgaccgag gcggaacaag attatcttga aaatcatgtc ttcattacct cggctttgta
    24841 cggtgttgtt ccagccttgt cacccatggc tcctcaccgt ttggattttt tgatgaaatt
    24901 aaaagtcgct ggtaagactt tgaagagcca ttggaaggca gtctatgatg aagctctgaa
    24961 gaaggaagaa gtgattttct ctctcttgtc atcagagttt gagactgtat tttctaagga
    25021 aatcagagca aagatggtga ccttcaaatt catggaggat agagggggtc agctgaagat
    25081 tcactcaact atctccaaga aggcgcgcgg ggcctttcta acagctttaa tagaaaatca
    25141 agtacaaact gtgggggaag cacgtcgctt gaactttgct ggatttgttt accgagaaga
    25201 tttgtcacaa ccacagggat tggtttttgt aaaggaagta tagaaatcag atattttgta
    25261 tttggcaata tgtatcatca gctgttttag tttataaatg agaaaaaaag cgaacaagct
    25321 agtcttctga gtgtcagaaa agtagtcttg ttcgctttta ttatgttata ctcttcgaaa
    25381 atctcttcaa gccacgtcag cgtcgcctta ccgtatatat gtcactgact tcgtcagttc
    25441 tatctacaac ctcaaagcag tgctttgagc agcttgcggc tagcttccta gtttgctttt
    25501 tgatttttat tgagtgttag ttacttgata gcttcgacca agtcttgagc ttgtttttca
    25561 agtgagttta ggactgtttc ttcaagaacc aattttccgt ctgcccaggc agagtcatta
    25621 acacgtgcag cagtgaaatc accaacgcct tgtgtacgga taaatggcaa gaggtctttg
    25681 tagatagcga aaagttgatc gtgccctgca ttggctacag atgatactgt gacaaacttg
    25741 tcttgaaggg cagaaacgcc acgtgtatca gacaagtcaa gggcacgaga tagccagtca
    25801 agcaagtttt tcactgtacc agggatagag aagttgtaga ctggagagaa aatccagata
    25861 gcatccgcaa cgagaactgc ttcacgagca gcagctacag ctggatgtgt tggaacttcc
    25921 aaatcttggc tgaagagagg aagggctgaa taatcaaggt agctaacttc cgctttacca
    25981 gcaagtgctt tctcagcttc gagcgccatt tggtggttga aagaaccttg acgtagtgat
    26041 ccgacgataa ataatacttt tttagacatg atgtgtctcc tttttcttaa aatttcgaga
    26101 actctctcgt tgttataaaa tatattacaa caaaacaaaa gaacttgcaa gaaatttgct
    26161 cagagtttat ttgaaaattg taaaatttgg gaaactctag tcatttgtga ctgaaaaagt
    26221 aagaactgtt tcactttcaa aatcggtttt gtttgaaggg agaaatagaa ttggttgctc
    26281 aaagcacagc tttgaggttg cagataaagc tgacgtggtt tgaagagctt ttcgaagagt
    26341 attcttatat tcacttgtaa taaagcttaa tagatggtaa aatagacgag tgaaaaaaag
    26401 acaaaacaaa gcaaaaaata atctactgtg gcagtatggt ctagggatga cgattttgtt
    26461 tgtggttatc agtgcttcct ttctgtatat ggtttctctt agcatgaaac cctatcaaac
    26521 agctaaaagt gaaggagaaa aattagctca gcagtatgca ggattagagc aggctgatca
    26581 ggttgattta tacaatggct tggaatctta ttacagcgtt cttggtcgta ataaacagca
    26641 agaagcgctt gctgtcctga ttggtaaaga tgaccataag atttacgttt atcagctaaa
    26701 tcagggtatt tcacaagaaa aagcagaaac ggtttctaag gaaaagggag ctggcgagat
    26761 tgacaagata acctttggcc gttatcaaga caagccaatc tgggaagtca agtcaggatc
    26821 taatttttat ctagtagatt ttgaaacagg agcattggtc aacaaggagg gcctatgaaa
    26881 ttatccaacc gtgttttaga aatggaagaa agtgtgactt tggctgctgg agcccgtgcc
    26941 aaagcactga aggctgaggg tagagatatt ttgtctctaa ccttgggtga gccagatttc
    27001 actactccca aaaatatcca agatgccgcc attgcatcga ttcgagatgg gcgtgcttct
    27061 ttttatacag taacctcagg tctgccagag cttaaggcgg cggtcaatag ctactttgag
    27121 cgcttttacg gctattctgt agcgtcaaat caagtgacag tcgctgcggg agccaaatat
    27181 tctctctata ccttctttat ggctgtggtc aatccaggtg atgaagtcat catcccaacc
    27241 ccatactggg ttagctatgg agatcaggtc aagatggtag aaggcgttcc cgtctttgtt
    27301 tctgctaagg aagacaatca ctttaaggtg accgtagagc agttagaagc agctcgcact
    27361 gacaagacca aggttttggt gctgaattcg ccatctaatc ccacaggtat gatttacacc
    27421 tgtgaggaac tcttggcaat tggaaactgg gctgtagaaa atgatattct catcctagca
    27481 gacgatatct atggccgctt ggtttataat ggtcatgagt tcacaccgat ttctagccta
    27541 tcggaagcga ttcgcaagca aacagtggtc atcaatggtg tgtctaaaac ctatgccatg
    27601 actggttggc ggattggtta tgccgttgga gaagcagaca ttatcgctgc catgtccaag
    27661 attgcaggtc aaacaacttc gaatccgtca gcagtagccc aatatgcagc agttgaggct
    27721 ctatcaggtg agcaagatac tgtagaaagc atgcgtcagg cctttgagga acgtcttaat
    27781 actatctatc ccctccttgc agaggtgcca ggatttgaag tggtcaaacc gcaaggggcc
    27841 ttctatctct tcccaaatgt caaaaaggcc atggagatga aaggctacac ggatgtgaca
    27901 gactttacaa ctgctatctt agaagaagcc gaagtggcct tggtaacagg agctggattt
    27961 ggagcaccag aaaatgtccg cctcagctat gcgacagacc tagacacgct taaagaagca
    28021 gtcgaacgct tgaaagcatt tatgggtagt gagaatgatt gatcattttg agattaaggt
    28081 aaaggattta caaatttcag aaggatttta taggagtttt ctcgctcctt tggactataa
    28141 attggctttt aagactagtt ctctaattag ttttctatcc ccgaacagcc ctcatcctgg
    28201 tggtgatttt tggctgactc agggaacaca agatcctgtt cattttgctt ttttagcaga
    28261 aaataaggaa gaagttcagg cttgttatga ggctggctta gaggcaggtg ggcgagacaa
    28321 tggggctcct ggttatcgaa gtgagcgtct gatttactat gctgctttta tgattgacct
    28381 ggatgggaac aatatagagg tggtttgcca taaagaataa aaaagaaaag gaaaaataat
    28441 gacaaaacgt gtaacgatta ttgacgtaaa agactatgtt ggtcaggaag tgacgattgg
    28501 cgcttgggtt gccaacaaat caggaaaagg aaaaatcgct ttcttacaat tgcgtgatgg
    28561 aacagccttc tttcaaggtg tggcttttaa accaaacttt gtcgaaaaat ttggtgaaga
    28621 agtgggactt gagaagtttg atgttatcaa acgcttgagc caagaaacgt ctgtttatgt
    28681 gacaggtatt gtcaaagagg acgaacgttc taaatttggc tatgagttgg acatcacaga
    28741 catcgaagtg atcggtgaat ctcaagacta cccaatcaca ccaaaagaac acggaacaga
    28801 ctttttgatg gataaccgtc acttgtggct acgctctcgt aagcaagtag ctgtgttgca
    28861 aatccgtaac gctattatct atgcaactta tgagttcttt gacaagaacg gttttatgaa
    28921 gtttgacagc ccaattcttt caggaaatgc ggcagaagat tctacagaac tctttgaaac
    28981 tgactacttc ggaacgccag cctacttgag ccaatcaggt cagctttacc tagaagcagg
    29041 ggctatggct cttggtcgtg tctttgactt tggtccagtt ttccgtgctg aaaaatcaaa
    29101 aacacgccgt cacttgactg agttctggat gatggatgct gagtactcat acttgacaca
    29161 tgatgagtcg cttgacttgc aagaagctta tgtgaaagct cttctacaag gtgttcttga
    29221 ccgcgcgcct caagccttgg aaaccttgga acgtgataca gaactcttga aacgctacat
    29281 tgcagagcca ttcaaacgta tcacttatga tcaagccatt gacctcttgc aagagcatga
    29341 aaatgatgaa gatgctgact acgagcatct tgagcatggt gatgactttg ggtcaccgca
    29401 cgaaacttgg atttcaaacc actttggtgt gccaacattt gtcatgaact atccagcagc
    29461 catcaaggcc ttctacatga aaccagttcc tggaaatcca gagcgcgtgc tttgtgcaga
    29521 cttgcttgct ccagaaggct atggagaaat tatcggtggg tctatgcgtg aggaagatta
    29581 cgatgccctt gtcgctaaga tggatgaact tggcatggat cgtacagaat atgaattcta
    29641 ccttgacctt cgtaaatacg gtacagttcc acacggagga tttggtatcg gtatcgaacg
    29701 tatggtaacc tttgcagcag gaacaaaaca tatccgtgaa gctattccat tcccacgtat
    29761 gttgcaccgt atcaaaccat aagaacagga aaacgcccat gtggcgtttt ttcgaattct
    29821 agtgttttta cttgcgtaaa aaaatttttt ctagtataat agtttattgt gagcgaacct
    29881 cacttacccc ttgcaaagtc ttggggtcat tagaccaaaa ggaggaacat atcaatggct
    29941 aaatacgaaa ttctttatat cattcgtcca aacattgaag aagaagctaa aaacgctttg
    30001 gtagcacgtt ttgactctat tttgactgac aacggtgcaa ctgttgttga atcaaaaact
    30061 tgggaaaaac gtcgtcttgc atacgaaatc caagatttcc gtgaaggact ttaccacatc
    30121 gttaacgttg aagcaaatga cgatgcagct cttaaagagt ttgaccgtct ttcaaaaatc
    30181 aacgctgaca ttcttcgtca catgatcgtc aaaattgacg cgtaagaagg taaactatga
    30241 ttaacaatgt tgtacttgta gggcgtatga cacgtgacgc tgagttgcgt tataccccat
    30301 caaatgtagc agttgcgact tttactcttg cagtaaaccg tacatttaag agtcaaaatg
    30361 gtgaacgtga ggctgatttt atcaatgtcg ttatgtggcg ccaacaggct gaaaatcttg
    30421 ctaactgggc taaaaaaggc tcacttatcg gggtgacagg tcgtatccag actcgtagtt
    30481 acgataacca gcaaggacaa cgtgtctacg tgacagaggt cgtggctgag aatttccaaa
    30541 tgttggaaag ccgtagtgtg cgtgagagtc acacaggtgg agcttactct gcaccaactg
    30601 caaactattc agcacctaca aattcagtac cagacttttc acgtaatgaa aatccatttg
    30661 gagcaacaaa cccattggat atttcagatg atgatttacc attctaatgg acaactaaac
    30721 ttataaagga gaaaaaacat ggctcaacaa cgtcgtggcg gattcaaacg ccgtaaaaaa
    30781 gttgattaca tcgcagcaaa caaaattgaa tatgttgatt acaaagatac tgagcttctt
    30841 agccgtttcg tttcagaacg tgggaaaatc cttcctcgtc gtgtaacagg aacttcagct
    30901 aaaaaccaac gtaaagtaac aacagctatc aaacgcgctc gcgtaatggc tttgatgcct
    30961 ttcgtaaacg aagattaaag aaaagacccg gttgggtctc tttttcatga gcttgaaaac
    31021 aagaaagcga attaagaccc caacgggtct tttttcacaa gctttgaaat gagagagcga
    31081 gttaggctca gtggctccct ttttacgagt ttgaaaacaa gagaacatat taaaagcacg
    31141 atggagcttt ttcataaata tgtctctttt ctcatccaag aaattaaaat aaaaatgata
    31201 aactttttga aaatagggga tttgcctact ttatgatata atggaaagag ttagattgaa
    31261 agaggtagtg agatggacgc gaaattaaga tacaaggcaa agaagatcaa gattgtcttt
    31321 tttgatattg atgatacatt gcggaattca aagacagggt ttattccaac tacaattccc
    31381 actgttttta aacagttgcg tgaaaaagga attttaatag gaatcgcctc tggacgtggc
    31441 atttttggtg ttgttccaga gattcgtgat ctcaagcctg acttttttgt aactttgaat
    31501 ggagcttata tcgaagataa aaaaggtcag gtcatttatc agcatcagat tgaaaagtca
    31561 gatgttgagg agtatatctc ttgggctaag caagaaggaa ttgagtatgg cttggttggg
    31621 agtcatgatg ccaagttgtc gactcgcacc gatatgatga gtgaagctat caatccaatt
    31681 tatcccgact tagatgtaga tcccgatttc catgaaaaag aagatatcta tcagatgtgg
    31741 acttttgaag ataagggaga tgacttgcac ttgcctgaca gtctctcaga caaacttcgc
    31801 atggttcgtt ggcatcaaca ttcgtctgat attgtgccga tttcaggctc caaagcgacg
    31861 ggggtggaaa aggttgtgga acaccttggc ttgaaaccag agaaggtcat ggtttttgga
    31921 gatggtctca acgacttgga actctttgat tatgctggaa tcagcgttgc catgggaatt
    31981 tctcatgata aaatcaaaga aaaagcagat tatattacaa aaacattaga agaagatggc
    32041 atttttgatg ccttagaagt atttggtatg gtagaaaaag aattgcattt tccacaagta
    32101 gacattgaaa cagtagaagg tcctcttgcg actattaaga ccaatcacgg agacttacgt
    32161 atcaagcttt tccctgaaca tgctcctaaa acagtggcta actttgtatc tctttcaaaa
    32221 gatggctact atgatggtgt cattttccac cgtattatca aggactttat gatccaaggt
    32281 ggagacccaa ctggaactgg tatgggtggc gagtcaatct acggcgaatc ttttgaggat
    32341 gaattctcag aagagcttta caatatccgt ggtgctcttt ccatggcaaa tgctggtcca
    32401 aataccaacg gcagccagtt ctttatcgtg caaaaccaac acctacctta ttctaagaaa
    32461 gaaattactc gtggtggttg gccagaaccg attgcagaaa tctatgccaa tcaaggtggg
    32521 acacctcacc tagaccgccg tcacacggtt tttggtcagt tagctgatga agcatcttac
    32581 gctgtcttgg atgccattgc tgctgttgag acaggagcta tggacaagcc agttgaagat
    32641 gttgtaattg aaactattga aatcgaggac taagatgaaa atcggtgata agctaaaggg
    32701 gcgtattaca gggattcagc cctacggtgc ctttgttgag ttagagacgg gtgatacggg
    32761 gctgattcac atttcagaaa ttcggacagg atttattgaa aatattcatg aaaccttgaa
    32821 agtcgatgaa gaggttcaag ttcaggtagt ggatttagat gaatttacgg ggaaagccag
    32881 tctttctatc cgcactttgg aggaagaaaa gtaccagttt cctagacgga gacgcttttc
    32941 aagcgaccgc tttaactacg gttttgctcc ctttcgacga atgttaccaa tctggactgg
    33001 agaagccctg caccatttaa aaaagaagaa gtagtttaga gttttatatt ttttgtaatg
    33061 ttaatataaa tttgctataa taggaccatg gaagaagaac aattattaaa atcaggagag
    33121 cgcattaacc agctcttttc gacagatatc aaaatcattc aaaatagaga ggtttttagc
    33181 tattcggtgg atagtgttct cttatcacga tttccacgtt ttcctaagaa ggggctgatt
    33241 gtggatttct gtgctgggaa tggagcagtg gggctttttg ctagcactcg tactcaagca
    33301 cagatattgt ctgttgagat tcaggagcgt ttggcggata tggctgaacg ctctgtccgt
    33361 ttgaatggat tagaggagca aatgcaggtc atctgcgatg atttgaaaaa tatgcctgct
    33421 cacattcagg ggagtaaggt ggatatgatt ttgtgtaatc caccctattt caaggtggat
    33481 ccttattcta atctgaacga gagtgaacat tacctcttgg ctcgacacga aatcacgact
    33541 aatttggaag aaatctgtcg tagtgcccag agtattctca agtctaatgg gcgtttggcc
    33601 atggttcatc gtcctgatcg acttctggat attttggata cgttaaaacg acataatcta
    33661 gcccctaagc gcctgcagtt tgtttatcca aaaagagaaa aggaagccaa tatgcttttg
    33721 attgaggcga tcaaggatgg ctcaacaagt ggctttaagg tcttacctcc tttgattgtc
    33781 cacaatgatg atggctctta tacgcccgaa atcgaagaga tttattatgg atcataaggc
    33841 ttatatgtac gttctggagt gtcgtgatgg atcctactat ataggctata cgactgatgt
    33901 gagaagacgc ctcgctatcc acaatagtgg gaagggagcc aaatatacac gagcacgctt
    33961 gccagtcaaa cttatctatg ctcaaggttt tgccagtaag gaagaagcca tgtcggctga
    34021 agctcttctc aagcgtaaga agaggccaca gaaggaagaa tttttatctg aaaatcaaga
    34081 tagaaattta ctcagttatt ttgaagaatc gtggggagtc ctttgactcc tcttaccttt
    34141 gtcaaaaagc gaaaaaaatg ctacaataaa gaaaataaac aaaatgaggt attatcatgt
    34201 ccaagattct agtatttggt caccaaaatc cagactcaga tgccatcgga tcatctgtag
    34261 cttttgccta ccttgcaaaa gaagcttacg gtttggatac ggaagctgtt gcccttggaa
    34321 ctccaaatga agaaacagcc tttgtcttga actattttgg tgtagaagca ccacgtgtta
    34381 tcacttctgc caaagcagag ggagcagagc aagttatctt gactgaccac aatgaattcc
    34441 aacaatctgt atcagatatc gctgaagtag aagtttacgg tgttgtagac caccaccgtg
    34501 tggctaactt tgaaactgca agcccacttt acatgcgttt ggagccagtt ggatcagcgt
    34561 cttcaatcgt ttaccgtatg ttcaaagaac atggtgtagc tgtgcctaaa gagattgcag
    34621 gtttgatgct ttcaggtttg atttcagata cccttctttt gaaatcacca acaacacacc
    34681 caacagataa aatcattgct cctgaattgg ctgaattggc tggtgtgaac ttggaagaat
    34741 atggtttggc aatgttgaaa gctggtacca acttggctag caaatctgct gaagaattga
    34801 ttgacatcga tgctaagact tttgaactca acggaaataa tgtccgtgtt gcccaagtga
    34861 acacagttga catcgctgaa gttttggaac gccaagcaga aattgaagct gcaatgcaag
    34921 ctgccaacga atcaaacggc tactctgact ttgtcttgat gattacagat atcgtcaact
    34981 caaactcaga aatcttggct cttggtgcca atatggacaa ggtcgaagcg gctttcaact
    35041 tcaaacttga aaacaatcat gccttccttg ctggtgccgt ttcacgtaag aaacaagtgg
    35101 tacctcaatt aactgaaagc tttaatgcgt aagattttgg gtgtcagctc aaaatcggaa
    35161 agtctagttt gccttatatc gaaaggagtt tcggctcctt tttttctagg agtgaagtat
    35221 gttagaaaat ggcgatttga tttttgtgag agatgggtca gacatgggac aggccatcca
    35281 gacttccaca ggtaactata gccatgttgc catttatttg gatgggatga tttatcatgc
    35341 tagtggacag gctggtgttg tctgtcaaga accggcagac ttctttgagt ccaatcattt
    35401 gtacgacctc tatgtttatc cagaaatgga tatccagtcg gtgaaggaaa gagcttgcaa
    35461 acatcttgga gcaccctaca atgcttcttt ctatccagat gcacctggtt tctactgctc
    35521 ccagtatata gcagaaatcc tacctatttt tgaaactatt cctatgaaat ttggagatgg
    35581 ggagcaggag attagtgatt tttggaggga gtattacata gaactaggtc tgcctgttcc
    35641 tctgaaccaa gctggtacca atcctagtca gttggcagca tcgcctctgt tacaatgtaa
    35701 agaaaggaat cttcatgatt cagattttta atccatctcg tttgacgaga cagccatttt
    35761 tggagaattg atccgctatc tggaccagta tgaggatgtg attctacggg aaattaaggc
    35821 tcaatttcca gatgttgcag ttgataaact catggaagag tatataaagg caggcttgat
    35881 tctacgtgaa aataagcgct attacctcaa ttttcctacg cttgaatcac ttgatagtct
    35941 tgaactggat caagagattt ttgtcagaga agctagtccg gtctatcaag ccttgttgga
    36001 gcagagtttt gagacggaat tgcgcaatca aatcaatgca gctattttag ttgaaaagac
    36061 ggactttgcg cgcattaaaa tgactctgtc caattatttt tacaaggtca aacagcagta
    36121 tcctttgaca gaaaaacagc aggagctcta tgacatttta ggagatgtta atcctgagta
    36181 tgcactcaag tatatgacgg cttttttgtt gaaatttctc aaaaaagacc agcttatgca
    36241 gaaatgccgt gatatctttg tggacagttt ggttgtctta ggctatattg tgcaaaatga
    36301 agatggaaag tatgagttgg ctatcgattt tgataaggag agattaactt tctacttagc
    36361 gtgatttctt gtttctgagt acattgtttg actttcctta gtattcggta taaactatat
    36421 gtaaccggta acacatatcg gaataaacta aaggagacaa tcatatgtca cttgaaaaca
    36481 aattggaaca agcaacaggc gctgtcaaag aaggttttgg taaagttact ggagacagca
    36541 agacagaact tgaaggagct gttgaaaaaa cagttgctaa ggcaaaagac gttgtagaag
    36601 acgcaaaagg tgctgtagaa ggtgccgttg aaggtttgaa aaacgttttt actaaagaat
    36661 aggaaaaaat caagggtttc attttccctt gattttttct attcttataa ataattttct
    36721 gcgacggctg tatctcctgg gtaggattct ttcttgccct ggatgatttg gtaacaatcg
    36781 gctcccttac ccgcaataat aactgcatct aattcgtgat ttgtgatagc cattgccgcc
    36841 ttgatggctt cttggcgatc cgcaatcttc tcaacaggat gattgatgta gctactaatt
    36901 tcatctgcaa tggccattgg gtcttcatag ttagggtcat cagcagtcag aaagacttga
    36961 atctcagggt gttgattgag gaggaggcca aagtccttac gacgactttc tcccttgttt
    37021 cctgttgatc ccagaaccag agcaatcttt ccggtttgat gagtttcaac cacattgatg
    37081 agttttttca gactatcccc attgtgggca tagtcgatga agaccttggc tccatttttc
    37141 tgagtgagga cttccatacg accaggaacg cgggttgcag cgatgccttt tttgatgtcc
    37201 tcaagacttg ctccgagacg gagacaagca agtccagcag caactgcatt ttcttggttg
    37261 aagttgccaa tgagttggat atcataatct ccagcgagtt tacccgtagc tgaaaagcta
    37321 aaggctttgg aattctcgat ttggttatca aattggctac catagaaatc atggtcttga
    37381 tcttcaacct gttctttcaa gactgagaag tggtccatgt cactgttaat gatgactgct
    37441 cggctatttt ccatcaagag acgcttgtgg tagaaatagt cttcaaagct agggtgttca
    37501 atcgggccga tatggtctgg gctgatattg aggaaaactc ccacatcaaa ggttagacca
    37561 tagacacgtc tgaccagata ggattgactg gagacttcca tgatgaggtg ggtacggtca
    37621 ttttgcacag cctgattcat catgtcaaag aggtcaatac tctcaggggt tgtcaacgct
    37681 gacttaaaga aagtctcgcc atcaagagtt gtgttcatgg tcgacaacat agcaggtcga
    37741 tgcccttgag ataagatgtt ataggcgaaa taggctgctg ttgtcttacc cttagtacca
    37801 gtaaaggcaa ggagtttgag tttttcctgt ggattaccat agaactccat ggcaatcaaa
    37861 ctcatggctt tctttatatc gttcacaatg atgacaggga taccgacttc gtagtccttt
    37921 tcagctacat accaaactaa gccttgtgtt atagcagaaa gaaggtattc ttttttaaag
    37981 gcagcgcctt ttgcaaaaaa aagagtgtct tctgttactt ttcggctatc gtagctgatg
    38041 ctatcaaaaa caactttgct gtagttgtag tggtaatgac cttggtcaat aatttcgcga
    38101 aaaaggccat ctttctttaa aatatctaat acagtttcaa tttttatcat actttctatt
    38161 gtaaaccgaa agtcgcaaat ttacaagtaa caaggaaaag tttataatgg aagataagga
    38221 gtttttccta gttatcaaaa ttgaatgagg aatctatgtc gcacgaaaac aatcaccagc
    38281 aggcccagat gttacggggg actgcttggc taacggctag taactttatc agtcgcctac
    38341 tcggggctgt ttacattatc ccttggtaca tatggatggg ggcttatgca gctaaggcaa
    38401 atggtctctt taccatgggt tacaatatct atgcttggtt cttgttggtt tcaacagcgg
    38461 ggattccagt tgcggtggcc aagcaagttg ccaagtataa taccatgcga gaagaagagc
    38521 atagctttgc cctgattcgg agcttcttag gctttatgac aggactaggc ctggtttttg
    38581 ctttagtctt gtatgtcttt gctccttggc tagcagactt gtctggcgtg ggcaaagact
    38641 tgatcccaat catgcaaagc ttggcttggg gagtcttgat tttcccgtct atgagtgtta
    38701 tccgaggatt tttccaaggg atgaataacc tcaaacctta tgccatgagc caaattgctg
    38761 agcaggtcat tcgtgttatc tggatgctcc tagcaacctt tatcattatg aagctcggtt
    38821 caggagatta tctagcagcc gttacccaat caacctttgc tgcctttgtc ggtatggtag
    38881 ccagttttgc agtcttgatt tatttccttg cccaagaagg ttcactcaaa agagtctttg
    38941 aaacaggaga taagattaac agtaagcgtc tcttggttga taccattaag gaagccattc
    39001 cttttatcct gacagggtct gccatccagc tcttccagat tttggatcag ctgaccttta
    39061 tcaatagtat gagctggttt accaactaca gcaatgagga cttggttgtc atgttttctt
    39121 atttctcagc caatcctaat aaaatcacga tgattttgat ttctgtaggg gtttcgattg
    39181 ggagtgttgg tttgccactt ttgacggaaa actatgtcaa gggggacttg aaagcagctt
    39241 ctcgtctcgt tcaggacagt ctcaccctac tctttatgtt cttgctacca gcaacggttg
    39301 gagtggttat ggtaggagaa cctctttata cggtcttcta tggtaagcca gatagtttgg
    39361 ctctgggctt atttgtcttt gcagttttgc agtctattat tttaggcttg tacatggtct
    39421 tgtctccaat gcttcaggcc atgttccgca accgcaaggc cgttctctat tttatctatg
    39481 gttctattgc caagctagtc ttgcaactac ctaccatcgc cctcttccac agttatggtc
    39541 ctttgatttc aacaaccatt gctctcatca ttcctaacgt cttgatgtat cgggatattt
    39601 gtaaagtaac tggtgtcaag cgcaaggtga ttttgaagcg aaccatttta atcggtttgc
    39661 tgaccctagt catgtttctg ttaataggaa ccatccagtg gctgttagga tttttcttcc
    39721 aaccaagtgg acgtttgtgg agcttctttt atgtagctct tgtcggtgcc atggggggtg
    39781 gactttatat ggttatgagt ctgcgtacct atttattaga taaggtaata ggaaaagccc
    39841 aagcagatcg cctgcgagca aaatttaagc tttcgtaagg tagcatttat aaataaaagg
    39901 aataagttga acaatctttt aggagaactt gaaacttatt ccttttttag cgtcaaaata
    39961 gctaaaatta tctttcaaaa atagaaaatg aggttttttt cgattttttg gaaaaaatca
    40021 ttgaataaac aaactaaatg ttgtacaata aaacaaatat ttaaagcagg aggttctgga
    40081 aatgaaaaag tctaagagca aatatctaac cttggcaggt cttgtcctgg gtacaggagt
    40141 tttattgagc gcgtgtggaa attctagcac ggcgtcaaaa acctacaact atgtttattc
    40201 aagtgatcca tctagcttga actatctagc agaaaaccgc gcagcaacat ccgatattgt
    40261 tgcaaatttg gtagacgggt tattagaaaa tgaccaatat gggaatatta ttccatcatt
    40321 agcagaggat tggactgttt ctcaggacgg tttgacttat acctacaaac ttcgtaagga
    40381 tgccaagtgg tttacttctg agggagaaga atatgcgcct gtaactgccc aggattttgt
    40441 gacaggtttg caatatgcag ctgataaaaa atcagaagcc ttgtatctag tgcaggactc
    40501 tgttgctggt ttggatgact atatcactgg taaaacaagc gacttttcaa ctgtcggtgt
    40561 caaggcactt gatgaccaaa cggttcaata tactttggtt aaaccagaac tttactggaa
    40621 ttcaaaaaca cttgcaacga tactttttcc tgttaatgca gatttcctga aatcaaaagg
    40681 ggatgatttt gggaaggcgg atccatctag tattttgtac aatggacctt tcttgatgaa
    40741 agcacttgtc tcaaaatctg ctattgaata taagaaaaac cctaattact gggatgctaa
    40801 gaatgtcttt gtagacgatg tgaaattgac ctactatgat ggtagcgacc aagaatcact
    40861 ggaacgtaat tttacagctg gtgcttatac tacggctcgt ctttttccta acagctccag
    40921 ctatgaaggg attaaagaaa aatacaaaaa caatatcatc tatagtatgc aaaattcaac
    40981 ttcatatttc tttaatttta acctagatag gaagtcttac aattatactt ctaaaacaag
    41041 tgacattgaa aagaaatcga ctcaggaagc agttctcaat aaaaacttcc gtcaggctat
    41101 caattttgct tttgacagaa catcttatgg ggctcagtct gaagggaaag aaggtgcaac
    41161 aaagattttg cgtaacctag tggttcctcc aaactttgtc agtatcaagg gaaaagactt
    41221 tggtgaagtt gtagcctcta agatggtcaa ctatggtaag gaatggcaag gtatcaactt
    41281 tgcggatggt caagaccctt actacaatcc tgagaaagcc aaggctaagt ttgcggaagc
    41341 taagaaagaa ctcgaagcaa aaggtgttca attcccaatc cacttggata agactgtgga
    41401 agtaacagat aaagtaggca tacaaggagt tagttctatc aaacaatcaa ttgaatctgt
    41461 tttaggttct gataatgtag tgattgacat tcagcaatta acatcagatg agtttgacag
    41521 ttcaggctac tttgctcaaa cagctgctca gaaagactat gatttatatc atggcggttg
    41581 gggacctgat tatcaagacc cgtcaaccta tctcgatatt tttaatacta atagtggagg
    41641 agttctacaa aatcttggac tagagcctgg agaagccaat gacaaggcta aggcagttgg
    41701 actggatgtc tatactcaaa tgttggaaga agctaataaa gagcaagatc cagccaaacg
    41761 ttatgagaaa tatgctgata ttcaagcttg gttgattgat agttctttag ttcttccaag
    41821 tgtttcgcgt gggggaacac catcattgag aagaaccgta ccatttgctg ctgcctatgg
    41881 tttaaccggt acaaaagggg ttgaatcata taaatacctc aaagtacaag ataagattgt
    41941 cacaacagac gaatatgcaa aagccagaga aaaatggttg aaagaaaaag aagaatccaa
    42001 taaaaaagcc caagaagaat tggcaaaaca tgtcaaataa aatctaattg tagataagtt
    42061 tgtgtaagaa gtctttgtgc ttaaaaacgc ataatatcag gtatataaaa tcctagatgt
    42121 tatgcgtttt gttataggaa gatttattag attttatcct caaattgagt tattcccgac
    42181 tttatccgtt gaaatattat aaggagtatt tatgaaatta aaattattaa gagtagatac
    42241 taaggtgatt atggggagtt tcttatttgt tctgtctagt ctacttgctt tgttgcttcc
    42301 ccttatctta aagggtttaa tagatgggag ttctattgaa aatataggtt tcaaagtatt
    42361 tcaatcgttt ttgattttta ttggtcaagc cttgttttct tctattggtt actatctgtt
    42421 tagtcaatcg ggtgaaaaaa gatagcaaaa atcaggaaaa aagtgataga ggggttgatt
    42481 tatgcagaga aatccttctt tgataagagc caaagtgggg agttgacttc tgccattgtc
    42541 aatgacatga gtgtcattcg tgagttttta attacgactt tcccaaatat tattctgagt
    42601 ttagttatgg tacttggttc cattgtagtc ttatttagtc ttgattggaa tctttctcta
    42661 cttttattca tcactcttcc ttgtatgatg tttattatct tgcccctttc caatatcagt
    42721 gaaaagtata gtcgtcgttt acaggaggaa atcggatttt taacagggca attgactgaa
    42781 aagattcaag aacatgaatt aattaagact aaccaagcag agaaaagtgt acaggatgtt
    42841 ttggataatt gtattgaaag ggtacaaaac aattcactga aatcagatag ggttacttct
    42901 tttgagaccc cgtttgctct cttatttatc tttgcgacta tagttgtgat gctaacctat
    42961 gggggttatc gggtcagcgc aggatatata tctgtgggaa ccttggtttc gtttttgatt
    43021 tacctctttc aattacttaa tcctattagt aatatagcta attttgtaac tatttattct
    43081 agtagcaagg gatcttcagt tgcactggag aacttgcttg cagttcctaa agaaaaattt
    43141 gagggaggaa aatcggtatc aggacgaggg ttgaatttta accatgtcta ttttggttat
    43201 gatgaaaatc gacctgtctt aaaggatatt atttgttcaa ttttcaaggg gcaaaaaatt
    43261 gcttttgttg gaccatctgg atcaggaaaa tcaacgattg tgcgtttgtt agagcggttt
    43321 tataaaccgc tttcaggaga tattctaatg gagcaatcaa gtatatatga ttttaactta
    43381 aaagaatgga gaagtaaaat cgcttgggtt tcacaaaata atgcagtctt atctggcagt
    43441 attcgtgaca atctttgtct cggtttgaat cgcttagtaa ctgatgatga attgatgaaa
    43501 gtgctagact tagtatcact aggtgatgag attcgctcca tgaaagaggg actagatact
    43561 gaagttggtg aacgcggacg actcttgtca ggggggcaaa gccaaagact tcaaatagct
    43621 agagcctact taaaagatgc tgaaattctt atatttgatg aagccactgc taatcttgat
    43681 gcggattctg agtatgcgat tatcagtagc ctctattctg tattaaagga gaagacggtt
    43741 gtgattatag cgcatcgttt gtcaacggta aaagatgtgg attgtatttt cttcttagag
    43801 gaggggaaaa tcactggctc aggaactcat aaggaactac tggaaaatca tgagcgttat
    43861 gctcgttttg tgcaggagca aatgatagag tgaaggtgtc ttttgagatt caccatttta
    43921 tagtctatta aagggagcag gaaaaactcc ctttttatat agtttgaaac tataactagc
    43981 tcttgaaaag aagaaaatga gttgatgaaa ataagtggta caatagttac tatagatttg
    44041 gaggtattgt atgagcaagg aattacacat taacacaatt ttggcccagg cgggtattaa
    44101 gtcagatgaa gcgacaggtg cattggtgac accgcttcat ttttcaacga cctatcagca
    44161 tccagagttt ggtcgatcta ctgggtttga ctatacgcgc actaaaaatc caactcgtag
    44221 taaggctgag gaagtcttgg cggctattga gtcagcagac tatgccttag cgactagctc
    44281 agggatgtca gctattgtac tggcctttag cgtctttcca gtaggaagta aggtcttggc
    44341 agtgcgtgat ctttacggtg gttcttttcg ctggtttaac caagtggagc aggaaggtcg
    44401 tttccatttt acctatgcca atacagaaga agagttgatt gccgagttag aaaaggatgt
    44461 ggatgttctc tatatcgaaa ccccaaccaa tcccttgatg ttggaatttg atatcgaaaa
    44521 actagcaaaa ttggctcatg ctaagggtgc caaagtggtg gtggacaata ccttctatag
    44581 ccctatctac caacgtccga ttgaagatgg agcagatatc gttctccatt cagcaaccaa
    44641 gtatctagca ggccacaatg atgtcttggc tggagtggtt gtgaccaata gtttagaact
    44701 atacgagaag cttttttaca atctcaatac aacaggggca gtcttgtctc catttgacag
    44761 ctaccagttg cttcgtggtc tcaagacctt gtctcttcgt atggagcgct caacagctaa
    44821 cgcccaagaa gtggttgcct ttttgaagga ttctccagca gttaaggaag ttctctacac
    44881 tggtcgtgga ggcatgattt cctttaaagt agccgatgaa acacgcattc ctcatatttt
    44941 gaacagtctc aaggtcttct cttttgcgga aagtttgggc ggagtggaaa gtcttattac
    45001 ttatccaacg actcaaactc atgctgatat tccagcagaa gtacgccatt cttatggttt
    45061 gacagatgac ctcttgcgtt tgtctattgg gattgaggat gctagagatt tgattgcaga
    45121 tttgcgccaa gccttagaag gataagacaa agatgggaaa atatgatttt acaagcctgc
    45181 ccaaccgttt agggcaccat acctataaat ggaaagaaac agaaacggat agtgaagttc
    45241 taccagcttg gatagcggat atggactttg tggtcttgcc tgaaatccgc caagccgtgc
    45301 aaacttacgc agaccaactg gtttatggtt atacctatgc cagtgaagac ttaattaagg
    45361 aagttcaaaa gtgggaagct acacaatacg gttacaactt tgacaaagag gctcttgtct
    45421 ttatcgaggg tgtggtacca gccatctcaa cagctattca aacctttaca aaagaaggcg
    45481 aggcggtttt aattaacacg cctgtctacc caccctttgc tcgcagtgtc aagttgaata
    45541 atcgtagatt gattactaat tccttagtgg aaaaggatgg tctgtttgag attgactttg
    45601 accaacttga aaaggatttg gtggaagagg aggttaaact ctatattctt tgcaaccctc
    45661 acaatcctgg tggacgtgtt tgggaaaaag aagtgttgga gaagattggc caactctgcc
    45721 aaaaacacgg tgttttgtta gtttcggatg agattcacca agatttgacc ctctttggtc
    45781 acaaacacca gtctttcaat accatcaatc ctgccttcaa aaattttgct atcgtcttga
    45841 gcagtgccac taaaacattt aatattgctg gaacaaaaaa ttcctatgca gtcattgaaa
    45901 atcctaagtt gagactggct ttccagaaac gcctgttggc caataatcag catgaaattt
    45961 caggcttggg ttatttggcg acagaagctg cctatcgata cggtaaagat tggctagagg
    46021 aactcaagca agtctttgaa gaccacatca attatgtggt ggatctattt ggaaaagaga
    46081 ctaaaatcaa ggtcatgaaa ccgcaaggta cctacttgat ttggcttgac ttttcagcct
    46141 atgacctgac tgatgaaaca ttgcaagagt tgttgagaaa tgaagccaag gttatcctca
    46201 accgtggttt ggattttgga gaggaaggaa gtctccattc ccgcatcaat atagctatgc
    46261 ccaaatctct gttgcaagaa gtctgtcagc ggattgtggc tacttttgcc aaacgttaaa
    46321 aatccagcct tctaggagaa aagtcttcct agaaggctat tttcataggc gaaaatatgg
    46381 tataataaac agataaggta aaggtgaaaa tatggctaaa ttgattccgg ggaaagttcg
    46441 tatcgaaggt gttgcccttt atgaaactgg taaggttgat atcatcaagg aaaagaacaa
    46501 tcggctctac gctcgcgttg cagaagaaga actgcgctat agtttagagg atgatttggt
    46561 tttttgtgcc tgtgattctt ttcaaaagag gggctactgt gtgcatttgg cagcgctaga
    46621 gcattttctg aaaaatgatg agcgtggtca ggaaatcttg tggagtctgg aagaaggtca
    46681 tgaagaaaaa gaggccgttg aaaccaaggt gaccttgggt ggcaagtttt tgaatcgaat
    46741 tttatctccg aaatcagaat gcgcctatga gttatcagct gtgggtcagg tggaagcagg
    46801 aaccaatcat atcttgtgga ctctgagaat cggccaaatc aatagacaaa aatactatgt
    46861 cattcgggat attccacttt ttttaaggat tgtcgagcag agaaagtcgt atatgattgg
    46921 caagatttat gaggagtctc tttcttggga agcctttgat gatgccagcc aagaactttt
    46981 gactttcttg cacggactaa cggaggaagg gctggttcca gacctctttt tccaaaacca
    47041 aggtcggcac ctctttttcc ctctgacctt ttttgagcag ggtgtgaatt tactgatggc
    47101 cttgccccat tttcaatttg accatcaagt ggatagctac caaaccctgc tttttcagga
    47161 tatgcatgct gataccaatc tatttgcctt tacagtaaca gaatactcgg actattttga
    47221 aatggaaatc agtgagagtc ctagggtcaa tgtcttttat cagggagcag tacttttcca
    47281 taaaggtcag gtttattttt taacagacca gcagatgcgt cttctcaagg aaattaaagt
    47341 gttacctgtg ggtcaacaag gaaagaaata cctgcaattt gatagcagtg atcgagacaa
    47401 attggcctcc tgtctgactc tttttatcca gatgggcacc gtttcagctc cagaacgtct
    47461 acaaatcaaa acttttgcgc cctcttttta ctttgacagg gaagaagata atcggattcg
    47521 tttagaaatt cagtttgatt atggaaatag acaggtatct agccgacaag agctagaaga
    47581 attaccattt tcaagtgacg cggacttaga agaaagaatt ttccaagtct gtttggctgc
    47641 gggctttgaa gccgattttc aatcttggcg tcaggcctta aaagcggagt ctgtctatca
    47701 tttttttcat gatatcattc cagtctttga aaaactcggg catgttgacc tatcagataa
    47761 actagaagag ctttatagcc tagcgagccc tcaggtgcag attgcctcca agggaggtct
    47821 cttggaaatc cagtttgatt ttcaagatat tgcccaggag gaaatcgacc aagccatgca
    47881 ggccttggtt gccaatcagg atttttatat tgattcgtct aatcaagttt actttttcga
    47941 tgaagaaacc aagaaaattc gccaaaatct acaggaactg gggcaatttg aattaaaaga
    48001 tgggaccttg caggctcgga aatccttggc ctacagttta gctcatctct ttgaagggcg
    48061 agaccgtgtt tctttttcac aagaattcca gaatctggcc caggatttga cgcatccaga
    48121 ggactttcct ttgcaagcaa ctcaggtcaa ggctgacttg cgagattatc aggaaaaggg
    48181 aattggctgg ttgcagatgc tccatcatta tggttttggt gggattttgg ctgatgatat
    48241 gggacttggg aaaacccttc agaccattgc ttttttgact agtcaagtga caaaagaaag
    48301 tcgagtcttg attctcgctc cgtcgggttt gatttacaac tgggcggatg agtttcagaa
    48361 atttgcccca cagttggatg tggctgttgt tcatggtttg aaagcaagtc gtgaggagat
    48421 tcttgccgag agccatcaaa tctatgtgac tagctatgcc accttccgtc aggacagtga
    48481 gctttatcag gagatggcct ttgacttcct tttcttagat gaagctcagg tcatgaaaaa
    48541 tgcccagacc aagattgccc agaccttgag acaatttgtg gtgccgtcgg tctttgcctt
    48601 gtcaggaact ccgattgaaa accatctggg tgagttgtgg tctattttcc aaatcgtcat
    48661 gcccggactt ttgccaagca agaaagaatt tatgaaattg ccagcagagc gagtggctca
    48721 gtttatcaag cctttcgtga tgcgacgcaa gaaagaagaa gttctgactg aattgccaga
    48781 cttgattgag gtggtttata aaaatgaact ggaagaccag caaaaggcta tttaccttgc
    48841 ccagttacaa cagatgcgag accatctggc tcaagtgtca gaacaggaat ttcagcgaag
    48901 tcgtgtggaa attttatctg gtttgatgcg cttgcgtcaa atatgtgaca ctcctgccct
    48961 gtttatggaa gattatcagg gagccagcgg caaactagat agtctccgag acctactggt
    49021 acaggtggca gacggcggac accgtgtctt gattttctct cagttcaagg gaatgttgga
    49081 aaaaattgaa caagaactgc cagacttggg cctgacatcc tttaaaatta cgggttcaac
    49141 cccagccaag gaaagacaag acatgaccaa ggcctttaac caaggagaaa gagatgcctt
    49201 tctgatttcc ctcaaggctg gtggggtcgg tctgaacctg acaggtgcag atacagtgat
    49261 cttggttgac ctttggtgga atcctgcggt ggaagcgcaa gccattggcc gtgcccatcg
    49321 gatgggtcag gaagaaacgg ttgaggtcta tcgcttggtg accaagggaa ccattgaaga
    49381 aaaaattcag gaactccaag aacaaaagaa acatctggtg tcacaagtat tggatggcac
    49441 agagtcacgt ggtagtctga ccctagcaga aattagagaa attttgggaa tttctgaagc
    49501 cagcacttga aaaatcaaga caatacgcta taatgaagtg ttgaaaggaa atagaaaatg
    49561 aaacaagaac gatttccatt ggtgtcagat gacgaggtca tgttgactga aatgccagtc
    49621 atgaatctct atgatgagtc tgatctgatc agtaatatca agggtgagta tcgagataaa
    49681 aattatttag aatgggctcc tattactgaa gaaaaaccag taaaaccgat tgaaaagcaa
    49741 gtcgaaaaac ctaaaaaggc tcctttaggg gttaaaaaag aaggaaagag ctatgcggag
    49801 gtggcgcgtg aagaagcgcg tgcggacttg aaaaagaaac gctctgctaa ctacctaact
    49861 caggatttca gccttgcgag acgtcattct cagcccagtc tagttagaca gggcaatcaa
    49921 ccgacaactc ctttccaaaa ggaaaatcct ggtgaatttg tcaaatatag ccaaaaattg
    49981 acccagtctc attatatctt ggcggaagaa gttcattcta tccctaccaa gaatgaagaa
    50041 gtgtcagcac ctgctccaaa gaaaaacaat tatgattttc taaagaagag ccaaatctac
    50101 aataaaaaaa gtaaacaaac agaacaagaa cgtcgggttg cccaagagtt gaatctgacc
    50161 agaatgacag aataggggag aaaacatgtc aaagacatat cattttatcg gaattaaggg
    50221 atcagggatg agtgccttgg ccttgatgtt gcaccagatg gggcacaagg ttcagggatc
    50281 agatgttgaa aagtactact ttacccaacg cggtcttgag caggcaggaa ttaccattct
    50341 tccttttgat gaaaagaatc tagacggtga tatggaaatt atcgctggaa atgcctttcg
    50401 tccagataac aacgtcgaaa ttgcctatgc ggaccaaaat ggtatcagct acaaacgtta
    50461 ccatgagttt ctaggtagct ttatgcgtga ctttgttagc atgggagtag caggagcaca
    50521 tggaaaaact tcaacgacag gtatgttgtc tcatgtcttg tctcacatta cagataccag
    50581 cttcttgatt ggagatggga caggtcgtgg ttcggctaat gccaaatatt ttgtctttga
    50641 atctgacgaa tatgagcgtc acttcatgcc ttaccaccca gaatactcta ttatcaccaa
    50701 cattgacttt gaccatccag attatttcac aagtctcgag gatgttttca atgcctttaa
    50761 cgactatgcc aaacaaatta ccaagggtct ttttgtctat ggtgaagatg ctgaattgcg
    50821 taagattacg tctgatgcac caatttatta ttatggtttt gaagctgaag gcaatgactt
    50881 tgtagctagt gatcttcttc gttcaacaac tggttcaacc ttcaccgttc atttccgtgg
    50941 acaaaacttg gggcaattcc acattccaac ctttggtcgt cacaatatca tgaatgcgac
    51001 agccgttatt ggtcttcttt acacagcagg atttgatttg aacttggtgc gtgagcactt
    51061 gaaaacattt gccggtgtta aacgtcgttt cactgagaaa attgtcaatg atacagtgat
    51121 tattgatgac tttgcccatc atccaacaga aattattgcg accttggatg cggctcgtca
    51181 gaaataccca agcaaggaaa ttgtagcagt ctttcaaccg cataccttta caagaaccat
    51241 tgccctgttg gacgactttg cccatgcttt aaaccaagca gatgctgttt atctagcgca
    51301 aatttatggc tcggctcgtg aagtagatca tggtgacgtt aaggtagaag acctagccaa
    51361 taaaatcaac aaaaaacacc aagtgattac tgttgaaaat gtttctccac tcctagacca
    51421 tgacaatgct gtttacgtct ttatgggagc aggagacatc caaacctatg aatactcatt
    51481 tgagcgtctc ttgtctaact tgacaagcaa tgttcaatag gatgttccca tggaaattcc
    51541 aattaagatc attcaggcaa gcaagtttga tttgcctgag ataggggcac ttcagacctc
    51601 gtcttttcca gctgaaaagc agcaactttc ccatatttta gaagaaagta tccgtaagtg
    51661 tgcggatacc tttcttctag ctagggatga aaatcaactt ttaggctata ttttatcaag
    51721 tccccagtca gacaatccgc aatgtctaaa agtacattct ttagtcatcg agtctgacca
    51781 tcagagacag ggcctgggaa cacttcttct tgcagccttg aaagaggtgg cagttgagct
    51841 ggattacaaa gggattcgtt tggagagtcc tgatgagctg ctttcctatt ttgaaatgaa
    51901 cggttttgtt gatgaagaag aaactttgct ctatgcaact agccagggct atagtatgat
    51961 ttggtttaat cccttttatc tggaggaaca atgaaaatca gacaagcaag attagaagat
    52021 ttggatcgga ttgttgaact tgaatttgaa aatttttcgg tcgaagaagc cattcctcct
    52081 tctgtctttg aagcacattt gagagaaatt cagacctctt ttctggttgc tgaaaaagaa
    52141 ggaagaatca tgggttatat cgaaggacca gttggcctgc accgccatct gcaagaccag
    52201 tcttttacag aagaaataaa agactatagt catgagcctg gtggttatat ctctgtgacc
    52261 tgtctgtcta ttgccaagga ggcacaggga ctcggactgg gtcagaaatt gctgacagcc
    52321 ttgaaagaag ttgctcttga agatgagaga gatggcatta atctaacctg tcatgactat
    52381 ctcatcgcct attatgaaaa acatggattt gtcaacgaag gccagtccca gtcaaccttt
    52441 gcaggggaaa catggtatga tatggtctgg gaaatgaaaa aataagttag gaaaagtatc
    52501 atagattgct ttttttggac ttttaagata taatattatg gattatcaac aaggaggaaa
    52561 aacttttgag tgaaaagtca agagaagaag agaaattaag ctttaaagag cagattctga
    52621 gagatttaga aaaagtaaaa ggctatgatg aagttctgaa agaagatgag gcagtagttc
    52681 gcactcctgc aaatgaacct tcagctgaag aactcatggc tgattccttg tcaacggtag
    52741 aggagattat gagaaaagct cctaccgtgc ctactcaccc aagtcaaggt gtaccagctt
    52801 ctccagcaga tgagattcaa agagaaactc ctggtgttcc aagtcatcca agtcaagatg
    52861 taccttcttc tccagcggaa gaaagtggat caagaccagg tccaggtcct gttagaccta
    52921 agaaacttga aagagaatac aatgaaaccc caacaagggt agctgtttcc tatacgacgg
    52981 cagagaaaaa agcagaacaa gcaggtccag aaacacctac gcctgctaca gaaacagtgg
    53041 atatcatcag agatacatca cgtcgtagcc gtagagaagg agcaaaaccc gttaagccta
    53101 agaaagagaa gaagtcacat gtgaaagctt ttgtgatttc attccttgta ttccttgcct
    53161 tgctctcagc aggtggttac tttggttacc agtacgtgct agattcctta ttacctatcg
    53221 atgctaattc taagaaatat gtgacggttg gaattccaga aggttcaaac gttcaagaaa
    53281 tcggtacgac gcttgaaaaa gctggtttgg taaagcatgg tctgattttt agtttttatg
    53341 ccaagtataa aaattatacc gacttgaaag caggttacta caatttgcaa aagagtatga
    53401 gtacagaaga cttactcaaa gagttgcaaa aaggtggaac agatgaaccg caagaacctg
    53461 tacttgcgac tttgacaatt ccagaaggtt ataccttgga tcagattgct caaactgtgg
    53521 gtcaattgca aggtgacttc aaagagtctt tgacagcgga ggctttcttg gctaaagttc
    53581 aagatgagac gtttatcagt caagcagtag cgaaatatcc tactttactg gaaagtttgc
    53641 ctgtaaaaga cagcggtgcg cgttatcgtt tggaaggata ccttttccca gctacatact
    53701 ctatcaagga aagcacaact attgagagct tgattgatga gatgttagct gctatggata
    53761 agaacctatc tccttactat agtactatca aatctaaaaa cttgactgtc aatgagttgt
    53821 tgaccattgc ttccttggtc gaaaaagaag gtgccaagac agaagatcgt aagctcattg
    53881 caggtgtatt ctacaatcgt ttgaatcgtg atatgccact tcaaagtaat attgcaatct
    53941 tgtatgccca aggaaaactg gggcaaaata tcagtctagc tgaggatgtt gcgattgata
    54001 ccaacattga ttcaccttat aatgtttata aaaatgtagg tctcatgcct ggtccagtcg
    54061 atagtccaag tctggatgcg attgagtcaa gcatcaatca aactaagagc gataacctct
    54121 actttgtagc agatgtcaca gaaggcaagg tctactatgc taacaatcaa gaagaccacg
    54181 accgcaatgt cgctgaacat gtcaacagca aattaaacta aacaaactaa aattatgtga
    54241 tacttcacat aattttcttt agaaaatatt atcagaagaa agttgagaaa aatggcagaa
    54301 aaaacatatc ctatgaccct tgaggaaaag gaaaaacttg aaaaagaatt agaagaattg
    54361 aaattggttc gtcgaccaga agtggtagaa cgcattaaga ttgcccgttc atacggtgac
    54421 ctttcagaaa acagtgagta cgaagcagct aaggatgaac aagcctttgt cgaaggacaa
    54481 atctctagct tagaaacaaa aatccgctat gctgaaatcg tcaatagcga cgcagttgcc
    54541 caggacgaag tagcgattgg taaaacagtc accatccaag aaattggtga ggacgaagaa
    54601 gaagtttata ttatcgtagg ttcagctggt gcggatgcct ttgcaggtaa ggtttcaaat
    54661 gaaagcccaa ttgggcaggc cttgattggc aagaaaacag gtgatacagc aaccattgaa
    54721 acgcctgttg gtagctatga tgtaaaaatc ttgaaggttg aaaaaacagc ctaaaaacag
    54781 aaaaaggagt ggggaggcga tgtgcttcac tcactccttt ttccattttg ctactcttcg
    54841 aaaatctctt caaaccacgt cagcgtcgcc ttgccgtatg tatggttact gacttcgtca
    54901 gtttcatcta caacctcaaa acagtgtttt gagcaacctg cggctagttt cctagtttgc
    54961 tctttgattt ttattgagta ttagatgtat agtgcattga agttaaaata gtacactttg
    55021 atttctaaga cattgttaga aattagatta aattccttaa tcgatttgcg catgttttat
    55081 ttcatttcac tatactttag attggaaaat aaggaatcac ataaatcgca agaaataggg
    55141 aatctgattc gtgtttataa ccgttcaaaa agagaagagg ctgaaagtga gccacttaat
    55201 ctttatgtcg aagatgaaaa gggcaatctc ctggcaggtt tgatagcaga gacttttgga
    55261 aattggctag aaatcgagta tttgtttgta aaagaggaac tgcgagggca aggaatcggt
    55321 tcaaaactat tgcaacaggc agaaagtgaa gctaagaatc gaaattgttg ttttgccttt
    55381 gtcaatactt accagttcca ggcaccggac ttttatcaga aacatggcta caaggaagtt
    55441 ttttctttgc aagactatct ctacattagg caaagatatt attaccaaaa gaatctgtaa
    55501 ggtgagtatg gaggtataat acaaagagag gctcgcacat aagtatggag gtggactgat
    55561 gtatatgagt aactattgat aaataccagt tataacctag aaattgtgtc tttctagacg
    55621 atattgagga caatataatc gtagccccaa aattaggaat caagacttat caggttaaga
    55681 aaagaagtga tgttgttgat attttaaaca atttatttaa actaaaaact ctctatctat
    55741 taatccgaga ttcccctctc ggattttgtg ttgctttcat taaatttaca ggtaagactt
    55801 gctagcttca gtaaatatac acaagttttt cagaatagag tgaaatccaa aagaaaatgg
    55861 aaataatga
//
LOCUS       DAVDFK010000013        48624 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.13, whole genome shotgun sequence.
ACCESSION   DAVDFK010000013 DAVDFK010000000
VERSION     DAVDFK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.13"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            3..75
                     /locus_tag="VUR04_000921"
     tRNA            3..75
                     /locus_tag="VUR04_000921"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VUR04_000922"
     tRNA            81..151
                     /locus_tag="VUR04_000922"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VUR04_000923"
     tRNA            186..259
                     /locus_tag="VUR04_000923"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VUR04_000924"
     tRNA            342..431
                     /locus_tag="VUR04_000924"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            442..515
                     /locus_tag="VUR04_000925"
     tRNA            442..515
                     /locus_tag="VUR04_000925"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Met,seq:cat)
     gene            519..591
                     /locus_tag="VUR04_000926"
     tRNA            519..591
                     /locus_tag="VUR04_000926"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:552..554,aa:Phe,seq:gaa)
     gene            604..684
                     /locus_tag="VUR04_000927"
     tRNA            604..684
                     /locus_tag="VUR04_000927"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:638..640,aa:Tyr,seq:gta)
     gene            689..759
                     /locus_tag="VUR04_000928"
     tRNA            689..759
                     /locus_tag="VUR04_000928"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:721..723,aa:Trp,seq:cca)
     gene            774..846
                     /locus_tag="VUR04_000929"
     tRNA            774..846
                     /locus_tag="VUR04_000929"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:807..809,aa:His,seq:gtg)
     gene            860..931
                     /locus_tag="VUR04_000930"
     tRNA            860..931
                     /locus_tag="VUR04_000930"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:892..894,aa:Gln,seq:ttg)
     gene            941..1024
                     /locus_tag="VUR04_000931"
     tRNA            941..1024
                     /locus_tag="VUR04_000931"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:975..977,aa:Leu,seq:caa)
     gene            1131..2408
                     /locus_tag="VUR04_000932"
     CDS             1131..2408
                     /locus_tag="VUR04_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET5340845.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2484..3968
                     /locus_tag="VUR04_000933"
     CDS             2484..3968
                     /locus_tag="VUR04_000933"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET5340846.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCESYS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            4029..5309
                     /locus_tag="VUR04_000934"
     CDS             4029..5309
                     /locus_tag="VUR04_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET5340847.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGITGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5313..5933
                     /locus_tag="VUR04_000935"
     CDS             5313..5933
                     /locus_tag="VUR04_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5340848.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6099..7241
                     /locus_tag="VUR04_000936"
     CDS             6099..7241
                     /locus_tag="VUR04_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET5340849.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7564..7989
                     /locus_tag="VUR04_000937"
     CDS             7564..7989
                     /locus_tag="VUR04_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET5340850.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            8000..8367
                     /locus_tag="VUR04_000938"
                     /pseudo
     CDS             8000..8367
                     /locus_tag="VUR04_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8474..9091
                     /gene="pcp"
                     /locus_tag="VUR04_000939"
                     /pseudo
     CDS             8474..9091
                     /gene="pcp"
                     /locus_tag="VUR04_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9119..9976)
                     /locus_tag="VUR04_000940"
     CDS             complement(9119..9976)
                     /locus_tag="VUR04_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET5340851.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10106..11248
                     /gene="tgt"
                     /locus_tag="VUR04_000941"
     CDS             10106..11248
                     /gene="tgt"
                     /locus_tag="VUR04_000941"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET5340852.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11349..13166
                     /locus_tag="VUR04_000942"
     CDS             11349..13166
                     /locus_tag="VUR04_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET5340853.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13319..14470
                     /gene="nagA"
                     /locus_tag="VUR04_000943"
     CDS             13319..14470
                     /gene="nagA"
                     /locus_tag="VUR04_000943"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET5340854.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14633..15691
                     /locus_tag="VUR04_000944"
     CDS             14633..15691
                     /locus_tag="VUR04_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET5340855.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLINGMQAEYLRVPHADNTLYHTPADLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETAVSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15842..16207
                     /locus_tag="VUR04_000945"
     CDS             15842..16207
                     /locus_tag="VUR04_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET5340856.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16283..17224
                     /locus_tag="VUR04_000946"
     CDS             16283..17224
                     /locus_tag="VUR04_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET5340857.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17172..18188
                     /locus_tag="VUR04_000947"
     CDS             17172..18188
                     /locus_tag="VUR04_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET5340858.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMIVFVSVGVLLALTFYKRSSKMRVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18190..18516
                     /gene="comGC"
                     /locus_tag="VUR04_000948"
     CDS             18190..18516
                     /gene="comGC"
                     /locus_tag="VUR04_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET5340859.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYHDKNGGA
                     NRKVND"
     gene            18509..18913
                     /locus_tag="VUR04_000949"
     CDS             18509..18913
                     /locus_tag="VUR04_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET5340860.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18918..19178
                     /locus_tag="VUR04_000950"
     CDS             18918..19178
                     /locus_tag="VUR04_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340861.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19141..19602
                     /locus_tag="VUR04_000951"
     CDS             19141..19602
                     /locus_tag="VUR04_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET5340862.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            19580..19993
                     /locus_tag="VUR04_000952"
     CDS             19580..19993
                     /locus_tag="VUR04_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET5340863.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20130..20724
                     /locus_tag="VUR04_000953"
                     /pseudo
     CDS             20130..20724
                     /locus_tag="VUR04_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20785..21738
                     /locus_tag="VUR04_000954"
     CDS             20785..21738
                     /locus_tag="VUR04_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5340864.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21789..22979
                     /locus_tag="VUR04_000955"
     CDS             21789..22979
                     /locus_tag="VUR04_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET5340865.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23128..23499
                     /gene="rnpA"
                     /locus_tag="VUR04_000956"
     CDS             23128..23499
                     /gene="rnpA"
                     /locus_tag="VUR04_000956"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET5340866.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23474..24298
                     /locus_tag="VUR04_000957"
     CDS             23474..24298
                     /locus_tag="VUR04_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET5340867.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24317..25303
                     /locus_tag="VUR04_000958"
     CDS             24317..25303
                     /locus_tag="VUR04_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET5340868.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25354..25977
                     /locus_tag="VUR04_000959"
     CDS             25354..25977
                     /locus_tag="VUR04_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET5340869.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26108..27565
                     /locus_tag="VUR04_000960"
     CDS             26108..27565
                     /locus_tag="VUR04_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5340870.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27588..27869
                     /locus_tag="VUR04_000961"
     CDS             27588..27869
                     /locus_tag="VUR04_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5340871.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27946..28431
                     /locus_tag="VUR04_000962"
     CDS             27946..28431
                     /locus_tag="VUR04_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5340872.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28448..29113
                     /locus_tag="VUR04_000963"
     CDS             28448..29113
                     /locus_tag="VUR04_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET5340873.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGTARAFKDEIKR
                     IWG"
     gene            29117..29980
                     /locus_tag="VUR04_000964"
     CDS             29117..29980
                     /locus_tag="VUR04_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET5340874.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEVFDILKETNYNGPFLIEMWSENCEIVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29982..30686
                     /locus_tag="VUR04_000965"
     CDS             29982..30686
                     /locus_tag="VUR04_000965"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET5340875.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNHFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30865..32538
                     /locus_tag="VUR04_000966"
     CDS             30865..32538
                     /locus_tag="VUR04_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5340876.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32650..33741
                     /gene="ulaG"
                     /locus_tag="VUR04_000967"
     CDS             32650..33741
                     /gene="ulaG"
                     /locus_tag="VUR04_000967"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET5340877.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33855..35831
                     /gene="tkt"
                     /locus_tag="VUR04_000968"
     CDS             33855..35831
                     /gene="tkt"
                     /locus_tag="VUR04_000968"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5340878.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35948..36247
                     /gene="yajC"
                     /locus_tag="VUR04_000969"
     CDS             35948..36247
                     /gene="yajC"
                     /locus_tag="VUR04_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET5340879.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36293..36721
                     /locus_tag="VUR04_000970"
     CDS             36293..36721
                     /locus_tag="VUR04_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET5340880.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36723..37133
                     /locus_tag="VUR04_000971"
     CDS             36723..37133
                     /locus_tag="VUR04_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340881.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37433..40084
                     /gene="adhE"
                     /locus_tag="VUR04_000972"
                     /gene_synonym="adhC"
     CDS             37433..40084
                     /gene="adhE"
                     /locus_tag="VUR04_000972"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET5340882.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRKLAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40881..41189)
                     /locus_tag="VUR04_000973"
     CDS             complement(40881..41189)
                     /locus_tag="VUR04_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5340883.1"
                     /translation="MTEEMEYICFQIIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(41186..41494)
                     /locus_tag="VUR04_000974"
     CDS             complement(41186..41494)
                     /locus_tag="VUR04_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5340884.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41499..42794)
                     /locus_tag="VUR04_000975"
     CDS             complement(41499..42794)
                     /locus_tag="VUR04_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5340885.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42812..44221)
                     /locus_tag="VUR04_000976"
     CDS             complement(42812..44221)
                     /locus_tag="VUR04_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET5340886.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            44379..45107
                     /locus_tag="VUR04_000977"
     CDS             44379..45107
                     /locus_tag="VUR04_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5340887.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45567..45761
                     /locus_tag="VUR04_000978"
     CDS             45567..45761
                     /locus_tag="VUR04_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5340888.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(46127..47437)
                     /locus_tag="VUR04_000979"
     CDS             complement(46127..47437)
                     /locus_tag="VUR04_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET5340889.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47674..48546
                     /locus_tag="VUR04_000980"
     CDS             47674..48546
                     /locus_tag="VUR04_000980"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET5340890.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT        14788 a         8683 c        10674 g        14479 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 gacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta acgcgggatg gagcagctcg gtagctcgtc gggctcataa
      481 cccgaaggtc gtaggttcaa atcctgctcc cgcaataagg ctcggtagct cagttggtag
      541 agcaatggat tgaagctcca tgtgtcggcg gttcgattcc gtctcgcgcc atttatatat
      601 tttggaaggg tagcgaagag gctaaacgcg gcggactgta aatccgctcc ttcgggttcg
      661 ggggttcgaa tccctcccct tccattttac gggcatagtt taaaggtaga actaaggtct
      721 ccaaaacctt cagtgtgggt tcaattccta ctgcccgtgt taatagaatt atggcgggtg
      781 tggtgaagtg gttaacacac cagattgtgg ctctggcatg cgtgggttcg atccccatca
      841 ctcgcctatt ttatattatt ggggtatagc caagcggtaa ggcaagggac tttgactccc
      901 tcatgcgttg gttcgaatcc agctacccca gttactattt gccggcgtgg cggaattggc
      961 agacgcgctg gactcaaaat ccagtgtccg caaggacgtg ccggttcgac cccggccgcc
     1021 ggtatagtat agtgttagga acgttgttat tcttcgttcc ttttttatat tatttttggt
     1081 ataattatag ttattcaaat tttatttaga ttgagaaagc gtagggtagt atgtcttgtt
     1141 ctatcgattt attaaaacac cggtatttga aaaatattaa agaaaatcct gaattgtttg
     1201 tcggaattga gttggagtat cctgttgcaa gtttagaagg ggatgctaca gatgttgaag
     1261 ttataaagga tctatttcat tatttagttt ctactttgga tctcaccgta gcaaaggtag
     1321 atgattttgg caatctgatc cagttagtag atccgataag tcaggatgct attttatttg
     1381 aagtttccta tacaacgatt gagtttgcat ttggtaaggc tgaaacgatt caagaggtcg
     1441 aaaatcgttt caataattat atgaatgtaa ttcagagaaa gttagctgaa tcaaatcatg
     1501 ctattgttgg ctgtggtatc catcccaact gggataaaaa tgagaattgt ccagtggctt
     1561 atccacgcta tcagatgttg atggattatt tgaatttgag tagaaatatt attaaatcag
     1621 atttacatca tttccctgaa tatggtactt ttatctgtgg gagccaggtt cagctggata
     1681 tttcaaaaac caactactta cgggtgatta atgcttttac tcaaattgaa gcggctaagg
     1741 cttatttatt tgcaaactct gagttttcgg gtgcggattg ggatacgaaa atttcaaggg
     1801 atattttctg ggaagaatct atgcatggta tctatccaga gaatgttggg gtcaatgcta
     1861 gactccttaa tgatgaagct gatttttttg actatctaaa tcattctgcg atttttactg
     1921 cggaacgtga tgggcagacc tattattttt atcctattca ggctggggac tatttggcta
     1981 cgcctgaaat ccaagcattt gctctgaatg gggatgaggt tattatttcc ccccaagaga
     2041 aggattttga aactcatcgt agttaccagt accaagactt aacgactcga ggaacagttg
     2101 agtttcgtag tgtgtgtaca cagccacttg ataggacttt tgcttctgca gcttttcact
     2161 tgggattatt ggttaattta gacaagttag aagcttactt agaaacagca cctttcttta
     2221 aagtatttgg ttatgattac aagtttttaa ggagacaatt ttctaagaaa aatcttacag
     2281 atgaggaaga aactacgatt attgaatttt ccaaagactt actcctacta gctgaggagg
     2341 gactagtggt gagaaataag gaagaaatga cctatttaca gcctttgaga gaagaattga
     2401 gcctataatt tctcttataa agggagaatt ttctgaaaaa tcatgatata atggacgaga
     2461 ctatagataa aggatagaga gtaatgacat tagtttatca atcaacgcgt gatgccaaca
     2521 atacagtaac tgccagccaa gcaattttgc aaggtttggc gacggacggc ggtttgttta
     2581 caccggttac ttatccaaag gtagatttgg actttgacaa attgaaagat gcttcttatc
     2641 aggaagttgc taagctagtt ttgtcagcat ttttagatga ctttacagct gaggagttgg
     2701 actactgtat caacaatgcc tacgatagca aatttgatac tccagctatt gcaccattag
     2761 tgaaattaga tgggcaatac aatttggaac ttttccatgg ttcaacgatt gcctttaagg
     2821 atatggcctt gtctattttg ccatacttta tgacgactgc tgctaagaaa catggtttgg
     2881 agaacaagat tgttatcttg acagcgacat ctggtgacac ggggaaagct gctatggcgg
     2941 ggtttgcgga tgtgcctggt actgagatta tcgtctttta tccaaagggt ggtgtcagca
     3001 aggtacaaga gttgcaaatg accactcaga atggtgacaa tactcatgtt atcgctatag
     3061 atggtaactt tgacgatgcg caaaccaacg tgaagcacat gtttaacgac gtggctcttc
     3121 gtgaaagatt agcggccaac aagttgcaat tttcatctgc taactctatg aatatcggtc
     3181 gtttggtgcc acagattgtt tattatgttt atgcctatgc tcagttggtc aagactggtg
     3241 agatcgtggc tggtgataag attaacttca cagtaccaac aggaaacttt ggaaatatct
     3301 tggctgcctt ttatgccaaa caaatcggtc tcccagttgg taaattgatc tgtgcttcaa
     3361 atgacaacaa tgttttgaca gacttcttta aaacacgtgt ctatgataaa aaacgtgagt
     3421 ttaaggtaac aaccagccca tctatggata tcttggtatc ttcaaacttg gagcgcttga
     3481 ttttccatct tttgggaaat aatgctgaaa agacagctga actcatgaat gctttgaaca
     3541 tgcaaggaca atataagttg acagactttg atgcagagat tttggacctc tttgcagctg
     3601 aatatgcgac tgaggaagaa acggcagcag agatcaagcg tgtttgtgag tcatattctt
     3661 atatcgagga ccctcataca gctgttgctt cagcagttta taaaaaatac caatcggcca
     3721 ctggagatgt aactaagaca gtgattgctt caacagctag tccatacaag ttcccagtag
     3781 ttgcagtaga agctgtaact ggaaaagcag gtttaacaga ctttgaagcc ttggctcaat
     3841 tacatgaaat ctcaggcgtt gcagtgccac cagcagttga tgggcttgag acagctcctg
     3901 ttcgtcacaa gacaactgta gcggctgctg atatgcaagc agcggttgag gcttatttag
     3961 gactttaaga tagagggagt aaactcggtt gggaaaccaa ctgagtttct tttcatcagg
     4021 aggagagatt gtttaagaaa aataaagaca ttcttaatat tgcattgcca gctatgggtg
     4081 aaaacttttt gcagatgcta atgggaatgg tggacagtta tttggttgct catttaggat
     4141 tgatagctat ttcaggggtt tcagtagctg gtaatattat caccatttat caggcgatct
     4201 tcatcgctct gggagctgct atttccagtg ttatttcaaa aagcataggg cagaaagacc
     4261 agtcgaagtt ggcctatcat gtgactgagg cgttgaagat taccttacta ttaagtttcc
     4321 ttttaggatt tttgtccatc ttcgctggga aagagatgat aggacttttg gggacggaga
     4381 gggatgtagc tgagagtggt ggactgtatc tatctttggt aggcggatcg attgttctct
     4441 taggtttaat gactagtttg ggagccttga ttcgtgcaac gcataatcca cgtctgcctc
     4501 tctatgttag ttttttatcc aatgccttga atattctttt ttcaagtcta gctatttttg
     4561 ttctggatat ggggataact ggtgttgctt gggggacaat tctgtctcgt ttggttggtc
     4621 ttgtgatttt gtggtcacaa ttaaaactgc cttatgggaa gctaactttt ggtttagata
     4681 aggaactgtt gaccttggct ttaccagcag ctggagagcg acttatgatg agggctggag
     4741 atgtagtgat cattgccttg gtcgtttctt ttgggacgga ggcagttgct gggaatgcaa
     4801 tcggagaagt cttgacccag tttaactata tgcctgcctt tggcgtcgct acggcaacgg
     4861 tcatgctgtt ggcccgagca gttggagagg atgattggaa aagagtcgct agtttgagta
     4921 aacaaacctt ttggctttct ctgttcctca tgttgcccct gtcctttagt atatatgtct
     4981 tgggtgtacc attaactcat ctctatacga ctgattctct agcggtggag gctagtgttc
     5041 tagtgacact gttttcacta cttggaaccc ctatgacgac aggaacagtc atctatacgg
     5101 cagtctggca gggattagga aatgcacgcc tcccttttta tgcgacaagt ataggcatgt
     5161 ggtgtatccg cattggaaca ggatatctgc tggggattgt gcttggttgg ggcttgcctg
     5221 gtatttgggc agggtctctc ttggataatg gttttcgctg gttatttcta cgctatcgtt
     5281 accagcgcta tatgagcttg aaaggatagg aaatgcaaaa aacagctttt atttgggatt
     5341 tagacgggac tttattggac tcttacgaag cgattttatc agggattgag gagacttttg
     5401 ctcagttttc tattccttat gataaggaga aggtgagaga gtttatcttc aagtattcgg
     5461 tgcaagattt gcttgtgcgg gtggcagaag atagaaatct ggatgttgag gtgctaaatc
     5521 aggtgcgtgc ccagagtctg gctgagaaga atgctcaggt agttttgatg ccaggtgcgc
     5581 gtgaggtgct agcttgggca gacgaatcag gaattcagca gtttatatat actcataagg
     5641 ggaacaacgc ttttaccatt ctcaaggact tgggggtgga atcctatttt acagagattt
     5701 taaccagtca gagtggcttt gtgcggaagc caagtccaga agcggctacc tatctgctag
     5761 ataagtatca gttgaattct gataatactt attatatagg ggatcggact ctggatgtgg
     5821 aatttgccca gaatagtggg attcaaagta tcaacttttt agagtctact tatgaaggga
     5881 atcacaggat tcaagcgtta gcagatattt cccgtatttt tgagactaag tgataaaaag
     5941 attgtgtcag ttttgtgaca gagacctaac aaactatttc aagtaaccta gtttgttaca
     6001 aggaatagac agttctgtta aataggcccg agagggcttt ttttctacat tttttgtgtt
     6061 atcatagaca ggtactcatt tgaaaggaat ttgaaagaat gaagaaaaga atgttattag
     6121 cgtcaacagt agccttgtca tttgccccag tattggcaac tcaagcagaa gaagttcttt
     6181 ggactgcacg tagtgttgag caaatccaaa acgatttgac taaaacggac aacaaaacaa
     6241 gttataccgt acagtatggt gatactttga gcaccattgc agaagccttg ggtgtagatg
     6301 tcacagtgct tgcgaatctg aacaaaatca ctaatatgga cttgattttc ccagaaactg
     6361 ttttgacaac gactgtcaat gaagcagaag aagtaacaga agttgaaatc caaacacctc
     6421 aagcagactc tagtgaagaa gtgacaactg cgacagcaga tttgaccact aatcaagtga
     6481 ccgttgatga tcaaactgtt caggttgcag acctttctca accaattgca gaagctccaa
     6541 aagaagtagc atcaagttca gaagttacaa agacagtgat tgcttctgaa gaagtggcac
     6601 catctacggg cacttctgtc ccagaggagc aaacggccga aacaagcagt gcagttgcag
     6661 aagaagctcc tcaggaaacg actccagctg agaagcagga aacacaagca agccctcaag
     6721 ctgcatcagc agtggaagca actacaacaa gttcagaagc aaaagaagta gcatcatcca
     6781 atggagctac agcagcagtt tctacttatc aaccagaaga gacgaaagta atttcaacaa
     6841 cttacgaggc tccagctgcg cccgattatg ctggacttgc agtagcaaaa tctgaaaatg
     6901 caggtcttca accacaaaca gctgccttta aagaagaaat tgctaacttg tttggcatta
     6961 catcctttag tggttatcgt ccaggagaca gtggagatca cggaaaaggt ttggctatcg
     7021 actttatggt accagaacgt tcagaattag gggataagat tgcggaatat gctattcaaa
     7081 atatggccag ccgtggcatt agttacatca tctggaaaca acgtttctat gctccattcg
     7141 atagcaaata tgggccagct aacacttgga acccaatgcc agaccgtggt agtgtgacag
     7201 aaaatcacta tgatcacgtt cacgtttcaa tgaatggata aacccgactt gataacatca
     7261 ttttgacgaa tgagatctag ctttcgtgat ggaaagcgat tctcgttcgt tttttctttg
     7321 tcatactctt cgaaaatctc ttcaaaccac gtcagtttta tctgaaacct caaagctgtg
     7381 ctttgagcaa cctgcgacta gcttcctagt ttgctttttg attttcattg agtatcaatt
     7441 tgaatggaaa atggaaagtt atcatcttgt aatgagttaa gcaacattct tgcaatctat
     7501 tttactttat atcacaatta attagtcaaa tattgataaa tcaataaaaa gagaggggaa
     7561 gaaatgctag agattcaaga tttactgtat caactccgct tgtctgagca agcgagtacg
     7621 caattgtttg aaaaaaggct tgggattagt ttgacacggt atcagatttt actgtttttg
     7681 ctggagcatt ctccttgtaa ccaaatggcg attcaggagc gtttgaaaat tgatcaggct
     7741 gctttgacac ggcatttcaa gattttggaa acggaaggtt tggtggagcg tcatcgtaat
     7801 cctgaaaatc agcgggaagt gttggtagag gctgcgaagt atgccaagga gcagttagtg
     7861 gtgaatcccc ctctgcaaca tatcaaggtt aaggaagaga tggaaagtat cttaacagag
     7921 tttgagagaa cagaactcag ccgtttatta aataaattgg ttttgggtat tgaaaatata
     7981 gaaatttaag gagaaataga tgtcaattat tacaattatt ttaacaacga tcgttgcttt
     8041 ggagcatttt tacatttttt atttggaaag tattgccacg caatcagatg cgactagtcg
     8101 tgtatttaat atggaaaagg aagaattggc tcatccgtca gtaagttcat tgttcaaaaa
     8161 tcaagggatt tataagactc tgctaggagt ctttctcttg tatgtcattt atttctcaca
     8221 gaatttagaa attgtgacta tttttgtctt atttgtgatt ggtgctgcga cttacggctc
     8281 tttaacagcg gataaaaaat tattttgaag caaggtagat cagctatttt ggccttgatt
     8341 agtattttac tctttaaata cacttgaagg ttgattctaa tctcgctaat cctttttaat
     8401 ccagaataag ggaaatatgt tatacttgtt tttaagaaaa aagtctcatt gaattggttt
     8461 tgaggagtta gaaatgaaag tattagtgac aggttttgag cccttttgag gccattaaag
     8521 gtttaccagc tgaaatccat ggtgctgagg tccgttagct agaggtgccg acagtttttc
     8581 acaaatctgc tcaagtattg gaagaagaga tgaatcgtta tcaacctgac tttgtccttt
     8641 gtattgggca agctggtgga agaactagtt tgacacctga acgagtggcc attaatcaag
     8701 acgatgcacg catttctgat aacgaagata atcaaccgat tgaccgtccc attcgcccag
     8761 atggtgcttc ggcctacttt agtagtttgc cgattaaagc gatggttcaa gctataaaaa
     8821 agagggctta ccggcctctg tttccaatac ggcagggact tttgtctgca gccatttgat
     8881 gtatcaggct ctctatttgg tagaaaagaa atttccatat gttaaggcag gttttatgca
     8941 tattccttat atgatggaac aggtggtgaa cagacagact attccagcta tgagtttagt
     9001 ggatattcgg cgagggatag aagcagcaat cggcgctatg atagaacatg gagatcagga
     9061 actcaagttg gtaggcggag aaactcattg atagaaaaaa gcttgagtgg aaaaaccttc
     9121 aagcttttgg acgttttcga gccaatactg ctcggtaaaa cataatttta gtgcattgga
     9181 tataaggtag gagtgaaaaa ctagcaatgc caaaggtaat ccaattgagg aagtaccaag
     9241 gaagaagctg taaatctagg acaaagcgct ggaacttgta gcccttcata aaggaacggc
     9301 tagtttttag gattcgtctt ggtgggacct gtcctaggtc tagactataa cagagaagaa
     9361 attccacctg tgaataggca taatactgtg gaatatagag gatatttcct acaatgatca
     9421 agatgagact tgcaagaaag tagagtccaa agaccatgag gaaacgctcg gtttcaactg
     9481 atgagagatc tagatttgga aactcaggat gtagggtgac gaattttttg gctaaaaagc
     9541 tactataaaa gaggaggtaa atcccaagta aattagggat actccataaa aagagataga
     9601 aacgtttgag aagtagggtc aaaaaggttt gagaaaatcg ctcctcatca aagagagcta
     9661 ggctgttttt tacagatggc tccgttttag aatctttcat gagtgtcagt gttgcataga
     9721 cggaactggt caaaagaata gtcccgataa aggagactag tagaggaaag aggtaggctt
     9781 gaagtatttg gccaagtatg ctgaaaaatg gctgttctaa aacagtcccg tggatccgag
     9841 ataagggatt aagaaaacta gataagatga ccagcatact gggaaggata tagaggagaa
     9901 agagacgggg ggtgtcagcc tgaaaatgtt ttgactcctg acgaattgtt tttaaatcaa
     9961 tttttggata gttcattctc ttattatacc atagttctta tacatagttc gtgacagttc
    10021 ctactttttt tgataaaatc atacagtgtg tccttgggca cactgtatga actgggactg
    10081 tctttcccag cttcggaggt aaaaaatgtc agattcacca atcaaatatc gtttgattaa
    10141 gaaagaaaaa cacacaggag ctcgtctggg agaaatcatc actccccacg gtacctttcc
    10201 gacacctatg tttatgccag ttgggacaca agccactgtc aaaactcagt cacctgaaga
    10261 attgaaggag atgggttcgg gaattatcct atcaaacacc tatcatctct ggcttcgccc
    10321 tggagatgaa ctcattgcac gcgctggtgg tctccacaag ttcatgaatt gggaccagcc
    10381 tatcttgaca gatagtggtg gttttcaggt ttattcttta gcagatagcc gtaatatcac
    10441 agaagaagga gtaaccttta aaaatcatct aaatggttct aagatgttcc tatccccaga
    10501 aaaagccatc tctattcaga ataatctggg ttcagacatc atgatgtcct ttgatgaatg
    10561 tcctcagttt tatcaacctt atgactacgt taagaaatcg atcgagcgta ccagccgttg
    10621 ggctgagcgt ggtttgaagg ctcaccgtcg tccacatgac caaggtttgt ttggaattgt
    10681 gcaaggtgca ggatttgaag accttcgccg ccaatcagct catgatcttg tcagcatgga
    10741 tttctcaggc tactctatcg gtggtttggc agtgggagaa acccatgaag agatgaatgc
    10801 ggtcttggac tttacaactc aactgctacc tgaaaataaa cctcgttatc tgatgggtgt
    10861 gggagcgcca gatagcttga tcgatggggt cattcgtggg gtggatatgt ttgactgtgt
    10921 cttaccgact cgaattgctc gtaacgggac ttgtatgacc agtcaaggac gtttggttgt
    10981 gaaaaatgcc cagtttgctg aggactttac gccactggat cctgagtgtg attgctacac
    11041 atgtaataac tatacacgcg cttaccttcg tcacctgctc aaggctgatg aaacctttgg
    11101 tatccgcttg actagctacc acaatcttta cttcttgctt aacttgatga agcaagtgcg
    11161 acaagccatc atggatgaca atctcttgga attccgtgag tattttgtgg aaaaatatgg
    11221 ctataataag tcaggacgta atttctaaaa tggaattgat ataagctaaa aatcctaagt
    11281 tttctcttag gatttttctt ctttttttga tagaataaag tgtacaatga aaggaagaat
    11341 aaactcgtat gcgcattaaa tggttttcct tggttaggat tacaggttta cttttggtac
    11401 tcttgtatca cttctttcag acgatctttc ctggaggatt tttcggggta gatgtctttt
    11461 tcacattttc aggtttcctg attacagctc tactcattga agaattttct aaaaaccatg
    11521 agattgattt gataggattt tttagaagac gcttttatcg gattgtgcca cctgtggttt
    11581 tgatggtctt ggtgaccatg ccttttactt tcttggttcg ccaagactat gttgctggaa
    11641 ttggtggcca gattgcgagc gtcttaggct ttatgaccaa cttctatgaa ctcctaacag
    11701 gtgggagtta tgaatctcag ttcattcctc atttgtttgt tcataattgg agtttggcag
    11761 ttgaggttca ctactatatt ctttggggat tggcagtttg gttcttatcc aaacaagcta
    11821 aatcaaatgg tcagttgaag gggatggtct ttctcttatc tgctgttgcc ttcttgatca
    11881 gtttcttctc catgtttatt ggtagttttc tagtgacctc ttattcctct gtttatttct
    11941 ccagtttaac tcatgtctat ccattctttt tgggaagtat gttagcaact attgtaggtg
    12001 ttcgtcagac gacttccctc gtcaagcagt tggataaaat ctgggattta cgaaagactt
    12061 tggtagtttt tggaggaggc tttggtttcc tagttctttt gactttcttt gtcaaattca
    12121 cttatctttt tgcctatctt atcggcttct tgcttgccag tcttgcagct cttgccatga
    12181 ttctggcggc gcgtgtctta catgaaaaga cacatcatat acaggagccg aagattatca
    12241 gctttttagc ggatactagc tatgcggttt atcttttcca ttggcctttc tatatcattt
    12301 tctcacagtt gacatcaaat cttcttgctg tattactgac tctgatttgt tcttatggct
    12361 ttgccagtct gtcattctat gtattggaac cttggattgc aggcaagaac acacctattt
    12421 tacaaactct tcgtcccctg ccttatattc acgcaattct tgtagcaggt acaggaatct
    12481 tgaccatcat tgtctgcacg gtgaccttgt tggcaccaca agtgggagcg tttgagacag
    12541 acttgactgt caatggcttg aagcaagctg caacaaatat tggccagacc aaggtgatgg
    12601 cagaacgggc agatgcaaac agtttgggaa ttgctgatgg cactatgtta attggtgact
    12661 cagtggcttt aagggcaaat acagcactac agacagctct tcctggagca cagattaacg
    12721 cgcaggtcag cgtaacaacc aagaccgcaa atgaaatcat gctaaataat agccagaata
    12781 aatttttacc taagacggtg gtcattgcga ctggggtaaa taatcctgag aattacaagg
    12841 atgactggga cagtatcgtg aaaaatcttc ctaagggaca ccatatgatt ttggtgactc
    12901 cttatgaggg agataagaca aaagagacct atgccatcgt tgagaaggct gctgcctata
    12961 tgagagaatt ggcagagaag acaccttaca ttacgatagc agattggaat caagttgcga
    13021 aagagcatcc agaaatttgg gcaggaacag accaggttca tttcgggagt gagagtagca
    13081 ctatcgaagc aggagcaaaa ttgtatgcag atacgattgc cacagctttg cagacagctc
    13141 aagacaagcc ggttaaatca aaataacttg tattaaaaaa gagaagagtt ggagaaatcc
    13201 agctctttta aaatatctcc aaaaaatagg tctataccat ttacaaataa aaaagaaagg
    13261 tttataatgt aattgacata ataaattgta gaatcaatct tttaaggagg ttaacattat
    13321 gcctaactat attaaagcgg atcagttttt ctacccacac ggagttcgtc gaggtggtta
    13381 cttggaactt gtggacggca agtttgggaa acatgtagag cagattcctg aaggggctga
    13441 ggtgattgac tatacaggtt atagcattgc cccaggtctt gtggatactc atattcatgg
    13501 atatgcaggt gtagatgtga tggacaacaa cattgaaggt acattgcata ctatgagtga
    13561 aggacttctt agtaccggtg ttaccagttt cttacccaca actttaacag ccacttatga
    13621 gcaattgctt gcagtcactg aaaatcttgg aaaccattat aaagaagcaa caggtgctaa
    13681 gattcgtggg atttattatg aaggtccata tttcacagaa acttttaagg gggcacaaaa
    13741 tccaacttat atgagagacc cgggtgttga ggagtttcat tcttggcaaa aagcggcaaa
    13801 tggcttgctt aataaaattg cccttgcacc agaacgtgat ggggtggaag actttgttcg
    13861 tacagttacg ggcgaaggtg tgacggttgc tcttggacat tcaaacgcga cttttgatga
    13921 agccaaaaaa gcagtcgatg ctggagcgag tgtttgggtg catgcctaca atggaatgcg
    13981 tgggttgact caccgtgaat tgggtatggt tggagccatg taccaattgc cacataccta
    14041 tgcagagttg atctgtgatg gtcaccacgt agatccaaag gcttgcgaaa ttcttatcaa
    14101 acaaaaagga acagaaaaca tcgctcttat cacagactgt atgacagctg ggggattgga
    14161 agacggagat tatatgttgg gagaattccc agttgtcgtt gcaaatggaa ctgcacgcct
    14221 caaatcgaca ggtaacttgg caggttctat cctcaaactc aaagatggtt tgaagaatgt
    14281 ggtcgaatgg ggaattgcga atccgcatga agcagtcatg atggccagct tcaacccagc
    14341 taaatccgtt cacatcgatg acgtctgtgg ccaaatccgt gaaggctacg acgctgactt
    14401 catcgtatta gataaagatt tggaattggt agcaacctac ctagatggcg taaaacgtta
    14461 tcaagcataa gagagaaagc agaagttaga gactaacttc tgctttttta tgcagggtac
    14521 tttactggta aataaaaagt taaaaaaatc acaaaaaaag cttgaagaaa caaagaaaaa
    14581 ggcttacaat tgaactataa atattacaaa taaaaaaacg gaggagtgct ttatgaaagc
    14641 ctatacttat gttaaaccag gacttgcttc ttttgttgat gtagacaaac cagttattcg
    14701 caagccaaca gatgctattg tgcgtattgt aaaaaccact atttgtggaa cagacctcca
    14761 tattatcaaa ggggatgttc ctacttgcca aagtggtacc attcttggcc acgaagggat
    14821 tgggattgtt gaagaagttg gggaaggagt ttctaacttc aaaaaaggtg acaaggtctt
    14881 gatttcttgc gtctgtgcct gtggtaaatg ctactactgt aaaaaaggaa tttatgctca
    14941 ctgtgaagac gaagggggct ggatttttgg gcatttgatt aatggtatgc aggctgaata
    15001 cctacgtgta cctcatgcag ataatactct ttaccatacg ccagcagact tgtcagacga
    15061 agctttggtt atgctatcag acattctgcc tactggatat gaaattggtg tcttaaaagg
    15121 gaaagtagaa cctggttgca gcgtagccat tattggttca ggtccagttg gattggctgc
    15181 tcttttaaca gcccaattct attcaccagc taaattgatt atggtagacc tagacgataa
    15241 ccgcttggaa actgcagtat cctttggtgc tactcataag gtaaactctt cagaccctga
    15301 aaaagccatt aaagaaattt atgatttgac agatggtcgt ggtgtggatg tcgctatcga
    15361 agctgttggt attcctgcaa catttgattt ctgtcaaaag attatcggtg tagacggaac
    15421 ggttgccaac tgtggtgtgc atggtaaacc agttgaattc gatttagata aactttggat
    15481 tcgcaacatc aatgtaacaa ctggtttggt atctacaaat acgactccac aattgttgaa
    15541 agcacttgaa agtcataaga ttgaaccaga aaaattggta actcactatt tcaaacttag
    15601 tgaaattgaa aaagcctacg aagtcttcag taaggcagca gaccaccatg ccattaaggt
    15661 cattatcgaa aacgatatct cagaagccta agtagtaaaa atatttttgt acataagcaa
    15721 atagaaattc agtcatccat cagatggctg gattttttat caaaaaatta agaaatgagc
    15781 atatttcttt ccttgtctgg cggaattggt tataatatac ggtacaaagg aatgaatgaa
    15841 tatgtatcgt gttatagaaa tgtacggaga ttttgaaccg tggtggttct tagaaggttg
    15901 ggaagaagat attgtagcaa gtagaaaatt tgaccagtat tatgatgctc tcaaatacta
    15961 caaaacttgc tggtttagat tggaacaaga atcgcctctt tataaaagta gaagcgactt
    16021 gatgaccatt ttttgggacc cggaagacca acgctggtgt gatgaatgtg atgagtattt
    16081 acaacaatac cattctttgg ctcttttgca ggatgagcag gttatcccag acgaaaaact
    16141 acgctcaggc tatgaaaaac aaaccagtca ggaaaggaat cgttcttgcc gtatgaaatt
    16201 aaaatagaga aaagtaactt ttttggagtt gcttttttta tttttctaac tctttgcgaa
    16261 tagtataggt gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcagc
    16321 tcggaaaaaa gggacgcagg atatctattt tgtccctaag ttagacgcct atgagcttca
    16381 tatgagggta ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc
    16441 cgttatcagt cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca
    16501 actgggttcc tgtgattatg cctatgacca gaagatagcg tctctacgtt tatctactgt
    16561 aggcgattat cgggggcatg agagtttggt tatccgtttg ttgcacgatg aggagcagga
    16621 cctgcatttt tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact
    16681 ctatcttttt gctggtccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa
    16741 gtcactcttt aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga
    16801 cgacatgctt cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa
    16861 actttccttg cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac
    16921 ggcgcgtgca gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc
    16981 caagagtatc cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt
    17041 ggcagttgtt ttgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga
    17101 ctttgcaaac agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca
    17161 gcttcttaaa gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag
    17221 ctaagcaaaa aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg
    17281 tggagactat ctctttttta gataggagtg ctttgttgga caagcagtgt gtgacccaga
    17341 tgcgtgtggg cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt
    17401 caagtgctat tgtcactcag ttatccctag ctgaagttca tggcaatctc cacctgagtt
    17461 tgggaaagat agaagaatat ctggacaatc tggccaaggt caagaaaaaa ttgattgaag
    17521 tagcgaccta tcccttgatt ttgctgggtt ttcttctctt aattatgctg gggctacgga
    17581 attacctgct cccacaactg gatagtagca atattgccac ccaaattatc ggtaatctgc
    17641 cacaaatctt tctaggaatg atagtttttg tttcagtagg tgtcctttta gcactcactt
    17701 tttataaaag aagttctaag atgcgcgtct tttctatctt agcgcgcctt ccttttattg
    17761 gaatctttgt gcagacctat ttgacagcct attatgcacg tgaatggggg aatatgattt
    17821 cacagggaat ggagttgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct
    17881 ttaaagaaat cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga
    17941 cgataggaac ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag
    18001 ttaagtccaa gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt
    18061 ttacccgagt caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac
    18121 tgattatcgt tttactttat gcggcaatgc tcatgcctat gtatcaaaat atggaggtaa
    18181 atttttaaaa tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca
    18241 ttggtggaaa tgttggtggt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct
    18301 aatctgacca agcaaaaaga agcagtcaat gacaaaggaa aagcagctgt tgttaaggtg
    18361 gtggaaagcc aggcagaact ttatagctta gaaaagaatg aagatgctag cctaagaaag
    18421 ttacaagcag atggacgcat cacggaagaa caggctaaag cttataaaga ataccatgat
    18481 aaaaatggag gagcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct
    18541 cttggttttg ggtcttgtga gtatccttgc cttgggcttg tccggctctg ttcagtccac
    18601 ttttgcggcg gtagaggaac agattttctt tatggagttt gaagaactct atcgggaaac
    18661 ccaaaaacgc agtgtagcca gtcagcaaaa gactaatcta aatttagatg ggcagacgct
    18721 tagcaatggc agtcaaaagt tgacagttcc taaaggaatt caggcaccat caggccaaag
    18781 tattacattt gaccgagctg ggggcaattc gtccctggct aaggttgaat ttcagaccag
    18841 taaaggagcg attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga
    18901 aacaaaaaat tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca
    18961 gcattgcgac cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct
    19021 tgcaaaagga agaagtcttg agggtagcta agatggccct gcagacgggg caaaatcagg
    19081 taagcatcaa cggagttgag attcaggtat tttctagtga aaaaggattg gaggtctacc
    19141 atggttcaga acagttgttg gcaatcaaag agccataagg tcaaggcttt taccttgtta
    19201 gaatccctac ttgccctcat tgtcatcagt gggggattac tcctttttca aactatgagt
    19261 cagctcctca tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg
    19321 tttgtggacc aacttgaggc agaattagac cgttcgcagt tcgaaaaagt agaaggcaat
    19381 cgcctataca tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat
    19441 tttcgtaaaa cgaatgctcg tggtcgaggt tatcagccta tggtttatgg cctcaaatca
    19501 gctcagatta cagaggacaa tcaactggtt cattttcgtt tccagtttca aaaaggctta
    19561 gaaagggagt tcatctatcg tgtggaaaaa gaaaaaagtt aaggcaggtg ttctcctcta
    19621 cgcagtcacc atagcagcca tctttagtct tttgttgcaa ttttatttga accgacaagt
    19681 cgcccactat caagactatg ctttgaataa agaaaaattg gttgcttttg ctatggctaa
    19741 acgaaccaaa gataaggttg agcaagaaag tggggaacag gtttttaatc taggtcaggt
    19801 aagctatcaa aacaagaaaa ctggcttagt gacgagggtt cgtacggata agagccaata
    19861 tgagtttctg tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt
    19921 agcgaccgat tcaagcgaaa aagtggagaa gaaaaaatca gaagagaagc ctgaaaagaa
    19981 agagaattcc tagtcaattc aactataatg cgttgaatcc agaatagtcc actgtagttt
    20041 ctagaaaatt gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag
    20101 tttactatac tttgtgctaa attaaagata tgaaacatga ttttaaccac aaagcagaaa
    20161 ctttcgattt ccctaaaaat atcttcctcg caaacttggt atgtcaagca gccgagaaac
    20221 agattgatct tctatcatac aaagaaattt tagatttcgg tggtggcacg ggtctattag
    20281 ccttgcccct aacccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag
    20341 aaaatgttgg agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt
    20401 ttggagcaag atttaccgaa aaatcccttg gagaaagagt ttgattgcct tgctgttagt
    20461 cgggttcttc atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg
    20521 aaggaagatg ggaaactcat cattgctgat tttaccaaga cagaagctaa tcatcatgga
    20581 tttgatttag ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt
    20641 cagattctct atagcgctga agacctgttt caaggaaatc actcagaatt ctttttaata
    20701 gtagcccaaa aatcactcgc ctagtcaggg agtgattttt ctataagaat ggaaaaaaga
    20761 agggaaattt gataagatag gaatatggat tttgaaaaaa ttgaacaagc ttatacctat
    20821 ttactagaga atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg
    20881 gtggagcaaa acagcatcta tctggatggt gagactgagc tagaacaggt caaagacaac
    20941 aatcagaccc ttaagcgttt agcactacgc aaagaagaat ggctcaagac ctaccagttt
    21001 ctcttgatga aggctgggca aacagaaccc ttgcaggcca atcaccagtt tacaccggat
    21061 gctattgctt tacttttggt gtttattgtg gaagagctgt ttaaagagga ggaaattact
    21121 atcctcgaaa tgggttctgg gatgggaatt ttgggcgcta ctttcttgac ctcgcttact
    21181 aaaaaggtgg attatttggg aatggaagtg gatgatttgc tgattgattt ggcagctagc
    21241 atggcagatg taattggttt gcaggctggc tttgtccaag gagatgccgt tcgtccacaa
    21301 atgctcaaag aaagtgatgt ggtcatcagc gacttgcctg ttggctatta tcctgatgat
    21361 gccgttgcgt cgcgccatca agttgcttct agtcaagaac atacttacac ccatcacttg
    21421 ctcatggaac aaggacttaa gtacctcaag tcagacggat acgctatttt tctagctccg
    21481 agtgatttgt tgaccagtcc tcaaagtaat ttgttgaaag tctggttgaa agaggaggca
    21541 agtctggttg ctatgattag tttacctgaa aatctctttg ctaatgctaa acaatctaag
    21601 actattttta tcctacagaa gaaaagtgaa atagcagtag agccttttgt ttatccactt
    21661 gctagcttgc aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact
    21721 caaggtactg aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt
    21781 atcatgttat gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat
    21841 tatacttaat gccagaagaa aaagtattgg cgaaaggttt gattgaacgt atcggtttga
    21901 aagattcaat ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatattg
    21961 aaaatcatac acaagctgtt aaaattttat tggatgactt gattcgtttc gatattatca
    22021 aggcttatga cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca
    22081 aagaatcaac agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg
    22141 ctcctctaca caacccggca aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag
    22201 acattaccag tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt
    22261 atcgctaccc tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc
    22321 atggtacaag tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag
    22381 aagacttgaa gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag
    22441 ccggcaaatc tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa
    22501 cgcgtacagg ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt
    22561 ttaacacacc agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt
    22621 ctgctaattc tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg
    22681 ctagcttggc ttatgaaatg tatgttgacc gtatccaaaa acatatcggt cagtaccttg
    22741 cagtgctaaa tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga
    22801 gtttccgtcg tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa
    22861 agaatgtctt tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg
    22921 ttattccaac agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag
    22981 tgaaactaaa aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt
    23041 ctgatgaaat tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag
    23101 tagtaattta atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa
    23161 gattttaagg cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac
    23221 caattagaaa accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg
    23281 aatgccgtca ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa
    23341 gggagtctgg tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg
    23401 ggatacgcag agatggagaa aaatctactc cacgtattaa aattatcaaa gatttaccgg
    23461 gaaggaaatg ggagtgaaaa agaaactaaa gttgactagt ttgctaggac tgtctctgtt
    23521 aatcatgaca gcctgtgcga ctaatggggt aactagcgat attacagccg aatcggctga
    23581 tttttggagt aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat
    23641 tagtatcgga gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt
    23701 ctttcaggtg caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc
    23761 gcttcgagaa caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat
    23821 gcgtaaagta tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat
    23881 tcagatgccg gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac
    23941 aggtcatttc ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt
    24001 agcagcagta ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa
    24061 tggcgctacg actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta
    24121 tgcgccaggt ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac
    24181 ctatttcttg aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca
    24241 aaaagatttg gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat
    24301 aaggaggaat ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa
    24361 aggattgaaa gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga
    24421 gaaaaaaggc tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat
    24481 tagtgaaacg actgttgtca aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat
    24541 caatgatttg aacgagcctg tgaagacggt tagtgaagaa accgttgacc ttggtcatgt
    24601 ggttgatgct attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc
    24661 tgaaatctta aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga
    24721 gattttaaat gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct
    24781 tgaaactgag caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga
    24841 gcaaagttat gatattgccc aggtggctac ggatgtgact gcctatgttc aagcgattgt
    24901 ggatgacatg gatgttgaag ctacactttc aaatgattat aaccgtcgta gcatcaatct
    24961 acaaattgac accaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc
    25021 cttgcaactg ttggctcaaa attatcttta caaccgctat tccagaacct tctacgttac
    25081 aatcaatgtc aatgattatg tcgaacaccg tgcagaagtc ttgcagacct atgcgcaaaa
    25141 attggcgact cgtgttttgg aagaagggcg cagtcatcaa acagatccaa tgtcaaatag
    25201 cgaacgcaag attatccatc gtattatttc acgtatggat ggcgtgacta gttactctga
    25261 aggtgatgag ccaaatcgct atgttgttgt agatacagaa taagtaaaat cagggttgac
    25321 ctgatttttt gctagttaga ggaggttaaa ctgatgttga ataagataag agactattta
    25381 gactttgctg gtttgcagta ccgtaatcct gataaagcgg gagcagagcg agagaagatg
    25441 ctggcattcc gccacaaagg acaagaggcc cgaaaggctt ttacagaact ggccaaagcc
    25501 tttcaagcaa gccatccaga atggcaactc caacagacta gccagtggat gaatcaggcc
    25561 cagcgtttga gaccacattt ttgggtttat ctacagagag acggacaagt gacagaacct
    25621 atgatggcct tacgtttgta tgggacatct actgactttg gaatttcttt ggaagtcagt
    25681 ttcatcgaac gtaagaagga tgagcaaaca ctgggcaagc aggccaaagt tttagacatt
    25741 ccaaccgtta aagggattta ttatctaacc tactctaatg gtcaaagtca acggtgggag
    25801 gcgaatgaag aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa
    25861 gttttagtga aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa
    25921 ggcttattga agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat
    25981 aatttgtaaa acatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt
    26041 ggtctttttg tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag
    26101 aacaattatg gaagtcgttt caagtgttct aaattggttt tctagcaata ttttgcagaa
    26161 tcccgcattt ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc
    26221 ccatgacgtt ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg
    26281 tgctggtggt ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca
    26341 aattggtgca gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc
    26401 agcagagttt ccagattttg ttggaactgc aactacagct ctattgattg gttttggaat
    26461 aaatatcttg ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg
    26521 tcacatcatg gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca
    26581 attgcgcaat gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt
    26641 tagttcaaat atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat
    26701 tggtcaccaa cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa
    26761 gaaagaagaa agtttagaca atcttaaatt acctaagttc ctctcaatct tccacgatac
    26821 agttgttgca tctgctacct tgatgctcgt attcttcgga gccattcttt taatcttggg
    26881 tccagacatt atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa
    26941 acaagatttc tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt
    27001 tttgatgcaa ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc
    27061 aaacaaattg ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg
    27121 ttctccaaat gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat
    27181 tgttttgctc atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt
    27241 ctttgacaat gcagccattg cggtctacgc tgataaacgc ggtggatgga aagcggctgt
    27301 tatcctttcc tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct
    27361 tctcgatttg gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct
    27421 tggatttgga tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt
    27481 cttgcttgtt attcctcaac ttcaatttgc caaagcaaaa gataaagaga aatattacaa
    27541 cggtgaagtt caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat
    27601 tagcagcgtg cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg
    27661 ctctccgtaa gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta
    27721 aaggtttagc agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg
    27781 aagggcgaac taatgggaag ttaattgggc ttgataactt gatggatgat aaagaaatca
    27841 ccgaaaaact cagtcaagca ctacagtaaa aggttggagg gggctggaca gaaactgaga
    27901 gttatcgttt ctgtccttct ccctctttaa ataaaggagg cagatatgaa tttaaaacaa
    27961 gctttaattg acaatgactc gatccgacta ggtttagagg ctaacaattg gaaagaagca
    28021 gtcaaggtag cagtagatcc cttgattgaa agtggggcaa ttttgccaga gtattacgat
    28081 gctatcattg aatcgactga agagtatggg ccttactata tcttgatgcc aggtatggct
    28141 atgccccacg ctagacctga agctggtgtg caaagtgatg ccttttcatt gattacctta
    28201 caaaatcctg ttgtattttc agatgggaaa gaggtatctg ttttgttggc actagcagca
    28261 acaagctcaa aaattcacac aagtgtagcc attccacaaa ttattgccct gtttgaatta
    28321 gacgattcta ttgcacgttt acaggcttgc cagactaaag aagatgtctt ggctatgatt
    28381 gaagaatcta aggatagccc ttatctcgaa ggattggact tggaaagtta gaaagaggaa
    28441 taaagaaatg acaaaaagaa tacctaattt acaagttgca ttagaccatt cagacttgca
    28501 aggagcgatt aaagcagctg tttctgttgg tcaggaagta gatattatcg aagctggaac
    28561 tgtttgcttg cttcaagttg gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga
    28621 taagattatt gtggcagaca caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa
    28681 tgcggttcgt ggagcagact ggatgacttg tatctgttgt gcaaccatcc ctactatgga
    28741 agcagctcta aaggctatca agactgaacg aggagaacga ggcgaaatcc agatcgagct
    28801 ttatggcgat tggacttttg aacaagctca gctttggcta gatgcaggta tctcacaagc
    28861 tatttatcac caatctcgtg atgctcttct tgctggtgaa acttggggtg aaaaagacct
    28921 taataaggtt aaaaaactca ttgacatggg cttccgtgta tctgtaacag gtggtctaga
    28981 tgtagatact ctcaaactct ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg
    29041 aattacagag gctgcggatc cagcaggaac agcgcgtgcc ttcaaggatg aaatcaaacg
    29101 aatttggggg taaatcatgg tacgtccaat tggaatttat gaaaaggcaa ccccaacaca
    29161 ctttacttgg ctagaacgtt taaattttgc caaggagtta ggctttgatt ttgtcgagat
    29221 gtctattgac gaacgtgacg agcgtttagc aagacttgac tggagtaagg aagaacgctt
    29281 ggaagttgtc aaagcaatct atgaaactgg tgttcgtatt ccttctatct gtttttcagg
    29341 ccatcgtcgc tacccattgg gttcaaaaga tccagttcta gaggaaaaat ctctagaact
    29401 catgaaaaaa tgtatcgaat tagctcaaga cttgggagtt cgtacgattc aattagctgg
    29461 ttacgatgtt tactatgagg aaaagtcacc ccagacacgc caacgtttta tcaaaaattt
    29521 gagaaaagcc tgtgactggg ctgaagaagc tcaggtggta cttgctattg aaattatgga
    29581 tgatcctttc atcaatagca tcgaaaaata tttggctata gaaaaagaga ttgactctcc
    29641 tttcctcttt gtatatccag atattggtaa tgtgtctgca tggcataatg atatctatag
    29701 tgagttttat cttggtcatc atgccatcgc agctctccat ctcaaggata cttatgcagt
    29761 gacagaaagt tcaaagggcc agttccgaga tgtacctttt gggcaaggtt gtgtcaaatg
    29821 ggaagaagtt ttcgatattt taaaggaaac caattataat ggacctttcc taatcgaaat
    29881 gtggtctgaa aattgtgaaa tagtagaaga aacacgcgca gccattcaag aggcgcaagc
    29941 ttttctctat ccactcatta agaaagcagg tttgatgtaa gatgaatcaa gtaatcaatg
    30001 ctatgcgtaa acgagtctgt gatgccaatc aatcattgcc aaaacatgga cttgtcaaat
    30061 ttacctgggg gaatgtatct gaagtcaatc gcgaactcgg tgtcattgtt atcaaaccat
    30121 caggcgtgga ttatgacgaa ttgacacctg aaaacatggt agtgactgat ctagatggta
    30181 agatcctaga aggggattta agaccatctt ccgacctccc aactcatgtg caattatata
    30241 aggcttggtc agaaattggt agtgtggttc acacccattc gacagaagct gttggttggg
    30301 ctcaggcagg tcgtgatatt cctttctacg gaacaaccca tgcagattat ttctacggtt
    30361 caatcccttg cgcccgtagt ttgaccaagg acgaagtaga agtggcctat gaaaaagata
    30421 ctggcctggt tatcgtagaa gagtttgaac atcgcggact taacccggtt gaagtaccag
    30481 gaattgttgt acgcaatcac ggtccattca cctggggcaa aaatccagag aatgctgttt
    30541 atcactctgt cgtactagag gaagtatcaa agatgaatca ctttacagaa caaatcaatc
    30601 caagagttga acctgctccc cagtacatac tagaaaaaca ctaccaacgt aaacatggac
    30661 caaatgctta ttatggtcaa aagtaagaac gatgaaggag gagaaaaaga taaatttagc
    30721 tcctcttttt acatttgatt tttattgaga gtaaagttgg agttgaagta attttaaaag
    30781 attttttaga aatagcgctt gatatatata tggtaaaata aaaagaattg ctgtgatatc
    30841 aatagatttg ggggattttt taatatggta ctggataagg caagttgtga tttgcttcaa
    30901 tatttgatgg atcaagaaac gtccaaaacg attatggcga tttcgaaaga tttgaaagag
    30961 tcaagaagga aaatttatta tcacattgac aaaatcaatg ctgctctggg tgacgaggcg
    31021 cttcacatca ttagtattcc acgaattggt attcacttaa cggaagagca gagagatgct
    31081 tgttgtaaac tattatcgga agtagattcg tacgattata tcatgagtgc gcatgaacgt
    31141 atgatgataa tgttactatg gataggtatt tctaaagaac gtattacgat tgaaaaattg
    31201 atagagttaa cagaggtatc taggaatact gttctcaatg atttgaatag tattcgttat
    31261 caactaactt tggaacaata tcaggtgacc ttgcaagtga gcaagtcaca gggataccac
    31321 cttcatgccc accctcttaa taaaattcag tatcttcaat cgcttctata tcatattttt
    31381 atggaagaaa atgccacttt tgtatctatt ttagaagata agatgaaaga gaggttagat
    31441 gatgagtgtt tgctttctgt tgaaatgaac caatttttta aggaacaggt tcctttagtt
    31501 gaacaagatt tagggaagaa aataaaccat catgaaataa cttttatgtt gcaggttcta
    31561 ccttatttgc tgttaagctg tcataatgtt gaacagtatc aagaaagaca tcaggatata
    31621 gagaaagaat tttctttgat aagaaaaaga atagagtatc aggtgtctaa gaaattagga
    31681 gaacggttgt ttcaaaagtt tgaaatttct ttgtcaggac ttgaagtttc tcttgtagct
    31741 gttctcctcc tctcctatcg taaagatttg gatattcatg cagaaagtga tgattttcgg
    31801 caattaaaac ttgctttaga agaatttatc tggtattttg aatcacaaat ccgaatggag
    31861 attgagaaca aggatgattt gttacgaaat ttgatgatcc actgtaaagc cttgttattt
    31921 agaaagactt acggtatttt ttctaaaaat cctctaacaa aacaaattcg atccaagtat
    31981 ggagaattat ttttagtcac tagaaaatct gcggaaattt tagaaggagc atggtttatt
    32041 cggctaacag acgatgatat tgcctatttg acgattcata ttggaggatt tttaaagtat
    32101 acaccatcgt ctcaaaaaaa tatgaaaaaa gtttatctcg tttgtgatga aggtgttgcg
    32161 gtttcgagac ttttgctgaa acaatgcaaa ctttattttc caaatgagca aattgacact
    32221 gtatttacaa cagaacaatt taagagtgtg gaagatattg cacaagttga tgtagtgatt
    32281 actactaatg atgatttgga tagcagattt ccgattttaa gggttaatcc tatccttgaa
    32341 gcagaagata ttttgaaaat gctagactat cttaaacaca atatatttcg taatgagagc
    32401 aaaagtttca gtgaaaatct ttctagtctt atttcgtctt atattgtaga cagcaagttg
    32461 gctagtaagt tccaagaaga ggttcaaaca cttataaatc aagaaatagt agttcaagct
    32521 tttttggaag atatttgaag gacagtccaa tgatgaacac aaacctgtgt ttttcttggt
    32581 cttttttagt gttttgaagg gtggtatact aatctcaaag ataacaatta tatccaaagg
    32641 aggcaacata tgccaaacgt caaagaaatt acaagagagt catggatttt agccactttc
    32701 ccagagtggg gaacatggtt gaacgaagaa atcgaagaag aagtcgtacc tgaaggcaac
    32761 tttgccatgt ggtggctagg caactgtggt acttggatta agacaccagc tggtgctaac
    32821 gttgtcatgg acctttggtc aaaccgtgga aaatcaacca aaaaagtgaa agatatggtt
    32881 cgtgggcacc aaatggcaaa tatggcaggt gttcgtaagt tgcaaccaaa cttgcgtgtt
    32941 cagccaatgg ttatcgatcc atttgctatc aacgaactag actattactt agtttcacac
    33001 ttccacagtg atcatatcga cccatacaca gctgcagcaa ttctcaacaa tcctaagtta
    33061 gagcatgtta agtttatcgg tccttaccac tgtggacgaa tctgggaagg atggggtgtt
    33121 ccaaaagaac gtatcatcgt tgttaaacca ggtgacacta tcgaattaaa agatatgaag
    33181 attcatgcag tagaatcatt tgaccgtact tgcttggtaa ctctcccagt gaacggtgct
    33241 gatgagacag gcggtgaact tgctggcttg gctgttacag atgaagaaat ggctcaaaag
    33301 gctgttaact atatctttga aacaccaggt ggaaccatct atcatggtgc agattctcac
    33361 ttctcaaact attttgcaaa acatggtaaa gactttaaaa ttgatgttgc tttgaataac
    33421 tatggtgaaa atccggtagg tatccaagac aaaatgacat ctatcgacct tcttcgtatg
    33481 gcagaaaatc tgcgtaccaa agtcattatc ccagttcact atgatatctg gtctaacttc
    33541 atggcttcta ctaatgagat tctagaactt tggaaaatgc gaaaagatcg cttgcaatac
    33601 gatttccatc catttatctg ggaagttggc ggtaagtaca cttatcctca agatcaacac
    33661 ttagtagaat accatcatcc acgtggtttt gatgattgtt ttgaacaaga ctctaacatt
    33721 caatttaaag ctttgctata atataaaaat attctttgga ggttatccgt atgttgcatg
    33781 atacggataa ttttcatata atagtaaaat agaatgtgtg attcaataat cacctcaaat
    33841 agaaaggaaa ttctatgtca aatctatctg ttaatgcaat tcgttttcta ggtattgacg
    33901 ccattaataa agccaactca ggtcatccag gtgtggttat gggagcggct ccgatggctt
    33961 acagcctctt tacaaaacaa cttcatatca atccagctca accaaactgg attaaccgcg
    34021 accgctttat tctttcagca ggtcatggtt caatgctcct ttatgctctt cttcaccttt
    34081 ctggttttga agatgtcagc atggatgaga ttaagagttt ccgtcaatgg ggttcaaaaa
    34141 caccaggtca cccagaattt ggtcatacgg cagggattga tgctacgaca ggtcctctag
    34201 ggcaagggat ttcaactgct actggttttg cccaagcaga acgtttcttg gcagccaaat
    34261 ataaccgtga aggctacaat atctttgacc actatactta cgttatctgt ggagacggag
    34321 acttgatgga aggtgtctca agcgaggcag cttcatacgc aggtttgcaa aaacttgata
    34381 agttggttgt tctttatgat tcaaatgata tcaacttgga tggtgagaca aaggattcct
    34441 ttacagaaag tgttcgtgac cgttacaatg cctacggttg gcatactgcc ttggttgaaa
    34501 atggaacaga cttggaagcc atccatgctg ctatcgaaac agcaaaagct tcaggcaagc
    34561 catctttgat tgaagtgaag acggttattg gatacggttc tccaaacaaa caaggaacta
    34621 atgctgtaca cggcgcccct cttggagcag atgaaactgc atcaactcgt caagccctcg
    34681 gttgggacta cgaaccattt gaaattccag aacaagtata tgctgatttc aaagaacatg
    34741 ttgcagaccg tggcgcatca gcttatcaag cttggactaa attagttgca gattataaag
    34801 aagctcatcc agaactggct gcagaagtag aagccatcat cgacggacgt gatccagtcg
    34861 aagtgactcc agcagacttc ccagctttag aaaatggttt ttctcaagca actcgtaatt
    34921 caagtcaaga tgccttgaat gttgtggcag ctaaattacc aaccttccta ggtggatcag
    34981 ctgaccttgc tcactcaaac atgacttata tcaagacgga tggacttcaa gacgatacca
    35041 atcgcttgaa tcgtaacatt cagtttggtg ttcgtgaatt tgcaatggga acaatcttga
    35101 acgggatggc ccttcatggt ggacttcgtg tatacggtgg aactttcttc gtcttctctg
    35161 actatgtgaa ggcagctgtc cgcttgtcag ccttacaagg acttcctgtg acttatgtct
    35221 ttacccatga ttcaatcgca gttggggaag atggtccgac tcacgaacca gttgagcatt
    35281 tagcaggtct tcgtgctatg ccaaatctaa atgttttccg tccagcagat gcgcgtgaaa
    35341 cgcaagcagc ttggtacctt gcagtgacaa gtgagaaaac accaactgcc cttgtcttga
    35401 cacgtcaaaa cttgactgtt gaagatggaa cagacttcga caaggttgct aaaggtgctt
    35461 atgttgtata tgaaaatgca gccgactttg ataccatctt gattgcgaca ggttcagagg
    35521 ttaatcttgc tgtctcagct gctaaagaat tggctagtca aggcgaaaaa atccgcgtag
    35581 tcagcatgcc atctacagat gtctttgata aacaagatgc agcttacaag gaagagattc
    35641 ttccaaatgc agtccgccgt cgtgttgcag tcgaaatggg tgcaagtcaa aactggtaca
    35701 aatatgttgg tctcgatggt gccgttctag gtattgatac cttcggagcc tctgccccag
    35761 caccaaaagt attggcagaa tatggcttta ctgtagaaaa tcttgtaaaa gttgttcgaa
    35821 acttgaaata atcctaaaaa tcagggcgta agctctggtt tttcttacca gaaaagtaag
    35881 gtacaatctt gtaaaagtag ctgaaatttg atatagtagt cctatgtaaa agacaaagga
    35941 gaaaacaatg aatccaaata ttactttttt aatcatgctt gtaggtatga tggccttgat
    36001 gttctttatg caacgctctc aaaagaaaca agctcaaaag cgtatggaaa gcttaaataa
    36061 actacaaaaa ggctatgaag tgattacaat cggtggactt tatggaacag tcgatgaagt
    36121 agatacggag aagggaacaa tagttcttga cgtagatgga gtttacttga cttttgaact
    36181 agctgctatc aagacagtat taccgctgaa agaaacagct tcactagaag gcgcaattga
    36241 aaaataagac gggatcacga actcccgttt tctataaaag aaaggaaatg ggatgaaaaa
    36301 attagtcttt gtctgtctgg gaaatatttg ccgtagccct atggccgagt ttgttatgaa
    36361 atcaatgaca gataactacg aaatccaaag tcgagcaact tcctcttggg aacatggcaa
    36421 tccgattcat aaggggactc agggaatttt tcaagagtat gagattcctt atgacaagaa
    36481 caagacatcg cttcagatta gtaaggaaga ttttgaagcc tttgattata ttatcggaat
    36541 ggacgcttca aatatttctg acttacgtca gatgtgtcca gtagactgtc aagataagat
    36601 ttactcattt tcatctgaaa gtgttccaga cccttggtat acaggagatt ttgaagaaac
    36661 ctatcgacgt gttcaagagg gctgtcaagc ttggttagaa cgtttagaaa aggagagtta
    36721 aggtggaaaa tcttacgaat ttttacgaaa agtatcgtgt ctatctgact cgtccacgtt
    36781 tagagctttt ggcagtagtt accattgttt tctgtgctgt actcgtcttt tttctaaata
    36841 ttccaggaaa aggtgtctta aaactcgata atggaacgat tgtttatgat ggcagtcttg
    36901 tccgtggtaa aatgaatggt caaggtacca ttaccttcca aaatggagac caatatacag
    36961 gtggcttcaa caatggagcc ttcaacggaa aaggtacctt tcaatctaaa gaaggctgga
    37021 cctacgaagg tgattttgta aatggtcagg ctgaaggaaa agggaaacta acaacagaac
    37081 aagaagtcgt ttatgaagga acttttaaac aaggcgtttt tcaacaaaaa taaagcctcc
    37141 ttatcaaagg aggtattatt agaattacaa ggtaagcgct tacctgtaaa tccctttctt
    37201 tccaaatccc tcttccaagc aagtttgtga aataaaaaat atttgaaata aatttcacaa
    37261 acttcaaaga taaaacctga taagaaaaga aaatgagaaa agtttcacaa gagtttaaaa
    37321 attctttgtg aaatgtttat gaaactgttt acaaagttga aataatacgt tataataaac
    37381 ttgtgaaaaa attaacaaag gatatcgttc cttgaaagct atggaggaaa atatggctga
    37441 taaaaaaact gtgacaccag aggaaaagaa actcgttgct gaaaaacacg tagatgagtt
    37501 ggttcaaaaa gctctagttg cccttgaaga aatgcgtaaa ttggatcaag agcaagttga
    37561 ctacatcgtt gccaaagcat cagtagcagc tttggatgcc cacggagaat tggctttaca
    37621 tgcctttgaa gaaacaggac gtggtgtatt tgaagataaa gcaactaaga acttgtttgc
    37681 ctgtgaacac gtagtaaaca acatgcgtca cactaagaca gttggcgtta tcgaagaaga
    37741 cgatgtaaca ggattgactc ttattgctga accagttggt gttgtttgtg gtattactcc
    37801 aacaacaaac ccaacatcaa cagcaatctt caaatcattg atttcattga agacacgtaa
    37861 cccaatcgtc tttgccttcc atccatcagc acaagaatca tctgctcatg cagctcgtat
    37921 cgtccgcgat gcagctatcg cagctggtgc tcctgaaaac tgtgtgcaat ggattactca
    37981 accatctatg gaagcaacaa gtgcccttat gaaccacgaa ggtgttgcga caatccttgc
    38041 aacaggtggt aatgccatgg ttaaggcggc ttattcatgt ggtaaaccag ctcttggggt
    38101 aggtgccgga aacgttccag cttatgttga aaaatcagca aacattcgtc aagcagcaca
    38161 cgatatcgtc atgtctaaat catttgataa cggtatggtc tgtgcatctg aacaagcagt
    38221 tatcattgat aaagaaattt acgatgaatt tgtagcagag ttcaaatctt accacactta
    38281 ctttgtaaac aaaaaagaaa aagctcttct tgaagagttc tgcttcggcg tcaaagcaaa
    38341 cagcaaaaac tgtgctggtg caaaattgaa cgctgacatc gttggtaaac cagcaacttg
    38401 gattgcagaa caagcaggat ttacagttcc agaaggaaca aacattcttg ctgcagaatg
    38461 taaagaagtt ggcgaaaatg agccattgac tcgtgaaaaa ttgtcaccag ttattgccgt
    38521 tttgaaatct gaaagccgtg aagatggtat taccaaggct cgtcaaatgg ttgaatttaa
    38581 cggtcttgga cactcagcag ctatccacac agctgacgaa gaattgacta aagaatttgg
    38641 taaagctgtt aaagctattc gtgttatctg taactcacct tctacttttg gtggtatcgg
    38701 ggacgtttac aatgccttct tgccatcatt gacacttgga tgtggttctt acggacgcaa
    38761 ctcagttggg gataacgtta gtgccattaa cctcttgaat atcaaaaaag tcggaagacg
    38821 gagaaataac atgcaatgga tgaaacttcc ttcaaaaaca tactttgaac gtgattcaat
    38881 tcaatacctt caaaaatgtc gtgacgttga acgtgtcatg atcgttactg accatgccat
    38941 ggtagagctt ggtttccttg atcgtatcat cgaacaactg gaccttcgtc gcaataaggt
    39001 tgtttaccaa atctttgcgg atgtagaacc ggatccagat atcacaactg taaaccgtgg
    39061 tactgagatt atgcgtgcct tcagaccaga taccatcatc gcactcggtg gtgggtctcc
    39121 aatggatgct gccaaagtaa tgtggctttt ctacgagcaa ccagaagtgg acttccgtga
    39181 ccttgtccaa aaattcatgg atatccgtaa acgtgccttc aagttcccat tgcttggtaa
    39241 gaagactaaa ttcatcgcga ttccaactac atctggtaca ggatctgaag taacaccatt
    39301 tgccgttatc tctgataaag caaacaaccg taaataccca atcgctgact actcattgac
    39361 accaactgtg gcaattgtag accctgcttt ggtattgaca gttccaggat ttgttgctgc
    39421 tgatactggt atggacgtat tgactcacgc gacagaagca tacgtatcac aaatggctag
    39481 tgactacact gatggtttag cacttcaagc tattaaattg gtctttgaaa atctcgaaag
    39541 ctcagttaag aatgcagact tccactcacg tgagaaaatg cataacgctt caacaatcgc
    39601 tggtatggcc tttgccaatg ccttcctagg tatttctcac tcaatggccc ataagattgg
    39661 tgcgcaattc cacacagttc acggacgtac aaatgccatc ttgcttccgt acgttatccg
    39721 ttacaacggt acacgtccag ctaagacagc aacatggcct aagtacaact actaccgtgc
    39781 agatgaaaaa taccaagata tcgcacgcat gcttggactt ccagcttcta ctccagaaga
    39841 aggggttgaa tcttacgcaa aagctgtcta cgaactcggt gaacgtattg ggatccaaat
    39901 gaattttaga gaccaaggaa ttgacgaaaa agaatggaaa gaacattctc gtaaattagc
    39961 cttcctggct tatgaagacc aatgttcacc agctaaccca cgtcttccaa tggtagacca
    40021 tatgcaagaa atcatcgaag atgcatacta tggctacaaa gaaagaccag gacgccgtaa
    40081 ataattgttt atcagtctag aagcaagaca aaaactcaat ttgagggaaa gatccagtaa
    40141 tttttctatg ataaaaggca tcctatcaag gtttttgaat acctgatagg atgccttttt
    40201 atgatgttga ggcctttttg ccctttttga aaaactagaa tagaaacaaa atatatagta
    40261 ggttgaaact agaatagtac acatctgctg ctaaaacatt tatagaaatt aattttactt
    40321 tcctgataga gttgttcaca tcttatttca attcactata gtttaattta agagtagtat
    40381 ttactaaggc ccaattaaaa tcaaagagca aactagaaaa cgagaaaacg atgacaaggt
    40441 gtgttgcttt ttgatttcta aagagtataa tgatagatct ctataaaata agtgcgaagg
    40501 aaatgagctt ttatagtcct ttcgttttaa aatactatct cagatattct tatatcgaca
    40561 agaagttttt gagtcattcc ctcatcatac atattaaata aatagtggct cattcaattt
    40621 tttactagaa taataagcta gtatagtaaa ctgaaataag atataaacaa ataaattgga
    40681 gcttaacatc tatttccagc aattttttag aaactgcagt ggactattct aaattcaaca
    40741 cattataaaa actagagtaa aagaaaagga ttggatcttg tgtaatgcag gatccaatcc
    40801 tttcaatcat tttgtccaac ttttggaggt tcctacaatg tagccgtcat taataaagac
    40861 agatgggaac gacagtgttc ctatttattt tgatagagat cgatgaattc tttagatagc
    40921 aactgaataa tctctgttga agccatttgg tcttctgcat gcataaatag caaggagaat
    40981 cctatttttt ctccagtagc ttctttttgt atgagattag agtgaatctt gtgcgcttct
    41041 actaaggagt cttccgcttc ttcaacttta attttcgctt cttttaaatt tcctgcctta
    41101 gctagttgga tggcttcaat aaaggatgat ttggctgctc cactattggc aatgatctga
    41161 aaacagatat attccatttc ttctgtcatc ttatttctcc tatccatgca agtgcttgtt
    41221 ccagaacttt tgctccattc atcattccgt aatcccgcat atcaatggta tctacaggga
    41281 tatttcctgc aatttctttc acagcaagta actcataacg aatttgtggc ccaattagaa
    41341 tgacatctgc ttcatggata ttctttttag cttctgtcat tgattttgct tggatagaaa
    41401 tttcaatccc acgttcagtc gcactttgtt gcattttttt aacaagcata cttgtcgaca
    41461 ttcccgcatt acatactaat aaaatttgtt tcataatctt aaccttccat ttcttgctca
    41521 acaactttgt cattaacttt gataaatgga atgtatagaa gaactccaag tgcaaagatg
    41581 atgaattgaa ctagaactgc tctcacgtcc cctgctgttg ctaaccatgc atttaagaat
    41641 actggtgtag tccaaggaac ttgtataaat gcaggactca tgaatcctgt aactgttgct
    41701 aagtagctga ttaaaatacc aaggactgga actgtgataa atggaatagc taatgaaatg
    41761 ttataaacga ttgggtaacc gaataatact ggttcattga tattgaagat accaggtcca
    41821 aaagataatt tagccacgtt tttagagaca gcattgcgac tcactaagaa tgttgctatt
    41881 aataaacata atgtagatcc actaccaccc attaaagcga atgtttgtat ttgtgatagg
    41941 ttgatgatgt gtggaatggc ttgtccatta tttgctgcag tgatgttttc agtaatgtta
    42001 attaatagta atggttctag gatggcactg taaataactg cttggtgaat accaaatagc
    42061 cataacatat ttcctaaaga gtaaataata atgaccccga ttaagcttgt accaatatga
    42121 cgaattggtt cttgaataaa gattgtaatg attgagatta agttcattcc agttatattg
    42181 aataataatg ctgaaacaac cccaaataag gagatgacgg tcatgactgg aagtaatacg
    42241 ctaaatgatc tactaacagc tggtggaata ttttcaccaa ggttcatttg taaagcttta
    42301 acgtttgata attcaatgaa taattctgtt gcaataatcg ctacgataac cccggcgaac
    42361 attgcgcctg tacctgtgtt gttgaatgaa agaacacctg aaatgtttac cgcatctttt
    42421 gctccgtcag gaactacaga aactgtattt ggcatcatca caattaaaga aactaatgat
    42481 agcattgatg ctgctaacgg gttttcgaaa tctctgtttt tagctaagaa ataaccaacc
    42541 attacagcaa taatcatacc tgaaatactt aaagtaccgt ttgcaattgt tattccccaa
    42601 tattggaatc ttgttaatgt atccccttgg aaaatccact taaataccgt gttgttcaaa
    42661 agaacgatta aacctgccaa aatatataat ggcattactg ttacgaatgc atctcttagg
    42721 gtttttaaat gaatttggtt ccctagttta ccagcaaagg tggcaaattg atctataaat
    42781 tttgagtttt tcatctgaat atctcctctc tttactcctc aatttctact tcaaaaccgt
    42841 tattgtcact tactttgcga taccatcttc ctgagctctt gatggttctc ttttgcgttt
    42901 ctaaatcaac ggagataaat ccgtaacgat tcttatatgc attattccaa gaccagcaat
    42961 caaatgcggt ccaagcgtgg tatccaaaac agtgacttcc ctcttcaatg gctttatgta
    43021 gccatcttaa atgttcttca taaaattcaa tacgatacac gtcatcgata actccatttt
    43081 caccgataaa ccgtgcttcg ttttcaacac ccattccgtt ttcactgata aaccatggaa
    43141 tattatcata ttcttccttc acaatcatag caatatcata aatggctttc ggaaaaattt
    43201 cccaaccacg atatggattc atgcgacgct ccggccattc atactctttg aagtattggt
    43261 ctggcatcca gggcgtctga tattcctcag gatttgcttg tgcttgaaca cgttttggat
    43321 ggtagtagtt tactccaaga aaatcaaccg tatttgattt catcagttga agctcttttt
    43381 cggtatgact ccataacacg ccatctctct ctagctgttt taccaatctt tctgggaaag
    43441 ttcctttaac agctggattc aagaagactt tgttaaagaa gtcatctgta aatcgacttg
    43501 cttctaagtc ttctggagaa ttacttcttg gataagcagg tgtcaagttt aaaataatcc
    43561 caatctttcc atcaagtcct aatgagcgat atagttgaat cacttttgca ctagcaaggt
    43621 ttagattata gatgacttgt acggcctctt ttccctttcc ttttagattt ggataatgga
    43681 aagcatataa gtatcctgct tctggaatga ccattggctc attgaaagtt gtccagtaat
    43741 gaaccttatc tccaaagcat gtgaaagcag tcttggcaaa cttcacgaat aactccacta
    43801 catgtttgct ttcccaacca ccgtattttt gaagaagttc cactggtaaa tcaaaatgat
    43861 gtaaattcat cacaagatcc atctggttct ttttagcttc ttcaatgatg gcattgtaga
    43921 aagcaatacc ttttggatca ggctcacctg tctctaaatt cttgatgagt cgactccatt
    43981 ggatggaagt gcggaaagaa ttaactccaa tttccttcat caagtggaaa tcttcggtgt
    44041 aagtatgaaa aaagttactg gctacaagag gtccgacatt atcgaaaaaa tcttctggat
    44101 gcgttttgaa ccagtagtcc atcacatttt catgtacttt tccatattga ccttctgtct
    44161 gaggtccgct agaagcagct ccccaccaaa acagattagg aaatactaac ttttttttca
    44221 tgctcaacct cctttctatt attctataca taaagtatag cataatttta aaatttgtct
    44281 agacattttt aaaaattgtt tatacatatt ttgtgtttgc ctcatttctt gaactttgtt
    44341 atactactat tagaatatta tagagagaac cagattaaat gagtacaaaa tatttattta
    44401 tttacaatga gattcgtgaa aagattcttt gtaataaata taccatgaac gaacaattgc
    44461 ctgatgaaat gacattagct aaacagtttg cctgtagtcg aatgacgatc aaaaaagctt
    44521 tagacttgtt agtttctgag ggcttaattt ttagaaaacg tgggcaggga acctttgttc
    44581 tctctcgtgg cagctcaaaa agaaaattaa tcgttccaga aagagatatc cggggactga
    44641 caaaaatatc tgaagatgct cattctacaa ttgactcgag gattattcac ttcaaattag
    44701 aatttgcaaa tgaattttta gcagaaaaac tacaggtcgc tttgcagagt ccagtttata
    44761 atatttaccg tctgcgtatt attgacggta aaccttatgt tctggaacaa acttatatga
    44821 gtaccgatgt tattccaggt attactgaag atattttaca aaaatcgatt tacaattaca
    44881 ttgaaggaaa gttaggattg catattgcca gtgctacaaa aatcttgcga gcttcttcta
    44941 gttcagaaaa tgagcaacat tacttgcagc tccttccaac ggaaccggta tttgaagtag
    45001 aacaagtggc ttatttggat aacggaactc cgtttgagta ctcgattagt cgtcatcgct
    45061 atgatttatt tgaatttaat tcttttgcat tacgacattc ctcctaggag aaaatgtgaa
    45121 aatgaagcca atcttttaca ggctctagtt taagaaaaat ttaaaacagg gcaagaaggt
    45181 cccatctatg cttaaatggt ttctcttttc taaataagat ggctttaaaa gagtgatcgt
    45241 tttatccatc atgttgaaaa atatcttcgt atagcttata gagtaggtac tgaaattgtt
    45301 cacctgatct acttcttata gttatttagt tttaaatagt gtttcaaaca ttcttacact
    45361 gacgagaagt ttttgagtct tttcttgtaa cacatatagt atactgaggt tagaatagta
    45421 gattgtgact tctaacaaat tgctagaaat gaatttcaat ctcccaattt atttgttcat
    45481 atcttctttt aatatattaa ataaattctg aatcataatc atttaaaaaa attttatttt
    45541 tttatttttc attacgaata atatagatga aggggaaaga gtatgaaaac agaactgttt
    45601 cttttgctat tagttcaaaa ggagaaaaaa tgaaagtaga aaatatttcg tatagggtgg
    45661 atcatcgtat attgtttgat aatatttctt ttgatacttc gagttcaggc gtgacattaa
    45721 ttactggtaa aaatggtaca ggaaagtcaa ctttactata gtagattgaa actagaatag
    45781 tacacatcta cttctaaaat attgttagaa atcgatttga ctatcctgat ctatttgtcc
    45841 tgttcttatt tcatttcact atatctcaaa ttgagtatga cgaagtgcgc tcccatgtcc
    45901 tgggaacgca ctttcttcat atttttcata ttcttgaatc catcgataaa gactattggg
    45961 atgaattttt aaagttgaac taatcatttt tacaggatga ggtttacagc agagagtttg
    46021 aaggctttat caaaggtttt tcttggcata atgacttttc ctcgtttcca cttaattttg
    46081 tgtctacttt attataccaa gtccaccctt aagttagata ataaatctaa cttaaggaag
    46141 ctagaaggat gagaatccag gtggtcaaga gtcccaaact taagctgatg gggacaccca
    46201 gaataatttg ctttttgaag gcaaggccac gttcctctat attgggaagt gagagttgaa
    46261 tgagagaacc agctgatgaa aagggtgaga tattagtaga tagagcgcca ataacggtgg
    46321 ctgttgtgag taagtgaata tcaatctggg gattttgagc actgatgata gcaatgatgg
    46381 gaaagagggc tggagctaca acggataggg tggaactaaa gagtgacatc actccggcta
    46441 tcacacaaaa gaacagaggt aaccagaaat gaggaatgga tgttgtcatg aggtgcccta
    46501 tcagtgtgac taaacctgac ttgaccgcta gagacattag taagctcatg ccgcagagca
    46561 tgataattgt agcccaggga accttagcta aaatggcttc ttgtttccct aatttgagcc
    46621 ttaaggcgag gcagaccatg agtattgaga caaagccaat atcaaatgtt tttcgataag
    46681 tagctatcca ggcgatgttt gggaaaatga gatgcaacaa gggaaaaagc caaaccaaaa
    46741 ccatgctgct gatcatgagc aaggtggttt gtctttgaac cttgctgagg agtggtggtt
    46801 ggtcaatagt caaggatgag tttgttcttc ccttactata gtgactgtaa caggataata
    46861 aaagcaagac gatgagtggg tagataatgc tgacgataaa gatatgattg ccaagtgaaa
    46921 aagcttgctc ttcccatccc atttgcttaa acaggccttg aaagacaatg cctgagctac
    46981 tggttatcaa attagcccct cctgaagctc cccaattgac ggcttgagct ccaatcaaag
    47041 ggtgtttgtc cgctttttga cagagggtaa tcgctagagg acagcaaacg gccatagtag
    47101 tgaaaaatcc agcacctaaa gcagacaaaa gggttgccat caggtataaa atcatgtaga
    47161 gggcgttagg gtaggtgcgt gtgcggtaga gaatgtgttg agccaaaaca tcaagagtac
    47221 cgttagttat tgcaaagtta taaaagagag agacgctaaa aatggtaaaa aagagtgagg
    47281 ttggccaaaa atgaagaagt tctttggggc ttaatcccat gagagtggtt gcgatgaggt
    47341 aagaaaaagc aatagccagc aggccaatat tgattttggt gcggtaacca attccaatgg
    47401 ctagagcaat ggcgctaatc attattaaat gaatcattga attgtccttt cagttagaat
    47461 atggaaatag gttggcaatt ttggcgctca aaagaccacc tgtttcctat tggtacttga
    47521 ctattataca caaaaaaaat acaattgtct tgacaattgt attgacactt gttagaatta
    47581 aaaatgaggt attcaggttt gtgatttcct atggaagtta atagtaattg cctctaatgc
    47641 ttacaagtga tattaaaaat agaggactta gtgatgtcaa tcatttcaac tgatttaacc
    47701 ccttttcaaa tagatgatac attgaaagca gccttgcgag aagatgttca ttccgaagat
    47761 tacagtacca atgccatttt tgatcatcat ggccaagcca aggtgtcgct ttttgccaag
    47821 gaagctggtg ttttagcggg gctaaccgtt tttcaaaggg tttttaccct atttgatgcc
    47881 gaggtgacct tccagaatcc tcatcaattt aaggatgggg atcgtttgac tagtggcgat
    47941 ttggttttag aaatcatagg ctcggtgaga agtctcttaa catgtgaacg cgttgccttg
    48001 aattttttac aacatttatc agggattgct tcgatgacag ctgcttatgt agaagcctta
    48061 ggcgatgatt gcattaaggt atttgatact cgaaaaacta ctcctaattt acgtcttttt
    48121 gagaaatatg ccgtgagagt tggcggtggc tataatcatc gctttaattt atcagatgct
    48181 atcatgctaa aagacaatca cattgcggca gtaggtagtg ttcaaaaggc aattgctcaa
    48241 gcgcgtgcct atgccccttt tgtgaaaatg gtcgaggtgg aagtggaaag ccttgctgct
    48301 gccgaagaag ctgcggcggc gggtgctgat attatcatgt tggataatat gtcattggaa
    48361 cagattgaac aggccattac cctaattgca ggacgttctc ggattgaatg ttctggaaat
    48421 attgatatga ccactattag ccgttttcgt ggtttagcga ttgattacgt ctccagtggt
    48481 agtttaaccc atagtgctaa gagtcttgat ttttccatga aggggttaac ctaccttgat
    48541 gtctaagttg taaaataaac taacttttta aaggatgtct ttcctctaga acgagtttta
    48601 tgtcagatag tttaaacgcc tctt
//
LOCUS       DAVDFK010000014        40588 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.14, whole genome shotgun sequence.
ACCESSION   DAVDFK010000014 DAVDFK010000000
VERSION     DAVDFK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.14"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(431..844)
                     /gene="ndk"
                     /locus_tag="VUR04_000981"
     CDS             complement(431..844)
                     /gene="ndk"
                     /locus_tag="VUR04_000981"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET5340891.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(955..4632)
                     /gene="rpoC"
                     /locus_tag="VUR04_000982"
     CDS             complement(955..4632)
                     /gene="rpoC"
                     /locus_tag="VUR04_000982"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET5340892.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4665..8276)
                     /gene="rpoB"
                     /locus_tag="VUR04_000983"
     CDS             complement(4665..8276)
                     /gene="rpoB"
                     /locus_tag="VUR04_000983"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET5340893.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8692..8762
                     /locus_tag="VUR04_000984"
     tRNA            8692..8762
                     /locus_tag="VUR04_000984"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8724..8726,aa:Cys,seq:gca)
     gene            complement(8960..10291)
                     /locus_tag="VUR04_000985"
     CDS             complement(8960..10291)
                     /locus_tag="VUR04_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET5340894.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10582..11406)
                     /gene="endA"
                     /locus_tag="VUR04_000986"
     CDS             complement(10582..11406)
                     /gene="endA"
                     /locus_tag="VUR04_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET5340895.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11445..11633)
                     /locus_tag="VUR04_000987"
     CDS             complement(11445..11633)
                     /locus_tag="VUR04_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET5340896.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11626..12909)
                     /gene="murA"
                     /locus_tag="VUR04_000988"
     CDS             complement(11626..12909)
                     /gene="murA"
                     /locus_tag="VUR04_000988"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET5340897.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEANDEDE"
     gene            complement(12933..13163)
                     /locus_tag="VUR04_000989"
     CDS             complement(12933..13163)
                     /locus_tag="VUR04_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET5340898.1"
                     /translation="MIQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13221..14258)
                     /locus_tag="VUR04_000990"
     CDS             complement(13221..14258)
                     /locus_tag="VUR04_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET5340899.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14242..14730)
                     /gene="coaD"
                     /locus_tag="VUR04_000991"
     CDS             complement(14242..14730)
                     /gene="coaD"
                     /locus_tag="VUR04_000991"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET5340900.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14720..15259)
                     /gene="rsmD"
                     /locus_tag="VUR04_000992"
     CDS             complement(14720..15259)
                     /gene="rsmD"
                     /locus_tag="VUR04_000992"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET5340901.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15324..16316)
                     /locus_tag="VUR04_000993"
     CDS             complement(15324..16316)
                     /locus_tag="VUR04_000993"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET5340902.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16428..17111)
                     /locus_tag="VUR04_000994"
     CDS             complement(16428..17111)
                     /locus_tag="VUR04_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET5340903.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17167..17907)
                     /locus_tag="VUR04_000995"
     CDS             complement(17167..17907)
                     /locus_tag="VUR04_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET5340904.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17941..18219
                     /locus_tag="VUR04_000996"
     CDS             17941..18219
                     /locus_tag="VUR04_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET5340905.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18297..19223
                     /gene="yidC"
                     /locus_tag="VUR04_000997"
     CDS             18297..19223
                     /gene="yidC"
                     /locus_tag="VUR04_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET5340906.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19298..20092)
                     /gene="pflA"
                     /locus_tag="VUR04_000998"
     CDS             complement(19298..20092)
                     /gene="pflA"
                     /locus_tag="VUR04_000998"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET5340907.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20218..21468)
                     /locus_tag="VUR04_000999"
     CDS             complement(20218..21468)
                     /locus_tag="VUR04_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET5340908.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21535..22362)
                     /gene="purR"
                     /locus_tag="VUR04_001000"
     CDS             complement(21535..22362)
                     /gene="purR"
                     /locus_tag="VUR04_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET5340909.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22629..23570)
                     /locus_tag="VUR04_001001"
     CDS             complement(22629..23570)
                     /locus_tag="VUR04_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET5340910.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNAPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(23560..24816)
                     /locus_tag="VUR04_001002"
     CDS             complement(23560..24816)
                     /locus_tag="VUR04_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET5340911.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTFASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24818..25480)
                     /locus_tag="VUR04_001003"
     CDS             complement(24818..25480)
                     /locus_tag="VUR04_001003"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET5340912.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25443..26099)
                     /locus_tag="VUR04_001004"
     CDS             complement(25443..26099)
                     /locus_tag="VUR04_001004"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET5340913.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26110..26988)
                     /gene="rsgA"
                     /locus_tag="VUR04_001005"
     CDS             complement(26110..26988)
                     /gene="rsgA"
                     /locus_tag="VUR04_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET5340914.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(26990..27862)
                     /gene="rsmA"
                     /locus_tag="VUR04_001006"
     CDS             complement(26990..27862)
                     /gene="rsmA"
                     /locus_tag="VUR04_001006"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET5340915.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(27993..28301)
                     /locus_tag="VUR04_001007"
     CDS             complement(27993..28301)
                     /locus_tag="VUR04_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340916.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(28294..28935)
                     /locus_tag="VUR04_001008"
     CDS             complement(28294..28935)
                     /locus_tag="VUR04_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340917.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(28937..30967)
                     /locus_tag="VUR04_001009"
     CDS             complement(28937..30967)
                     /locus_tag="VUR04_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5340918.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMTN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLFGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31044..31340)
                     /locus_tag="VUR04_001010"
     CDS             complement(31044..31340)
                     /locus_tag="VUR04_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5340919.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31660..32571)
                     /locus_tag="VUR04_001011"
     CDS             complement(31660..32571)
                     /locus_tag="VUR04_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5340920.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(32643..33203)
                     /gene="rnmV"
                     /locus_tag="VUR04_001012"
     CDS             complement(32643..33203)
                     /gene="rnmV"
                     /locus_tag="VUR04_001012"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET5340921.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33203..33976)
                     /locus_tag="VUR04_001013"
     CDS             complement(33203..33976)
                     /locus_tag="VUR04_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET5340922.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(34281..35180)
                     /locus_tag="VUR04_001014"
     CDS             complement(34281..35180)
                     /locus_tag="VUR04_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET5340923.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKEKV
                     KVAILQANGSALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATP
                     EYKLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESA
                     KNAIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETI
                     GVQAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAAL
                     ASLGLVVATSGFALLGRKTRRRK"
     gene            complement(35464..35598)
                     /gene="rpmH"
                     /locus_tag="VUR04_001015"
     CDS             complement(35464..35598)
                     /gene="rpmH"
                     /locus_tag="VUR04_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET5340924.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35743..36957)
                     /locus_tag="VUR04_001016"
     CDS             complement(35743..36957)
                     /locus_tag="VUR04_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5340925.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37113..37406)
                     /locus_tag="VUR04_001017"
     CDS             complement(37113..37406)
                     /locus_tag="VUR04_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340926.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37568..38020
                     /locus_tag="VUR04_001018"
     CDS             37568..38020
                     /locus_tag="VUR04_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET5340927.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38055..39443)
                     /locus_tag="VUR04_001019"
     CDS             complement(38055..39443)
                     /locus_tag="VUR04_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5340928.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            39509..40471
                     /locus_tag="VUR04_001020"
     CDS             39509..40471
                     /locus_tag="VUR04_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET5340929.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT        11436 a         9484 c         7825 g        11843 t
ORIGIN      
        1 aatgatttaa cacaaaaaga aattattgaa gttctggaaa gatgttgttt cagtattgag
       61 aaaaggtggg aaaaacttgc gattttcaca gagaaaggaa gaaaaagtat agaaatatag
      121 tcaattgaaa caagaacagg ataaaagaac cttttgtgcc atatttttct cctttcgctt
      181 tacaattggc ttgaacacct ttattgtatc gcgtttggag tttttttggt ataaccttcg
      241 acgcgcaccc gcatagcggg tgtttttttg tctcgcacct aacggagcga gacaaactaa
      301 tagtcactta atcaaaaaac gcaccatatc aaaaactaaa aagtttgata tcatgcgtca
      361 tgtcttaaac taattgacta tactttctat tcaaatgagc ttttaaccaa ttgattgagc
      421 caatccactc ttaaaaccaa agagcaattt ctcgcttagc tgactcttct gaatctgaac
      481 catgtacaac attttggata atctcatttt ctccagcagc ttttgcaaaa tcacctcgaa
      541 tagtgcctgg taaagcttct tctggacgag ttgcacccat catggtccgc caagtttcga
      601 ttactttggg accagaaatg acacctacaa gaactggacc tgaagtcatg aattcacgaa
      661 tcggtgggta aaaactctga ccaaccaagt cctgatagtg ctggtcaatc aactcttctg
      721 aaacctgtga acgaaactcc aatttttcga ttgtaaatcc acgttgttcg atgcgcttta
      781 acacttcacc cactagccct ctttttacac catctggttt gatgataaag aatgtttgtt
      841 ccatacccgt ctcctttgtc agcttctttc ttttatttta ccacatttcg tggaaaaatg
      901 gagaaagttt tcagaagaga gaatgagaga accctcgggt tctctcattc tctcttattc
      961 tactgtttct tccacagttt caacggcagt atccacaact acttctgttg tttcttcatt
     1021 tccttcttcc tctactggag gattaaggta ttcttcttcg ttgacagcat gtggttcaag
     1081 gttacggtaa cgggccatac cagtaccagc tgggatgatc ttaccgatga taacattttc
     1141 tttaagtcca aggagatggt ctttcttacc acggatagct gcgtcagtaa ggacacgagt
     1201 tgtttcctgg aaggaagccg ctgacaagaa actgtttgtt tcaagtgagg ctttggtaat
     1261 tcccataagg actgggcgac ctgtcgctgg aactccacct gcgataagga catctttgtt
     1321 ggcatctgta aagtcattga tatccatgag ggtacccatg agaagatctg tatcacctgg
     1381 atccatgaca cggactttac ggatcatttg acgaaccatt acctcgatgt gtttgtcacc
     1441 gatttctacc ccttggctac ggtaaacttt ttgtacttca ccgagaaggt acgtttcaac
     1501 tgacaagaca tcacgaactg caaggagacg ttttggttgg atagaacctt ctgtcagagc
     1561 agcaccacgc gctacttggc ccccaacttc gacacgcata cgagctgtaa atggaacgac
     1621 atattcacct tcgccagttt cacccttaac aaagactttc ttggtacgag ttgatgcatc
     1681 ttcttcgata gcagtaactt gtcctttaac ctctgtaata accgcttccc ctttaggatt
     1741 gcgggcttca aagatttctt ggacacgagg aagaccctga gtgatatcgg tatttgaggc
     1801 aaccccacct gtgtggaagg tacgcattgt aagctgtgta ccaggttccc cgatagattg
     1861 ggcagcgatt gtaccaactg cttcaccaac ttcaaccgca tcaccagtcg ccaagttgat
     1921 accgtaacag tgacggcaga caccgtgacg agtgttacat gtaaatacag aacggatagt
     1981 cacttcttcc acaccagcat tgacaatttc acgcgccttg tcttctgtaa tcaattcatt
     2041 tggaccaata atcactgcac cagtttctgg atgtttaaca gttttcttag tgtaacgacc
     2101 gttgagacgc tcttcgagag actcgatcat ctcttttcct tctgcgatag aacggatcaa
     2161 gagaccacgg tcagttccac agtcgtcctc acggatgata acgtcttggg caacgtcgac
     2221 caaacgacga gtcaagtaac ctgagtcggc tgtcttaagg gccgtatcgg tcataccttt
     2281 acgagcaccg tgagttgaga agaacatttc caataccgac aaaccttcgc ggaagtttga
     2341 aaggattggc aattccatga tacgtccatt cggagcagcc atcagaccac gcataccggc
     2401 aagctgtgag aagtttgaga tgttaccacg ggctccagag tccatcatca taacgattgg
     2461 gttcttagga tcttgattag caatcaagcg tttctcaagt ttttcacggg cagcacgcca
     2521 ttcagctgta acagcattgt aacgctcgtc gtctgtgatc ataccacgac ggaattgttt
     2581 ggtgatttgt tcgacacgtt tgtgtgattc ttcaatgatt tcagccttgt catcaacgac
     2641 tgggatatcg gcaataccca ctgtcaatcc tgcaagagtt gagtggtggt aaccgaggtt
     2701 cttcatgcgg tcaagtaggg cagaagtttc tgttgtacgg aaacgtttga agatttcagc
     2761 gatgatattt ccaaggtttt tcttcttgaa tggagggttg agctcaagat tgctgatagc
     2821 ttccttgata tctccaccaa gtggcaagaa gtatttagct ggaacacctt ctgtcaagtt
     2881 ggcattgttt ggttcttgca agtatggtag cccctctggc atgatatcgt tgaagagaat
     2941 tttaccaact gttgtaagca agaccttatg tctttgctct tctgtccaag gcttgttgag
     3001 gctgtctgtt gcgataccaa cacgtgagtg gaggtgaaca taaccattgc ggtaagccat
     3061 aaccgcttcg tcacggtctt tgaagaccat tccttcacct tcgcgaccag cttcttccat
     3121 ggtcaagtag tagttaccca aaaccatgtc ctgagatgga gtaactaccg gtttcccatc
     3181 tttcgggttc aagatgtgct cagcagctag catgaggata cgagcttctg cttgtgcttc
     3241 ttctgaaagt ggtacgtgga tggccatttg gtccccgtca aagtcagcat tgtaggcttc
     3301 acagacaagt gggtgcaagc gaagagcctt accatcaatc aagactggct cgaaggcttg
     3361 gatacccaaa cggtgaaggg tcggtgcgcg gttcaaaagc actgggtgtt ctttaatcac
     3421 ttcttcaagg atatcccaga tacgctcatc tccgcgttcc accaagcgtt tagctgcttt
     3481 gacgttttgc acgatatcac gggcaacgat ttcacgcatg acaaatggtt taaagagttc
     3541 aatcgccatt tcacgtggca caccacattg gtacatctta agagttggac caacggcgat
     3601 aacggaacgt cctgagaagt caacacgttt accgagcaag ttttgacgga agcgtccttg
     3661 tttaccttta agcatgtggc tcaatgattt caatggacgg ctacctggtc ctgtgattgg
     3721 acgaccacga cgaccattgt caatcaaagc gtcaactgct tcttgaagca tacgcttctc
     3781 attttgaacg atgatacctg gtgcatttaa ctcaagcaaa cgagccaaac ggttgttacg
     3841 gttgataaca cggcggtaaa ggtcattcaa gtcagatgag gcaaaacggc caccatccaa
     3901 ctgcaacatt ggacgaagat ctggtgggat aaccggaagg atgttaagaa tcatccattc
     3961 aggtttgttt ccagacttgt aaaaggcatc caaaacatcc aaacgacgga tggctttgac
     4021 acgtttttgt ccagtagctg ttttcaattc ttctttgagt tcagcaattt ctttttcaag
     4081 atctacttgc ttcaaaaggt cttggatggc ttccgcaccc atcttggcaa caaatgaacc
     4141 ataaccatat tcgcgcaagc gctctcggta ttcgcgctct gtcatgatag acttgtgctc
     4201 aagtggtgta tccttaggat caatcaccac ataagccgca aagtagataa cttcctcgag
     4261 ggcacgaggg ctcatatcaa gggtcaagcc catacggctt ggaatcccct tgaagtacca
     4321 gatgtgagat acaggagctt tcaattcgat atgtcccata cgctcacgac gaactttcgt
     4381 acgcgttact tcaaccccac agcggtcaca aacaattcct ctgtaacgaa tgcgtttgta
     4441 cttaccacaa gcacattccc agtcttttgt aggaccaaag atcacttcat caaagagtcc
     4501 ttcacgttct ggtttcaagg tacgataatt gattgtttca ggttttttga cttctccata
     4561 agaccatgaa cggactttac ttggagaagc tagggtgatt tgcatacttt taaaacgatt
     4621 tacatcaacc actatttctt ccctttctat tctaagtgaa ctgcttattc ttgttcagca
     4681 gcttcttctg ttgcttccgc ttttgttgct ttctcagctt cttcagcttc aaaggctgct
     4741 ttagcctctt gggctgcttt ttcgcgggct ttttcaaggt catctacgtg gatgacatct
     4801 tcgtccattc cttcatccaa gtcgcgaagt tccacttctt ggtcatcttc gtctaggaca
     4861 cgcatgtcaa gaccaagaga ttgcaattct ttgacaagaa ctcggaagga ttctggaaca
     4921 cctggttttg gaattggttt gccttttgta atagcttcat aggctttcaa acgtccgttg
     4981 atatcgtccg acttgtaagt caagatttct tgaaggacat ttgacgcacc gtaggcttca
     5041 agagcccaaa cctccatctc accgaaacgt tgtccaccaa actgagcctt acctccgagt
     5101 ggttgttggg taacagttga gtaaggtccg actgaacgcg cgtgcaattt atcgtcaacc
     5161 atgtggtgga gtttgatcat gtacatgact ccaacagaaa cacggttatc aaatggttca
     5221 cctgtacgtc catcgtaaag gattgtcttg gcatcgctat ccatacctgc ttctttaaca
     5281 gttgaccaaa gatcttcaga acttgctcca tcaaagactg gtgtcgcaat gtgaatacca
     5341 agagtacgag ctgccatacc aaggtgaagc tccataacct gaccgatatt catacgtgat
     5401 ggcaccccaa gtgggttcaa catgatgtcg actggagttc cgtctggaag gtaaggcatg
     5461 tcttctacag gaacgatacg agagacaacc cctttgtttc cgtgacgtcc ggccatttta
     5521 tctccgacct taatcttacg tttttgagcg atgtaaacac gaaccaacat gttaacacct
     5581 gattgcaact catctccatt tacacgtgta aagatcttaa catcacgaac gacaccatcg
     5641 gcaccgtgtg gtacacgaag agaagtatca cgcacttcac gagacttgtc tccaaagata
     5701 gcgtgcaaga gacgttcttc agctgaaaga tctttctcac ccttaggtgt tactttacct
     5761 acaagaatat caccttcttt aacctcagca ccaatacgga taatccccat ttcgtcaagg
     5821 tctttgaggg catcttcacc aacgtttgga atttcgcgag tgatttcttc aggcccaagc
     5881 tttgtatcgc gcgtttctga ttcgtattct tcaaggtgaa cagatgtgta gacatcgtcc
     5941 ttcaccaagc gttcgctcat gataacggca tcctcgaagt tgtaaccttc ccaagtcatg
     6001 taggcaacga ttgggttttg tccaagcgcc atttctccat tttccataga aggtccgtca
     6061 gcgatgaaat cgcctttttc aacgacatca ccaactttta cgagagtgcg ttggttgtaa
     6121 gcagtacctg agtttgaacg acggaatttt tggatgtggt aaacatccaa tgaaccatct
     6181 tcacgacgaa cttctacctt gtcagcatct gcgtaagtaa ctttaccatc atactgagca
     6241 atcacagccg caccagaatc gtgggctgct tggtattcca taccagtacc aacgtaaggt
     6301 gcctgaggat taatcaatgg cacagcctga cgttgcatat tggctcccat gagggcacgg
     6361 ttggagtcat cgttttccaa gaaaggaata catgctgtcg caacggcaac tacctgtttt
     6421 ggtgaaacgt ccatgtagtc aacaatatta gctggatact cttggttgac cccttggtga
     6481 cgtcccatga caatcttctc agcaaaggtt ccatcttcat tcagacgaga gttagcctga
     6541 gctacagtat attcatcttc ttcatcagct gtcaaccaaa caatttcgtt cgtgacaaca
     6601 cctgtttcac ggtcaacctt acggtatggt gtttgaacaa aaccatattt gttcaagtgt
     6661 ccgtaagatg acaagttatt gatcaaaccg atgttaggtc cttcaggtgt ctcgattgga
     6721 cacatacgac catagtgagt gtagtgcacg tcacgtactt catatccagc acggtcacga
     6781 gtcaaaccac caggtcctaa ggctgacaaa cggcgtttgt gagacaactc agaaagcggg
     6841 ttgtgttggt ccatgaactg tgacaactgt gatgaaccaa agaattcttt aactgcagct
     6901 gttacaggac ggatattgat aatttgttgt ggtgtcaaga cttcattgtc ctgaacagac
     6961 atacgttcac ggacattacg ttccatacga gaaagtccca aacgtacttg gttggcaagc
     7021 aattcaccaa ccgcacggat acgacgattt ccaaggtggt cgatatcatc tacacggcca
     7081 agtccttcag ccaagttgag gaagtagctc atctcagcaa ggatatctgc aggagtcacc
     7141 gtacgaacct tgtcatctgg gttagcatta ccaatgatcg ttacgacgcg atctggatca
     7201 gttggagcaa caaccttgaa tttttgaaga acaacaggct cagtcacaac ggctgcatcg
     7261 tttgggatgt agacaatctt gttcaagtcg ccatccaaat ggctttcaat gctttcaatc
     7321 acgctacgag tcataatcgt accagcttct accaagattt ctccagtttc agggtctacc
     7381 aatggctctg caatggtttg gttgagcaaa cgtgttttaa cattgagttt tttattgatt
     7441 ttgtaacgac caactgctgc caagtcatag cgacgtgggt caaagaagcg agccacaagc
     7501 aagctacgtg agctttcagc tgtcttaggc tcacctggac gaaggcgttc gtaaatttct
     7561 ttcaaggctt cgtctgtacg agagtccatt ggattcttgt ggatatcttt ttcaacagtg
     7621 ttgcgaacca attcgctgtc accaaagata tcaaagattt catcatcacc tgagaaacca
     7681 agagcacgaa ccaaggttgt aaatggaatc ttacgagtac ggtcgatacg agtgtaggtg
     7741 atatcttttg agtcgctttc aagttccaac caagctccac ggttagggat aacagttgaa
     7801 ccatagccca ccttaccatt tttgtctact ttgtcgttaa agtaaacacc tggtgagcgg
     7861 accaactgag aaacgataat acgttcacca ccattgatga tgaaagtacc catttctgtc
     7921 atgattggga aatcaccaaa gaaaacttct tgggtcttga tttcgcctgt ttctttattg
     7981 atcaagcgga aggttacaaa aattggtgct gagtagctag catcgtggat acgagcttct
     8041 tctagcgtgt attttggttc cttgatttca tatccaacaa attccaactc cattgtgtct
     8101 gtgaagtttg aaattggcaa tacatcttca aacacttcct taagaccgtg gtctaggaaa
     8161 gctttgaatg agtcagtttg aatttcaatc aaatttggta agtcaagaac ttctttgatt
     8221 cttgaaaaac tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc tgccaagatg
     8281 attctccttt gtaaataagt tccaagcctt gtcaatcagg cttttctaat cgtcatatgg
     8341 ttgtaaaccc cttatcaccg tgtcctcttg acgaattttc agaatcttta agcctctgtt
     8401 acaaatgctc aaaatcttga aaaaaagcac aaaaagagca gctaaatctg actttttcag
     8461 aagatttaac tgctgtgagc cttgtctgga caatatttca gacaaaacct acgacaaatg
     8521 attacccata ttatacccta tttagctaga tttttcaagg ggtttcagta ggtttttggt
     8581 aaattttttc ccatagaaaa cttggcatca cattcgaatc acgctatggt acaaaaaact
     8641 gaaaaaacta ttgactgaaa atcattttca aggtataata ataaacgtta aggcggtata
     8701 gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc
     8761 cttctataac ttgatttatc aggtttcaaa tgaacagaaa gcccaatttg aagggctttt
     8821 cttattttcc ctcgaataaa tacgtataac tttaaaaact tttggagcga gtttgtggca
     8881 gagttctttc catggcataa ttcccttttg aaatcaattg aaaaaagctt cgtcacgcct
     8941 ggtgacaaaa gcctctagtt tattctgttt cttcttctat ttcgacttct gtgatttgga
     9001 cttttacctt ggtaacacgt ccattcttca ctttatcatt ggttaagata aactgtttgt
     9061 tttggctgac caattcatag ctgagtttct cagtcgttgg aatggttccc actcctgtca
     9121 aataataacc agcgatggta tcaacgtcat cactttccag ttcaacatca aagtaattat
     9181 tgaaatcatt gagggtcata gttccttgaa caatgtaggt atcctcgcca atctgatgaa
     9241 catctattgc tgctttgtcc gtttcatcat caatttcacc aacaatttcc tctaagaggt
     9301 cttccaaagt caccaaacca gccataccac cgtattcatc cagcaagatt gccatttgtc
     9361 tttgggtatt tcgcaattct tttagcaagt catccacaaa aatagtttca ggtacaaaaa
     9421 gtggatcttg taaaattctc ttccaaacaa tattgtcaaa accgtccaca aagcctgcct
     9481 taaggagact cttggtgtga atgattccaa ttacattgtc cttatcccca tcataaaccg
     9541 ggatacgaga ataattttgt tttaaaatac tttggataat ggcttgacta tcatcctgaa
     9601 tatccaccat aaaggcatcc gttcgaggaa ccataacctc tcgtgccatc agttcatcga
     9661 gcgaaaagac accttgtagc atctcaatct catcagcatc caatgtttct tcactatttg
     9721 tcagcatata ggcaatttca tcacgggtca tcttttcatc cgcatcatcg aatgacatag
     9781 gagtcaaatg gctcaagaaa ttggtcgaag cagctaaaag ccaaacaaaa ggactgacta
     9841 gttttccgat cccaatgata accggcgctg tacgaattgc caaggcatcc tttagattaa
     9901 gagcgattct cttaggatat aattccccaa aaacgatgga aatataggtc aaaaatgcca
     9961 aggacagaaa agttgccacg gcttgtgctg tttcgccatt cccaagccaa gaggcaatca
    10021 cacgtcctag agtatcagtt aaactcgccc ctgataagat tgtaatcagg gtgattccta
    10081 cctgaatggt tgataaaaag tggttaggat tttctagtac cttcagcagg cggatgtagc
    10141 gtctgtctcc ttcttccgcc ttttgttcaa ctcgggcacg attaagagaa accatggcca
    10201 tttctgtggc tgagaaaaag gcatttaata ccgtcaagat aaacaataaa acaaattgta
    10261 gcaacaaatt ctgactactt gggtcttcca tagttcttct cctaaaatag tatcttatcc
    10321 tttattatat cacaaaattt aatccaatac atattatttt tttcttagcg taacttccat
    10381 ctctctccca aaactggaag ttagtctaag acggatttcc actgatttca cgcgtttttc
    10441 tcatactaaa agctaggttg tgggaaactg gaagttagtt ttagaagtta ctattttttc
    10501 ttagtacctg ttctagccct gcttaaacta gtaaaaagaa ctcctacatc cataagtgac
    10561 ataggagttt aggcttatct tttactgagt tacagttact tctccagttc ggtaatccag
    10621 ttgaagtccc ttttgaacat tgggaactag aacattgaat tccaattctc catccgaaga
    10681 cttggcttca atctgtgaag ctgagggaac taaatcctcg tttgaagcgt agtaaagggt
    10741 tacacggtaa cggacacgct tgttttggtc caaggcttta cgcaccttgc tttcatagta
    10801 gttttgacca gtcgaatact cggcttgtgc ctgatttgcc caggctgtct gaacagcaat
    10861 gtttttagga ttgcttgttg aggcatcaaa accatccaaa ccaccgatta aggcatagcc
    10921 taacaaatga cctctatcga ctgcatgggt ataagagccc tttagattct tgacctgatg
    10981 ccaacctgga ggagtccaag aagttgaacc attcccagtt tctttacgat tcttgtactg
    11041 acgagtggcc ttagacaaga gggcattagc tacggttgga acagtttcct tgcccactgt
    11101 ctttgtttta ttgtcagcgt agggcttact tgaaaccttg gcatctagat ttgttttatt
    11161 accattgacg ataaaagcac ctgagccatt ccactccaga ctccccttta tttgactctt
    11221 gactgcgtct gttaagacac tctctgccaa tgcttgacta ggagcttcag acgcttgttt
    11281 tttctgacta agcttggttt taggactatt aggtgccgac tgcatctgct tgatataata
    11341 gctccctgta gacaaaagca ataacactag cagtccgatt agtgtctgtc ttgttttttt
    11401 gttcatattt ctccttatct ttagaaaaag gctggttctc cagcctaatt tcctgtaaat
    11461 ttatgaatca attcctgcca ttttgccgga gacaggatag cccacggatc ttgacccttg
    11521 cccaagattc catagcctac cattaaaccg attcctaagg ctagaaggcc taaaatcagt
    11581 accagaatga ctaaaagtaa acgcttgatt acgtaacctg atttcttatt catcttcatc
    11641 atttgcctca atccgctgaa tcttagcacc tagttgcgcc aacttctcat ggaaaccgta
    11701 gtaacctcta tccaagtgaa ccaatttacc gaccacagtt tctccctgtg ctaccaaacc
    11761 tgtcaaaatc aaggccgcac tggcacgaag gtcagttgaa agaacttctg ctccctgcaa
    11821 aggctgtcca ccaacaatac gagctgtatc acggataatc tcagaatgca agcccatgcg
    11881 gcgcatctct tctaggtgtt ggaaacgatt ttcaaaaact gtctccacca tggttgattc
    11941 gccttttgca actgtcatca aggctgtaaa ttgagcctgc atatctgttg gaaatcctgg
    12001 gtggggcaag gttttcacat gaacagcttt tagattttct agttgagaac gaacacgaat
    12061 tccttcgtct tcttcaatta cttcaacacc catttcaagt aacttggcaa tcaagggacg
    12121 gttgtgctcc cagacagcgt ctcgaatcaa gacatcacca ccagtcatgg cagcagctac
    12181 cataaaggtt cctgcttcga tacggtcttg gactacattg tgagtcgtac catgaagttt
    12241 ctcaacacca gtaatggtta tagtctctgt accagcacct ttgaccttgg ctcccatttc
    12301 attaaggaga atggctaagt caacaatctc aggctcacgc gcagcattct caatcactgt
    12361 caccccatca gccagagtcg ctgccatcat caagttctgc gttgcaccaa cacttggaaa
    12421 gtccatatag atatgagcgc catgcaagcg ttctgccttg gcttcgatgt aaccagctgt
    12481 ctgactaatc ttaaccccca tagcttccag acctttcaaa tgaagatcaa taggacgact
    12541 accaatcgta caaccacctg gcatggatac cttggcatga cccacacggg caaggattgg
    12601 ccctaataca acgatggagg cgcgcatctt gctgacatac ttgtaagggg cttcctcagt
    12661 gatgtcgcca gtagcatcca ccttgacaag atgagcttcc tcatcaaagt caaccttggc
    12721 attcaaacca ccaactacct gattcataat aaagacatcc gacaaaatcg gaacattctg
    12781 caagacggtc tttccttcac ttgctagaat agtcgctgcc aacaagggta agactgcatt
    12841 ttttgctccc tcgatcgtca cgcttcctac cagacgatta tcgccacctt gaaccacaat
    12901 tttatccata ctcgtttcct ttactcttga ttttataata atcctctaag cgcttcttgc
    12961 cacaaatgat acaggctaat aaagaaagaa ctcaggatgt agcctatgac aatgctaaaa
    13021 aaggctacta ataaacgaac ttttcttgta ttctcatctg tcacttttaa aaccttctcc
    13081 catctaacaa gatcctttaa aaggtaaaaa ctcacataaa taaagagcat atgactactt
    13141 agagtgaata ataattgaat catttgacta ttataccatc ttctctgttt gtgcgctagt
    13201 ttggaaactt cactcaaaaa ttagggattg tttttcaagt aatcaatcgc atcttgtagg
    13261 gttttaacgg gcacgatttt catatccgtc ttgattgttt tagccgcttc tagggctgtt
    13321 tggtagttgt ttttcgcgtc cggatgcgcc ttttgttctt cttcgctaac agggttatca
    13381 ggagcaaaga aaatagcagc acctgcccta gccgaagcta caaccttctt atcaatacct
    13441 ccaatgtctc ccacattacc atcgcggtca atggtacctg taccggcaac aatacgacca
    13501 ttacgaagat ctgggtgagc tatttgagta tagatagcta gactaaacat gagaccagca
    13561 cttgggccgc caataccagc tgttgaaaag ctaattggga cattgctgat tacctctgta
    13621 cgatcaatca agccgattcc aattccattt ttgccatttt ccaaggtgat gatttttcct
    13681 tctgcagact tggtttgccc atcctcttca taggtgacct tgacggaatc ccctaatttt
    13741 tgagaactga cgtaatcaat caagtctttg gaactatcaa aggtctgatc attgactgct
    13801 gtgactgtat cagagatatt gagaatccct ttaaaggttg aattatccgt cacattcaaa
    13861 acataaactc caaagtactt gagttcgata tccttaccag ctgtttttag tccttgatac
    13921 ttggccatat tttgcgatgt ttgcatgtag aattgattga ttcgcataaa ttcaacatcg
    13981 gaagaaccac ctgtagtctc ctgagcacta cgaatatctg taaaaggtgt caaccaagca
    14041 taaatcatat gagctaaagt ggcatgttga acaccaaccg taacgaattg ataggcacca
    14101 gcttccttat cttctgtgtc atttacttta aggacttggc gaatatcttc cgaaccacct
    14161 ggaacctcta tataataagg caagggcact acaaatgcca agaaggtcac aatcaaggcc
    14221 gcaatgacgt ataagggcca tctaatcttt tttttcattt cttatttcct ccaaaatact
    14281 ctcgggaaca tagcaggcaa tatcctgacc aaacttcaaa agctctctaa cgcctgatga
    14341 actgatatag agatgttcag gtcgactatg taaataaata gtctctatat cagaagacag
    14401 ctgatgattg tagtaatcaa aactggcttc atattgcaaa tccgacgcat ttctcaagcc
    14461 tcgcactagg caagtagccc ccagtctttt tgcgacatcg accaccaatt tatcatgaga
    14521 agacacgact ttaacatttc ccaaatgttt cacagccttt tctaaccccc gtttacgatt
    14581 ttcaagaggg agaaatcctt gtttgtgggg attaaaaaaa atacccacat aaagcttatc
    14641 aaagagtctg ctcgcccgtt caatcatatc cagatgccca tttgtcatcg gatcaaatga
    14701 gcctgtgaat aagccaatct tatctgacat agactgtcac cttactaatt ccataaatct
    14761 tttccttcca gatacccaga caggcaatct cttctggaag ttcaacggcc ttatccgtct
    14821 cgcacacaac cataacatct tcagaaaaaa gctctctctc agccattttt tcaatatctg
    14881 ctacgatttg ttccttggca tagggagggt ctaagaaaac gaggtcaaat tccccagata
    14941 cctgttccaa tgccctttct gcatccattt tgaggagttg aaattttcca acttccttgg
    15001 tcatctggat attttcagcc acgatggtct gagccttacg gtctcgctcc accaaaacag
    15061 cactggacat gccacgcgat actgcttcga tagataaacc accactacct gcataaaggt
    15121 ccaagactcg tcccacttca aagtagggac caatcatgtt aaaaatggct cccctaacct
    15181 tatccgaagt aggtcttgtt gtcttgcctt ctagtgtctt gaggggacgt cccccataga
    15241 ttcctgatac gattttcata ctgtttatta taccaaatta tagacaaaaa gagaaagaaa
    15301 accgaacctt gcggttcgat tctctacaaa atattttcgt aagtatcgcg gacttcttga
    15361 ggccaaacac ttgtttgcac ttctccgatg tgtctcttgc gaagtaggaa catggccata
    15421 cgagattgtc caattcctcc accgattgtc aatgggaata ggccattcaa caaagacttg
    15481 tgccattcca attctaagcg gtcttcatca cctgtaattt ccacctgacg tctaagagtt
    15541 tcttcatcta cacgaattcc catagaagac aactcaaagg ctccacctaa agactcattc
    15601 cagacaagaa tatcaccatt tagacccttg tagccattct cagactcgct tgtccagtca
    15661 tcatagtctg gtgcacgtcc atcgtgcggt ttaccatctg gcaactcgcc accgatacca
    15721 atcaaaaaga cggctccaaa ttctttacaa atcgcatttt cacgttcttt aggtgtcaag
    15781 tctgggtagc gttctaccaa ttcttctgta tggataaagg tgatttgttt tggcaagata
    15841 gactcgatgt catagcgggc ttcaacagct agctcagtca ggcgaatagc cttataaatc
    15901 ttctcaactg tttcttttag ataaacgatg ttacgcttac catttggaat aaccttctcc
    15961 cagtcccact ggtcaacata aacagagtgg gttgcatcca aggaatcctc atctggacga
    16021 agggctttca tgtggacaaa gagaccctct ccttcaccaa agccaaaacg agccaaggtg
    16081 tggcgtttcc atttagcaag tgagtgcacc acttcataag tagcatcagg gatttggaga
    16141 accttgaccg atactggatt ttccacacca gacaggttgt cctgcattcc gtcaccgacc
    16201 ttactcaaga taggaccttg aacttcgaca acttctagct tatctttcaa atactgggta
    16261 aaagtgtttt tgacaaagga aatttcttct tgttgatgga taaaactttt cttcatagac
    16321 aactcctcaa aaatttaata aacgtattat acacctattt ccaagaaaag aaaagagaaa
    16381 atttaaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga
    16441 ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc
    16501 attgacacca cccagcctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc
    16561 ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata
    16621 taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg
    16681 agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa aataccaact
    16741 gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga
    16801 gtatagaaag ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat
    16861 actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc
    16921 aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac
    16981 tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga
    17041 ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata
    17101 gtgtgattca tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag
    17161 ttaaaattag cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc
    17221 ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact
    17281 aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct
    17341 gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt
    17401 ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg
    17461 catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc
    17521 tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac
    17581 atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt cttctctttg
    17641 aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc
    17701 tgacacccag acagtttgcg aaaaagtagc taactgatct cgataatttt ctagggtaaa
    17761 gattttctca atcgtcactc cagcttgaac agcttcttca aacaagtgcc agccttcaat
    17821 caaataggct gacttgcggt attttttttg gtgtaatttc ttagcatttt ttaccacaga
    17881 attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt
    17941 atgcaaaagg ttagaatgat tgcccaaggt agggtgcagg gagtcggctt tcgttggggt
    18001 gtttatagcc tggcccttga aatcggtggc atcacaggtc gggtatggaa taacgacgat
    18061 ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa
    18121 gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc
    18181 aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat
    18241 tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga
    18301 aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg
    18361 gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg
    18421 gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg
    18481 tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc
    18541 aatcatggaa ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc
    18601 cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag
    18661 ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc
    18721 ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag
    18781 gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg
    18841 cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacgga gtagaagatg
    18901 aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct
    18961 tctccctctt ctcaccagct agtgtcacac tttactgggt tgtcggtggt ttcatgatga
    19021 ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg
    19081 aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag
    19141 acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg
    19201 ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg
    19261 caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat
    19321 aatcttgata actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg
    19381 gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca
    19441 tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac
    19501 caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc
    19561 agacaggttt tccaatatct gatagatact gggcacaagc caagatattt ttattagttt
    19621 ggctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt
    19681 cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa
    19741 gagcacaggt atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa
    19801 tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc
    19861 cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg
    19921 acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac
    19981 agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg
    20041 tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac
    20101 cttccttgaa aacgttttat agttttatta tatcacgact tgaaggaaaa acaagatttt
    20161 tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta
    20221 ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg
    20281 gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt
    20341 atactggtag cccattgaaa atccgtgggc acctgtatca tgaattacca gcaaatcacc
    20401 gatttctgta tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga
    20461 accaaccaca tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg
    20521 gtaagctccg tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata
    20581 ggtacggtag gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag
    20641 cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac
    20701 ttcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc
    20761 tggacgataa ttaacaccaa taccgccaga aagattgata aagtctagcg aaatgcccaa
    20821 cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag
    20881 atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc
    20941 cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc
    21001 aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga
    21061 gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa
    21121 gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga
    21181 agagaacata atctcagaac ccagaaagtc cagcttatgg ctcatcaaaa gctctacata
    21241 actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg
    21301 agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac
    21361 ggctcttgcc ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc
    21421 ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct
    21481 attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt
    21541 atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt
    21601 ggttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc
    21661 cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc
    21721 attgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt
    21781 aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata
    21841 gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga
    21901 gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat
    21961 aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa
    22021 gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc
    22081 actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat
    22141 agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc
    22201 aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga
    22261 ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat taatcaaata
    22321 gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat
    22381 ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg
    22441 ttttgagatt gtcaatagaa ccgacaaacc ctgtaatata cctgcatata tacatacgac
    22501 aaggcgatac taccctagtt tgaagagatt ttcgaagagt attcattttt gtcttttact
    22561 tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc
    22621 ttaaattatt aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta
    22681 ttggacatct ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca
    22741 tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg gactggactt
    22801 ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc
    22861 ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc aatcagagcg
    22921 atatgtccaa gaagattgcc tctgaccgtg tactcggtct ggtctggtcc cgtcaactcg
    22981 atgaccttag ccaagtcgtg caacataatc cccgcataga gcagactctt attgagctga
    23041 ggataaactt cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg ataagccaac
    23101 cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca
    23161 tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc
    23221 atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg
    23281 gctggggcat tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg
    23341 gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc
    23401 tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg
    23461 aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt
    23521 aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac taatcttcat attcttcctc
    23581 attttcttga aaatggagta gatcaagcgc aggctcgcct tctgacaact caatgtgacg
    23641 gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc
    23701 atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt
    23761 gacactggca aaagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa
    23821 accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa cgataatctg
    23881 ttcttcccgt ctcaaatcat caaagaagac cggattgcgc acaatctctg aataaagacc
    23941 ttctgtcgga acaaacaaga ttccaaaatt ggttgtccga ggcggtgcta tgtacttgct
    24001 cttgatatcc ttggcaaagc gcttgacgct tgctaggagt gacttacgac agcgttcaat
    24061 ctcatccttg tcacctgtct cataggcttc ttccaagcgg taataatctg ccagtggaaa
    24121 cttagagtca attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc
    24181 atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg
    24241 tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt
    24301 ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc
    24361 aaggccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg
    24421 tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg
    24481 ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag
    24541 attatctgtc atttcttgac ggacttgggt cagaccttgg tgcaattcaa tccgcacttc
    24601 ttgcaaacgg tcgctgacaa ccacttccaa atctttttgg tctaactggc tggcttgtct
    24661 ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct
    24721 cttacttaag tgtttctcct gcctatcctg cctttgccaa atcagaaaga gaccagctag
    24781 attggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc ttactatgca
    24841 gcacaaccac atagccatct gggcaagtca cagaaacttc cctatctata tattcgttag
    24901 aagcgtacac ttttttaaag aaaaaatttt cctctgtcaa ctcatacttg gctccaagaa
    24961 tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt
    25021 ctagctgact gattccttct ggacaataag taatcaagtt ttgcccatcc tcaatttcta
    25081 tttgatgcat atagggtgcc aacttaggat tgctaggcag aaagacattg gccaacatat
    25141 ggtcaatacg gccacccaag gcaccgaaaa tagtaacctg agcctgagga ttttgcttaa
    25201 agatggtcaa gagagccaat tccaaatcag tatcatcttt ttctggtcgg gcttggacaa
    25261 aatactgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatctc
    25321 cgactgctag agcaagaggt aagtcttctt ccaagaccca gagcgagcct cgatccaccc
    25381 caacaaaagc atcaaaatct gtccgataat gaccgcggtt tccgcctgca aaaacggcaa
    25441 ccctagtcca gttgttttct gagagtttgt actcgctcat tgacatctcc cttaaagaca
    25501 taggaacctg ctacaaaaac ggtcgcacca gcttctttag cttgggcaat agtttggtca
    25561 tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc
    25621 aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta
    25681 accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat
    25741 gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg
    25801 ccatgaatat gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcgcgcgca
    25861 aagtcttcca gatggtgttc aggattcgcc accatcaagt gacagtcaaa gaccatctta
    25921 ctatgtggac gaagtgcttc aaccacacct gcaccaaaac tgatttgtgg cacaaaatga
    25981 ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca
    26041 cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata
    26101 ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc tacgattttc
    26161 aatttcacta aggaattgca ggtaattatc aaaacggaag gttgcaataa caccctcttc
    26221 aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca
    26281 atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac
    26341 ttcatagtcc agagatgaaa agcctggtgt atctgcgatt ttacccccgt tgagattgta
    26401 aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt
    26461 ttcaagattg aggtctggta cgagtttatt gagaagagtt gacttcccaa cacctgtctg
    26521 ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac
    26581 aaagtcatag ccgatgtcac cataggtctg ccggtaaaaa tccagttctc ccctatcttc
    26641 caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac
    26701 caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac
    26761 agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt
    26821 taggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg
    26881 ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact
    26941 ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt
    27001 gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca
    27061 cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag
    27121 tcttaccaaa gtaacctgtc aagttattcc acaaggtctt acggcgatgg ataaaactag
    27181 ccttggaaac cttaaagaag aagttctcat cttccactgc tacagctggc tctggacggc
    27241 gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca
    27301 cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag
    27361 ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa
    27421 actcactaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt
    27481 aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt
    27541 gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca aaatcacgca
    27601 gggtatctgc caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg
    27661 cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg atgacattga
    27721 cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcagga
    27781 aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca
    27841 cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac
    27901 acattcccct tgtattttgg gaatgaaaat cataccaaaa aactaccttt cctcatgaag
    27961 aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca
    28021 aaaaaatcag cttcttgata acttcgattt tcgggtaggg tcaaatccac atcctcctcc
    28081 acatcatcca ctgtcagttc aaccgtctga ggtaaatttt tcaaacgata atgcttttgc
    28141 ctttgccctt caatactagc aaaatcaagc aaatagccat gcactcggat ttgaaccaaa
    28201 aggagatgat tggtcatatt ttccatgatg aggatatctt ctaaaccacc tctggcacta
    28261 ggataatcag ataccctgcg aatacggatt ttttcacaca tgagcaagtt tcctcatatc
    28321 aatgatttca tcagccttat tccagactag gggattatgg gtcgcaatga tgatcattcg
    28381 attttcatct ttcaaatcca ccaagagatt cataacctcc tctgaatttt caggatcaag
    28441 agctgctgtt ggttcatctg ccaaaatcaa gggtggattt ttcaaaatag tcttagcaag
    28501 ggcaactcgt tgggcctctc ccccagataa agtatagatt ttttgttcta aatccaaata
    28561 ccctagatta actttttcta aagcccccac ttgcctttcc aaacgttcta cttttgagat
    28621 tttctgacca acaaaaccca aatccaaatt ttctttgatt gattggtttt ctaagaggcc
    28681 gaaattttga aagagatagc ccatctggtc tcgaaaatac tcacgagtgg gaatggtttt
    28741 taaatctttc ccctgataga gaacccttcc accatctatc ttttctagct ttcccaagat
    28801 attcagcagc gtcgtctttc cgcttccact ctttccgatt aaggcataaa ccttgccctt
    28861 ctccagcttg agattcaaac cagagaaaat cgcgcggtca ttaaatttct tttccaatcc
    28921 ttgaatatca atcatcttat tttcctttca atactgccat gctaccagct tcttcttttt
    28981 tgtcctgcct tactaaaatc aagagggcgt taagcgtaaa caaagctaca actagagcgc
    29041 taatcaaacc atctcttgtc aaaatactag ataggactaa gccaaacaag agaactcctc
    29101 cttgcgccag taaatacttg ccatgaagct catagattgt cataccagca agacgtttaa
    29161 tcataagctc ccgtctgaac tgctcaaaat agagaagatt catggaatca aataacaaga
    29221 tagccgtaga cagggtcaaa atcgtcccaa taaggagaga gtaaaactcc acccgtttgt
    29281 catttagtac cttggcaaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
    29341 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
    29401 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
    29461 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
    29521 ggaaacgttc ctgtcctgtt tctgtaaaag ctagccttac ctgtgggagg tagtgtttct
    29581 gactcgtcac ttctacactt tcagatgaaa aattttgcag gtaatctgta aacaatcctt
    29641 ggtagtagac agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
    29701 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
    29761 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
    29821 ctaggtccac ttctgctcca tctgagaaat tgtcaacatt gctcataata taaaaagagt
    29881 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
    29941 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
    30001 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
    30061 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
    30121 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
    30181 caagtagata gacgacactt agtaaggtag aaatccctgc caaggtcaat ccatagagta
    30241 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa ggcaccttga taccagagaa
    30301 tccccaatcc caaaagactg gataccagca ctgagcagat aagctgtctc acatcttcta
    30361 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgctt
    30421 gacgaaggga ttttatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
    30481 ctaaactcag tagcaccata ggggtggccg tcaatagtaa gactatcgaa aatggatctt
    30541 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
    30601 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
    30661 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
    30721 agcgtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
    30781 ctaccgccaa gtgactcaaa gcctctgtca cctcttcgcg actagctact ggttgatttg
    30841 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
    30901 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
    30961 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccaagtaaag
    31021 ctaaacaata gggctatacc attctaaaca ttatagtaga atgcaacttt ctctccccaa
    31081 gaagtacgaa tccatgcacg agaagtccct ccagcaccag catatccctt gtcagatgaa
    31141 ccagtttttc tgctaacaac tgttgaacta tggtattttg aagggtgata gtagtttgag
    31201 taagcaccac cgttacctga accataagtc caaacaccac cttctgggta ttgaacggct
    31261 gcagaggcaa ctgctacact tccacctaat gttgctgcaa tgctcgctac aagagctaat
    31321 tttttaactg tttgtttcat attgatactc ctctattttt gattacaaga ttgttgagtt
    31381 acttgctcct ctttccatta tcaacgttga tactattata ttaccaaatg atattctaaa
    31441 attatttgtt tttctctaaa ttgtcaaaat agcaccctga aatgaacttt tatagtcatt
    31501 atactccatc tttatcacac tatcaaggac atcaatgtcc ttaaaatcta actatttcat
    31561 attattttta gcttatatct aaaaaaacag ttctaaagac gaactttaga actgttttga
    31621 tacgaggaca aggacatttt tgtcactgat tcactatgtt tataaatatt tttttaaatc
    31681 ttcttgccat tgtttttcta acatagtaac taaataagaa ttttctatta tatcagcaaa
    31741 tagcttcgat ttctgataga actgttcggc agaaacataa tcattgttta ttattagaga
    31801 taatttccac tccaacatta atataattgg tttcttctgg aaatcttgtg ttttttccat
    31861 tatatgatta aggctaaaga tataagctcc tagtgaatca taagatgaca agttatccaa
    31921 acaggctaga cccgaaaaca aagtgttact taaagcaaac agatattctg gtgcaattaa
    31981 ttctacatga tttgtcaaac gaactaaaaa cgaatgaatt ctgttaattt cttcaatctg
    32041 attttgacct tgttttatct ttgtaagcac tatagcaaaa tataagttga taacttctaa
    32101 ttcatttatc aaaaacaatt ccttatcata aattgtttta aaataatcgt ccagtacggt
    32161 ttccccgtat tctggtcgtc cacttcgaat aacatctatc gttgctctag tagcttcaaa
    32221 ccatactttt tcctcattag gaagttgctc ataaaataaa tcctctatct cttccaaaca
    32281 cgcttccttc ttatcgtact cctcttcttt accatagatt ggttcacgta aaatctggta
    32341 tttcaattct aaataagcag aaggaagagc tgaaaaatcc ggcataaggc tataaactgg
    32401 aactcctagc cggcgagcaa tatagtctaa cttgggcaaa ctcggttgcg aagctccact
    32461 ttcaattcgc gacagttgac gaactgtcag ttcttgctca tctccacaaa aatctggacg
    32521 actaattcct ttttctatcc gaatctcttt aattttttga ccaattaaca tcagacgcct
    32581 cctcttctac ctgcttcgaa aaatactgtg aaacttaaaa aattgtaacg gtcacatctt
    32641 tcctactcat aagatttcat agcttcttcc acttctgcca aagtaacccc aaacaactct
    32701 aggcgtttga ggagttgctt gccgttagaa tagccgattc ggagagtctc tccgagatat
    32761 tccctacgct tacggctgtc tgcccctact agaaaaccaa ggcgaatcaa gtcgctacga
    32821 ctaatgtcaa actgactctc atgttcaaat tgttctgtca cctgagctag agccgttttc
    32881 aggtcttcat agctggcatg ctcaattccc agagaacgcc ccttggtctt ggacttggga
    32941 acagcttcat ctcgcttgag aaaggcatgc tgaactgttg gaatggctgt catgatcatg
    33001 cgccgaatcc gttctccatt aaaatctggg tctgtaaaga caatgactcc atgacgttgg
    33061 tgcaggcgct gaatccgctc tatatcctga tcattgatgg cagaacctcg agtctcatag
    33121 gtctccacat cgaaataacg cttgagattg accgtatcat cacgcccttc aaccacaatt
    33181 acttgggaaa ttttctcttt cattacttgc tgtccaatcc aaaaatgcgt tctgcatttg
    33241 cagtcgttgc cgccgctagc tcttctgtcg tcataccacg caagtcagcg ataaagtcca
    33301 ccacatagcg agtataggct gttttatttt cacggccacg cttgggtaca ggtgctaagt
    33361 aaggcgcatc tgtttccacc aacatcttgt ccaaaggtaa ctctttagct gcttcttgga
    33421 ggtcagttgc cttcttgaaa gtcaccactc ctgagaagga aatggtcata ccaagatcca
    33481 caaacttctc tgcccactca agcgtccctg aaaatgaatg catgatacca ccacgaggac
    33541 caacgccctc actcttgata atctcatagg tatcttccag cgcatcacgg gtatggacaa
    33601 caaaaggcaa atccaagtcc ttagatagct gaatctgacg gcgaaaaacc tgctcctgca
    33661 cctctttggg cgctgtcatc caatggtagt ctaagccaat ttcacctaaa gccacaacct
    33721 tggaatgttt taacttatcc aacaagtaag cctcaacttc ctctgtataa gtaccagctt
    33781 ctgtaggatg ccaaccaata gtcgcataga gctgctcata ctcatctacc aactccaagg
    33841 catgctcaat cgtcggttta tcaaaaccaa caatattcat ctgtgtcaca cccatctcat
    33901 cagccaaggc aatttcttct gcctcacgac ctgcaaattc ttctacattc aagtgtgtat
    33961 gtgtatcaaa aatcatctct tctaacctcg ttttctatct tctattatac caaaaaagag
    34021 gaggggcacc taatttttcg gtttcccctc ctctcttcaa tagagagcta ttctgctatc
    34081 ttttctatcc gatattgccc atctcctatt ccacagttag agacagaaga gattggctac
    34141 attgatagaa tattcctatt cagctaaagt atgtgattat cttgggttct cacttttctc
    34201 acccatcact aggattgatg acttctcaaa atccccctta taatctaact ttaagtagag
    34261 aatagaattt tctagctgtt ctattttcta cgtctagtct ttcttcctag caaagcaaaa
    34321 ccacttgttg ccaccactag accaagacta gcaagtgctg cacttgatgc tgaacctgtg
    34381 ttaggtaatt gtttgccagc aggtgactgg taggtaacat cttgcattgt tcctgcagtt
    34441 gcttgcggtg cacttgttgt cttaggagca gcattaggag ccactggtct cttaggaact
    34501 gtaaccatgg caatggcttg cactccaatc gtttctgctt ccttcacatc ttccatagtt
    34561 ttcgcatttt caatctcttt gagagctgct tgtttttctg cttccactct tgctaaaagt
    34621 tctgcttttt ctttatcaga aagcggtgcg cctttgattt catcctgctt gttcttggct
    34681 gctttttcaa tggcattttt agctgattct ttttcagtag ctaattgctt agaagcttgt
    34741 gattgagctg agttttgtga acctgtgtga gctgatccac ccgcctggct accaccgcct
    34801 gcattcgcat tagcatctga acttccagta ttgcctccct tatctccacc tggtgtattt
    34861 tctagcttat actctggtgt agcttcttga gttacagatt cacctttcgc agattgttga
    34921 actgtatctt ttcctagaat cgtcactact gaaccatctg ggaatgtgat tgttgctgta
    34981 ccatatccag ctacattgat tgtcgctccg tctaatgctg aaccatttgc ttgtaaaata
    35041 gcaaccttaa ctttttcttt ttcttcatct gttaaatgag ttatatcttt tacatctact
    35101 ctttgagcag gtgctttaac agttgatttt tcagcagtcg gtttagtgct atcttgtgct
    35161 tttggatctt gtgctaccaa ttgatttcct ggaattgtaa tagctgaacc atctttaaag
    35221 acgattgttg ctgtaccatc tccacctact tcaactttat agtaaaataa aataataaca
    35281 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa cagaggtgta
    35341 ctattctagt ttcaatctac tgtaacatcg cttccgaatc catttgcatc tactgaactt
    35401 ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata gaattcgttt
    35461 ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata cgcgacgacc
    35521 atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa gtttacttgg
    35581 ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt ttagccggct
    35641 ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc acttttgtca
    35701 atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac gatactgttt
    35761 caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag gaaggtaaac
    35821 gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca agagaacctt
    35881 ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt acatattgcg
    35941 gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca aacctggaat
    36001 atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac caggaagaag
    36061 caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt gggccaaaac
    36121 gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc ccttaacatg
    36181 agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc ggtgggattt
    36241 tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca caggcgtatg
    36301 cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa tcaaatcgtt
    36361 ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg ctccagttgg
    36421 gttatttgga ttgataagga cgattgcctt ggtattggaa gtgatttttg acttgatatc
    36481 gtcaatatct gggtaccatt caacagcttc atcacagata tagtgaacgg catttcctcc
    36541 agctaggctg acagccgccg tccatagagg atagtctggc attggcacta agacctcatc
    36601 cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac catttccaag
    36661 gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact gcatgatggc
    36721 cttacgggct gagaaaattc ctttggagtc agaatagcct tcactatcac gcgcattcat
    36781 aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg gatttcctgt
    36841 attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt ccaatacagg
    36901 accacggata tcataagcaa catgctctaa cttactagac ttgttatatt ctttcatctt
    36961 gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg cgacaagttt
    37021 actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg aggttaagaa
    37081 cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa acctagaaaa
    37141 agcaagccta gaaaggagtc ataaagaaga ttaaacatga ggaaaagccc ccatatcatc
    37201 aagtaatccc aacgcccact tcgttttgca actagaaata agattagatg gtagagtaca
    37261 tgaaaaacta aaaatccaat aaaacttgga taaagaagcg gtaccagact ctctaattga
    37321 cagatcatga tcacttctac caagactgaa actaggataa ttccataata aaggaaattt
    37381 gatttttgaa aagagttttt catcattctc ccttccttca cttctttcct gctatccttt
    37441 cttttatttt atcatatatt tatatagagt ttaagcccta atattctttt gaaaaatact
    37501 ttttttgctt tacttctata gtgaaaaggt ttacaattat agtaagaaaa tttcaggagg
    37561 tttcattatg gcacaacgtt accaaaatat catggtcgca atcgatggtt ctaaggaagc
    37621 ggacttggct tttgtcaagg gagttcattc tgctctacga aacgacgcta aactcaccat
    37681 cgcacatgtc attgacacac gcgctctcca aagcgtatcc acctttgatg ctgaagttta
    37741 cgaagaactc caagtcgacg ctgaaagtct gatgaaagag tacgaaaaac gtgctaaaga
    37801 tgctggggta gcagatgttc atatcgtcat tgaaatggga aatccaaaga ccctgctagc
    37861 acgtactatt ccagatgccg aggaagtgga cctcatcctc gttggcgcaa ctggtctcaa
    37921 cgcctttgaa cgcctcttgg tcggctcttc atctgaatac atactccgcc atgctaaggt
    37981 cgatttgctg gttgtgagag aacaagaaaa aaccttataa tcacaaagaa aaggagcccc
    38041 tagctccttt ttgtttacga tttatttctc tctttatggc gttcgtaagc cttgagctgg
    38101 cgctgcagtt cctttttaat agcaggttct ggagcatatt tttcttccca attatctggt
    38161 tttaagattt tatgggtcac tggatcaaaa tgagccttgc catctggaaa aattttcccc
    38221 atattggcct gatggacaat atcaaaaata cgttctgggt ccacccccat caagacaaaa
    38281 ctgccgtagg tgaagtaaag cgtgtcaatc aaggcatcca cttgccctat caaatcttgc
    38341 tgagcaggtg tcttcttggc tactttatct gctgccttat caagggcctg atgaagttgc
    38401 gatacagctt gaccaaaatc ttcttcagaa ggactggctg ctcgaacaaa ctccaccaat
    38461 tcttctattt taaaaccagc cctatgggtt gcaccctcta aatcccaagc tcgaggttct
    38521 tcttgggttc gttcatccat catgtggtgg aaggtcttga ccttattgaa atgatagtca
    38581 cggctgacaa agactttttc tgaagacaaa acaccaaaat gttccaaggc cttgtggatc
    38641 ccatcttgtt gattgctagt ggtaatgtgc ttggcagctt ccttgacact gctactacca
    38701 tttcccatag cgaccgacat accgacgcca gccagcattt caaggtcatt atctgagtca
    38761 ccaaaagcca tgacttgatt gaggtcaaag ccatattctt tcccaactcg gcgaatgcct
    38821 tctaatttag aatttccctg attgatgaca tccgatgcaa aaggattgct acgtgtcaat
    38881 ttcaagtctt caaaatcagc tgccgccttc tcagattctt ctggtgtcat cagcatcaaa
    38941 acttggtaga taggctgatt catcaggtga agcaggtcct cttccttttg gggaacaacc
    39001 ttgctgacca tgcgattaaa agactgactc accgtccgag ttaaaacaga gggaacgaag
    39061 cgactaattc gttgggaaaa agaacccaga ccaaaggaca tgattttaga acccaacatg
    39121 gcatccttgg tccctagggc aatctccgtg ccctcttttt tagcatagct aattagatgg
    39181 cgcaaatgta acttggaaat agggctcgtg aacaagactc tgtctttact aaagatatac
    39241 tggccattat aggttaccgc aaaatccaga tccaaatcgt ccatcaattc cttaacaaaa
    39301 aaaggtcctc gccctgtcgc tacgccaact agtacccctt gttctttgac aatcttaatc
    39361 gcatccttag tggatttcaa aacactcttg cgattgttga ccaaggttcc atcgatatca
    39421 aaaaaaacag ctttgacttc catcctatcc caatctcccc ttttgtgata caatgattat
    39481 accacatttc agaaagagtt agtaaatcat gcctaagaaa atccttgttt tacatacggg
    39541 tggaactatt tccatgcagg ccgatgcttc tggcgctgtt gtgacgagtt cagataatcc
    39601 catgaaccat gtgtccaacc cacttgaagg aatccaagtc cacgccttgg acttttttaa
    39661 ccttccaagt ccccatatca aacccaaaca tatgctggtc ctctaccaga aaattaaaga
    39721 ggaagcagat aactacgatg gagtggtgat cacacacgga accgatactt tagaggaaac
    39781 agcctatttc cttgatacca tggaagttcc ccatatgcct atcgttctaa caggagccat
    39841 gcgtagctcc aatgagctcg gtagtgatgg tgtttataat tacctaagtg ctttacgagt
    39901 ggccagtgat gacagggctg ctgacaaagg agttttggtc gttatgaacg atgaaatcca
    39961 cgctgccaag tatgtcacca aaacacatac gactaatgtc aacaccttcc agactccaac
    40021 acatggcccc ctcggtctca tcatgaaaca ggaaatcctc tacttcaaaa cagctgaacc
    40081 tcgtgttcgc tttgaccttg atcacataca aggtttagtc cctatcatct cggcttatgc
    40141 tggtatgaca gatgagctga ttgatatgct ggatttagaa cacttggacg gtttgattat
    40201 ccaagccttc ggagctggta atattcccaa agaaacggct caaaaattag aaagccttct
    40261 gcaaaaagga atcccagtcg ctctggtatc acgatgcttt aacggtattg ccgagcctgt
    40321 ttatgcctac cagggtgggg gcgtacagtt gcaaaaagca ggcgttttct ttgttaaaga
    40381 actcaacgcc caaaaagccc gcttgaaact cctcatcgcc ctcaatgccg gactaacagg
    40441 acaggctttg aaagactata tggaaggcta atactcttcg aaaatctctg caaaccacgt
    40501 cacgtcgcct taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa
    40561 acatgttttg agctgacttc gtcagttt
//
LOCUS       DAVDFK010000015        39451 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.15, whole genome shotgun sequence.
ACCESSION   DAVDFK010000015 DAVDFK010000000
VERSION     DAVDFK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.15"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(187..1167)
                     /gene="dusB"
                     /locus_tag="VUR04_001021"
     CDS             complement(187..1167)
                     /gene="dusB"
                     /locus_tag="VUR04_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET5340930.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1154..2026)
                     /gene="hslO"
                     /locus_tag="VUR04_001022"
     CDS             complement(1154..2026)
                     /gene="hslO"
                     /locus_tag="VUR04_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET5340931.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2191..3618
                     /locus_tag="VUR04_001023"
     CDS             2191..3618
                     /locus_tag="VUR04_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5340932.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QPPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3777..5285
                     /gene="glpK"
                     /locus_tag="VUR04_001024"
     CDS             3777..5285
                     /gene="glpK"
                     /locus_tag="VUR04_001024"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET5340933.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5327..7153
                     /gene="glpO"
                     /locus_tag="VUR04_001025"
     CDS             5327..7153
                     /gene="glpO"
                     /locus_tag="VUR04_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET5340934.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7223..7927
                     /locus_tag="VUR04_001026"
     CDS             7223..7927
                     /locus_tag="VUR04_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET5340935.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8175..8321
                     /locus_tag="VUR04_001027"
     CDS             8175..8321
                     /locus_tag="VUR04_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004247184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340936.1"
                     /translation="MLVEFHKSQGTLETPEAQAEIAQKREEIEQRRAELEDKKQELLN
                     RLNK"
     gene            complement(8408..8668)
                     /locus_tag="VUR04_001028"
     CDS             complement(8408..8668)
                     /locus_tag="VUR04_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340937.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(8723..9067)
                     /locus_tag="VUR04_001029"
     CDS             complement(8723..9067)
                     /locus_tag="VUR04_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340938.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            10162..11439
                     /gene="ltrA"
                     /locus_tag="VUR04_001030"
                     /pseudo
     CDS             10162..11439
                     /gene="ltrA"
                     /locus_tag="VUR04_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            11895..13073
                     /locus_tag="VUR04_001031"
     CDS             11895..13073
                     /locus_tag="VUR04_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5340939.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13387..13518
                     /locus_tag="VUR04_001032"
     CDS             13387..13518
                     /locus_tag="VUR04_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET5340940.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13539..15089
                     /gene="dltA"
                     /locus_tag="VUR04_001033"
     CDS             13539..15089
                     /gene="dltA"
                     /locus_tag="VUR04_001033"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET5340941.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQRHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15086..16330
                     /gene="dltB"
                     /locus_tag="VUR04_001034"
     CDS             15086..16330
                     /gene="dltB"
                     /locus_tag="VUR04_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET5340942.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16344..16583
                     /gene="dltC"
                     /locus_tag="VUR04_001035"
     CDS             16344..16583
                     /gene="dltC"
                     /locus_tag="VUR04_001035"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET5340943.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16576..17844
                     /gene="dltD"
                     /locus_tag="VUR04_001036"
     CDS             16576..17844
                     /gene="dltD"
                     /locus_tag="VUR04_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET5340944.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKNQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            17999..18439
                     /gene="adcR"
                     /locus_tag="VUR04_001037"
     CDS             17999..18439
                     /gene="adcR"
                     /locus_tag="VUR04_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET5340945.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18439..19143
                     /locus_tag="VUR04_001038"
     CDS             18439..19143
                     /locus_tag="VUR04_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET5340946.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHNAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19136..19942
                     /locus_tag="VUR04_001039"
     CDS             19136..19942
                     /locus_tag="VUR04_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET5340947.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            19952..21457
                     /gene="adcA"
                     /locus_tag="VUR04_001040"
     CDS             19952..21457
                     /gene="adcA"
                     /locus_tag="VUR04_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET5340948.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMEIWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEGTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22586..23359)
                     /locus_tag="VUR04_001041"
     CDS             complement(22586..23359)
                     /locus_tag="VUR04_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5340949.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23535..24938
                     /locus_tag="VUR04_001042"
     CDS             23535..24938
                     /locus_tag="VUR04_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET5340950.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25053..25691
                     /locus_tag="VUR04_001043"
     CDS             25053..25691
                     /locus_tag="VUR04_001043"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET5340951.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25703..26143
                     /locus_tag="VUR04_001044"
     CDS             25703..26143
                     /locus_tag="VUR04_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET5340952.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26136..26567
                     /locus_tag="VUR04_001045"
     CDS             26136..26567
                     /locus_tag="VUR04_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5340953.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26558..27028
                     /locus_tag="VUR04_001046"
     CDS             26558..27028
                     /locus_tag="VUR04_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5340954.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27053..27826
                     /locus_tag="VUR04_001047"
     CDS             27053..27826
                     /locus_tag="VUR04_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5340955.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27823..28623
                     /locus_tag="VUR04_001048"
     CDS             27823..28623
                     /locus_tag="VUR04_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5340956.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28682..30976
                     /locus_tag="VUR04_001049"
     CDS             28682..30976
                     /locus_tag="VUR04_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET5340957.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            30986..34102
                     /locus_tag="VUR04_001050"
     CDS             30986..34102
                     /locus_tag="VUR04_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET5340958.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVINRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34185..35951
                     /locus_tag="VUR04_001051"
     CDS             34185..35951
                     /locus_tag="VUR04_001051"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET5340959.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLADLGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36097..37248
                     /locus_tag="VUR04_001052"
     CDS             36097..37248
                     /locus_tag="VUR04_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET5340960.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTATTGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37393..38277
                     /locus_tag="VUR04_001053"
     CDS             37393..38277
                     /locus_tag="VUR04_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET5340961.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38721..38972
                     /locus_tag="VUR04_001054"
     CDS             38721..38972
                     /locus_tag="VUR04_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5340962.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWLELENKLLNLWEH"
     gene            38960..39250
                     /locus_tag="VUR04_001055"
                     /pseudo
     CDS             38960..39250
                     /locus_tag="VUR04_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        12202 a         6809 c         8565 g        11875 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaatagg ctccataata tccatagggg atttacccac tacaaatatt atagagccgt
      121 ttttttgatg aggaaagaat ggcggcattc aagagactct ttaagagagt tacgggtttt
      181 aaactattaa gccttctcca attgcaagag ggcttcaatc tctgctaggg tgctagcttg
      241 cgaaatggct ccacggagtt tggcagcgcc agatgttcca cggagatagt gaggagcgag
      301 gccgcggaat tcacgaactg cgacgttttc tcctttgagg ttaatcaatc gtttcaagtg
      361 ttcgtaggcg atcttcatct tgtcttcaaa ggtcaaatca ggtaggattt ctcctgtttc
      421 aaagtaatgg ttgatttggt tgaagaggta aggatttccc atggcagctc ggccaatcat
      481 gactgcgtca gcaccaactt cttcgatgcg ttgcttggct tcttggacag tacggatatc
      541 accgttggcg atgaatggaa tcttggttag agcttgggca accttgtaaa gggtctcaag
      601 gtctgcgtgg ccagtataca tttgttcacg ggtacggcca tgcatggcga gggcagaaac
      661 acctgcagcc tcagcagcga gggcattttc tactgcaaga gatgggtccg cccagccagt
      721 acgcattttg acagtaagtg ggatatcaag gacagactgg accttgttga tgatagagta
      781 gatcttgtca ggatccttga gccacatagc accagcttcg ttcttcacga ttttgttgac
      841 agggcagccc atgttgatat cgacgatatc ggtcttggtg ttttcttgga tgaattctgc
      901 tgcgcgtgct aggctgtctt catcgctacc aaaaagttgg atagagacag ggttttcgcc
      961 ctcatcgata tgaagcatgt gcagggtttt ttcgttgttg tattggattc ccttgtcaga
     1021 gaccatttcc attacaacga gtccagctcc gagctctttt gcgatggtac gaaaggctga
     1081 gttggtcacg ccagccatag gcgctaaaac ggtacgattg ggaatctcaa cattgccaat
     1141 cataaaaggt gtattaagat ttgtcacgaa tgagttcctc caggtccttt tcatcaaagt
     1201 tgtaagtagt ttggcagaat tgacaagtga tttctgcccc gtggtcttcc tctttcattt
     1261 cctgtaagtc tgagcttgga aggctggcaa gagcgttcat aaagcgttca tggctacagt
     1321 cacattggaa acggatttct tcttcagaaa gacgcttgta ggcttcgtcc ccgtagatag
     1381 ccttgaggag ggcttcgata tggtcgtcgc tttcgagaag agtagagata gctggcattt
     1441 cttggatgcg tttttcaaag cgagcaatct cttctttctt ggctcctggc aagacttgaa
     1501 ctaggaaacc acctgcaacc ttgaccttgt cttcctcgtc caaaaggaca ttgaggccga
     1561 ccgctgaagg cgtttgttgg ctttcagtaa ggtaaaaggc aaggtcttca ccgatttctc
     1621 cagagatgag gggagttata gagttgtaag gatttccagt accgtagtct gtgataacga
     1681 ggaattgacc atttccaaca aaaggtccga ctaggacttc accagtcgca gtctttttga
     1741 tgtcaacacc aggattttga acatagcctt tgacgttccc cttggtatca gcgacggtga
     1801 taatagcacc tagagagcta gagcccaaca ccttaactgt aagtttggta tttccttttt
     1861 cattggctgc gagaatctgg ctggcgataa gagttcgacc aagcgctaca gttgagctag
     1921 cttgggtttg atgtttttct tgagcagtgc ggacggtttc cgtgctatca aggacaaaag
     1981 cacgaaaggc tccgctttct gatatagttt taataatttt atccatagct actattttag
     2041 cataaaaatg cccaaagggg gagccgtgtg tttactgatt ttcaggataa tggaccagga
     2101 aatcagcatg aaaataaaaa gagaaacaga ttattttagc atttgtaaga tttatgctat
     2161 gcttaaggta gaaaatgaaa ggggtaacaa atgtatttag gagatttgat ggagaaagcc
     2221 gagtgtggtc aattttcaat cctttccttt ctattacaag agtctcagac gaccgtcaag
     2281 gctgtaatgg aagaaacagg attttcaaaa gcaaccctaa ccaaatatgt caccctgctc
     2341 aatgacaagg ctttggatag tggcttagag ctggctattc actcagaaga tgaaaatctg
     2401 cgtctgtcta tcggtgcagc taccaagggg agagatattc ggagcttgtt tttggagagt
     2461 gctgttaaat accagatttt ggtttatctt ctctaccacc aacagttttt agcccatcag
     2521 ctggctcaag aattggtgat tagcgaggct acgcttggtc gtcacttggc tggtttaaat
     2581 cagattttgt cagaatttga tttatccatc caaaatggac gttggcgagg tccagagcat
     2641 cagattcgct atttctattt ctgtcttttc cgaaaggtct ggtcgagtca ggaatgggaa
     2701 ggtcacatgc agaaaccaga gagaaaacag gagattgcca atttagagga aatctgcggt
     2761 gcaagtttgt ctgtggggca gaaattggac ttggttctct gggctcacat cagtcaacaa
     2821 cgtcttcggg tcaatgcttg tcagtttcaa gtcatagaag agaaaatgcg agggtatttt
     2881 gacaatattt tctaccttcg tttgctgaga aaggttccgt ccttttttgc tgggcaacat
     2941 attccactag gagttgagga tggtgagatg atgatattct tctcttttct cctatctcat
     3001 cgcattcttc ctcttcatac tatggagtat attcttggtt ttggagggca gttggcagat
     3061 ttactgacgc aattgattca agaaatgaag aaggaggaac tattggggga ttatacagag
     3121 gaccatgtca cctatgaact cagtcagctt tgtgctcaag tctatctcta taagggctat
     3181 attttacagg atcgctacaa gtaccagtta gagaatcgtc atccatattt actgatggaa
     3241 catgatttta aagagacagc agaggagatt tttcatgctc tacctacttt tcaacagggg
     3301 acagatttag ataagaagat tctctgggaa tggctccagt taatcgaata tatggctgaa
     3361 aacggtggcc agcatatgcg gattggtctg gatttgacat ctggttttct tgtcttttca
     3421 aggatggcag ccattttgaa acggtatttg gaatacaatc gttttattac cattgaagct
     3481 tatgacccta gtcggcatta tgatttgctg gttaccaata acccgattca taagaaggaa
     3541 cagcccccag tttattattt aaaaaatgac ttggatatgg aagatttggc agggattcgt
     3601 cagttattat tcacttaaaa ggcttggtta atccaggtct tttttgtgaa attcacacaa
     3661 tctcctcaca tttttttaaa aattaaaaaa agttgataaa caagaaagcg ctttattttg
     3721 tatactagta agtgtaaaga ggaaacacct caagatcttt atcaggagga cagtacatgt
     3781 cacaagaaaa atacatcatg gccattgacc agggaactac aagttctcgt gccatcattt
     3841 tcaacaaaaa aggggaaaag gttagctcga gtcaaaaaga gtttacccag attttccctc
     3901 aggcaggttg ggttgagcac aatgccaatg aaatttggaa ctctgttcag tcagttattg
     3961 cgggtgcttt catcgaaagt ggtgtcaagc caaatcaaat cgaggcaatc gggattacca
     4021 accaacgtga aacaacggtt gtctgggata agaaaacagg acttcctatc tacaatgcta
     4081 tcgtttggca gtcacgccag acagcacctt tggctgagca actaaaaagc caaggttatg
     4141 tggaaaaatt ccatgaaaag actggtttga ttattgatgc ttacttctct gctaccaagg
     4201 ttcgttggat tttggatcat gtagaaggtg ctcaagagcg agcagaaaaa ggggaattgc
     4261 tctttggtac tatcgatact tggttggttt ggaaattgac tgacggtgcg gctcacgtga
     4321 ctgactactc aaatgcagct cgtaccatgc tttataacat taaagaactc aaatgggatg
     4381 atgagatttt ggaaatcctt aacattccga aggctatact tccagaagtt cgttctaact
     4441 ccgaaatcta cggcaagaca gctccattcc atttctacgg tggagaggtg ccaatctcag
     4501 gtatggctgg ggaccaacaa gcagccctct ttggacagtt ggcttttgag ccaggtatgg
     4561 ttaagaatac ttatggaaca ggctctttca tcatcatgaa tactggggaa gagatgcagt
     4621 tgtctgaaaa caacctcttg acaaccattg gttacggaat caacggtaag gtttattatg
     4681 ccttggaagg ttctatcttc atcgcaggaa gtgctattca gtggcttcgt gacggtcttc
     4741 gcatggttga aaattcacca gaatctgaaa aatacgctcg tgattctcac aacaacgatg
     4801 aagtttatgt cgttccagcc tttacaggtc taggcgctcc atactggaac caaaatgctc
     4861 gtggttccgt ctttggtttg actcgtggaa caagcaaaga agactttatc aaggcgactt
     4921 tgcaatctat tgcttatcaa gtgcgtgata tcatcgacac catgcaagtg gatactcaga
     4981 ccgccattca agtactgaag gtggatggtg gtgcagccat gaacaacttc ctcatgcagt
     5041 tccaggcgga tattttaggc attgacattg cacgtgctaa aaacttggaa acaacagctc
     5101 taggagcggc cttcctagca ggtttgtcag tagggtactg gaaagacttg gacgagttga
     5161 aactcttgaa cgagacagga gaactctttg agccatctat gaacgaatct cgcaaggaac
     5221 aactctacaa gggctggaag aaggctgtga aagcaactca agtctttgcg gaagtagacg
     5281 actaatactg gcagaataaa gcgatttatt tagaaagtgt gtaaatatgg aattttcaaa
     5341 aaaaacacgt gaattgtcaa ttaaaaaaat gcaggaacgc accctggacc tcttgattat
     5401 cggtggagga atcacaggag ctggtgtagc cttgcaggcg gcagctagcg gtcttgagac
     5461 tggtttgatt gaaatgcaag actttgcaga aggaacatct agtcgttcaa caaaattggt
     5521 tcacggaggt cttcgctacc tcaaacaatt cgacgtagaa gtggtctcag atacggtttc
     5581 tgaacgtgca gtggttcaac aaatcgctcc acacattcca aaaccagatc caatgctctt
     5641 accagtttac gatgaagatg gagcaacctt tagcctcttc cgtcttaaag tagccatgga
     5701 cttgtacgac ctcttggcag gtgttagcaa cacaccaact gcgaacaagg ttttgagcaa
     5761 gaaagaagtc ttggaacgcc agccaaactt gaagaaggaa ggcttggtag gaggtggagt
     5821 gtatcttgac ttccgtaaca acgatgcgcg tctcgtgatt gaaaacatca aacgtgccaa
     5881 ccaagacggt gccctcattg ccaaccacgt gaaggcagaa ggcttcctct ttgacgaaag
     5941 tggcaagatt acaggtgttg tagctcgtga tctcttgaca gatcaagtat ttgaaatcaa
     6001 ggcccgtctg gttattaata caacaggtcc ttggagtgat aaagtacgta atttgtctaa
     6061 taagggaacg caattctcac aaatgcgccc aactaaggga gttcacttgg tagtggattc
     6121 aagtaaaatc aaggtttcac agccagttta cttcgacaca ggtttgggtg acggtcgtat
     6181 ggtctttgtt ctcccacgtg aaaacaagac ttactttggt acaactgata cagactacac
     6241 aggtgatttg gagcatccaa aagtaactca agaagatgta gattatctac ttggcattgt
     6301 caacaaccgc ttcccagaat ccaacatcac cattgatgat atcgaaagca gctgggcagg
     6361 tcttcgtcca ttgattgcag ggaacagtgc ctctgactat aatggtggaa ataacggtac
     6421 catcagtgat gaaagctttg acaacttgat tgcgactgtt gaatcttatc tctccaaaga
     6481 aaaaacacgt gaagatgttg agtctgctgt cagcaagctt gaaagtagca cctctgagaa
     6541 atatttggat ccatctgcag tttctcgtgg gtctagcttg gaccgtgatg acaatggtct
     6601 tttgactctt gctggcggta aaatcacaga ctaccgtaag atggctgaag gagctatgga
     6661 gcgcgtggtt gacatcctca aagcagaatt tgaccgtagc tttaaattga tcaattctaa
     6721 aacttaccct gtttcaggtg gagaattgaa cccagcaaat gtggattcag aaatcgaagc
     6781 ctttgcgcaa cttggagtat cacgtggttt ggatagcaag gaagctcact atctggcaaa
     6841 tctttacggt tcaaatgcac cgaaagtctt tgcacttgct cacagcttgg aacaagcgcc
     6901 aggactcagc ttggcagata ctttgtccct tcactatgca atgcgcaacg agttggctct
     6961 tagcccagtt gacttccttc ttcgtcgtac caaccatatg ctctttatgc gtgatagctt
     7021 ggatagcatc gttgagccag ttttggatga aatgggacga ttctatgact ggacagaaga
     7081 agaaaaagca acttaccgtg ctgatgtcga agcagctctc gctaacaacg atttagcaga
     7141 attaaaaaat taagaaaaaa taaaagaggt ggagggcagc attccttgtc gcccgtccct
     7201 tctttttaat ggagacagaa agatgatgaa tgaattattt ggagaatttc tagggacttt
     7261 aatcctgatt cttctaggaa atggtgttgt tgcaggtgtg gttcttccta aaaccaagag
     7321 caatagctca ggttggattg tgattactat gggttggggg attgcagttg cggttgcagt
     7381 ctttgtatct ggcaagctca gtccagctca tttaaaccca gctgtgacca tcggtgtggc
     7441 cttaaaaggt ggtttgcctt gggcttccgt tttgccttat atcttagccc agttcgcagg
     7501 ggccatgctg ggtcagattt tggtttggtt gcaattcaaa cctcactatg aggcagaaga
     7561 aaatgcaggc aatatcctgg caaccttcag tactggacca gccatcaagg atactgtatc
     7621 aaacttgatt agcgaaatcc ttggaacctt tgttttggtg ttgacaatct ttgctttggg
     7681 tctttacgat tttcaggcag gtatcggaac ctttgcagtg ggaactttga ttgtcggtat
     7741 cggtctatca ctaggtggga caacaggtta tgccttgaac ccagctcgtg accttggacc
     7801 tcgtatcatg cacagcatct tgccaattcc aaacaaggga gacggagact ggtcttacgc
     7861 ttggattcct gttgtaggcc ctgttatcgg agcagccttg gcagtgcttg tattctcact
     7921 tttctaatct agaaaacaat tatgttgata gagcttgggc aagagcccaa tttcagcaaa
     7981 aaatgaagta aatcttctca taataaaacg catcatatca agcacgaaaa ttccacgagg
     8041 tcaactacag tcagaaagct gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc
     8101 aagcacctgc aagcaacgtg ccgaaatagt caaattctga ttatgtcaac gaattagacc
     8161 caaaaatcgt tgatatgcta gtagaatttc acaagtcaca aggcactttg gaaactcccg
     8221 aggcgcaagc agaaatcgcc caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg
     8281 aggataaaaa acaagagctt ttgaaccgct tgaacaaata gagtttcgca agtattatgc
     8341 ttacaaatta cttgagcaat taactaaaat ataaaccctg cctttatatc taggcagggt
     8401 ttatatttta gaaattcacg taggttgtta cggtttttac atacccagta tagtttgagt
     8461 ttctatagta ttcagtgata aacttccatt ttctttgagc aacatggata taagtacttg
     8521 ttatgtagta tggatatggg ctttgtgaat ccaagtaaga ctgataagct tgtataccaa
     8581 aatatgctcc accaattatt gcaccccatg gaccccccaa taaagcacct atcctaccaa
     8641 tcatataact gattccagca ccagtcatga agttagcgaa tgtgttagct tgtttattcc
     8701 catgtattgt gttgacgtaa tttcaaacat taggatcgta tgatctaaaa gatatattta
     8761 ggtcgatttc attcttttga taagccatat aaaatgcccc attgatatag acgccgtcag
     8821 cacgtcgttc aatagtgtct acacttccat ctggattgac aacctcaaga acttcatcgc
     8881 ttaaaatatt tacttgcgta tctccgaacc gcactgatga gccattctca aactgagcct
     8941 caccagatac aactttagag tttgccgata agctatcatc agcaaaaaca acaagcgacg
     9001 gggaaatgct agacatacag aaaacagaca taactagcaa acacatgcat ttaaacatct
     9061 tagacataac ggaaactcct ttgtattttt gatttttttc aacttttatt atacaataaa
     9121 accaaataaa aagaaagcgg taacaatatg cttaatgcga aaatttttta tatattttta
     9181 tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga aaagaggtct cgaaatgggt
     9241 tatttagaca cagaagctat tatcctcgca gttttttcat ttgcttttta caacctatgt
     9301 tcattcgctt gggtctgctc tacaataaaa aacaataaaa aataaataga cgtattttca
     9361 aaaaaaaaaa aaaatgcata tttatcttag caaaacgacg atttaaatcg tcgttttttt
     9421 gtagtacgac gggcatgtcg tatatctgag gtgtaagtcc tcggtgggca cctgctaccg
     9481 gtgaacccaa tagcgattcc caagcctgac tatcgtgagg tagcggatta aaacggtctg
     9541 gggatagacc gttttaagtc tgacgcagga aataagaatc gtcagaggaa gggatagcga
     9601 aatcgtggct ctacgaacag gaacgtgata gtaaggcgta tatagcggat aaggaggctt
     9661 caaactctaa agtccaaaaa ggtagtcgta acctatatgt gtaaatcacg agagtaattg
     9721 aattcggact aaggtctatg tgaaaaagat aaatcttcct agagtctaaa gactctgcgt
     9781 cagatttcct attttcattg taacctttta acgtcctcat atcttgtata aacgaggaaa
     9841 gatgtacggc ttatcccgtg aggtctcatg agcgccgaaa gcgtagtaac aacgaatcat
     9901 gagaagtcag ccgagcccat agtagtgagg aaacttccgt aatggaagtg gagcgaaggg
     9961 gtgaatactc aaacagtctg gggagagact gtttgaggtc tgtcgctaga aagagaaaac
    10021 gacagattga agtaatccta cttcacttgt gtctgtaaaa cgagaggtct gatagaactg
    10081 gagtctgtca cgtattgact agatgaaggc tcaccaatat aagatgtccc tcaggcacca
    10141 aaacaagaaa ggaatacgca catgtcaaaa ttgctagata agatattatc acgcgaaaat
    10201 atgctggaag cctacaatca agtaaaatcc aataaaggct cagctgggat tgatggaatg
    10261 actatcgaag agatggataa ttatctcaga caaaactggc gcttgactaa ggaactgata
    10321 aaacagagaa aatataagcc tcaaccagtt cttagagttg agatacctaa accagacgga
    10381 ggtatccgtc aactaggaat tccaacagtt atggatagaa tgattcaaca ggccattgtc
    10441 taagtcatga gccccatttg tgaaccccat ttctcagata cgagttatgg tttcagacca
    10501 aataggtcat gtgaaaaagc catcatgaag ctcttagaat acttaaatga cggctatgag
    10561 tggatagtgg atatagacct agagaaattt ttcgatacag ttcctcaaga tagattgatg
    10621 tccttagtac ataacattat cgaagacgga gatacggaat ccttgattcg taagtatctt
    10681 cattcaggtg ttatcattaa tggtcaacgt tataaaacac tagttggtac accacaggga
    10741 ggaaatttat ctcctctctt atccaatatc atgcttaatg aattggacaa ggaattagaa
    10801 aagaggggac ttcgatttgt gcgctacgca gatgattgtg tgattacggt cgtaagcgag
    10861 gcagccgcta agcgtatgat gtattcagtc agtcgtttta ttgaaaaacg gctaggtttg
    10921 aaagtaaaca tgaccaagac taagattacc agaccaagag agttgaaata tctaggtttt
    10981 gggttctgga aatcatcaga tggttggaaa agtcgtccac atcaagatag tgttcggaga
    11041 tttaagctta aattgaagaa actaacacag aggaaatgga gtatagacct aacaagacgt
    11101 attgagcaac tgaatttgtc tattcgagga tggataaact atttctcatt gggaaatatg
    11161 aaaagtatag tcgccagcat agatgagcgc ttgcgtactc gcctacgagt gattatctgg
    11221 aagcaatgga agaagaaatc gagacgatta tggggattgc ttaagttagg agttcctaaa
    11281 tggatagcag ataaggtatc tggctggggc gaccattatc aattagtagc tcagaagtcg
    11341 gtacttaaac gtgctatatc aaaaccagtc ctggaaaaac gtggactggt ttcgtgtttg
    11401 gattattacc ttgaacgaca tgcgttaaaa gttagttgaa ccgccgtatg ccgaacggca
    11461 cgtacggtgg tgtgagaggg gctagagatt atcccctact cgattaactc ccctgaaatt
    11521 tattttaatt atgcaaattt cacgtatttt tgatgctgag acgacgatcc tgggaacttt
    11581 tcagatattt ttttgactat ctaaatctat cattagaaaa gcttagagcg ccaaaggatt
    11641 tgagcgtttt tctgattttt aagacttttt ccagtctctt tttcgattga agatgtaatt
    11701 attctactaa ctaactaact tcttagtact agccaacaac gataatcata attcctccta
    11761 aaattaggaa taatagaggc aatagttttt gttttttcat gtaaaaaacc tcacttttgt
    11821 tttctgctat tttatgctaa aatattaaaa atcaaattta attctaaagt ttgtaactaa
    11881 agggggagcg ctacatgtct aattcatttg tcaagttgtt agtctctcaa ttatttgcaa
    11941 atttagcaga tattttcttt agagtaacaa tcattgctaa catatacatt atttcaaaat
    12001 cagtaattgc cacatcacta gttcctatct taataggaat atcctctttt gttgcgagtc
    12061 ttttagttcc gttggttact aaaaggttag cgctaaatag ggttttatct ttatctcaat
    12121 ttggaaagac tatattattg gcgatactgg taggaatgtt taccgtaatg caatccgtag
    12181 cgcctttggt gacctatcta tttgttgttg caatttccat actagatggt tttgcagcac
    12241 ccgtttccta tgctattgtg ccacgctatg cgaccgattt gggtaaggct aattcagcct
    12301 tatcaatgac tggtgaagct gttcaattga taggttgggg attaggtgga ctcttgtttg
    12361 caacaattgg tctgttacct accacgttta tcattttagt cttgtatatc atttctagct
    12421 ttctgatgtt atttcttcct aacgctgaag tggaggtgtt agagtcagaa actaatcttg
    12481 aaattttact caaaggttgg aagttagttg ctagaaatcc tagattaaga ctttttgtat
    12541 cagcaaattt attggaaatt ttttcaaata cgatttgggt ttcttccatt atacttgttt
    12601 ttgtaacgga gttattaaat aaaacggaaa gttactgggg atattctaat acagcatact
    12661 ctattggtat tataattagt ggcttaattg cttttaggct atctgaaaag ttccttgctg
    12721 ctaaatggga aagtattctt tttcctcttg tagctatggc aatagtgaca ctgactattc
    12781 tatattttcc aaacgcacag atgtttttat tattttcagc tttagttggt atgttatcgc
    12841 aactaaaaga agttcctgaa agtgtatttc ttcaggaaac agtagaggaa aatcatttag
    12901 ttaatgtcta ttccgttctt gaagtgattt ctacattagc attttcagta tttgttttgc
    12961 taatgagcta tattactgag agttttggta ttagcatcag tttttggcta tcagccattt
    13021 gtctgatgat agaagctatt ttaatttata tcagacgaga ttattttaaa tgagagagtg
    13081 gttaaaaagt ctttaaaaat cagaaaagcg catagtatca ggtgttgaaa aaacttgata
    13141 ttgtgtgttt tattatggga agatttactt cattgtctcc tgaaatggag ttttgaagca
    13201 ggatcactct atttgaaaat atacatagaa aaactgtata atccttaaaa taagctgaaa
    13261 tctattggaa acatacggta aacaattgaa aagatactat ataaagtggt acaatggtag
    13321 aaaaataagc tagtaagaat cactcttatt ttagcgaaaa attacagaaa tgaatggttt
    13381 ttcttgatga aacagagaaa agaattgtac ctctttcttg gtcggacagc cttgtatttt
    13441 cttatctttc tagggctgct ttacttcttt agctatcttg gtcagggtca aggaagcttt
    13501 atctataatg aattttaact tgaaggagaa tccctattgt gtcaaataaa ccaatagcag
    13561 atatgattga aaccattgag cattttgctc agacacagcc tagctatcct gtctataatg
    13621 ttttggggca gagacacact tatggcgatt taaaggctga ttcggatagt ttggctgcag
    13681 tcattgacca actaggcttg cctgagaagt ctcctgtggt tgtttttggt ggccaagaat
    13741 atgaaatgtt ggcaaccttt gtagcgctga ctaagtcagg tcatgcctac attccaattg
    13801 atagccattc ggccttggag cgagtttcag ctattttaga agtagcagag ccaagcttga
    13861 ttattgccat ttcagccttt cccttggagc aggtttctac accaatgata aatctagctc
    13921 aggttcaaga agcctttgcc caagggaaca actatgaaat cacgcatcca gtcaagggag
    13981 atgataatta ctacattatc tttacttctg gtacgactgg taagcctaag ggagtgcaga
    14041 tttcacatga taatctcctc agctttacaa actggatgat tacggataag gaatttgcga
    14101 caccgagtcg tccgcaaatg ctggcacagc caccttattc ttttgacttg tctgtcatgt
    14161 attgggcacc gaccttggca cttggtggta cgcttttcac tcttccttca gtcatcactc
    14221 aggactttaa gcaactcttt gcggctatct tttcattgcc aatcgctatc tggacatcaa
    14281 caccatcctt tgcagatatg gccatgttgt ctgaatactt caacagtgag aaaatgcctg
    14341 gaatcacgca tttctacttt gatggtgaag aattgacggt caaaacagct caaaaactgc
    14401 gcgagcgttt cccaaatgcc cgtatcatca atgcttacgg cccaacagaa gcgacagtag
    14461 ctctgtcagc agttgccgtg acagacgaga tgttagcgac tctcaaacgc ctaccaatcg
    14521 gctataccaa ggctgattct ccaaccttta tcattgacga ggaaggaaat aaactgccaa
    14581 atggtgagca gggagaaatc attgtttctg ggccagctgt ttcaaaaggt tatatgaaca
    14641 atcctgaaaa aacagcagaa gccttctttg agtttgaaga tctgccagcc tatcacacag
    14701 gcgatgtggg aaccatgaca gatgagggct tgcttctcta cggcggacgc atggacttcc
    14761 agattaagtt taacggttac cgcattgagt tagaagatgt ctctcaaaac ctcaacaagt
    14821 ctcgctttat cgaatctgct gtcgcagtac cgcgctataa caaggaccac aaggtacaaa
    14881 atctattggc ttatgtcatc ttaaaagacg gtgttcgtga gcagtttgag cgagatatcg
    14941 atattaccaa ggccatcaag gaagacctga cagacatcat gatgtcctat atgatgccat
    15001 ctaaattcct ttaccgagac agtttgccac taactccaaa tggaaagatt gacatcaaag
    15061 gattgattaa cgaggtgaat aagagatgat ggagtttttt caacagcttc ctcatttaga
    15121 gccatatggc aatcctcagt attttgttta tgtgattgct gcaaccttgc ccatctttat
    15181 aggtctcttt ttcaagaaac gctttgcctg gtatgaagtg ttggtaagtc tcttctttat
    15241 tgtcaccatg ttggtgggtg gaaagaccaa tcaactagct gccttgggta tttacctttg
    15301 ctgggaaata ttgctcctgc ttttctacaa gcattatcga aaaagcaagg atggcaagtg
    15361 ggtcttctac ttagttagtt ttctgtccct acttccgatt atctttgtca aggtgcaacc
    15421 agctatcaat ggaacgcagt ctttgcttgg gttcttggga atttcttacc ttacctttcg
    15481 ttcggttgga attgtcatcg agctgagaga tggagtgatt aaggatttta ccctctggga
    15541 attcctccgt ttccttctct tcatgccaac tttctcgagt ggtccaatcg atcgctttaa
    15601 gcgatttaat gaaaattatc aggctattcc tgagcgagat gagttgatgg atatgctgga
    15661 tgaatctgtc cgctatatca tgtggggctt tttgtataag tttatcctag ctcatgtttt
    15721 aggagagacc ttactacctc ctctgaagaa tttagccttg cagtcaggtg gcttctttaa
    15781 tctctatgcc ttggcagtta tgtatacttt tggtctggag ctcttctttg actttgcagg
    15841 ttattctatg tttgctttgg ccatctcaaa cttgatggga atccgtagcc ctatcaactt
    15901 taacaagccc tttttatcaa gggatttaaa ggagttttgg aatcgctggc atatgagtct
    15961 gtccttctgg ttccgtgact ttgtctttat gcgaatggtg atggtgttaa ccagaaagaa
    16021 agtctttaaa aatcgtaatg taacctcaag catggcctac attgtaaata tgctgattat
    16081 gggattttgg catggtgtga cctggtacta tatcgcctat ggactctttc atggactagg
    16141 cttggtcatc aatgatgcct gggttcgcaa gaaaaaaacg ctcaataagg aacggaaaaa
    16201 agcagggaag gctgccctac ctgagaatcg ctggattcag ttgcttggca tggttgtcac
    16261 tttccatgtt gtcatgttgt cattcttaat cttttctgga ttcttgaata atctatggtt
    16321 taaaaaataa aaggaaataa aatatggata tcaaatcaga agttattgaa attattgatg
    16381 agttgtttat ggaagatgtt tctgacatga tggatgaaga tctttttgat gcaggtgtct
    16441 tggatagtat gggaacggtt gagttgattg tggagattga gaaccgtttt gacattcgtg
    16501 tccctgtaac agagtttggt cgtgacgact ggaatacagc taataaaatc atagctggta
    16561 ttgtggagct acaaaatgct taaacgctta tggatgatct tcggaccggt cttgatcgct
    16621 ggtttgttgg tttttctgct cattttcttt tatcctactg agatgcatca taatctagga
    16681 gctgaaaagc gttcagcggt ggctactact atcgatagct ttaaggagcg aagtcaaaaa
    16741 gtcagagcac tatctgatcc aaatgtgcgt tttgttccct tctttggctc tagtgaatgg
    16801 cttcgttttg acggtgctca tcctgcggta ttagctgaga aatacaatcg ttcctaccgt
    16861 ccttatcttt taggacaggg gggagctgca tcgcttaacc aatattttgg aatgcaacag
    16921 atgttaccac agctggagaa taaacaagtt gtgtatgtta tctcacctca gtggttcagt
    16981 aaaaatggct atgatccagc agccttccag cagtatttta atggagatca gttgactagt
    17041 tttctgaaaa atcaatctgg ggatcaggct agtcaatatg cagcgactcg cttactgcaa
    17101 cagttcccaa acgtagctat gaaggacctg gttcagaagt tggcaagtaa agaagaattg
    17161 tcgacagcag acaatgaaat gattgaatta ttggctcgtt ttaatgaacg ccaagcctcc
    17221 ttttttggtc agttttcggt tagaggctat gttaactacg ataagcatgt agctaagtat
    17281 ttaaaaatct tgccagacca gttttcttat caagcaatag aagatgttgt caaagcagat
    17341 gctgaaaaaa atacttccaa taatgagatg ggaatggaaa attatttcta taatgagcag
    17401 atcaagaagg atttgaagaa attaaaggat tctcagaaaa gctttaccta tctcaagtcg
    17461 ccagagtata atgacttgca gttggtttta acacagtttt ctaaatctaa ggtaaacccg
    17521 atttttatca ttccacctgt taataaaaaa tggatggact atgctggtct acgagaggat
    17581 atgtaccaac aaacggtgca gaagattcgc taccagttag aaagtcaagg ttttaccaat
    17641 atagcagatt tttctaagga cggcggggag cctttcttta tgaaggacac cattcacctt
    17701 ggttggttgg gttggttggc ttttgacaag gcagttgatc ctttcctatc caatcccaca
    17761 ccagctccga cttaccatct gaatgagcgc tttttcagca aagattgggc gacttatgat
    17821 ggagatgtca aagaatttca atagataata taatatagaa gagttcaaga atgaaactag
    17881 ttttcacgtt ttttcttgac tctttttttg cttgtgatat aattaactgg taaacaaaat
    17941 gtcaaagaat agtatttttc tcttaaaaaa gagaagtcta aaaggaaagg agtcagatat
    18001 gagacagcta gcaaaggata tcaatgcttt tttgaatgag gtgattttgc aggcggaaaa
    18061 tcagcatgaa atcctaatag gtcattgcac tagcgaggtg gccctgacca atactcagga
    18121 gcatatcctt atgctcttgt cagaggaatc tttaacaaat tcagaattgg cccgtcgtct
    18181 caatgtcagt caggcggcag ttaccaaggc cattaagtct ttggtcaagg aagggatgtt
    18241 ggaaacatct aaagattcta aagatgcgcg tgtgattttt tatcagttga ctgacttggc
    18301 tcgtccaatc gctgaggagc accaccatca ccatgagcat acacttttaa cctatgaaca
    18361 agtggcgact cagtttactc caaatgaaca aaaagtgatt cagcggtttt tgactgcttt
    18421 agtaggagaa atcaaataat gagatatatt acggtagagg atttgtcctt ctattatgat
    18481 aaggagcctg ttcttgaaca tatcaattat agtgttgata gtggggaatt tgttaccttg
    18541 actggggaaa atggagcggc taagacgacg ctcatcaagg ctagtcttgg aattctgcaa
    18601 ccacgcattg gaaaggtggc tatttcaaag acaaatacgc aaggtaagaa attgagaata
    18661 gcctatcttc ctcaacaaat tgccagtttt aatgctggtt ttccaagtac ggtctatgaa
    18721 tttgtcaagt cgggtcgcta tccgagaaaa ggctggttcc gtcgtttgaa tgctcatgat
    18781 gaggagcata tcaaggccag tctggactca gttggcatgt gggaacatcg agacaaacgc
    18841 ttggggtctc tatctggggg acaaaagcag cgagcggtga ttgcgcgtat gtttgcttct
    18901 gaccctgatg tgtttatcct agacgagccg acaacgggga tggatgcagg aagtaaaaat
    18961 gaattttacg aactcatgca ccacaacgcc catcatcatg gcaaggctgt tttgatgatt
    19021 acccatgacc ctgaagaagt taaggattat gcggatcgca atattcatct agtccgtaac
    19081 caagactcgc catggcgttg tttcaatgtt catgagaatg gccaggaggt gggccatgct
    19141 tagtttatta tcttacgact ttatacaacg cgcctttttg gcggttattg ctatgagtct
    19201 tttctcaccg gtattgggaa ccttcctcat cttgcgtcgt cagagtttga tgagtgatac
    19261 ccttagccac gtctcacttt caggtgtagc ctttggtctg gttttgggga tttctccaac
    19321 tgtttctact attgccattg tcttgattgc ggcggtcttt ctggagtatc tccgtacggt
    19381 ttacaagagc tttatggaaa tcgggacagc tatcctcatg tcaacaggtc tggctgtttc
    19441 tctgattgtc atgagcaagg gtaaaagctc gagttcaatg agtttggacc aatatctctt
    19501 tggttcgatc gtgactatca gtgaagaaca ggtcatttcc ctctttgtca ttgcggcggt
    19561 tgttttgatt ttgacctttc tctttcttcg tcctatgtat atcttaactt ttgacgaaga
    19621 tacggccttt gtggatggct tgccagttcg taccatgtcc attcttttta acatggtgac
    19681 aggggtggct attgccctta tgattcctgc agcaggagct cttctggtat cgaccattat
    19741 ggtcttgcca gctagtattg ccctgcgtct ggggaaaaac tttaaatcgg ttatgctgct
    19801 tgccagtgcg attggctttt tgggaatggt agcaggactt tacatttcct actatgcaga
    19861 aacacctgca agtgcaagta ttaccattat ttttgtaact gtctttatac taatcagttt
    19921 agtaagacgt tttatcaaat aggagacgaa cgtgaaaaaa attagcttat tactagccag
    19981 tctatgtgcc ttgtttttag tggcttgttc caatcaaaaa caggcagatg gtaaactcaa
    20041 tatcgtgaca accttttacc ctgtctatga atttaccaag caagtcgcag gagatacggc
    20101 taatgtagaa ctcctaatcg gtgctgggac agaacctcat gaatacgaac catctgccaa
    20161 ggcagttgcc aaaatccaag atgcagatac cttcgtttat gaaaatgaaa acatggaaat
    20221 atgggtacct aaattgctag ataccttgga taagaaaaaa gtgaaaacca tcaaggcgac
    20281 aggcgatatg ttgctcttgc caggtggcaa ggaagaagag ggagaccatg accatggaga
    20341 agaaggtcat caccatgagt ttgaccccca tgtttggtta tcaccagttc gtgccattaa
    20401 actagtagag cacatccgcg acagcttgtc agcagattat cctgataaaa aagagacctt
    20461 tgagaagaat gcagctgcct atatcgaaaa attgcaagcc ttggataagg cttacgcaga
    20521 aggcttgtct caagcaaaac aaaagagctt tgtgactcaa cacgcagcct ttaactatct
    20581 tgccttggac tatggactca aacaagtcgc aatctcagga ctttctccag atgcagagcc
    20641 atcagctgct cgcttggcag aattgacaga gtatgtcaag aaaaataaaa tcgcctatat
    20701 ctattttgaa gaaaatgcct cacaagccct tgctaacaca ctttcaaaag aagcaggtgt
    20761 caaaactgat gtcctcaatc ctttagaaag tctgacagaa gaggacacca aggctggaga
    20821 aaactacatt tccgtgatgg agaaaaacct caaggctttg aaacaaacaa cagaccaaga
    20881 aggcccagca atcgaacctg aaaaggcaga gggtaccaag acagtccaaa atggttactt
    20941 cgaggatgca gctgttaagg accgcacctt gagtgattat gcaggtaact ggcaatcagt
    21001 ttatcctttc cttgaagacg gcacgtttga ccaagtcttt gactacaagg ctaagttgac
    21061 tggtaagatg acccaggctg agtacaaggc ttactataca aaaggctatc agacagatgt
    21121 gactaagatt aacattactg ataatactat ggaatttgtt caaggtggac aaagcaagaa
    21181 atacacttac aagtatgtcg gtaagaaaat tttgacttac aagaaaggca atcgtggcgt
    21241 gcgtttcctc tttgaagcca cagatgctga cgctggacaa ttcaagtatg ttcagtttag
    21301 tgaccacaat atcgccccag ttaaggcaga acatttccat atcttctttg gaggcacaag
    21361 ccaagaagcc ctctttgaag aaatggacaa ctggccaacc tactacccag ataacctatc
    21421 tggccaagaa atcgcccaag aaatgttggc gcattgatga gaaatcgact agttcataag
    21481 agctagtcgg ttttttgata ctagatggct aacttcatta tagacctttc agaactaagg
    21541 gaacctgaaa aaataaataa aactcttgaa atatctggac ttatatgcta gaatgtagtt
    21601 agtgtataag gttcattaga acaccaaagc ccctaactag tgccatagtt aagggctttt
    21661 ttgacgtatc ttagcgattt aacgggtgtt tataggctag tcagtcggtc tacttcttac
    21721 catctagcca tttgcagacg aaatacaaga taattccagc tataacatct gttataatag
    21781 taagagcaag ctctggtata aggctcatta gtttcacctc ctctcacgaa cccataggaa
    21841 cgtaatcggt aaccgatgac aaaaatagta taccacacta aatttagatc atcaacctca
    21901 cttaatgctt gaactattgt agattatatg ctaaaatgta gttaattgat aaggttcatt
    21961 agaacaccaa agcccctaac tatggccgta gttaagggct tttttgacgt atcttagcga
    22021 tttaacgggt gtttataggc tagtcagtcg gtctactcct tactatctag ccatctgcag
    22081 acgaaataca agataattcc agctataaca tccgctataa tagtaagagc gagctctatg
    22141 ataaggctca ttagtttcac ctcctctcac gaacccatag gaacgtaatc ggtaaccgat
    22201 gacaaaaata gtataccaca atacatttag atcatcaagg tcacttaatt cttgaaatat
    22261 agggtctagg cgacaaagtc tttaaaatca gaaaaacgca taatatcagg tgtgcaaaaa
    22321 cttgatacta tgcgttttat tgtgggaagg tttactccat tttctcctga aattgagttt
    22381 ttgtccagcc tctgttttta gggttgctaa gaaaataatg tcatgtggtg aatatttgta
    22441 aatcagtcag cagacagaac gaatactctt cgaaaatctc ttcacatcat gtcagcttcg
    22501 tcttgccgtg tccatggggg acttgacttc atcagttttc aaatctgtac tgtgagcaag
    22561 ttgagactag cttcctattt gatttttatt gaatatcaga aacccattct ccatcaaata
    22621 attcgactgc gtctaataat ttttgatctg gcacggtgtc tgaaataaag gttgtgtatt
    22681 tggatagggg attaatttta aaaaatccag tcttgtaaaa tttagaacta tcaatcagta
    22741 agatggtttc atgggctttg tcaataatat tcttttttga aatagcttgg ctgagagaag
    22801 cttcataaac atattggtca tcaatacctc ttgctgaaca aaatgctaaa tcgatattaa
    22861 aatgatctaa taaagaattt tccttatcat agttgaccac ggaacaggat tgatgtttga
    22921 cctcgccaga tgtgataaag attttggagc tatctttaac agtttcagat agggtttgtg
    22981 cagtatgtaa accatttgta aaaataatca aattatcaag ttcagaaaga tagggacaaa
    23041 gttcgtagac agtcgtacta gaatctagat agatacacat accagaccga ataaagtctt
    23101 tagcgagact agcgattagt cttttttgcc tagtactttc tccttcccgt atttgatgag
    23161 aaagttcaat tgtgttcata gaggacaggg tcacgtatcc gtgctttctt ttgataagac
    23221 cttgattttc taagaaaatt aaatcacgac gtaaggtact tgtgctggag aaagtgattt
    23281 ctgccagctc ttttacggca attctttttt tctttttgat aatttcaatc aattcaagta
    23341 cacgttcatc ttttatcata agctcctcct aatttatcat ttcaactata ttatagcaca
    23401 aattggagga atttgaatta tttttatgaa tattgggtta acatttgaac attattcaag
    23461 taagcgttca catattgaaa aaataaaacg tggggattat aataaagtta atcaaggacg
    23521 aagagagaag aaaaatggaa gcggttttag caatagattt aggtgcgact tctggaagag
    23581 caatcgttgg ttacctttct gaaaataaac tagtaatgga agaaataaat cgcttttcta
    23641 atctacctat tagagtaaaa gggcatttat cttgggatat tgactttcta ctagctaaaa
    23701 ttcttgaaag tatccgcttg gctaatacta gttacaagat tttatctatc ggtattgaca
    23761 catggggagt tgattttgga ctgattgata atgaaggtaa gctgttatca caacctgttc
    23821 attatcgtga tgaaagaaca aagggagtgt taaaggaaat atctgaaatg actgaattag
    23881 aaaaactgta ttcagagaca ggaaatcaga ttatggagat aaataccttg tttcaactct
    23941 ttaaggcacg tcaagaatct cctgactctt tctataagac caataagatt cttttaatgc
    24001 cagatttgtt taattatctc ttgacaggta agtttgctac agaaaaaagc attgcttcaa
    24061 caactcaatt atttgatcct aggagtcaaa attggaatca aaatatctta aaactatttg
    24121 aattggattc atctttactt cctgaaattg tttcagaggg aaatgttctt ggaaggataa
    24181 aaaaggagta tggtttaggc gatattcctg ttgtgaatgt ttgtagtcat gatacagcaa
    24241 gtgcgattgt ctcagtacct aagacagaag gtagtttatt tatttcatca ggtacttggt
    24301 ctttggttgg agtggaactt acttcaccga ttcttactac cgaatccttc agttatggat
    24361 ttacaaatga agtcggtaaa gatggagtga ttacatttct gaagaattgt acagggttgt
    24421 ggatcataga ggaactaaga cgttcgtttg aacgaagagg gaaagcctat tcttttgatg
    24481 atattaggac aatggtggag aaagaaaaag aaaatcttcc tctgattgat actgaatcaa
    24541 ctgaatttgc aacagaatct gatatgcaca agactttgac agaatatcta gcttatcatc
    24601 atgaaactag agagtggaca gatggacaac tatttaagat tgtttatgaa agcctagctg
    24661 aaacgtatag gaaagcgata gagttactag aagaactaac tcataaggtt tataagagga
    24721 tatatgtgat tggaggaggt gctagagcca gttattttaa ccaaatgatt gctgatagaa
    24781 ctggtaaaga ggttcttaca ggtttgactg agggtacagc tgtggggaat attgttgtgc
    24841 agctcatagc tatgggacaa ttaaaaggga tggaagaagc tcaccatgtt attgaggagt
    24901 tcctacaatt agagagttat tactcccaaa agaattaaaa agattgagag tttgtaaatt
    24961 tgcctccctc ccccttctta agttttgtac aagaaggggg gataattggt gaattgaaaa
    25021 atatttagtg ttttgatatg aggaggacaa gaatgtcaga tgtaaaacaa gaattaatta
    25081 agtatggcaa gaagctagta gaaacagatt tgacgaaagg aacaggtggg aatctcagtg
    25141 ttttcgatcg tgaaaaacaa ttgatggcaa ttaccccgtc gggtattgat ttctttgaaa
    25201 tcaaagaatc cgatattgta gtgatggata ttaatggaaa tgttgtagag ggagaacgct
    25261 tgccatctag cgaatggtat atgcatttga ttcaatatca aactcgtgat gatatcgatg
    25321 caattatcca tgctcataca acttatgcaa cagtattagc ttgtctcaga gaaccacttc
    25381 cggctagtca ttatatgatt gcagtggcag ggaaagatgt tcgggtagct gagtatgcaa
    25441 catatggtac gaaagaattg gctgtgaatg cagctaaagc aatggaaggt cgtagagcag
    25501 ttttactagc gaatcatgga attttagcag gtgcacaaaa tttattgaat gcatttaata
    25561 ttgttgaaga agttgaatat tgtgcaaaaa tttattgttt agctaagaat tttggagagc
    25621 cagtagttct tcctgatgag gagatggatt taatggcaga aaaatttaaa acatacggtc
    25681 agagaaaata gggaggatat taatgttaaa acatataccg aaaaatattt ctccagattt
    25741 attgaagact ttaatggaaa tgggacatgg agatgaaata gtattagctg acgcgaatta
    25801 tccttctgcc tcatgtgcaa ataagctaat tcgttgtgat ggcgtaaata ttccagaatt
    25861 attagattcc attctgtatt taatgccatt agatagttac gtcgatagtt caattcagtt
    25921 tatgaacgtt gtttcgggtg atgatattcc taagatatgg ggtacctata gacagatgat
    25981 tgaaggtcat ggtacagatc ttaaaacgat tacttatctt agaagagaag acttttatga
    26041 acgtagtaag aaagcttatg ctattgttgc tacaggagaa acttcacttt atgctaatat
    26101 tatccttaag aaaggagtag ttgttgaaag agaaaatgtt taatagagga attttagttg
    26161 ccagtcatgg taattttgct agcggagctc tcatgaccgc agaaatgttt gttggtgaga
    26221 caacaaatga tagagttagg acattaggtt tgatgcctgg agagaatatt gtagagtttg
    26281 agcattattt taaaaatcaa gtggatgaac tgttagactc aaatcaagag gttatcgttt
    26341 tgactgactt gattggagga agtcctaata atgtggcttt gtcacggttt ttaaatttgg
    26401 attcagttga tattgtaaca gggtttaata tccctctcct agtggaatta atatcaagtt
    26461 atgattcaaa aatcaattta gaagaaattg ttcacaatgc tcaaaatagt ttgtttaatg
    26521 ttaaacaaca acttaacgta gaggaggaag aagatttatg tctatagagt ttgttcgtat
    26581 tgatgaccgt ctggtacatg gtcaagttgt cactacgtgg ctaaaaaagt atgatattga
    26641 gcaagttatc attgttaatg atcgcatctc agaagataaa acacgacaat ctattttaaa
    26701 gatttctgca ccggtaggtt taaaaattgt tttctttagt gtaaaacggt ttgtggaagt
    26761 tttaaactct gtgccaataa aaaagagaac aatgctgata tatacaaatc caaaagatgt
    26821 gtatgattct attgaaggaa atttaaaatt ggagtacctc aatgtaggac agatgagtaa
    26881 aacggaggaa aatgaaaagg taacgggagg tgtagctcta ggtgaagaag acaaatatta
    26941 ttttaagaaa atagttgata agggaacgag agttgaaatt caaatggttc ctaatgataa
    27001 agttacaatg ttggaaaaat ttttataaaa ataatttaag gaggtacagt atatgctatt
    27061 cacacaagca ttactggtga cattagttgg gattattgcc actattgact ataatggacc
    27121 gttatttatg attcaccgtc cgttagttac aagtgcaatg gttggcttag tattaggaga
    27181 tttcacccaa ggtgttctta ttggttcagc tcttgaatta acttggctcg gtgtaacagg
    27241 tattggaggt tatactccac cagatactat ttcaggtgcg attattggta ctgcatttgg
    27301 tattttatct ggtcaaggag aaactgctgg tatcgctata gcagttccaa ttgcagttgc
    27361 tacccaacag ttggatgttc ttgcaaaaac tttagatgtt tattttgtga aaaaagctga
    27421 taatgatgct aaaaacggag attattcaaa gatcggtttt tatcattatt caagtttggt
    27481 tttaatcacg ttatttaaaa ttgtaccaat tttcctagct attatgcttg gaggggaata
    27541 tgtggcagac ttgtttgcta aggttccacc aatcgttatg cagggactta actctgcagg
    27601 tgctttacta ccttcaattg gttttggtat gcttttaaat atgatgctca agaaaaatat
    27661 gtgggtattc ttgttgattg gattcatttg ttctgtgtat ggaggaatgt caaccattgg
    27721 gatctcacta gttggtattg cggtagcata cttctacgat atgattggaa gcaaaccaca
    27781 agaaacaact tcaagtagtg atgttgagga ggatcttgat ctatgatgaa taataaagta
    27841 actaaagttg aacttaaaaa agttttcaaa cgaagtttta tgtatggttc ttcatggaac
    27901 tatgagagaa tgcagaacct aggttttcta tatacaattc ttccagtatt gaaaaaacta
    27961 tacccagaca aagattcagc ttctcctgca atgaaacgtc accttgagtt tttcaatact
    28021 catcaaacag cggcaccatt tattcttgga gttacttccg ctatggaaga acaagaagga
    28081 aatgaaggtg cagcttcaat tactggtatt aaagttggct tgatggggcc actggctggt
    28141 ctaggagata gtttgttctg gctgacacta gttcctatct gttttagtat tggtgcgtct
    28201 tattctaaag acggcggtgc tttaggtatc tttatcgcct taatattgtt taatattatt
    28261 aatattcctg ttaaatattt cggtttgaaa tatgggtata ctaagggttc tagtcttatc
    28321 caagaaaata atacaaaagg aacattgaat cgcgttacga gtatggcgac agcattaggg
    28381 ctagtactag tgggtggttt gattccatca atggttggta ttaattttgg attagaattt
    28441 aagcaggggg aacttgttat ttctgttcaa gaaatgatta caaaattaat tccaggattt
    28501 atccctatgg ctttgacttt attaatgtgt aaattaatta gaaaaggaaa gaatccggtt
    28561 gtactaatct ttagtgttat ggctattgga gttatcctag ttgttttagg aattttgaag
    28621 tagtagaaag tgtggaggtg gtatttggga tatcacctcc attttggaag agaggtaaag
    28681 agtgaaatta tggtataaga aagctgcctc aaattggaat gaagccttgc cgattgggaa
    28741 cggtcattta ggtggtatga tttatggttc agctacaaaa gaatgtattc aactaaacga
    28801 tgagactatt tggtatagag gaaagtcaga tagaaataat ccagactcac tattgcatct
    28861 taaaaaaatt cgggaatatc ttttagatgg agaaattcag aaagccgaag aattgataaa
    28921 gttaacaatg tttgctaccc caagagatca aagccactat gaattacttg gggaacttta
    28981 cattgagcat atagatattc agtcttgtgc tctttcattg tatgaaagag agctagattt
    29041 agatacagct atttctaatg ttgtgtttga gcctaatagt tgtaatttac aaataaaaag
    29101 agaatatttt acgagtttta ataagaatat tttatgttgc cgtatagtgt catcagttca
    29161 aaacacatta aatttaaaca ttaatttggg tagaaataaa cggtttaatg atgaagtatc
    29221 taaactggat tcaagtacaa ttttaatgtc ggcctctgct ggaggtagaa aaggtgttca
    29281 gtttaaagta gtatgtcatt ctaaggttac ggatggtgaa gtaagtgtat tgggagagac
    29341 aatagttatt cggaatgcta cagaggtatt tctttatctc aaatcaatga cggattattg
    29401 gggaaatata gatatttctt ctcttcaggg agaatttagt agtattgatt actttacaga
    29461 aaaagatgaa catgtaaaaa aatatcagga gcaatttaat agagttgatt ttaaactaga
    29521 ctatagtaaa ggttgtctta gcattccaac gaatctactt cttgaaaaca ctaaaaagta
    29581 tagtaactac ttgactaact tgttatttca ttatggaaga tatctgttaa tatcgtctag
    29641 tcaaccgaat ggtttacctg ccaatcttca aggaatatgg tgtgatgaat taaatccaat
    29701 ttggggttct aaatatacga ttaatattaa tactcaaatg aattattgga tggtaggtcc
    29761 atgtgattta ccagaagtag aatatccatt atttgatatg ctcgaaagaa tgagagaacc
    29821 gggaagacta accgctaaga aaatgtatgg agctagaggt tttacagcac atcataatac
    29881 ggatggtttt ggcgatacgg ctccccaatc tcatgccatg ggggctgcaa tttgggtatt
    29941 aactattcca tggttatgta ctcatatttg ggaacactat ttatatttcc aagatgagcg
    30001 tattcttacg gaacattttg aaatgataaa agaagcattt cttttctttg aagattattt
    30061 atttgaggtg gatggctact tgatgacagg tccaagtgtc tcaccggaaa ataaatatcg
    30121 cttaaaaaat ggtattgaag gaaatgcttg tctatcatct acaattgata atcaaatttt
    30181 aagatatttt tgtgattcat gcattggaat tgcaaaacaa ttaggagaca attcggattt
    30241 tattagtcgt gtgaaggagt taaaaaagaa attacctaga acaaaaatag gtagtaatgg
    30301 gcaaatacaa gaatggctag aggattatga agaagtagag cctggtcata gacacatttc
    30361 acctctattt gggctttatc cttataatga gattgatatt cataaaactc cggaattagc
    30421 agaagcagct aaaatcacta tcaataggag attatcaaac gctaactttt tatcttcaca
    30481 ggatagggag caagcgatta ataattggtt agtaagtggt ttgcatgcta gtacacaaac
    30541 aggttggagt gctgcatggc tgattcattt ttttgcgaga ctatatcaag gtgaacctgc
    30601 ttataaccag attaatggtt tgttaaataa tgcgactctt ggcaatttat ttcttgacca
    30661 tccaccattt caaattgatg gtaatttagg tttggtgagt ggaatttgtg aattattagt
    30721 acagagccat cataattggt tatcactaat tccagcttta ccttctgctt ggtcagaagg
    30781 agaagtgaaa ggtttcagag taagaggagg atataaggta tcgtttgctt ggaaaaatgg
    30841 ggatataaca ttcctaaaat tggaaggagg aaacaaagat caaaaagtaa gagtaagaat
    30901 atatggcaaa aatactgatg tacaaaatat tgaattggta tttaattcag aaaaaattat
    30961 tgagttaaat ttttaggtat aagtcatgaa taaagaaaaa ataaaaagaa aattaatcac
    31021 aatactgttt gtatgtattg ggatgttatg ttttggattg ttagcaggag ttaaggctga
    31081 taatcgtgtt caaatgagaa cgacgattaa taatgaatcg ccattgttgc tttctccgtt
    31141 gtatggcaat gataatggta acggattatg gtgggggaac acattgaagg gagcatggga
    31201 agctattcct gaagatgtaa agccatatgc agcgattgaa cttcatcctg caaaagtctg
    31261 taaaccaaca agttgtattc cacgagatac gaaagaattg agagaatggt atgtcaagat
    31321 gttggaggaa gctcaaagtc taaacattcc agttttcttg gttattatgt cggctggaga
    31381 gcgtaataca gttcctccag agtggttaga tgaacaattc caaaagtata gtgtgttaaa
    31441 aggtgtttta aatattgaga attattggat ttacaataac cagttagctc cgcatagtgc
    31501 taaatatttg gaagtttgtg ccaaatatgg agcgcatttt atctggcatg atcatgaaaa
    31561 atggttctgg gaaactatta tgaatgatcc gacattcttt gaagcgagtc aaaaatatca
    31621 taaaaatttg gtgttggcaa ctaaaaatac gccaataaga gatgatgcgg gtacagattc
    31681 tatcgttagt ggattttggt tgagtggctt atgtgataac tggggctcat caacagatac
    31741 atggaaatgg tgggaaaaac attatacaaa cacatttgaa actggaagag ctagggatat
    31801 gagatcctat gcatcggaac cagaatcaat gattgctatg gaaatgatga atgtatatac
    31861 tgggggaggc acagtttata attttgaatg tgccgcgtat acatttatga caaatgatgt
    31921 accaactcca gcatttacta aaggtattat tcctttcttt agacatgcta tacaaaatcc
    31981 agctccaagt aaggaagaag ttataaatag aacaaaagct gtattttgga atggagaagg
    32041 taggattagt tcattaaacg gattttatca aggactttat tcgaatgatg aaacaatgcc
    32101 tttatataat aatgggagat atcatattct tcctgtaata catgagaaaa ttgataagga
    32161 aaagatttca tctatattcc ctaatgcaaa aattttgact aaaaatagtg aggaattgtc
    32221 tagtaaagtc aactatttaa actcgcttta tccaaaactt tatgaaggag atgggtatgc
    32281 tcagcgtgta ggtaattcct ggtatattta taatagtaat gctaatatca ataaaaatca
    32341 gcaagtaatg ttgcctatgt atactaataa tacaaagtcg ttatcgttag atttgacgcc
    32401 acatacttac gctgttgtta aagaaaatcc aaataattta catattttat tgaacaatta
    32461 caggacagat aagacagcta tgtgggcatt atcaggaaat tttgatgcat caaaaagttg
    32521 gaagaaagaa gaattagagt tagcgaactg gataagcaaa aattattcca tcaatcctgt
    32581 agataatgac tttaggacaa caacacttac attaaaaggg catactggtc ataaacctca
    32641 gataaatata agtggcgata aaaatcatta tacttataca gaaaattggg atgagaatac
    32701 ccatgtttat accattacgg ttaatcataa tggaatggta gagatgtcta taaatactga
    32761 agggacaggc ccagtccctt tcccaacacc agataaattt aatgatggta atttgaatat
    32821 agcatatgca aaaccaacaa cacaaagttc tgtagattac aatggagacc ctaatagagc
    32881 tgtggatggt aacagaaatg gtaattttaa ctctggttcg gtaacacaca ctagggcaga
    32941 taatccctct tggtgggaag tcgatttgaa aaaaatggat aaagttgggc ttgttaaaat
    33001 ttataatcgc acagatgctg agactcaacg tctatctaat tttgatgtga ttctatatga
    33061 caataataga aacgaagttg ctaagaaaca tgttaataat ttgtcgggtg aatctgttag
    33121 tctagatttc aaagaaaaag gagcaaggta tattaaagtt aaattactaa cgagtggagt
    33181 gcctttgagt ttagcagaag tagaggtttt tagagaatca gatggtaagc aatctgaaga
    33241 ggatatagat aaaataacag aagataaagt agtctctaca aataaggtag ctactcaaag
    33301 ttcaaccaat tatgagggtg tagctgcttt agcagttgat ggtaataaag atggagatta
    33361 cggacatcat tcggtgactc atactaaggc agattctaac gcttggtggc aggttgatct
    33421 gggagaagag tttacggttt ctaaagttga tatttataat agaacagatg ccgaacctca
    33481 gcgtttatct aattttgatg ttatttttct atcttcatca ggagaagaag tttttagaag
    33541 acattttgat aaagtagttg atggtttgtt atctttaaaa gtaccttctg taggggctaa
    33601 gctagtcaaa atagaattaa aatcagcagc tattccgtta agtttagcgg aagttgaagt
    33661 ctatggttca aagagaactc cgaagaaact ttctaatatt gcattaacca aagaaactcg
    33721 acagagttca acggattaca atggtttttc tcgtctagca gttgatggaa ataaaaacgg
    33781 agattatggt catcattcag tgactcatac caaaggagat tctccttcat ggtgggagat
    33841 agatttagca caaaccgaag aattagaaaa gttaattatt tataatagaa cagatgctga
    33901 aattcagaga ttatcaaatt ttgatattat tatatatgat tcaaataatc atgaagtttt
    33961 taaacaacat attgacagtt tagaaagcaa taatctatcc atagacttaa aagggctgaa
    34021 gggaaaaaag gttagaattt ctttgagaaa cgcaggaatt cctttaagtt tagcagaggt
    34081 agaggtttat acttataagt aattttaaaa attatcaccc aggctaccgt aaatataatg
    34141 gagatggtag tatgaaagaa acagaaaaat aagaggaaaa tagtatgatt caacatccac
    34201 gtattgggat tcgtccgact attgatggtc gtcgtcaagg tgtacgcgaa tcacttgaag
    34261 tgcaaacaat gaacatggct aaaagtgtgg cagatttgat ttcaagcaca ttgaaatatc
    34321 cagatgggga acctgtggaa tgcgtgattt ctccatctac tattggccgt gtaccagagg
    34381 ctgcagcttc ccatgagttg tttaaaaaat caaatgtttg cgcaacaatt acagttacac
    34441 catgctggtg ttatggtagt gaaactatgg atatgtctcc agatattcct catgctattt
    34501 ggggatttaa tgggacagaa cgcccaggag ctgtctatct tgcagctgta ctagcttcac
    34561 atgctcaaaa agggattcca gcctttggga tttatggaag agatgttcag gaagctagtg
    34621 acacagatat tccagaagat gtcaaagaaa aacttttacg ctatgcgcgt gcagctcttg
    34681 caactggctt gatgagagac actgcttacc tatcaatggg tagtgtttcg atggggattg
    34741 gtggttctat tgtaaatccg gatttcttcc aagaatactt aggaatgcga aatgaatcgg
    34801 tagatatgac ggagttcaca cgccgtatgg accgtggtat ttacgaccct gaagagttcg
    34861 aacgtgcgct caaatgggtg aaagaaaacg taaaagaagg attcgaccat aaccgtgaag
    34921 accttgtttt aagccgtgaa gaaaaagata gacaatggga atttgttatt aagatgttca
    34981 tgattggacg tgacttaatg gttggtaacc caagacttgc tgaccttggt tttgaagaag
    35041 aagcagttgg tcaccatgct ttagtagctg gtttccaagg tcaacgccag tggacagacc
    35101 atttcccaaa tggggacttt atggaaactt tcctcaatac tcagtttgac tggaatggta
    35161 ttcgaaaacc atttgtattt gcgacagaga atgattcact aaatggtgtg tctatgctct
    35221 ttaattatct attaacaaat actccacaaa tctttgctga tgtgcgcact tattggagtc
    35281 cagaggctgt taaacgtgta acgggacata ctttagaggg ttgtgctgca gctggcttct
    35341 tacatctaat caactctggt tcttgtacat tggatggtac aggtcaagct actcgagatg
    35401 gcaaacctgt tatgaaacca ttctgggagt tggaagaaag tgaagtgcag gctatgcttg
    35461 aaaatacaga cttcccacca gcaaaccgcg aatacttccg tggaggagga ttctcaactc
    35521 gtttcttgac gaagggggat atgccagtaa caatggtacg tctcaatctt ctaaaagggg
    35581 ttggtccagt gctacaaatt gcagaaggtt atacacttga acttcctgaa gatgttcacc
    35641 atactttaga taatcgtaca gatccaggat ggccaactac ttggtttgct ccacgtttga
    35701 caggaaaagg tgctttcaag tctgtctatg acgtcatgaa taattgggga gctaatcacg
    35761 gagccataac atatggacac attggagcag acttgattac cttggcttct atgttgagaa
    35821 ttcctgtcaa tatgcataat gtacccgaag aagatatctt tagacctaaa aattggtcct
    35881 tatttggaac agaagatcta gaatcagcag actatcgtgc atgtcagtta ttgggaccac
    35941 tacataaata aaacttgttt atataggagg tgaacttacg tccctcctat ccttttaaaa
    36001 agatttgtta aacaattcac aaataattga aaacgaatac aaaaagtaat ataatgatgt
    36061 taaatagata gcgcggaggc gcaggaggaa aattatatgg ctacatttta tgttccggca
    36121 gtcaacctta ttggaaaagg tgttgtaaat gaagtgggtc cttatatcaa ggaacttggc
    36181 tataaaaagg cacttttggt tacagataag tacatcgaag gcagtgatat tttacctaag
    36241 actttaaaac cactggatac agaaggaatc gaatatgtca tctttagcga tgtagagcca
    36301 aaccctactt gtaaaaatgt cacagatggg gtagctgctt tgcaagaaca tggctgtgac
    36361 tttatcatca gtcttggcgg gggttctcca caggatgcag ctagttgtat ttctatcatg
    36421 gctacaaatg gtggaaaacc acaggattat gaagggcttc ataagtctgc taaaaaaggc
    36481 ttgccagttg tggctatcaa tacaacggca ggaacttctg cagaaatcac tattaactat
    36541 gtgattactg atgaagaacg caaggttaag atggtaatgg ttgacaagaa tagccttgct
    36601 cttatctctg ttaatgaccc ggaactcatg ctttccaaac ctaaaggcct gactgctact
    36661 actggtatgg atgctctgac tcacgctgtt gaagctttgg taacacctgg tgcttatgat
    36721 gtaaccaaga aactgtctat tggtgctatt gagcttatca aggaatatct tcctcgtgct
    36781 gtagaaaatg gacatgatat tgaagcgcgt gaaggtatgg tcaatgccat cttccttggt
    36841 ggtatgagct ttaataatgc tggtcttggt tatgttcact caatggctca ccaactcggt
    36901 gcagtatata atttgccaca tggcgtgtgc tgtgccatgt tgctaccagt tatagaacgt
    36961 gaaaatgcta aacgtgtacc agaagctttc cgcaatgttg ccaaagcctt gggacttcat
    37021 gtagaaggta aatcagatca agaatgtgcc gattatgcga ttgctgagat tgagaagctt
    37081 tctgagacag taggtattcc taagaaactg actgaacttg gtattgaaga aaaagatttc
    37141 gactttgaat acctttctaa gaatgccttg attgatgcct gcgcaccagg aaatccattt
    37201 atgccaacct tagaagaaac gattgccttt tataaagagt tattttagca agagattgga
    37261 cgacaatagg acaattcacc tctaattatt gacatttcag gaaaaatcgc agtaaaaacg
    37321 gcacagcctt ctttaaatgt gctataatac tagaaaaata cttgtggagg ttccattatg
    37381 gcaatatttt tcatgatttt tctgattgtt tgtgtgctcc tattggtgat agtcacactg
    37441 agtacagttt atgtggttcg tcagcagtcg gtggcgatta ttgaacgctt tgggaaatac
    37501 caaaaggttg ctaatagcgg tattcatatt cgcttgcctt ttgggattga ctcgattgca
    37561 gcacggattc agctgcgctt gttgcaaagt gatattgtgg ttgagactaa gaccaaggac
    37621 aatgtgttcg ttatgatgaa tgtagcgact cagtaccgtg tcaacgagca gagcgtgaca
    37681 gatgcttact ataaactcat acgtccagaa tctcagatta aatcttatat cgaagatgct
    37741 cttcgctctt ctgttccaaa attaaccttg gatgaattgt ttgagaaaaa agatgagatt
    37801 gcccttgagg ttcaacacca agtagcagaa gaaatgacca cttacggcta cattatcgtg
    37861 aaaaccttga ttaccaaagt cgaaccggat gcagaagtta agcaatccat gaatgaaatc
    37921 aatgcggcgc aacgtaagcg ggtcgcagca caagaattgg cggaagctga caagattaaa
    37981 attgtcactg cagctgaagc cgaagcagaa aaagaccgcc ttcatggtgt ggggattgcc
    38041 caacaacgta aggcgattgt ggatggattg gcagagtcta tcaccgaact caaggaagcc
    38101 aatgttggca tgacagaaga acaaatcatg tctatcctct tgactaacca gtatttggat
    38161 accttgaata cctttgcctc taaaggaaat caaaccatct ttttaccaaa tacgccaaat
    38221 ggtgtggatg atatccgaac acaaatcttg tcagcccttc gcgctgagaa gaaataatag
    38281 actaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttgccg tatagatgtt
    38341 actgacttcg tcagttctat ctgcaacctc aaaacagtgt tttgagctga cttcgtcagt
    38401 cttatctact accttaaaac ggtgttttga gctgacttcg tcagtcttat ctactacctc
    38461 aaaacggtgt tttgagcaac ctgtggctag tttcctagtt tgctctttga ttttcattga
    38521 gtacaaagag cttggcaaca ggctcttttt gtattgcgtt tattaagaaa aacaaaaaac
    38581 atcgatatac atttaactaa aaattattgt atgttatctc tcttaattag gaatgataag
    38641 ggaataacta gaaagatttg tgaatacaaa ctatttctga tatacaaaat atacagtaat
    38701 aatgaatgat gggagatggg atgaaagaat ttcaatttga gagaaagcag cgtttttctt
    38761 tgaggccata tgcaatagga gcttgttcgg tcttgctagg aacgagttta ttttttgatg
    38821 gtatgggtga tcagcctgta caggatacag aaacgagttc agcactaatt ttaagtcatt
    38881 atttggatga gcaggattta tctgaaaagc tgaaatctga gttgcaatgg cttgaattag
    38941 aaaacaagct tttgaactta tgggagcatt aggttactat gaaggatttg ttccttatgt
    39001 ttcaaattaa tacaaaaacc aagctgaaga agaagacaaa ccgctatctg ataaatatat
    39061 tttcgaaaaa atattaggaa aaacatatgc agccttcaaa aaagatcaaa ttaatgagcg
    39121 tgtcgagaaa ttaggtaagt taaaacctat tacaataaat tacaacggaa aatcagaagt
    39181 aattgatagt aaagaaaaat tacaagagct tatgaataaa gccgttaaag acgaagtggc
    39241 tcaaatatag taaaatgaaa taagaacagg acaaatcaat caggacagtc aaattgattt
    39301 ctaaaaatgt tttagaagta gaggtgtact attctagttt caacatacta taaaatcagg
    39361 caatacaacg gctaaaaagt ttgagtttat cgaaatacca gtgcaaaaac tgaaaaaagc
    39421 gatttataaa gctcatctca aagattcaga t
//
LOCUS       DAVDFK010000016        38465 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.16, whole genome shotgun sequence.
ACCESSION   DAVDFK010000016 DAVDFK010000000
VERSION     DAVDFK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.16"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VUR04_001056"
     CDS             complement(56..1066)
                     /locus_tag="VUR04_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET5340963.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VUR04_001057"
     CDS             1215..2384
                     /locus_tag="VUR04_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5340964.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VUR04_001058"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VUR04_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET5340965.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VUR04_001059"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VUR04_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET5340966.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VUR04_001060"
     CDS             4146..4379
                     /locus_tag="VUR04_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET5340967.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VUR04_001061"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VUR04_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VUR04_001062"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VUR04_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET5340968.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5862..8015
                     /locus_tag="VUR04_001063"
     CDS             5862..8015
                     /locus_tag="VUR04_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET5340969.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELVEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8028..9377
                     /locus_tag="VUR04_001064"
     CDS             8028..9377
                     /locus_tag="VUR04_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET5340970.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGTEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9547..10254
                     /locus_tag="VUR04_001065"
     CDS             9547..10254
                     /locus_tag="VUR04_001065"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET5340971.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10456..14181
                     /locus_tag="VUR04_001066"
     CDS             10456..14181
                     /locus_tag="VUR04_001066"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET5340972.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKIIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGILEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVLFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14274..15716
                     /locus_tag="VUR04_001067"
     CDS             14274..15716
                     /locus_tag="VUR04_001067"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET5340973.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15753..16775
                     /locus_tag="VUR04_001068"
     CDS             15753..16775
                     /locus_tag="VUR04_001068"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET5340974.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLSLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16772..17317
                     /gene="purN"
                     /locus_tag="VUR04_001069"
     CDS             16772..17317
                     /gene="purN"
                     /locus_tag="VUR04_001069"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET5340975.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQIG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17401..17910
                     /locus_tag="VUR04_001070"
     CDS             17401..17910
                     /locus_tag="VUR04_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET5340976.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17935..19482
                     /gene="purH"
                     /locus_tag="VUR04_001071"
     CDS             17935..19482
                     /gene="purH"
                     /locus_tag="VUR04_001071"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET5340977.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKDALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19604..20866
                     /gene="purD"
                     /locus_tag="VUR04_001072"
     CDS             19604..20866
                     /gene="purD"
                     /locus_tag="VUR04_001072"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET5340978.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQLILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21269..21757
                     /gene="purE"
                     /locus_tag="VUR04_001073"
     CDS             21269..21757
                     /gene="purE"
                     /locus_tag="VUR04_001073"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET5340979.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAAIFALRLLSVEDKSIADALANFAEEQGKIAEESTNE
                     LI"
     gene            21744..22835
                     /gene="purK"
                     /locus_tag="VUR04_001074"
     CDS             21744..22835
                     /gene="purK"
                     /locus_tag="VUR04_001074"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET5340980.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLAERCDVLTYEFENVDADGLDAVVKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVDSSQDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22845..23072
                     /locus_tag="VUR04_001075"
     CDS             22845..23072
                     /locus_tag="VUR04_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET5340981.1"
                     /translation="MIQIIVNTFIEKDRTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23135..24433
                     /gene="purB"
                     /locus_tag="VUR04_001076"
     CDS             23135..24433
                     /gene="purB"
                     /locus_tag="VUR04_001076"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET5340982.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24488..28330)
                     /gene="strH"
                     /locus_tag="VUR04_001077"
     CDS             complement(24488..28330)
                     /gene="strH"
                     /locus_tag="VUR04_001077"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET5340983.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSLQSSENRTEETPKAELQPEAPKTVETKTPTSAEKETANKKAEEASPKK
                     EEAKEVDSKESNTDKTDKDKPAKKDEAKAEADKPETEAGKERAATVNEKLAKKKIVSI
                     DAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVK
                     RAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKEL
                     GIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDA
                     TDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSD
                     TSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWY
                     NLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANA
                     NAEYFAADYESAEQALNEVPKDLNRYTAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQ
                     AIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNKVISIDAGRKYFTLNQLKRIVDKA
                     SELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTAL
                     TQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDL
                     KNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAE
                     YANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLA
                     SKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGS
                     MLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPTNLEGYSKES
                     LEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGLKPAATHSGSLDENEVAANVET
                     RPELITRTEEIPFEVIKKENPNLPAGQENIITAGVKGERTHYISVLTENGKTTETVLD
                     SQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKPRLDIQKEEIPFTTVTRENPLLLK
                     GKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDE
                     NGQAAIAEEKPKLEIPSQPAPSTAPAEESKALPQDPAPVVTEKKLPETGTHDSAGLVV
                     AGLMSTLAAYGLTKRKED"
     gene            complement(28645..29361)
                     /locus_tag="VUR04_001078"
     CDS             complement(28645..29361)
                     /locus_tag="VUR04_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5340984.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERVNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29709..31496
                     /locus_tag="VUR04_001079"
                     /pseudo
     CDS             29709..31496
                     /locus_tag="VUR04_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
     gene            31493..31969
                     /locus_tag="VUR04_001080"
     CDS             31493..31969
                     /locus_tag="VUR04_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET5340985.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDMEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            31997..32902
                     /locus_tag="VUR04_001081"
     CDS             31997..32902
                     /locus_tag="VUR04_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5340986.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32889..33704
                     /locus_tag="VUR04_001082"
     CDS             32889..33704
                     /locus_tag="VUR04_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5340987.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVVYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33711..34115
                     /locus_tag="VUR04_001083"
     CDS             33711..34115
                     /locus_tag="VUR04_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5340988.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDMLAGFDDDEDE"
     gene            34414..35580
                     /locus_tag="VUR04_001084"
     CDS             34414..35580
                     /locus_tag="VUR04_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET5340989.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKYDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35696..36733
                     /locus_tag="VUR04_001085"
     CDS             35696..36733
                     /locus_tag="VUR04_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET5340990.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            36940..37794
                     /locus_tag="VUR04_001086"
     CDS             36940..37794
                     /locus_tag="VUR04_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5340991.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            37944..38201
                     /locus_tag="VUR04_001087"
     CDS             37944..38201
                     /locus_tag="VUR04_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET5340992.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT        10784 a         7417 c         9116 g        11148 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 gaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagagagtga tggggatgat agctagggtt cgcgtgagtt
      421 tgacaatggt tgcggattcg agggtattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga agtttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagtggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagt
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cttcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagc tgaagataaa gcctataacc
     4561 atgcgctatc caaggagaga agcaaggttg agaacatctt tgccaaagta aaaacgttta
     4621 aaatgatttc aacaacctat cgaaatcatc gtaaacactt cggattacga atgaatttga
     4681 ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt cgatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaagagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgcctaggg
     5521 tgacagtaaa aaatcaattt cctttcatat catattttta gtagatagga tgtttgttct
     5581 gtctattttt tgccaaaaaa agtgcagttg ggagggagat aggctcattt gggaaggaag
     5641 tccagttttt gtttagtgat tggggtaaga tagttgttat cagatgagtt tatactcttc
     5701 gaaaatcaaa ttcaaaccac gtcaacgtcg ccttgccgta tatatgtgac tgacttcgtc
     5761 agtcctatct acaacctcaa aacagtgttt tgagcagcct gcggctagtt tcctagtttg
     5821 ctctttgatt ttcattgagt attagggaaa aggagatgaa tatgaaattt gggaaacgtc
     5881 actatcgtcc gcaagtggat cagatggact gcggtgtagc ttcattagcc atggtttttg
     5941 gctactatgg tagttattat tttttggctc acttgcgaga attggctaag acgaccatgg
     6001 atgggacgac ggctttgggc ttggtcaagg tggcagagga gattggtttt gagacgcgag
     6061 ccattaaggc ggatatgacg ctttttgact tgccggattt gacttttcct tttgttgccc
     6121 atgtgcttaa ggaagggaaa ttgctccact actatgtggt gactgggcag gataaggata
     6181 gcattcatat tgccgatcca gatcccgggg tgaagttgac taaactgcca cgtgagcgtt
     6241 ttgaggaaga atggacagga gtgactcttt ttatggcacc tagtccagac tataagcctt
     6301 ataaggaaca aaaaaatggt ctgctctctt ttatccctat attagtgaag cagcgtggct
     6361 tgattgccaa tatcgttttg gcaacactct tggtaaccgt gattaacatt gtgggttctt
     6421 attatctgca gtctatcatt gatacctatg tgccagatca gatgcgttcg acactaggga
     6481 ttatttctat tgggctagtc atcgtctaca tcctccagca aatcttgtct tacgctcagg
     6541 agtatctctt gcttgttttg gggcaacgct tgtcgattga cgtgattttg tcctatatca
     6601 agcatgtttt tcacctccct atgtccttct ttgcgacacg caggacaggg gagatcgtgt
     6661 ctcgttttac agatgctaac agtatcatcg atgcgctggc ttcgaccatc ctttcgattt
     6721 tcctagatgt gtcaacggtt gtcattattt cccttgttct attttcacaa aataccaatc
     6781 tctttttcat gactttattg gcgcttccta tctacacagt gattatcttt gcctttatga
     6841 agccgtttga aaagatgaat cgggatacca tggaagccaa tgcggttctg tcttcttcta
     6901 tcattgagga catcaacggt attgagacta tcaagtcctt gaccagtgaa agtcagcgtt
     6961 accaaaaaat tgacaaggaa tttgtggatt atctgaagaa atcctttacc tatagtcgag
     7021 cagagagtca gcaaaaggct ctgaaaaagg ttgcccatct cttgcttaat gtcggcattc
     7081 tctggatggg ggctgttctg gtcatggatg gcaagatgag tttggggcag ttgattacct
     7141 ataatacctt gctggtttac tttaccaatc ctttggaaaa tatcatcaat ctgcaaacca
     7201 agcttcagac agcgcaggtt gccaataacc gtctaaatga agtgtatcta gtagcttctg
     7261 agtttgagga aaagaaaaca gttgaggatt tgagcttgat gaagggagag atgactttca
     7321 agcaggttca ttacaagtat ggctatggtc gagacgtctt gtcggatatc aatttaaccg
     7381 ttccccaagg gtctaaggtg gcttttgtgg ggatttcagg gtcaggtaag acgactttgg
     7441 ccaagatgat ggttaatttt tacgacccaa gtcaagggga gattagtctg ggtggtgtca
     7501 atctcaatca gattgataaa aaagccctac gccagtacat caactatctg cctcaacagc
     7561 cctatgtctt taacggaacg attttggaga atcttctttt gggagccaag gaggggacga
     7621 cacaggaaga tatcttacgg gcggtcgaat tggtagagat tcgagaggat atcgagcgca
     7681 tgccactgaa ttaccagaca gaattgactt cggatggggc agggatttca ggtggtcaac
     7741 gtcagagaat cgctttggcg cgtgctctct tgacagatgc gccggtcttg attttggatg
     7801 aggcgactag cagtttggat attttgacag agaagcggat tgtcgataat ctcatggctt
     7861 tggacaagac cttgattttc attgctcacc gcttgactat tgctgagcgg acagagaagg
     7921 tggttgtctt ggatcagggc aagattgtcg aagaaggaaa gcatgctgat ttgcttgcac
     7981 agggtggctt ttacgcccat ttggtcaata gctagaaaga ggagaggatg aaaccagaat
     8041 ttttagaaag tgcggagttt tataatcgtc gttaccataa tttttccagt agtgtgattg
     8101 tacccatggc ccttctgctc gtgtttttac ttggctttgc aactgttgca gaaaaggaga
     8161 tgagtttgtc cactagagct actgtcgaac ctagtcgtat ccttgcaaat atccagtcaa
     8221 ctagcaacaa tcgtattctt gtcaatcatt tggaagaaaa taagctggtt aagaaggggg
     8281 atcttttggt tcaataccaa gaagggacag agggtgtcca agcggagtcc tatgccagtc
     8341 agttggacat gctaaaggat caaaaaaagc aattggagta tctgcaaaag agcctgcaag
     8401 aaggggagaa ccactttcca gaggaggata agtttggcta ccaagccacc tttcgcgact
     8461 acatcagtca agcaggcagt cttagggcta gtacatcgca acaaaatgag accatcgcgt
     8521 cccagaatgc agcagctagc caaacccaag ccgaaatcgg caacctcatc agtcaaacag
     8581 aggctaaaat tcgcgattac cagacagcta agtcagctat ggaaacaggt gcttccttgg
     8641 ccagtcagaa tctagcctac tctctttacc agtcctacaa gtctcagggc gaggaaaatc
     8701 cccaaactaa ggttcaggca gttgcacagg ttgaagcaca gatttctcag ttagaatcta
     8761 gtcttgctac ttaccgtgtc cagtatgcag gttcaggtac ccagcaagcc tatgcgtcag
     8821 ggttaagcag tcaattggaa tcccttaaat cccaacattt ggcaaaggtt ggtcaggaat
     8881 tgacccttct agcccagaaa atcttggagg cagagtcagg taagaaggta cagggaaatc
     8941 ttttagacaa ggggaaaatt acggcgagtg aggatggggt gcttcatctt aatcctgaga
     9001 ccagtgattc tagcatggtt gcagaaggtg ccctactagc ccaactttat ccatctttgg
     9061 aaagagaagg gaaagccaaa ctcacagcct atctaagttc aaaagatgta gcaagaatca
     9121 aggtcggtga ttctgttcgc tatactacga ctcatgatgc cgggaatcaa cttttcctag
     9181 attcaactat tacaagtatt gatgcgacag ctactaagac tgagaaaggg aatttcttta
     9241 aaatcgaggc ggagactaat ctaacttcgg agcaggctga aaaacttagg tacggggtgg
     9301 aaggccgctt gcagatgatt acgggcaaga aaagttatct acgttattat ttggatcaat
     9361 ttttgaacaa agagtaatgt tcgtgttttt agagttaaat aatttttaaa ctgtgagaaa
     9421 gattcttctt gcagtttttt ctttacaatt tttgaaaaac atctactatt tattcggtta
     9481 aattcttgtg ttttttggtt ttttgtggta aaatgtgctc aagtaatacg aaaggcgaac
     9541 tttaaaatgt caaaacaatt gatctattcg ggaaaagcta aagatatcta tacaactgag
     9601 gatgaaaatc ttattatttc aacttacaag gaccaggcga ctgctttcaa cggtgtcaag
     9661 aaggagcaga ttgcaggtaa gggagtcttg aataatcaga tctcatcttt tatttttgag
     9721 aaattaaatg cggctggtgt ggcgactcac tttgtggaga aactttcaga cacggaacaa
     9781 ctcaataaaa aggttaagat tattcctttg gaagtcgtgc tccgcaacta tactgctggt
     9841 tccttttcaa aacgttttgg tgtggatgag ggaatcgcct tggagactcc gattgtcgaa
     9901 ttttactaca aaaatgatga tttggatgat ccatttatca atgatgagca tgtgaaattc
     9961 ctacagattg cgggtgacca gcagattgcc tacttgaagg aagaaacgcg tcgtatcaat
    10021 gaactattga aagtctggtt tgctgagatt gggcttaaat tgattgactt taagctagag
    10081 ttcggttttg acaaggatgg caagattatc ttggcagacg aattttcacc agataactgc
    10141 cgcttgtggg acgctgatgg caaccacatg gataaggatg ttttccgtag aggattggga
    10201 gaactaaccg acgtttatga gattgtttgg gaaaagttgc aggaattgaa ataatctgtt
    10261 tgcaacggaa aaccttcgtc tctcaactaa aaggactcag gctgaaaagg tcccccagac
    10321 cttttcactc tgtagagaac taggtgaact aacagatgtt tacgaaattg tctgggaaaa
    10381 gttgcagggt ttaaaataac aacctcaagg ctgtttggga atattgcaag agctgaaata
    10441 aaggaataag aattgatgga taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc
    10501 aagtcagaga gtttggttag agagctccag cacaacttgg gactgtcaag cttgaaaagt
    10561 attcgtattg tgcaagtata tgatgtattt gacttggctg aggacttgtt tgcacctgca
    10621 gagaagcaca ttttctctga gcaggtaacc gaccatgttt tagatgaagt atctgtgcag
    10681 gcggatcttg ctaactatgc tttctttgcc attgaaagtc tgccagggca gtttgaccag
    10741 cgtgcagctt cgtcacagga agccttgctt ttgttgggaa gttcgagtga cgtgacagtc
    10801 aacacagccc aactttactt ggtgaataaa gatattgatg cgactgagtt ggaagctgtc
    10861 aaaaactacc tgctcaatcc agttgattct cgtttcaagg atatcacgac agggattgcc
    10921 aagcaggagt tttcagagtc agacaagatc attccaaaat tgactttctt tgaaagctat
    10981 acagcagaag actttgctcg ctacaaggcc gaacaaggga tggccatgga agtggatgat
    11041 ttgctcttta tccaagacta ctttaagtca atcgggcgcg tgccaactga gactgaactc
    11101 aaggttttgg acacttactg gtctgaccac tgccgtcata cgacttttga gacagagttg
    11161 aaacacatcg acttttcagc ttctaaattt caaaagcaat tgcagtcaac ctatgacaag
    11221 tatattgcca tgcgcgagga attaggtcgg tctgaaaaac cacaaacctt gatggatatg
    11281 gcgactattt tcggtcgtta tgagcgtgct aatggacgat tggatgatat ggaagtctct
    11341 gacgaaatca atgcctgctc agttgaaatt gaagtggacg ttgatggtgt caaggaacct
    11401 tggcttctca tgtttaaaaa cgaaacccac aaccatccaa cagaaattga gccatttggt
    11461 ggagcggcta cctgtattgg tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt
    11521 taccaagcca tgcgtatttc aggtgctggt gatattacag caccgatttc ggaaactcgc
    11581 gctgggaaat tgccacaaca agtcatttct aaaacagcag ctcatggtta ttcttcatat
    11641 ggtaaccaga ttgggcttgc aacaacctac gttcgtgaat acttccaccc aggctttgta
    11701 gctaaacgta tggaacttgg tgccgttgtt ggtgcggctc ccaagggcaa tgttgtccgt
    11761 gaaaaacctg aagcaggtga tgtgatcatc cttctcggag gcaaaacagg tcgtgatggt
    11821 gtcggtggtg cgacgggctc ttctaaggtt caaacagttg agtctgtaga gactgctggt
    11881 gctgaggttc aaaaaggaaa tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat
    11941 ggcaatgtca ctcgtctgat caagaagtcc aatgactttg gggcaggcgg tgtctgtgtg
    12001 gctatcggtg aattggcaga cggtcttgaa atcgacctca acaaggtgcc tcttaaatac
    12061 cagggcttga atggtacaga aattgccatc tctgaatcac aagaacggat ggcggtcgtg
    12121 gttcgtcctg aagatgtgga tgccttcgtt gccgaatgta acaaagaaaa tattgatgct
    12181 gttgtggtgg cgacagtaac tgaaaaacca aatcttgtca tgcactggaa tggtgagaca
    12241 atcgttgact tggagcgtcg tttccttgac accaatggtg tgcgcgtggt tgtcgatgcc
    12301 aaagttgtgg acaaggatgt caaactccca gaagagcgtc aaacatctgc tgaaacactg
    12361 gaatcagata cccttacggt tctatctgac ctcaaccatg caagtcaaaa aggattacag
    12421 actgtctttg actgctctgt tggacgctca acggttaatc acccacttgg tggtcgttac
    12481 caactcacac caactgaggc atctgtgcag aaattgccag ttcaacacgg tgtgactcat
    12541 actgcgtcgg tcattgctca aggtttcaac ccatatgtag ctgaatggtc tccataccac
    12601 ggtgctgctt acgcggttat cgaagcaact gctcgtttgg tggctgctgg tgccaactgg
    12661 tctaaggctc gtttctctta ccaagaatat ttcgagcgga tggacaagca agcagagcgt
    12721 tttggtcagc cagtagccgc ccttctaggc tctattgaag ctcagattca acttggcttg
    12781 ccatctatcg gtggtaagga ctccatgtct ggtacctttg aagaattgac cgttccgcca
    12841 accttggttg cctttggggt gacgacggca gatagccgta aggtgctctc tccagaattt
    12901 aaagctgttg gggaaaatat ctactacatc ccaggtcaag ccctctctgc agagattgat
    12961 tttgacttga ttaagaaaaa ttttgctcag tttgaagcaa gccaagctga ccataaagtg
    13021 acatctgcat cagctgtcaa atacggtggt gtagttgaaa gtttggctct tgctaccttt
    13081 ggaaactata ttggtgcaga ggtgaccttg cctgaactta aaacagcttt gacagctcaa
    13141 ttaggcggct ttgtcttcac atctcctgaa gaaattgctg gagtagagaa gattggacaa
    13201 acgaaagcag actttacact gactgtcaac ggtgtgaagc tagatggaca caagcttgac
    13261 agtgcatttc aagggatatt ggaagaagtt tacccaacag aatttaccca agcgaaagaa
    13321 ctagaagaag taccagctgt ggcatcagat gttgtgatta aagccaaaga aaaggttgaa
    13381 aaacctgtgg tttacatccc agtctttcca ggaaccaact cagaatatga ttcagctaag
    13441 gccttcgaaa aagaaggtgc agaggtcaat ttggtgctat tcgtgacctt gaatgaagaa
    13501 gctattgtca agtcagttga aactatggtt gacaatatcg acaagactaa tattctcttc
    13561 tttgccggtg gattctcggc tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat
    13621 atcctgctta atgaaaaagt gcgtgtggct attgatagct ttatcgcccg tggtggcttg
    13681 attatcggta tttgtaatgg attccaagcc ttagtcaaat cgggtctcct accatacgga
    13741 aactttgaag atgctaacag tactagtcca accctcttct acaatgatgc caaccaacac
    13801 gtggccaaga tggtggaaac tcgcattgcc aataccaact caccatggtt ggctggtgtg
    13861 caagtgggcg atatccacgc tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg
    13921 gctgaggaat ttgcagagct ccgtgacaat ggacaaattt tcagccaata cgttgacttt
    13981 aacggtaaac caagtatgga ttctaagtac aatccgaatg gttctgtcca tgccatcgaa
    14041 ggaattacca gcaagaatgg tcaaatcatc ggtaagatgg gccactcaga acgttatgag
    14101 gatggtcttt tccaaaatat cccaggcaat aaagaccaac acctgttcgc atcagcggtt
    14161 aaacatttca ctggaaaata agacttacag attttctaat agatagtatc agtaatgtaa
    14221 aagtcatgta aatctagctc ttgatgatta caaatgaaaa ttaggtataa aaaatgacat
    14281 acgaagtaaa atctcttaat gaagaatgtg gtgttttcgg tatttgggga catccagatg
    14341 ctgctaagtt gacctatttt ggactccaca gtcttcaaca ccgtggtcag gagggggcag
    14401 gaatcctctc caacgatcaa ggacaactga agcgccatcg tgacatgggg cttttatcag
    14461 aagttttcag aaatccagct aatttggata aattgacagg agctggtgcg attgggcatg
    14521 tgcgttatgc gactgctggc gaagcttctg tagataacat ccagcccttc ctcttccgtt
    14581 ttcacgatat gcagtttggc ttggctcata atgggaatct gaccaatgca gcctctctca
    14641 agaaagaact ggaacaaaga ggagcaattt tcagcgctac ttcggactct gaaatcttgg
    14701 ctcacctcat tcgtcgtagt cataatccta gcctgatggg caaaatcaag gaagcgctca
    14761 gccttgtcaa aggtggtttt gcctatatct tgctgtttga ggacaagttg attgcggctc
    14821 ttgacccaaa tggattccga ccgctttcga ttggtaaaat ggctaatgga gcagttgttg
    14881 tatcttctga aacctgtgct tttgaggtca ttggtgccga gtggattcgt gatttgaagc
    14941 caggtgagat tgtgatcatt gatgacgagg gcattcagta tgacagctat acagatgata
    15001 cccagttggc ggtttgttct atggagtata tctactttgc tcgccctgat tctaatatcc
    15061 acggtgtcaa tgtccatacg gcacgtaaga gaatgggagc acaattggcg cgagaattta
    15121 agcatgaggc agatattgta gttggtgtgc ccaattcttc cctaagcgcg gctatgggat
    15181 ttgcggaaga atcaggctta ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc
    15241 gaacttttat ccaaccgact caagaattgc gggagcaagg agtgcggatg aaactgtctg
    15301 ctgtttcggg tgttgtcaaa ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg
    15361 gaacaacctc tcgtcgtatc gttcagctct tgaaagaagc gggtgcgact gaggttcacg
    15421 ttgccattgg aagtcctgca ctagcgtatc catgtttcta cgggattgat atccagaccc
    15481 gtcaggagct gattgcagcc aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg
    15541 acagtctgac ttatctttca attgatggct tgattgagtc gattggtatc gaaacagatg
    15601 cgccgaacgg tggtctctgt gtcgcttact ttgacggtga ctacccaacg cctctctatg
    15661 actacgaaga agactatcgt agaagtttgg aagaaaagac cagtttttac aagtaggcga
    15721 cagattctcc attaaagaaa aggaaaaaac aaatgacaaa taaaaatgca tatgcccagt
    15781 cgggtgtgga tgttgaagcg ggttatgaag ttgttgaacg gattaaaaag cacgtggctc
    15841 gtacggagcg tgcaggtgtc atgggagctc ttggtggctt tggtggtatg tttgaccttt
    15901 ccaagactgg ggttaaagaa cccgtcttga tttcagggac tgacggtgtc ggaaccaagc
    15961 tcatgttggc tatcaagtac gacaagcacg ataccatcgg gcaggactgt gtggccatgt
    16021 gtgtcaacga catcattgct gcaggtgcgg aacccctcta ttttctcgac tacgtagcga
    16081 cagggaagaa tgagccagct aagctagaac aagtggttgc tggtgtggca gaaggttgtg
    16141 tgcaggctgg tgctgccctc atcggtgggg aaacggctga aatgccgggc atgtacggcg
    16201 aagacgacta tgacttggct ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg
    16261 acggttcaaa ggtggtagag ggagatgttc ttctcggact tgcttcaagt gggattcact
    16321 caaatggtta ctctttggtt cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac
    16381 cagaattgga aggcaagaaa cttaaagaag ttctacttga gccgactcgt atctatgtca
    16441 aggctgtctt gtcgctcatc aaagaagagt tggtcaacgg cattgcccac atcacaggtg
    16501 gtggctttat cgaaaatgtc cctcgtatgt ttgcagatga cctagctgct gaaattgatg
    16561 aaagcaaagt tccagtgctt ccaattttca aagcccttga aaaatatggt cagattaaac
    16621 acgaagaaat gtttgaaatc ttcaatatgg gtgtgggact tatgttggcg gtcagccctg
    16681 aaaatgtaga gcgtgtaaaa gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg
    16741 tcaagaaaga aaacgaaagt gtcattatca aatgaaaaaa atagcggttt ttgcctctgg
    16801 taatggctca aattttcagg tgattgccga agaatttcca gtggagtttg tcttttcaga
    16861 ccatcgtgat gcctatgtgc ttgagcgtgc aaagcagatc ggcgttctgt cctatgcttt
    16921 tgaactcaag gagtttgaga gcaagacaga ctacgaagca gcccttgtcg aactcttgga
    16981 agaacaccag attgacttgg tttgcctagc aggctacatg aaaatcgttg gaccaacctt
    17041 attgtcggct tatgaaggtc ggattgtcaa cattcatcca gcctacttgc cagaatttcc
    17101 aggagctcat gggattgagg atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat
    17161 tcactgggtg gattcgggtg tggatacagg ccaggtcatc aaacaggttc gtgtgccacg
    17221 actagctgat gataccattg acagatttga agctcgcatc catgaagcag agtacaggtt
    17281 gtatccggaa gtagtgaagg ctctatttac agattgactt tttgatgatt catatgatat
    17341 ctttgatttt aaattggagt cagtgtttgt tgaagacggc ttcaaacgga ggtatttgta
    17401 atgttagaat ctaaaaaaac aactcgatat gtattttatg tctatctgat gttattaact
    17461 tggggaatct tatttaagtt tgaaacaaat cctgaattta tagcattttt cttagctcca
    17521 aggtatatca attggattcc attttcagaa ccactaatag tcgatggaaa aattgttttt
    17581 gctgaaatgt tatttaatct gatttccttt attccattag gtgtttgttt ccctttgata
    17641 aaaactaatt tatctagttt aagaatagtc gggacaggtt tcttgattag tttattgttt
    17701 gagtgcttac agtatatttt agcaataggt ataacagata taacggattt gactttaaat
    17761 acgctaggtg tctgtgtagg cttactgatt tatcaaattt ttataagagt gttcaaatca
    17821 cagactagaa aatggatcaa tatcttaggt atgcttagcc ttggttttgc ttatcttgtt
    17881 ttactgttac tgcatttaat tggtgtttaa ctaatgatta aaaaggagaa tataatgact
    17941 aaacgcgtct taatcagcgt ctcagacaaa gcgggcattg ttgaatttgc ccaagaactc
    18001 aaaaaacttg gttgggagat tatctcaaca ggtggaacta aggatgctct tgataatgct
    18061 ggggtggata ccattgctat cgatgatgtg actggtttcc cagaaatgat ggacggtcgt
    18121 gtgaagaccc tccacccaaa tatccacgga gggcttctcg ctcgtcgtga cttggatagc
    18181 cacttggaag cggctaagga caacaagatt gagctcattg accttgtggt ggtcaacctt
    18241 tacccattta aggaaactat ccttaaacca gatgtgactt atgctgatgc agttgaaaat
    18301 atcgatattg gtgggccgtc tatgcttcgt tcagcagcga aaaatcatgc cagtgttaca
    18361 gttgtggtag atcctgctga ctacgctgtg gttttggacg aattggcagc aaacggcgaa
    18421 acctcttatg aaactcgcca acgtttagca gccaaagtat ttcgtcacac agcggcttat
    18481 gacgccttga ttgcagaata cttcacagct caagtgggtg aaagcaagcc tgaaaaactc
    18541 actttgactt atgacctcaa gcaaccaatg cgttacggtg agaatcctca acaagacgcg
    18601 gacttttacc agaaagcttt gcctacagat tactctattg cttcagccaa acagctcaac
    18661 gggaaagaat tgtcatttaa taatatccgt gatgcagatg ctgctatccg tatcatccgt
    18721 gacttcaaag atagtccaac cgttgtggct ctcaaacaca tgaatccatg tggaattggt
    18781 caagctgatg acatcgagac tgcttgggac tacgcttatg agtctgaccc agtatctatc
    18841 tttggtggga ttgtcgtcct caaccgtgag gtggatgctg cgacagctga gaagatgcac
    18901 ggcgttttcc tcgaaatcat cattgcacca agctatacgg atgaagcgct agctattttg
    18961 atcaataaaa agaaaaactt gcgtatcctt gccttgccat ttaatgctca agaggctagc
    19021 gaagtggaag cagaatacac aggtgtagtc ggtggacttc tcgtgcaaaa tcaagacgtg
    19081 gtcaaggaaa gcccagctga ctggcaagtg gtgaccaaac gtcagccaac tgagacagaa
    19141 gcgactgctc ttgagttcgc ttggaaggct atcaagtacg tcaaatcaaa tggtattatc
    19201 gtgaccaacg accacatgac acttggtgtt ggtccaggtc aaaccaaccg tgtggcttct
    19261 gttcgccttg ccattgacca agccaaagat cgtctgaacg gggcggtcct tgcttcagat
    19321 gccttcttcc catttgcgga taacgtggaa gaaatcgcca aagcaggaat taaggccatc
    19381 atccagcccg gtggctctgt ccgtgaccaa gaatccatcg aagcagcgga taaatacggc
    19441 ttgactatgg tctttacagg tgtgagacat tttagacatt aagaagataa aagggaagaa
    19501 aacagtttct ttcctttttt ggcttaaaat gctaactgaa acaagattaa aacgaacttt
    19561 tttgatataa tgttggtaaa taattcgcaa aagaggttga ggaatgaaac tgcttgttgt
    19621 cggttctggt ggtcgtgagc atgcgattgc taaaaagtta cttgaatcaa aagacgtgga
    19681 aaaagtcttt gtagctcctg ggaatgatgg gatgactctg gatggtttgg aattggtaaa
    19741 tatctctatt tccgaacatt ctaaattgat tgacttcgca aagaccaatg atgttgcttg
    19801 gacctttatc ggtccagatg atgcccttgc tgctggcatc gtggatgatt ttaaccaagc
    19861 tggacttaag gcctttggtc cgactagggc tgcagcggag ctggagtggt ccaaggattt
    19921 cgccaaggaa atcatggtca aatacggcgt tccgacagca atatatggca cattttcaga
    19981 tttcgaggaa gccaaggcct atatcgaaaa gcatggtgcg cctatcgtag tcaaggcgga
    20041 tggcttggca cttgggaagg gtgtcgtcgt tgctgagacg gttgagcaag cggtcgaagc
    20101 cgctcatgag atgcttttgg acaataaatt tggtgactca ggtgcgcgcg tggttattga
    20161 ggaattcctt gaaggagagg aattttcact ctttgccttt gtcaatggtg ataagttcta
    20221 catcatgcca acggctcagg accacaaacg tgcctatgat ggcgacaaag ggcctaacac
    20281 gggtggtatg ggtgcctatg cgccagttcc acacttacca cagagtgtag ttgatacagc
    20341 ggttgacacc attgtcaagc cagttctaga aggggtgatt aaagaaggtc gtccttatct
    20401 gggagttctt tacgcagggc ttatcctgac agctgatgga ccgaaagtca tcgagttcaa
    20461 cgctcggttc ggagatccag aaactcagct tatcttgcct cgcttaacct ctgactttgc
    20521 tcaaaatatc acagatatcc tggatagcaa ggagccaaat atcacgtgga cggacaaggg
    20581 tgtgactctg ggtgtggttg tcgcatccaa gggctacccg ctagattatt caaagggtgt
    20641 tgagttgcca gtcaaaaccg atggcgacat cattacctac tatgcagggg ctaagtttgc
    20701 ggaaaatagc agagcactgc tctcaaacgg cggacgagtt tatatgctcg ttaccacagc
    20761 agataccgtc aaagaagccc aagccagcat ctaccaagaa ctatcccaac aaaaaataga
    20821 aggactcttc taccgaacag atatcggaag caaggcaatt aagtaaagat ataagaataa
    20881 cgcgccgtag tcgccaaaca cgataatggt cgtcgtggtg aaaagaccag aacagtgaat
    20941 gttctggtca gggggaaact tggagaccgt aggctcaaag tttaggaatg aaaccgaagg
    21001 tttgcttccg cctccatcac ctaagaccat tatcaaaaag aaaaataaaa attcacaaaa
    21061 tacgttaatg gtcgtatggt ttgcgagcgt tagcgagcta atatagaata atcaccgccg
    21121 ttgtgaaaga acgattggat gacaatccaa tcgttcaggg aaattggaag accttaggtt
    21181 tccaatttag gcatgagaca cctttggtgg ctgctgccgt ccctcacaag ctaaggtgat
    21241 tgttgaaaaa gaggaaaaag gagaagaaat gaaaccagta atttccatca tcatgggctc
    21301 aaaatccgac tgggcaacca tgcaaaaaac agcagaagtc ctagaccgct tcggtgtagc
    21361 ctacgaaaag aaagttgttt ccgcacaccg cacaccagac ctcatgttca aacatgcaga
    21421 agaagcccgt agccgtggca tcaagatcat catcgcaggt gctggtggcg cagcccattt
    21481 gccaggtatg gtcgctgcca aaacaaccct tccagtcatt ggtgtacctg tcaagtctcg
    21541 tgctcttagt ggagtggatt cactctattc tatcgttcag atgccgggtg gggtgcctgt
    21601 tgcgaccatg gctataggtg aagctggagc gactaacgca gctatctttg ccctccgtct
    21661 cctctctgta gaagataagt ccattgcgga tgcacttgcc aactttgctg aagaacaagg
    21721 aaaaatcgca gaggagtcta ccaatgagct catctaaaac aatcggaatt atcggtggcg
    21781 gtcagctggg tcagatgatg gccatttctg ctatctacat gggtcataag gttatcgcgc
    21841 tggatcctgc agcggattgc ccagcctctc gtgtggcgga aatcattgtg gcgccttata
    21901 acgatgtgga tgcccttcgt cagctagctg agcgttgcga tgtcctgact tatgaatttg
    21961 agaatgtaga tgctgacggt ttggatgcgg ttgtcaagga tgggcaactt ccacaaggga
    22021 cagacctact ccgtatttct caaaatcgca tctttgaaaa ggacttcctc tcaaacaagg
    22081 cacaagtcac tgtggcaccc tacaaggttg tggattcaag ccaagacttg gcagatattg
    22141 acctatcgaa aaactatgtc cttaagactg cgactggtgg ctacgatggt catggacaaa
    22201 aggttattcg ttcagaagca gacttggaag cagcctatgc gctagcagac tcagcagcct
    22261 gcgtcttgga agaatttgtc aactttgacc ttgagatttc tgtcatcgtg tcaggaaatg
    22321 gcaaggaggt gacgtttttc ccagttcagg aaaatatcca ccgcaacaat atcctgtcta
    22381 agaccatcgt accagcccgc atttctgaaa gtctagtaga caaggctaaa gctatggcag
    22441 tgcgaatcgc agaacaactc aacttgtctg gaactctctg tgtggaaatg tttgcgactg
    22501 atgatgacgt tattgtcaat gaaatcgccc cacgaccaca taactctggg cactattcta
    22561 ttgaagcctg tgatttctct cagtttgaca cccatattct cggtgttctc ggagcaccat
    22621 taccagtcat caaactccat gcgccagccg ttatgcttaa tgtcctcggt cagcatgtcg
    22681 aggctgctga gcaatatgtg acagaaaatt caagcgccca cctccacatg tatggtaaaa
    22741 tagaagcgaa gcacaaccgc aagatgggac atgtgacctt gtttagtgat gtaccggata
    22801 gtgtggatga gcttggggaa gggattgatt tttaggacaa gtctatgata caaattatcg
    22861 ttaatacatt tattgaaaag gataggactg gagcagttgt tgaagtgttg tatgccagtg
    22921 ctgaccaaga taaggtacaa gctaaatatg aagaactagc tgcacaatac cccgaaaatt
    22981 atttagctat ctatgatgta ccgctggata cggatttgaa tacactagat cattacccgt
    23041 ctgtgtttat tgaaaaagag gagtttgagt agaaatcttg gtttacctag atagcttatt
    23101 cccaacagct taagaagaaa ggaaaaatta acacatgatc aaccgttact ctcgccctga
    23161 gatggcgaat atttggagtg aagaaaataa ataccgtgct tggcttgagg tggaaatcct
    23221 ctctgacgag gcatgggctg agttggggga aatccctaag gaagatgtgg ctttgattcg
    23281 caagaaggcg gactttgaca tcgaccgtat tttggaaatt gagcaggaga cgcgccacga
    23341 tgtggtggct ttcacgcgtg cggtttctga gactcttggt gaagagcgca agtgggttca
    23401 ctatgggtta acttctaccg acgtggtgga tactgcttat ggttacctct acaagcaggc
    23461 caacgacatc atccgtcgtg accttgaaaa cttcactaat atcatcgctg acaaggccaa
    23521 ggagcacaag ttcaccatca tgatggggcg tactcatggt gtgcacgctg agccgacaac
    23581 ctttggtctt aaattggcaa cttggtacag cgaaatgaaa cgcaatatcg agcgtttcga
    23641 gcatgcagct gctggtgtag aagctggtaa gatttctggt gcggttggga actttgccaa
    23701 tatcccacca tttgtagagg agtatgtctg cgataaactt ggcatccgtg cccaagaaat
    23761 ctctacacaa gtccttcctc gtgaccttca cgctgagtac tttgcggttc ttgccagcat
    23821 tgcgacttca atcgaacgta tggcgactga gattcgtggt ctacaaaaat ctgagcaacg
    23881 cgaagtagaa gagttctttg ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg
    23941 caacccaatc ggttctgaaa atatgactgg tctggcgcgt gtcattcgtg gtcacatgat
    24001 tacggcttat gaaaacgtcg ctctctggca cgaacgcgat atttctcact catcagctga
    24061 gcgtatcatc acaccagata cgaccatttt gattgactac atgctcaacc gttttggaaa
    24121 tatcgtcaag aacttgacag tcttcccaga aaatatgatc cgaaacatga actcgacttt
    24181 tggtcttatc tttagccaac gggctatgtt gacattgatt gaaaaaggca tgacccgtga
    24241 gcaagcctat gacttggtgc aaccaaaaac agcctactct tgggacaacc aagtagactt
    24301 taaaccactt cttgaggcag attcagaagt aacatcacgt ctcactcaag aagaaatcga
    24361 tgaaatcttc aacccagttt attacaccaa acgagtggat gatatctttg aacgtcttgg
    24421 actaggtgat taattaaaaa ataaacagcg agcttcaatc tcgctgttta ttttttatcg
    24481 aaaagactta gtcttctttt cttttagtga gtccataggc tgctagtgtg gacatgagtc
    24541 ctgcgactac tagtcctgca gaatcgtgag ttcctgtttc aggaagtttt ttctctgtta
    24601 ccacaggagc tggatcttga ggaagagctt tgctttcctc agcaggagca gttgatggag
    24661 ctggttggct tgggatttct agttttggtt tttcttcagc aatagcggct tgtccgtttt
    24721 catcgcctac atgtgttacc atagttccga cttcgactat ttgagtaacg gcttcctgtg
    24781 ctacgacact atttacaagt gttttcactt ccttaccatc ggcagaagtg ctcacagagt
    24841 agaagttgct acgatgtcca ttgacgccct tagtaatgac ttgtgttttt cctttgagta
    24901 agagtggatt ttcacgagtc actgtggtaa atggaatttc ttctttttgg atatccagtc
    24961 taggttttac ctcagtagtt ggtgcaagac cactttcatc acccttgtga gttacaggag
    25021 cgccaacttc aaccacttgg tttataactt ctttggttac ctggctatca aggactgttt
    25081 ctgttgtttt tccattttca gtgagtacag agatgtaatg agttcgttca cctttgactc
    25141 ctgctgtgat aatattttcc tgaccagctg ggaggttagg attttctttc ttgataactt
    25201 caaatggaat ttcttcagtt cttgtgatga gttctggtct ggtttcaaca ttggcagcca
    25261 cttcattttc atccaggctt cctgaatgag ttgcagctgg tttgaggcct tgaagagcgg
    25321 cttttaggtt ggctacaagt gtgtcaagct cagcttgttt attacggttg aggttgtaat
    25381 ttagagctgt tttagctgcg tcaagggcct caagactttc tttactatat ccttctaagt
    25441 ttgtaggaat tttagctaat tcttcgcgga gagcattata attagcacgg aagtagtctt
    25501 tgttgtggtc tgcaaaggca gtcatgagtt caaagatttc ctcttccttg tattcagcgc
    25561 ttggtctatc tgcccagatt gaaagcatac ttccgactgt tggaagatct acttcaggat
    25621 atttggtaga agctagttga ttgaatggtg tttttccagt attctcaata gctttcttga
    25681 ggaaaccacc accatcttct ggtttttgac caagaatgta gtaccagtca ccgttggtat
    25741 tcaagaattt atagcctttg cttgctaggt attgaggtga tgcgaggtta tatccccacc
    25801 agcctttaga ccagtaagaa atcaagacat ctttgtcaaa ctgaacatcg tccttgtctt
    25861 catagtagaa gccatcgttg aaggccattg gttgaagccc tctttctttg gccatagctg
    25921 cgagggtgtt ggcatattcg gcaaatttgc catagagttg ataccacttg aggtagtacc
    25981 agccttgggc actagtcgca tcgttggcgt attcgtcagt accaaagttg aaaatctttg
    26041 ttttacctgc aaagaagtcc atgtatttac cgatgagggc ttttacaaag ttcatcgctt
    26101 cttcgttttt caagtccata gttgtttttg aaactttatc aaagtgggct tgaggatttt
    26161 taatacctaa tttttccatg gcaaccagca tagcatccat gtgacctgga ctgttaatag
    26221 ctgggatgag accgatgtcc ttagatttag cgtattcaat tagctctgtt acttctgcct
    26281 gtgttagtgc agtaccgttt ggatcgtcgt agtaagcttt agttccttcg ataatagctt
    26341 ttttaacgtc atcactagca taggtttttc cgttggcagt aatggtcata tcatcgagta
    26401 gaaagcgaag tccgtcattt cctagaagga gatggacatc agaatatccg agctcactgg
    26461 ccttgtctac gatgcgtttg agctggttca gagtaaagta tttgcgtcca gcatcgattg
    26521 agattacctt gtttttggca agtttttcaa cctcacgttt agcttcttct tctttttgag
    26581 cttcaggcgt gagggtcaag ttgttgacag tttcttgaag tttagcaatg gcttgatcaa
    26641 tcgtatcttg ttgggcacgg ctaaggttgc tatcgagaga gcgaatagct ttttcagctt
    26701 cttttacggc cgtgacgctt tctgcagtat aacggttcag gtcttttggt acctcgttaa
    26761 gtgcttgctc tgcagattca taatcagctg cgaagtattc agcgttggca tttgcaaaat
    26821 gacgcatgag tttgaagagg cgtgatggtg aataacgtgc agatggagtg tcagcccaag
    26881 cagctaccat accaccgatg attgggatat cagctccttc tgtttttggt acagaagtga
    26941 ttggtgtgtt tttaatacca ttgagcccct gatcgagatt gtaccagcct tggccatcag
    27001 cgtttcgtcc aagaacgtag taccaagcat cattggtatt aaggatttgg tgaccttttt
    27061 cagctagtag tttagaagaa gcgacatcgt agcctcccca accaccagtc cacatagaaa
    27121 cgatgatgtc tttgtcaaaa ctaccaaagc ttgtgtcgct attgtagtag ataccgtcgt
    27181 taaaggccat tggtttgaga ccgtgcgatt ttacaatacg agcgaggtca ttggcgtagg
    27241 caataaattt ttcatagcct tttacagggt agccttcgtt tggatagtat ttatcagctt
    27301 gaagcacact ccaaccttta gcatctgtcg catcattggc atattcatca agtccgatgt
    27361 tgaagatttc agtctttttc gcgaaataag cagcatactt gtcgataagg gcttttgtaa
    27421 aagcgacagc ttgttcgttg tcaagatcga cagtacgggc tgatttcttc ccaaaatagc
    27481 taaagttagg gttttggatt cccaattctt tcatggcatt gagaatcgca tccatgtgtc
    27541 caggactatt tactgtcgga atgagaccga tacctttatc tttggcatag ttaatcagat
    27601 ctgtcatttg actttctgtt aagtgattgc cgtttggatc gttgtaataa tcatttgtac
    27661 ctttttcaat ggcgcgtttg acatcgtcac tggcataggt cttgccgtta gctgtgatgc
    27721 tcatatcgtc caacatgaaa cggagtccat catttccgac taataggtgt aaatcagtgt
    27781 agccataatg tttcgcttta tcgatgattt ccttgagctg ttctggtgag aaatatttac
    27841 gtccagcatc aatagaaaca attttctttt tcgctagttt ttcatttaca gttgcagcac
    27901 gttcctttcc tgcctctgtt tccggtttgt cagcctctgc tttcgcttca tcttttttag
    27961 ctggtttatc cttgtcagtc ttgtctgtat ttgactcttt agaatcaacc tctttcgctt
    28021 cttccttttt agggctagct tcttctgcct ttttattagc agtttctttt tcagcagaag
    28081 ttggagtttt tgtttctaca gtttttggag cttctggttg aagctctgct ttaggtgttt
    28141 cctcagtccg attttcggat gattgaaggg aatcagaaac cgtatggata gtcggttggt
    28201 tttctgtagt agtaggagta actccatcgg ctgcaacagt ctgtgcttgg aaggcaaatc
    28261 caattagaac agaagctgct cctacagcgt atttacgaat agaaaaacgc tgttgttttt
    28321 catgtttcat tgcaaaacct cctgattgca ttgttatatt gatagcgatt atataaatca
    28381 acgcctttat tttatttctt atattaacga gagtcaagag gagatgacaa aaaactataa
    28441 taagtataaa aaaatataaa atttaaactt aagatttcag attggtcgga aaaaatacgt
    28501 atatatatct agtataattt ttggttctat ttctataaaa tattccacaa attatagaat
    28561 tttccaaaaa taggtaagcg ctaccttttt ggtgtagtat aataagcata gaaaaagccc
    28621 aagcgattag ctcaggtttt cttcttagtg atcacggtca catgagataa atttaatctt
    28681 gtagtaatca gatcgtttgt aagtttcact gtattctaaa acttggccag ttgattcgag
    28741 tttggtgatt ttagtttgta ggacagtagg gaattgttca tcgactccga ggactgaagc
    28801 cgcatgttct ggagttggaa agactatttc gttgatttct tcaaagtgtt catcattcat
    28861 gtgaatgtgg tagtctaact tgaaacgatt atagatagaa ctatagtatt caaggtttgg
    28921 ataatttgcg ttgatatatt gttctgggat gtaggatgta tggtagatat aaacgacacc
    28981 gtttgattcg cggatacgtt caatcttgta gtagaattga tcgccgcgta gacccaattt
    29041 ttccaagtaa acaagcttgt ttacgcgttc aattgaaaga acagttacct tatcatcttt
    29101 agcattgaag agttcaatat ctgaaaactc tacaagcttg tgtttgcgtg cacgtgaaac
    29161 gaaggttcct tttccttgtt ggcggacaat atagccatct ttggcaaggt cgtttaaggc
    29221 acgaacaact gtgatagagc tgacatcgta cattgaaatg agttctgctt cagtgtaaaa
    29281 tttatctcca ctgctaaact gcccagagat gattttattt tttaattcgt cttttatgta
    29341 ttgatatttg ggaattgcca tatttttacc tctattttcc ttctccatag aaaattttac
    29401 cataaaagcg aaaaaaatag tagtcttttg aataaaaaat tagaataata gtttgaaaaa
    29461 ttaagcgata tagggattgc tcatatttta tcaatgtatt ctatacaaaa ttattttagg
    29521 tcctatattc cgaatttaaa gagcgtttga aatgggtcta aaaatgtttg aaactaattg
    29581 aatgtgtgta taatagtaaa aatgcagtaa atatcccgac aatttctatt gacaattcaa
    29641 acagattggt ttataattaa tataacaaca aatgaaagcg caaactttcg cggtcggaag
    29701 gtagttttat gacacgattt gagatacgag atgatttcta tctcgatgga aaatcattta
    29761 agattttatc tggtgccatt cattatttta gggttcctcc agaggattgg tatcattcgc
    29821 tctataactt gaaggctctt ggttttaata cggtagagac ttatgttgct tggaatttac
    29881 acgagcctcg tgaaggtgag tttcattttg aaggtgatct ggatttagag aaatttctcc
    29941 aaatagcgca ggatttgggt ctctacgcaa ttgtgcgtcc gtctccattt atctgtgcgg
    30001 aatgggaatt cggtggctta ccagcttggc tcttgaccaa gaacatgcga attcgctcat
    30061 ccgacccagc atatatcgag gcagttggtc gctactatga tcagttattg ccaagactgg
    30121 tgcctcgttt gttggacaat ggtggcaata ttctcatgat gcaggttgaa aatgagtatg
    30181 gttcttacgg agaagataag gcttacctga gagcgattcg acagctaatg gaagagtgtg
    30241 gcgtaacctg tcccctcttt acatcagatg gtccgtggcg agctactctg aaagctggaa
    30301 ccttaattga agaggacctc tttgtaacag gaaactttgg ttctaaggca ccttacaact
    30361 tttcgcagat gcaggaattc tttgatgaac atggtaagaa atggccactc atgtgtatgg
    30421 agttctggga tggttggttc aatcgctgga aagaaccgat tatcacacgg aatcctaagg
    30481 aattggcaga tgcagttcga gaggttttgg aacaaggctc tatcaatctt tacatgttcc
    30541 acggtggtac aaactttggt ttcatgaatg gttgctcagc tcgaggaact ttggacctgc
    30601 cacaagttac gtcttatgat tacgatgccc ttctggatga agaaggaaat ccaactgcta
    30661 aatatcttgc agtcaagaag atgatggcaa cacatttttc agagtatccg cagttggaac
    30721 cactctacaa agagagtatg gagttggatg ctattccact agttgaaaaa gtttctttgt
    30781 ttgaaacctt agatagcttg tcaagtcctg tagaaagtct ctatcctcaa aagatggagg
    30841 agctgggaca aagttatggc tacctacttt atcgaacaga aacaaactgg gatgcagaag
    30901 aagaaagact tcgtatcatt gatggtcgag atagggccca gctgtatgtc gatggtcagt
    30961 aggttaaaac tcaatatcag acagagattg gggaagatat tttttatcaa ggtaaaaaga
    31021 aagggctatc taggttagat atcttgatag aaaatatggg gcgtgtcaac tatgggcata
    31081 agttcttagc ggatacgcaa cgtaagggaa ttcggacagg ggtctgtaag gatctgcatt
    31141 tcttactaaa ctggaaacac tatccactcc cactagacaa tcctgagaaa attgattttt
    31201 caaaaggatg gactcaagga caaccagcct tttacgctta tgactttaca gtcgaagagc
    31261 caaaagatac ttacctagac ttgtctgagt ttggtaaggg ggttgccttt gtcaatgggc
    31321 agaatctagg acgtttttgg aacgttggcc caactctctc actttatatc cctcatagct
    31381 atctcaagga aggtgccaac cgcatcatta tctttgaaac agaaggtcaa tataaagaag
    31441 agattcattt aactcgtaaa cctacactaa aacatataaa gggggaaaac ttatgacaat
    31501 tgtaggatgc cgtattgatg gacgtttgat ccacggacaa gtagccaatc tttgggctgg
    31561 aaaactaaat gtttcacgca ttatggttgt agacgacgaa gttgtcaaca acgatattga
    31621 aaagagtggt ttgaaacttg cgacaccacc aggtgtgaaa ttgagtattt tgccagttga
    31681 gaaagctgca gccaatattc ttgctggcaa atacgatagc caacgtctct ttatcgtggc
    31741 tcgtaaacca gaccgcttcc ttggtttggt agaagcaggt gtaccacttg aaacccttaa
    31801 tgttgggaat atgtctcaaa caccagaaac tcgttctatt acacgttcta tcaacgtagt
    31861 agacaaggat atggaagact tccacaaact ggcagaaaaa ggtgttaaac ttactgctca
    31921 gatggttcca aatgatccaa tttcagactt tttgagctta ttaaaatagg aaaaaaattt
    31981 ttaggaggtc attgttatga tacaatggtg gcaaatttta cttctcactt tgtactcagc
    32041 ttatcaaatc tgtgatgagt tgacgatcgt ttcatctgca ggttcccctg tatttgctgg
    32101 tttcattact ggtttaatca tgggagatgt gactactggt ttacttatcg gtggtaactt
    32161 gcaactgttc gttcttgggg ttggtacctt cggtggtgct tctcgtatcg acgcaacttc
    32221 tggtgcggtt cttgcgacag ccttctctgt ttcacaagga attgatgcac cgcttgccat
    32281 tactacaatc gctgtaccag tagcagctct cttgacttac ttcgacgttc ttggtcgtat
    32341 gactactacc ttcttcgctc accgtgtgga tgctgcaatc gaacgctttg actataaagg
    32401 tattgaacgc aactacttgc ttggtgcgat tccgtgggct ctatctcgtg cccttccagt
    32461 cttctttgcc cttgcttttg gtggtgcctt tgtacaatca gtagtagact tcgttgaagc
    32521 ctacaaatgg gttgcagatg gcttgacact tgcaggacgt atgcttccag gtcttggatt
    32581 tgcaatcttg cttcgttacc ttccagttaa acgtaacctt cactaccttg ctatgggatt
    32641 tggtttgaca gctatgttga ctgttcttta ctcatatgta acaggtcttg gtggcgctgt
    32701 tgctggtatc gtaggtactc ttcctgctga agttgctgaa aaaattggtt tcgtgaacaa
    32761 cttcaaaggt ttgtctatga ttggtatttc tatcgtaggt attttccttg cagtgcttca
    32821 cttcaaaaat agccaaaaag tagctgtagc agcaccttct acaccatcag aaagtgggga
    32881 aatcgaagat gacgaattct aattacaaac ttacaaaaga agattttaat caaatcaaca
    32941 aacgtagctt gtttactttc caattaggtt ggaactacga acgtatgcaa gcttctggtt
    33001 acctttacat gatcttgcct cagttgcgta aaatgtatgg tgatggaact cctgaattga
    33061 aagaaatgat gaaagttcat actcaattct tcaatacttc accattcttc cataccatta
    33121 tcgctggttt tgaccttgcc atggaagaaa aagatggtgt aggttcaaaa gacgccgtta
    33181 acggtatcaa gacaggtttg atgggaccat tcgctcctct tggggataca atctttggtt
    33241 cacttgtacc tgctatcatg gggtcagtcg cagcaactat ggctatcgct ggccaacctt
    33301 gggggatctt cctttggatt gcagttgcag tagtgtatga catcttccgt tggaaacagt
    33361 tggaatttgc ttacaaagaa ggggttaacc ttatcaacaa catgcaaagt accttgacag
    33421 ctttgattga cgctgcatct gtacttggtg tcttcatgat gggtgctctt gtagcaacag
    33481 tgattaactt tgaaatttct tacaagttgc caatcggtga aaagatgatt gatttccaag
    33541 acatcttgaa ccaaatcttc ccacgtttgc ttccagcaat ctttactgcc tttatcttct
    33601 ggttgcttgg taagaaaggt atgaactcta ctaaagctat cggtattatt atcgtacttg
    33661 ctttggctct ttctgccctt ggtcactttg cacttggaat gtaattcctt atgactaaat
    33721 cattaatttt ggtgagccat ggtcgcttct gtgaggagct tagaggtagc acagaaatga
    33781 ttatgggccc acaagacaac atttacacag tagctcttct tccagaagat ggcccagaag
    33841 aatttactgc taaatttgaa gctgttattg gaggattgga tgatttccta gtctttgcgg
    33901 atcttctcgg tgggacacct tgtaatgtgg tgagtcgctt gatcatggaa ggtcgtgata
    33961 ttgaccttta cgcagggatg aatcttccaa tggtgattga atttatcaat gcgagcctta
    34021 caggcgcaga tgcggactac aagagccgtg ctgcagaaag cattgtgaaa gttaatgaca
    34081 tgttagcggg cttcgatgat gacgaagatg aataatactc ttcgaaaatc tcttcaaact
    34141 acgtcaacgt cgccttgccg taggtatatg ttactgactt cgtcagtctt atccggcaac
    34201 ctcaaaacgg tgttttgagc tgacttcgtc agtcttatcc ggcaacctca aagcagtgct
    34261 ttgagcagcc tgcggctagt ttcctacaga ttttagttgg aactcgattc aattcatgtg
    34321 acaacgtgaa aatcgttaga gcattttata tagaatatac atgggaatgg agcttactcc
    34381 cattcctata tttaatagaa aaagaggaac tcaatgctac attatacaaa agaagacttg
    34441 ctcgaattgg gtgcagaaat cactacgcgt gaaatctacc aacagcctga tgtatggaga
    34501 gaagcttttg aattttatca agcaaaacgt gaagaaattg cagcctttct acaagaaatc
    34561 gctgataaat atgactatat taaagttatc ttgacaggtg ctgggacttc tgcttatgtg
    34621 ggagatacct tgctacctta ttttaaggaa gtctatgacg aacgcaaatg gaatttcaat
    34681 gctattgcga caacagatat cgttgccaat ccagcaacct atttgaaaaa agatgtggca
    34741 actgtccttg tgtcttttgc tcgtagtggg aactcgcctg aaagtgtggc gactgttgat
    34801 ttggccaaat ccttggtgga tgagctttat caagtgacga ttacttgtgc agcagatggt
    34861 aaattggctc ttcaagctca cggtgatgac cgtaatctct tgctcttgca accagctgtc
    34921 tctaatgatg ctggatttgc catgacttct agctttacgt ctatgatgtt gacagctctc
    34981 ttggtctttg atcctacaga atttgctgtt aagtctgaac gttttgaagt tgtatctagt
    35041 cttgcccgta aagttttaga caaggcagaa gatgtcaaag agctcgttga tttagacttt
    35101 aaccgtgtca tctatctagg cgctggtcct ttctttggac ttgctcatga agctcagctc
    35161 aagattttgg aattaactgc tggtcaagtt gcgaccatgt atgaaagccc agttggcttc
    35221 cgtcacggtc caaaatctct tatcaacgac aatacagttg ttttggtctt tggtacaacg
    35281 acagactaca ctcgtaagta cgacttggac ttggttcgtg aagttgctgg tgaccagatt
    35341 gctcgtcgtg ttgtgctttt gagtgatcaa gcttttggtc ttgaaaatgt caaagaagtg
    35401 gtccttggtt gtggcggtgt cttgaatgat atttaccgtg tcttccctta catcgtttat
    35461 gcccaactct ttgctctatt gacttcactc aaggtagaaa ataaaccaga tacaccgtct
    35521 cctacaggta cagtaaaccg tgtagtacaa ggtgtcataa ttcacgaata tcaaaagtaa
    35581 gacagtgttt atgaattctt gacaagagga tttgtaaatt atcagataaa ccatagattg
    35641 tcagtacgct ttctatggtt tgtttgcttg agagaaatag taaaaggaga acagaatgaa
    35701 agcatacaca gagcgtgtat ttggaaatgt tgagggcgag gatgtcttgg cctatcgatt
    35761 tgagacagac ggtggctacc aacttgaggt tatgacttat ggcgcgacca tcttgcgcta
    35821 tgtcgcacct gacaaggctg gaaattttgc caatgttatc ttgggatttg atgactttga
    35881 tagttatgta ggcaatagtc ccaagcatgg agcaagtgta ggtcctgtag cgggtcgtat
    35941 tgcaggtgcg acctttgagc tcaatggtaa gacctatgac cttgaggtta ataatgctag
    36001 caactgtaat cacagtggtt caactggttg ggattccagc ttgtttgaag ttgaagaagt
    36061 aagcgatcat ggcttgactc tctacacaga gcgtacagat gggacaggag ggttccctgg
    36121 aaatctcaag atttggatca gttatcactt ggaagaaact ggtgcctatg aaattagcta
    36181 caaggtaacg accgatcagg atacgctggt caatccaacc aaccacagct atttcaactt
    36241 gtctggtgat ttcacgcaga cgattgaccg tcatgtcttc caactaaaca cagagggcat
    36301 ttactcaatc actcctgacg gtgttcctgc caaaactcca gaagccaacc gtgatgtggt
    36361 caaacacatc tacaatggta ccttgttgaa ggatatcttt gcagaagaag atgagcaaat
    36421 ccagctggca tcaggtttgg atcacccatt tgcccttcct gtaggccatg acaatgctgg
    36481 attcctttat gaccaaaatt caggtcgctt cctgcttttc aagacagaag ctccttgctt
    36541 tgtggtctac acagcaaact ttgtggatga aagtgtcatc ataggaggtc agccaatgct
    36601 acagcacaat gggattgctc ttgaagcgca agctttacca gatgccattc acagtgacct
    36661 taaaggccaa gtcattctta aagctggtca aaccttcacc agtaagacac gttatgaact
    36721 tgttgtgaaa taaaaaagct ggtcaaaaag tctttaaaat taaaataacg catattgtca
    36781 ggtgatgaaa agtttgataa tatgcgtttt attatgaaat gatttacttt atcttatcct
    36841 gaaatggtgt tatttttgag ttatctggct tgactttctt gatggaaatt atataatagt
    36901 tgtaataaca ataattacaa cgagaaaaga ggaccattta tgacctatga atacaagagt
    36961 cacatttatt tggcagagac agttttaaat gtaaaggatt tggccagtca aacagccttt
    37021 tatcagcaag ttatcggttt agaaatctta tctcaaactg agacagagtc cattctaggc
    37081 cttggtggaa aagtcttggt acagctgatt caagcacaag agagcggaga agtgagggaa
    37141 cattatggtc tttaccattt ggccattctc ttgcccacac gcaaggcttt ggctgatgtc
    37201 ttgaaacacc tgacagattt acaaattcct cttgtcggcg gtgcagacca tggttacagt
    37261 gaagctattt acttggaaga tttggaggga aatggcattg aactctatcg agataagcca
    37321 gtttccacat gggatattcg agaagatgga cgcattatcg gagtgacgga ggctcttgcg
    37381 gcgcaggata tttatgagtt gggggaaaga gtagagccct ttatcctggc agaaggtacg
    37441 agaatggggc atattcatct ttccgtcaag gatagtcgaa agtccagcca gttttatcaa
    37501 aaggtgttag ggctagagga taaattcagt gtgcctggcg ctagttggat tgcggctgga
    37561 gattaccatc atcatttagc agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag
    37621 caaggcttac caggtttagc ctactatgtc atcgaagtcg cacataaaga agaactgtta
    37681 acgattgccc agcgagcaca agaagttgac gcaccaatca aatggatgac atcgagccaa
    37741 ttggaaatca cagactcaga tggcatcgtg acctgtattc gtttagcaag gtaaaattag
    37801 gaatttttaa taagttataa gtattgttag tttgcttttt gaacggtctt tggtaacaga
    37861 actgcgtgag ctggatgggc gagaattttg acaaagaagc tgattagaga tataatgaag
    37921 aaaaatcgag caaggaaaaa gaaatgacaa attcaaagta tattacttgt ttgaaacgtt
    37981 cagagggcca gttgtgtggg attcaaaaga tgattgaagg agatcgtgac tgtgctgata
    38041 ttgtgacgca actgacagca gtgagatcta gtgtagagcg cgtgattgag atgataatta
    38101 ccgaaaatct tactgaatgt atcaatcagc cactagatga ttctgaagct caaaaggaac
    38161 gcctagaaaa ggctatccga tacttgatta aacggaaata aatgaatgtt ttgagacgat
    38221 atgtgcaaag gtctattaac tattagaata gtttaatgtg agtcaaaaga agttgtaaaa
    38281 aatctttaaa attaaaaaaa cgcatagtat caggtgttga atgtactgac ccccaaaagt
    38341 tagatttttt ctgtctaact tttggggtgc agttcataag aaccttggta atatgcgttt
    38401 tattatgtag agacttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
    38461 cgtag
//
LOCUS       DAVDFK010000017        38152 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.17, whole genome shotgun sequence.
ACCESSION   DAVDFK010000017 DAVDFK010000000
VERSION     DAVDFK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.17"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..252)
                     /locus_tag="VUR04_001088"
     CDS             complement(<1..252)
                     /locus_tag="VUR04_001088"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HET5340993.1"
                     /translation="MVDLAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTY"
     gene            complement(198..611)
                     /locus_tag="VUR04_001089"
                     /pseudo
     CDS             complement(198..611)
                     /locus_tag="VUR04_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810031.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(612..1037)
                     /locus_tag="VUR04_001090"
     CDS             complement(612..1037)
                     /locus_tag="VUR04_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HET5340994.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            1214..1783
                     /locus_tag="VUR04_001091"
     CDS             1214..1783
                     /locus_tag="VUR04_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5340995.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRVVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            1851..2501
                     /locus_tag="VUR04_001092"
     CDS             1851..2501
                     /locus_tag="VUR04_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HET5340996.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKKEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            2485..4725
                     /locus_tag="VUR04_001093"
     CDS             2485..4725
                     /locus_tag="VUR04_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET5340997.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SFIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLMVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            4867..5091
                     /locus_tag="VUR04_001094"
     CDS             4867..5091
                     /locus_tag="VUR04_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5340998.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYKVGGGWNYARYEVINYYTGSY"
     gene            5123..5716
                     /locus_tag="VUR04_001095"
     CDS             5123..5716
                     /locus_tag="VUR04_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5340999.1"
                     /translation="MLNLTHVTLKTRQVILQDVDFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAAPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVEICDSMVTIHQGQIEEVPL"
     gene            5713..6897
                     /locus_tag="VUR04_001096"
     CDS             5713..6897
                     /locus_tag="VUR04_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341000.1"
                     /translation="MKDISLFLLKKVFKSRLNWIILLLSASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDLQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKDYEFVSNDPTASSELKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAQLYPFSKVTFALSS
                     LGVGMSYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPS
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFN
                     RF"
     misc_feature    7061..7192
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            7208..7738
                     /gene="infC"
                     /locus_tag="VUR04_001097"
     CDS             7208..7738
                     /gene="infC"
                     /locus_tag="VUR04_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET5341001.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            7771..7971
                     /gene="rpmI"
                     /locus_tag="VUR04_001098"
     CDS             7771..7971
                     /gene="rpmI"
                     /locus_tag="VUR04_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET5341002.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            8023..8382
                     /gene="rplT"
                     /locus_tag="VUR04_001099"
     CDS             8023..8382
                     /gene="rplT"
                     /locus_tag="VUR04_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET5341003.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            8440..8820
                     /locus_tag="VUR04_001100"
     CDS             8440..8820
                     /locus_tag="VUR04_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5341004.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            9070..9870
                     /locus_tag="VUR04_001101"
     CDS             9070..9870
                     /locus_tag="VUR04_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET5341005.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYFSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            9881..10819
                     /locus_tag="VUR04_001102"
     CDS             9881..10819
                     /locus_tag="VUR04_001102"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET5341006.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            10861..12762
                     /locus_tag="VUR04_001103"
     CDS             10861..12762
                     /locus_tag="VUR04_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET5341007.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(12823..14478)
                     /gene="pavA"
                     /locus_tag="VUR04_001104"
     CDS             complement(12823..14478)
                     /gene="pavA"
                     /locus_tag="VUR04_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET5341008.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            14583..15080
                     /gene="ybeY"
                     /locus_tag="VUR04_001105"
     CDS             14583..15080
                     /gene="ybeY"
                     /locus_tag="VUR04_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET5341009.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            15061..15456
                     /locus_tag="VUR04_001106"
     CDS             15061..15456
                     /locus_tag="VUR04_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET5341010.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            15473..16372
                     /gene="era"
                     /locus_tag="VUR04_001107"
     CDS             15473..16372
                     /gene="era"
                     /locus_tag="VUR04_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET5341011.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMAERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            16421..17245
                     /gene="mutM"
                     /locus_tag="VUR04_001108"
     CDS             16421..17245
                     /gene="mutM"
                     /locus_tag="VUR04_001108"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET5341012.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            17245..17850
                     /locus_tag="VUR04_001109"
     CDS             17245..17850
                     /locus_tag="VUR04_001109"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET5341013.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            17837..19036
                     /locus_tag="VUR04_001110"
     CDS             17837..19036
                     /locus_tag="VUR04_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET5341014.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            19036..19185
                     /gene="rpmG"
                     /locus_tag="VUR04_001111"
     CDS             19036..19185
                     /gene="rpmG"
                     /locus_tag="VUR04_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5341015.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            19225..19458
                     /gene="secG"
                     /locus_tag="VUR04_001112"
     CDS             19225..19458
                     /gene="secG"
                     /locus_tag="VUR04_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET5341016.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            19560..21914
                     /gene="rnr"
                     /locus_tag="VUR04_001113"
     CDS             19560..21914
                     /gene="rnr"
                     /locus_tag="VUR04_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET5341017.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERIIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            21877..22344
                     /gene="smpB"
                     /locus_tag="VUR04_001114"
     CDS             21877..22344
                     /gene="smpB"
                     /locus_tag="VUR04_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET5341018.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            22360..23220
                     /gene="tehB"
                     /locus_tag="VUR04_001115"
     CDS             22360..23220
                     /gene="tehB"
                     /locus_tag="VUR04_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET5341019.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            23293..24246
                     /gene="coiA"
                     /locus_tag="VUR04_001116"
     CDS             23293..24246
                     /gene="coiA"
                     /locus_tag="VUR04_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET5341020.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLVNKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYKVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            24265..26067
                     /gene="pepF"
                     /locus_tag="VUR04_001117"
     CDS             24265..26067
                     /gene="pepF"
                     /locus_tag="VUR04_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET5341021.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAVLAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            26069..26782
                     /locus_tag="VUR04_001118"
     CDS             26069..26782
                     /locus_tag="VUR04_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET5341022.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            26849..27790
                     /gene="prsA"
                     /locus_tag="VUR04_001119"
     CDS             26849..27790
                     /gene="prsA"
                     /locus_tag="VUR04_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET5341023.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(27909..28250)
                     /locus_tag="VUR04_001120"
                     /pseudo
     CDS             complement(27909..28250)
                     /locus_tag="VUR04_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            28663..28758
                     /locus_tag="VUR04_001121"
                     /pseudo
     CDS             28663..28758
                     /locus_tag="VUR04_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(29011..29631)
                     /locus_tag="VUR04_001122"
     CDS             complement(29011..29631)
                     /locus_tag="VUR04_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5341024.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(29631..30113)
                     /locus_tag="VUR04_001123"
     CDS             complement(29631..30113)
                     /locus_tag="VUR04_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET5341025.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(30113..30955)
                     /locus_tag="VUR04_001124"
     CDS             complement(30113..30955)
                     /locus_tag="VUR04_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET5341026.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSILK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(31050..31850)
                     /locus_tag="VUR04_001125"
     CDS             complement(31050..31850)
                     /locus_tag="VUR04_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET5341027.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMENAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            31994..33373
                     /gene="glmU"
                     /locus_tag="VUR04_001126"
     CDS             31994..33373
                     /gene="glmU"
                     /locus_tag="VUR04_001126"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET5341028.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            33383..33928
                     /locus_tag="VUR04_001127"
     CDS             33383..33928
                     /locus_tag="VUR04_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5341029.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            33940..34254
                     /locus_tag="VUR04_001128"
     CDS             33940..34254
                     /locus_tag="VUR04_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET5341030.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            34271..34963
                     /locus_tag="VUR04_001129"
     CDS             34271..34963
                     /locus_tag="VUR04_001129"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET5341031.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEIV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            35040..35531
                     /gene="rocS"
                     /locus_tag="VUR04_001130"
     CDS             35040..35531
                     /gene="rocS"
                     /locus_tag="VUR04_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET5341032.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            35629..36219
                     /locus_tag="VUR04_001131"
     CDS             35629..36219
                     /locus_tag="VUR04_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET5341033.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVSLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            36228..37991
                     /locus_tag="VUR04_001132"
     CDS             36228..37991
                     /locus_tag="VUR04_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET5341034.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        11590 a         6963 c         8417 g        11182 t
ORIGIN      
        1 ataagtggtc acaccttgac gcaagccttc atcttcagag attgcttgtg cgaatccttt
       61 gccagccaaa gcttcgatat aaggaagagt gacattggtt agggcgatgg ttgaagtgcg
      121 agcaaccgca ccagggatat tggcaacggc atagtggaga acaccgtgtt tttcatagac
      181 gggttcatcg tgcgttgtca cacggtcagc tgtttcgata aggccacctt ggtcaacagc
      241 aaggtcaacg atacagagcc tggacgcatt tgtttgacca tctcatctgt caccaattcc
      301 ggtgcttttg caccagggat gagaatggct ccaatcacca catcagcatc tctcacactt
      361 gcttcaatgt tgaatgaatt agatataaga gtttaaattt gacttccaaa gacttctttt
      421 agaactgaga gacgcttggc actaatatct aaaatagtca cttgagcacc aagaccaagg
      481 gcgatgcggg cagcatgtgt accgacgaca ccatcaccga tgatagttac ttttcctttt
      541 ggaacacctg gtacaccacc aggtagaaca ccagagccac cagcttgctt agtaaggaag
      601 tgagctccga tttaaacagc catacgacct gcaacctcac tcataggaac gaggagcggt
      661 agttgtcctt gattgtcacg aacagtttca taggcaattc ctgttgtttt tgctgctaac
      721 atagcatctg ctaattctgg agcagcggcc atgtgcaagt aggtgaagag aagaagatcg
      781 tcgcgcaagt aaccgtattc agaacttaaa ggttctttta ctttcacaac caactctgct
      841 gcccaagctt caccagcagt agcgacaatc tcagctcctt gcttttgata gtcagcatca
      901 gtaaagccag aaccgagacc agcatttgtt tcgataagga cacgatgacc acgactaact
      961 aagctatgaa cacctgcagg tgtgagggcg acacggtttt cgttattttt aatttctttt
     1021 gggattccga ttaacattga gataacctac ctttcaattg acggtcttgt tttggttgtc
     1081 acattccagt tcataaatca aaaatgtgac ggtttcattg tatatgaaac cgcttcaaaa
     1141 atcaagaaaa acttgtcatc caaatttttt atgctagact agtgaaaatc aagctttgat
     1201 tggttggaaa agtatggaat caatttttgt aaaacttgcc cagtatccgt ctatagaaac
     1261 ggagcgttta ttgcttagac ctgtaacttt ggatgatgcg gaagcaatgt ttgactatgc
     1321 ctcggacaag ggtaatacac gttacacttt tccaaccaat caaagtttgg aagaaaccaa
     1381 gaataacatt gctcagttct atttggctaa tcccttggga cgttggggaa tagaactaaa
     1441 aagcaatggt cagtttattg gaaccattga cttgcacaag attgattctg ttcttaagaa
     1501 ggcagctatt ggctacatta tcaataaaaa gtattggaat caaggattaa cgacagaagc
     1561 caatcgtgtt gtgattgagc tagcttttga gaagataggg atgaataagt tgactgccct
     1621 tcacgataag gacaatcctg cgtcaggaaa ggtcatggag aaatcaggca tgcgtttttc
     1681 ccatgcagaa ccatatgctt gtatggacca gcatgaaaaa ggccgaatcg tgacaagagt
     1741 tcattatgtc ttgaccaagg aagactattt tgcaaataaa taagcagttg aaaagaaatt
     1801 tttcgactgt tttttcttcc tcttacgaat aatctaagag aggagaaaat atggaagcaa
     1861 ttatcgagaa aatcaaagag tataaaatca tcgtcatctg tactggtctg ggcttgcttg
     1921 taggaggatt tttcctgcta aaaccagctc cacaaacacc tgtcaaagag acgaatttgc
     1981 aggctgaagt cgcagctgtt tccaaggatt tggtatccga aaaggaagtg aacaaggaag
     2041 aaaagaaaga accccttgaa caagatctaa tcacagtaga tgtcaaaggt gctgtcaaat
     2101 cgccagggat ttatgacttg cctgtaggta gtcgagtcaa tgatgctgtt cagaaggctg
     2161 gtggcttgac agagcaagca gacagcaagt cgctcaatct agctcagaaa gttagtgatg
     2221 aggctctggt ttacgttcct actaagggag aagaagcagt tagccaacag actggtttgg
     2281 ggacagcttc ttcaataagc aaggaaaaga aggtcaatct caacaaggcc agtctggaag
     2341 aactcaagca ggtcaaggga ctgggaggaa aacgagctca ggacattatc gaccatcgtg
     2401 aggcaaatgg caagttcaag tcagtagacg agctcaagaa ggtctctggc attggtggca
     2461 aaacaataga aaagcttaaa gactatgtta cagtggatta agaatttctc tattccccta
     2521 atttacctga gttttctgtt actttggctt tattacgcta ttttctcagc atcttatctt
     2581 gctttgttgg gctttgtttt tctgctagtc tgtctcttta tccaatttcc gtggaaatct
     2641 gctggtaaag ttctaataat ttgcggaatc tttggatttt ggtttgtttt tcaaaattgg
     2701 caacagagtc aagcgagtca aaatctggcg gattctgttg aaagggtacg gattttgcct
     2761 gatactatta aggtcaatgg tgatagtcta tcctttcgtg gcaagtctaa cggtcgtgct
     2821 ttccaagtct attataaact ccagtccgag gaggagaaag aagcctttca agctttaacc
     2881 gacctgcatg agataggact agaagggaag ctttcggagc cagaagggca gagaaatttt
     2941 ggtggcttta attaccaagc ctatctgaag actcagggaa tttaccagac tctcaatatc
     3001 aaaacaatcc agtcacttca aaagattggc agttgggata taggagaaaa cttgtccagt
     3061 ttacgtcgaa aggctgtggt ttggattaag acgcactttc cagaccctat gcgcaattac
     3121 atgacaggac tcttgctggg acatctggac accgactttg aggagatgaa tgagctttat
     3181 tccagtctag gaattatcca cctctttgcc ctatctggta tgcaggtagg ttttttcatg
     3241 aatggattta agaaacttct cttgcgattg ggcttgaccc aagaaaagtt gaaatggctg
     3301 acttatccct tttcctttat ctatgcggga ctaactggat tttcagcatc ggttattcgc
     3361 agtctcttgc aaaagctact ggctcaacat ggggttaagg gcttggataa ttttgccttg
     3421 acggtgcttg tcctctttat tgtcatgcca aactttttct tgacagcagg aggagtcttg
     3481 tcctgcgctt atgcttttat cctgaccatg accagcaaag aaggggaggg gctcaaggct
     3541 gttactagtg aaagtctagt catctccttg ggcatattgc ccattctatc cttctatttt
     3601 gcggaatttc aaccttggtc tatccttttg acctttgtct tttcctttct atttgacttg
     3661 accttcttac cgctcttgtc tattttattt gtcctttcct ttctctatcc agtcattcag
     3721 ctgaacttta tctttgaatg gttggagggc attattcgct tggtgtcaca ggtgacaagt
     3781 agacctctgg tctttggaca acccaatgca tggtttttaa tcctattgtt aatttccttg
     3841 gctttggtct atgatttgag aaaaaacatt aaaaagctaa tggtattgtg cttattgatt
     3901 acagggctct ttctcctgac caagcatcca ctggaaaatg aaatcaccat gctggatgtg
     3961 gggcaaggag aaagtatttt cctacgggat gtaactggga aaaccattct catagatgta
     4021 ggtggtaagg cagaatctta taagaaaatc gaaaaatggc aagaaaagat gacgaccagc
     4081 aatgcccagc gaaccttgat tccctatctc aaaagtcgag gagtagctaa gattgaccag
     4141 ctaattttga ctaacacgga caaggagcat gttggagatt tgtcagagat gaccaaggct
     4201 ttccatgtag gggagattct agtatcaaaa gacagtctga aacagaagga atttgtggca
     4261 gaactacagg cgactcaaac aaaggtgcgt agtatgacag taggggagaa cttgcccatt
     4321 tttggaagtc agttagaagt tctatctcca aggaaaatgg gagatggagg acacgatgat
     4381 accctagttc tgtatgggaa attcttggat aagcaatttc tcttcacggg aaatttggag
     4441 gagaaaggag agaaggactt gctgaagcac tatccagact tgaaagtaaa tgttttgaaa
     4501 gctagccaac atggcaataa aaaatcatca agtccagcct ttctagaaaa actcaaacca
     4561 gagcttactc ttatctcagt tggaaagagc aatcgaatga aactccccca tcaggaaaca
     4621 ttgacacgac tggaaggtat caatagcaaa gtttatcgaa ctgaccagca aggagctata
     4681 cggtttaaag gttggaatag ttggaaaatc gaaagtgttc gataggaaag ataaatgttg
     4741 tagattagtg aaataaacta aaaatttgtt gcataataat gataaaaatg gtataataaa
     4801 aacgtattca atactgagga tataaaatca ttaaaaatta gcaaaaatcg tttaattagt
     4861 tagtttatga ttattggtct ttttcagtcc agtatatctg ctgtgacagt cactaaaagt
     4921 tacaagtatg attggaatac ggtttgggaa tatagtacca actatcacga ccatcagtat
     4981 gcttggattc cgtcatggtc tcgttatgac agctattctg agtataaagt tggcggaggc
     5041 tggaactacg ctcgttatga ggtcataaac tactatactg gaagttatta atccttaaag
     5101 agtgagaaaa ggagggctgg atatgttaaa tcttactcat gttaccttaa aaacgcgaca
     5161 agtcatcttg caagatgttg atttcacctt taaaaagggt aggatttatg gccttcttgc
     5221 tatcaatggc tcgggaaaga cgacactatt ccgagctatg agcaagttgc ttccccttag
     5281 tagtggacat atcgcagccc ctccttcttt gttttattat gagagcgttg aatggctgga
     5341 tggaaactta agtgggatgg actaccttcg tctcataaaa aacatctgga agtcagacct
     5401 aaacttgagg gatgaaatcg cctactggga aatggctgac tatatcagtc ttcccatccg
     5461 caagtattcc ttagggatga agcaacgctt ggtgattgct atgtattttc tcagtcaggc
     5521 caaatgctgg ctcatggatg agattacaaa tggcttagat gagtattatc gacagaagtt
     5581 ttttgataga ctagcacaaa tcgatagaca agaacagctg gttcttttga gttcccacta
     5641 caaagaggag ttagtggaga tttgcgatag catggtaacc attcatcagg ggcagataga
     5701 agaggttccg ttatgaaaga tattagccta tttttgttaa agaaagtttt caaaagtcgt
     5761 ttaaactgga ttatcttact tttatctgca tctgtactcg gtgttacctt ttatttaaat
     5821 agtcagactg caaactcaca cagcttggag agcaggttgg aaagtcgcat tgcagccaac
     5881 gagagggcta tcaatgaaaa tgaagagaaa ctctcccaaa tgtctgatac cagctcggag
     5941 gaataccagt ttgctaaaaa taatttagac ttgcaaaaaa atcttttgac gcgaaagaca
     6001 gaaattctaa ctttactaaa agaagggcgc tggaaagaag cctactattt gcagtggcaa
     6061 gatgaagaga aggattatga atttgtatca aatgacccga ctgctagctc tgaattaaaa
     6121 atgggggttg accgcgaacg gaagatttat caagccctgt atcccttgaa cataaaagca
     6181 catactttgg agtttccgac ccacgggatt gatcagattg tctggatttt agaggttatc
     6241 atcccaagct tgtttgtggt tgctattatt tttatgctaa cacaactatt tgcagaaaga
     6301 tatcaaaatc atctcgatac agctcagtta tatccttttt caaaagtgac atttgccctg
     6361 tcctctcttg gagttgggat gagttatgta accgtgctgt ttatcggaat ctgtggattt
     6421 tctttcctag tgggaagtct gataagtggt tttggacagt tagattatcc ctacccgatt
     6481 tatagcttag tgaatcaaga ggtaactatt ggaaagatgc aggatgtatt atttcctagc
     6541 ttgctcttag ctttcttagc ctttatcgtc attgtggaag ttgtgtattt gattgcttac
     6601 tttttcaagc aaaaaatgcc tgtcctcttt ctttcactca ttgggattgt tggcttattg
     6661 tttggcatcc aaaccattca gcctcttcaa aagattgcac atctgattcc ctttacttac
     6721 ttgcgttcag tggagatttt atctggaaga ttacctaagc agattgataa tgtcgatcta
     6781 aattggagca tgggaatggt cttacttcct tgcctgatta tctttttgct attgggaatt
     6841 ctatttattg aaagatgggg aagttcacag aaaaaagaat tttttaatag attctagctt
     6901 tcctataggt agggaaaata agtaaaaact aacatagaga gggaatcaac ttgattctct
     6961 ctttttgatt cgaaaaccaa accaaaatac aaacacaaac ttttcaaaaa ataacttttt
     7021 atcttgacaa gagctagaaa acttggtatc atataaaagt tgagaaaagc agaagtgaga
     7081 gcttctcgcc ttgtgacatt aagttgcctg gccctacgga tgaaaagttt cgaagaaacg
     7141 ctatcataac gtgcgggctt gtatatttac gagtccgcta ttgtttttct ctaataaaac
     7201 aaaagaggtg aaaaccatag caaagcaaga cttattcatc aatgatgaga ttcgtgtacg
     7261 tgaagttcgc ttgattggtc ttgagggaga acagctaggc atcaagccac tcagtgaagc
     7321 gcaagctttg gctgataacg ctaatgttga cctagtattg attcaacccc aagccaaacc
     7381 gcctgttgca aaaattatgg actacggtaa gttcaaattt gagtaccaga agaagcaaaa
     7441 agaacaacgt aaaaaacaaa gcgttgttac tgtgaaagaa gttcgtctaa gtccaacaat
     7501 tgacaagggt gactttgata caaaacttcg caatgcacgt aagttccttg aaaaaggaaa
     7561 taaagttaag gtatctattc gctttaaggg tcgtatgatt acccataaag agattggtgc
     7621 aaaagtttta gccgagtttg ctgaagcaac tcaagatatt gccatcatcg aacaacgtgc
     7681 taaaatggat ggacgtcaaa tgttcatgca attggcgcca gcgactgaca aaaaataatt
     7741 gtcagaaagt taaataaagg agaaaaaatc atgccaaaac aaaaaacaca ccgcgcatca
     7801 gctaaacgtt tcaaacgtac aggttctggt ggacttaaac gtttccgtgc ttacacttct
     7861 caccgtttcc acggaaaaac taagaaacaa cgtcgtcatc ttcgtaaagc atctatggtg
     7921 cattcaggag attacaaacg tatcaaagca atgcttactc gcttgaaata atagcttgac
     7981 tgtaagtaaa caattctagg aaatatttgg aggaaataaa acatggcacg tgttaaaggt
     8041 ggcgttgtat cacgcaaacg tcgtaaacgt attcttaaat tagcaaaagg ttactatgga
     8101 gctaaacaca tcttgttccg tactgcaaaa gaacaagtaa tgaactctta ctactatgca
     8161 taccgtgacc gtcgtcagaa aaaacgtgac ttccgcaaat tgtggattac tcgtatcaat
     8221 gcggcagctc gtatgaacgg actttcatac tcacaattga tgcatggttt gaaattggct
     8281 gagatcgaag ttaaccgtaa aatgcttgct gacttggctg ttaacgatgc agtagctttc
     8341 acagctcttg cagatgcagc taaagcaaaa cttggtaaat aacaactgat gagactggaa
     8401 caggattgtc cagtcttttt aaaaataaag gagaaagata tggcttcaaa aatgctacac
     8461 acttgcttac gagtagaaaa tcttgaaaaa tcaatcgcat tttatcaaga tgcttttggt
     8521 tttaaagaat tgcgtcgcag agattttcca gaccatgcct tcacgattgt ctatctaggt
     8581 cttgagggtg atgattatga gttggagttg acttataact acgatcacgg tccgtatgtg
     8641 gttggtgatg ggtttgccca tatcgccctc agtacacctg atcttgaggc acttcatcaa
     8701 gaacacagtg caaaaggcta tgaagtgact gagccaaatg gtctaccagg aactacacca
     8761 aactattact ttgttaaaga ccctgatgga tataaggtcg aagtcattcg tgaaaaataa
     8821 tttcgtgcaa gttaagtaga atattcgttt tctacttgac tttttttagc tgaaagagta
     8881 tactaataaa aattcaacct ttaaggggag tccagagaga ctcacaaggt gtcagataaa
     8941 agaatagtgc aattttctag aggagacctt ttgagtgtgc tctcttgtgt tgtacgattt
     9001 taactgaggc cttgcactag caaggtcttt tctttatctg gtccccttaa aatttaagga
     9061 ggaaaagtta tgaatctcac atgtaagaag cgtttgggtg tcattcggtt ggaaaccatg
     9121 aaggtggttg cacaagagga aatcgcgcca gcaatctttg aattagtcct agaaggagaa
     9181 atggttgaag ccatgcgagc aggccaattt cttcatctgc gtgtaccaga cgatgcccat
     9241 ctcttacgtc gtcctatttc aatttcgtct attgacaagg caaacaagca gtgtcacctc
     9301 atttatcgga ttgagggagc tgggactgca attttttcaa ccttaagtca gggagacact
     9361 cttgatgtga tggggcctca gggaaatggt tttgacttgt ctgaccttga tgagcagaat
     9421 caggttctcc ttgttggtgg tgggattggt gttccaccct tgcttgaggt ggccaaggaa
     9481 ttgcatgaac gtggagtgaa agtagtgaca gtcctcggtt ttgctaataa ggatgctgtt
     9541 attttgaaaa cggaattggc tcagtatggt caggtctttg taacgacaga tgatggttct
     9601 tatggcatca agggaaatgt ttccgttgtt atcaatgatt tagatagtca gtttgatgct
     9661 gtttactcgt gtggggctcc aggaatgatg aagtatatca atcaaacctt tgatgatcac
     9721 ccaagagcct atttctctct ggaatctcgt atggcttgtg ggatgggagc ttgctatgcc
     9781 tgtgttctaa aagtaccaga aagcgagacg gtcagccaac gcgtctgtga agatggtcct
     9841 gttttccgca caggaacagt tgtattataa ggagaaaatt atgactacaa atcgattaca
     9901 agtgtctcta cctggtttgg atttgaaaaa tccgattatt ccagcatcag gctgttttgg
     9961 ctttggacaa gagtatgcca agtactatga tttagacctt ttaggttcta ttatgatcaa
    10021 ggcgacaacc cttgaaccac gttttgggaa tccaactcca agagtggcag agacgcctgc
    10081 tggtatgctc aatgcaattg gcttgcaaaa tcctggttta gaggttgttt tggctgaaaa
    10141 gctaccttgg ctggaaagag aatatccaaa tcttcctatt attgccaatg tagctggttt
    10201 ttcaaaacaa gagtatgcag ctgtttctca tgggatttcc aaggcaacta atgtaaaagc
    10261 tatcgagctc aatatttctt gtcccaatgt tgaccactgt aatcatggac ttttgattgg
    10321 tcaagatcca gatttggctt atgatgtggt gaaagcagct gtggaagcct cagaagtgcc
    10381 agtttatgtc aaattaaccc cgagtgtgac cgatatcgtt actgtcgcaa aagctgcaga
    10441 agatgcggga gcaagtggct tgaccatgat caatactctg gttggaatgc gctttgacct
    10501 caaaaccaga aaaccaatct tggccaatgg aacaggtgga atgtcaggtc cagcagtctt
    10561 tccagtagcc ctcaaactca tccgccaagt agcccaaaca acagacctgc ctatcattgg
    10621 aatgggggga gtggattcgg ctgaagctgc cctagaaatg tatctggctg gggcatctgc
    10681 tatcggagtt ggaacagcta actttaccaa tccttatgcc tgccctgaca tcatcgaaaa
    10741 tttaccaaaa gtcatggata aatacggtat tagcagtctg gaagaactcc gtcaggaagt
    10801 aaaagagtct ctgaggtaaa ctgcaatcaa tctgttcttg attttttatt agtttgtaat
    10861 atgaatttag gagaattttg gtacaataaa ataaataaga acagaggaag aaggttaatg
    10921 aagaaagtaa gatttatttt tttagctctg ctatttttct tagctagtcc agagggtgca
    10981 atggctagtg atggtacttg gcaaggaaaa cagtatctga aagaagatgg cagtcaagca
    11041 gcgaatgagt gggtttttga tactcattat caatcttggt tctatataaa agcagatgct
    11101 aactatgctg aaaatgaatg gctaaagcaa ggtgacgact atttttacct caaatctggt
    11161 ggctatatgg ccaaatcaga atgggtagaa gacaagggag ccttttatta tcttgaccaa
    11221 gatggaaaga tgaaaagaaa tgcttgggta ggaacttcct atgttggtgc aacaggtgcc
    11281 aaagtaatag aagactgggt ctatgattct caatacgatg cttggtttta tatcaaagca
    11341 gatggacagc acgcagagaa agaatggctc caaattaaag ggaaggacta ttatttcaaa
    11401 tccggtggtt atctactgac aagtcagtgg attaatcaag cttatgtgaa tgctagtggt
    11461 gccaaagtac agcaaggttg gctttttgac aaacaatacc aatcttggtt ttacatcaaa
    11521 gaaaatggaa actatgctga taaagaatgg attttcgaga atggtcacta ttattatcta
    11581 aaatccggtg gctacatggc agccaatgaa tggatttggg ataaggaatc ttggttttac
    11641 ctcaagtttg atggcaaaat ggctgaaaaa gaatgggtct acgattctca tagtcaagcc
    11701 tggtactact tcaaatccgg tggttacatg acagccaatg aatggatttg ggataaggaa
    11761 tcttggtttt acctcaaatc tgatgggaaa atagctgaaa aagaatgggt ctacgattct
    11821 catagtcaag cttggtacta cttcaaatct ggtggctaca tggcgaaaaa tgagacagta
    11881 gatggttatc agcttggaag cgatggtaaa tggcttggag gaaaagctac aaatgaaaat
    11941 gctgcttact atcaagtagt gcctgttaca gccaatgttt atgattcaga tggtgaaaag
    12001 ctttcctata tatcgcaagg tagtgtcgta tggctagata aggatagaaa aagtgatgac
    12061 aagcgcttgg ctattactat ttctggtttg tcaggctata tgaaaacaga agatttacaa
    12121 gcgctagatg ctagtaagga ctttatccct tattatgaga gtgatggcca ccgtttttat
    12181 cactatgtgg ctcagaatgc tagtatccca gtagcttctc atctttctga tatggaagta
    12241 ggcaagaaat attattcggc agatggcctg cattttgatg gttttaagct tgagaatccc
    12301 ttccttttca aagatttaac agaggctaca aactacagtg ctgaagaatt ggataaggta
    12361 tttagtttgc taaacattaa caatagcctt ttggagaaca agggcgctac ttttaaggaa
    12421 gccgaagaac attaccatat caatgctctt tatctccttg cccatagtgc cctagaaagt
    12481 aactggggaa gaagtaaaat tgccaaagat aagaataatt tctttggcat tacagcctat
    12541 gatacgaccc cttacctttc tgccaagaca tttgatgatg tggataaggg aattttaggt
    12601 gcaaccaagt ggattaagga aaattatatc gataggggaa gaactttcct tggaaacaag
    12661 gcttctggta tgaatgtgga atatgcttca gacccttatt ggggcgaaaa aattgctagt
    12721 gtgatgatga aaatcaatga gaagctaggt ggcaaagatt agtactataa gtgaatatga
    12781 tttgagtgaa tagtaagtta aaaatcctga tttcaagtaa aatcaggatt ttttcatgga
    12841 tgcaattttt ttggagtctg gtgtgacgcg gagggtcttt tgtcctgtgt aagtgacaaa
    12901 gccgggtttt ccaccagttg gtttattgag ttttttgact tcaatcatat ctacctgcac
    12961 cagattcgac aggcgccctt gagagaagta ggcagctaac tctgctgcgt ctgtcttgac
    13021 tgcatcagat gggtcaagat ttcctgagat gacaacatgg cttccaggaa tgtccttagc
    13081 atggaaccaa agttcctcct tgcgggccat tttaaaggtc aattcctcat tttgaagatt
    13141 gtttcgtccg acatagatga tggttttgcc atcgcttgct agatattgtt ctagtttttt
    13201 gcgtttctgg attttctccc gttgtcttct gcggataaaa cctgtttgaa tcaattcttc
    13261 acggatttca gcgatttctt ccagtccagc ttggttgagg acggtttcta cactttccag
    13321 atagagaata gtggctttgg tttcttcaat caaatcagtc aagtatttga cagcttcttt
    13381 gagtttctga taccgtttaa aatagcgttg ggcattctgg ttgggagtca gagccttatc
    13441 aagcgcaatc atgataggtt ggttggtata gtagttgtct aggataacct ggtcttggtc
    13501 gttaggcact tggtgtagga aggttgtcag caattctcct ttttgacgaa attcttcagc
    13561 gttgtctgtc gccagtaact ctttttcctg ttttttgagt ttgtgtcggt ttttctgaag
    13621 ttcattttca acacgacgaa tcagttcact ggcctgctgt ttgacgcggt cgcgctcagc
    13681 cttatcctta tagtaggtgt ccaacaaatc agaaagattt gcaaaaggct ctcccacctg
    13741 atttgcaaaa ggaactggac tgaaggaagt ctcagtcaag catggcttgg tttcttgatt
    13801 gaaaaaattt cggaaagcgg aaagtttttc actaaccagt atcctttcca attcatttgc
    13861 cgtatcgcgt cccagacctt gaaagaggct ttgaagattt tttgctgtta gttcttgggt
    13921 ttgcaggatt tcaaagagct tttcatcttt gatagtaaaa ggattgagag attctgtact
    13981 tggcggagcg atataggtcg atcctggaag taaggtgcgg tagctatttt gtgaaaaacc
    14041 gacgtgtttg ataacttcga ggattttatg actgctttta tcgaccagta gaatattact
    14101 gtgtttcccc ataatttcaa taatcaaggt agcctggata tggtctccaa tctcgttttt
    14161 attggaaact gtaatttcca caatacggtc attttccact tgctcaatcg actcaatcag
    14221 ggccccctgc aaatactttc tcaaaaccat gataaaggta gaaggttggg ctggattttc
    14281 aaaagtcgtt tgggtcagct gaatgcgtcc aaaaactgga tgggcagaaa ggagcaggcg
    14341 atggctttgg cgattgctgc ggatttgcaa gaccaactct tgttcaaaag gctgattgat
    14401 tttctggatg cgaccattca ctaattcgct tcgcaattcc tcaactatgt ggtgtaaaaa
    14461 aaatccgtca aatgacatcg ttctctcctt gtgattgtat tccatagtat tatatcaaaa
    14521 aggtagaata aaatcatgga aatgtggtat aataaagcca agtaaagaga aacgagaagc
    14581 acatgtatat tgaaatggta gatgaaactg gtcaagtttc aaaagaaatg ttgcaacaaa
    14641 cccaagaaat tttggaattt gcagcccaaa aattaggaaa agaagacaag gagatggcag
    14701 tcacttttgt gaccaatgag cgtagtcatg aacttaatct ggagtaccgt gacaccgacc
    14761 gtccgacaga tgtcatcagc cttgagtata aaccagaatt ggaaattgcc tttgacgaag
    14821 aggatttgct tgaaaatcca gaattggcag agatgatgtc tgagtttgat gcctatattg
    14881 gggaattgtt catctctatc gataaggctc atgagcaggc cgaagaatat ggtcacagct
    14941 ttgagcgtga gatgggcttc ttggcagtac acggcttttt acatattaac ggctatgatc
    15001 actacactcc agaagaagaa gcggagatgt tcggtttaca agaagaaatt ttgacagcct
    15061 atggactcac aagacaataa acgaaaatgg aaaaatcgtg acctgatatc cagtttagaa
    15121 tttgccatca cagggatttt tactgctatc aaggaagaac gaaatatgcg aaaacatgca
    15181 gtgacggctc tagtggttat ccttgcaggt tttggttttc aggtgtcacg aatcgaatgg
    15241 ctctttctcc tattgagcat tttcttggta gtagcctttg aaattatcaa ctctgctatt
    15301 gaaaatatgg tggatttggc cagtcactat cacttttcca tgctggctaa aaatgccaag
    15361 gatatggcgg ctggtgcggt attagtggtt tctcttttcg cagccttaac aggcgcattg
    15421 atttttctcc cgcgaatctg ggatttatta ttttaaacag taagaggaaa ttatgacatt
    15481 taaatcaggc tttgtagcca ttttaggacg tcctaacgtt gggaagtcaa cctttttaaa
    15541 tcacgtcatg gggcaaaaaa ttgccatcat gagtgacaag gcgcagacaa cgcgcaacaa
    15601 aatcatggga atttacacga ctgataagga gcaaattgtc tttatcgaca caccagggat
    15661 tcacaaacct aaaacagctc tcggagattt catggttgag tctgcctaca gtacccttcg
    15721 cgaagtggac accgttcttt tcatggtgcc tgctgatgaa gcgcgtggta agggggacga
    15781 tatgattatc gagcgtctca aggctgccaa ggttcctgtg attttggtgg tgaataaaat
    15841 cgataaggtc catccagacc agctcttgtc tcagattgat gacttccgta atcaaatgga
    15901 ctttaaggaa attgttccaa tctcagccct tcagggaaat aacgtgtctc gtctagtgga
    15961 tattttgagt gaaaatctgg atgaaggttt ccaatatttc ccgtctgatc aaatcacaga
    16021 ccatccagaa cgtttcttag tttcagaaat ggttcgcgag aaagtcttgc acctaactcg
    16081 tgaagagatt ccgcattctg tagcagtagt tgttgactct atgaaacgag acgaagagac
    16141 agacaaggtt cacatccgtg caaccatcat ggccgagcgc gatagccaaa aagggattat
    16201 catcggtaaa ggtggcgcta tgcttaagaa aatcggtagc atggcccgtc gtgatatcga
    16261 actcatgcta ggagacaagg tcttcctaga aacctgggtc aaggtcaaga aaaactggcg
    16321 cgataaaaag ctagatttgg ctgactttgg ctataatgaa agagaatact aagtagaggt
    16381 aggctcatgc ctgcttcttg tttttacaga aggaggactt atgcctgaat tacctgaggt
    16441 tgaaaccgtt tgtcgtggct tagaaaaatt gattatagga aagaagattt cgagtataga
    16501 aattcgctac cccaagatga ttaagacgga tttggaagag tttcaaaggg aattgcctag
    16561 tcagattatc gagtcaatgg gacgtcgtgg aaaatatttg cttttttatc tgacagacaa
    16621 ggtcttgatt tcccatttgc ggatggaggg caagtatttt tactatccag accaaggacc
    16681 tgaacgcaag catgcccatg ttttctttca ttttgaagat ggtggcacgc ttgtttatga
    16741 ggatgttcgc aagtttggaa ccatggaact cttggtgcct gaccttttag acgcctactt
    16801 tatttctaaa aaattaggtc ctgaaccaag cgaacaagac tttgatttac aggtctttca
    16861 atctgccctt gccaagtcca aaaagcctat caaatcccat ctcctagacc agaccttggt
    16921 agctggactt ggcaatatct atgtggatga ggttctctgg cgagctcagg ttcatccagc
    16981 tagaccttcc cagactttga cagcagaaga agcgactgcc attcatgacc agaccattgc
    17041 tgttttgggc caggctgttg aaaaaggtgg ctccaccatt cgaacttata ccaatgcctt
    17101 tggggaagat ggaagcatgc aggactttca tcaggtctat gataagactg gtcaagaatg
    17161 tgtacgctgt ggtaccatca ttgagaaaat tcaactaggc ggacgtggaa cccacttttg
    17221 tccaaactgt caaaggaggg actgatggga aaaatcatcg gaatcactgg gggaattgcc
    17281 tcaggtaagt caactgtgac aaattttcta agacagcaag gctttcaagc agtggatgcc
    17341 gacgcagtcg tccaccaact acagaaacct ggtggtcgtc tgtttgaggc tctagtacag
    17401 cactttgggc aagaaatcat tcttgaaaac ggagaactca atcgccctct cctagctagt
    17461 ctcatctttt caaatcctga agagcaaaaa tggtctaatc aaattcaagg ggagattatc
    17521 cgtgaggaac tggctacttt gagagaacag ttggctcaga cagaagagat tttcttcatg
    17581 gatattcccc tactttttga gcaggactac agcgattggt ttgctgagac ttggttggtc
    17641 tatgtggacc gagatgccca agtagaacgc ttaatgaaaa gggaccagtt gtccaaagat
    17701 gaagctgagt ctcgtctggc agcccagtgg cctttagaaa aaaagaaaga tttggccagc
    17761 caggttcttg ataataatgg caatcagaac cagcttctta atcaagtgca tatccttctt
    17821 gagggaggta ggcaagatga cagagattaa ctggaaggat aatctgcgta ttgcctggtt
    17881 tggtaatttt ctgacaggag ccagtatttc tttggttgta ccttttatgc ccatcttcgt
    17941 ggaaaatcta ggtgtaggga gtcagcaagt cgctttttat gcaggcttag caatttctgt
    18001 ctctgctatt tccgcggcgc tcttttctcc tatttggggt attcttgctg acaaatacgg
    18061 ccgaaaaccc atgatgattc gggcaggtct tgctatgact atcactatgg gaggcttggc
    18121 ctttgtccca aatatctatt ggttaatctt tcttcgttta ctaaacggtg tatttgcagg
    18181 ttttgttcct aatgcaacgg cactgatagc cagtcaggtt ccaaaggaga aatcaggctc
    18241 tgccttaggt actttgtcta caggcgtagt tgcaggtact ctaactggtc cctttattgg
    18301 tggctttatc gcagaattat ttggcattcg tacagttttc ttactggttg gtagttttct
    18361 atttttagct gctattttga ctatttgctt tatcaaggaa gattttcaac cagtagccaa
    18421 ggaaaaggct attccaacaa aggaattatt tacctcggtt aaatatccct atcttttgct
    18481 caatctcttt ttaaccagtt ttgtcatcca attttcagct caatcgatcg gccctatttt
    18541 ggctctttat gtacgcgact tagggcagac agagaatctt ctttttgtct ctggtttgat
    18601 tgtgtccagt atgggctttt ccagtatgat gagtgcagga gtcatgggca agctaggtga
    18661 caaggtgggc aatcatcgtc tcttggttgt cgcccagttt tattcagtca tcatctatct
    18721 cctctgtgcc aatgcctcta gcccccttca actaggactc tatcgtttcc tctttggctt
    18781 gggaaccggt gccttgattc ccggggttaa tgccctactc agcaaaatga ctcccaaagc
    18841 cggcatttcg agggtctttg ccttcaatca ggtattcttt tatctgggag gtgttgttgg
    18901 tcccatggca ggttctgcag tagcaggtca atttggctac catgctgtct tttatgcgac
    18961 aagcctttgt gttgccttta gttgtctctt taacctgatt caatttcgaa cattattaaa
    19021 agtaaaggaa atctagtgcg agtaaaaatt aatctcaaat gctcctcttg tgacagtatc
    19081 aattacctaa ccagtaaaaa ttcaaaaacc catccagaca agattgaggt tttaaagtat
    19141 tgtcccaagg aaagaaaagt aaccctacat cttgaatcta agtagatttt atggtaaaat
    19201 aatagggatt ttaaggagtt tgatatgtat aacctattat taaccatttt attagtatta
    19261 tctgttgtga ttgtgattgc aattttcatg caaccaacca aaaaccaatc cagcaatgta
    19321 tttgatgcca gttcaggtga tttgtttgaa cgcagtaaag ctcgcggttt tgaagctgta
    19381 atgcagcgtt tgacagggat tttagtcttt ttctggctag ccattgcctt agcattgacg
    19441 gtattatcaa gtagataaga aaataatggg caggactagg tctttgcctc tttttatttt
    19501 taaaggatgt ttgagaaggt tttacagtaa aagaaaatta aaaaatctag aaagaaaata
    19561 tgaaagatag aataaaagaa tatttacaag acaagggaaa ggtgactgtt aatgatttgg
    19621 ctcaggcttt gggaaaagac agttccaagg attttcgtga gttgattaaa accttgtcct
    19681 taatggaaag aaagcaccaa attcgttttg aagaagatgg tagtctgaca ttagaaatta
    19741 agaaaaaaca tgagattacc ctcaagggga tttttcatgc ccataaaaat ggctttggct
    19801 ttgttagtct ggaaggcgag gaggacgacc tttttgtagg gaaaaatgat gtcaactatg
    19861 ctattgatgg tgataccgtc gaggtagtga ttaagaaagt cgctgaccgc aataagggaa
    19921 cagcagcaga agccaaaatt attgatatcc tagaacacag tttgacaaca gttgtcgggc
    19981 aaatcgttct ggatcaggaa aagcctaagt atgctggcta tattcgttca aaaaatcaga
    20041 aaatcagtca accgatttat gttaagaaac cagccctaaa gttagaagga acagaagttc
    20101 tcaaggtctt tatcgataaa tacccaagca agaaacatga tttctttgtc gcgagtgttc
    20161 tcgatgtggt gggacactca acggatgtcg gaattgatgt tcttgaggtt ttggaatcaa
    20221 tggacattgt atccgagttt ccagaagctg ttgttaagga agcagaaagt gtgcctgatg
    20281 ctccgtctca aaaggatatg gaaggtcgtc tggatctaag agatgaaatt acctttacca
    20341 ttgacggtgc ggatgccaag gacttggacg atgcagtgca tatcaaggct ctgaaaaatg
    20401 gcaatctgga gcttggggtt cacatcgcag atgtttctta ttatgtgacc gaggggtctg
    20461 cccttgacaa ggaagccctt aaccgtgcga cttctgttta cgtgacagac cgagtggtgc
    20521 caatgcttcc agaacgacta tcaaatggca tctgctctct caatccccaa gttgaccgcc
    20581 tgacccagtc tgctattatg gagattgata aacatggtcg tgtggtcaac tataccatta
    20641 cacaaacagt tatcaagacc agttttcgta tgacctatag cgatgtcaat gatatcctag
    20701 ctggcgatga agaaaagaga aaaaaatatc ataaaattgt accaagtatc gaactcatgg
    20761 ccaagcttca tgaaacttta gaaaacatgc gtgtgaaacg tggagctctc aattttgata
    20821 ccaatgaagc gaagatttta gtggataaac aaggtaagcc tgttgatatc gttcttcggc
    20881 agcgtggtat tgccgagcgg attattgagt cttttatgtt gatggctaat gaaacagttg
    20941 ccgaacattt cagcaagttg gatttgcctt ttatctatcg aattcacgag gagcctaagg
    21001 ctgaaaaggt tcagaagttt attgattatg cttcgagttt tggcttgcgc atttatggga
    21061 ctgccagtga gattagtcag gaggcacttc aagacatcat gcgtgctgtt gagggagaac
    21121 cttatgcaga tgtattgtcc atgatgcttc ttcgctctat gcagcaggct cgttattcgg
    21181 agcacaatca cggccactat ggactagctg ctgactatta tactcacttt accagtccaa
    21241 ttcgtcgtta tccagacctt cttgttcacc gtatgattcg agattacggc tgttctaagg
    21301 aaatagcaga gcattttgaa caagtgattc cagagattgc gacccagtct tccaaccgtg
    21361 aacgtcgtgc catagaagct gagcgtgaag tcgaagccat gaaaaaggct gagtatatgg
    21421 aagaatacgt gggtgaagag tatgatgcag ttgtatcaag tattgtcaaa ttcggtctct
    21481 ttgtcgaatt gccaaacaca gttgaaggct tgattcacat cactaatcta cctgaatttt
    21541 atcatttcaa tgagcgtgat ttgactcttc gtggagaaaa atcaggtatc actttccgag
    21601 tgggtcagca gatccgtatc cgtgttgaaa gagcggataa aatgactgga gagattgatt
    21661 tttcattcgt acctagtgag tttgatgtga ttgaaaaagg cttgaaacag tctagtcgta
    21721 gtggcagagg gcgtggttca aatcgtcgtt cggataagaa ggaagacaag agaaaattag
    21781 gacgctcaaa tgataagcgt aagcattcac aaaaagacaa gaagaaaaaa ggaaagaaac
    21841 ctttttacaa ggaagtagct aagaaaggag ccaagcatgg caaagggcga gggaaaggtc
    21901 gtcgcacaaa ataaaaaggc acgccacgac tatacaatcg tagatacgct agaggcaggg
    21961 atggtcctga ctggaactga aatcaagagt gtacgagctg ctcgaattaa tctcaaggat
    22021 ggctttgctc aagtgaaaaa tggagaagtt tggctgagca atgttcatat cgcgccttac
    22081 gaagagggca atatctggaa ccaggaacca gaacgtcgtc gtaaactcct gctccataaa
    22141 aagcaaattc aaaaattgga acaagagacc aaagggacag gaatgacctt agttcccctt
    22201 aaggtctata taaaagatgg ctacgctaag cttcttttag gacttgccaa agggaagcat
    22261 gactatgaca agcgggagtc tatcaaacgt cgtgagcaaa atcgagatat cgcgcgtgtg
    22321 atgaaagctg ttaatcagcg ataaaaagag gaattgaaaa tggaaaaatt agttgcctat
    22381 aaacgcatgc ctttgtggaa taaacaaaca atgcctgaag ctgttcagca aaagcacaat
    22441 acaaaagttg ggacttgggg gaaaattact gtcttgaagg gagctctcaa gtttattgaa
    22501 ttgacagaag aaggggaagt tctagctgaa cacctctttg aagcaggggc agacaatcca
    22561 atggcccaac ctcaagcctg gcaccgagtg gaagctgcca cagatgatgt ggaatggtac
    22621 ttggaatttt attgtaaacc tgaggattat tttgctaaaa aatacaatac caatcctgtt
    22681 cattcagagg tcctagaggc catgcagaca gtgaaacaag ggaaagcttt ggatttgggt
    22741 tgtggtcagg ggcgtaattc tctttttcta gcccagcaag attttgatgt gacggctgta
    22801 gatcaaaatg gactggctct tgaaatcttg caaagcattg tggagcagga agatttggac
    22861 atgcctgttg gcctttacga tatcaattca gctagcattg gacaagaata tgattttatc
    22921 gtttcaacag ttgttctcat gtttctacaa gcggaccgca ttccagctat tattcaaaat
    22981 atgcaggaga aaaccagtgt tggtggttac aaccttatcg tttgtgccat ggacacggag
    23041 gattatcctt gctcggttaa tttcccattc acctttaaag aaggagaact ggcagactat
    23101 tacaaggatt gggaattggt taagtacaat gaaaatccag gccatttgca ccgtcgcgat
    23161 gagaatggca atcgtattca actacgcttt gcgaccttac tagctaagaa aatcaagtaa
    23221 acacacatga agattaggaa ttttcctgat cttttttctt ttttacgaat gatatagaaa
    23281 aggagggaat tcatgtttgt tgcgagagat gctaggggag aattggtaaa tgtgttagag
    23341 gataaacttg agaagcaagc atacacctgc ccagcttgtg gaggccagct ccatttgcgt
    23401 caaggaccaa gtgtacggac gcattttgcc cataaatcct taaaagactg tgattttttc
    23461 tttgaaaatg aaagtccaga acacctggtc aataaggaat ccctctatca ctggttgaaa
    23521 aaagagacaa aggttcaatt agagtacccg ctttcagaac ttaaacagat tgcggatgta
    23581 tttgtaaatg gcaatctagc tctagaagtt cagtgtagtc ccttgcctca gaaagtcctt
    23641 aaagagcgaa gtgagggcta tcgtagtcag ggttacaaag tactgtggtt gctgggtcaa
    23701 aaactgtggc tcaaggagcg tttgactcgt ctacagcaag gttttctgta tttcagtcaa
    23761 aacatgggct tttatgtttg ggaattagac aaggaaaaac aagttttaag actcaaatac
    23821 ctgatttacc aggatctccg cggtaaactc cattatcaaa tcaaggaatt ttcctatggt
    23881 caaggtagtt tattggaaat attgcgtctt ccctataaga gacaaaaaat atctcatttt
    23941 acagtttctg aggacaagga catctgtcgc tatatccggc aacaacttta ttatcaaaat
    24001 ctcttttgga tgaaagaaca agcagaagcc tatcaaaagg gagaaaatat cctgacttat
    24061 gggctgaaag aatggtatcc acaaattcga ccaatagtgg gcaaattttt ccagattgaa
    24121 caagacttga ctagctatta tcagcatttt tatacctatt accaaaaaaa tcctcaaaat
    24181 gattggcaaa agctttatcc accagccttt tatcagcaat atttcttgaa aaatatggta
    24241 gaatagaaag gatggaggaa tctaatggta ttacaaagaa atgaaataaa tgaaaaagat
    24301 acatgggatc tatcaacgat ctacccaact gaccaggctt gggaagaagc cttaaaagat
    24361 ttaacagaac aattggagac agtagcccag tatgaaggcc atctcttgga tagtgcggat
    24421 aacctactag aaatcactga attttctctt gaaatggaac gccagataga gaagctttac
    24481 gtttatgctc atatgaagaa tgaccaggat acacgtgaag ctaagtatca agagtactat
    24541 gccaaggcca tgacattcta cagtcagtta gaccaagcct tttcattcta tgagcctgaa
    24601 tttatggaga ttagcgaaaa gcagtatgct gactttttag aagctcaacc aaagctgcag
    24661 gtttatcaac actattttga caagctcttg caaggcaagg atcacgttct ttcacaacgt
    24721 gaagaagaat tattggctgg agctggagaa atctttggtt cagcaagtga aacctttgct
    24781 atcttggaca atgcggatat tgtgttccct tatgtcctag acgatgatgg taaagaagtt
    24841 cagctatctc atgggactta cacacgtttg atggagtcta aaaaacgtga ggttcgccgt
    24901 ggtgcctatc aagctcttta tgcgacttac gaacaattcc aacacaccta tgccaaaacc
    24961 ttgcaaacca atgttaaggt gcaaaattac cgtgctaaag ttcgtaacta caagagtgct
    25021 cgtcatgcag tcctcgcagc gaattttgtt ccagaaagtg tttatgacaa tttggtagca
    25081 gcagttcgca agcatttgcc actcttacat cgctatcttg agcttcgttc aaaaatcttg
    25141 gggatttcag atctcaagat gtacgatgtc tacacaccgc tttcatctgt tgaatacagt
    25201 tttacctacc aagaagcctt gaaaaaagca gaagatgctt tggcagtctt gggtgaggat
    25261 tacttgagcc gtgttaaacg tgccttcagc gagcgttgga ttgatgttta cgaaaatcaa
    25321 ggcaagcgtt caggtgccta ctctggtggt tcttacgata ccaatgcctt tatgcttctc
    25381 aactggcagg acaatctgga caatctcttt actcttgttc atgaaacagg tcacagtatg
    25441 cattcaagct atactcgtga aactcagcct tatgtttacg gagattactc tatctttttg
    25501 gctgagattg cctcaactac caatgaaaat atcttgacgg agaaattatt ggaagaagtg
    25561 gaagacgacg caacacgctt tgctattctc aataacttcc tagatggttt ccgtggaaca
    25621 gttttccgcc aaactcaatt tgctgagttt gaacacgcca ttcaccaagc agatcaaaat
    25681 ggggaggtct tgacaagcga tttcctaaat aaactctacg cagacttgaa ccaagagtat
    25741 tatggtttga gtaaggaaga caatcctgaa atccaatacg agtgggctcg cattccacac
    25801 ttctactata actactatgt atatcaatat tcaactggct ttgcggccgc ctcagccttg
    25861 gctgaaaaaa ttgtccatgg tagtcaagaa gaccgtgacc gctatatcga ctacctcaag
    25921 gcaggtaagt cggactatcc acttaatgtc atgagaaaag ctggtgttga tatggagaag
    25981 gaagactacc tcaacgatgc ctttgcagtc tttgaacgcc gtttaaatga gtttgaagcc
    26041 cttgttgaaa aattaggatt ggcataaaat ggttgaatcg tatagtaaga atgctaacca
    26101 taacatgcgt cgtcctgtcg tcaaagaaga aattgtagac ttgatgcgtc agcgtcaaaa
    26161 gcaagtcaca ggttccttga aagaattgga agactttgcc cgcaaggaaa atattcctat
    26221 tattccccat gaaacggttg cttatttccg ttttcttatg gaaaccatgc agcctaaaaa
    26281 tattctggaa attgggacgg ctatcggttt ttcagctctc ttgatggctg aacatgcgcc
    26341 aaatgctaag attacaacta ttgatcgtaa tccagaaatg attggttttg ccaaggaaaa
    26401 ttttgcccag tttgacagtc gcaagcaaat cactctccta gagggagatg cggtggatgt
    26461 cttatctaca ctgacagagt cttatgattt cgtctttatg gattctgcca agtctaaata
    26521 catcgtcttt ctgccagaaa tcctcaaaca tttggaagtt ggtggtgtgg ttgtcttgga
    26581 tgatattttt caaggtggtg atgttgccaa ggatattatg gaagtccgtc gtggtcagcg
    26641 aaccatttat cgaggccttc aaaaattatt tgatgcaacc ttagacaatc cagaactcac
    26701 cgcaacatta gtgcctttag gagatggtat tctcatgctt cgtaaaaatg tagcagatgt
    26761 tcaactgtct gaaagcgaat gattttcaga aaaatttaag aaaaaatagt aaaatagata
    26821 gagtaacact tatctcaaag gagtagacat gaagaaaaaa ttattggcag gtgccatcac
    26881 actattatca gtagcaactt tagcagcttg ttcgaaaggg tcagaaggag cagaccttat
    26941 cagcatgaaa ggggatgtca tcacagaaca tcaattttat gagcaagtga aaaacaaccc
    27001 ttcagcccaa caagtcttgt taaatatgac catccaaaaa gtttttgaaa aacaatatgg
    27061 ctcagagctt gatgataaag aggttgatga tactattgcc gaagaaaaaa aacaatatgg
    27121 cgaaaactac caacgtgtct tgtcacaagc aggtatgact cttgaaacac gtaaagctca
    27181 aattcgtaca agtaaattag ttgagttggc agttaagaag gtagcagaag ctgaattgac
    27241 agatgaagcc tataagaaag cctttgatga gtacactcca gatgtaacgg ctcaaatcat
    27301 ccgtcttaat aatgaagata aggccaaaga agttctcgaa aaagccaagg cagaaggtgc
    27361 tgattttgct caattagcca aagataattc aactgatgaa aaaacaaaag aaaatggtgg
    27421 agaaattacc tttgattctg cttcaacaga agtacctgag caagtcaaaa aagccgcttt
    27481 cgctttagat gtggatggtg tttctgatgt gattacagca actggcacac aagcctacag
    27541 tagccaatat tacattgtaa aactcactaa gaaaacagaa aaatcatcta atattgatga
    27601 ctacaaagaa aaattaaaaa ctgttatctt gactcaaaaa caaaatgatt caacatttgt
    27661 tcaaagcatt atcggaaaag aattgcaagc agccaatatc aaggttaagg accaagcctt
    27721 ccaaaatatc tttacccaat atatcggtgg tggagattca agctcaagca gtagtacatc
    27781 aaacgaatag tccaaatcaa tgagtcaggg aaaaaactcg acttcaggaa aaaatgaagc
    27841 aaacattccc acaataaaac gcatagtaca aggtttgtac tgccccccaa aaaagttaga
    27901 caattaattt atccgaagga tttagttctg tattgcacag agctaagtcc ttttagtttt
    27961 atcttaattc tcttattgtt gtaataatca atatagtcta taatggcttg ttccaattga
    28021 ttaagtgatt taaatgtttg ctcatagcca taaaacattt cggattttaa aatgccaaag
    28081 aaagattcca tcctaccgtt gtcttggctg tttcctttgc gtgacataga tgcttgaatt
    28141 cccttactct ctaggaagcg atgataagaa tcgtgttggt attgccagcc ttggtcacta
    28201 tggagaatcg tattctcgta gtgcttctct ttgaatgcct gttccaacat taacgatcaa
    28261 tcaatttaat catgtaccta agattagaat tgtttatccc aaatttattt gaaagcttct
    28321 ctaagctata tccttgtttt ctaagttcat agatctgaac tttatcatca taagttaatt
    28381 tcataataaa aacaccccaa aagttagatt ttttctgtct aacttttggg gtgtagttca
    28441 tgtacacctg atatgatgcg ttttataatt ttaaagactt tttgaccagc ctcatttttt
    28501 taacttgata ctcagtgaaa agcaaagatt aaactaggaa gctagctgta ggctgctcaa
    28561 agaacagctt tgaggttgca gataaaactt gtgaggtaac caacatatat aatgtgaagc
    28621 tgacgtggtt tgaatagatt ttagaagggt atgagtctgg aagttttaat ggataatgca
    28681 agattccata gaatgggtaa gctagagttc ttatgtgaag agtttgggca taaactttta
    28741 ccttttcctc cctactcatc ttagtataga aaagtgaatc taaaatagta cataactgct
    28801 tctaaaacat tcttataaat tgatttaaat tctcaaatca tattattcag ttcttatttc
    28861 attttgctct acaatcctgt tgagaagaca cgtgttcata tcaaaaaggt attggcaagt
    28921 tgcaatacct ttttacaagg ttcttttgtc ttatttttgt ttcaactgac tatatctcct
    28981 atggttctag ttcagaaggc taggctataa ttatgattga taagaagtat cattccaagt
    29041 attgagagtg aatgtttcaa aatcatgggt ttctataatg gtcaggctgg catttgctag
    29101 accgccatct ttacgaagaa gtggttcttt atagcctagg agagtacgaa gactggcagt
    29161 aagattggcg ccgtgtccga caattagaat acgctcagct ggactatctt ttaatgattt
    29221 gataaattgg atggtccgct gagttgtact atagagggat tcggctccga acattcgagt
    29281 gtcaaattga gcaagatttg aacgaaaagc ctggatttgt tgcgggtaaa tagcttccag
    29341 ggttgcaatt ttcaaacctt ctaacttccc aagttgccat tcacggagat taggaacgat
    29401 ttctaaagaa cagggggtat ggagttgact ttggataatc tcagcagatt tgaccgctcg
    29461 aggtaaatca cttgaataaa tctgatcaaa aggaatttcc ttgagatact ggccaagtcg
    29521 ttttagggtt tcaatggatt caggaagaag aggagaatca ccgctagcac cttgaaaacg
    29581 accttcttgg ttccagaggg tacgaccgtg gcggacaaag tagagtttca ttacttgatg
    29641 tcctccaaaa tatctacaaa gtctgccttt acaaagctag ccaagtcttg tggcgcgacg
    29701 ataatgctgt gtccgacttc gcctgcagag acaatcattc gatccaaatc tagagcaatt
    29761 ttatcgataa aaatgggata attgtgtttc tgacgaattc cgacaggatt attggctcca
    29821 tgaatgtaac cagttgtttt ttctaagtcc ttttgtggaa tcatgctcac ttttttattg
    29881 ccagaaattt tagctagttt cttttcagac aagtgctgag tgatagggac aattccgata
    29941 atcggtccgg tcttgtctcc caaaagcgcc aaggttttga aaatctgatc tcgttcataa
    30001 ccttgaggaa gctctccttc tagggcattg atttgaatcc cctgatgagg gatagctgct
    30061 ttagatagga tttgttccac caatgttttt ttgattttaa ctttttttgc cattatttat
    30121 atttatcctc caattgactc atccaaatac caagccagat tcccagcgca aagaagaagg
    30181 cgatgatgac ataaccgaca agtgaaagtc ctgtgtattg gatactttca gcgtttcctg
    30241 catttggaat taagatcaaa agggtacttg ataggacgat accgatgatg aaatgataga
    30301 cgcgtgagtg gtagttgttt aaggcataat ccatcaattt tgaaaaaacg atgagagttg
    30361 cacctgcacc aattccaatc ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag
    30421 tcaacatagg agcatagagt cccaaaatca aaagtaaatt tgatgggctg aggccaggaa
    30481 ccaagacgcc aagggccaat agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta
    30541 aggttccaac gacaaaattt aaggcataga gtcctaatcc agaaatgata aaggttgtcc
    30601 ataaccaagc taaatcaatc ttgtctcggt cagattctcg agttgattct ttgaggatgc
    30661 taggaactgt accgataata gctcccgcaa agctccataa tacaaagacc tgataatttt
    30721 caagcaggta ttcaatcggg taggaaaata agccgattcc cagaagcata ccgatggcaa
    30781 ctggaataaa gtacaaaaca ttttctttaa ggtctttaaa gggatgggcc agaaagccaa
    30841 tcattcgttc atagattcct aagattgctg ctagaacccc tccggaaatt cccggtagga
    30901 taaatccaag agcaattaca atccctttaa taacgcgtgc taaccatgag agcatatatt
    30961 tcctccaact atttctattt caaaaaatcc ttactatatt gtatcacaat cagacacaaa
    31021 aagaaaaagc aaatgataaa caaatgcttt taaggtttta aaaaaagttt tcgaaaggtt
    31081 tcttctttat tttttaaggg agagataacg ttgatatcta aatcgtggtc aaagccggca
    31141 atttttcctt tagatgtgta ttggtgaata tcatagtcta aatcagtttt aggactgctc
    31201 tccaaaaatc ctgagtctga gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta
    31261 tcaatactgt gttcttccat gaagtagaca ccaacgtaga tgccgatgtt tttagcacct
    31321 agtgatgcta gttttgctcg aaagttttcg acaccttcgt tcatattaga catggttttg
    31381 tcttccacgt caagccaata gtaactaggg ctgtaaggag aggcagcatt gtagaaaact
    31441 tcggcagcat tttccatttc ttggacactt tttccagcta cataagcgta gacagcaact
    31501 gggacattcc gcttttgaag ttcagtgata tgactcttat aggccttgtc tattccattg
    31561 ataaatgaag catcattttc ttttgtcgtt tgagcaccac tgtgaacacg aacaatagca
    31621 cctgaaatat tttgtgagag ggcatcgtag ttgatttcct caggacgctg ccagccagag
    31681 aggtcaataa tcggtttgtc taagtgtttc aaagcctgtg cttcaatctg tgctatattg
    31741 gattttgttt taaacgattg gttgtcatta agtgggcgat tgatgattaa aatgaacatc
    31801 ataatcccaa aaaaactaaa taaaataagt ggatgaattt gttttctcat atcttataat
    31861 tctaccctaa aaatcaaaaa aaatcaaaaa aatgggttaa ggaagagact ttagagcatt
    31921 ttttcattca agagtgcgga atgatttgaa atatggtata ataaaaggga atttctacag
    31981 aaaagagaag attatgtcaa attttgccat tattttagca gcgggtaaag ggactcgcat
    32041 gaaatctgat ttgccaaaag ttttgcacaa ggttgcgggt atttctatgt tggaacatgt
    32101 tttccgtagt gtgggagcta tccaacctga aaagacagta acagttgtag gacacaaggc
    32161 agaattggtt gaggaggtct tggctggaca gacagaattt gtgactcaat ctgaacagtt
    32221 gggaactggt catgcagtta tgatgacaga acctatctta gaaggtttgt caggacacac
    32281 cttggtcatt gcaggagata ctcctttaat cactggtgaa agcttgaaaa acttgattga
    32341 tttccatatc aatcataaaa atgtggccac tatcttgact gctgaaacgg ataatccttt
    32401 tggctatgga cgaattgttc gtaatgacaa tgctgaggtt cttcgtattg ttgagcagaa
    32461 ggatgctaca gattttgaaa agcaaatcaa ggaaatcaac actggaacat acgtctttga
    32521 caacgagcgt ttgtttgagg ctttgaaaaa tatcaatacc aataacgctc aaggcgaata
    32581 ctatattaca gacgtcattg gtattttccg tgaaactggt gaaaaagttg gcgcttatac
    32641 tttgaaagat tttgatgaaa gtcttggggt aaatgaccgt gtggcgcttg cgacagctga
    32701 gtcagttatg cgtcgtcgca tcaatcataa acacatggtc aacggtgtta gctttgtcaa
    32761 tccagaagca acttatatcg atattgatgt tgagattgct ccggaagttc aaatcgaagc
    32821 caatgttacc ttgaaagggc aaacgaaaat tggtgctgag actgttttga caaacggtac
    32881 ttatgtagtg gacagcacta tcggagcagg agcggtcatt accaattcta tgattgagga
    32941 aagtagtgtt gcagacggtg tgacagtcgg tccttatgct cacattcgtc caaattcaag
    33001 tctgggtgcc caagttcata ttggtaactt tgttgaggtg aaaggatctt caatcggtga
    33061 gaataccaag gctggtcatt tgacttatat cggaaactgt gaagtgggaa gcaacgttaa
    33121 tttcggtgct ggaactatta cagtcaacta tgacggcaaa aacaaataca agacagtcat
    33181 tggagacaat gtctttgttg gttcaaattc aaccattatt gcaccagtag aacttggtga
    33241 caattccctc gttggtgctg gttcaactat tactaaagac gtgccagcag atgctattgc
    33301 tattggtcgc ggtcgtcaga tcaataaaga cgaatatgca acacgtcttc ctcatcatcc
    33361 taagaaccag taggagccta tcatggagtt tgaagaaaaa acgcttagcc gaaaagaaat
    33421 ctatcaagga ccaatattta aactggtcca agatcaggtt gaattaccag aaggcaaggg
    33481 aactgcccaa cgggatttga ttttccacaa tggggctgtc tgtgttttag cagtaacgga
    33541 tgaacaaaaa cttatcttgg tcaagcagta ccgcaaagct atcgaggctg tctcttacga
    33601 aattccagcc ggaaaattgg aagtaggaga aaacacagcc cctgtggcag ctgcccttcg
    33661 tgaattagag gaagaaacag cctatacagg gaaattagaa ctcttgtacg atttttattc
    33721 agctattggc ttttgtaatg agaagttaaa actatattta gcaagcgatt tgacaaaagt
    33781 ggaaaatccg cgtccgcagg atgaggatga aaccttggaa gtccttgaag tgagcttaga
    33841 agaagcgaaa gaattaatcc aatcaggtca tatttgtgat gccaagacaa ttatggctgt
    33901 tcagtattgg gagttgcaga aaaaatagag gaggtcagta tgggtaaatc tttattaacg
    33961 gatgaaatga ttgaaagagc taatagaggc gaaaaaattt caggtcctcc tttgctagat
    34021 gataatgagg aaactaagat tttaccaacc tcttcttccc gttttggtta tgccaatcct
    34081 aaggatcatg gttttagcca ggaaaccttg aagattcagg tcgaaccatc tattcataaa
    34141 agccgtcgta ttgaaaatac caagagaaat gtcttcaatt ctaagttgaa taaaatctta
    34201 ttcgcggtca tctttctctt gattttgctt gttttagcaa tgaaactttt gtaatagaaa
    34261 aggaattgaa atgaaaatag gaattattgc tgctatgcca gaagaactgg cttatctggt
    34321 ccagcattta gacaatgccc aggagcaagt tgttttgggg aatacctatc atacaggaac
    34381 cattgcttct catgaaatcg ttcttgtaga aagtggaatt ggtaaggtca tgtctgctat
    34441 gagtgtggcg attttggctg atcatttcca ggtggatgcc cttattaata cgggttcagc
    34501 tggggcagta gcagaaggta tcgctgttgg ggatgtcgtg attgctgaca aattagccta
    34561 tcatgacgtg gatgtcacag cttttggcta tgcttatgga caaatggcgc aacaaccgct
    34621 ttatttcgaa tcagacaaaa cctttgttgc tcaaatccaa gagagtttat ctcaattgga
    34681 ccaaaactgg catcttggtt tgattgctac aggagatagt tttgttgcag gaaatgacaa
    34741 gatagaagcg attaagtccc atttcccaga agttttagcc gtggagatgg agggggcagc
    34801 tattgctcaa gcagcgcatg ccctcaatct cccagtctta gtcatcagag ctatgagtga
    34861 caatgccaac catgaagcaa acatcttttt tgatgagttt attatcgaag ctggacgtcg
    34921 ctctgcccaa gtcttgttga cctttttgaa ggctttagat taagcggaaa tttgacagtt
    34981 tttctagctt atgataagat ttaagtaaag aaaagctaga aaacgtttca gaggatatta
    35041 tgagtattga aatgaccgtc agtgagattg cagaggtctt aggattatct cgccaagcaa
    35101 tcaataaccg tgtcaaagaa ttaccagaag aagacacaga taaaaatgac aaaggggtaa
    35161 cagttgttac cagaagtggc ttgattaagc tagaagaaat ctataaaaaa acgatttttg
    35221 aagatgaacc tgtcagtgaa gatgtcaaac aacgtgaact gatggagatt ctagtggatg
    35281 agaagaatgc agaaattctt cgtctttatg aacaattaaa agccaaggat cgtcagttat
    35341 cagaaaaaga cgagcagatg cgtatcaaag accgtcagat tgctgagaaa gacaaacaat
    35401 tagatcagca acaacaattg acccttcaag ccatgaagga tcaagaaaat cttaagctag
    35461 agctggacca agcaaaagaa gaagtccaat ccactaaaaa aggctttttt gctcgtttat
    35521 ttggaggata atcaaggagc tgtttaggtt aaatgctaac ctgatggctt cttttgtttg
    35581 tgaatagtat agttgattag aacagagaca gtagaggaga ggtacagaat ggaacgatta
    35641 gaagattaca ttgcttttga tttagaattt aatcagcacg aaggacaaac acacttgatt
    35701 caagtatcgg cagtgcgttt tagagatggt cgggaaatcg atgcctatga ttcctatgtt
    35761 cataccagcg tctctctaaa aagctttatc aatggtttga ccgggattac agctgagacc
    35821 ttaaaagatg ctcctccagt tgagaaagtc ttagaagaat tccaagagtt tgtgggttct
    35881 ttgctgatga taggctacaa tgctgctaaa agtgatttac ctattttagc agagcatggt
    35941 ttagactata gccaacagta caaggtggat ttgtatgatg aagcttttga acgtcggagt
    36001 tcagatttac atggtattgc caatctcaaa ttgcaaactg ttgcctcatt tcttggattt
    36061 caaggtcagt ctcataatag tttagaggat gctcggatga cggcgcgtgt ttacgaatcc
    36121 ttcttagagt cggatcaagc tagggaattg ttagagacag aaagtagctt atcaaacaat
    36181 ccttttggtg gcttggactt gtctcaatta tttgactagg agtgcctatg aaacctgaaa
    36241 aacctaaaaa attgggtctt aaacagattt acctcaatct tgataaaatc ctctttctat
    36301 ttttcttgat ttttatgata gtggagtatt tgtgggtacc attcaattca tggttggcta
    36361 gcttcttatt agatcagaca ggttatcttt ttatttccta taacaatgtc ttagccatcc
    36421 ttactcattc tccattgatt agtctagctt ttttagcctt gattgtaatt aaccttctgg
    36481 ttgcttattt tcaaatagga ctcctcttta ttggtgctcg tcatctcctc tataatgaaa
    36541 agcgaaggct aattgagtat atccgcaagg ttttccatga aagttttgga tttatgaaaa
    36601 agctaacttg cgctaaagcc ttgtttatct ttttctatat agctatgctt tttcctttta
    36661 tacggaaaat gctgaagatt tattatctta ataaaatcgt cattccagag tttatccaag
    36721 cttatttaga agataaatat tggatgtggt ggctgagcat cctacttcta tctcttatct
    36781 ttctctatgt ctctgtcaga ttgatgtttg cccttccgaa gattgtatat gatcagctga
    36841 ctgttcgaga agcagtgatg tttagcttgg agaaaaccaa gaagagagtt actttttatg
    36901 cttggaattt attttacatc ttgctcaaag cacatttatt attttatctt cctttgattc
    36961 ctttattatt ggctcaaact ttggtagatg atatcactca gagagagtct ctgattcttg
    37021 gtattttgaa ttttgtcgtg attaaaaatc tctattatat ggctctgact tattttttgg
    37081 ttaaatttgt ttcatttttg acaggaaagg agctggatat gcttcctagg agagaaaaag
    37141 atcacatcgt gcgatggggt gtcatgactt gtgccagtct tttctttgcc ttagaaggtt
    37201 atatttatct ggaggctccc atggttcatc tacctcaact tatttctcac cgaggggttt
    37261 ccaatgcaaa tgggattcaa aatacagtag agtccttgga aactacagca caactcaaac
    37321 cagacttggt ggagacggac gtgcaggaaa caaaagatgg gcagtttgtc atgatgcatg
    37381 atgctaactt gaaaaatcta gcaggtatca ataaaagtcc tcaagactta aacttggagg
    37441 agcttaaagg gattgatatt tttgaaaatg gctaccagac taaaatttca agctttgaag
    37501 attatctcag tcgagccaac gaacttggtc aaaaattact aattgaaatt aaaaccagta
    37561 aaaaagatag tccagacatg atgaaccgct ttttagcccg ttatgctgca aagctcaaga
    37621 tttatggaca tcaaatccag tctttagact accatgttgt cgaaaaagta agacagtatg
    37681 atgccgaact gccagtttat ttcatcatgc cctacaattc tgtctttcct aaaacaagag
    37741 cgacaggata tactatggag tactcaacct tggatgaata ttttgtaagc aaactatgga
    37801 caacggatca gaaactttat gtctggactg tcaatgattc agaagctatc agcaaatctc
    37861 ttcacttagg agtagatgga gtgattacag atgatttgga aaaagttcag cgggaaatag
    37921 aagtagccca agaagatcca gaatatacgg atttgctctt gaaaaaagca ttggaattct
    37981 ttgaatttta gtaataaaaa agaggaactg ttgttcctcc catgataggt aagtattctt
    38041 gtgaatgctt gcttttttgt ggttgcaatc cgtttacgag aattgtttgt attgttcttg
    38101 tttcaattta ctttatagtg ctttgaagtt ggaatactac actataactt ct
//
LOCUS       DAVDFK010000018        36580 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.18, whole genome shotgun sequence.
ACCESSION   DAVDFK010000018 DAVDFK010000000
VERSION     DAVDFK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36580
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.18"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..423)
                     /locus_tag="VUR04_001133"
     CDS             complement(<1..423)
                     /locus_tag="VUR04_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5341035.1"
                     /translation="MPKKYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(811..1605)
                     /locus_tag="VUR04_001134"
     CDS             complement(811..1605)
                     /locus_tag="VUR04_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341036.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVMANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(1605..2612)
                     /locus_tag="VUR04_001135"
     CDS             complement(1605..2612)
                     /locus_tag="VUR04_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5341037.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANLELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(2612..3619)
                     /locus_tag="VUR04_001136"
     CDS             complement(2612..3619)
                     /locus_tag="VUR04_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5341038.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(3609..4634)
                     /locus_tag="VUR04_001137"
     CDS             complement(3609..4634)
                     /locus_tag="VUR04_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET5341039.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(4755..5024)
                     /locus_tag="VUR04_001138"
     CDS             complement(4755..5024)
                     /locus_tag="VUR04_001138"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341040.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFIDELMKNIDII"
     gene            complement(5028..5246)
                     /locus_tag="VUR04_001139"
     CDS             complement(5028..5246)
                     /locus_tag="VUR04_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341041.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(5537..5770)
                     /locus_tag="VUR04_001140"
     CDS             complement(5537..5770)
                     /locus_tag="VUR04_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HET5341042.1"
                     /translation="MKKDKEVYDNVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(5984..7615)
                     /gene="rlmD"
                     /locus_tag="VUR04_001141"
     CDS             complement(5984..7615)
                     /gene="rlmD"
                     /locus_tag="VUR04_001141"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET5341043.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     RKHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(7689..8663)
                     /locus_tag="VUR04_001142"
     CDS             complement(7689..8663)
                     /locus_tag="VUR04_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET5341044.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGDQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(8737..9351)
                     /gene="pmp23"
                     /locus_tag="VUR04_001143"
     CDS             complement(8737..9351)
                     /gene="pmp23"
                     /locus_tag="VUR04_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET5341045.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(9351..10325)
                     /locus_tag="VUR04_001144"
     CDS             complement(9351..10325)
                     /locus_tag="VUR04_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET5341046.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(10333..11589)
                     /locus_tag="VUR04_001145"
     CDS             complement(10333..11589)
                     /locus_tag="VUR04_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET5341047.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMALIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(11651..12082)
                     /locus_tag="VUR04_001146"
     CDS             complement(11651..12082)
                     /locus_tag="VUR04_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341048.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     RRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(12084..12686)
                     /locus_tag="VUR04_001147"
     CDS             complement(12084..12686)
                     /locus_tag="VUR04_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET5341049.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGSLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(12670..13509)
                     /gene="prmC"
                     /locus_tag="VUR04_001148"
     CDS             complement(12670..13509)
                     /gene="prmC"
                     /locus_tag="VUR04_001148"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET5341050.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFIEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(13509..14588)
                     /gene="prfA"
                     /locus_tag="VUR04_001149"
     CDS             complement(13509..14588)
                     /gene="prfA"
                     /locus_tag="VUR04_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET5341051.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVIPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(14585..15175)
                     /locus_tag="VUR04_001150"
     CDS             complement(14585..15175)
                     /locus_tag="VUR04_001150"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET5341052.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPEINKENEEK"
     gene            15298..15480
                     /locus_tag="VUR04_001151"
     CDS             15298..15480
                     /locus_tag="VUR04_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET5341053.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            15616..16989
                     /gene="mnmE"
                     /locus_tag="VUR04_001152"
     CDS             15616..16989
                     /gene="mnmE"
                     /locus_tag="VUR04_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET5341054.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(17036..17971)
                     /gene="dapA"
                     /locus_tag="VUR04_001153"
     CDS             complement(17036..17971)
                     /gene="dapA"
                     /locus_tag="VUR04_001153"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET5341055.1"
                     /translation="MSYQDLKECKIITAFITPFHEGGSINFDAIPALIEHLLDHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKIVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(18027..19103)
                     /locus_tag="VUR04_001154"
     CDS             complement(18027..19103)
                     /locus_tag="VUR04_001154"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET5341056.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(19689..19761)
                     /locus_tag="VUR04_001155"
     tRNA            complement(19689..19761)
                     /locus_tag="VUR04_001155"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19726..19728),aa:Thr,seq:ggt)
     gene            complement(19861..20370)
                     /locus_tag="VUR04_001156"
     CDS             complement(19861..20370)
                     /locus_tag="VUR04_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET5341057.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(20368..20464)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            20493..20924
                     /locus_tag="VUR04_001157"
     CDS             20493..20924
                     /locus_tag="VUR04_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET5341058.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            21006..21383
                     /gene="mscL"
                     /locus_tag="VUR04_001158"
     CDS             21006..21383
                     /gene="mscL"
                     /locus_tag="VUR04_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET5341059.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(21425..22519)
                     /gene="hemH"
                     /locus_tag="VUR04_001159"
     CDS             complement(21425..22519)
                     /gene="hemH"
                     /locus_tag="VUR04_001159"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET5341060.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(22597..23433)
                     /gene="srtG2"
                     /locus_tag="VUR04_001160"
     CDS             complement(22597..23433)
                     /gene="srtG2"
                     /locus_tag="VUR04_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HET5341061.1"
                     /translation="MVFFCVFVALFSWQRVVEASDYDHYNPIEKDASSTGFETLQHLN
                     KDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTITGSIFLDYRFNPNFTDFNTI
                     IYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFGILEVDAYDTEIYR
                     TLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNITNGRHILLAKITDA
                     PVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLIILIIRRDKKTKEQ
                     KK"
     gene            complement(23548..24546)
                     /gene="srtG1"
                     /locus_tag="VUR04_001161"
     CDS             complement(23548..24546)
                     /gene="srtG1"
                     /locus_tag="VUR04_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET5341062.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(24564..25760)
                     /gene="pitB"
                     /locus_tag="VUR04_001162"
     CDS             complement(24564..25760)
                     /gene="pitB"
                     /locus_tag="VUR04_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET5341063.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVESSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(25805..26356)
                     /gene="sipA"
                     /locus_tag="VUR04_001163"
     CDS             complement(25805..26356)
                     /gene="sipA"
                     /locus_tag="VUR04_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET5341064.1"
                     /translation="MLLKKKHKKPVTQVNRYKSPPSVWGDILYLVSKLLMVGFVLATL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(26356..28116)
                     /locus_tag="VUR04_001164"
     CDS             complement(26356..28116)
                     /locus_tag="VUR04_001164"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341065.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYIGSNDSI
                     TSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQL
                     LPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYVL
                     KFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDYS
                     EKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTSP
                     VQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLTV
                     KKILEGEQSPNKSFTINVTLSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYLP
                     RDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANLL
                     QSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLNA
                     RYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVVL
                     PLGGIFFIILLGHLVVNRRK"
     gene            complement(28438..28953)
                     /locus_tag="VUR04_001165"
     CDS             complement(28438..28953)
                     /locus_tag="VUR04_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET5341066.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSTTEPQTT
                     LHKTITPISGQEDQYELSLDITSKLGTETQTETQSEPLDVVLVADFSGSMEERDVWSY
                     SSRRYISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNGRYYNEY
                     YLSYQYGTWPN"
     gene            29312..30535
                     /gene="pepT"
                     /locus_tag="VUR04_001166"
     CDS             29312..30535
                     /gene="pepT"
                     /locus_tag="VUR04_001166"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET5341067.1"
                     /translation="MTYPNLLDHFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEET
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(30571..31200)
                     /locus_tag="VUR04_001167"
     CDS             complement(30571..31200)
                     /locus_tag="VUR04_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341068.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKPYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSPAKNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            31183..31386
                     /locus_tag="VUR04_001168"
     CDS             31183..31386
                     /locus_tag="VUR04_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341069.1"
                     /translation="MICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQGLTEIR
                     NPDKTMFVQDAIRFAQQHGFNMF"
     gene            complement(31657..32668)
                     /locus_tag="VUR04_001169"
                     /pseudo
     CDS             complement(31657..32668)
                     /locus_tag="VUR04_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(32894..35953)
                     /gene="phtE"
                     /locus_tag="VUR04_001170"
     CDS             complement(32894..35953)
                     /gene="phtE"
                     /locus_tag="VUR04_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET5341070.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIGDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNIQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPADSLPEAPNEKPVKPENSTDNGMLNPEGNVGSDPMLDPALEEAPAVD
                     PVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKNLSDLIA"
     gene            complement(36163..>36580)
                     /locus_tag="VUR04_001171"
     CDS             complement(36163..>36580)
                     /locus_tag="VUR04_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET5341071.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPVPIQ"
BASE COUNT        10598 a         7315 c         6497 g        12170 t
ORIGIN      
        1 aatattataa tttgctatat tgcattttaa ttttaagtct tctatatatc tttccatgta
       61 attccaatct ggagtacctc tactgtctat cggtaattta attttgatat ctggcaatac
      121 tgtgctagat atttgatctt tatattcagt attttttaaa gcttgcctaa taattgaagt
      181 taaatagaat gctacttctt tattcaattc tttatttttt aattttaaac aatgaatttt
      241 catatctagg cttgctttat atttatgata aaagactgct cctaaaaatg aaacagatat
      301 aaaattttca aaaactctat aatttttatc atctatatct tcgtagtaac ctaagatacc
      361 attgtcaata tttgtagcac taattctagg agtttttcca tcgagtaaat atttttttgg
      421 aatagatgag cctgttggta cttgactcga tttccccttt ttttcggtaa taaatatttc
      481 tttttatttt gttgtctgat atttttccta cctgtccttt gtaggatgag tattttctag
      541 attttcttga ataacttttt acttgaagtt ttagcttttg aactagtcgt tgtactttct
      601 ttttgtttat tatcagtcct gatcttttta atattgctgt tattctctat atcctatttt
      661 tcattcatga tattctttta ctaattttat cttaaattct gtgctgtatt tgccattaaa
      721 aaactgacct cctttagtta gttttttggc ctaacttttg agggtcagtt caaaatttgc
      781 gacttttaaa tgaattccaa tattcaatta ttaagagcta acatggtgct tgccaatagg
      841 aatcattaga ggcgaattgg aaatagggtc acgtataatt tttgcttcaa gattaaagat
      901 atctttaact agtttatcat ttagtatatc ttcaggcttt ccctctgcaa caagtttacc
      961 ttctttaatt gcaaataggt aatcagcgta tcttgctgtt agatttatat cgtgcaaaat
     1021 catgcaaatg gttgtcttat atttttggtt tagatcagtc aagaggtcta atagttctat
     1081 ttgatatgag atatccaagt aagtagttgg ctcatctaaa agtaggatac ttgtatcttg
     1141 ggctagggct agagctatcc atactctttg cctttgaccc ccagaaagtt cttcaactag
     1201 gttatttgct agatcttcaa cattggccat aaccattgat ctgtttatta tttcaaggtc
     1261 atcttttcca agactcttaa aaggctttct gtaggggaaa cgaccacggc ttacaagatc
     1321 agctactgtt attgattcag ggattattgg agattgaggt aatatagcta tgtgttttgc
     1381 taaatctttt tctttataag aattaattga tttattatca agcaatactt ctccctctaa
     1441 tggctttata agtcgagaca aggttttaat gagtgttgat ttcccacaac catttgaccc
     1501 aataataact gatatttttt cttcaggtat ttttatattt atattttcca agattatttt
     1561 ttcatcataa ccgcaggtaa gattatttga ccacagacct ttcattatat attcctcctg
     1621 ttcattttta ttagtaagta tattaagtat ggtgaaccta acaagccagt tacaacacct
     1681 actggatatc tagctggtaa aatattttga gagaatatgt ctgataacaa aactagtaaa
     1741 attccaacca atccagctaa tattgggctt cttttcttgc caatatttaa ggctatggga
     1801 ccagctaaaa aagatataca agctattggt cctgtaattg aagtagaaaa agcagttaaa
     1861 gatacagcgc aaaaaattaa aacaagcctt gaaagctcga gatttgctcc aagtccgatt
     1921 gctatttctt caccaagttc aataatttct agtcttttat taaaaaataa aactaatata
     1981 gtagcaataa tacttactat tagaacaaga ggtatgtcat ctaactttgt aaaagataaa
     2041 gagccactga gccatctcat aacttcttgt aattcatatc ttgctacttt caacaataaa
     2101 aatgaggtgc ctgctcttgt gacagcttga aaaccaatac ctaatattat cagtcttgct
     2161 gctgaaaaac catctttttt agctagtaaa aataatatta aagatgatgt tagtccacaa
     2221 gttattgaaa taattccagt agttaaacta tttgttttta ataccaatat gcaaaagacc
     2281 gctgcaatag atgaagaact tgtgacaccg attatatcag gacttgcaag aggatttctt
     2341 aacatagttt gaaagataaa tcctgccaat ccaaaagacc agccagctat aattcctgct
     2401 aataattttg gtaatctaat ttccataatc gaaaaactag ctccaggaac agtttcacta
     2461 tttaagactt taatcaaagt tgaaaaagaa taactttcat ctccgataag taaaatgaaa
     2521 aatgatagac tgattattat taataaaaat agtgaggaaa atagtgttat tctatttttt
     2581 cttttttgaa tacctataat taaattttgc attagttatt aacccctcta tttttcatag
     2641 ttacataaat aagtactgga cccccgatta ttgcagtaat tatccctact tcaatttcac
     2701 ctggtttacc taacatacgg ccgattatat cacatataag caagagctct gcacctataa
     2761 aagatgaaga aatggtcatt gtgcgtatat ctttgcttat aaataagcca caaaagtgag
     2821 gaactataag acctacgaag ccaataggtc caccaattgc agtaatactt gaacataaaa
     2881 gcacacttgc aattattgca agtgatctta tcctattaac attaactcca agaccaacag
     2941 ccatttcatc acccatagct aaagcgttta aatctgatga aataaatata gctatcaagt
     3001 gacctaaaat tataaaaggt agtagtgtag atatagaaga taatgtagct gctccaaggc
     3061 tacctatttg ccaaaatcta aatttgtcta agacgttatt attcggtaaa attaaaaaac
     3121 ttacaaaact gcttaaagcc atactaacac aagttcctga taaggcaagt tttatagggg
     3181 taaggcctgc ttttccgctt acagcaatcg cgtatacaaa aattgcactt actaagccac
     3241 caatgattgc aaaacttata tggcttatgc ttgatgaaat tcctaaaaaa gaaagaccaa
     3301 ttactacact aagacttgct cctgtgttta taccgagtat acctggatca gctattgggt
     3361 ttctagtaac tgattgcatc aatacaccgc ttatggcaag actagaacct gctaaaattg
     3421 caaaaatagt tctaggtatt cttttatata taattgattt aataaaatca tcatttgtat
     3481 tgcccattcc aaaagctgct aaaaaatctc tgatattaat ttcttttgtt ccaagcttta
     3541 atgacaaaaa tattgtaata agaagaccta ggcagattac aaaaattatg cctaggttta
     3601 tttgtttttt atttcgcatt tttgcatgca tttcctaaaa gatttaggta ttcttcaata
     3661 gtatagttta ttgaaagtgg tgttggagtg catgaggctg ctaacggtgt attatctgga
     3721 attacagcaa cggcaccatt tttaattgca tttattttac ctaaaagagg atctttttgt
     3781 aaagcttcaa gagttttatc atcaccataa gttatgatta catcagcatc atttatctta
     3841 tttgcttctt ctgcagaaat ttcctttgca aaactatctt cactctcaaa ttcttttaat
     3901 gattcaggga aaactagacc taaatctgtt aaataatttg ctcttggatc tttgctagta
     3961 taaatccaga attttgatgt atctgcagca ttaatcatag taaataatac tttttttcct
     4021 ttgatttttc ctttgatttc tggatgtttt tctaattctt tggatatacg agcttcagta
     4081 tttttgatta actcatcacc ttctttttcc atacctaagg cttttgaatc aattttaatc
     4141 atatctctcc ataaagtttg ccaaggttta gatttgtatg ctgctacagg agcaattttt
     4201 gatagagtgt cataatcttc tttagttata ccagaataac ctgctaagat aacatctggt
     4261 ttagaatttg atattgcttc aaagttaagt ccatccaaat cgtcaaatag gttagcttta
     4321 ccatttagtt ctttgatttt ttcttctgtc catggtaaaa ctcctttatc agcacttaca
     4381 ccgtaatttg cttttgaaaa tccaacagga actattccta aagctaatgc tacatcatga
     4441 tttccccaag caatagttgc aactctttca ggttttttat ctaatatagt ttgaccgaaa
     4501 gcatgatcta aaactatttt atcaggcgca tgctctttag aagtattttc ttcattttta
     4561 acagaattag aagaacaagc gctaaaaact atacacatag ctaaaatagc tattagaaaa
     4621 aatttgtttt tcataaaaac tccttaaaca tatttcaagt ctattgtatc gataataatt
     4681 atcattgtca atagatgcag ttacaaattt aataatataa ttttttcaaa aaaggatcta
     4741 gtttttattt ttagttaaat tatgtctata tttttcatta actcatcaat aaaaatttgt
     4801 ttgctaatat ctctttcttc tgattttgtt tcaaggatta ttgctacatc attcatattt
     4861 ttaggtaaat accaaccatc tggcttatct gaatatccct tgaagcctaa ttgattaaaa
     4921 gtagttattt gaccagtacc ttgattgatg ttttcttcaa cttcattaaa gcctaatact
     4981 tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta ttcctcgtca
     5041 ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc cttacatatt
     5101 ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat aacatttgtt
     5161 gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc taactgtatc
     5221 cataatggtt tatagttaag tgccataata tccctctttt tttcttcatt agatttattt
     5281 aattatagca taaatattga tttcattcaa tcttacattg atttagtgat ttgttttaga
     5341 gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg ggacctctta
     5401 tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt ttttaatttc
     5461 tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt aaagaatctt
     5521 taaattcatt ggtatgctaa ttacaatatc cattattaaa atggatacta taagcagcac
     5581 accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc cttatattta
     5641 cataactatt tgcctctata actattatga cacgaaacca acaagcaagt tcaagcacct
     5701 ccatatcttt attcaaatga ggactaagat attcacaaac attatcataa acctctttat
     5761 cttttttcat aaaagaggca tacaacttag caaatttatc ctaaaatttt ttgttgcctt
     5821 tatcaatcat ttcaacgctc ctttaaatat aaaaatgatc ctatcaatct ttatattgag
     5881 cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat accaagtagg
     5941 aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc attttgaagt
     6001 gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga ataatttgtt
     6061 tatccttttt agacttgttg taatgttttc gtaattctat tccacatttc ttttttatct
     6121 gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat tctttgattt
     6181 gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc tcaatttcaa
     6241 cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg acgtgatgcg
     6301 tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat tcttggtaga
     6361 gtttgatatc acgcgccatg gttgctacat tgcaggagat ataggcgatg cgatcggctc
     6421 ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga ggatcaacca
     6481 agataacggt tggttgaatc ccatctttaa gccaattctt catagcattt tcagctgtgt
     6541 cacagacata atgggcgttt gaaatattgt tcagctgagc atttttttta ctattctcaa
     6601 ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg actgataaac
     6661 caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt aactctgcaa
     6721 agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg taaaaggctg
     6781 ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct tgaccataaa
     6841 gagtgcgcca ctccttacca aaaatcgcat tggtattctg gtcgttgata ttttgcatga
     6901 cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca acacgaaaaa
     6961 cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga ccacgacgca
     7021 ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt aaatcaaaac
     7081 gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc tggataaaga
     7141 aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt tccaagacac
     7201 cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga tgttccatac
     7261 caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga ctgtccttga
     7321 cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa tccgcgattc
     7381 ctgaacgcag gtaagccaaa tctagatctt gattacggtg tggtgactgg acaaggtatt
     7441 tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg agaatttttt
     7501 cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca actcctgccc
     7561 cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt aacattcttt
     7621 tctctttcta ttggccgaca aaaaagacgg caacgttacg gttaccatcc attataccat
     7681 gaaatttctt aagaaccaaa actcttgaaa aagttgacaa gggcttgcca gagggagctt
     7741 aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt gatattttta
     7801 aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt tttagtgaaa
     7861 tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat gatgatattg
     7921 atctggtctc ctgttatgac ttgatcaagt ttgtaatttt ttaaggtatc ttcaacaatc
     7981 ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc gagtcctgac
     8041 ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt gtccttgttt
     8101 tcagcattga tatctgacaa agccttcaac tcttcttgag ccaaatcttt attagcttgt
     8161 ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc actctcacct
     8221 gtaactggaa tgggtgctgc tacagtgatt ttggcgtgtt ccacacccaa agttacggct
     8281 gcatttcggt acatatcctg agttacctta gtgatgtttt caggtgtttc aatcttgacc
     8341 tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa ctgtaagcta
     8401 gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt cttgagttct
     8461 ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt ttggtcttca
     8521 gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat aactttttga
     8581 acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac cgcagcacta
     8641 gtcagaaaga gtttctttct catagggaat ttcctccttt acttctttat agtaatatat
     8701 ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg aaaagagagt
     8761 gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat agtttcctcc
     8821 atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac tataagtctt
     8881 tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt tggctagagc
     8941 caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc caaaattata
     9001 ggcttgaaca gctgtccaga tatctacacc cttcttctgc gccagataga gattgcctgt
     9061 cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt tggtggaacc
     9121 acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt cagtataaat
     9181 catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaata tttctcgcac
     9241 catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag ctttatagcc
     9301 agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca ttatttactt
     9361 tggatatcct cgatattttt gattaagata gagtaggttc cattttcgtt ttggataaac
     9421 tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat tccatttgat
     9481 aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat ttcatcaaat
     9541 tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg agccgtcaga
     9601 ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct ttcttctagg
     9661 ttgttgaaaa tagctgattt gaccttggat tgaaattgaa aatcatctgt gttaaaagat
     9721 tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg agaaatctta
     9781 ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt gtacttgatt
     9841 cgtttttcaa tcaggtgata cttgctactc tgaagattga ccaccaaggc ctcatcagct
     9901 cctgttccaa atccaggcag gttattctga gttagcttga ttggattatc aacttctcct
     9961 ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg ttctacacct
    10021 tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga aatgctaaac
    10081 tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc tgtaatatga
    10141 ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga atacacatgt
    10201 tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa cttatctgct
    10261 aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt aatataaatg
    10321 tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt tgactgcact
    10381 tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa tgatgagttc
    10441 agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg ctgctccgat
    10501 acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat ttttatttag
    10561 ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta caaccttagt
    10621 cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga aatcagggtc
    10681 ttgcaagaag acatctgcca tagccttgct gttcttgata acattggcag catattcctt
    10741 gaaagctgga tccaaaactt ctttgaagga aactgcctta gcagccacaa catgctccaa
    10801 aggaccaccc tgaataccag ggaaaatagc tgaattgatt ttcttagcta aatcctcatc
    10861 attggtcaaa atcaaaccac cacgaggacc acgaagggtt ttgtgggtcg ttgttgtagt
    10921 gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc cagcgatgtg
    10981 ggccatatca accataagct tagccccaac agcatctgca atttcacgga attttgaaaa
    11041 gtcaataatt tgagaatagg ctgaagcacc tgctacaatc agttttggtt ttacttcttg
    11101 ggcttgtttc aagatagcat caaagtccaa gagttctgtt tcaggatcca cactataaga
    11161 aacaaagttg taggtttgac cagagaagct aacaggagct ccgtgggtca agtgtccacc
    11221 tgctgctaaa tccatcccca taaccgtatc acctggctca atcaatgcca tgtaagccgc
    11281 acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac cgaaaatttc
    11341 ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc caccataata
    11401 acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt gagctgccat
    11461 aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt gttggcgttc
    11521 ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat catctttgtc
    11581 aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat tttacaataa
    11641 gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa gtatagccaa
    11701 ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag cggataaacc
    11761 cataaccaca tcttctggct tcttgttcca acccttgtag taaactttta ccgatacctt
    11821 gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct ttggaataga
    11881 gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct gcatcctcat
    11941 agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta gccgtttcct
    12001 ctagactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct ttcacatctg
    12061 tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg caaccgagca
    12121 agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc tccagacaaa
    12181 tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttctagacc cagaacctct
    12241 tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc tgagatattg
    12301 gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat agggtgactg
    12361 ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac tcggtcattg
    12421 gcttcgagaa taatggtcaa ggaacctggc aaaaaggtct ctacaagttt ttgtagataa
    12481 gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt gagattgagt
    12541 gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt ttcatctaag
    12601 gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc accattttcc
    12661 aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac caaattggtc
    12721 tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg gaacactttg
    12781 accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat agtcttttgc
    12841 atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga gagctagatg
    12901 aggctccgaa tgcaaaacat tcaaacctac ctctgactca tcttcacgag agatataggg
    12961 tggattggat acaattatat catatttttc agaaatttct gcaaaacaat cagatttttt
    13021 aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta aggcctcttg
    13081 agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag cgagagcaat
    13141 agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat tttcagttag
    13201 aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt catccacctt
    13261 taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct tgtgagctgc
    13321 tagttgctgg taaatatctt ctataaattg tttttcttcc tctgttgtca cctcctgctg
    13381 gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga caaaagagag
    13441 gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa ataattgagc
    13501 taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag caccaaggca
    13561 tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag ggtcaagccg
    13621 atacggtggt ctgtgacacg gttttgtggg aagttataag ttcggatccg ttctgaacgg
    13681 tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc aatctgagca
    13741 aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcgcggtt cttctgctgg
    13801 gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat acgaacggca
    13861 gtcgcaacct tattgacgtt ctgtccccca gcaccagagg cgtgatagat gtcgacacga
    13921 aggtcttttg gatcaatgtc gtattcaacc tcttcaactt ctggtataac aagaactgtc
    13981 gctgtcgaag tatgaacacg gccttggctt tctgtcacag gaacacgttg cacacggtgg
    14041 gcacctgatt catacttaag cttagagtat acagactgac ctgaaaccat agcaaccact
    14101 tctttaaaac caccgacacc attcatagag gcttccatga cttcaaagcg ccaaccttgg
    14161 gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc cgcttcgtct
    14221 ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg atcctttgga
    14281 aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc atctttgagt
    14341 tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat catctcttcg
    14401 gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac ggtgtcacga
    14461 ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac gacatcaggg
    14521 tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag ttgatcatag
    14581 atgttcattt ttcttcattc tccttattga tttcaggggt aaaataatgt ttacggcaaa
    14641 ccgagatata ggtttcatta ccaccaatct ggatctgttc tccatcgtaa acgggcagtc
    14701 catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag atggtcttga
    14761 tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac aattcattgc
    14821 gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc acaacacgag
    14881 ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaaa acacagtaag
    14941 gtttttctgg taggtctcgg atatagccaa agatatccgt tgtttcctca atcgcaaggg
    15001 cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc gtatccagag
    15061 ccgaggtcat aatcacaaca ccttttcctt gctcctcgta gttataggcc actttgagaa
    15121 tctcaatcgt tttaccagag ttcatggtcc cataacgata gtacaactgt gccatgtttc
    15181 ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat tttcttaagc
    15241 tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga agctattatg
    15301 ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa agctcttgct
    15361 aaggaagtaa cggaagcggt tgttcgcaac actggagcac ctcaatctgc tgttcatgtc
    15421 atcatcaacg acatgccaga aggaacttat ttcccacaag gggaaatgcg caccaaataa
    15481 gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcaccc attgaagaaa
    15541 tagtctaaat ttgttacaat ttgaaaagag acttggaaaa ttccaagaaa agagcaatta
    15601 attaaaggaa acattatgat tacacgtgaa tttgatacca tcgctgctat ctctactcca
    15661 ctaggtgaag gggctattgg tattgtccgc ctgagcggaa cagacagttt tgctattgcg
    15721 caaaagattt ttaaaggaaa agacttgaac aaggttgcca gccacactct caactacggt
    15781 cacattattg atcctctgac tggtaaagtc atggacgagg ttatggttgg ggctatgaag
    15841 tctccaaaga ccttcactcg tgaggatatt atcgagatta acacccacgg tggtattgcg
    15901 gtgaccaatg agattctcca gctagctatc cgtgaaggag ctcggttggc agaacctggt
    15961 gaatttacca aacgtgcctt tttaaacggt cgcgtagatt tgacacaggc cgaggcggtg
    16021 atggatatca tccgcgccaa gacagacaag gccatgaaca tcgcggtcaa acaacttgat
    16081 ggttcccttt ctgatcttat caataatatc cgtcaagaaa tccttaatac acttgcccaa
    16141 gttgaggtca atatcgacta tcctgagtat gacgatgttg aggaagccac tactgctgtt
    16201 gtccgagaga agacaatgga gtttgagcaa ttactaacca agctccttag gacagcacgt
    16261 cgtggtaaaa tccttcgtga aggaatttca acggctatca ttggacgtcc caacgttggg
    16321 aaatcaagcc ttctcaacaa cctcttgcgt gaggacaagg ctatcgtaac agatatcgct
    16381 gggacaacac gagatgtcat cgaagagtac gtcaacatca atggtgtacc tctcaaattg
    16441 attgatacag ccggtattcg tgaaacagat gacatagtgg aacaaatcgg tgttgagcgt
    16501 tcgaaaaaag ccctcaagga agccgacttg gttctactag tgctaaatgc cagtgaacca
    16561 ctgactgcgc aagacagaca acttcttgaa attagccaag ataccaatcg cattattcta
    16621 cttaataaaa ccgacctgcc agaaacgatt gaaacttcga aactacctga agacgttatc
    16681 cgtatttcag tccttaaaaa ccaaaacatc gacaagattg aagagcgaat caacaacctc
    16741 ttctttgaaa atgctggctt ggtcgagcaa gatgctactt acttgtcaaa cgcccgtcac
    16801 atttccctga ttgaaaaagc agttgaaagc ctacaagccg ttaatcaagg tcttgagctg
    16861 gggatgccag ttgatttgct tcaagttgac ttgactcgta cttgggaaat cctcggagaa
    16921 atcactgggg atgctgctcc agatgaactc atcacccaac tctttagcca attctgttta
    16981 ggaaaataag aaaaatccat gatccttcat tcggtcatgg attttattgt ctttattagt
    17041 aatctggtct taagacacct gttacagttg ccttggtcgc ttcgtagtcg ccatctacga
    17101 caaccttgat aatgcgttta gcatcttctt ctggtgctgg aacaagaggt agacgagttg
    17161 gtccagcttc aaatcccatg tagttcaaaa ctgccttaac tggagcagga cttggataag
    17221 agaagagagc attaacctta ggaatgaatt tacgttgaat agctgcggct ttcttcatat
    17281 cactttctgc aatggcaata aacatctcgt gcatttcatc cccatttgta tgagaggcaa
    17341 cagaaataac cccatccgcc ccaaggttca tggcatggaa agcatctcca tcctcaccag
    17401 tatagaccaa gaactcttct ggtttgtgct caatcaagta agccatatta gccaagctag
    17461 tacattcttt gacaccgata atatttggat gatcagccaa gcgaagcatg gtttctggag
    17521 ttaattcaac aaccacacgc cctggaatgt tatagataat aattggtagg tcagaagcat
    17581 ctgcaatggc tttaaaatgc tgatacattc cttcttgaga aggtttgttg tagtaaggaa
    17641 caatagcaag accagcagca aaaccgccga attccgctac ttctttgaca aactcgatag
    17701 agtcacgcgt atcattagta cctacacccg caatcaaagg aactcgtcca ttgacaatct
    17761 tttgtacagc cgcaaataac tccaactcct catcgtgggt caaagttgga ctctcagcag
    17821 tggtccctgc gagaagaatt ccatccgtat gatggtccaa taaatgctca atcaaggctg
    17881 gaatagcatc aaagttgatg gaaccaccct cgtggaaggg agtaataaag gctgtgatga
    17941 ttttacactc ttttaaatct tgataagaca tgaaaacacc tctctatttc aaagaaggag
    18001 ttcatctgaa ctcctaaacg atatgactat tttaattcaa atttcaattc agctgttgga
    18061 cgaaccaatc cacgttcatg aagagtttca gcaatctgaa ctgagttcca agcagcacct
    18121 ttgagaaggt tatctgaaac aacccacatg tgaattcctt tttctgcatc caagtcttta
    18181 cggatacgac caacaaaggt atcacgtgaa ccaactgcat tgatggcttg aggatagatt
    18241 tgatgaacta catcatcttc aagaacagca cctgggaagg atgcgatagc tgctttgact
    18301 tcttcaattg gagccacttc ctttgtttca atataaactg actcagagtg agctgacaag
    18361 actggaatac gcacacatgt cgcagatact gcaatgctat catcttccat aattttctta
    18421 gtttccttgg tcatcttcat ctcttcgtac gtgtaatcat tatcagtgaa gacatcaatt
    18481 tgtggaagag cgttaaaggc gataggataa tgtttcttgt caccacctga aggcaagatt
    18541 tccgcatgca aatcacgtgg tttcactcca tcattcaaga cctcacgaag ttcacgttgt
    18601 gtctcaagaa ttgctcccat accagcacct gaaacggctt gataagttga aacaatgata
    18661 cggtccaagc cccatttttg gcgaaccggc tcaagagcca ccatcatttg gattgttgaa
    18721 cagttagggc aggcaatgat tccgttgtgg gcatcaagtg catgagcatt gacctctgga
    18781 acaaccaaag gaacatctgg attttgacgg aaataagatg tattatccac tactaccacg
    18841 ccagctttta ctgcgtatgg tgcatactta gctgatgtcg aaccacctgc tgaaaagaga
    18901 gcaatatcaa ctccttcaaa agctgtttca gtcgtttctt caatcgtaat atcttgatct
    18961 ttaaatttca atgacttacc tgctgaacgt gcagaagcaa ggtaacggat tttatcgatt
    19021 ggaagtgttg attcttccaa catttttatc atctgagcac cgacagcacc tgtcgcgccg
    19081 actacagcaa ctgtatatcc cataaataac ctctttcgga attttctaaa aatttctata
    19141 atagaagtat tatactactt tttccatgaa ttgcaaagct ttttcatcat tttttggaaa
    19201 ataaaaatcc ccaatcgcta gactagggat taagaggcat cttcatgtga tgagcaggtt
    19261 cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa tagtagcccg
    19321 aagactacct atcgactcat cgcatctact attctactaa agagaatgac ttttgtcaac
    19381 agacgaaact ctttatactc ttcgaaaatc tcttcaaact tcgtcagcgt cgccttgccg
    19441 tatgtatggt tactgacttc gtcagtttca tctacaacct caaaaacatg ttttgagctg
    19501 acttcgtcag ttctatctac aacctcaaag cagtgctttg agcaacctgc ggctagtttc
    19561 ctagtttact ctttgatttt cattgagtat tagttttatt tacacaggtg cataagaaat
    19621 atattggaaa aattgggggc agacataaca aaaacccttg taaatcaagg gcttttctgt
    19681 ctatttaatg ctaattgccg ggattgaacc ggcgacctca tccttaccat ggatgcgctc
    19741 tgccaactga gctaaatcag cttacttaag aagtatacta taatcagaaa aacttgtcaa
    19801 gtttccttag aaattttcca taggaaaaag ccaggtaaga actacctagc ttatcttctt
    19861 ctatttactt aaatcaattc gacgaccaat tttaccaata ataatcgctc caataatcaa
    19921 tgaagcaaat tcaccgattc ctgttgtaaa ccaagtaagg aagaatggta attctgctac
    19981 aatatttaac tctgcagcga tagtaaacat ggaaattgaa aagaggattg aaaagaagaa
    20041 atgatctttt cgaatcaatc cgttaaagag gtaatccttg ctatattttg caaaaagcca
    20101 aacacctaaa ctgaggaata ctaaggttga accaccacca acaaagacat ctagcagtcc
    20161 gaagctaaag aaattagcaa tcatacaacc gatggtaact ccgatgatgt acttaggatt
    20221 gtaaaaagcc ataaagttca tcatttctga aatacgaaac tgataagcac catagctgat
    20281 ggcatttagg ggcggtgtga cagtcaaaac gacgtagata gcagcgacga ttgcaatatc
    20341 tgcaacatca cgaatagtta attttttcat cttttctcct ttggcggtta tccgcgtgta
    20401 atatgcttgg tgaaagaagc taagcaccaa gggttgattc attcaacctt actagtatag
    20461 cacaatagcc tgctttatgc tatacttaaa gcatgaaaaa acctattcaa aaatttttta
    20521 acaatgaaat cttagcctat ctcttttttg gccttgcgac aactctagtt tcgattctct
    20581 cacgactagt catttatcaa ctaagtcatc aggaactcct tgctacggcc ttggcaaata
    20641 ttatcggtat cttatttgcc tttatcacaa atgatacgat tgtatttaag caaaaaaaga
    20701 aaaatagact tatccgttta gtgaaatttt ctcttgctcg cctttctact tttctgttag
    20761 acttgttttt aacttttctc tttgtaaccc aatttcctca catcataggg caattcgtaa
    20821 ctgaaaacat tgataagata aatgctattg aaacaataat tgcacaaata ttcattatta
    20881 tcatcaatta tatcttgagc aaggtctata tttttagaaa ataatgctcc atttatgagc
    20941 cttttaattg ccttctataa tgatttagga tacaatgaaa cacgaaacat tgaaaggaaa
    21001 acagtatgtt aaaaaatcta aaatcgttct tgcttcgagg aaatgttatt gaccttgctg
    21061 tcggtgttgt cattgcctct gcttttggtg ctatcgttac ttcacttgta aacgacatta
    21121 tcactcctct tattttaaat cccgctttga aagctgctaa agtcgaacgt atcgctcaac
    21181 tttcttggca tggagtcggc tatggtaact ttttaagtgc tattatcaat tttatctttg
    21241 tgggtaccgc cctcttcttt attatcaagg gcattgaaaa agcacagaaa ctgactggca
    21301 taaagaaaga aaaaactgcc gaaaaaaaac caaccgaatt ggaagtcctt caagaaataa
    21361 aagctctcct tgagaaaaaa taatcgatta aaaggatcta gcgcaaagct aaatcctttt
    21421 ttctttactc tttgggtaac ttgcctgctt tttcaagcat ttttttgata agataaggca
    21481 tcttaacatt ctcccgccct tttttctcaa tcagtttttt cacaaattct ggcatttgta
    21541 aatcttcaga ttcagctaaa atgtttttcg tctcgtctga aggaactaac tcatcaaagg
    21601 tctcttcttc tgggagaaat tccttaaact cttgattttc attgactcta actgtattga
    21661 ccaaagcatc aatcaaacga gaatctgtat ttggcattgg tggacgatgg tagtttaccc
    21721 caaattcctg gcataagtca taacattcta catcattgtc aaacaagacc tcaatatgct
    21781 cactgatgaa actaataggt acaaaaatat aatggtctgg atgttctgtc tgttctctga
    21841 gatactccaa aacatctggt ttaatccatg gaataccaat atcactctca ctctgccaag
    21901 tgttggtata ttgttctgaa ctcaagccca gtttttcagc gactagcttg ctattttcga
    21961 aaatttggtc tatataagga tcaccaaagt ccaaggcaaa aatgggcaca ctatgggctg
    22021 aaaagatgac tttaaagctg tcttgcttta cttcttcttt taaaatctta gcaatttcat
    22081 ctgcccaata gtttaagagc gcttcttcct gataccagtc cttaatgacc aaaaattgaa
    22141 tttgtttgct ttctaaaaat ttttcatagc ccatgacaga gtagaaagaa taatggggct
    22201 ccaaaatcaa gcaaatacac tgttcaattc cgtctgcttc catttgaccg atcacatctg
    22261 gaataaaggg actggaaaac ttattagcaa agtagacact gtattcattc cccagcctag
    22321 cttctaccaa ggcaacctct tgacgggtaa ttttttgcag aggcgtgcct ccaattcgta
    22381 cataattatc atagagagtc tgaatctcgt ggtcttgggg tctcacccca cgacgaatgt
    22441 ttgtaaagaa ttctgctact ccttcaaaac taatctcctc tggagatcca aaggtcatca
    22501 ttaatatggc ttttttcatg ttatcatcct tatgatatta ttttctctat ccattctatc
    22561 atgaaagaaa aaaatagtaa acgtttccta cgtctactat ttcttttgct cttttgtttt
    22621 tttatctcgt cttataatta ggatgataag gacaagaagt aagaggacga taataaggag
    22681 tagaaaggct aggatgtaaa tccaatggct gggaattccg tgatcgaaat accgtgttcc
    22741 tactgcttcc ccactttcat cctgtgctac tttcaccggt gcatccgtta ttttagctaa
    22801 aaggatatgt cgtccattag ttatgttaag gaaacaggtg cttaataaaa caatcttgtc
    22861 cgttgaggtc aaggaaacat ctcgcttgta cttggcttta cttagcagat attgatagta
    22921 agcctggtgt tcctcatcct tggaactcaa ggttcgataa atctccgtgt cataggcatc
    22981 cacttctaaa atcccaaaaa tttcaagacc acgttctcga ccattgtagt agatagaacc
    23041 gtagcgatgc tggtcgaaga attccttatc agcaaatttc ttaatctcac cgaacatagc
    23101 ccctgaagcc atagagtgtc cgtagatgat cgtattaaaa tcagtaaagt tgggattaaa
    23161 gcgatagtcg agaaaaattg atcccgttat cgtataatcg ccaaaggcat tgcggtcaag
    23221 gtatttgaca ttatcctgac tttgtagaag cggatagtct accttggtcc catcaaggct
    23281 aatccaaccg caaacatctt tgttcaagtg ctgtagggtt tcaaaacctg tgctcgaagc
    23341 atccttttca ataggattat agtgatcata gtcacttgct tctactactc tctgccaact
    23401 aaaaagagct acaaaaacac agaagaatac cagaaatacg tttttaaatc gcgctctttt
    23461 gaaccgtcat cagcactcct ttctatgcga gatttcttaa aaggaaagga ggcgggacaa
    23521 aaccgcctct tttctattca cccttagtca gtaaaagggt ctgcttcttg catttttttt
    23581 actctctctt ctacgacgta ggatcaagta gaggacaagg agtaagaaaa tcaagagcaa
    23641 gaacaataca aacaagataa ggtaccaaat ccatagtggg attgatgaga ggaaacgtcc
    23701 aagagacgag tcatcaaaga cactgtatgg aaatggtttt gatttttttg tatggaaagt
    23761 atttttaggg acggtgtctg taatctttgc gactacgata tgacgaccat tggtcacatc
    23821 gagaaaacag gtactgagta ggatgatacg atcactcggt gagagtgaga tatcccgctt
    23881 gtgcatggcg actgagagca ggtggtctag ataggcctgc tggcggtcct caccctgtat
    23941 tcctggatca tagatgttaa agtcataggc atcaacctcc aacatctcaa agatctcgag
    24001 ccctttttcc acaccattgt agtatatact accgtaacga tgctggtcaa aaaattcctg
    24061 atcagcaaac ttagccacat caccaaacat gaccccattt tctacgtggt gcccgtagat
    24121 aatggtatta aagtcttcga acttaggatt atttcgtgca tcgagaaaga tagcgcctgt
    24181 cgctgcaaac tcacctttgg agtccttgtt gagatacttt tcattgtcct tggcttggac
    24241 taagggatag tcgatattgg tgccatagac attgatccaa ccgaggactt cgggattgag
    24301 ttcttggagt ttgctgaagc ctgaaaaact ggccagctca tcctgttgcg tcgtgacagg
    24361 tcgataagct tcgtactcac ttgacgaagc taaggagtag acttggttgg aatcccaaag
    24421 ggcgtagaaa ccaaagagaa agatcaaagc tgcaaaaatg agcagcaagt gattgatcac
    24481 cccatccaca gcaagaacga gacgcctaga cagactcttt tttggtttct cacgcttggt
    24541 tttcatcatc tgcccccagc cgtttaggct tctctacgtt ttttagacaa gacaacaaat
    24601 ccagccaaac caagaccaat catcaaaatg aatggaaggt tatcaatcaa gagaccagta
    24661 ggagtaacgt cgtcgatttt gttagtaact ttgttgtcgt ttttcttttc acctatgagg
    24721 atatctgtta atgtaaaatc tacatttttt tgtccttgag atgtttgttc tgcaccattt
    24781 gtagtataaa ttgatgaatc tgtataacct gctactccag tttcagttac tgtatattta
    24841 gaacctgctg gtagttgttc aactgtaaat gtttcaccat ctttaagagt aaaattgtac
    24901 tcaactgtat ctgctggggt cactactgcc aacacctctg acttagatcc atgttttact
    24961 ataatattcg taacaggggt ttctgctgtt ttatttgtac ttggaagttg aatcttgata
    25021 tggaattgga aatctcttgt tttatcccct gaagctccat caactttttt agtaattgtt
    25081 aatgctttcg cattggggtc tacttgactc ggatcatcag gattaggctc cttacttgcg
    25141 tctttggtat atgtgttatc aaataaatta taaacgcctt gttcacttga ttctacttta
    25201 ggggcgttag atttattatt ttccttaaag tatactgatg aaatatagac accaccattt
    25261 actttattct taacaataac gtgcatttca tatgtacgtt tgtcgtatct catggcatca
    25321 attgttttac catttttggt aatcgcctgc catccagttt ttgcttccgc tacatcataa
    25381 acgtattcac cagcatggcc ataagcaact cccgaaaaaa tgtcttctgt tgctttttga
    25441 atcttatcag cagttgggtg atcattttta ttgtattcta catttctatc tggaattgca
    25501 actccggttt gatatggcgc accgttagaa gattgtcctg ttttttctgt aaacttaaat
    25561 gtaaatgtcg ctgttggtgt tgttattccc tctgcaatat tcaacgtttt attaatcttc
    25621 acaacagcat tattttcacc atttgctttg gttattgctg aattatcatc cgcaaaagtc
    25681 gggacacctc tgaatacgga caaagcggtt atagctgcaa tgcttgcagt gaatagcttt
    25741 ttaaagaatg tttttttcat gattatttct tttgtttttt tattttcttt tttcattatg
    25801 atcatcaaaa gcctcgtctt ctaatgactg ttacaacttt gccttgagta tcctgtatag
    25861 ggatggttcc aaaagcacga ctgtctacag ccgttgttcg attgtccccg aggacaaaaa
    25921 gttgtcctgc tgggactttc atcgggaagg ttgccccttc cttatagagc agcgtttctt
    25981 tgtagatatc ttgctcttgt tgaggagaac cgttgatgat gagaccattt tcgtttatat
    26041 cgattgtact tccttcggtt gctatgacac gcgccactct ttccttacct ttataactat
    26101 agactagcaa atcaccaatc gaatagcgtt tatccaacct ataatagacg accaagtcgc
    26161 catcttttaa ggcgggcttc atgccatcgt cattgtatct taataatcca aagacgaaaa
    26221 agtaaagggt ggctagtaca aatccaacca tcagaagttt actgactaag taaaggatat
    26281 ctccccagac actcggcgga gacttatacc gattgacttg tgttactggt ttcttatgtt
    26341 tctttttaag cagcatcact tcctcctatt caccacaagg tgaccaagta agatgataaa
    26401 gaagatccct cctagaggaa gaacgactcc aagcacgaga gtgctactca agaagtcaat
    26461 tcccgtttca ggtacgctgt ttttattatt cgtgactgtc gcagacttat ttgcatcaag
    26521 agttccttct tttttatcat aggacacctg atacccacga gacgaacttg cttcttcttc
    26581 gatactataa cgagcattta gaggaaggtc gagaatcttg atggttttat ctttctttag
    26641 atcaactgtc gccttaccat tggtgaattg tagcgttgtt ttttgattat ttactattgc
    26701 actatacgat ccattcaatg gtttattttg cgcatccttt acgttaatgg taatcttaaa
    26761 ggattgcaga agattagcaa aagcacctgt aacttttttt gtgactgaaa gtgtcggaag
    26821 tctgtggttg gtgacgattg tttgaacatc ctctgacaaa gtcccctctt gtttttcata
    26881 ggtgacatga tatcccgttc tagagttctc tacttcttcc accttatagt gggtatcacg
    26941 aggcagataa ctgagggcag tttcctgact atttttgaga gaaatctgtg ctttcccgtt
    27001 agtcactgtt gtattcccaa acttgccgtt aatcggcttg ccatccttat ctgaaagggt
    27061 aacattaatt gtgaaagatt tattaggtga ttgttcacct tctaggattt tctttacggt
    27121 gagacttgga agctgtcggt aaataacttt gaaggatggt ttctctttcg tacctgtctt
    27181 ttgaacttcg actgtgtatc ccggagcgtc tggtgctttc agttcgtagt catatccctt
    27241 agctaccttt gcaaaactag tattttcagt aaaactattc gtttgaactg gactagtgac
    27301 ctttcgatag gaatccttta tacttccatc tttcttttgg tttaagttta attcgacact
    27361 aggtggacga tttgctgatg gatttgattt tccatccaca cctttccact caatctctac
    27421 aggaaccgtc aatggatctg acggcttgaa agtgggcttc tcagaatagt cttttatttt
    27481 ggtacgtgag gtcccaatac cataggaata ggcaactttt gcccccttgt tggagtagag
    27541 tttagtagca tcggcttctt cggcatcatc actagtaagt gtcttatcac ccgcaatcgc
    27601 atcaaatgcc tcttggctag aggtgacagt aaacttgaga acgtacttgg cgtcatcctc
    27661 caaagtgtaa ctcggattaa acttggctgt tacttccact aatccctgtt cgttcttctt
    27721 agtttcaatc gtaacttgat tgtcattcag ttcttgctcg ttaccatcct tgattttgac
    27781 gacacgaagg tgtgaagcat caccaggtaa cagctgcacg tacttggaca agacatctga
    27841 tatagttaca tggtgtacgc ctagaggtag aattttatct gtgatttctt tgaatttttg
    27901 ttgcaagtca ttttcattat tggcagaaaa tatttcgttg gggattccag aattataacc
    27961 actgatatat cctttaagag atgtgatact atcgtttgaa cctatatatc tgaatttgat
    28021 tgaataaaag ccatctattt ttggagctat taaactagat atattcagca ttcctctctc
    28081 taaaccagag gtaaaccaat atggagtatc aatcatacgt cccacatttg gattagaata
    28141 atagttatat attgttctcc cactattaga ctcgtaatac atattagctt cgccatctga
    28201 cagcagaata actacttttt ttgccccagc ccttgcactt tgcaacaatc tttgagcttc
    28261 agttaaccca gcatttatat ttgtcccagt gccaatgccc gcgtccatac cataagaacg
    28321 actagagtca gcaattgtta acgaactaac aatatttttt gagctattag aatccgtgct
    28381 ccaagatact aaagttttag catcatcata tgaagagata tttgaatacc aaccagctca
    28441 atttggccaa gttccatatt gataactcag ataatattca ttataataac ggccattata
    28501 ctgattatca atctttccgg caaaaccaac tatagacaga cggttttggg aattagaaag
    28561 aattgtatca atgagcccct gacgaccatt cacacctttc agtgtatgtt ttagtgcttc
    28621 aatcctacta atgtatcgtc tactagagta agaccacaca tctcgctctt ccatactccc
    28681 tgaaaaatcg gcaaccaaga ctacatccaa gggttctgac tgggtctccg tctgggtctc
    28741 cgttcccagt ttagatgtga tatccagtga caactcatac tggtcttctt gccctgatat
    28801 cggagtaatc gttttgtgca gagttgtctg aggttcagtt gttgaatctg cacgtaaaga
    28861 attaattggt gcacacaaaa aaagaatagc gagaaagata actaaactac tggtaaaata
    28921 ttgaatcttc ttaaaatcat attgaacgtt catgctatct cccttgctag aatatgtttt
    28981 aatctgatac tatataaatc tgagacttcc ataagataat tgtataataa tattaacttc
    29041 gtgtcaatta atgtgtttga aaacatgtta ttataaatta caaaaaagta tgattcttct
    29101 ttgtttttca actttttctg tggtaaaatg gaaaaaatag taaaaaattt cataaaataa
    29161 agatgcatat atttattcta atcgctcgaa aatttctttt gaaagtcttc tgaatttgaa
    29221 ttattatatt ttttcaaaat tcataaaatt tctcaaatca tatttttccg aagttttgta
    29281 ttctatttta tgataaaaaa ggagtttttt tatgacttat ccaaatctct tggaccactt
    29341 cttaacctac gttaaggtca acacgcgctc tgatgaacac tctactacta ctccaagtac
    29401 acagagtcag gttgacttcg caacaaatgt cctaattcct gaaatgaaac gtgttggact
    29461 gcaaaatgtt tactatctac cgaatggttt tgctattgga accttgccag ccaacgatcc
    29521 gtctttaaca cgtaagattg gttttatatc gcacatggat actgctgatt ttaatgctga
    29581 aggagtcaat ccacaggtaa ttgaaaacta cgatggtggt gtgattgaac tagggaattc
    29641 tggtttcaaa ctcgatccag ctgacttcaa gagtcttgaa aaatatccag gacaaacgct
    29701 catcacaaca gatggaacaa ccttgctagg tgctgatgac aagtcaggaa ttgctgaaat
    29761 tatgacagcc attgaatatt taactgctca tcctgaaatt aagcactgtg agattcgtgt
    29821 tggttttggt ccagatgaag aaatcggtgt tggtgccaat aaatttgatg cagaagattt
    29881 tgatgtggat tttgcctaca ctgttgacgg tggtccacta ggtgaacttc agtacgagac
    29941 tttctcagcc gctggtgctg aattgcattt ccaaggccgt aatgtccacc ctggtactgc
    30001 caaagggcag atggtcaatg cccttcagct agcaattgat tttcataatc aacttccaga
    30061 aaatgaccga cctgagttaa ctgaaggtta ccaaggtttt taccatctaa tggatgtgac
    30121 aggtagtgtt gaggagacgc gtgcaagcta catcattcgt gattttgaaa aagatgcctt
    30181 tgaagcgcgt aaagcatcca tgcaatctat cgctgataag atgaatgaag aacttgggag
    30241 cgaccgtgtc actctcaact tgacagacca gtactacaat atgaaagaag tcattgaaaa
    30301 agatatgact ccaattacca ttgctaaagc cgttatggaa gatctaggta tcacgcctat
    30361 tatcgaacca atccggggtg gaacagacgg ctctaagatt tcctttatgg gaatcccaac
    30421 tccgaatatc tttgcaggtg gcgaaaatat gcacggacgt tttgaatacg ttagccttca
    30481 gactatggaa cgtgcagttg ataccatcat tggcatcgta gcttataaag gctaaaaaga
    30541 cgaggtggct cagctacttc gcctttcttt ttattctact ggtttttctt gatttccagt
    30601 agttgtagaa gattctgttg tttcattttc tgaagttgat tcagcaggtt tagaatctct
    30661 tgtattgctt ggtttgtttt catcgctagc agtttcaatg ttagattctg cagttgcgtt
    30721 tggttgattc tcagcactgg tgttatcacc atttgcttca gcattttttg ctggacttgt
    30781 ttcttcactt gcgctagctt ttgactggat ttgatgattc aaaactagaa tagcttttgt
    30841 cgattcaagt aaagctgttt tgtctttact attagcagaa agttgatcta ataatgcatc
    30901 caccttatca aagtccgcat cagatccatt attactttct aaataagagt gaagcgacat
    30961 gagaatatcg tagggttttt gatagagtac aagtgtctga ggatcttgct cagcattttc
    31021 cttttcttgt tgaagggcgc tagcgatacg agtcaagaca tcttttacct gactgtttac
    31081 ttcatccaag tctgcatcag ccttgtttgt ggcagctttt agattttcta cttcttctgc
    31141 caaggattgt ctgattcctt cttcatggat ttgttccaat agttgatttg ccttgctcaa
    31201 aagactttct acttcttcct tgctatctgt cgcagattat tggttgccat ctaccatgta
    31261 ctcctaaaac aggagagtta taatccaaga ttacaaggcc ttacagaaat aagaaatcca
    31321 gataagacaa tgttcgtcca agacgctatt cgcttcgcac agcagcacgg attcaatatg
    31381 ttttaatttt aaagtttagg tgtcaagacc tctttttagt gtgcccaaaa tttagagaag
    31441 taatcaatca actaactttt atttttttca aactttcagt aaactgacct aaagctaact
    31501 caatctgtct ttgtagatgc ttctgctatc agctagaagt tgatctactt ttaccaagac
    31561 tgccttctca tcaaaagttc caggttgata gttggattgc agggatggaa tcttgttttt
    31621 caaagccgct tcatatccct tagtttgaac cttgatgtag tgattgtggt cgctatgagg
    31681 aatcacaaaa ccttctgaat cttcacttat aattcgattg gcatcaaaac catgaccatc
    31741 ttcttcctca tggtggacat gtagtgacgg attacttaat acagaactag aagaacttcc
    31801 tacctcttcc gtgttagagt gtgatggggg attgttaaga gatgacttag gaatatagtg
    31861 atagtgatcc ccatgtctta ctatataagc atcacctgta tctctgacaa tatcattagg
    31921 gttaaagaca tatgtggctg ctaattcacc tgccgacaag tcactctcag gaatgaaatg
    31981 atagtgacca ccatgtggta ctatcgtaga ttgaaataga atatgagcaa attgataagg
    32041 ggattttaaa gtaatttcta acaatgattt agaaactatg atgtgctatt ctaaattcaa
    32101 ctcactatat ataaccatca tcggtagtat aacgtccctg taattttgct acagatactt
    32161 ctgcactagc tcctttatcg tctttaccat gttcttgttt ttggcgattg atttcatctt
    32221 ttgttcgtac attttctgca tgagcttgat ctttaaggta aacataatac tttccatcta
    32281 ccttaataat atatcctccc ttaacctaac tgacgatatc ttgatctttc ggctgatagt
    32341 tgggggcttt cattagtagc tcttcactaa agagcgcatc aaaaggaact ttaccattat
    32401 agtagtgata atgatcgcca tgagaagtta cataaccttg atctgtaatc ttaataacaa
    32461 tttgttttgc ttgaattcct tctttttgac taacctagtc tggagtcaaa ttttcagtct
    32521 tcttagtgtc tttattactg tttacatatg aaacacgatt tttatctgta ttggcctgtt
    32581 agctatgttg gttcagagca taaacacaca gacttaagga aaggataaca acagatccag
    32641 ttgctatata tttcttttta aatttcataa ttacctcatt tctataatta tttatatgat
    32701 gtcttcatta ttaaatgatt aaataaatta attaaccagt taattaacta gtaaatattc
    32761 cacctctttt taagttgtat gtcaagaaat tttatatatt aataataaaa tgaaattctc
    32821 ccaaagtcag agttttattt ctaacttttg agagaacttc atttttgatt cagacttttt
    32881 ctactgctat tccttacgct atgagatcag ataaattctt ttttatcact tctccacttg
    32941 gcaatcttaa ttcaatcgtt ccatccatat tgaatataac actatctaag cctaatccgt
    33001 aactagctgt aaatttttct aatttttctt gtacaggatc tactgctgga gcttcctcta
    33061 atgctggatc taacataggg tcactcccca cattcccttc tggattcaac attccattat
    33121 ccgttgagtt ttctggtttt acaggttttt cgtttggtgc ctctggtaaa gaatctgctg
    33181 gtttattttc accatttcct tgaggtgctt ctcctgtaaa atctgccata ttctttttaa
    33241 tgacttctcc cgatggtaaa tataattcaa ttgttccgtc catattaaac aagacatttt
    33301 ctagcttcat cccataactt tcagcaaatt ttgctacttt ttcttgtaca ggatccactg
    33361 taggaacttc ttctaacgtt gaattactag tactattccc agtttcagaa agtttttctt
    33421 tttctacctt ctcactagtc tttggttctt ctaccttttc atcaagtttt gagttttctt
    33481 gtgctttatt ccttttaaat tgtggtagaa tacttggttt atcagtttga ttttcttttt
    33541 ccaagatagg tacttccaca atataagtcg attgattgtc caaataagca tttgccatga
    33601 aggttacagg aattttattt ccggccgttc tggttgttcc ttggtttaat ttcggaatcg
    33661 gtaatttaat ttcaccaact ttatagttat tttctaaata agcatttcca tgaaattcat
    33721 caaacactct gactaaagca tcagttcctt taggcactgc aaattgaggg ttcactctta
    33781 aataagtatc ccctgcatgg aaaggataga aaatcgtttg actggccatt ttgtaagcta
    33841 aagaggttgg aactgtaaat gtaccatcat aacttacttc tggataatct tttgaagcga
    33901 tagtatactt aaatgtttgt cctggtaaat aaggttgatc taattcaaag tttgcaatat
    33961 tccctactcc ttctccaaat actttaccag atactttctc caatactttt ccatctggtg
    34021 ttattaattt tactagcata ttgataccta attttttttc caattcaggc ggaaaactaa
    34081 aagaaacgcg tttttgacca ttggctagag taaagttttg attattaaac gtactatttt
    34141 ttaacaaatt aacaacattc gttaattctt ctccagtata aactttattc ccttcttttt
    34201 tagcaactcc ttcttcgggt ttaaacagtt catagttact gtgagaatga ccaattccaa
    34261 ccggtttatg ttcatcaatc ggatctgcat gatggtgatc tccatgcgga taaataatcg
    34321 catttttttc tttattcacg acaatacttt cacgtttgac accatattgt ttcataatgc
    34381 cagcaatttt ttcttcgatt tttttatcta aatctttcat ttctttggca ttacctggat
    34441 aatcctgttc atgagatgac aaagaatcta atccattatg actagtttta acttcctcta
    34501 aatgtttttg cgcagcctta atttgctctt ctgtcaagtc cttcttgaag aaataatgat
    34561 tgtggtctcc gtgactcatg acaaaacctg attcatcttc agcgataata cgattagcat
    34621 caaatccgta tccatcttct tcatgtttct catgtgaagt tcctggattg attggaagag
    34681 atggagaagg tgttgctaga ctattgtttg gaagagtcgg ttgcccaatt tgatttgatt
    34741 ttggaatgta atggaaatga tcaccatgtc ttacaatata agctgtagcc gtttcttcaa
    34801 cgatatcttt tggattaaaa atataaccat cagatgctga agagagttcc ttacttgtcg
    34861 ttaaagaaga aggattgctt gaaagactgc ctagactaga cactacttca ttaggttttg
    34921 catttgtaga aactgtagaa ccagttccac tgataggcac cattctggca atcttttctt
    34981 ctaaggcaga aagcttgctg taaggaataa agtggtaatg gtcgccatgc ggaatcgcaa
    35041 ctccatttgg tgtacgactg ataatcttag cagggtcaaa gaccaggcca tctgattcac
    35101 tgtaacgttg ggcgctaggt gaatcataga gttccttcaa aagactctgg agattttcag
    35161 atttatttgc tggcttgcta gttgatcctt ttgctacaga ttgcgtgtta ttgtcactag
    35221 ctgttgaaga atagcttaac tgactcggtt gtatattttt tccagccaga tgtgctttag
    35281 ctgctgctaa ttcactagca gataaatcgc ttttgggaat gtagtgatag tgacctccat
    35341 gaggaacgat ataagcatta cccgtatctc cgataatatc agctggatta aagacataac
    35401 catcatttgt cgtatatcgt ccctgagacc ttgctacagc aacattagag ttaaccttct
    35461 cattatcttt gacatgttct tgtttttgac gattgatttc atctttagtt cgaacattat
    35521 cagcatgagc tgcatctttc aggtagacat aatattttcc atcgaccttg atgatataac
    35581 cacccttgac ttcattgaca atatcagcgt ctttaagttg atagtttgga tccttcatca
    35641 agagttcttc actaaagagg gcatcataag gaactttccc attatagtaa tgatagtggt
    35701 caccgtgtga cgttacatag ccctgatctg taattttgat tacaatttgc tcggcctgaa
    35761 ttccttcttt ctggctaacc tggtctggtg tcaagttttc acttttctga cttgactggc
    35821 tgccatctac ataagagaca cgattattgt ccttattttc ctgcgaacga tgctggttta
    35881 gtgcataggc acatagactc aaggatacga taacagctga tccagctgct atatattttt
    35941 tactgaattt cataaatccc tcatttcaat aaatgatgaa gttttttctc aacttctttt
    36001 actttattaa atagttttct aaaccggtta tttaaccatt taattaacca gtaaatagtt
    36061 tactatttaa aattactttt gtcaagtttc tgttacgttt ttctaaaaaa gagaagtaac
    36121 acgaaaggtt acttctccat aaaatatgct ccattcattt tactactgta taggaaccgg
    36181 ttgacttttt tttaacaaag ccaagagact atctacttct gctgaaatag tgttattatc
    36241 tttcgttccg agaagaagac tactttttag accagtcaat gtctccatag cattttgtct
    36301 aatactagga tctgttactt tttctagcaa ggcctccgca tctgctatct tagcgttaat
    36361 aacagaatgc tctacttgag gaatttcagc ctcatctgta gtatcttcag cttcttcctc
    36421 tgtctcttcc gtatcagtgc ttggtttata aagattatct gctgaaggat ttaaaccagc
    36481 gtgattctct ttttcatcag attcagggtg agttggctca cttacttcat catgtccctt
    36541 atcttcatca ggtttactat cttggtctgc cttattttta
//
LOCUS       DAVDFK010000019        31468 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.19, whole genome shotgun sequence.
ACCESSION   DAVDFK010000019 DAVDFK010000000
VERSION     DAVDFK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.19"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(68..1048)
                     /locus_tag="VUR04_001172"
     CDS             complement(68..1048)
                     /locus_tag="VUR04_001172"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET5341072.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMVLHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(1050..3302)
                     /gene="pbpX"
                     /locus_tag="VUR04_001173"
     CDS             complement(1050..3302)
                     /gene="pbpX"
                     /locus_tag="VUR04_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET5341073.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(3306..3623)
                     /gene="ftsL"
                     /locus_tag="VUR04_001174"
     CDS             complement(3306..3623)
                     /gene="ftsL"
                     /locus_tag="VUR04_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET5341074.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(3635..4585)
                     /gene="rsmH"
                     /locus_tag="VUR04_001175"
     CDS             complement(3635..4585)
                     /gene="rsmH"
                     /locus_tag="VUR04_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET5341075.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            4751..4945
                     /locus_tag="VUR04_001176"
     CDS             4751..4945
                     /locus_tag="VUR04_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341076.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            4961..5203
                     /locus_tag="VUR04_001177"
     CDS             4961..5203
                     /locus_tag="VUR04_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341077.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            5214..5549
                     /locus_tag="VUR04_001178"
     CDS             5214..5549
                     /locus_tag="VUR04_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341078.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(5659..6660)
                     /locus_tag="VUR04_001179"
     CDS             complement(5659..6660)
                     /locus_tag="VUR04_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5341079.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(6720..8621)
                     /locus_tag="VUR04_001180"
     CDS             complement(6720..8621)
                     /locus_tag="VUR04_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET5341080.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(8643..8936)
                     /locus_tag="VUR04_001181"
     CDS             complement(8643..8936)
                     /locus_tag="VUR04_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET5341081.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(8936..9754)
                     /locus_tag="VUR04_001182"
     CDS             complement(8936..9754)
                     /locus_tag="VUR04_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5341082.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFLQNGFNYSNYQGLGYANVMYPVL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(9741..10520)
                     /locus_tag="VUR04_001183"
     CDS             complement(9741..10520)
                     /locus_tag="VUR04_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5341083.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(10535..11026)
                     /locus_tag="VUR04_001184"
     CDS             complement(10535..11026)
                     /locus_tag="VUR04_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET5341084.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(11037..12227)
                     /locus_tag="VUR04_001185"
     CDS             complement(11037..12227)
                     /locus_tag="VUR04_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET5341085.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYESSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(12239..12667)
                     /locus_tag="VUR04_001186"
     CDS             complement(12239..12667)
                     /locus_tag="VUR04_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5341086.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            12938..13753
                     /locus_tag="VUR04_001187"
     CDS             12938..13753
                     /locus_tag="VUR04_001187"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET5341087.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATTVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            13772..14413
                     /locus_tag="VUR04_001188"
     CDS             13772..14413
                     /locus_tag="VUR04_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET5341088.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQYDEVAAYLKEVLAK"
     gene            14444..15445
                     /locus_tag="VUR04_001189"
     CDS             14444..15445
                     /locus_tag="VUR04_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET5341089.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSSTSIENLLANAQDIIR"
     gene            15455..16084
                     /locus_tag="VUR04_001190"
     CDS             15455..16084
                     /locus_tag="VUR04_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET5341090.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVDLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16463..16848)
                     /gene="tnpA"
                     /locus_tag="VUR04_001191"
                     /pseudo
     CDS             complement(16463..16848)
                     /gene="tnpA"
                     /locus_tag="VUR04_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17229..20429)
                     /locus_tag="VUR04_001192"
     CDS             complement(17229..20429)
                     /locus_tag="VUR04_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET5341091.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSENSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQAARTYLWEKFSNYKTSANLTVTYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     LHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQLQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            20652..21128
                     /locus_tag="VUR04_001193"
     CDS             20652..21128
                     /locus_tag="VUR04_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET5341092.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSDPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(21350..23565)
                     /locus_tag="VUR04_001194"
                     /pseudo
     CDS             complement(21350..23565)
                     /locus_tag="VUR04_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
     gene            complement(23966..24142)
                     /locus_tag="VUR04_001195"
     CDS             complement(23966..24142)
                     /locus_tag="VUR04_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341093.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(24521..25867)
                     /gene="celB"
                     /locus_tag="VUR04_001196"
     CDS             complement(24521..25867)
                     /gene="celB"
                     /locus_tag="VUR04_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET5341094.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFRSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(25947..26453)
                     /locus_tag="VUR04_001197"
     CDS             complement(25947..26453)
                     /locus_tag="VUR04_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341095.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKVYQQFVQ
                     LEKNSLSL"
     gene            complement(26484..26798)
                     /locus_tag="VUR04_001198"
     CDS             complement(26484..26798)
                     /locus_tag="VUR04_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET5341096.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(26808..28787)
                     /locus_tag="VUR04_001199"
     CDS             complement(26808..28787)
                     /locus_tag="VUR04_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET5341097.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSRFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVKGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(28905..29219)
                     /locus_tag="VUR04_001200"
     CDS             complement(28905..29219)
                     /locus_tag="VUR04_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET5341098.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(29349..29588)
                     /locus_tag="VUR04_001201"
     CDS             complement(29349..29588)
                     /locus_tag="VUR04_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET5341099.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(29640..31076)
                     /locus_tag="VUR04_001202"
     CDS             complement(29640..31076)
                     /locus_tag="VUR04_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET5341100.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSLAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIDFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDKVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(31266..>31468)
                     /locus_tag="VUR04_001203"
     CDS             complement(31266..>31468)
                     /locus_tag="VUR04_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET5341101.1"
                     /translation="IEKEGTILLIDQWINQEALDKHHQSKTMQKILDLRKKYHLQMQV
                     ERYIEDDSGMPESDKSFIDTGN"
BASE COUNT         9620 a         6764 c         5181 g         9903 t
ORIGIN      
        1 agtttgttct ttgattttca ttgtgtattt aaatacaaaa acaccctgaa acatcaggat
       61 gccattctta cattaaatac aaaattgcta gggtcaggag acttgctaga agtcccactc
      121 cccaaaagaa gaagtcaacc ttccactcgc tccaaggatt tcctttacca gacaatcccc
      181 caagctcaaa atggtgatgt acaggcgtca tacggaaaat acgtttacca cctgtcagtt
      241 tgaaataact gacttgcatc ataacagaag ttgtttcaaa aacatataca attccgataa
      301 tcaagagagt ccattcttgg tggagaacca tagagatagc tgccagcatc ccacctaggg
      361 ccaaacttcc cacatcaccc ataaagacct tggcaggctt atggttaaag atgaagaaac
      421 cgagcaaacc accaatcatg gcaagaatca ctagaagaat atccatctga ccttgcacat
      481 aggcaataac tccataggca gacaaactaa tcacaacgga aatactagct aaaccgtcaa
      541 caccgtctgt caagtttact gcgtttgaaa aaccgactag ccagaaaaga gcgaagaaaa
      601 tatagaaaaa tcccaaatga actggataac caaagacaga caggatatcg cccccacgct
      661 catagaaaag atagaagata attccaccta gaagctgaag agctaatttt tgcttaggat
      721 taagcccctc attgatttta cgaaagacct tgagaaagtc atctaaaaat ccgaccaagc
      781 catacaagac taatatgaac aaaatcattc ccacattatt gctgaattgg ctactaaata
      841 gggcgaaaaa gaaagcaacc aaaacagaag taatcaagaa aaccaaacct cccattgtag
      901 gagtcccagc ttttgcctga tgctgtttga catcttcatg catctgctgg cctgtaattt
      961 gcgcctttct ataaaattgg ataaaggccg gaattcctac taaagttagt aaaaatgtca
     1021 caattccagc actgatggaa ataaacatat tagtctccta aagttaatgt aattttttta
     1081 atgtccttga tagctgtgtt agcacgaaca tcttgcttct gcacagtaga gcccgaacct
     1141 tgaaattcaa gttctatatt gagccactta gcaagggtct cagcagtctc ctttgtccaa
     1201 ccatacatat ctggaacttc ctctgcttta tcagataaga taaggacttg ctgattcggg
     1261 gcaagattct tcccttcttc agcagaactg tttttaatct tcgttcctgt tcccacaacg
     1321 atgggttgta caagattgcg acgcaattct tctgctaaat caccaggtga aatatccttg
     1381 acactaggca taggataagg actttgttga cttacttgct ccaaagcctt agctgttgtt
     1441 tgaagattga gagagtcttt catagctgaa gcccgctcca agataggatt ggcaaattct
     1501 cccaactgaa tacctgaata atgttcaggt tgttggaccg tcacatacaa gataaaatca
     1561 ggattttcag ccggactcat cgatacagcc gagaaaatat agtcggttaa cccgactaga
     1621 taaccaccat ttttctcgtc agcaatctga gccgtaccag acttgagggc tacattttgc
     1681 ccaggaacag ttacagttgg cttgcctgtg ctgtggttat acatggttcc ataaaccgga
     1741 tccgtcccta ccaaaaccat gttagtccga gttagactag ctgcatcttt agaaacagga
     1801 tttcccacaa tttctttttg agatttccga gcagtttgat catttggatc ataaatggca
     1861 ctaataaatt taggctccag catgacaccg tcattagcaa tagctgtaaa ggcacgaatc
     1921 atttgcgtct gggtcactga aatcccttgt ccaaatgagc tttgcgcaat gttgacaata
     1981 ttatccgcag gaagctgacc agcatactca tccgtcaaac cgaaacgggt cggaactcca
     2041 aatttaaaac gattaagata atcaagccag gtagcatctc ccatcttttg ctcaaggaga
     2101 gtcatcccaa cgttacttga gtgtgcaaaa ccttgagaaa aagtcatcat tctgccacca
     2161 gtcaatcctt cattaacgtc ccaatctcga atcgtggcat ctgcaatttt taactcacta
     2221 ctattaaaga cttctcctcc tggaaaggta ttattatcaa tagcagcagc caacatcatc
     2281 actttcatag tggaacctgg ctcatagtta ctttggtaaa ggatatcacg ccaaacaaag
     2341 tcctctgtaa tgccttcttt tgtatctgca tcaaaggtcg gtcgttgcgt tgttgccaga
     2401 atttcccctg ttttagcact gaccaaagtc gctgtcatgt actttccttt taccttctct
     2461 tgaaaagcat ccatctgggt ttccataaag gactggaggg ggctggaaat ggttgtataa
     2521 acatccttac catccatcgt tcgttgggaa acttgttctg ttccgggtac aatattaccc
     2581 agacgatcct tttcataggt aataatgccg tctgtccctg caagaatact gttcaaggaa
     2641 ctctccattc cagaggttcc cagcaagctc ttgcttccat cttcattttc atggagctga
     2701 gctaggccga taaaactaga agcaaattgt ccgtttgggt aactacgatt gggactggtt
     2761 gtaaaatcaa tccccttgac ctctgcagct tccaattctt ttttgataga catcatattg
     2821 gcataggtaa tcccatttcc ctttgctcca aaggaaactt gcttgagatt aggttgcgag
     2881 agttgctctc ttacatagga ttcttccatg tccagatact tatgaaagac ctctgcaacc
     2941 ttgttaaatt gtgttttttc tacgtaaaga atcttacccg ttgctgactt atagttctca
     3001 tcaatgaccg catagacatt ataggaggtt gcatcctcag caatcgggac tccatttcgg
     3061 tcataaatag tcccacgttt ggcaggaact gtacgggtgg tttgatgaac cttcttagct
     3121 tccttcgcta aatctgttcc aaagcgagtg cctgtcccaa taatgaccgc aaaattgact
     3181 aaaaaaatgg caaaaacaaa gacagataat aaactcagac tttttccaac tctgcgtctg
     3241 ttttcagccg gcgatttccg atttttggtc gcataacgga ttactctttt tgtccacttc
     3301 atatcttact ccgctattct aatattttca ttgtttaatt gcaaatcgtg tgaattggca
     3361 atttctttca aacgttctgc acgtaatagt tcattgacct cttgcttggc atcgtccaat
     3421 tcggtcttct tttcctctat ctgcgcattg atttttgtca aatcattctg cacttgcaag
     3481 agcttggtct gcataaaaat aatactaatg gctacaataa gagtggttac agcaatggaa
     3541 aagtaaaaag ctttttccac acgcgaaaac cgtttaagtt gcatctgtag tatttgacct
     3601 gttttttcca ttttttctgc catctttttc cctcttactt gtgaattttt ctgaccacgc
     3661 gcaacttggc tgagtgcgag cggttattgg cttctaactc ttccgcactt ggcaagattg
     3721 gcttacggga caccaattcc atcttgggct tgagatcatc tgggatgaaa ggcaagcctt
     3781 ttggaacttc aactgttgaa gcttccttga acaattgctt ggtcaagcgg tcttctaagg
     3841 aatgaaaggt aatcactgaa attctaccat ccagagccaa catatccata gcctgctgga
     3901 tggactcatc tgccgctccc agttcatcat tgacttcaat tcgaatagcc tggaaaatct
     3961 gcttagcagg atgacccttc ttcttgagtt ccttggcagg tttgaccaac ttgataatct
     4021 ctgctaactc agtcgttgtc tcaatcggct tcacttcacg cgcttgctca atcttacgcg
     4081 caatctgttt agagaattta tcctcaccgt atttgaagaa aatacgaacc aaatcatgat
     4141 agtcataatg attaaccact tcataggctg tcagactagc atcctgattc atccgcatgt
     4201 ccagtggcgc atccttttta taagaaaaac cacgctcacg ctggtccaat tgaggactag
     4261 acactcccaa gtcataacaa attccatcaa tttcctgaac accagcttcg cgcaaacgtg
     4321 cctgtaaatg acggaagtta tccttgataa aggtcaccat tcccttctca atgtaaggtg
     4381 ccaagcgttt ttgtgcattg tcaatggcat tctgatcctg gtcaaaggca tagagatggc
     4441 ctttttcact taatttactt aataaatact cgctatggcc tgctccaccc aaagtcgcat
     4501 caacgtagat accgtcaggt tttacgtcaa gcatatcaat cgtttcgtgg agtaagaccg
     4561 ttacatgatg aaattctttt gtcatatctt atctatttta ccacaaatcc gaccagcttg
     4621 cacttgtcag acaaatagga caaggagact actatttctt caaaaaatat gtcaaaaata
     4681 cttgacactt tatgtttaaa agactataat aaagtcaaat atatacgaca taaatcagaa
     4741 aggagaccag atgaatcgtg tgaaagaatt tcgcaaggaa ttgggtattt cccagctcga
     4801 actcgccaag gatatcggtg tctcgagaca gactatcaat atgattgaaa acgacaagta
     4861 caatccaacc ttggaactct gtctcaatct cgcccgcagc ctccaaactg acctcaacag
     4921 tctcttttgg gaggaagatt tttaaaaaag gagcaaactc atgaaaaaag aaaagaaaca
     4981 gttacgttat cctggtctga aagcaggttc gatttatgga acagtgatat tttttataat
     5041 tccactcatt gataccctaa caagtgaaaa tccaaatttt atcagttctc ttctaaatac
     5101 aaaacatatt tttaaaacta tactgggagc tttctttttc ggagtgatga tacatattgt
     5161 cgactcactt cgtattgcaa gagctaaaaa agaccaggat taggaggtgc cttatgaaat
     5221 cactagctag actactgatc attcatgttt ttatcagtat tttccttttc ttcgccctta
     5281 tttcaggagc tgtttctcat acagttttac tactcctact cctctttctt cctgcgctca
     5341 ataaaggact tgagaaaata caatcaaaac ggatacctgt cctcaacgca gccctcttct
     5401 ttctcctcat atcctttcca caacttttaa ccaaccctgt ccaatggaaa ttttcaatat
     5461 tcctagtcgt aaccatcatt tcaagtttgg cctacttcta taacttttat caagtagtta
     5521 aagaagtaga tcaaaaacag ttgatttagg agcttgctcc cataatttct catttcatag
     5581 gcaaataatc ccacctagct tgttctaggt gggattattt tatttcttaa cagaaattgc
     5641 aagtcatttt ccttcatttt agaaagtcga ctctttccaa ttcacactac aatccaagac
     5701 ttgttgcctt tcttcttgat tgcggccttc aatctgatca atcaaaatct ttgtagcctg
     5761 ttgtccttcc tcaaaggagg gctgaaccag cgtcgaaaca cttggagaag aaaagcaagt
     5821 ccactccgta ttgtcaaaac caatcaaccc aacttgtggc aagttataat tcaactcttt
     5881 gataacggta aagactagag gtagggccca acagttaggg ataaatacca gagttttttc
     5941 atcgggatcg atttcttttt gtaaaaattc cttaatttgt tccaaattcg tatgcttatc
     6001 ttcaatggtt agactggcgt gacgcatatt agcatctgtt aaagcatcca caaaaccact
     6061 tgcccgctca atccgagtac tcaaacgact cgtatccgct gtaatcaaga gaaaatgttc
     6121 ataacctttt tcgatacagg actgggtcat gtcataaacg gcatcatagt tattggtttt
     6181 aacccagcta gtccggtgtt catagagctg actatcaaaa aagaccattt tcttcttttt
     6241 ctcatcgatg atacgagaat attttcggaa attagaggtc ggctgaataa taaagccgtc
     6301 tactcccaag agaagcatgc tttcaatata ccggtcctca ctctcttggc tgtaattact
     6361 atttcctatc attacctggt agccattctg gctggcgata tcctcaattc ccttaacaat
     6421 ttggtttgag aaactgttgg taatatcacc gatcaaaaca ccgattaatt ttgttcgttt
     6481 ggagtttaag ctacgcgcaa caatgctcgg tttgtaattt gtttcatgaa taactttttc
     6541 aatcttttca cgtgtctctt gggacatttt ttcatatttc ccatttaggt aaaatgacac
     6601 ggttgttttc gaggtctgag ccatttccgc aatgtctttt atggtcagtt tcttctccaa
     6661 tctaaaacac ctcctactaa tacttattat aacatattca ctattcaaaa tgcctatttc
     6721 tagcactgca agcgaatcat tctctcattt attttatcat atactagaca ttttccacgc
     6781 atttttgttc cgtcaacgag gcacaatttt tcacctacgc caatatcctc gcttaataac
     6841 agaatcagct tgtctgtttc atcatttttc acttcaaaag ccagagcatt ttccacttca
     6901 cgatcatctg tctggtagac agaatgacgg atgatttcaa aactctcatg cgcaatgatg
     6961 gtataatcca gcatctgatt ctcaaagaat tggcgcttgg tgagtttgct acttctttca
     7021 agctcattgt atttaggaga aatgatggta tcttccaaat caaaatcaac ttcactccat
     7081 agtctcaact gattgatttt cccatcttga taggtcacat ccttgtcaag gataaactga
     7141 gtcaacgcct catgctgacc ttgacacctg atgtcatcta ccaagagcca gacatcctct
     7201 accaacatga ggatttttct cttgtgaaga taaggcaaat caggttctgc tgaccaataa
     7261 gccccttcaa tataatgcac tccctccctt tctttatggt gacaaaacag ggagtgagga
     7321 tagtattcat attcccagga tcccgtgatt ctttccggag ctttcccatc tacaatgcag
     7381 gtcgaatgac tccaagcact ctttaagaga taacgttcat atatctcccg ataagaataa
     7441 cgcccagcat ctatgaaaat aggttggcct tgatactgta agcaaaaact attctcgtca
     7501 ctatggctat gggcacttcc tagcggacca tttttgaaaa atagataacg atgttcatcc
     7561 ttaatgcaga catgtccaga gtcttcaaag atcatggacc taggctgcca agctctcttt
     7621 tcaaattcct gcagtcgctt gaccttttct cgccccagga acaagaggct aagcaaatcg
     7681 actttaacat ccagaccgtt aagaaggtct tccttgttca aaaccacagc agacaggctc
     7741 aacatttctg tcgtttctgt agaatcgcta tcaccaaaag ccaaagtccg tccatctaag
     7801 cctgtcatca tttgaatata ggtcgccatc ttttccagca actcttggta actatcttgc
     7861 aagtctggaa gcaagagaca caaatccagc aaggctttat aaacctctac atgatagaga
     7921 atcgactgtt caaactggct tccatctcct aaaatctgtg tctcaatttg ctgtttcaac
     7981 tcctctgaag caaaatggta agcttcttct aggtccatct tatctgaaaa gaaatgatag
     8041 atagcaagca tcggaattgt ttgtaaaatc ccccagttac taagggtgta cttggcgcga
     8101 tagtagcttt tcataaagtc aatctgcttt tctagactga ccaaaatttt ctctagttct
     8161 ttctcctcta gcaagtcaaa tttcaagaga agcaagagta gtttcaacca agtaaaggaa
     8221 cgaatacccg tatccaaggt tctagtcatc aaggattgag gagaaaattc tctcacctgc
     8281 tcaatccaat caaatagaaa gaacttgcac ttttgaatat agtccttatc tccttctacc
     8341 agatacccta tcataaactg caagagatat tcttgtcgat tgagcatata agcccattct
     8401 ggatcatctt caaatacttg atcccatacc atcggctgga tttgatggat ttttgaacaa
     8461 ggctccatat cccaaggact atcaaacata aaacgattgt ccatcaagcg ttcaagggaa
     8521 ctcttgactt tctcatagtc ttttgaacaa tgggacaaga tataatcacg acattggttt
     8581 ccatcgactc tttcaaaaaa ttgtcttctt tcttctttca ttatctatta ccagaaaaag
     8641 aactacttaa aaagcagttc ttttgtcttt cccattacac tttccttttc tacatagatg
     8701 accacacctt ttgcaatctg caaggagacc aagtcatctt ggatagaaat gatttttcca
     8761 tgaattccag acaataacaa cacttcatca ccagatgtta aagaagctaa atactcttgt
     8821 cgttgctcca tctgtttgcg aagcaacttt tgctgacgaa tagaatgaaa gcttgacagt
     8881 aaaaggggac tcactgccaa gacaatcact attccataaa acaatgttgt atccattaag
     8941 ctataatctt aagccagctt ccgataattc cgatgataac tgttaaaata acgagtttat
     9001 atgttgtcca tttcttttct ttgatcaagt agtaaactaa aagtgtaaat agggctggta
     9061 gaagagctgg agcaacctta tcaagcattc cctgaatact tacgatactt tgtttagcgt
     9121 ctgctttaac ttcccctgca gcaaaggtaa tcggcaccat aatcttaaca gatgtcgctg
     9181 ccaaaccagc aattacggtt acaccgataa tattggcaat acgagaaatc gttgccatct
     9241 gttcgcttag tttatcaatc acagttgttc ctagtttgta tccatacaga ccagttgaca
     9301 atttaatcgc tgttaaaatc gtattcatcg caaggaagaa caagattgga ccgacaacca
     9361 agccttcttg agcaaacgaa gctgcgatgg ttgagaacaa tggagctaaa cagaattgag
     9421 agagagaatc cccaatacct gctaatggtc ccatcaaggc catcttgatg ctacgtgttt
     9481 cttttgttgg tcggccattt tccaacatta caaggtgcaa gctggtaata aaaggcagga
     9541 agtgtggatt ggtattatag aattcacagt tttcttccaa ggcttggtag aaaccttcct
     9601 gatcctctcc atagtgtttt ttcaaaacag gatacattac attggcatat cccaaccctt
     9661 gatagttact atagttaaat ccattttgta aaaagaatgc ccgcaaagac gttttaagat
     9721 aatcacgttt tgttaatttg ttagatccag tcatcgtgtg cttcctcctc taccacatga
     9781 tccgctgttt ttggcttgtt ataaaattca atcaaagcaa agatagtacc tacaattgca
     9841 ataccaattg ttgggatgtt tagataagct gcacaaacat atcccaacaa gacaaaggga
     9901 atcaactctt tcttagccat cactgacaag atcatcgcaa aaccgatagc tgggagcatt
     9961 ttaccagcaa ctgtcaaacc tgtaagcaat accggtggaa tgtagtctac gagtttcaac
    10021 aaggtatcca ttgaaagggc acccaagcaa cccaaggtaa atccaataaa ggcaaacaac
    10081 caaattgttg catttagagt gaacttaaat ttcttcaaat tatggttttt caagtgcttc
    10141 atcgctgttt caggcgcacc agcacgtaca gtgtaggcga aagtttgtaa gaattgaatc
    10201 gccacagcaa tcggagtaga gagggcaaga gccgcttctg gactgacttt accagcacta
    10261 gtgatagcca tcaaggtacc aaagatacca ggtccgattg ggtttggtgg aacagtacct
    10321 ccagcaccaa caccgaatcc catataagcc aattcaccaa tagctcccat tgcaagagca
    10381 gtaggcagat cacctagaat aattccgaca ccaaatgaca gaacaataca tctattggtg
    10441 taaattccta acagcattcc actaaaacag aaagctgtcc ataatccaat taaaatcgct
    10501 tgaaatacat taatcgacat aacgatctcc tcttttaaat atagtccata atgttgactt
    10561 gaacagctcc atcatttcct gttggagttg ttttcgtatt aaatgttact tgatgagttt
    10621 ggctcaattc cttgagggcc gccttgtcct cttcacccag gaagatggag cgtgtcactt
    10681 gctctttacc agtagcattg tgaatgttcc caatattgat ttctttgata gggacaccac
    10741 cttctaccaa ggttaaagca tccttcacat cctttacaac gataaagatc gtttgagcag
    10801 gattagcctt gtgaatgata tcaatcacct tttgcaaagg gaagaaacgc atggcaactg
    10861 agtctggcac aactgttttc atcagagttt gttgcatctt gtccgtgctt acttcgtcat
    10921 tggcaacaat gaccgtatta caacctaggt attttaccca aagttgtcct tgtccatgaa
    10981 tcaaccgttc atcgatacgg gtcataataa tatttggcat tgtcatattt ctcctcctac
    11041 caatataggt tccagtcttt gtagaaacgg ataagggctt ctaggtaata gtagtcaccc
    11101 cagatattgc cttcatccac tcctttacct gaatgccatg agtacacacc gtggaggaga
    11161 cttgtcccac caggggtaaa ttgatcattt gcataatgtt cgatcaagga acgaagcatg
    11221 gcatgcatag catgtttata aatatctttg tcagcatcca cctctggaag atgttttagc
    11281 atttcatgaa tcccacagac ggcgatagct gttgctgaag aatctcgtga ttgatcacta
    11341 ccatcattaa aaatcaaatc ccaataggac acatgatctt ttggcagacg attcaagaaa
    11401 taattggtca cacccttaaa caagtcaaag caggactcgt cttttaagtg acgataagtc
    11461 aaaggaatac catagactcc ccatgattga ccacgtgccc agcatgaatc atcactatac
    11521 ccttgtctcg ttacaccttt aaagggttga cctgtctcag gatcaaaata gaaggtgtgg
    11581 aaggacgaag cgtcatcacg gattacatta ttagctgaag catagaaatg actttctgca
    11641 atatcgtagt atttttgatc gcctgtttct tgataagcaa agaataagag ttggatattg
    11701 agcaagcagt cgataatcaa acggtaatgc tctttcttgc ccaagtctcc ccaagcttga
    11761 ataaaaccac ctttttcttg atagcgttca atcaacttat ctgcagcttt caaggctgct
    11821 tctctagcct ctccatctcc atttatctta tattcagcca tacaagacgg tgtgtacaag
    11881 aagccgagat catggtgagc caattctact ctcttattga cacgatccag gaaagaaaga
    11941 acatttttat gagcgatgtt tttaaatgca tcctgttgac tggattcata agccaaccac
    12001 agttctcctg tccagaaacc attggtccat tccgtgttat ccatgattgg atagacatta
    12061 tcaaaggtag ctggcgtcgg gaaatcttcc ttgaaatagt caaggttgag ttctaactgc
    12121 cgaataacct tatcgattgc ctggccgact tcttctttcg tcagaagtgg tacttctaag
    12181 aagcgctcag gcgattttat tttttcaatc gtaacctttt ttatcattct tttacccttt
    12241 aaatacccga ttcgaaatct tcttcctctg catccgttga aaacaattct ttaccattta
    12301 cgactccgcc ctgggccgcc actactgatt tattaacaac ctcatcaaag ctatgagcca
    12361 ttctagcaaa gactgcttcc attaacatgg ctaagttcaa acccgagaga acattcattg
    12421 ttttgactgg attttctccc attatggtag aagaaacctt gaatggcgat cctcccaaga
    12481 gatcacttag gattaaaact tcttcttcat ttgaaattgc aagtaagatt ttttgcttga
    12541 gttcatctgc tgacattcct tccacaaagt caattgcctc cacattttct tgattgcctg
    12601 caatcaattg taaagaacta taaatccctg tagcaaaatg tccatgccct acaagtacaa
    12661 ttttcatctt ttctcctttc ttgtttaggt ttaccggttt actttatatt ccccattgta
    12721 atcctttatt tttatcttgt caatagtttt tttaaaaaaa tattagcgct ttcattatct
    12781 ttttaatcat tttaatagac agaaatttca aaatattcca tttttaagga aaataaatct
    12841 ttttataaat aaaaatattt atttattgac aaaaccggtt tactagaata taatttggtt
    12901 atagagaagt cttaacaaat ttgaaaggaa gtatcaaatg acaaatacat cattctcaat
    12961 tgagcagttt tctttaaaag gaaaaattgc tctcatcacc ggcgcttctt atggaattgg
    13021 atttgctatt gccaaatcct acgctgaagc cggcgctact actgtcttta acgatatcaa
    13081 tcaagatctg gtcaataaag ggattgaagc ttatcgtgaa gttggcatcg aagcccatgg
    13141 atatgtctgt gacgtgacag acgaggacgg tatccaagcc atggtcaagc aaatcgaaca
    13201 agaggttggt gtcattgaca tcctcgttaa taacgctggt attatccgcc gagttccaat
    13261 gtgcgaaatg agcgccgctg atttccgtaa ggtcatcgat attgacttaa acgcaccatt
    13321 tatcgtttca aaggcagtta ttccttctat gataaagaaa gggcatggaa agattatcaa
    13381 tatttgttcg atgatgagcg aactgggacg tgaaacagtt agcgcttatg ctgctgctaa
    13441 agggggcttg aaaatgttga cccgcaacat tgcgtctgaa tacggtggag ccaatatcca
    13501 atgtaacgga attggaccgg gttatattgc cactcctcaa acagcacctc ttcgtgagtt
    13561 gcaagaagat ggttctcgcc acccatttga ccagttcatc attgcaaaaa cacctgctgc
    13621 acgttgggga aatcctgaag atttgatggg ccctgctgtc tttctcgcta gtgatgccag
    13681 caattttgtc aatggccaca tcctatatgt agatggcggt atcttagcct acatcggaaa
    13741 acaacctgag taaaaataga aagaagatct tatgaaaatc gcattaatca atgaaaatag
    13801 tcaagctagc aagaatcaca ttatttacga tagtctaaaa gaagcgacag ataaaaaagg
    13861 ctaccaatta tttaactatg gtatgcgtgg agaagaagga gaaagtcaat taacttatgt
    13921 gcagaacgga ctaatggctg ccatcctttt aaatacaaag gcagttgact ttgttgttac
    13981 cggctgtggt acgggtgtag gggctatgct tgctttaaac agcttccctg gtgttgtctg
    14041 tggtctagca gtggacccaa ctgacgctta cctttattct caaatcaatg gtggtaacgc
    14101 cttgtctatc ccttatgcca aaggatttgg ctggggggca gaactgaccc tcaaattgat
    14161 gtttgaacgc ttatttgctg aagaaatggg cggtggctac ccaagagaac gtgtaatccc
    14221 tgaacaacgc aacgctcgta tcttaaacga ggtgaaacaa atcacccaca atgatttgat
    14281 gaccatcctt aaaacaatcg accaagactt cctcaaagac accatctctg gcaaatattt
    14341 ccaagaatac ttctttgaaa actgccaata tgatgaagtc gctgcttatt tgaaagaagt
    14401 attagccaag taaagctatt ctaaaccaga aaggaactaa tggatgacga aaatattact
    14461 gtttggcgaa ccattaattc gaatttcacc attagatgcc accagtatcg gcgatcatgt
    14521 tgccagttcg acttattttg gcggatcaga aattaacatc gcttgtaatt tgcaagccct
    14581 gggtatctca acgaaagtct ttaccgcact ccctgccaac gagattggag atcgttttct
    14641 cacattcttg aaacagcacc aaatcgatac cagttcaatc tgtcggcttg gcgatcgaat
    14701 cggcctctac tatttggaga acggctttgg ttgtcgtcaa agtgaagttt tctacgatcg
    14761 taagcatacg agtatcagcc agattcggcc aaacatgcta gatatggatt ctctctttca
    14821 ggggattagc cattttcatt ttagtggaat caccgtagct atcggtcaag aggtccgtgc
    14881 gatccttctc ctactcttgg aagaagccaa gcgccgagga attgtcgttt caatggatct
    14941 caatctgaga acaaagatga tttcagtcct agaagccaag tatgaatttt ctaagtttgc
    15001 acgttttact gactattgct tcggtattga tcctctcatg attgatgacc aaaatctaga
    15061 gatgtttcca agagacagtg ctagcctaga agaggtggaa aatcgcatgc gacttttaaa
    15121 agaagcctat ggtttcaagg ccattttcca taccctccgc tctagtgatg agcaagacaa
    15181 aaatgtctat caagcctatg ctctagaaga actatttgaa gagtctgtcc aactaaaaac
    15241 tgcagtctat caacgaattg gtagcgggga tgcctttata tctggtgccc tttaccaact
    15301 actccatcat tcctccctaa aaactaccat tgactttgca gttgcgagcg caactctcaa
    15361 atgcactctt ccaggagacc atctctccac ttcctcaact agtattgaaa atttactggc
    15421 aaatgcacaa gatatcattc gttaggagaa ttacatgacc aaatcagata cgattattga
    15481 actaaaaaaa caaaaaattg tcgctgttat tcgaggaaat acaaaggaag aaggactgca
    15541 agcctcgatt gcttgtatca agggcggtat caaagctatt gaaatcgcct ataccaatca
    15601 gtatgcaggg caaatcatca aggaacttgt agacttgtat caggacgatc agagtgtttg
    15661 tatcggtgca ggtactgtgc ttgatgccgt aactgctaga gatgccattc tagccggagc
    15721 aaattacgtt gtttctccat ctttccatgc tgaaactgca aaaatgtgca atctctacag
    15781 cacaccgtac attccaggct gtattaccct cacagagatc acgactgcac ttgaagccgg
    15841 tagtgaaatc ataaaactct tcccaggtag tactctcagt ccagcatata tctctgcagt
    15901 caaggcaccg attccacaag tttccgtaat ggtaaccgga ggagtcgacc taaacaacat
    15961 ccctcaatgg ttcgctgctg gtgcagatgc cgttggaatt ggtggcgaac tcaataaact
    16021 cgcttcccaa ggcaactttg accgcatcag cgagattgcc caacagtatg ttacactcag
    16081 ataaaatcat aaccacccgt caaacgggtg gtttatccca gagctataag ctcaaattac
    16141 cagccagcgc ctaaagacgc tggcttttac gttgttcaag ccttattgct cttgactcgt
    16201 cacttgcctc tttaagagac tttggtatta cttaccacta tccctaaagg gatcctcata
    16261 ttcttttaca ctcaatttat ctagtgctat agtagattga aactggaata gtacacctct
    16321 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgattttgt cctgttctta
    16381 tttcatttta ctatatatca tgctttactc gttctcaaat tttcatactc gtgaagaaat
    16441 catccactgg ataatttctt taatcttgac tatatttctt aattgtggct ttattaagcc
    16501 ctactgtact tacaaaataa ccttccgccc agaaatgccg attcccaaac ttgtacttga
    16561 gattggcgtg tttgtcaaac atcatgagtg cacttttgcc ttttaaatac cccataaaac
    16621 ttgaaacact tagccttagt ggaatactga ctaacatgtg tacatggtct ggcattaagt
    16681 gaccctcgat catttcaaca cctttataac tacacaagcg atgaaatatt tcgcccaaac
    16741 tacttctata ttgattatag atgacttttc gtctatactt aggggtgaac acaatatgat
    16801 agaacacatc cactttgtgt atgataaact atgagtcttt tgtgccatat tttttctccc
    16861 ttcgctttac aagtggagtg aacaccttta ttgtatcgtg tttggagttt ttttggtata
    16921 accttcgacg cgcacccgca tagcgggtgg ttgttttgtc tcgcacctca cggagcgaga
    16981 cggactaata tagtggagtg aaataggata cgaacaaatt gattaggaaa atcaaatgaa
    17041 tttatagaaa tcttttagca gttatgacgt cctattctag tttcaaaacg ctatagtcac
    17101 ataatgaagt aaaaaaggat aagtatcaac ttatcctttt ttaaaagaaa aatccgaaga
    17161 tatttggcct tcttcggatt ttttctattt tccacagttt catgtaattc atctagatga
    17221 tgaacaaatt agttgttctt tcctctacgg aatagataaa acgccccaag tagcaagaac
    17281 cctagacttg ccaagattga ctgaccttct cctgtctgag ggagattctt ttgatccgaa
    17341 tggttctttt cctcttcaga tttttccttt tcttttgaat tctgtacttg tagctgagct
    17401 gcttgctcta gctttttaaa gacttcctga tctggagctg attcctgggt ttcaggatta
    17461 tagtaggcaa tcttatattc atccccttct tttcgaatgg tatagactcc acgtttcaaa
    17521 acttggaatt ggttggaaat agtagagaca gaatcatcat atttcacaat gccccaaact
    17581 ccttgtttgg catcataaac agactgaagg gtttcgttat tttcgatgag gctactttct
    17641 aactctttta tcatttgatt gaaggtggca cgatccacgt taggaatgag catatagcca
    17701 taagaatctc cattttgctt atgagcctga ctaatcgtaa gaaattcatt ttcaacttcc
    17761 ttgtctgact gtccttcatt gatatccttc caggctccct tttgcaaagc cttactcata
    17821 ctgattgaac tcttcttaaa gaaaaagtaa ccaatattct ttttcgaatc agacgattct
    17881 aaaaagacac tttgggtttc aggataatcc ttttcttgtt ctgtaaggga ggcttcttta
    17941 tcattgacat agactttata tggattactt gattccagtt ttctctggtc aattgtagtt
    18001 gcagcagtat ctgttgaagt gttttggata ttgcttccta aaaaggcgat cttatccttc
    18061 agcataaacc agctcttatg agcagtcaat gtttgattcc agttggtgaa atccatggtt
    18121 gctgtcgcat tggcatcatc tagtttgctc gttccaacga aagcagacgg taaaacttta
    18181 cctgtatcgc tatccgctct cttagcatcc gtctctgttg taccaggcat cttatatgga
    18241 ttaactgttg gccagtagcc atcgctatag tgactcaaat cgccattgta aagatagaac
    18301 atcccatcac tcgtatacca accacgttta ttttccttgt tcatgtgttc gtaattcaag
    18361 gtacgactgg aaaagagtga caagccaaat ccaaaccctt tctctgcatt gtacatggct
    18421 gttttatcca tcttgttaaa ggcagatagg taacttggtc ttggaacact tgcgactcct
    18481 gcatcactta acaaggattg catcaaactg atatccttat aagtcttcaa attcttaaag
    18541 acatcataat aactatccga ttgaacaatg gtcttcacaa gactctgcaa acgttgtttg
    18601 gtttctcctt cagacatatc cgctattcgg tgaatccctc ttagtacttc tactgcggcc
    18661 acgtgcccct cgctatttgc acgactgatc gagcgtccac gactcatatc catcagctct
    18721 ccattcacca gcaaaggagc aaacgattta tcaatccagt ggtacatggt ttgcatttta
    18781 tctttatcga ttggactctt ggtcttttga atgactggca acagttgaga cagaccatca
    18841 atcaaaacat tcccataagc acccgtatag gcaacattgg tgtggtcgat ataggatcca
    18901 tcttgataaa aaccttcacc ttggtctacc aacttgaaca cttgctcaat cgagcgaatg
    18961 gtagaagaaa tttcttgatc atccttacgc agtaaaccag ctattacttt tacccttccc
    19021 atatcaacta agtttccacc tagagccttg aatgggttat cagtcgtctt tcggaaatgt
    19081 tcgggatctg gtacaaattt ttcaatcaca tctgtatatt ttttaatttc ctcatcagag
    19141 aagtattctt tcatcagaga caaggtattg ttgatggcac gaggtgtacc gatttcataa
    19201 tcccaccagt tcccaacaat gctcttttca ctattgtaga catgtttatg cagccattcc
    19261 atggaatccc tgactgttcg aacgacagtt tcatcttgat aataacgaga agaaggattg
    19321 gtcacttgct tggccatctc ctccaatttc cgataagtga cagttagatt tgcagacgtt
    19381 ttataatttg aaaatttttc ccacaaatag gtgcgggccg cctgacttga aatactggat
    19441 aggctatcag ctacctttcc ttccaattcc tggtttaatt tggccatctg ttcattttta
    19501 gaatcatagt attgattccc agcgatgatg ccattccagt catccaaacg gtctgtgtat
    19561 gtatccttaa cagaggctag aatcttcaaa ggaatctttt tcacttcctt gccatcttta
    19621 ctgacaatga cattggttgt cccttcctta agaggttcta aaattccatt tttgactgaa
    19681 gcaacgtcag gattttctac cttataagta tagtccgcaa gagaaaaaac atgttttttt
    19741 ccaattggta aatcaatctt ttcctcaagc tgtttatctg tttgagaatt ctcagaaggc
    19801 tggtctgcta cctctaccag ctcaatatcc ttaaaggaaa cagtcccagt tcctgtttca
    19861 tagaataact ccagcttgat tttatcaaca tctaaagtcg ggctatagtc tgcttcaatg
    19921 gtctgccagt cctttgttcc tgacgtcgtt gcagaattcc acaatcgctt gtccttacca
    19981 ctttcctcaa tgatacgaac tttggcaatc ccgattttat tatctgtttt aatcttgaaa
    20041 cgcagtttat actttttctt agcttcaata ggaaccatac ggtgaagcgc tgcccttaat
    20101 ttctcatggc ttgagatagt gatagcccca tccttagcct caatgactcg agttgaggca
    20161 tctgcactat tcttctggtc tacccaagct gaccacccct gagctttgct tcctgtccac
    20221 ggactgcttc cgtcctccgt ctgaccaaaa tcaccatttt caactaaatt ttttgtatcc
    20281 ctttgctgat actgaacttc cttctggctt tgctgaatgg tattcgtagt cgtttcttcc
    20341 gctccaattg tcatataatg gtttaataaa aatcctgata aaacaagtga agacaaactc
    20401 acaatgagct tctttgtttt tgtttgcatg tatacactcc aataaacata ttgtaaaatc
    20461 aataggaact aaatctcaaa ttagagattt atagcaacta agtaaaccga tttaattaaa
    20521 tcataccatt tttaaagtta tttgtaaacg gtttctatca tattgaaggc ttattcttca
    20581 acaatatctt ccatccgact cgacgaaaaa agtaaaaact gttacaatgt agaaaaagaa
    20641 aagaggccct catgacttca ctttatgatt tttccgtttt gaaccaaaac aaccaagcaa
    20701 ctcccttgga tagctatcgt ggcaaagttc tcttgattgt caacactgct actggatgtg
    20761 gtttaacgcc ccagtaccag ggacttcaag aactctatga acgctatcaa gatcagggct
    20821 tcgaaatatt ggatttccct tgcaatcagt ttatgggaca agcacccggc agcgcagagg
    20881 aaatcaacgc cttctgtagc ctacattttc aaaccacctt cccacgtttt gccaagatta
    20941 aggtcaacgg taaggaagca gaccctctct atgtctggtt aaaagaccag aaatccgacc
    21001 cactaggaaa acgaatcgaa tggaatttcg ctaagtttct catcggtcga gatgggcaag
    21061 tctttgaacg cttttcttca aaaacagacc caaaacaaat tgaagaggcg atacaaactc
    21121 tactataatt cacaatctca ctatgattag gtttccttta acctgatgaa tagtgagatt
    21181 ttttgattgg ctttgactta aatagaaaaa caccccatga tatgaaacat gaagtgttgt
    21241 aaagtctatg ttgtaggtgc ttatttcaca ttttcaatgt gaccagtgat aacgaatacc
    21301 atacagaatc ttcatataca ctaaacaaat gactttctaa ttatttcaat tagttttggc
    21361 tagtaaatat catttccaac aaacgccctc tcaattcctt atcctgatga tgcaagatat
    21421 tcattaagtc atgagaattt ttggcattga tgaattgatt taacaatcta tcttttaatt
    21481 catatggaag agaagctgtc tttagtagtc taaaaacttc gtcatttaaa gatgtccttt
    21541 tattatcttt ccattcaaat ttagctgtat tattcttatt tggcaattca attatagaca
    21601 cattcgttcc tttaaaatga attctatgtt ttctattgct tggaacgata ctagaatctc
    21661 cttgtaatgc taactctacc attcccattt cccaatcgat tgataatctt gttttatatc
    21721 tttgaccatt ttgatcttcg atcatttcaa aagaatgttg ttttcctggg aatacatacc
    21781 aatctacaac ttcaggtaaa tcaacaccca tacctatctc agaaccaacc aagggaatga
    21841 ttgcaccact ttttgcaaac acaggcgtag tcgagatgtc tctataaaca cttaacttca
    21901 caccacctgt gtattttttc tctgaaaaga agtcatacca ttcaccttca gggaaccata
    21961 catctacttt tgcagattgg aatgtcaaat ccatcttttc tacaatggga gccaccatca
    22021 gttctgttcc aaaaaagtat tggtttggaa cattatagct ctcatcattc tctggataga
    22081 aataatagat tggactgatt aatggggcac cttcctcatg tgtctttaca ttcatggtat
    22141 atagataggg aatcatctga tgtctcaaac gaaggtattt cttcataatc ttagatgttg
    22201 tttctgaaaa gaaccaaggt tctttactat taaaaggact tctagaacta tgtaatcgag
    22261 taatcggact aaaaaaacac caaactgtag ccatctagtt tgtagctctt cgtcataatc
    22321 ccccaacata tgtccaccga tatcatgact ccaccaacta taaccgatat tagatgctgt
    22381 cgctgtaaaa tagggttgaa atcttaagga attccaacta ataatagtat cccctgaaaa
    22441 accaacaggg tagcggtgac taccaggacc tgcatatctt gataaaatca aaccaccttc
    22501 tgcattttta caactatcct gatagtgata atggtttaaa agccaaagtg gatctagcat
    22561 accttgtgtc ccttgttgcc agtcaatcca ccaaaaatct actccctgct tttctagctc
    22621 ataatgaaca tctttaaagt aggcttccct aaaagaggga ttaaaaaaat caaaaatagc
    22681 aggttcttct agttctacat ttaaccccaa tcgttttgcg atttgaggat aagcttcttc
    22741 ataagcccgt atcccatcag caggatggac atttaaggag agttttaact ttctatcatg
    22801 aagttgttgc aataactgtt ctggatttgg tattaagttt ttattccaac tatatcctgt
    22861 ccagccactt ccaaaacgag ctggaatgtc agttatatgc caatccatat ctaacacacc
    22921 gatagataat ggaattttct ctgtttcaaa tctgtctatt aaatccaagt attcatccga
    22981 cgtataaggc caatatctac tccaccaatt gcctaaagca tatcttggca acaagggtgt
    23041 tgaaccagtc aaatggtaaa aatctctgat tgctcctcta taatcatgcc cataggcaaa
    23101 aaaatacagg tcaatttgat tttctctctc aatataacca gattgttcat cccaaataaa
    23161 tccttgagaa tcatccaata aggctatacc atttcggcta ataattccat cttctaacga
    23221 gattgctcca tctgccttat ccagagtccg agctgttcct tttaacgttt caatagattc
    23281 accaaaatac cagcgactac catatacggc aaaatttcct tttaattcta taaataaatt
    23341 ttcggcgtta aattctcctt tattaaagtg cagatgaaaa tagtccgtca taatatctag
    23401 tacgtttgat gtctcgatat aatctaacga aacttggcca aaatctctat tatagataag
    23461 ttgtgtcgtt ctatcctcaa aacttccagt ttgagagtat tctaacctta ctagcttgtc
    23521 tgttaataca gagattcgat aaaactctcc cttaaaaatt ttcaatttgt tttcctcctt
    23581 ttatggtagc ataaaaacag aacgcaccat ttttgatgcg tttttcatta ttctgaatgc
    23641 aatgttctat ctgttatatc tatgacaaat aatagtcaat tgaaaaaatg tagtggacaa
    23701 aatatctttt aacaaaccaa gagtttatta aagagttatc acctttcaac ttttctaagc
    23761 ttatgcagtt gtgaaacaaa ctacttttaa actattaact aagataggat tgataaataa
    23821 tttcaaactc ttactagcaa tcatacgata ttcaagctcg cgtgcttttt tccttcctgc
    23881 ttatttctta gaactgaaga acccggatcg gtatataaat tatccggatc aacatagtca
    23941 taagattcat aacagttgcg cttcattaag tcatccccag agcaagagct tcatctcgta
    24001 atttttcaac atcactaacc gtaggtcgcc atccttcaat catatttgta cttaaagcat
    24061 accaaacact cttaaaaacg gatcggtttt caaaagctat tcccatgatt gtcatctttt
    24121 ctttatctat atctaaggac atatgctacc tcctttagat acattatacc atgtttctat
    24181 gtagctttta aaaattttat tttgtttgtc atatctaagt tttcagcacg cttatcctat
    24241 tttataagcc tcaaacccaa atataaaacg cattcttttt gcttttttac tattgtatcg
    24301 tattctacga taacatactt tactttattg tttttttaaa taacagcagt tccctgttta
    24361 tcaactattc gaactacttt ctattttgct tcatacccta catagcgaaa aaatatgaaa
    24421 aagcagagaa gaatatctta aaaagacctc ttcactgcta atgttaacgc tcattattta
    24481 aactatatgg attctatcat cgagtatact tttttactta ttagatacct tgctcttctt
    24541 tcaccaattt ttgatcatat acacggatga atggaagata gactaggaat gctgcaaatg
    24601 cacatactag agcaactaat acagctcgaa gatctgctgt ccctaagaaa gctccaatcc
    24661 ctactggagt tggccatgga acctgtgcga taattggctt aataaagttt agagaattcg
    24721 ctacgtaata aatagtagca gtaaccattg gtgctaaaat aaatggtata gccaaggctg
    24781 gattatagat aataggtaat ccaaaaatta atggttcatt aatattaaat aaggctggaa
    24841 ctacagatgc tcgtcctatt gctttaagct gttcagattt agaggcaaaa gcaatatata
    24901 aacatagtcc taaagttgca ccagaaccac ctgcaattac aaacatatta gaaaattcac
    24961 ctgcaacagc gaagtgcccg ccagcagcat tttcagccat gttggcaaga gcaattggac
    25021 taacaaatgc aaaaacaatg ttcgcaccgt ggatacctac aatccaaagt agttgagtca
    25081 atagataaat aatcattaaa ccaatccacg aattagtcag attggataca aaaccaaatg
    25141 gaattgcaat gactttaaaa atatctgttc ccattgctac aagaagaccg ttgataaaga
    25201 taacaacaaa tgcaacaaca aatcccggaa ccaaagcggt aaatccacga gaaactcctt
    25261 ctggaacagc ttcaggcatt ttaataaccc aattatgttt aacacacata cgataaataa
    25321 gaacagtcac aattgccata atgattgcgg taaaaatccc tgttgtccca aaacgtgcga
    25381 ctccatttcc cattgcccat ccatctgcaa ttactgcacc ttcttttaga cttgtcacag
    25441 tcttcatcat tccaccatca aaaatgattt gcggtactgt catgacaaaa gccatcaagg
    25501 caagcaaggc accattaaga ggattcatat tgagttcttc ttcctctgca taaatttttg
    25561 tcaattcata tgcaagtgat agaacgaaat aaagagatag agaacccata gtcgcatagt
    25621 ttgcaaccat gtaaagtgat ctgaatttat caaatgaagc agagaaaata tctgccacaa
    25681 ttggccaaaa tgagaaagct tgtggcaaaa tactgaatac caaaaacatt gatcctacaa
    25741 tagtaaatgg tacagcagcc atacctgcag ccgtgatagc acgtactact ttaaactgag
    25801 caagtttgcc cattggtccc ataacatggt tttcaagaaa accaaacaac ccgttttgtt
    25861 gatccataaa tagacctcct taataaaaca taataatttt tactttctaa agactagttt
    25921 caaatacaaa ttatactaga tcaggattat aaactaagtg agttcttttc caattggaca
    25981 aattgttgat aaaccttatc tgttcgttta taaatttttt taattcttct aatgtctaac
    26041 aaactcagaa ctaaacctaa tagaagaact acaaaaacaa ataaacgtgc tacttggtta
    26101 ttttcaaaaa tcggaaaaag attcttaaac caacttgtcc aagttaaaac aagtaatcct
    26161 attgaaataa gcatttgtat tctaacaaac attagtgtta ttcccaactt ttctttccta
    26221 tttccataga gtttaaattg ttcaacagtt gctaaaatag aaaatactat gagcataatg
    26281 gggaaaataa taataggcga gggattaata aactgattca aaagccaata aatattccca
    26341 aaaaagaaga gtgctattga ataacgtaga agaagatatc gattaaaaaa agtattagtt
    26401 agagccatct ctcgacgttg ttgttcaatc ttttgtcgtt cttttttatc catatcattt
    26461 cctccttata taacaacaca tatttagtta actttcttat aaagagctaa catttccttt
    26521 gctacttcta ataatgtcat agtggtcatt aaatgatctt gagcatgtac catgataatt
    26581 tcaattttaa tttccactcc acttgcgtat tcttgcaaga gtttggtttg tgcatgatgc
    26641 gcttcaagaa ttatctcatt tgattgattt aatttacttt ctgcatcatc aaaactacct
    26701 tctctcattt ttgcaaatgc ttcatgtatt tctgaccttg catttcccga atgcaggata
    26761 atttcaaatg ctgcaacctg cagttcctct tgattcatat gaacctccta ttttatcttc
    26821 tcaaatatgt taataaaatc ttcaaagtta ttgcaagata ttagctgatt ttgcaactca
    26881 tcattctctg tcagagagac tatcttttta gtcacagttg ccaaaccttc gttcccatat
    26941 attgatggag atagaagaaa tactagctgg acatatgaac tttgattatc ccagagtaac
    27001 gaatctttac agattgcaac cgaaaccttt ccctctgtac caaagggctg aataggatgc
    27061 ggaactgcaa ttttttcaga aaaaacaact gaacttaatt cttcgcgctg tttaattcca
    27121 taaagtaaag attgttcgaa ctcatttgat tcaccaacag ataaaccctt aaccatcttt
    27181 tcaagtaaat ttaccttgtc tgattcagta catattaaaa aattttcttt actaaaatac
    27241 tgtctaaagc cgttgttttc aaatttgtta atctttgatg attgtacata actagaaact
    27301 tgcatctgat ccatagcttt tctaatcatt tccatctcat cactcttaag aaacacacta
    27361 actttaaaaa ctgggatttg aaaatataga tttgataaat caacagctga cactataaaa
    27421 tctattcctt taagtttttc ttgattcaat tcataatagc ctattacatc aacaacttct
    27481 actcgcttcc caaactccgt ttccaaacga tttcttaaca tttgggctgc accaaatcct
    27541 gttgcacaaa tagcaagaat attaaactta gtactctctt tgctacgttc catagcagct
    27601 aaaaagtgaa gacttacata tgctacttca tcatctgata ttgtccactc caagaacttg
    27661 tccatatttg caagaatttc tctagtcata aagaatatat cactataatt ctgtttaatt
    27721 tcatctacca aagggttatt taaggtaatc cggctttcta aacgtacttg tagtgtcatt
    27781 agatgagtta tcaatccttc aattagttgg aaatctgaag aaaagttata catatcatct
    27841 aatcctaaat tctgaaatgt tttaaataaa gattttttta aaacttcttc agaaatattc
    27901 ttctgatttt tttgacattg ttgactctta gctaacaaat gcaaagtaat gtagtctatt
    27961 tcctgaactg gaaattcctg atttgttact tctcttactt tagaaagaat tctttgggca
    28021 acctttctct ctattgcatc atcagtcatc tgacagtcta tattttttat ttcaaatctg
    28081 gattttaaac gaatcacaga caatgctatg tgaactacta aattctgtag tacaaaatca
    28141 gatagtttta ggttggcctc ttggcattca tccaaaacaa ttctagcaaa ttcttctaat
    28201 ggaacagttt gatcaaaaaa gttaaatttt acatagcaat gtattgtttt aaaaaattga
    28261 ttctctagga aataatttat gataaaacgt cgtttatcac gttcctcgcc tgagacataa
    28321 actcctttat tcgccctact ctcaatggac aaattatact ctgataacat cactcgtatc
    28381 tttctgaaat catgagataa tgttgaacga ctaacgtaaa gttcatcagc taaatcatca
    28441 aaaagaactg gaacttgctc aaataataat ttatttaaga taaatactaa acgatcatca
    28501 ccttttgaaa ccgcagtttt cgtatagtct tcttccagtt cataagtttg tctaaactcc
    28561 tggtaagcgc cttgattctc aaaaaatatt tgataccctt gaccttgttt tgaaatcaac
    28621 cggactcctt gaataatcat tgtcttctca attaatttca gtacattacg gacagttcta
    28681 tctgaacagg ataaatattc tgccagttct ttgcttgtaa caaaacgttc cttatttttt
    28741 attaaaaatt gaaggatatc tttctcttta atgtttaaca cattcattcc ctcctaaaac
    28801 gtatgttttc atatattgaa gcatattata cacttaaatc aatttatatc aaactcaaaa
    28861 caatttatct taacttaaat atttattgac atttcatgtg ttcatcaaat attctcaaga
    28921 atcaaattag ccattttttc aattcccatt ggaataggaa tataggcttg aggaggtatt
    28981 tgtacaactg gttttcctgc tttagaacca gcctcttcaa attgcttaaa gtacattttt
    29041 gtttgaggac tgacaagata caaatcaaaa gctgctgctg cgatagcttt ccctccttca
    29101 gtagcactaa tagcatcaac tacaatatct ttcccttttc cttttagaaa ctctgttgtt
    29161 ttctgtgcca taagtgatga agacattcct gctgcacaaa taattaaagc ttttgccata
    29221 atattttctc cttttcttaa atccaatcaa agctgtgcta agttggctta tttgttatct
    29281 atttttatta taaaataaag cgtttccaat gacaattccc tcattttcct aaatgatatg
    29341 gaaaaaaatt atttatactt caatttataa aataaaatta ttcctgagag tagaaatgaa
    29401 acactatttg ctaaaatcaa aggcaagtct cctatacgaa taccatgagc aagccacaat
    29461 gcaataccaa taacttgcat aacatacata cctagagcaa tagatcctgt gtcctttgtc
    29521 ttaactacac gaaaaacttg tggtaaaaat gcaaatgttg ttaaaattgc tgcaatactt
    29581 ccaatcatat gtcacctcaa tatgctaaac aaactgagaa taatctcagt ttgtttatac
    29641 tattctactg attcaccgtt agatgaaata acttccttat accagccaaa agattttttc
    29701 ggggaacgat tataacttcc cttcccatta tcatctttat ctacataaat aaagccataa
    29761 cgtttccgca tttcaccggt accagctgaa accaaatcaa tacatcccca tggagtataa
    29821 cccattaaat caacaccatc ttcaactaca gcctttttca tttcacgaat atgggcacct
    29881 agatattcaa ttctataatc atcatgtacc ataccatctg ctgcaacttt atctatagct
    29941 ccaaaaccat tttcaacaat aaagagtggt aagtgatagt ggtctgtaaa ccaatttaac
    30001 gcataacgca aaccttctgg atcaatttgc cactcccatt cagaagcctt aacataatta
    30061 tttttcacta aatcttctgt ttcaagataa tcaaaataag gattattttc acgatgagag
    30121 tcgatagcaa aggacatata gtaactgaaa tcaatgtaat ctacagtccc accaagtaaa
    30181 tcttctttat cctgggcagt aaaatcaact gaaatacctt ttcgttccca atacttgaaa
    30241 atatgctcag gatatttacc taaaacatgc acatcagcaa aataataacg cttttgcata
    30301 gctttcattg ccattaagat atccttagga ttgcaagtaa ctggataaat tggacacatc
    30361 gcaatcatac aacctatttg aaaatctgga ttaatctcat gaccaatttt tacagctcgt
    30421 gcagaagcaa ctaattcgta atgtgctgct tgatacataa ttgcttctct attatcacct
    30481 tcctcatata caatacctga gttagtaaat ggtgcaaaat cttcctgata attcgcttga
    30541 ttattgattt cattgaaagt catccaatat ttaaccttat ctttgtaacg tttaaatacg
    30601 acttctgcaa aacgagcaaa gaaatcaatc aatttcctat ttttccaacc accatattcg
    30661 gtcactaagt gataaggcat ttcaaaatga gatagagtga tgacaggttc aataccattc
    30721 tttaagcatt catcaaaaag attatcataa aactgtaatc cttcttcatt cggctctaac
    30781 tcatcacctt ttggaaagat acgtgtccat gcaagagagg tacggaagca cttgaatccc
    30841 atttcagcaa aaagtgctat atcttcttta taacgatgat aaaaatctat cgcctcatga
    30901 tttggataat atttaccctc taaaactccc aaagtaattt cacgagctac tccatgacga
    30961 ccagcagtca taacatcagc aacactaatt cccttgccac cttcttgcca tccaccttca
    31021 agttgatgag cagcaacagc accaccccat aaaaatccat ctttaaaagt agtcatcttt
    31081 tttcctcctg actttgatac tcttattata aacctcaaac caaaagatga aaacgtattc
    31141 tttttcctta ttattaagga aagaagtaat ttttaatgga aatagaacaa tatcttcttg
    31201 tattctcgta atgatatctt tacgattttc aatactttca aactacaaaa actctcacaa
    31261 taattctaat ttcctgtgtc tataaacgac ttatcgcttt ctggcatccc agaatcatct
    31321 tctatataac gttcaacttg catctgcaag tgatattttt ttcttaaatc taagattttc
    31381 tgcattgtct ttgattgatg atgcttatct aaagcttctt gatttatcca ctgatcaata
    31441 aggagaatag ttccctcttt ttcaattg
//
LOCUS       DAVDFK010000020        31310 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.20, whole genome shotgun sequence.
ACCESSION   DAVDFK010000020 DAVDFK010000000
VERSION     DAVDFK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.20"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(1..483)
                     /locus_tag="VUR04_001204"
                     /pseudo
     CDS             complement(1..483)
                     /locus_tag="VUR04_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            971..1090
                     /locus_tag="VUR04_001205"
     CDS             971..1090
                     /locus_tag="VUR04_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET5341102.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(1186..2532)
                     /gene="glnA"
                     /locus_tag="VUR04_001206"
     CDS             complement(1186..2532)
                     /gene="glnA"
                     /locus_tag="VUR04_001206"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET5341103.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2569..2925)
                     /gene="glnR"
                     /locus_tag="VUR04_001207"
     CDS             complement(2569..2925)
                     /gene="glnR"
                     /locus_tag="VUR04_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET5341104.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3002..3529)
                     /locus_tag="VUR04_001208"
     CDS             complement(3002..3529)
                     /locus_tag="VUR04_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET5341105.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIINLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3665..4861)
                     /locus_tag="VUR04_001209"
     CDS             complement(3665..4861)
                     /locus_tag="VUR04_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET5341106.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKALPGL
                     AALTEK"
     gene            complement(4951..9930)
                     /locus_tag="VUR04_001210"
     CDS             complement(4951..9930)
                     /locus_tag="VUR04_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET5341107.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSRANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAEEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            10223..11854
                     /locus_tag="VUR04_001211"
     CDS             10223..11854
                     /locus_tag="VUR04_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET5341108.1"
                     /translation="MSINWQEILFNFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(12413..14020)
                     /locus_tag="VUR04_001212"
     CDS             complement(12413..14020)
                     /locus_tag="VUR04_001212"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET5341109.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14410..14997)
                     /locus_tag="VUR04_001213"
     CDS             complement(14410..14997)
                     /locus_tag="VUR04_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET5341110.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15125..15574)
                     /locus_tag="VUR04_001214"
     CDS             complement(15125..15574)
                     /locus_tag="VUR04_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341111.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15579..15968)
                     /locus_tag="VUR04_001215"
     CDS             complement(15579..15968)
                     /locus_tag="VUR04_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET5341112.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15996..16622)
                     /locus_tag="VUR04_001216"
     CDS             complement(15996..16622)
                     /locus_tag="VUR04_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET5341113.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16636..17199)
                     /locus_tag="VUR04_001217"
     CDS             complement(16636..17199)
                     /locus_tag="VUR04_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5341114.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17364..17608)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17662..18165)
                     /locus_tag="VUR04_001218"
     CDS             complement(17662..18165)
                     /locus_tag="VUR04_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET5341115.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18358..19188)
                     /locus_tag="VUR04_001219"
     CDS             complement(18358..19188)
                     /locus_tag="VUR04_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET5341116.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            complement(19173..20855)
                     /locus_tag="VUR04_001220"
     CDS             complement(19173..20855)
                     /locus_tag="VUR04_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341117.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQEIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQIQLQTELVKETPALQSLFILEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWKKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
     gene            complement(20957..21214)
                     /locus_tag="VUR04_001221"
     CDS             complement(20957..21214)
                     /locus_tag="VUR04_001221"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341118.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(21221..21769)
                     /locus_tag="VUR04_001222"
     CDS             complement(21221..21769)
                     /locus_tag="VUR04_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET5341119.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMFNIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21784..22632)
                     /locus_tag="VUR04_001223"
     CDS             complement(21784..22632)
                     /locus_tag="VUR04_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET5341120.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     DQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22821..24170
                     /gene="trkA"
                     /locus_tag="VUR04_001224"
     CDS             22821..24170
                     /gene="trkA"
                     /locus_tag="VUR04_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET5341121.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            24174..25613
                     /locus_tag="VUR04_001225"
     CDS             24174..25613
                     /locus_tag="VUR04_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET5341122.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25739..26197)
                     /locus_tag="VUR04_001226"
     CDS             complement(25739..26197)
                     /locus_tag="VUR04_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
                     /protein_id="HET5341123.1"
                     /translation="MEVVLFSYCLNMRYLLQVIDIASSNDIILEEDTSEIMPGEIDVI
                     KSKELKVLVLCAGSGTSAQLANAINEGTQLAEVRVIANSGAYGAHYDIMGVYDLIILA
                     PQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            26758..26928
                     /locus_tag="VUR04_001227"
     CDS             26758..26928
                     /locus_tag="VUR04_001227"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341124.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            27540..27824
                     /locus_tag="VUR04_001228"
     CDS             27540..27824
                     /locus_tag="VUR04_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341125.1"
                     /translation="MVWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            27817..28065
                     /locus_tag="VUR04_001229"
     CDS             27817..28065
                     /locus_tag="VUR04_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341126.1"
                     /translation="MDKMKPVFQALNKELIQENLTLIIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            28161..28379
                     /locus_tag="VUR04_001230"
     CDS             28161..28379
                     /locus_tag="VUR04_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341127.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28747..31071)
                     /gene="pflB"
                     /locus_tag="VUR04_001231"
     CDS             complement(28747..31071)
                     /gene="pflB"
                     /locus_tag="VUR04_001231"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET5341128.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT         9214 a         6726 c         5715 g         9655 t
ORIGIN      
        1 aattaataat agattaaaat tataatcatt gattgcagga taacttgttc cagtagattt
       61 attattaaca cgattgataa aattatctga taataaataa tatttcaaat atgtttcgtt
      121 aagtaaagta tccaaaacaa taaatgctgt actagctatc aaatactctt taagttctct
      181 aactacagca atatttttta gatatggtct aactgttgaa aataagacac tattctgcga
      241 aactaatttt ctagcacggg aaggcgcttg ttcaggtgaa agatattgta gatttttgta
      301 gttgattatg ttcttttttc tatcaatact agacgtatct atatacctaa aggatttctc
      361 tggcttattt tgcccaaaat tccaataaat tgattttatc ctcacccact cccaagtatc
      421 aggaatatca taaggaacat caatttcttg agtacttcca tcagcaaact tcccataatg
      481 tttcttatgt gcttcaagta tataaaaagg cgtaaaaata cgcctataga taatggggtt
      541 gaaataggtt tattgttgat gagattgtag ataattcaat tttttacttc caatcgaata
      601 ttcaaaacct ccaccttttc tgcctgtaat tgttcatcat aaaattcaat atcttcagga
      661 ttttcccctt ggcaacctcg gcagaaatat tcttccgctc gatcaggatt caaaaatcga
      721 caagcacaaa caaaacagtc gccatcatca tttattgaga taatatagta gattgaaata
      781 agatgtaaac aaatcgatta ggaaagttaa attagtttct agaaattttt agcagatgta
      841 gtgtactatt ctagtctcaa tttactatgg cttcaaatat atctttcgaa aaaatattta
      901 cagatgtgta attttgaagc ttgcaaaagt tagtaaactt gtagatttcg atttgaagta
      961 acttgttttc ttgcccgata ttgtttttga aattgaattt ttccatagtg actccttaat
     1021 tttcttctac acgtctgatg ataaatctaa ttcgcaaaag agtcaagagg atttttcgaa
     1081 aaataaatag cgaccgaaat cgctatttta agggttatag gtatttgatg gcttagactg
     1141 ctgtgtgact gtttacccac aggcaatctt tcttctatat tagtattagt aaaggtctaa
     1201 ataattatca atttcccatt gtgaaacgaa ggttgcataa cttgcccatt cgattcgttt
     1261 ggcttcaagg aagctagtat agatgtgatc tccgagagca gctttaacca cttcatcttc
     1321 tgtcaaagct ttcaaagcgt tgtgaagagt tgatggaagg tctgtaatac cagcttcctt
     1381 gcgctcttct gctgtcatga tgtagatatt ttcttcgata ggagctggtg cttcgatttt
     1441 attttcaata ccatacaaac caacttccaa aagaacagcc atagcaacgt aagggttcgc
     1501 cattggatcc actgaacgca actcaagacg agttcccata ccacgtgaag caggtacgcg
     1561 cacaagtggc gaacggttac gaccagccca agcaatgtaa acaggcgctt cataacctgg
     1621 aaccaaacgt ttgtatgagt taactgttgg gttcatgatg gcagtatagt tgtaagcatg
     1681 cttgatcaaa ccgcctagga aatggtaagc tgtttctgac aactgcattc cttttggatc
     1741 atttggatca aagaaggcgt tatttccttc tgcatcaaac aaggacatat tacagtgcat
     1801 acctgatcca gcaataccaa attttggctt cgccataaat gttgcgtaaa gtccgtgttt
     1861 gcgagcaatg gttttaacaa caagcttaaa gatttgaatc ttatcacaag cacggagaac
     1921 ttcatcgtac ttaaagtcaa tctcatgctg tccaaccgca acctcgtggt gactcgcttc
     1981 tacttcaaat cccattttgg tcaagacatt cacaatctca cgacgtgtgt tgtccgcaag
     2041 gtcagtaggt gccaaatcaa agtagccacc cttgtcattc acttcaagtg ttgggtcccc
     2101 attttcatcc aacttaaata ggaagaattc tggctctgga ccaaggttga aggatttgaa
     2161 tccaacttct tccatgtgac gaagagctcg tttcaaatta ccacgagggt cccccgcaaa
     2221 tggttcacct tctgttgtat agacatcaca gatcagacct gcaacacttc cattttcatc
     2281 tccccaaggg aagactgtcc atgtatccaa gtccggatac aagtacatat ccgactcatt
     2341 gatacgtaca aaaccttcaa tagaagatcc atcaaacata accttgttcg acaagacctt
     2401 atctaactgt tcatctgtag caggaatttc gacgtttttc atggttccca aaatatctga
     2461 gaacataaga cgaataaagg taacattttt ttccttgact tcacgacgaa tatctgcagc
     2521 tgtgattggc ataagttttc tccttaatct atgactactt gcggttgcct aaccgcgacc
     2581 aaaaggtgac tgtactgaag caaaacgccc ctgttggagg agttcattgt gaagtgcacg
     2641 acgtacttca gtctgactaa ccgctttctt ggatttcgct tcacgttcag catatttttt
     2701 cttaatggca gcgatattat aaccttcaga gatataatct ttgatttcaa gcagacgatc
     2761 catgtcattc aaggaataca tgcgacgatt tccttcgttt cgatcgggct tgatcaactc
     2821 ttgatcttca taataacgaa tctgacgcgc cgatagatcg gtcaacttca taacactgcc
     2881 gataggaaaa acagccatat ttcggcgaaa ttctttttcc ttcatttaca atttccttct
     2941 ttctgtctat tatagtctaa aaaaagacaa acgtcaattg ataatgttat aaaatgtaac
     3001 attatttttc ttttttctct aaaaagagac gaatacgatc aatatcgtaa tttacgataa
     3061 ttgcgacaaa aactcccata aacgtttctg atacacgcac aaacacgtac gaaattgtct
     3121 caccacttgg aattgatagg ttaatgatta acatagctgc tacaccacca ataacccctg
     3181 ctttgttatt catggctaca tttgtcataa tggttaacat ggtgcagatt ggaacaacta
     3241 ccaaggtcac ccaaaaggct tcgtggaaaa aggtatttaa taagaagaag accaaggcat
     3301 agagtccacc gatactattt cctagaatac gcgaagtccc aaaatgaaca ctctcatcaa
     3361 aactctccct caggctaaaa acggctgtca aagcaccaat ttgaagacct ttccagccaa
     3421 aaaagccaaa aatcaagaga actagaaaaa cagcaatacc tgttttaaag gttcgcatac
     3481 caagtttgaa ctgggattta tcgaatttat attttttaaa ataactcata atctcaactt
     3541 tctatttcca ttttatcata aatcggtgat ttttatgagt aatagttgag aggaagcgtt
     3601 tttattttaa gcaaaagaaa agaggaactt tcatccctct cttctttgat ttatttataa
     3661 aatcttattt ttctgtcaag gctgcaagtc ctggaagagc cttaccttca agaagttcca
     3721 ttgatgctcc accacccgta ctaatccatg agaacttgtc tgcacggcca aggttaatcg
     3781 ctgcggcagc tgagtcacca ccaccgatga ttgatttaac tcctggttgt ttcacgatag
     3841 cgtccatcac accgattgta ccagcttgga aatctgggtt ttcaaataca cccataggtc
     3901 cgttccatac aactgttttg gcaccagtca aagcttcgtc aaatttggcg atagattttg
     3961 gaccgatgtc aagaccaagg aagccttcag aaactgcttc accttcagtg tcacgcactt
     4021 cagtgtaacc agcaaatgcg ttagcttctt ttgagtcaac tggcaagatc aatttaccat
     4081 ttgctttttc aagaagagct ttcgcaacat ccaatttgtc ttcttctaca agtgagttac
     4141 cgatttcgat accttgtgct ttgtagaatg tgtaagtcat cccaccaccg ataaggactt
     4201 tatcagcttt ttcaagcaag ttttcgataa caccgatctt gtctgaaact tttgaaccac
     4261 caaggatagc cacgaatgga cgttctggag tttcaactgc ttcttggatg taggcaattt
     4321 cgttttcaag aaggaaacca gcaactgctt tttcaacgtt tgctgagata ccaacgttag
     4381 atgcgtgtgc acggtgagct gtaccgaatg catcgtttac gaagatacca tctccaagtg
     4441 atgcccagta tttaccaagt tcaggatcgt ttttagattc tttcttgccg tcaacatctt
     4501 cgtaacgagt gttttcaacc aagagaactt gtccatcttc aagagcgttg attgccgctt
     4561 ccaattcagc accacgagtg acacctggga aaacaacatc ttgaccaagt tttgctgcca
     4621 agtcagctgc tacaggagca agtgatttac cagctttatc agcttcttct ttcacacgtc
     4681 caaggtgaga gaaaagaatt gcacgtccac cttgttcgat gatgtactta atagttggaa
     4741 gagctgctgt gatacggtta tcgttagtga ttacgccatc tttcaatggt acgttgaagt
     4801 caacacgaac gaggactttt ttacctttca agtcaacgtc tttaacagta agttttgcca
     4861 tgttacaaaa actcctttat ttattttatt cgaaactatt atatcacact ttggaaatat
     4921 aaggaaagat ttcacaagat ttttcgatat ttaatcttta tcttctcttt tccgtctcaa
     4981 ggtcaaggct aaactagcaa gaccaaggct ggctaagcct gctattaggg cttcattagc
     5041 atcagctgtt cctgtatttg gcaattgttt gcttgcttct tctgatttaa ctgctgtatt
     5101 ttgagctggt ttttcctgtg tagctactac tgctggtact gtttttactt ttgttccaat
     5161 ttcaacaatt tctggaatcg cttcttggat gacttctgtt gaacgaagac gacgctgacc
     5221 gttttcatca acttcaaaga catgtcttaa cagtccatct cgtccctgta tgatgactcg
     5281 ttgttcccca actagcatct cagcattttc atgctcttga cgatgaaagg caaccttttc
     5341 ctcttgaact tccaatttag gagccttttg ttgatcagaa gccggttgat aagtaggttt
     5401 tggaaggact gtgttttgtg gtgctggttt agcaggttgt ggtttttcag cagattcata
     5461 aacaaaggca taatgagtaa agtgaggtgc tgtaaagata acatgactat ccgtttgttc
     5521 aaaagccaat tctactgcct ctttgccttc aggtaagaaa aatactttct taactttctt
     5581 atctttttca attgggattt tcacaataga agcataagag agatcaacat cttgaccttt
     5641 ttcatccaaa ccttctattt caaagacatg agcatcttct ccagcaaagt atttcttctc
     5701 ttcagcactt gcttgaacac gctctacttt caaacccttg atgacagtct tctctttatt
     5761 tgagaagtgt acttcaacac ctgttttact atcagaaaag actgctgact tgtcttcttt
     5821 caataaagca accagatctt ttagactctg tttcgctgtt gcaagctctt ctggactcaa
     5881 atctactttt tcaaccaagg ccttgttttt ctcaagaagc ggagctaggg cagaacctga
     5941 aggatggttt ggtttggcag ccaagagttc ttgaacctca cctgttaagc gatcaagttc
     6001 tgtcttttct tccttaaatt tctcttgacc attcagagct ttatgagctt ctgtcaattt
     6061 attaagtcgg tcattgactt gatcttgggt gctagtttca tggtctttca acacttgttc
     6121 ggccgcttca attgctttca agaaagcttc ttttacttct ggtgaagcaa agttatagac
     6181 caccttgttc ttagcagctt caacctctgc taatttttgt ttgaggtact catcgttcaa
     6241 tgctgctttt ggagatacca aaacatcaaa gttgacttca tgaccttggt aacgaagcgt
     6301 caaggtttga cgaccagtct tttgagcatc gtaaccagaa atttcaactc cctcatcagt
     6361 aaaggaatgt tcttccatgg tgtcattgct ataagccact gcaaagcgtc cttcagacaa
     6421 gtctaagcta tcaccaacta ggtaatcttt tttcggttcc tgacttactt caattcccaa
     6481 aatagttttc ggacttgctt catcttggcc agtgacagtc actgacaaat tagcatttac
     6541 tggttgtccc aaatattgga gagtaagatt ctgttctccc ttatgatgcg tatcaaaacc
     6601 tgatactgat acacctgcgt gagttaggcg aatgagttcg tcctcagttc ctccttcata
     6661 ctgaactcga agaacaccac ctctaaggtc caaatcctcc ccttcggcgt agcttgtttt
     6721 cttaggtcct gtttctaggc tgactgactt gattcttctg tcatcttttg gaacggaaac
     6781 tgctaggaca ttactaattt ccttgcctgg caactgggta cgataataaa gaagaccaga
     6841 ttgatttgtc aaatccaatg gtgcacttgc taggtctcct ccaacttcgc tcttcaaggt
     6901 tgcaagcgga gtttgagaat ttggattatc ataaacggta atagttgctc cagccggtac
     6961 atctgcaaag ccaacttgta ccttgttatt gcctagagaa cgggctgcag ccttggccat
     7021 cggaatattg acactctcag tatcaagctt ttcatacatt ttccagttat agatacgaat
     7081 agccttccat ggagttccat tgtcagaagt gacaacattc aagcgccagt cttgagcagt
     7141 gattggttta tcaagagtga tatctgtcac gtgtgctttg ttaccacgga cttccttagc
     7201 tagcttccac tcaccatctg catctttata ataaaggtca aagtctttgg tgttcatcaa
     7261 gccatcgtta acagactcac caccagcccc tgcatgatcc atgacccatc taacaacggt
     7321 acgtggcttg gtcaaacgaa tatccacact accactcaac tgagctgaag accatttatc
     7381 tgacaagcta gtaatggtac cgttcaacat accttcaata ccttctccac cttcagtctt
     7441 agggaaagta ctatcaataa ctgttgcacc tggaacgata ttttcagcta gtggttttgg
     7501 taggctggta tcttttacag tcatacccca atcaaaggtt gtggttgcag cttctgaacg
     7561 aactccattt ttaccgactg ctacaacctt cagttcttga gttgtaccct gagcacttgc
     7621 tgagcggcta acttttggta gataaatagt tgtagaagat gagccagtta gtaatttcca
     7681 gctgtctcca tctttttcat aaacttcata gaaatctgca tccttgttgc ctttaaattg
     7741 cacaactgct tccgcttctt gggcattttt aagagattgt ttcactacag aaaagcttgt
     7801 cggcgattgt ggctcttggt gattgtccga gatagttaat tgtccgaggt tgaactgata
     7861 atcttttaca gcaccttcat gctcgaaaaa tagtttgact gcatagatgg ttttacccgc
     7921 tagtgagctg agatcaaatt cttcatttgt ccagttgtca gaaagggtta gctctttcca
     7981 tgcatctgca tcatcgaatt tgtagtctgg agttgtagag aatgccatat aaactttaga
     8041 accttttcct cccttgtggg caacacgaag tttggtcttc tcagttactt ctaacttagt
     8101 agaataaagt ctcacatcct gatctgtctt accagctaca tcaccagaga atttaaggga
     8161 atttccgcca ttataggcat ctgtaaaatc atattctgca cgaagttttt cccctgttga
     8221 agtctgccac cagcgccatg ttggaagaac acctgatact gaacgataat tccactcaga
     8281 atccttagaa accttaccat ctacgaacca ttttttacca tgacctgtat taaaagaagt
     8341 agtaaaagta ttacctaccg ctggcgtacg gtccgcaact aggttagcaa taccatacca
     8401 atctttgtca cctggttttt ggccagtagg gtctccttga taacctgtaa agaagatatc
     8461 ttcattttta tgataatctt caccagtttt tcctaaactt gtaatggtat ctggggcaaa
     8521 taaaccaaga gaaaggcgca atttcccatt ttcgtctaaa atgtcattcc acttaacctt
     8581 tgtcttgtag gaaccaccct gttgcaattc caaacctgca aatacatcat aaggattacg
     8641 accaatccag ttggcagttg caatagtgta atcattttta gccttatccc agttaaagtt
     8701 agcaaagaag ttatctgccg gaaccttatc tccttctggt tgcatgaatt ggtagttgta
     8761 ttctcccaaa ccatcttgat ggtaacgtcc atagttatat gtcatggcat cataccaaga
     8821 atacttgatt ggatggttta ccttagcagc atattccttg ctatagagca taaactggcg
     8881 catcttttct ccaagaggtt taaccaaatc tccagttgtt tcttggttga tgaaatagcc
     8941 atcatagcca taatactttg ccatgtctac caatttacga gcaattggga agctaccatc
     9001 tgcgtcttgc ttcaaagctt cagcaaatct ttcttgatct gcaatactat tagaccagtt
     9061 gaagaagagt gtaccgtata caggaacccc gttacggtga cctgcatcaa taacgtcagg
     9121 agttggtacg agaccttccc agaagaccat tgaatctaga tattgccaat agtcaaaagc
     9181 ataggccttg aactcttctc caccaacaga agcatggtct tttgctttag aattagtgtt
     9241 tgataaggct tgaacttttg cttccttgct agctttttca ttgactaaat gacctgtccg
     9301 acgtgaagcg aggacaacag atccgcggtt aatagcatca tcttcacgag cacctggttc
     9361 ccatttcaac aattcttccc aagaattaaa tttgatttcc tttggtttta atgttttttc
     9421 tgtattttta gggacatctg gctggacttc tttttcagtc ttattagctt cttctgctgg
     9481 tttagactca tccccttggt tagttgcttc gggctttgct tctgtttcct tgtcagactt
     9541 aggttttgct tctgcagatg gtgtttctgc aaccacctca cttgcttttt cctctggttt
     9601 agctgcgcta gctgcttctg cagtttcagt agttgcagct tcattgcttg ctggcgaagc
     9661 agtttcagat gctgtcgcta ctccttctgc cttttctagc ttgttttctc tagcatgttc
     9721 cccttcattc tgcttatcag cttcattggt cgaatgctca ctctctcctg aaacaagctc
     9781 tgtattagct ctgctatttt caggaactgc agtttcttca gccaaggctg gaccagcaaa
     9841 taaaacagca ccaatcatca gcgagcaggc tcctactgat aacttacgaa tactgtaacg
     9901 acaacgtctt tcaaaaaatg gattcttcat tttctcctcc taaaagattg attttgttgt
     9961 tttcaagaaa gcgctttata ttctgtagtt ttttatcaaa ctctagaacc atgataatca
    10021 catttttatc ctaaaacatt tttagacaaa aaacaataac tgtttgcaca aatctaaaat
    10081 aaggttaaaa actcttaaaa ataatacact tatcaattat aattttcttt tacaaacttg
    10141 acattaacac ttgttagatt tacttttatc ctttaaaata gaataggaga tattccgcga
    10201 ttatttttcg gaggaaaaag aaatgtccat taattggcag gaaattttat ttaacttttt
    10261 aggtggtctg gggctattct tatatagtat caagaccatg ggagacggtt tgcaacaagc
    10321 tgctggagat cgccttcgtt tttacattga caaatatact agtaatcctt tctttggagt
    10381 tctggttggt attgggatga ctgctctaat tcagtctagt tctggtgtaa cagttatcac
    10441 agtcggcctg gtcagtgccg gtctcttaac cttacgtcag gctatcggga ttgtcatggg
    10501 tgctaatatt gggacaactg tcacatcctt tctcatcggt tttaaattag gtaactatgc
    10561 cctacctatg ctctttatcg gtgccgtctg tctctttttt acgaaaaatc ggacagtcaa
    10621 taatatcgga cgcatcctct ttggtgtcgg tggtatcttt tttgccctca atctcatgag
    10681 cggcgcaatg gctccactca aggatttaca ggtctttaag gactatatga ttgagctaag
    10741 taagaatcct gttttgggtg tctttgtcgg tactggcttg accttgctaa ttcaagcttc
    10801 ttcggctacc attgggattt tacaaaacct ctacgccggc aatctaattg acctacaggg
    10861 agctttgcca gttctatttg gtgacaatat cgggacaacc attacagcca tcattgcctc
    10921 tttaggggct aatattgcag ctaaacgggt agcaggagct catgttgcct tcaacgttat
    10981 cggaacagtt gtctgcgtta tttttctagt tccttttact gtcctgattc attggtttga
    11041 agctacgcta aatctagcac cggaaatgac catcgccttt gctcacggaa cctttaatat
    11101 taccaacacc attgtccaat ttccatttat cggagctctg gcttactttg taaccaagat
    11161 tattcctgga gaggacgagg ttgtcaaata cgaaccctta tatcttgatg aacatttcat
    11221 caaacaggcc ccatctatcg ctctaggaaa tgctaagaaa gagctcttgc acttaggaaa
    11281 ctacgctgct aaagcctttg acctttccta taagtacatc attgacttgg atgaaaaagt
    11341 tgctgaaaaa gggcataaaa ccgaagaagc aattaacacc atcgatgagc aattaacacg
    11401 ttatctcatt gccctttcaa gcgaagctct cagccaaaaa gaaagtgaag tgcttaccaa
    11461 tatccttgat tcctcccgtg atttggaacg gattggagac cacacggagg ctctactcaa
    11521 tctgactgac tatcttcaac ggaaaaatgt tgaattttct gatgccgcct tgaaagaatt
    11581 agaggaagtt taccgccaaa ctagtgactt tatcaaagat gctctggata gtgtggaaaa
    11641 caatgatatt gaaaaagcac gcagtcttgt agaacgtcat gaagcaatca ataagataga
    11701 acgtgttctc agaaaaaccc acatcaaacg cctcaacaaa ggcgaatgtt caacacaagc
    11761 tggggtcaac tttatcgaca tcatctcaca ctacactcgt gtatcagacc acgctatgaa
    11821 ccttgctgaa aaggtttttg cagaacaaat ctaagaacca agaagctatc catcataatt
    11881 ggatgacttt ttactttttc ctaagcaaga ctaggctgaa tgaaactgaa agagtattct
    11941 gcagatatat agtatattga aactagaata gtacacctct atttctaaaa cattgttaga
    12001 aatcgatttg actgtcctga tcgatttgtc ctgttcttat ttccttttac tatagtggat
    12061 taaattaaaa aagtataatg tattgaatct ataacagtac atcttgactg ctaaaatatt
    12121 tctataaatt aatttgactt tcctgataga gatgttcaca tcttatttca attcactata
    12181 caatccagtt cctaaaactt tgctagaaat tgatttggct ttccgaatta atttgttcaa
    12241 attttatttc atttcaatat actgataaat ccattcacta gcacagggca agagggagtc
    12301 gctatttatt tcaacggtag caggtacata cagaggactc ctacctcaga tatactgcaa
    12361 tatcatcgta tgcaaaaaac ctctgagatt tttctcaaag gttctgattt tgctaattgc
    12421 tgttctcaac cgctgcagta acaaaggcag tgtagagttc ttctggtcgg tttggacggc
    12481 ttgacagttc agggtgatac tgacaagcta caaagaattt attttcagga atttccacga
    12541 tttctaccaa acgattgtct ggagaaactc ctgaaaagac aaaacctgct gcctcaaact
    12601 gctcacggaa ggcattatta aactcataac ggtgacggtg acggcgttgc accacttctt
    12661 gattgtgata agcagcagca gccttagagc cacgtttcaa cttagacgga taaagtccca
    12721 aacgaagggt tccacccata tcctcaatat caatctgatc acgcatgata tcaatgatag
    12781 ggtattttgt ttctggtgca agctctgcag aattggcacc ttcaagacct aaaacgtgac
    12841 gagcaaactc gatacatgtc aactgcattc ccaagcagac tcccaacatt ggaacatcat
    12901 tttcacgcgc atagcggatg gcttggattt tcccttctgt accacgttga ccaaaaccac
    12961 ctggtacgat gatcccgtcc gcatcagaca agagttctgc tacattctct gctgtcacat
    13021 cattggcatt gacccaattg attttaactt ctacatcatt gacatagcca gagtgtttca
    13081 aggcttcgac cactgagata taggcatctt gcaactccac atacttacca acaagggaaa
    13141 tcttaacttg tttcttgagg ttcatgacct tgtccaccat ggctgaccat tctgtcatat
    13201 ccgctgctgg tgcgtctaat ttcaaatgat cacaaacaat ttggtccatc ccttgtgcct
    13261 gcaagttcag tggaatttgg taaaggtgtt caacatccaa cgattcgata acggcttctg
    13321 gtgccacatc acagaactgg gccagtttat ttttaattcc ttgaccagct ggctcttctg
    13381 tacgaataac caacatattt ggttggattc ccaagccacg caattctttg acagagtgtt
    13441 gggttggttt ggttttcatt tcaccagcag ccttgaggta aggaagcaag gttgtatgga
    13501 tatacatgac attatccgca cccacatctg ccttcatctg acgaagagcc tctaggaatg
    13561 gcaaggactc gatatctcct actgttccac caacctctgt gataatgaca tcagagtcgg
    13621 tcgttagagc ggcacgcttg attttttctt tcaaagcatc tgtgatatga ggaatgactt
    13681 gaacagttgc cccaaggtat tctccacggc gttctttacg aagaacttca ctgtaaattt
    13741 tcccagttgt cacgttggaa tatttgttga gattgatatc gatgaaacgt tcatagtgac
    13801 ccaagtccaa atctgtctca gctccgtcat ctgtcacaaa aacttccccg tgctggtaag
    13861 gactcatggt tcccggatca atattgatat aagggtcaaa cttttgaatg gttactttga
    13921 gaccacgatt tttcaagaga cggcctagac tcgctgccac aatccctttc ccaatagacg
    13981 ataccacacc accagttaca aaaatatatt tcgtagacat agattcctct ttctaaaatg
    14041 ctcaaggtct tgttaactac gaggggatat agaaaacaag accctactaa taagaataat
    14101 ctgggacgac tgcaccagat tcacaactaa tactcttcga aaatctcttc aaaccgcgtc
    14161 aacgtcgcct tgccgtagat atgtgttcct gactttgtca gtcttatcta caacctcaaa
    14221 acagtgtttt gagcagccta cggctagttt cctagcttgc actttgattt tcattgagta
    14281 taaaatacaa gaagataact tcttgaaaaa acaaaaatag ctccctaaga actagggagc
    14341 cccgacctct aaaagaggtg cccaaacaat atgataccta aaaataggat aattgtcaat
    14401 agctaactct tattcctcgc tggtttcagc gtcgtcatct gaaaactcgt cgtcgtcttc
    14461 gttgagatcc acatcttctc ccaagtcatc tggagcgatt tcgttgattt ctgcatcata
    14521 agcttccact tcattttttt catcatctgg attttcatca tcgtatgaaa gagctggatc
    14581 tgcttcgtat gcatcttcgt cttctggatc atctgcattg tagtcaatgg catctgaatc
    14641 accatccata aaggcattga cacgtttttt cttagctttt ggtgctactt catcgtcgtc
    14701 attttcttca agagcgatga tttcttcgtc gatttcgtcc acaccatacc atgaacgaag
    14761 accccatttg ttgtccccaa gtgagatgaa gctaccgtca aagttcaact ctgtgtagaa
    14821 caaaggcaaa gcttcgcgga tatcgctgtt tgatgttcca aggtagtttt gaatttcgtt
    14881 tacaagatcg ctaaaatgca tctcatgatc gcgaccacga agttccaaga tagcacgcgc
    14941 tacctcaatc atagatagtt cacttttttc ttgcccagca aatacttcta attccaaagc
    15001 gtttctcctc atttatacta ctatcgccag agcgaacaga ctctgacctc attttatcat
    15061 ttactcttta ttttacgata attttgcgga atagtcaaag gttaaggggg agaaagtggc
    15121 aggattagac taattccaat ataaaactcc ttcctttttc tgttgctcca ttttccacaa
    15181 atccaagcga cttgaaacac ctcctagaag catgattgta ggtgtagatt tccttgactc
    15241 tcaattcttt ccatcctttt actcgagcca attcaatcaa agcacttaga atcttttttc
    15301 caagtcctcg atgttggtaa gcggaattcc caatcacaat ggggagatta tcctgagata
    15361 gtgtaatatc cccaattgga aaccattctc ccttctcctt gacttcaatc caaaaaagct
    15421 caccatgccg atccaaatag gaatacatgg cttccaaggt cgcttgactg taaggaagct
    15481 tcaccccatc tacgaggtaa accaagttca catcctgata ccaagcaaaa gcttcctcac
    15541 aataattgac cttataataa ggaacaaaac acaatgcact accttttcaa caaaagagtt
    15601 gctgcttgat taaaaccatc acaccagtta taccattttg cttcataccc atcttgagct
    15661 aggatacgat cttctaaatc aaaaacagag taaatctttc tttcctcgca agcttgcgca
    15721 tagagatgat atagttcatc accaccatct ctatcccact cagcagaaat cgtatcccga
    15781 cctgccaata aagcctgata agccctgtga tgcccatctg taatcagcaa acaatctcca
    15841 aaggcaagaa tactgattgg atcgacttgg attgtttctg ccgactggta aagcatctga
    15901 atatcttgca acttcttttc tgataaatat agttgagtcg gatgaagatc tgctatattg
    15961 actttcattt ctttctcctc aagggaattc gatactcact tctgtttgcc tttaaatcgc
    16021 cattggaagc ggagcttgtc atagaaggga aactcgataa acaggactcc caagcccaca
    16081 cagagactgg caaggacgtc tgatgggtaa tgaactccca gatagactct tgataccagc
    16141 acactgacta ggtagaggcc aaggacgatt tgtacgattt ttctccagac tggatcttta
    16201 atccgctgac taagaataac aatcaaagta cctaccatca aggttacagc cagagaatgc
    16261 ccacttggga aggaaaatcc cttctcctcc accagatgta agatatctgg ccgtgggcgc
    16321 tggtagatat ttttaaaggt cacgattaaa agacctgcca aagccagatt tcccagcatg
    16381 aagaaacttt ctatcttcca tcgcttacga taaaagacaa aagctgtaat gacaacccaa
    16441 gtgataatca ctgggatatc aatcagacgt gtgagggctc gaaaaagaat agtcaaataa
    16501 tctggtaagt ctcctcgaat ggcagtctga atcgattggt caaaattgac cagcgtttca
    16561 gggtaaaatt tgaccatgta gccaagaata acgaaaagta aaagggcaaa actgcccttc
    16621 attaaaaatg tttgtttatc tctcataatg ttttaaggtt ggtttcaaga gaacatacaa
    16681 caaccagaat gaaacggaaa agataacacc ttcaatcaag ttaaaaggta ataccatggt
    16741 cattaggtag ttggaaagtc ccaaaatttt tccaatatca aagttagcaa acttagcgta
    16801 caaaggaaca gcataaacat agttgagaac caacatggcc aaggttaaac caatagttcc
    16861 agctagagag cctagtagga aacgaagggt tgtccgttcc tttttccaaa tcaaagcaaa
    16921 tacgatgaca aaaactccca aagctacgat attcatcggc aaaccaatgt aagtattcac
    16981 tccttggctg ttaagaagca acttcaagag tgagcgaagc aagagcactc ctagagcagc
    17041 aggcaaatcc atgaccacca gacccacaag gactggcaag atactaaatt cgatcttgag
    17101 gaaagatgcc gctggtaaaa gcggaaagtc aaagtacatc agcacaaatg agatggctga
    17161 tagaattgca atggtcgaaa gtcgacgtgt gtttgtcata acaggttcct ccaattttct
    17221 ataaaatcag aagaagttgg aaaggattcc tctatctatt ctcacttttt atatcccaaa
    17281 agttccctct tactctatta aagaaaaaca aagcaagtgg ttacaatccg gctataaatc
    17341 tatcaaaaca gacaaagcta ttctttcgtc ttctcccatc cagactatac tgtcggttgt
    17401 ggaatctcac cacatcagct tgcgctcgcg gacttcttta aagagaaaga aatagagatt
    17461 tttcttttag actaggcgac aagctgtagg cataacttct ggttagttct ggttaggcaa
    17521 agcttgtcaa caaagtataa aaggaaaaga tcatttccta gttaaagtca ccgccggtcg
    17581 ggaatcacac cctgccctga agactctttt atcataacaa aaaacgcttg caagtgcaag
    17641 cattttgttc attttcattt tttatttcaa tttatccact tcataggtat ggacgagttc
    17701 aagacctgca aagttctgct ggcgaagagc ctcatagaca atcatgcaga cggtattaga
    17761 cacattgaga ctgcggacat gttcatcatt catgggaata cggagagcct tctcaggatg
    17821 ttctcgcata aaatcttcag gtaaaccctt gtcttcacgt ccaaagagaa aataatggtc
    17881 ctcgtcagtc gataaatcca cctcagaata gactttttcc gcgaatttcg aaatcagata
    17941 gagttttccc ttcatctgag atatgaaatc ttccaaactc tcgtaaaaat aaatctctag
    18001 cttatcccag taatccaatc cagcccgctt catcttgcgg tcatcaatag gaaagcccat
    18061 aggcttgatg atgtggaggg gagaattggt cgcagcgcaa gtacgcgcga tattgcccgt
    18121 attttgtgga atttgaggtt caaataatac aatgtgattt gtcatgactt gcttcctttc
    18181 accattgcaa aaaaatagcc acactgcccg gagtcaagct cagcaaacag cgtggttaag
    18241 gcatcgttaa cttacctcac aacaggtttg aagtaaatca gcgaaactac tttcttagta
    18301 taacactttc agaatcattg tcaatagaaa cgacttgatt ttttcaattt tttcaagcta
    18361 tttccaaggg ttgtaaaatc gtccctgatt ctgcaagata agtagtaaac tagctactaa
    18421 aaacaaggtt gccaagagca aggtaatata gtctcctttt ttcaaggcct gataactata
    18481 ccatgtgcgt tttttctctt tcccaaagcg tcgaagctcc atggcggtcg cgatggtatc
    18541 aatccgttct aacgagctaa aaatcaaggg agtaataatg agcagattgc ctttgattcg
    18601 ttgcataaga gaagctttct tggataattc catcccacgc gcttcctgag acatcttgat
    18661 ggtaaagaat tcttcctgca aatctggaat atagcgcaag gttagactga cagaataggc
    18721 aatcttgtaa ggcacaccaa tttgatttaa actggaagca aactgactag ggtgggttgt
    18781 catcaaaaag ataatagcca gaggaatagt gcaaaggtac ttaatagcca aatttagcag
    18841 ataaaagagc tcttgactgg tcagagtgta ggcaccgatt ccctgccaaa tcacacttct
    18901 ctctccgtaa agtccaaccc catactcggg agaaaagaga tagaccatca aaacgtttaa
    18961 aacggcaaat accgtcgcaa aaacagctac aaaggaaaca tctttaaaat ggatttctga
    19021 caaatagagg agaaagaccg aaaagatggc aatcagaaca agcagtctgg tatcatagct
    19081 aatcatggcc gccaatgaca cgagaatgaa aaagaggagt ttcccagcgc ctgacaagcg
    19141 atgaatcaca gtatctctat gctggtaacc gattaattta gcttgcatcc ttctctcctt
    19201 tctttgtaaa atgccgttaa agcaagtgga tccacgtcga gtttcttagc caagttgaag
    19261 atagaagtct cttttaggtt ggcttttact aacagctcag gattgctcaa cagactggct
    19321 ggaacagtat cggcaatcaa ttctccatcc accatgacaa ggacccggtc tgaataatcc
    19381 agcatcaatt gcatatcatg ggtaatcatg acaatggtat gccctttttg atgtaactct
    19441 tcgagaaatt ccataatctc agtatagttc ttctgatctt gacctgcagt cggttcatct
    19501 aggagaataa tttcagctcc taagaccaaa attgaagcaa tggtgacacg ttttttctga
    19561 ccaaatgaca gggcagaaat aggccaatta cggaattcat aaagcccaca gattttcaag
    19621 gtttcataga ctctcgtttc aatttccttc tcatccacac ctcgcaaacg gagccctaga
    19681 gccacctcat caaaaatcat attggttgaa atcatttgat taggattttg tagcacatat
    19741 cctactcgtt ccgcccgctc tgcaacagaa tcgcctttta tatcctgttt tttccaaaga
    19801 tagcgtcctt ccgtctgaat aaagctactt atagccttgg ctagagttga tttccctgct
    19861 ccattttttc cgacaatagc aatcttttca ccctttttaa tatctaaatg tagggatttt
    19921 aaaatcggtc tatcatcata agaaaaagat acttcctcta gtataaagag tgactgcaat
    19981 gctggggttt cttttaccag ttccgtctgt aactggattt gcccttttga gatagacaag
    20041 ttatccagat ctgctaattg ttcttccttg actaagtcca cacctaattg acggagagtg
    20101 gttagataaa ggggttctcg aattccattt tgagtcaata aatcagtcgc aagcaactgg
    20161 tcagggctcc cattaaaaag gatacgacca tcgtttatca agacaatccg atccacaggg
    20221 cgatgcagaa cgtcctccaa acggtgctcg ataatcagag tcgtcgtccc ctcttcctta
    20281 tgaatctggt caatcaattc gataatatcc tgacctgact tgggatctag attggcgagt
    20341 ggctcatcaa acaagagaat cggactttca tcaatcaaga caccagccag actgactcgc
    20401 tgcttttgtc cacctgacaa atcctgagga cgctgatcca gtaaaggaag aaggtccagc
    20461 ttttcagccc atttataaac acgacctttc atctcatcta gggctgtcac atcattttcc
    20521 agagcaaacg ccaaatcttc tgccacagac aagccaataa actgcccatc tgtatcctgc
    20581 aaaactgtgc taaccagatg agacttatca tagatgctca tatcaaaggc tacttgaccc
    20641 tttatcaaaa attctccata tgtctgaccc ttgtaaatat tgggaataat cccattcaaa
    20701 cactgaccca aggtagattt acctgatcca gatggtccaa caattaagac tttctctccc
    20761 ttgtaaatgg tcaagtctat ctcttgcaag gtcggttctt gttgtgtttc ataccggaaa
    20821 gagaaatcct tccactcaat tatagcttct ttcatcttac tctcttcatt cgcttcttag
    20881 acttctattt tatcataaat caagcccttc ttgcagtctc ttctcttaaa atcttagcgc
    20941 caaaaagatt cctatcctag cttacttgcc taactaatct ataaacatcg aaaaagacta
    21001 gttgcccagc cttccccatc attttatact cttcgaaaat ctcttcaaac cacgtcagct
    21061 tcgccttgcc gtaggtatgg ttactgactt cgtcagtttc atctacaacc tcaaaaccat
    21121 gttttgagct gacttcgtca gttctatcca caatctcaaa acactgtttt gagcaacctg
    21181 cggctagctt cctagtttgc tctttgattt tcattgagta ttagtccttt ttcaaacttc
    21241 ctgcacgagt ttgggttcct gcataggcaa gtaagagaag agttcctgca atagctacag
    21301 atacaccatt ggcaattccc gcaacaatcc cttgtgcaaa tactttttct gccgcttctt
    21361 gataaatcac aacatctcca agtggtgcca agacacccca aacaagggca tttgcaagta
    21421 gttgaatgag gttaaaaata agaatatctt tccagtcaaa aacaccattg atcacgcgaa
    21481 cgtactttct aaaaagtccc acaactaaac caaagagtcc gctagcgata atccaagtcc
    21541 accatagacc ataaccagca agagagtcct tgattgcatg accaatcaac ccgacaagca
    21601 aaccgataat cggtccaaaa ataatagaaa gtagcgcttg taccgcatac tgaagctgga
    21661 tgcttgtatt tggaacaggg gttggaatgt tgaacatccc gatgacgaca aagagggcag
    21721 cgccaattcc gacagcaaca acttgtttaa ttgtaaattt gatttccata ctattctcct
    21781 attttatcct tctattttct ttatttcaat ggtccaagat gaaccgacac ctacattata
    21841 ggccttggca aaggaacctt ggttgatagc caaacctaaa cgatagagag agttgatgta
    21901 aaggatgggt tgcccaattc tcacatctgc aaatgatttg ccatagacaa cctgattttg
    21961 atagaccagc atatcagcat gatagatggt cacttcaaaa cgatcaccaa attctggttc
    22021 caacttgtaa aattcttccc gtgtgataga ggtccaaagc gaaccgaaac gcacatccag
    22081 aatatcaatg gctcccttca ccagatgatc ttctatgatg gtcgctacga ctggaagctc
    22141 tacaatctgg tccacactga gctctggccc tacttcctca aaagtaatgt gaccactggc
    22201 cagtttagca ccagtatagg catagacatc acgaccgtgg aaggtataag aatgctctgt
    22261 gttttgacgc ctattggcca cctcagaaat ctcacgaatg gctacaatgc caacgtgttt
    22321 cttgataaag gaaagcgtcc cattatctgg cgtgacaatg tattgatttt ttgcagtctt
    22381 ggcaactaca ctcttacgtt tcgaaccgac acctggatcg acaaccgata caaacgtcgt
    22441 tccctcaggc cagtaatcca ccgtctgaaa gagacgatag ctcccctcaa aaatattata
    22501 aggtgtgata tcgtgcgtca agtgatggat ttttaaggtt ggagactctt ctaaagccac
    22561 tccaatcata gccgataccg caccatcaac cagaccaaag tctgattgta ataccagtaa
    22621 attattattc attttatctc cttgtatatc ctttatcata ccatatttca gagaaagtcg
    22681 ctaatagcta tttcaattgg ttagggtata gttttacctt atagcaaatt tcctactaaa
    22741 agttcttgtt attagctagt aggtgcattt tttcttgaaa aagggtatga tagttacatc
    22801 atgaaaaagt aggttttatt atgaaaatta tccttgtcgg agggggaaaa gttggttttg
    22861 ccctctgtcg ctccttggtt gcagaaaagc atgatgtttt gctgattgag caagacgaag
    22921 ctgttctcaa tcatattgtc agtcgctttg atatcattgg tatccttggt aacggggccg
    22981 attttgccat tcttgagcaa gccagcgtcc aagattgtga tatctttatc gccctgactg
    23041 agcacgatga agtcaacatg attgcagcag ttctagccaa gaaaatggga gctaaagaaa
    23101 ctatcgttcg ggtgcggaac cctgaatatt ctaactctta tttcaaggaa aagaatattc
    23161 tcggtttttc tcttatcgtt aatcctgagc tcttggctgc ccgcgctatc gcgaatatca
    23221 ttgacttccc caacgccctg tctgtcgaac gctttgctgg tggacgcgtt agcctcatgg
    23281 aatttgtcgt caagtccacc agcggtcttt gccaaatgcc catttctgat tttcgtaaaa
    23341 aatttggtaa tgtcattgtc tgtgcgatag agagggatca tcaaattatc attccaagcg
    23401 gtgacatgac tgtacaggat aaagatagaa tctttgtcac tggtaaccgt gtcgatatga
    23461 tactcttcca taattatttt aaatcacgcg ccgtgaagag ccttctcatc gttggggcag
    23521 gtagaattgc ctattatcta cttggtattc tcaaagatag tcgtatcgat acaaaagtca
    23581 ttgaaatcaa tcctgaaatc gccagcttct ttagcgagaa attcccaaat ctctacatcg
    23641 ttcaaggaga tggaaccgca aaagatatcc tgctggaaga aagtgctcaa cactatgatg
    23701 ccgttgcgac tctaacagga gtcgatgagg aaaatctgat tacatctatg ttccttgaca
    23761 gggtaggtgt acagaaaaat attactaagg tcaatcgtac cagtctcctc gagattatca
    23821 atgcgcctga tttttcaagt atcatcacac ctaaaagcat cgctgtagat acgattatgc
    23881 actttattcg tggtcgagtt aatgcccagt attcagacct tcaagccatg caccatctag
    23941 ccaatggcca aatcgaaacc ctgcaattcc atatcaagga agccaataaa atgactgcca
    24001 aacctctttc tcaactgaaa ttgaaaaaag gggttcttat tgcagccatt attcgaaagg
    24061 gcaagactat tttcccaact ggggaggata tgttggaagt tggagacaag ctcctagtaa
    24121 caaccttgtt gccaaacatc accaagattt atgacttgat tgcgaggtaa aaaatgaata
    24181 aaagtatgat tcgttacctc ctttcaaagt tacttttgat tgaagctgtt ctcctcttgg
    24241 ttcctgtggc tatcgctgtc tattaccgtg aatcgagcca agtctttacg gccctctttt
    24301 cgaccatagg gattctcgta ttgttaggcg gttcagggag tttacagaag ccaaaaaatc
    24361 aacggattta tgccaaggag ggagtcttga tcgttgccct ctgttggatc ctttggtctt
    24421 tctttggtgg tctccccttt gtcttttctg ggcaaatccc cagccttatt gatgcctttt
    24481 ttgaaattag ttctgggttt acaactactg gagcaagtat tttgaacgac atttcggttc
    24541 tcagccgttc cctcctcttc tggcgaagtt ttacccactt gattggaggg atgggagtgc
    24601 ttgtttttgc acttgctatt atggacaatg ccaaaaatag tcacctagaa gtaatgaagg
    24661 ctgaggttcc tggtcctgtc tttggtaagg ttgtatccaa attaaaaaac actgcccaga
    24721 tcctctatct cctttacata gccctctttt ccctctttgt catcatctat tatctagccg
    24781 gtatgcctct ctacgatagt tttgtcattg ctatggggac agcgggaact ggaggattta
    24841 ccgtctataa cgatggaatt gcccactatg gtagctcact gattacctat ctggttagta
    24901 taggagtttt ggtttttggg gtaaatttca atctctacta ctaccttatg ctccgtcggg
    24961 ttaaggcctt ctttggtgac gaagaacttc gggcttactt ggtcattgta ctggtttcta
    25021 caggcttgat tagcctcaac accctctacc tctacccagg gttttcaaag agctttgaaa
    25081 tgaccttctt ccaggtttcc aacatcatta caacaactgg ttttggatat ggagatatta
    25141 ccaactggcc cctcttctcc cagtttatcc tccttttcct catggcaatc ggtggctctg
    25201 ctggatcaac tgcaggtgga ctcaagatta ttcgaggcct catcctttca aaaattgcca
    25261 aaaaccagat tttgtcaatc ctatcgcccc accgtgtttt gactctccat gtgaatcaaa
    25321 cggtgattga taaagatacc cagcataaga ttctcaagta ctttgtcatc tatgctatga
    25381 ttttgctagc gcttatcttt attgtcagcc tagatagcaa tgattttctg gtcgtgacca
    25441 gcgctgtctt tagctgtttc aataatatcg ggcctattct aggaaccact tctagtttct
    25501 caatctttag tcccatctca aaaattctcc tatcctttgc aatgattgca gggcgcttgg
    25561 agatttaccc aatcctcctt ctctttatga agagaacttg gtctaagaga taaaatacaa
    25621 aatccctctt tttacaatta tgaaagaggg attcttatat taaaaaaggg ggaacgtttt
    25681 taaatccaag cctatctgta agcaaaatcc ttactcaaat aaaagaggga aaaacttact
    25741 acacagcttg gtaatgctcc aatacaaatt gtaaggattt acttggactc tttgttaaat
    25801 gaatatattc cattcctctg gtagcaacta tctgaatacc taatctttct gcatccacct
    25861 tcatctctct ataataactc cgaacttgtg gagccagaat aattaaatca taaacaccca
    25921 taatatcata atgagctccg tacgctcctg aattcgcaat cactctaact tctgctaatt
    25981 gagtgccctc gttaattgca ttggctaatt gcgcacttgt tccagaccct gcacaaagaa
    26041 ccagtacttt caactcctta ctttttatta catctatctc accaggcatt atttcacttg
    26101 tatcctcctc taaaataata tcatttgagc ttgcaatatc tataacctgt agtaaatatc
    26161 tcatatttag acaatatgaa aacaagacga cttccatata ggaaaccgcc ttctcgctat
    26221 gttgagtgat ttatattaaa ataacttttc ttctagctgc attttattat tataaaaaca
    26281 ttcatcataa cccccagaac ttaaataaca atttttattc aagatacata ctcctagaat
    26341 aaactttata tgaaattctc atttttgttt ttacaattct ccttagttaa atcttgttta
    26401 atatatgttt tacatatagt atttagcgcc acatagtact gaactctctc caaaaacggt
    26461 tattcctctt tgaatagggc gttatcacaa gaaaagcatc tccacgtttc aacttcatat
    26521 ggctcaaaaa caatcaattg atgctaaaac ctgtacctag atgtttcggt tcataaaacc
    26581 atgaaactgt aaaagtggat gaaattgata gcgatagtca aatcaagagg catcataact
    26641 ctaaaaagtc acaatatata agttcatcct cggaaaaata tcattctaat tgttgaaatg
    26701 cctacatgaa aagaaacgtc aaatactcat gaaacaacga atacaggtat caaaactatg
    26761 acaaaacaag tccctaaatt tactaaagac actgctcaac tttacacctg taaatggttg
    26821 ttgtataata aagttacaaa gatgtacgac cacactgttg taaatcatag tgttcgcgaa
    26881 tatattactg atagcatttc tacaaataca attgaaaagg ctggataggc tttaaacgaa
    26941 atatgtcagt gttttggcat tcctagcctt catatcattt aaagaattgt atagacaaaa
    27001 tttttcccaa tacagacact cgtaacaact gcttcatttt tctaccaaca tatttaggaa
    27061 caggataaga tacaagagga ttaatccata gatcagttct ataccaatct aagacaaata
    27121 agctaaaaaa acgattgata ataagcaaat agattccaaa ttttctctat ctgctcattt
    27181 taataaacaa tactagtgta actatccttc cagtcagaag cttgtcaaat cacaccgaaa
    27241 attcttctaa aatttatctc gttaggcaat caagcaaaaa ctcgacgata gtacaaacat
    27301 tatcatacag aattgacttc ctaaattata tactttagta aggttttcgg ataagaaaaa
    27361 aggttcattt tacatttcta aacattcttt tctaagatga aaaacagaat ttttcgattg
    27421 tgatttaaag caacaagaag attttcagta tcatcctata gatacgagct aattaagaaa
    27481 aactacattt ttgaatataa actacaataa tataaactaa attttatagg aggaagacaa
    27541 tggtttggta cgattatatg atacaggcat ccaaacaatc acaattcaac gcaagccatt
    27601 ggtttcgcta tttgcgaaaa gttatttttg aagactattc ttatttaaca aaccaagatg
    27661 tagaaaagtt gctagactcc aaagaactaa cccgttttca aaaaattagc ttgaagtatg
    27721 cctttcaaga gcatactcca actcataaat atgtgatttc attaaataaa cctgctaagt
    27781 taaccaatgt tcaaaaattg atggagaaat acaaacatgg ataaaatgaa accggtcttc
    27841 caagccctaa ataaggaatt aattcaggaa aatctgactt taataattat ctgtgtcgat
    27901 ggttatgtct tagaatatca tggtttacgt gccacacaag atgttgatgc tttttatgac
    27961 caaaatcaga aaatcaatga aattattgct cgtgtaggaa aacagtttaa tcttaacatc
    28021 cacgaagagt tatggctcaa caatcatgtt gcaaagcaaa tatgaacaaa caacctccct
    28081 taagtttatg cgaatccttg tactcatttg agaatctgac cgttttagta gtccctattg
    28141 agtatgtgtt aggaatgaag atgatgagta tcagagagca ggatttgcaa gatattggtg
    28201 caattattaa atacaaaaac tttcattcac cattcgatac ctttaaatat ttaaaagaca
    28261 tgggatttga tactattgac ctctctgttc tattagaagg ttttagttat gcttatggta
    28321 tggattggtt agaaaaattt tttaaagaaa atcaagataa acttcgcgaa ttttattaac
    28381 agtatcaaac aagatgattg tcaattagcc agtcgtcttg ttttttatga tgaaatgaaa
    28441 taaaatctga acaaatcgct tagagaattc cagtcaattt ctagcgctgt ttgagacgtt
    28501 tcagtggact atagtaaaat gaaataagaa taggacaaat cgatcaggac agtcaaatcg
    28561 atttctaaga atgttttaga aataaaggtg tactattcta gtttcaatct attatatttc
    28621 agattcggtc cactattcct tcccaaaaac attgcatatt gcgccgaagg aattgctcac
    28681 actatcccaa gcacaaaacc ctcagtcgtt tgaccgaggg ttccttttca ttattcaaga
    28741 acttgattag ctcaatgcat ccaaggcgtc atccattgaa agaacttcgt ggaagacacg
    28801 ttgtgtcaat tcagtttttt gttctggagt gaggtattta gtgtttacac agtatccaga
    28861 gatacgtacg ataacgtctt cgcctgacat gatcttttcg taaacatcgt tcaagtccat
    28921 aacgttcaag ttaacgtgtt gtccaccgtt ttcgaagtaa ccatcaagga ttgttaccaa
    28981 gttatcaact tgttcatcac gagtcttacc aagagcgcga ggtgatactt gtgtagtcaa
    29041 tgagataccg tcagctgcat aactaaagtc aaggctagaa agtgagttca agttttgcaa
    29101 ccaaccacct ttagctttgt tagatgggtt agcacctggt gagaagaatt caagtttaga
    29161 caagttcaca gaaccatctt cgttgaggta tacacctttg tgaactggtg agttaccagt
    29221 ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt gatactgtag cttctgcgtc
    29281 tttgtatagt ttgtggctac gtagacgagt tgtgtaagct tcgatcaacc attctgccaa
    29341 ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag tcaccgattg tttcgtaatc
    29401 gtagatgtag ccatcttcgt cacggattgg tttaactgta gcgtatttga tagctgacaa
    29461 tgtatcaaca gtgttagcaa atccacagat accgaatccc atgttggcac gttgtttagt
    29521 tggcaagaag gccatttgaa cagcttcgta gttgtaccta tcagtcatgt agtggatgat
    29581 gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga gatttttcaa agttcgcttt
    29641 aactgattca aattcaagaa cttcgtcacg gattggttcg atatcaaata ctttgtagtc
    29701 tttgtgaaca tcgtcgtaac caccattcaa accagtaaga agggctttaa gaacgtttac
    29761 acgagcaccg aagtactgga tgttgtggcg ttgttcttca ttttctggat caagtggaga
    29821 cacacagcat gagatacagc tcatttcacc atatccgtct ttagccattg ttgttacacc
    29881 ttcgtattgg atagaagagt gtttgtggct catgtgcata cagtagcgac ggaagttgta
    29941 tggcaatttg tcagtccaaa gaactgtcaa gtttggttct ggtgagttac cgatgttgtc
    30001 aagagtgttc aagaaacggt agtccatctt agtaacacgg tgacgaccgt cgttacccat
    30061 accagccata gaagttgtga taaaggttgg gtcacctgag tacaattggt cataagcttt
    30121 ggtacgagca aatttaactg tacgaagttt cataacgaaa tcatcaacga attcttggat
    30181 ttctgattca gtaaatgtac cacgagcaag gtcacgttct gcaaagatgt ccaatacgat
    30241 tggtacacga cctagagatg tagcagcacc gttaatcaca cggcagacag ccatgaaagc
    30301 aatgttaacc cattggattg cttctttcac gttcatcgct ggtttgcgaa catcaacccc
    30361 gtaaaggtca cccaggcgaa caacttgttg caatgcttgg tattgaaggt ttacttcttc
    30421 acgaagacgg attgtttctt catcgatttc tttgattgca ttccagtcgt ttactttttc
    30481 ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg taaacaccga tgatacgtcc
    30541 gcgtgagtat gcatctggaa gaccagttac agtgtgtgca tgacgagcgc gacgaatatt
    30601 tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt acatatttag tgaagatttc
    30661 gtgaacagct gggtctggtt cgtatccatt ttcttttaaa gtagtttcag ccatacggat
    30721 accacctttt ggcatgaagt tcaatttgaa gagttcatca ttttggatac caaagataac
    30781 ttcattttct ttgtcgataa atccagcagg gatatcagcg atagatgttg gacgagtgtc
    30841 cattgggaaa cgagtttctt cgtagtgtgc tttagtttct tctacaattt tcttgatgtg
    30901 aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct ccatcataag gtgtgtagtt
    30961 agcttgtaca aagcgtgata cacttgcttt ttctttccaa tctacgcctt tgaagccttc
    31021 ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc ttaacaacca tattaatgtc
    31081 ctcttttttc tagtaacagt catctgttac attcataaga caagtatacc ataaagtaac
    31141 cgatttcaac aagtgcaaaa tccctatttt tacactttct tttctaaaac agtctatatt
    31201 ttatttcaaa ctgtattata tttttgaaaa aaataaagtc cttttttctt tttttcagaa
    31261 aaaagggtat aataaaagaa aataagcagt aacactcaat ggaaatcgaa
//
LOCUS       DAVDFK010000021        31209 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.21, whole genome shotgun sequence.
ACCESSION   DAVDFK010000021 DAVDFK010000000
VERSION     DAVDFK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.21"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            24..735
                     /locus_tag="VUR04_001232"
                     /pseudo
     CDS             24..735
                     /locus_tag="VUR04_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            747..1496
                     /locus_tag="VUR04_001233"
     CDS             747..1496
                     /locus_tag="VUR04_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET5341129.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            1509..2680
                     /locus_tag="VUR04_001234"
                     /pseudo
     CDS             1509..2680
                     /locus_tag="VUR04_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            3075..3938
                     /locus_tag="VUR04_001235"
     CDS             3075..3938
                     /locus_tag="VUR04_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET5341130.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYVPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            4404..6917
                     /locus_tag="VUR04_001236"
     CDS             4404..6917
                     /locus_tag="VUR04_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET5341131.1"
                     /translation="MDRLQTMLNKIQVDTYHKNGWLFVKYSNNKLTQGWKLHVSSQLK
                     DACNIFYIVAQELEKERCNYKVLDCLDELKKLNSPREVSPTANKFITIYPSSRKQAKR
                     IILNLKEKLEKYKAPRILSDFQCGEYSPIHYRYGAFKAIKNYNFSENKIVYMMKNSRG
                     ELVEDLRLSYPYLPEGVKDLFTDMEKNKLFKPSPEIPENHPLNHYNIECILKKSNRGN
                     VYRAIEKSSNQKVIIKHARPYVYSWNDGFSAIDELKSEAANLKVFQDKSYTTDLIEEF
                     YVNEDYFVVQKFIPGYNFFDLKNIDIEKNVIINNIIDIINDIHAEGYLAVDISPTNFI
                     LDDFGRVRLIDLENFTNKNNTVRRAATKFMINTDCPSKICTIQQDYFALAMLSFAIMR
                     EHVLIFEGEDVLLNITALDKIKFCMYSEKEIGNITKSQFNWLMYLLNLSEQEKLDRFE
                     KMKYINDFEDKNIEFHLKKVDSSFNLQIENETLINYLLSLNMNRESRILNSNEFGEFV
                     SPISFQHGLSGYLFYLSHMRDISENGRIIEWIISEGNQNKGNVYLNGCSILFGSSGYL
                     WVLLEFYKKITSNNPSRELIIDKIRDIYKDLISSYQKVEVFDFALGKSGILLSLMKYC
                     INFNDVDSMEFIREKIEELYLYFVDEIRNVNSLKECNFAHGLAGIAYVILIYNSEFEF
                     KVAYENSIKVFNNLLENLLENEYSRLNATPTNLELSWCEGTSGILLYFELLYDKRYSN
                     IISRFQQLAFKFNLIQSSCYCHGLSSLLQTLNYQDKLNLRENVIEILLSRSKRDKNGI
                     LVFECEESSDTLFDFGIGNLGIYWSILGERFPFELKKEL"
     gene            6917..8143
                     /locus_tag="VUR04_001237"
     CDS             6917..8143
                     /locus_tag="VUR04_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5341132.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            8591..9247
                     /locus_tag="VUR04_001238"
     CDS             8591..9247
                     /locus_tag="VUR04_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET5341133.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSIWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            9237..9560
                     /locus_tag="VUR04_001239"
     CDS             9237..9560
                     /locus_tag="VUR04_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET5341134.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            9664..10494
                     /locus_tag="VUR04_001240"
     CDS             9664..10494
                     /locus_tag="VUR04_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5341135.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            10648..11502
                     /locus_tag="VUR04_001241"
     CDS             10648..11502
                     /locus_tag="VUR04_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET5341136.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            11602..12975
                     /locus_tag="VUR04_001242"
     CDS             11602..12975
                     /locus_tag="VUR04_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET5341137.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESCTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            12968..14029
                     /locus_tag="VUR04_001243"
     CDS             12968..14029
                     /locus_tag="VUR04_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET5341138.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            14031..14723
                     /locus_tag="VUR04_001244"
     CDS             14031..14723
                     /locus_tag="VUR04_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341139.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVCVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(14753..15322)
                     /locus_tag="VUR04_001245"
     CDS             complement(14753..15322)
                     /locus_tag="VUR04_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET5341140.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPRTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            15457..16071
                     /locus_tag="VUR04_001246"
     CDS             15457..16071
                     /locus_tag="VUR04_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET5341141.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVTKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            16073..17719
                     /locus_tag="VUR04_001247"
     CDS             16073..17719
                     /locus_tag="VUR04_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5341142.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            17731..19017
                     /locus_tag="VUR04_001248"
     CDS             17731..19017
                     /locus_tag="VUR04_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341143.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATVSHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            19078..19611
                     /locus_tag="VUR04_001249"
     CDS             19078..19611
                     /locus_tag="VUR04_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341144.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            19689..20159
                     /gene="nrdI"
                     /locus_tag="VUR04_001250"
     CDS             19689..20159
                     /gene="nrdI"
                     /locus_tag="VUR04_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET5341145.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(20452..21714)
                     /locus_tag="VUR04_001251"
     CDS             complement(20452..21714)
                     /locus_tag="VUR04_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET5341146.1"
                     /translation="MSQAITLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(22024..22482)
                     /locus_tag="VUR04_001252"
     CDS             complement(22024..22482)
                     /locus_tag="VUR04_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET5341147.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(22479..22919)
                     /locus_tag="VUR04_001253"
     CDS             complement(22479..22919)
                     /locus_tag="VUR04_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341148.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            23275..25224
                     /gene="mutL"
                     /locus_tag="VUR04_001254"
     CDS             23275..25224
                     /gene="mutL"
                     /locus_tag="VUR04_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET5341149.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMALVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(25549..26016)
                     /locus_tag="VUR04_001255"
     CDS             complement(25549..26016)
                     /locus_tag="VUR04_001255"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET5341150.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(26017..27222)
                     /locus_tag="VUR04_001256"
     CDS             complement(26017..27222)
                     /locus_tag="VUR04_001256"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET5341151.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(27242..27877)
                     /gene="ribE"
                     /locus_tag="VUR04_001257"
     CDS             complement(27242..27877)
                     /gene="ribE"
                     /locus_tag="VUR04_001257"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET5341152.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGNTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(27862..28962)
                     /gene="ribD"
                     /locus_tag="VUR04_001258"
     CDS             complement(27862..28962)
                     /gene="ribD"
                     /locus_tag="VUR04_001258"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET5341153.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCLQE"
     regulatory      complement(29096..29210)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            29367..29960
                     /gene="ruvA"
                     /locus_tag="VUR04_001259"
     CDS             29367..29960
                     /gene="ruvA"
                     /locus_tag="VUR04_001259"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET5341154.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            29970..30533
                     /locus_tag="VUR04_001260"
     CDS             29970..30533
                     /locus_tag="VUR04_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET5341155.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            30530..31207
                     /locus_tag="VUR04_001261"
     CDS             30530..31207
                     /locus_tag="VUR04_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5341156.1"
                     /translation="MMSNKNKEILIFAILYTVLFVFDGVKLLASLMPYVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSFALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
BASE COUNT         9453 a         5521 c         6439 g         9796 t
ORIGIN      
        1 attttcccga tatagtatgg agattggaag gaagtctctt tgaatgtggt gtcatactgc
       61 agtactattt aggcaggttg ttgttccaaa aagggaacac aagtattctt tgtggcgagt
      121 cagcggatga aataatgact tttaagtatc attctgtgaa ctacaatcaa ttttgtaatg
      181 ataaacagaa gtcagtatat tttagttatt ccgactatcc attttatgtt acaaattcaa
      241 ttgttttaaa gaaaaatagc ctacttttgc atagttttgg cattcatcct agatatccat
      301 ataaaatgtc tgagattgtt gaaatgtcta aaaaaatatc agatttaaac gataaaaaag
      361 aatttcacaa aaagaactgt gagttgaggt ttcaagatag tgttcttgat aacataaata
      421 gtgtcccggg tacaactcat ttatttagtt gtttaaatat tcaaacatta gtaaaaatta
      481 ttttatatat ttttcgatac aacagttgta tcgaaaatat ttaattttag agataaagag
      541 cttatctttt ttaataagat tgtaaatggg ctgatacaaa atattgagga gaatttagag
      601 gatgatattg aaaggatatt gaaatattta tatatatgtt tatttaacga aatattcatt
      661 attaagaata aggtgaattt ttttgatgat gtggaattta atcagacact tagtgagttt
      721 ttagataaat tgtagaggga atggttatga gtaacaatac taagtatatc tttttatctc
      781 cacatttaga tgacgcaatt ttttcctgta gtgattatat ttcaaaatta acttcagaag
      841 gagaaattgt acttgttatt actatatttt ctggttaccc tttgagccaa cagctacagc
      901 cctctgctaa gcaatttcat aagttgtgta accttgggaa atatccgatt gaagaaagga
      961 agaaagaaga caggttagct tgtgaacgtc tacaatgtga ttttagacac ttatcgtact
     1021 atgaatgtct ctataggaaa gatagaaatg gcaattttct ataccgtcat atctatagtg
     1081 aattaaaaaa tgaggacaca ttaaagaatg atatcataaa agagctgtta atgcatttag
     1141 acgataaatg tgtcgtatat tgtccgcttt cacttggtga ccatgttgat catgtttttg
     1201 tgaatagtat tggaagggcg cttgaattta tgcgttataa agtaatatat tatgaggatt
     1261 tcccatatgt aagtgatagt agtatggtta gttatatggg aaaaactaaa gaattaaaaa
     1321 tgtatcaaga ggaacttgat gaaaaacatt atattgatag aatatcatca atattgtgct
     1381 ataaatctca gattttgata atctggaaat cagttgaaaa acttttaaac aatattaaag
     1441 agttgtattt aaggaatggg gcagcttatt ctattatatt ttggattaag aaataaggaa
     1501 gtagttttat gaatatagca gtaattggtt tggggcatgt tgggctggcc tacgcgttac
     1561 tatttgcatc taaatataaa gttgttgcat atgatataga ttctgtaaaa ataaataatt
     1621 taaaaaaggg cattcttcca tctaaaaatg aagagcttat gaagtttttt tgcgagaata
     1681 acttaaatat tacttttttt gatacatttt ctgaaattaa aaataatatt gattattata
     1741 ttattgcgct tccgacagat tatgatgaga aaattggtag ttttaataca tatgaaatcg
     1801 aacaaacggt atcgaagatt ctgagggtaa aacctaatgg aaagattatt ttaaagtcaa
     1861 cagttccgat cggcttttca aacaaattaa aaaggctgtt tgatacaaaa aatatcattt
     1921 ttgtccctga atttttgaga gaaggttgtt ctatatatga taatttatat ccaagtcgca
     1981 tagttgttgg agatgagaca gttgaaggaa gaaaaattgc agagttgttc ctttcgatta
     2041 gtactcatag tactgccaat attaaaaatg ttatgttagt ttctcctact gaagcagaag
     2101 caattaagct tttttctaac acattcttag ctctccgtgt tgctttttta atgaactaga
     2161 ttcttttgct gagaggagaa gtttaaatgc tgaagttgta ataaaaggtg tttgtttaga
     2221 tccaagaatt ggaaattttt ataataatcc ttcttttgga tttggaggat attgtcttcc
     2281 caaagatact aaacaattaa aaaaagaatt tatagaaata aatgccccag tgatagaagc
     2341 gattgatatt tcaaacacaa atagaaaaca gttcatagtt aaacaaatat tggaacgaaa
     2401 gccaaagata gtaggaatat ataaattggg gatgaaatat aattcagata attacaaaga
     2461 gtcagctatt ttaagtataa ttaatgaact attgattgtc ggtataaaaa ttttagtata
     2521 tgaaccaaat ttaaacgtta gtatagataa cgtaattttt gaaaagaatt ttgaactatt
     2581 tacaaaacaa agtgatctaa ttgttgcaaa tagatgggat aggggccttg aagcttataa
     2641 agataaagtt tacacaaggg ggatctggat aagagattaa ctattgatat taaaaaggca
     2701 ataatttata aaatttgtac aaaaaaatgt taaattttca cattttcata gtatactgtt
     2761 taatagaaag taggttcttt gtaaccgctc cattataaaa tcctttcact cttccggtat
     2821 actattagga aaaacataac tggaggatat tttgagctca cacctcatcg ttccagtggc
     2881 tgttccccaa gctcgtgtac tgcccaaaaa agttagacat tctatttaga acgaggattg
     2941 agttctgtat tgtacaaggc tcggtccttt tagagtcagc ttaaggctgg cttttttgcc
     3001 ctcttaaata tcagaatatt ttgacaaatg attgtaaata atgatataat atgcaaaagc
     3061 taggaggtgg tcagatgatt gagagaatgg aattgggaga attttacaag gaattgcgct
     3121 tggcgagaaa acttaagcag tcagatgtgg cctgtgaggg tctaacagct tctcagttgt
     3181 ccaagtttga actaggacag tctatgttat ctgcagataa gctcatatta gccatccaag
     3241 ggatcaatat gaattttgat gagtttgggc acaagctcaa caactatcaa gaatctccac
     3301 atatgcgaat cggtcgaaag gttgtggatc gctttgccca tcaggatata gctgctttag
     3361 agcagctatt ggaggaagtc gatcaagaac agatggcgca gacctatcgt cgtttgaatg
     3421 ccattgtgat taaaaatgca ctccattcct tagataaaag ctacccgcta acagaggagg
     3481 atagcgagtt tttgactacc tacctctacg ctattgagtc ttggacctgg tttgaactct
     3541 atcttttttg caatactatg cccttcttga gcaatcaaga tctgatcttt ttatcaacct
     3601 ccttactcga aaaatccaag gaatttaaag agttagtaca caatcgatgg tatatgaaaa
     3661 gtggttatct taatatcatc tcagaactta tggagcgcaa gctattttct tatgttccaa
     3721 tctttgaagc tgagctggag cgcatgctcc gtccatacga tgtttttgaa aaagtattgt
     3781 ggcagttttt aaagaaaatg cagatttttc ttcaaaccaa aggaagcaat caaaaagaga
     3841 ttgaacactt tatccaatct ctgcaagtat tagaaaatcc acaattgaca gccctttttg
     3901 aattgcgttt gcagcaatac aaagagctta tcgattagtt agaaatggga aaaagataat
     3961 aatatcagca acgatcgtca ataatgttaa aacttgtttc ttcatattac ttccctcctc
     4021 attagtaata actttattat accagggaaa taatcaaatc taccaaaatc gcaaatctga
     4081 aatttctata agaaaaaata tcaaatatgc gattttctaa aataagccaa tttccgtgtt
     4141 atactgtcct tgtaaaacat ttgaagcaaa tcctaggtcg cagaagtggt ttacaaaaaa
     4201 ataatcaaag gagaaaagaa atgcataatc taatggaact tgaattgtta cctgaagagc
     4261 cagtaattac tgtatcacgg gaagtttgta agtggacttg ctcatttact gctctttaag
     4321 aataactggt taaaattaag gatagttgat tactaattaa ctatccttaa tttcatttca
     4381 gagataatgt atttattata tttatggata gattacaaac aatgctgaat aaaatacaag
     4441 ttgatactta ccataaaaat ggatggttat ttgtgaagta tagtaacaat aaacttacac
     4501 agggatggaa acttcatgta agcagtcaac taaaagacgc ttgtaatatt ttttatattg
     4561 ttgcacaaga gctggaaaag gaaagatgta actacaaagt tctagattgt ttggatgagt
     4621 taaaaaaatt aaattctcct agggaagttt ctcctactgc aaataagttt atcactatat
     4681 atccgtctag taggaagcag gccaaacgaa taatattaaa tctaaaagaa aagttagaaa
     4741 aatataaagc tccaaggatt ttatcagatt ttcaatgtgg tgagtattct ccaatacatt
     4801 atagatatgg tgcgtttaaa gcaattaaaa attacaattt ttctgaaaat aaaattgtct
     4861 acatgatgaa aaatagtaga ggagaattag tagaagatct gagattaagt tatccatatt
     4921 tgccagaagg ggttaaggat ttatttactg atatggaaaa aaataaatta tttaaaccct
     4981 ccccggaaat cccagagaat caccctttaa atcactataa tatcgagtgt attctaaaaa
     5041 aatccaatag aggaaatgtt tacagagcta tagaaaaaag tagtaatcag aaagtgataa
     5101 taaaacacgc acggccatat gtttatagtt ggaatgatgg tttctctgca attgatgaat
     5161 taaagagtga agcagcaaat ttaaaagtat ttcaggataa gtcctataca acagatttaa
     5221 ttgaagagtt ttatgtcaat gaagattact tcgtagtaca gaagtttata ccaggatata
     5281 atttttttga tttaaaaaat attgatatcg aaaaaaatgt aatcattaat aatataattg
     5341 atattattaa tgatattcat gctgagggat atttagcagt ggatatttct ccaacaaact
     5401 ttatattgga tgattttggt cgtgttaggt taatagactt agaaaatttt acaaacaaaa
     5461 acaatactgt tagaagagct gctacaaaat tcatgataaa tactgattgt ccctcaaaaa
     5521 tctgtaccat tcaacaggat tattttgcac ttgcaatgtt gagttttgct attatgcgcg
     5581 agcatgtttt aatatttgaa ggagaggacg tcttattaaa tataactgct ttagataaaa
     5641 tcaagttttg tatgtatagc gagaaagaaa ttgggaacat aactaaatcg caatttaatt
     5701 ggttgatgta tttattgaat ttaagtgaac aagagaagtt agaccgattc gagaagatga
     5761 agtatataaa cgattttgaa gataaaaata tagaatttca tttaaagaaa gttgattcct
     5821 cattcaatct tcaaattgaa aatgaaacgc ttattaacta tcttctttcg ttaaatatga
     5881 atagagaaag caggatacta aattcaaatg aatttggaga atttgttagt ccaatatcgt
     5941 ttcaacatgg cttatcagga tatttgtttt atttatcaca tatgagagac atttctgaga
     6001 atggtagaat tatcgagtgg attatctctg aaggaaatca aaataaagga aatgtgtatc
     6061 taaatggttg ttcaatttta tttggttctt ccggatatct ttgggtatta ttagagttct
     6121 ataaaaaaat taccagcaac aatccaagta gagaattgat catagataaa attagagata
     6181 tttataaaga cttgataagt agttatcaaa aagttgaagt atttgacttt gctttaggaa
     6241 agtcaggtat tttattgagt cttatgaaat actgtataaa tttcaatgat gtcgatagta
     6301 tggaatttat tagagaaaaa atagaggagt tatatttata ttttgtagat gagatacgaa
     6361 atgttaatag tttaaaagaa tgtaattttg cacatggtct agctggaatt gcatacgtaa
     6421 ttttaattta taattcggaa tttgaattca aggtagctta cgaaaatagt attaaggtat
     6481 tcaataatct gttagaaaat ttgttagaaa atgaatatag tagactaaat gcaactccta
     6541 caaatttaga actatcgtgg tgcgaaggaa cttcaggaat cttactttat tttgagttat
     6601 tatatgacaa aaggtattca aacataattt caaggtttca acaacttgct ttcaaattca
     6661 atcttatcca gtcaagttgt tattgtcatg gcttatccag tttgttgcaa actctaaact
     6721 atcaggataa attaaattta cgtgagaatg tgattgagat tttattaagt agatccaaaa
     6781 gagataaaaa tggtattttg gtatttgaat gtgaagaaag ttcagataca ttatttgatt
     6841 ttggtatcgg aaatctaggg atttattggt ctatccttgg ggaaagattc ccatttgaac
     6901 ttaagaagga gttgtgatga aagtatttct tcaaaataga gattttaggc aattaactat
     6961 caaccagtgg atttcaacgc ttggggatac gattttttat ctggccttcc tgaattatgt
     7021 ggcagatgca tcttttgccc ctttggcgat tttactcatc acgatttcag aaaccctgcc
     7081 ccaagttcta caaatctttc tgggagtttt ggcggatttt caacatcatc gtgtcttgaa
     7141 atacacagtc attagttttg caaaattttt gctttactct atagtgtctt tatcactttc
     7201 agggcagtcc ttttccttgt tattagtagc atttatttgt ctgattaacc tcttgtctga
     7261 cacgttgagt tatttttcag gcgccatgct cactccgatt ttcattagaa ttattgggca
     7321 agaccatctg gcagaagcta ttggatttaa acagtcaact gttagtttag tgaaaacaat
     7381 cagtaatatt ctaggaggag tcttattagg tattctatcc atccagttta tttccttgct
     7441 gaacgctctt acctttttaa tcgcattttt aggtatcctc ttcataaaaa ctgacctctt
     7501 gaaagtagaa aaaacgatta actatcaaga aggactctct gtaaaatcct tttgccagca
     7561 tttgctccaa tcatcgaaat tgatatggaa tatgaataag gtgctcttgg ttttgtttat
     7621 tatctctact agtcaagcag tgataaatgt tacagttcct gtctctactc tatttttgag
     7681 gaatcaaccc tttttgaatt tacaaacagg tcaatctctt gccttgctat ccacttttga
     7741 actgtcagcc ctgattgtcg gaagccttgt aagtggctat ctgcaacata ccatttccat
     7801 aaaaacagct ctctatgcct cacttgtcac ccagttgctt cttctagtag gatttgccac
     7861 agttcgtttt gactggattc tcatctttag taccttggat gcctttttcg caggtgttct
     7921 ctctcctaga ttgcaagaac tcgtttttaa acaaatacct gaggagtcaa tgggagcagt
     7981 tcaatcctct atcggtgcca ttacggttgt tttacctagc ttatttacaa tagctttggt
     8041 aaccattgct actagctttg gaactctggc agttagcttt gttttattgc tatttcttct
     8101 agttgccttt gttatgcttc tgaatattcg tgaaagtatt tagtggagaa tttctataat
     8161 atatgtttga gactggattg ccagcctttt tatgatggtc aaaatcaaca gacttttttc
     8221 tcttttctga atgtgttata atagactgaa tctaaaatag tacgaaacaa ttgctaaaac
     8281 atttatttat agaaattaat tttactttcc caatcgattt gttctcatct tatttcaatc
     8341 tgctatataa tagtccatgc tgtggctgga ttcttttcag cctacttata ctcttcgaaa
     8401 ctctcttcaa accacgtcag cttcaccttg ccgtaggtat ggttactgac ttcgtcagtt
     8461 ctatccacaa cctcaaaaca gtgttttgag ctgactacgt cagttctatc tgcttttcat
     8521 tgagtactat taagacaata tgaggagaaa gatgaaagaa aaaggatttt aggagggggc
     8581 gcaggcagcc atgccaacgg ctcttggcta tgtcagtatc ggcctggcct gtgggactat
     8641 cggtgcgccc tatgtgacac ctgttgagat gggcttgatg agtctctttg tttatgctgg
     8701 gagtgcccag tttgccatgt tggcactgat tgtggttcaa gctcctgtgg cagctattgc
     8761 tatgacggtt tttctaatca acttgcgtct ctttttgttg agtttacacg catcgactta
     8821 tttccgtcat accagtattt ggtacaatat cggtatgtct agtatcttga cagatgagac
     8881 ctatggcgtt ttgatgggtg aattggccca tacagacaag gtaaatccta tgtggatgca
     8941 cggaaacaat cttaacagct atgtggcttg gtttgtgggg acagtagtcg gaacggctct
     9001 gggtggcctg ctaccaaatc cagaaatctt tggcttggat tttgccctgg ttgggatgtt
     9061 tattggtatt tttgcttcgc aatttcagat tatgcaaaga cggattcctg tccgcaatct
     9121 gctcattatc ctagcagttg ttgcggtgtc cttctttttg ctcttgacag tggtgtctca
     9181 gtcactagct gttctgtttg cgacgctact tggttgtagc atgggggtgg ttttagatgg
     9241 tcagtaagta tcttttatta gcagttattt tctctggctt ggtgacttgg attctccgta
     9301 tgattccctt catcttagtc aagtataagg gcttgcctgc aatcgttgag cgttttttga
     9361 agttcttgcc cgtttccatt atctttgcct tgattctttc aagcgtagtg acaggtaagg
     9421 ttgggagcct tcctcaaatt aaatggctag acttcttagc cgtctttcca acagcttggg
     9481 tagcctttcg ctaccgcaat ctagtcggaa cagttctctt tggagtggtc ttgattgcca
     9541 tcttgcgttt ggtcttttaa attacccata aaaaaaactt atcacagaga tagatatcat
     9601 ataatggcgt aaatgctctt tttctgttaa gattataagg tattctattt tggaggaaat
     9661 gacatgaaaa aaatcgttaa atactcatct cttgctgccc taggacttgt tgctgcaggt
     9721 gtgcttgcgg cttgctcagg gggtgctaag aaagaaggag aagcagctag caagaaagaa
     9781 atcatcgttg caaccaatgg atcaccaagg ccatttatct atgaagaaaa tggcgaattg
     9841 actggttacg agattgaagt cgttcgcgct atctttaaag attctgacaa atatgatgtc
     9901 aagtttgaaa agacagaatg gtcaggtgtc tttgctggtc ttgacgctga ccgttacaat
     9961 atggctgtca acaatcttag ctacactaaa gaacgtgcgg agaaatacct ctatgccgca
    10021 ccaattgccc aaaatcctaa tgtccttgtc gtgaagaaag atgactctag tatcaagtct
    10081 ctcgatgata tcggtggaaa atcgacggaa gtcgttcaag ccactacatc agctaagcag
    10141 ttagaagcat acaatgctga acacacggac aacccaacta tccttaacta tactaaggca
    10201 gacttccaac aaatcatggt acgtttgagc gatggacaat ttgactacaa gatttttgat
    10261 aaaatcggtg ttgaaacagt gatcaagaac caaggtttgg acaacttgaa agttatcgaa
    10321 cttccaagcg accaacaacc gtacgtttac ccacttcttg ctcaaggtca agatgagttg
    10381 aaatcatttg tagacaaacg catcaaagaa ctttataaag atggaactct tgaaaaattg
    10441 tctaaacaat tcttcggaga cacttatcta ccggcagaag ctgatattaa ataatttctt
    10501 gaaatcatcc attctgagta aggtgggtgg tttctcagtt tttagggata tagttttaaa
    10561 ctatatatct gactatctaa taacaatttg tgaaatcaaa caaattgtga gatactagta
    10621 cggtattatt tttaaggaga aagaatcatg aaaatcaaaa aatggcttgg cctagcagcc
    10681 cttgctacag tcgcaggttt ggctcttgca gcttgcggaa actcagaaaa gaaagcagac
    10741 aatgcaacaa ctatcaaaat cgcaactgtt aaccgtagcg gttctgaaga aaaacgttgg
    10801 gacaaaatcc aagaattggt taaaaaagac ggaattacct tggaatttac agagttcaca
    10861 gactattcac aaccaaacaa agcaactgct gatggcgaag tagatttgaa cgctttccaa
    10921 cactataact tcttgaacaa ctggaacaaa gaaaacggaa aagaccttgt agcgattgga
    10981 gatacttaca tctctccaat tcgcctttac tcaggtttga atggaagtgc caacaagtac
    11041 actaaagtag aagacatccc agcaaacgga gaaatcgctg taccgaatga cgctacaaac
    11101 gaaagccgtg cgctttactt gcttcaatca gctggcttga ttaaattgga tgtttctgga
    11161 actgctcttg caacagttgc caacatcaaa gaaaatccaa agaacttgaa aatcactgaa
    11221 ttggacgcta gccaaacagc tcgttcattg tcatcagttg acgctgccgt tgtaaacaat
    11281 accttcgtta cagaagcaaa attggactac aagaaagcac ttttcaaaga acaagctgat
    11341 gaaaactcaa aacaatggta caacatcatt gttgcgaaaa aagattggga aacatcacct
    11401 aaggctgatg ctatcaagaa agtaatcgca gcttaccaca cagatgacgt gaaaaaagtt
    11461 atcgaagaaa catcagacgg tttggatcaa ccagtttggt aataagaaac agggaggtgg
    11521 gagagaaaat tccacctctt gcttttgtat agagtataga ttgtaaagaa gactattcgt
    11581 tcatagaaag gtagagagaa tatggttttt cctagcgaac aagaacagat tgaaaaattt
    11641 gaaaaggatc atgtagtcca acattatttt gaggttttgc gtaccttgat ttctaagaaa
    11701 tcagtctttg cccagcaggt tggactcaag gaagtcgcaa attatctggg tgagattttc
    11761 aagcgtgttg gagctgaagt ggagattgat gagagctgta cagcgccctt tgtcatggca
    11821 catttcaaga gttcgcgtcc agatgccaag accttgattt tctataacca ctatgacact
    11881 gtgccagcgg atggggatca ggtctggaca gaggatcctt ttacgctttc ggtccgcaat
    11941 ggcttcatgt atgggcgtgg ggttgatgac gacaagggtc atatcacagc tcgcttgagt
    12001 gctttgagaa aatatatgca gcaccatgat gatttacctg tcaatatcag ctttatcatg
    12061 gagggagcgg aggaatcggc ttcaacagac ctagataagt atttggaaaa gcatgcagac
    12121 aaactccgtg gggcggattt gttggtctgg gaacaaggga ccaaaaatgc cttggaacag
    12181 ctggaaattt ctggtggcaa taaggggatt gtgacctttg atgccaaggt aaaaagcgct
    12241 gatgtggata tccactcgag ttatggtggt gttgtggaat cagctccttg gtatctcctc
    12301 caagccttac agtctcttcg tgctgcggat ggccgtatct tggttgaagg cttgtacgaa
    12361 gaagtacaag agcccaatga acgagaaatg gccttgctag aaacttatgg tcaacgaaac
    12421 ccagaggaag ttagtcggat ttatggattg gagttgcctc tcttacagga ggatcggatg
    12481 gcctttctaa aacgtttctt tttcgagcca gcgcttaata tcgaaggaat ccagtctggt
    12541 tatcaaggtc agggtgttaa gactatttta cctgcagaag ccagtgccaa gctagaggtt
    12601 cgtctggttc cgggcctaga accgcatgat gttctggaaa aaattcggaa acagctagac
    12661 aaaaatggct ttgataaggt agaattatac tataccttgg gagagatgag ctatcgaagc
    12721 gatatgagcg caccagccat tctcaatgtg atcgagttgg ccaagaaatt ctatccacag
    12781 ggcgtttcag tcttgccgac gacagcgggg acaggaccta tgcatacggt ctttgatgcc
    12841 ctagaggtac caatggttgc attcggtcta ggaaatgcca atagccgaga ccacggtgga
    12901 gatgaaaatg tgcgaatcgc tgattattac acccatatcg aattagtaga ggagctgatt
    12961 agaagctatg agtagagata ttatcaagtt agatcagatc gatgtgactt ttcaccaaaa
    13021 gaagagaacc atcacagcgg ttaaggatgt gaccattcac atccaagaag gggatatcta
    13081 cggaatcgtt ggatattctg gagcagggaa atcaaccctt gtacgggtga ttaatctctt
    13141 gcaaaaacca tctgcaggga aaattaccat tgacgacgat gtgatttttg atggtaaggt
    13201 caccttgacg gcagagcagt tgcgtcgtaa acgtcaagat atcgggatga ttttccagca
    13261 ttttaacctg atgagccaaa agacagcaga ggagaatgta gcctttgccc ttaaacactc
    13321 tggactcagc aaggaagaaa agaaggctaa agtagctaag ttgttggact tggttggttt
    13381 ggcagatcgt gctgaaaact acccttcaca actatctgga gggcaaaaac agcgtgtggc
    13441 aattgcgcgt gccttggcca atgatccaaa aatcttgatt tcagacgagt caacttctgc
    13501 ccttgaccct aagacaacca agcagatttt ggccttgttg caagatttga accaaaaatt
    13561 aggattgaca gttgtcttga ttacgcatga aatgcagatt gtcaaagaca ttgccaaccg
    13621 tgtggcggtt atgcaggatg ggcatttgat tgaagagggg agtgtccttg aaatcttctc
    13681 aaaccctaaa caacctttga ctcaagactt tatctcaaca gccacaggta ttgacgaagc
    13741 catggtcaaa atcgagaagc aagaaatcgt ggaacacttg tctgaaaaca gtctcttggt
    13801 gcaactcaag tacgctggag cttcaacaga cgagccactt ttgaatgaat tgtacaagca
    13861 ttaccaagta atggctaata ttctctatgg gaatatcgaa atcctcgatg gtactcctgt
    13921 tggagaattg gtggtggtct tgtcaggtga aaaagcagcg ttggcaggtg cccaagaagc
    13981 cattcgtcaa gcaggtgtac aactaaaagt attgaaggga gtacagtaag atggaatcat
    14041 tgattcaaac ctatttacca aatgtctata aaatgggttg ggctggtcag gcaggctggg
    14101 gaacggctat ctacttaact ctttatatga cagttctttc cttcattatc ggaggcttct
    14161 tggggctagt ggcaggtctc tttctcgtct tgacagcgcc aggtggtgtc ttggagaata
    14221 aagtcgtatt ctggatttta gacaaaatta cctcaatttt tcgtgcggtt ccctttatca
    14281 tcctcttggc aatcttgtca ccactttctc acttgattgt taaaacaagt atcgggccaa
    14341 atgcagccct tgtcccactt tcttttgcag tctttgcctt ctttgcccgt caggtgcagg
    14401 ttgtcttggc tgaattggat ggcggtgtca ttgaggcggc tcaagcgagc ggagcgactt
    14461 tctgggacat cgtgtgtgtt tacctatcag aaggtcttcc agatttgatc cgtgtgacga
    14521 ctgtgacctt gatttccctt gttggggaaa cagctatggc aggtgcggtt ggagctggtg
    14581 gtatcggtaa cgtagccatc gcttatggat ttaaccgcta caatcacgat gtgaccatct
    14641 tggcaaccat cgttatcatt ttgattatct ttgcaatcca attcttagga gatttcttga
    14701 ctaagaaatt gagccataaa taaaaaagag ccgtgtggct ctttttaact gatcagattt
    14761 tctgggcaaa ttttttactc aaggcttgtc caatcaaggc acccactagg gctccgatga
    14821 caatacttgc gataaataga aggacagttc tagggtttgg agtgaccatg atacggtcga
    14881 tatattcttg ggattttcct cttgccagaa gagtagccat ataggctttg ggcgcaatcc
    14941 acataagcaa gattggtcct gttgtactaa aggcgaaaat aatgaaagaa aggaagttct
    15001 ttgttttgtc cttgtatttt cctaaatgag ctacttcatc tgctaggagg ccacagataa
    15061 ttccaggaag gaaggaacca gcaccgtgtt tagttcccaa gaaaaagagg gcaatgacaa
    15121 ggccgatagt ggtaatggct ccaaagcgcg gaacttttgc gactaggatc atatagacgc
    15181 taccgccgac aagggcagta aaggcaggcg cataaaacat gtttccagtt tggtcaaaga
    15241 gattgcccaa aaggacacca atccccatgc agaggaagta aagaactgca aaaagcagtg
    15301 tagttaagat agatttcttc atgaattgtc tcctgataat tttttcacaa ttctcattgt
    15361 accacggttt ggtgggattg taaatggata ctagaagttt ttgaaaacgc ttgaaatatg
    15421 atataatggt ttcatagtta tttttagggg aatatcatgg gtagattttt agactttgtc
    15481 tttaatcgtt tctttttagg gatgattgcg acagccttct tttggctatt aactttagca
    15541 ggagggatta tccttggtct agcgccggct agtgccacct tgatgagctt atatgcagaa
    15601 catggttata gctttcggga atacagtttg aaggaggctt ggtctcttta caagcaaaat
    15661 tttgtctcaa gcaacctgat tttctatagc tttttaggtg tgggtctagt tttgacctat
    15721 ggtttgtatc tcttggtgca attgcctcat cagaccattg ttcatttgat tgcgaccctt
    15781 ttgaatgtcc tagtagttgc cctgatcttt ttggcttata cagtatcttt aaaattacaa
    15841 gtttattttg ccttgtccta tcgaaatagt ctcaaattat ccttgattgg catctttatg
    15901 agtctagcag ctgtgaccaa gattctcctt gggactgtgc tacttgtagc aattggttac
    15961 tatatgcctg ccctgctatt ttttgtagga attgggatgt ggcatttctt tatcagtgat
    16021 atgttggaac ctgtctatga aatcatccat gaaaaattgg cgacaaaata gaatgaagca
    16081 cttttggcta catacgcttc taagaaccta tagttcagtg atgatcatta tcattgcgag
    16141 ttttgcaatc ttactctctt acgctgactg ggattcacgt gaaaaggaag cccagagagt
    16201 agcccagcgt gtaactgcta gaacagtgag tgaaattgaa tattaccata gagagtcaac
    16261 ccagatagct caggctttag ttgaaaacca agctcgtatt gagggaatct ataaatactt
    16321 tagccttagc atgccagact atttttactg gcaattagag cggaaagctt cgccttatat
    16381 atcagtctct ctgtatgaaa atgttgatga cctctatgtt cgaaatgatt ttgtaactgg
    16441 ggtggccatt gcttttcaag attacaagga agtctatgtt tctactaaag acaaacgtag
    16501 tggagaaaaa atcagggctg aggatttcaa accagcagga aatagttttg ccattccggt
    16561 gtcagatcca gtgtcagatc aagatttagg agtgatttac atctccttgg atcctgctgt
    16621 tttataccat gccattgata atactagagg tcatactccg atggcagtaa cagtgacctc
    16681 accttttgat acggagattt ttcatattgg tgagacagtt gatagggaga gtgaaaattg
    16741 gctagttggc ttaacttctc atggatatca ggttcaggtg gcagttccta aaaactttgt
    16801 tttacaagga acagtgacta gctctgcttt gattgtgggt ttgagccttc tctttattgt
    16861 cattctttat ctgactttga ggcagacttt tgctaattac caaaagcagg tagtggattt
    16921 agtggaatcc attcaagtca ttgctcaagg cgaagagggg cgtcggattg acatttccga
    16981 aaaagatcag gaattactcc taatcgcgga gacgaccaat gatatgttgg atcgattgga
    17041 aaagaatatc catgatattt accagttaga gcttagtcaa aaagatgcca atatgcgagc
    17101 cttgcaggcg caaatcaatc ctcattttat gtataatacg ctggagttct tgcgcatgta
    17161 tgcagttatg cagagtcaag atgagttggc agatatcatt tatgaattca gtagtctctt
    17221 gcgtaacaat atttccgacg aaagagagac cctcctcaaa caggaattag aattttgccg
    17281 taaatacagc tatctctgca tggttcgcta tcccaagtcc attgcctatg gtttcaagat
    17341 agatccagag ttagagaata tgaagattcc caagtttacc ttgcaaccgc tggtagaaaa
    17401 ctatttcgcg catggtgttg accacaggcg gacagataat gtgattagca tcaaggctct
    17461 taaacaggat ggttttgtgg aaattttggt ggtcgataat ggtagaggaa tgtcggctga
    17521 aaagctggca aatatccgag aaaaattaag tcagagaaac tttgaacacc aagccagcta
    17581 cagtgatcaa aggcagtcta tcggaattgt caatgtacac gagcgttttg tgctctattt
    17641 tggagaccgc tatgccatta ctatagagtc tgcagagcaa gccggtgttc agtatcgtat
    17701 tacaattcaa gatgagtaga aagggagaaa atgtataaag tattattagt agatgatgag
    17761 tacatggtga cagaaggtct gaagcgtttg attccctttg ataagtggga tatggaggtc
    17821 gtcgcaacag tcagtcatgc cgatgaagct ctagaatatg ttcaggaaaa tcctgtcgat
    17881 gtcatcattt ccgatgtcaa tatgccagac aaaacagggc ttgatatgat tcgggagatg
    17941 aaagagatct taccagatgc tgcctatatc ctgctctcag gttatcagga gtttgattat
    18001 gtaaaaagag caatgaacct tagtgtggtg gactatttgg tcaagcctgt tgataaggta
    18061 gagctgggaa atctgctgga gaagattgca ggtcagctcg gcgagagagg gaagaaaagt
    18121 cagactctta gtcaagaatt agacgaggct ggatttgtta gttatttagg ggataaggag
    18181 aattggtgga taggtctatc caaggaaaaa caaggttcct tcgccattcc ctactatgtc
    18241 ttgggccaag actggcagat tttcatttct gaccaacccc tagatggttt agtcgttaca
    18301 ccttttgaag ctccttatca agaacacttt gaacgctgga agctgaatgc tgagaaaacc
    18361 ctcttttacg gttctgtaaa tctgcagcag tctgagagtc tctttgccta ttacgaaccg
    18421 atttataggg ttatcattca gggaaatctc aatcaaatcg tagaagagtt aaatctcttg
    18481 gagaaggtag ttcttgaaaa tacgccgcgt gttccgatta ctaaacagct ttttattcag
    18541 tttgtcatgg atgttttcca tttatttgaa catctcaaag ctgatgacct gacagacatc
    18601 gtcaaaacca ttcatgctat tcaatccttc gatgaattgg ttccttatat caaggaaact
    18661 ctgagcagct ttttcggtca ataccgtatg aatgaaaatg tggtcagtgt gctggaagtc
    18721 attggtcgtg attaccaaaa agagctttcc ctcaaggata tcagtaaggc tctctttatc
    18781 aatcctgtct atctagggca gttgattaag cgtgaaaccg attcgacttt tgcagagtta
    18841 ctaaacaaac aacgtattaa ggctgcccaa caacttttgc tttcaactag tgacagcatc
    18901 gaagatattt gttatgctgt tggttacagt aaccttggat atttctataa agttttccga
    18961 aaattgtgcg gaaaatcgcc aaaagcctac cgaaaacagg tagaaactat actataagat
    19021 ttgtattcct ttacaaaatg tgctataata taaatattat tattaggagg ttctatcatg
    19081 aaaaagaaac caatttatct atgggtcttg ctaatcttgt ctgcccttat ttcagttccg
    19141 tctctgtttg gaattgtgag tcccttgcct agtaaagaag cccttcgtac tgctcagaaa
    19201 caagttgcag gggtcaatgc tcagcaatta gaagaccagc ttaattatac ctatagagta
    19261 gcagaagcat ctcattctat ttttaatgtt gctttgattg tgctatctac tattttagtg
    19321 gtcgtagcga ttgtcttcct tgttcgtaaa aatttgcaat atgcaaacta tacttacgtt
    19381 ggctatgttt tgttagctat tattggttcg atttatggct atgttggttt acaagacgct
    19441 gtgcagttgg ttcaagatga gagcatgcgt ttgacagtga gtattggttc aaaagctgtt
    19501 agcattttct atatcgtcat caatgttctc ttcctagccc ttgtcttcta taagatgtgg
    19561 cgacaacaga aagccttggc agaagaagag gaaacagaag agcttgccta agtattgaca
    19621 aaaaagaact atcaagatac aatcttggta gttgtttttt gattatagat aaaatcatgg
    19681 aggtacatat gaagacaatt tctttagttt atattagttt gagtggcaac actgaaagtt
    19741 ttgtgacgcg cttgaaagac tatctcttgt cccagtacaa agggattgag gttcaaaaga
    19801 ttcatatcaa ggatttggtc aaggaaggca aaaatttcta tgaaatggac catccctatg
    19861 tcgctttttt gccgacctat ctcgaaggtg ggaatggcgt ggataacgga gatgttgaga
    19921 ttttgacgac accggtggga gattttattg cctatggtaa caatgctagt aagtgttttg
    19981 gtgtggttgg gtcaggaaat cgtaacttta ataaccaata ctgcctaaca gccaagcaat
    20041 acagtcaacg ctttggcttc cctgtattgg ctgactttga aatgcgaggc atgctggaag
    20101 atatcaaaca tgtcgcagct attatcgcag atttgtatga gttggaaaag gagaattaat
    20161 actcaatgaa aatcaaagag caaactagga agctagtcgc aggttgctca aagcacagct
    20221 ttgaggttgc agatagagct gacgtggttt gaagagattc tcgaatagta taaagttctt
    20281 ataagaggtg gttgaagttg ttcaactgtt ttttgagtat aaacagtttt taagaacgta
    20341 aaaaagcata agttcaggtc ttcaaaacct tgttcttatg ctttttatca tagaaatatt
    20401 tgctgaattt tctcttgaaa tgaaacctta tcttcatctc gcgcttgtcc cttaccctgc
    20461 ttttccgatt gcgagtgcgt agataaagaa gatggcgaag ccaaagagga aaatcaatcc
    20521 cgcaatggca aggtgtttga gccaagaagg aagatttttg ttttcacgcg ttaccaaggc
    20581 gtaattcaaa agagcaaaga aaggtgttgt caggaaagaa ccaatcatgg caaagcggag
    20641 catggttgaa acctgaccag cgaagaactt gataatgacg ataccgatga tagcagtgat
    20701 ggtcatccag atgttcaaag atttacgatt gtcctctttt tgactgatta gcagtcggag
    20761 agattcctga ttaacgcgag aatagccatc gataacagtt ataactgttc caaatataca
    20821 gaggaaggca ataaaggtaa tcaagtaacg ggaccattcg ccaagaacag aggcatacat
    20881 gcccacgaat tgagagatgt atttggctga agcagcttca accgcctgcc ctgtaggata
    20941 ctgaatcagt gctcccagtg ccacaaagaa gacggctagg atagctgttc caatataacc
    21001 agtgttaaag tcaaacagag cgtcttctgt gttaaagttg acggtctttc tcttttcagc
    21061 tgaccaaagt gaattgatgg ctgaaatttc aataggagcc ggcatccatc ctaggaggga
    21121 gacgatgaag ggcagagctg ccatttgcca aggtgtcttc tcgacaaaat cagaactgta
    21181 ttctggatgc ttgaccgccg caatgataac tgcaagaaca gtcgcaatgg ttaaggcaga
    21241 cataatccat ttgaccatgc cgtctaaaag tttgtagcct ccaaagagta gcatagccca
    21301 aatgattgca acgagaatga gggaccactg agtaatgcta agtccaatca ttgggaaggc
    21361 actggcgatg atagctgagc acagaatggc aacaccagcc gtgttgacca tagccgaaaa
    21421 gacattgagg ataaagaaaa tccagagata gagttttcct ttttcggcat aaccttcaac
    21481 caaagtcttt ccagtatcag ctgtgtattc agcaccaaaa cggaaaaatg gatatttaaa
    21541 gacattggct aagatgacca agagaagtag agaccaaccg taagaaccgc cagcttgagt
    21601 tgaggataca atgtgggaac ctccaacagc ggcagttgcc attaggattc caggtcccat
    21661 tgcttttagc ttgcttgccc aggttgattg atttaaggta atagcttgcg acatgataaa
    21721 tactcctttt tgaattttca gaataatctg tatatgtaat ctatattcta caaaaaattt
    21781 tggaaaaatg caagaatatt ttgaaaaaag atagaaaatt tacaaagaaa atctgaaata
    21841 actgttatga tatagcagat tgaaactaga atagtacacc tttgcttcta aaacattgtt
    21901 agaaatcgat ttgactgtcc tgatcgattt atcctgttct tatttcattt cactatagta
    21961 aggtgcagca ggataaagaa aaaccgagaa gtttctttct cggatttgct tattatgagg
    22021 ttcctatttt ctatgctcca agagttgatt gatgtgatct acttttttag cctctctttt
    22081 atagagaata gcccagatga tgagatagac aatcgcaaac tcgataatga gctggaggta
    22141 gaaaatccag tggaaaggga accaaccagc aagagttgct agtgggacaa agccagccag
    22201 cataaggaag aaatgagtca gagtggcacg aagcatgctc cagtcacggc tgaataagcg
    22261 gttgccaaag ttgaagagca taccgatggc tgcccagata agtgtgcagt agagcaagac
    22321 cagggcaccg tgaacctgat gctgatccat cacttggccg atgagagagt agggatttag
    22381 tggtgcgtag gtatttggtg cataaatgag tgaaaagagg atggagagga tgaggccgat
    22441 aagaacaccg gcagctgcat cgtgaaatac ttgttttttc atagttctaa tttctccttg
    22501 atggttttta gataacggcg tgaagagtag gtgaagcttt cgtttttcaa gaaaatttct
    22561 accagaccgt ttggcgtgag cttgaggtga gagatggaat cgatattgat gatttctgat
    22621 tgggaaattt ggataaaatt gcttggcaag agtttaagaa cctgatagag tcgcaaatca
    22681 atgctgtagg tctgactcgc ggtttctgct agaaccttcc gattctcgat atagaagcgc
    22741 tgaatcttgc caatctcaac tagatagacc tgatcatcga ttttcccttt gattttttct
    22801 ctttggtcca gattttctgc gaactcgatg actttctgga ctttatctgt cggctgaggt
    22861 gcttggacaa tcagcttttc ctcctcgtaa gtctcactaa tctgtagttc tactttcata
    22921 aatttctctc cttgtttttc atacaaaatt aatctcactt cttgtacacc tttattaata
    22981 ctcttcaaaa atctcttcaa accacgtcag cgtcgtcttg ccgtaggata gttgttgact
    23041 ttgtcagttt tatctacaac ctcaaaacag tgttttgaac tgtctgcgcc tagctttcta
    23101 gtttgctctt tgatttttat tgagtatacc actattttac tccctctggc aagggacttt
    23161 gtctatgtgg agggattggg ctcctatgtg gtggagcttt tctgttcttt ctgaaatatg
    23221 gtataatagc actaattaat ttctaggaaa atagatacag aaaggggctg aaagatgtct
    23281 catattattg aattgccaga gatgctggca aaccaaatcg cagctggaga ggtcattgaa
    23341 cgtcctgcca gtgtggtcaa agagttggta gaaaatgcca ttgacgcggg ctctagtcag
    23401 attattattg agattgagga agctggtctc aagaaggttc aaatcacgga taacggtcat
    23461 ggaattgccc acgatgaggt ggagttggcc ctgcgtcgcc atgcgaccag taagataaaa
    23521 aatcaagcag atctctttcg gattcggacg cttggttttc gtggtgaagc cttgccttct
    23581 attgcgtctg ttagtgtctt gactctgtta acggcggtgg atggtgctag tcatggaacc
    23641 aagttagtcg cgcgtggggg tgaagttgag gaagtcatcc cagcgactag tcctgtggga
    23701 accaaggttt gtgtggagga tctctttttc aacacgcctg cccgtctcaa gtatatgaag
    23761 agccagcaag cggagttgtc tcatatcatt gatattgtca accgtctggg cttggcccat
    23821 cctgagattt cttttagctt gattagtgat ggcaaggaaa tgacgcggac agcagggact
    23881 ggtcaactgc gccaagcaat cgcagggatt tacggtttgg tcagtgccaa gaagatgatt
    23941 gaaattgaga actctgacct agatttcgaa atttcaggtt ttgtgtcctt gcctgagttg
    24001 actcgggcta accgcaatta tatcagtctc ttcatcaatg gccgttatat caagaacttc
    24061 ctgctcaatc gtgctatttt ggatggtttt ggaagcaagc ttatggttgg acgttttcca
    24121 ctggctgtca ttcacatcca tatcgaccct tatctagcgg atgtcaatgt acatccaacc
    24181 aagcaagagg tgcggatttc caaggaaaaa gaactgatgg cgctggtctc agaagctatt
    24241 gcaaatagtc tcaaggaaca aaccttgatt ccagatgcct tggaaaatct tgccaaatcg
    24301 accgtgcgca atcgtgagaa ggtggagcaa actattctcc cactcaaaga aaatacgctc
    24361 tactatgaga aaactgagcc gtcaagacct agtcaaactg aagtagctga ttatcaggta
    24421 gaattgactg atgaagggca ggatttgacc ctgtttgcca aggaaacctt ggaccgattg
    24481 accaagccag caaaactgca ttttgcagag agaaagcctg ctaactacga ccagctagac
    24541 catccagagt tagatcttgc tagcatcgat aaggcttatg acaaactgga gcgagaagaa
    24601 gcatccagct tcccagagtt ggagtttttc ggacaaatgc acgggactta tctctttgcc
    24661 caagggcgag atggacttta catcatagat cagcacgctg ctcaggaacg ggtcaagtac
    24721 gaggagtacc gtgaaagcat tggcaatgtt gaccagagcc agcagcaact cctagtgccc
    24781 tatatctttg aatttcctgc ggatgatgcc ttgcgtctca aggaaagaat gcctctctta
    24841 gaggaagtgg gcgtctttct agcagagtac ggagaaaatc aatttattct acgtgaacat
    24901 cctatttgga tggcagaaga agagattgaa tcaggcatct atgagatgtg cgacatgctc
    24961 cttttgacca aggaagtttc tatcaagaaa taccgagcag agctggctat catgatgtct
    25021 tgcaagcgat ctatcaaggc caatcatcgt attgatgatc attcagctag acaactcctc
    25081 tatcagcttt ctcaatgtga caatccctat aactgtcctc acggacgtcc tgtcttggtg
    25141 cattttacca agtcggatat ggaaaagatg ttccgacgta ttcaggaaaa tcacaccagt
    25201 ctccgtgagt tggggaaata ttaaaagtat aaaaaagtct gggaaaaatt ttcaaaatca
    25261 gaaaaacgca taaaatcagg tgttcaaaaa ccttgatttt atgcgtttta tcatggaaat
    25321 agttacttca tgttttccta attcttttcg aaactctttt taaaccacgt cagttttatc
    25381 agtaatctca aaacagtgtt ttgagctaat tttgccagtt ttgtctgtaa catcgaagtt
    25441 gtgtttgacc actctgcgac tggtttccta gtttgctcta tgattttcac agagtattaa
    25501 attgcgattt tgccaagttt ctttattcgt ctaaaagtag agtctgttct atgcgtctaa
    25561 tgtacgaatt aggttgacca tttcaatagc tccttgtgca cactcagaac ccttatttcc
    25621 tgctttggta ccagctcgtt ctatggcttg ttcaattgta tctgtcgtta gcacaccaaa
    25681 cataacagga atttcgctat ttaaactgat ttgggcgatt cccttagata cctcgctaca
    25741 tacataatca taatgacttg tattccctct aatgacagct cccaagcaga taattgcatc
    25801 atatttttta ctttttgcca tttttgatgc aatcagtggt atttcaaaag ctcctggaac
    25861 ccaggctacc tcgatatctt tctcgtttac attctctctt ttgagattat ctagtgctcc
    25921 agataataat tttgaagtta taaattcatt aaatctcgct acaacaatac ctattttaat
    25981 attgtttgct actaaattac cttcataagt gttcatttat ttttcctcca tatttaaaat
    26041 gtgacccatt cgatttttct ttgtttctaa ataaaaacta tcgtaaggat tggcttctat
    26101 ttcgattgat attctactgg aaatggtaat tccatatttt tctaactgtt caaccttgtc
    26161 aggattattt gtcagtaaat gaagtgactg aagtcccaga tctttaagca tttgtgctcc
    26221 aatatgatat tctcttaaat caccttcaaa gcctaatgca agattggcat caagcgtatc
    26281 catgccttga tcttgtaaat gataggcttt taatttattg ataagtccaa ttcctcgtcc
    26341 ctcctgtcgc aagtaaagta agacacccga accattctca acaatcattt tcatagcttt
    26401 atcgaattgc tgtccacaat cgcaacgtaa agagcctaaa acatcccctg ttaaacattc
    26461 ggagtggacc cgacataata cattggcttc atcctctatg tttcccataa taagagcaag
    26521 atgatgttcc ccatttagtt tatctatata gctaattgct ttgaaattac cgtatctagt
    26581 aggcatattg acagttgaaa ctcgttctac cagctgatca tatacttttc tatattcttg
    26641 taattctttg atggtaatta gtggaatgtt gtgtttcttc gagaactgaa ttaaatcatc
    26701 tgttctcatc attttgccat catgattcat tatttcacaa cataggccac actcttttag
    26761 tccagctaat tttaataaat caacagttgc ttctgtgtgt ccatttcttt ctagaacacc
    26821 accttttttt gcaattaaag gaaacatgtg tcctggcctg cgaaaatcag agggtgttat
    26881 atcttcagct acacacatac gtgcggtcag tcctctttcc tcggcagaaa tacctgtggt
    26941 cgtttcttta taatcaattg aaactgtaaa agcagtctta tgattatctg tattgttttc
    27001 aaccataggt gaaagcatta attgattagc taaactttcg ctcataggca tacaaattaa
    27061 tcctttggca taagtagcca taaaattaac attttctgtt gtagctgctt gtgcagaaca
    27121 aattaagtct ccttcatttt ctctatcctt gtcgtctata acaagaacaa gtcgtccctt
    27181 ctgcaatgct tctaatgctt cttgtatttt tcgatattcc attgactgat tatcctttct
    27241 gctaaaatcc attttgatat aatagttcct tagatatttc tgattttgga gagttatcca
    27301 tcagtttttg cacatattta cctaagatat cattttcaag atttactgta ttcccgactt
    27361 gtttactttt aagaatggtt tgttccaagg tatgagggat aacagatact gaaaagttta
    27421 ctttggagac tttagcgaca gtcagactaa tgccgtcaat tgtaatagat cctttttcaa
    27481 ctattaaatc taaaatttct ttttgtgtgt tgatttgata ccatacagca ttatcatctt
    27541 tttttattga cgagattttt cctgtaccat caatgtgtcc tgtaacgacg tgacccccaa
    27601 gtcgaccgtt gacagataag gctctttcta gattcacctc acttccatgt tttaatagag
    27661 taagagctgt tcgactccat gtttcattca ttacatcaac tgtaaaggat tgatggttga
    27721 aatgagtaac tgtaagacag ataccattta ctgctatact atcgcctaaa tggatatccg
    27781 ttaatatttt tgaggcttta attgatagtt tacaattacg agagtctttc tgtattcttt
    27841 caacttttcc gatttcttca attattcctg taaacatgga taaatcactt cactttctat
    27901 gagatagtca tttcctattt gagaaaaagc ataaggtttc aatctaatag cgtcatttgg
    27961 caaagaaatg ccctcacctc cgacaggaaa cttggcactg cctccaaaaa tttttggtgc
    28021 aatatatatt ttcagctcat caacaatttg ttgttccaaa gcactccaat tcattagact
    28081 gcccccttct agaactaggc tatcaatctg catgtttcct agatgttgca ttaaactcga
    28141 taagtctata tgattgcctt ttttctttat ggaaagtatt tcacagccat gattttgata
    28201 tagcttcatt ttatttttgt cttcagagga agtggcaatg taagttttaa tatcatttgc
    28261 tgtttttacg attttagagg taagaggagt tcgtaaatgt gtatcgcata tgatacggat
    28321 aggatttttc ccttcctcca atctacatgt cagcaaagga tcgtcttgaa taacagtatt
    28381 gactcccacc ataattgcac taacatggtg tcgtaactga tgcacatgct ttcttgcttc
    28441 ttcttcagta atccatttgg attgatttgt tttagtggct atttttccat ccattgacat
    28501 tgcatatttc ataaaaacat agggtacatg ctgggtaata tactttctaa aactttttat
    28561 taagttaaga cactcatttt ctaaaattcc aacagtaact tgaagattat tttcctcaag
    28621 tatctttact ccttttccag atacaatagg attacagtct aggcttccaa tgactactct
    28681 tgtaatacca ctatcgatta tagcatctat acagggaggt gttttcccga agtgacaaca
    28741 gggttcaagt gttacataaa gcgtcgctcc gacaggggat tctctacagt ttttaagagc
    28801 atttctctca gcatgtgggc caccaaaaaa ctcatgataa ccttgtccga taatgtgatt
    28861 atcttttaca ataactgcgc cgaccatagg attgggattg acgtaaccag cccctttttg
    28921 tgccagtttt attgctaatt tcatatattt tgaatcgctc atctcactac ctccaaaaaa
    28981 atatgccttg aataggggac tactcaaggc atacaaaaga aaacttatgc gattaacaaa
    29041 aatgctctga aatgacaagt aatcatttca gagcacgcaa aaagcacaaa tatactttta
    29101 tcttctttca tccagactat actgtcggct ttggaatttc accaaatcat gcctttcggc
    29161 tcgtgggcta taccaccggt agggaatttc accctgccct gaagatagtt attcaattac
    29221 agatgattat agtacttaat tttgaatatg tcaacagata aataccgatt gtttttgata
    29281 tactgtattt gtgataatcg attctcgctc ctcggataaa gaaaatatga tatactagat
    29341 aaacgaaata agagagaagg aatactatgt acgcatattt aaaaggaatc attaccaaaa
    29401 ttactgccaa atacattgtt cttgaaacca atggtattgg ttatatcctg catgtggcca
    29461 atccttatgc ctattcaggt caggttaatc aggaggctca gatttatgtg catcaggttg
    29521 tgcgtgagga cgcccatttg ctttatggat ttcgctcaga ggatgagaaa aagctctttc
    29581 ttagtctaat ttcggtctct gggattggtc ctgtatcagc tcttgctatt atcgctgctg
    29641 atgacaatgc tggcttggtt caagccattg aaaccaagaa catcacctac ttgaccaagt
    29701 tccctaaaat tggcaagaaa acagcccagc agatggtgct ggacttggaa ggcaaggtag
    29761 tagttgcagg agatgacctt cctgccaagg tcgcagtgca agcaagtgct gaaaaccaag
    29821 aattggaaga agctatggaa gccatgttgg ctctgggcta caaggcaaca gagctcaaga
    29881 aaatcaagaa attctttgaa ggaacgacag atacagctga gaactatatc aagtcggccc
    29941 ttaaaatgtt ggtcaaatag gagcagagaa tgacaaaacg ttgttcgtgg gtcaagatga
    30001 ccaacccgct ctacatcgcc tatcatgatg aggagtgggg tcagcccctc catgatgacc
    30061 aagcgttgtt tgagttgttg tgtatggaaa cctatcaggc aggcctgtct tgggaaacgg
    30121 tactcaacaa acgccaagct ttccgagaag cctttcatag ctatcaaatt cactcagtcg
    30181 cagagatgac tgacactgaa ttggaagcta tgctggagaa tccagctatc attcgaaata
    30241 gagccaagat ttttgctaca cgcgctaacg cccaagcttt tctacagtta caggcagagt
    30301 acggctcttt tgatgcctat ctttggtctt ttgttgaggg gaaaactgtc gttaacgatg
    30361 ttcctgatta tcgccaagcc ccagctaaaa cacccttatc tgagaaatta gccaaagatc
    30421 tcaaaaaacg aggcttcaag ttcacaggcc cagtcgccgt attgtctttt ctacaggctg
    30481 cagggctagt tgatgaccac gagaatgatt gtgagtggaa aggtcttaaa tgatgtctaa
    30541 caaaaataag gaaattctga tttttgcgat tctctataca gtcctctttg tgtttgatgg
    30601 cgttaaattg ctggcttctt taatgccata tgtcattgca aattatcttg tttatgtagt
    30661 tttagcttta tatggctcct tcttgttcaa ggatagattg atccaacaat ggaaggagat
    30721 tagaaagact aaaagaaaat tcttctttgg cgtcttaaca ggatggctct ttctcattct
    30781 gatgactgtt gtctttgaat ttgtatcaga gatgttgaag cagtttgtgg gactagatgg
    30841 acaaggtcta aatcagtcta atattcaaag tacctttcaa gaacaaccac tactgatagc
    30901 tgtttttgct tgtgtcattg gacctctggt agaagaatta tttttccgtc aggtcttatt
    30961 gcattacttg caggaacggt tgccaggttt actaagcatt attctggtag gacttgtttt
    31021 tgctctgact catatgcaca gttttgctct atcagagtgg attggtgcag ttggttactt
    31081 aggtggaggc cttgcctttt ctattattta tgtgaaagaa aaagagaata tctactatcc
    31141 cctacttgtt cacatgttaa gcaacagcct ctccttaatc attttagcta tcagtatagt
    31201 aaaatgaaa
//
LOCUS       DAVDFK010000022        29529 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.22, whole genome shotgun sequence.
ACCESSION   DAVDFK010000022 DAVDFK010000000
VERSION     DAVDFK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.22"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(105..1529)
                     /locus_tag="VUR04_001262"
     CDS             complement(105..1529)
                     /locus_tag="VUR04_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET5341157.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VUR04_001263"
     CDS             complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VUR04_001263"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET5341158.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAVQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLLTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="VUR04_001264"
     CDS             complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="VUR04_001264"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET5341159.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6516..7694)
                     /locus_tag="VUR04_001265"
     CDS             complement(6516..7694)
                     /locus_tag="VUR04_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5341160.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFCGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7774..8645)
                     /locus_tag="VUR04_001266"
                     /pseudo
     CDS             complement(7774..8645)
                     /locus_tag="VUR04_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
     gene            complement(8648..10549)
                     /locus_tag="VUR04_001267"
     CDS             complement(8648..10549)
                     /locus_tag="VUR04_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5341161.1"
                     /translation="MIVLQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(10975..11250)
                     /locus_tag="VUR04_001268"
     CDS             complement(10975..11250)
                     /locus_tag="VUR04_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET5341162.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11356..12195)
                     /locus_tag="VUR04_001269"
     CDS             complement(11356..12195)
                     /locus_tag="VUR04_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5341163.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKNHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12337..13185
                     /locus_tag="VUR04_001270"
     CDS             12337..13185
                     /locus_tag="VUR04_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET5341164.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGVKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13278..14195)
                     /locus_tag="VUR04_001271"
     CDS             complement(13278..14195)
                     /locus_tag="VUR04_001271"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET5341165.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            14503..14661
                     /locus_tag="VUR04_001272"
     CDS             14503..14661
                     /locus_tag="VUR04_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341166.1"
                     /translation="MTVKFTKRDNLGKMFEEFPKLPDLKQVTFPDDKEKSQSNKEKLD
                     DCFPTTPI"
     gene            14633..14838
                     /locus_tag="VUR04_001273"
                     /pseudo
     CDS             14633..14838
                     /locus_tag="VUR04_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1980 domain-containing protein"
     gene            complement(15149..15442)
                     /gene="rpmA"
                     /locus_tag="VUR04_001274"
     CDS             complement(15149..15442)
                     /gene="rpmA"
                     /locus_tag="VUR04_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET5341167.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(15459..15803)
                     /locus_tag="VUR04_001275"
     CDS             complement(15459..15803)
                     /locus_tag="VUR04_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET5341168.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(15819..16133)
                     /gene="rplU"
                     /locus_tag="VUR04_001276"
     CDS             complement(15819..16133)
                     /gene="rplU"
                     /locus_tag="VUR04_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET5341169.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVC
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(16170..16257)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(16352..16928)
                     /locus_tag="VUR04_001277"
                     /pseudo
     CDS             complement(16352..16928)
                     /locus_tag="VUR04_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
     gene            17419..17718
                     /locus_tag="VUR04_001278"
     CDS             17419..17718
                     /locus_tag="VUR04_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET5341170.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVISIDFNPAVIDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(18060..19034)
                     /gene="pta"
                     /locus_tag="VUR04_001279"
     CDS             complement(18060..19034)
                     /gene="pta"
                     /locus_tag="VUR04_001279"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET5341171.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(19078..19974)
                     /locus_tag="VUR04_001280"
     CDS             complement(19078..19974)
                     /locus_tag="VUR04_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5341172.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHTRLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(19971..20789)
                     /locus_tag="VUR04_001281"
     CDS             complement(19971..20789)
                     /locus_tag="VUR04_001281"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET5341173.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(20773..21444)
                     /locus_tag="VUR04_001282"
     CDS             complement(20773..21444)
                     /locus_tag="VUR04_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET5341174.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            21572..22141
                     /locus_tag="VUR04_001283"
     CDS             21572..22141
                     /locus_tag="VUR04_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET5341175.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            22254..23213
                     /locus_tag="VUR04_001284"
     CDS             22254..23213
                     /locus_tag="VUR04_001284"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET5341176.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            23223..24338
                     /locus_tag="VUR04_001285"
     CDS             23223..24338
                     /locus_tag="VUR04_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5341177.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            24343..24690
                     /locus_tag="VUR04_001286"
     CDS             24343..24690
                     /locus_tag="VUR04_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET5341178.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            24698..24913
                     /locus_tag="VUR04_001287"
     CDS             24698..24913
                     /locus_tag="VUR04_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET5341179.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            24996..25637
                     /locus_tag="VUR04_001288"
     CDS             24996..25637
                     /locus_tag="VUR04_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET5341180.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            25655..26344
                     /locus_tag="VUR04_001289"
     CDS             25655..26344
                     /locus_tag="VUR04_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET5341181.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26341..27021)
                     /gene="radC"
                     /locus_tag="VUR04_001290"
     CDS             complement(26341..27021)
                     /gene="radC"
                     /locus_tag="VUR04_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET5341182.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(27064..29355)
                     /gene="pcrA"
                     /locus_tag="VUR04_001291"
     CDS             complement(27064..29355)
                     /gene="pcrA"
                     /locus_tag="VUR04_001291"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET5341183.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKIILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         9005 a         6305 c         5322 g         8897 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt cacatcaaaa
      121 acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg cactccagct
      181 ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt tttattatta
      241 atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt gaaatcattt
      301 gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat agcctcctct
      361 acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca tgccactttc
      421 atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc acgtttgatt
      481 ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagctcca aatgaagtcg
      541 gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc accaactgtt
      601 aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact ttcgagaaca
      661 atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc cgcaacaatt
      721 tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc tttcccacca
      781 agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc aataggagtt
      841 gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc cccaatttct
      901 gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc ttcaaatgct
      961 ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat gaccacattc
     1021 cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata attaaaagga
     1081 gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt gtttttactt
     1141 gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc ttcctcagca
     1201 gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt aatccctttt
     1261 gctacttctt tggcaaggat agtaccaatt ttttccttat cgcgttctaa aatagctgct
     1321 gttttatgca aataagccgc acgttcaatt gctgataaag ctcgccatgc tggcagggct
     1381 gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg aactgtaccc
     1441 aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga tttccatttt
     1501 ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg attaagatat
     1561 attttaccaa attttcagaa aatcacaacc ctttttgcaa aatttttgag attattttca
     1621 caagcttgat ttttcaaagt atactcaata aaaataaaaa aaatccacta catcaaggcg
     1681 agactaatgt ggtttgaaga aattttcgaa gagcgtgaat gagtatcatc tatagtaaaa
     1741 taaaaaaact gaacaatttg gttggggaca gtcaaaccaa tttctcacaa tgttttagaa
     1801 acaagggtgt gctattccaa tttcaggcta ctataactgt catagattgc tgaaacaaag
     1861 tctaggtaaa agtcttcata ataaaaagac cccctatcaa gtgttcaaaa actttgatag
     1921 gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct gttagccagg
     1981 ttctttctat tctttcaatt tcaatgaatg gattttttac caatactcat aactgggaat
     2041 ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga cagctagact
     2101 aatatcattt aaaacattat cttcttttga gcgactgttg gttagcaaca tagctaaatt
     2161 tcctgcattt tcaaattgat agggttctga tttagcattc acaactacca agaggtgttc
     2221 tttgccgtga acttcataga taaggcagcc gctatgttca atcgcagaat gcacaaagac
     2281 atgatggtaa atttcatcat agctagagta agaaaaggca ccagtttttg tcttcaatcg
     2341 gatgacttga cggataaact caatactgtc ttgacgctca ttaatcaagt tccagttcac
     2401 ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat catcatgggt
     2461 caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt gaccgatttc
     2521 cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga ccttgcgcat
     2581 gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa gattgtaatt
     2641 gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc ctaattcacg
     2701 acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga caaaacctga
     2761 cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt cattaaagaa
     2821 accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag gggcaagacc
     2881 tgttcccata tcccatcctt ctccatagag gataatgttg gagtcgattt catccaagct
     2941 ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa aacggaagcc
     3001 gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact tgcgaaacat
     3061 ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg taccatctgg
     3121 attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa caactgagaa
     3181 ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat aagcttgaac
     3241 catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg aaaaactagt
     3301 ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat ttccatcctc
     3361 atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt agcccagctt
     3421 cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag cctgaacagc
     3481 acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt tagtcaaatc
     3541 acgaatgtgc atttcacaga taactgcctt acatggattt tccaagcgcc aagtagcctc
     3601 cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca gaatagctga
     3661 acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg tttggtgatg
     3721 agggaattgg acttgatact gataagtctt acctaccaaa tcttcttcaa catccaaact
     3781 ccagacaccg attgtattgt ccttatgatt ataagagtag ctattgcctc ttttcatctc
     3841 aaaagtcttc caaacgggtg catcattagc agctgattca taaacgacaa cttgcacttc
     3901 tgtcgctgta ggtgaccaga gagaaaaatg agcctgattg tcctctacac ggcaacccaa
     3961 ttctccttgg taaccccaat gatgatcaaa actagcactg ttaatggcct tatcaaaggc
     4021 aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag agtaataaat
     4081 cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat taaaacggat
     4141 agaatattct ttactagttt gacctgtatg aaccacaaaa ttcaagcttt ctataacatg
     4201 tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt aggttagcaa
     4261 atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc cattcttacg
     4321 atggtaatga atgcgcatag ggtagttata cattttttat ttttcctttt tactttgttt
     4381 ctatttcact aataaatttt tgtcaatctc gtctcaatta acagacatag tcatattctc
     4441 taaactctgt ttttaaacga tccattacaa actttctagc catgcctcat ctctgacctg
     4501 gataccaagt tcttgtgctt tttgcagttt acttccagcg tctgcaccta ccacgacgag
     4561 gtcggtcttt ttagaaatac tacctgtcac tttggcaccc agactttcga gtttactttt
     4621 agcttctgag cgcttgagtc gttccaattt tcctgtcaat accacggtca aacctgacaa
     4681 ggccgcatcc gctactaccg tctgtccttt atagtccaga ttgaccccag tttctttcaa
     4741 ttctctgagc agaatttcag agccttctgt cgcaaaataa gtctgaagac ttttggcaat
     4801 cacgccacct agactttcaa tactagccac ttcctctgaa tctgcctgag acagattttc
     4861 aattgaatgg aaatattgaa gtaaaagctg actaaccttg cttccgacat gacgaattcc
     4921 caaaccaaat aagagcttct cggcagaatt ttcctttgat gcttggatag cctgatacag
     4981 tttagcagcg gacttttcct taaccccctc taaaaggagg aaatcctctt cttgcaaacg
     5041 ataaatatcc gccacatcct tgactaaatt agcagcaaaa agcttctcaa caatagatgg
     5101 accaaggcct gtaatattca tagcatcacg agaagcaaag tgaatcaagc cttccatgat
     5161 ttgagcaggg caacgcggat tgatacaacg tagggccact tcatcttcaa agtgcaacaa
     5221 gtcagagtta caacttggac agtttgtagg gatatctagt ttttcttcag aaacccgttt
     5281 ggactctacc acacgtaaaa cggcagggat gatgtcacca gccttatata caatgaccgt
     5341 atcgtctttt cggatatctt tttcagcaat ataatctaca ttgtgcaggg tcgcacggct
     5401 aacagtcgta ccggcaagtt gtactggtgt tagattagca gttggagtta caacaccggt
     5461 acggccaact gtccagtcaa ctgataagag ttgagcttct ttttcttcag cagggaactt
     5521 gtaggctact gcccactttg gagccttaac ggtaaaacca agttcttctt gacttgctag
     5581 gtcgttgacc ttgattacca ctccatcaat atcgtaaggc agattttccc gttcctgtcc
     5641 tacttcttgg ataaaattcc agatttcatc tatgttttca gccaagattc gcttaggatt
     5701 gaccacaaaa cctagttgtt ctaggtactt caaacccttt tcttggctat cacgagttga
     5761 agggctggct tcttgataga gaaacgttgc aagattacgc ttggcaacta ctgctgtatc
     5821 caactgacgc agagttcctg ctgccgcatt acgaggatta gcaaattcag gctctccatt
     5881 ttcttggcgc gcttggttaa cttggtcaaa ggaagcgcgt ggcatgtaac attccccacg
     5941 aactgtgata tctagttctt ctggcaaagt caaagggatg tccttaacac gcttgaggtt
     6001 ttctgtgata ttttcaccaa ttgaaccatc tccacgtgtt accccagcaa ccaaaatccc
     6061 cttttcataa gtcagcgaga tagataagcc atcgattttc agctcacaaa tataggtcgg
     6121 atgagccact tccttacgaa cacgcgcatc aaaagcatct agctcctcac gtgaaaaagc
     6181 atcctgcaaa ctataaagag gatactgatg actgtatttt tcaaaaccat ctaaaacctt
     6241 gccaccaaca cgatgagtcg gactgtctgc tagcacttgc tctggataag cagtttctaa
     6301 ctcgaccaac tcacggtaaa ggcggtcata ctcactgtct gaaaccgagg gattatcgct
     6361 ggtatagtac tcagtcgcat agcgattgag caaagcgact aactcattca ttcttttatt
     6421 cataagacca ttttaccata aaacaagccc tcctcacaaa cgagaagggc ggaaaaaaca
     6481 cttagtttga aattattttt gaaactcaag caaccttata tcaatttttc aaaatgagtt
     6541 cgaacataaa taaacgatat acaagacaag atgataacac cacttccaat tatcaggaaa
     6601 gaagagagat gtacacttgg caagactgtc ataaatcctt ttgcaatagg cataaataga
     6661 atagctaagg taaaaattgt actcagtact cttccaagaa attcgctctc aaccttggtt
     6721 tgtacttgag taaaaaagtg aatattaaaa atcgtcataa acaattcaca aactaaattt
     6781 ccagaaaagg aaagaaaagt tggaagtggt aatcccatca taaaaactcc gacacctgtc
     6841 aaagccagta aaatcaaaag attataaata ttagctttaa ttttactagc tagaagagcc
     6901 ccaatgatgg aaccaatagc ccccatagtt aaaatacttg cataggctcc ttctgacccg
     6961 taaagctgat tcgaaaaggg aagtagaaat tcaaaagctg caaaaaagaa attaacgctg
     7021 gaagctacca gcaaaaggaa gaaaatttct tgctgatgcc agatatagtg taacccatcc
     7081 ttgatatcta caaaaatatc tctcccagta aaagcctttt tctcttgaac ttttgcttcc
     7141 tcttttggaa ggaaagccac tagaacaaaa gcaatgaaaa aagtcagcga gtctagcagt
     7201 agcgtcatat ggagacttgc aaactgtaaa acaaggaagg aaagaacagg agagctaaca
     7261 cctacaacct gcaaaaccag ctctaagcga gaattataga tcacaatctc atctttctcc
     7321 accacttcag ttatgatagc tttattggct gtgcgagaaa aggcaaaagc aatagcctgc
     7381 acaatgttag caacaatcaa agcgccaatc atccagctat cattccttat gaaagaaata
     7441 gccagacaaa gaatcccaca aacaagatct gccgtcatta aaatcttacg acgagaaaaa
     7501 cggtctgaaa taactccgca aaagggattg acgagaatag atgtgacgag ctcagaaatc
     7561 tgatacattc ctaaaactgt ctgtcctata gtccccatag aagccaacca gacactattt
     7621 ccataatcat agagcatatt tcccatttta ttgatagccc cacggctaat caactgcact
     7681 gcataacgat tcatattaaa gctcctctca aattttgaaa ctattgtatc aaaaccgaaa
     7741 ggagcttttt attttttccc ttatttggga aaattaactt ttgacaaatt tttcgtagtg
     7801 ttcctgataa taggctactt gctctggaag acctaacaca tcaaaaatat gcatggcctc
     7861 ttgcatctgc ttacagcctt ctttacactg tcctttttga tataaggcaa aaccttttaa
     7921 ataatggaaa acattacgct cataaagctt aatacctttg tcaataatct tctctgtata
     7981 agcctcaaaa tagttggcat tataaaaaga agaatgctct aaacaatgct ggtaacaatt
     8041 gagggccaaa atcaacacta atctcttatg gcgactaatc tcttggtaaa attcctccct
     8101 ctccataact tctctaccaa tccgagtgac atagtctaca tcgtagaaac tatagaggtt
     8161 accgaaaaga atcaactcat acatggtcca ttcttctgtt ttgaagagat aatctactac
     8221 cttatccaaa tcatcctgct tcatatcata acttcataac tcgcatctct ttgacaaatc
     8281 agaccttgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga actcttagac
     8341 ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga atagtaaagt
     8401 gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct tgccttatcc
     8461 atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg ggagactgcc
     8521 aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga ttcgcctgct
     8581 gcttccttta aagaataatt tccacttgtt cgaaattcac gaaatacttt tccaagatgt
     8641 tccatcttta cacctgctct gataattctt cccactcaag catagcttct tcctgacgat
     8701 ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca
     8761 acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca gcttctagac
     8821 tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg gcctgatagt
     8881 cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca gtctgactca
     8941 tttctgctgt tgctttcttc tcaacatagt agtcgtaatc tccaaggtag agagttgaac
     9001 cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa cgatcatgac
     9061 tgacaaacag caaggttcca tcaaagtcaa tcaaggcatt ttctagcact tccttactat
     9121 caatatccaa gtggttggtc ggctcatcca gaatcaaaaa attattgttt tccatagaca
     9181 atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact gattttttaa
     9241 catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact tctggtgtca
     9301 gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc ttgctttggg
     9361 tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttctccc ttgataaaag
     9421 gaatctggtc cacaatagac ttgataaagg ttgacttgcc gataccattt ggaccaacga
     9481 tagcgacagc attcatctta cgaagatcta ggttgatagg ttgtgacaag acttccccgt
     9541 cataaccaat agcagtattt tcaacagtca aaacaacatt gcccgacgtt ttttcagact
     9601 ggaaggtcat gttggctgct ttcttgccag cttcaggctt gtccaaacgc tccatttttt
     9661 ctagttgttt acggcgagat tgagcacgtt tagtcgttga agcacgaact agattgcgat
     9721 tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt tttgcctcag
     9781 taactagctt ttgctccttc aactcgacaa aacgagagta attccccaca tagcgatcca
     9841 aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt
     9901 ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc caggagatgg
     9961 tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc ttttcaagga
    10021 gcattttggc aagtgccaaa cgagtatttt gaccaccaga aagctcagca attttcatct
    10081 gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatgtca gcttcatagg
    10141 taaagccacc tgcttggcga aaattctcag ataagcggtc ataatctgac atcagtttat
    10201 ccaaatcctc accagacttt tcacccatct ccagctccat ctgacgcagt tgtctctccg
    10261 tccgacgcaa atcattaaag acatgaagca tttcatcgta gatggtattt tcagactcaa
    10321 aacggctatc ttgggctagg taagacagag aaatatcttt tttcttattg atttctccgc
    10381 tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct gcaccatttt
    10441 tcccaacaag agcaatccga tctcgttcat caacctgcag gttgatatta tcgaaaagaa
    10501 cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aacaatcata agagtagtat
    10561 agcatgtttc cctaaggcat tcaagataat cgtaagtctt ttagtacaac ttttataaca
    10621 taaaataaac taaattatgt atattttata ttagattcct tcactatctt gttggatttt
    10681 ctaaccagct aatcttgttt caaatagtta tcgcacaagt ctattattta attcttttca
    10741 tcatttacgt acgtatagca gattgaaata agatgagaac aaatcgattg ggaaagtaaa
    10801 attaatttct ataaatgttt tagcaattgt ttcgtactat tttagattca gtctactata
    10861 tacaatattt tcggaacatt caacttttta actctattta ttactagatt tcataattaa
    10921 aaagcctact gaccaagcta gaaagcttga tacaataggc tttttaaaga ctgattattt
    10981 aacagcgtct ttaagagctt taccagcttt gaatgctggt actttagaag ctgcaattgt
    11041 catttcttta ccagtttgtg ggttgcgacc tttacgttct gcacgctcac gaacttcaaa
    11101 gttaccaaaa ccgatcaatt gaactttttc accagctgca agatagtcag ctactgctgc
    11161 aaatacagct tcaactgctg ctgctgagtc tttcttagtc aactctgtag cttctgctac
    11221 tttagcgatc aaatcttgtt tgtttgccat gttaatgatt cctccaaata atttctaatt
    11281 aacaaatata atcatatcct aaaatccctt ttaggtcaag ttaaaaacgc tatttcttcc
    11341 cattttattt attttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
    11401 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
    11461 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
    11521 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
    11581 agttccacga cctttaacca ttggctgcaa ttcatggttt ttcatttgca tgacaacacg
    11641 gatattgaga agagagctca acaagccagt tacacggcta attcgtccac ctttgacaag
    11701 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
    11761 agataaaatt gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
    11821 gaatttcagg gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag
    11881 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
    11941 aagaatctgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
    12001 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
    12061 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
    12121 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
    12181 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
    12241 ctaattatat caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa
    12301 tttgatataa tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt
    12361 tttaccattt tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc
    12421 catcatctct ttgaaggagg ggcgacaggt attaccctca tcacctttta tctttttaaa
    12481 atccctgttt ccctcatgaa cctgctgatc aatattcccc ttttcatcct agcttggaag
    12541 atctttggag tcaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg
    12601 ttagcttttt ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca
    12661 gcccttatag cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt
    12721 acaactggcg gaactgatat tctagctcgt attctcaaca aatacactca tatatccata
    12781 ggaaaactgc tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag
    12841 gatttgagat tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat
    12901 ttgattggtg aaggaggata tgccggcaaa ggatttatga ttatcacaaa acgtcctgac
    12961 caacttgcta aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttctggtcaa
    13021 ggctactata gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt
    13081 gtgaaaacga aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa
    13141 gcccatgaaa tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg
    13201 tgacctcaaa agttagacta aatcatctat cttttgggtt acagacaacc tcttttttat
    13261 tttatttact caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga
    13321 tccactaatt ggtcaactga gtcaaatttg gtcatatctc gaatgcgatc aagccaataa
    13381 accatgacgg tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt
    13441 gcttcttctc catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt
    13501 ctttgaatct caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa
    13561 agcactaaat tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc
    13621 atacctcttg atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct
    13681 aaaatagctt gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga
    13741 acaatgataa cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa
    13801 ccaaatgtat aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt
    13861 gcaaagaatt cttgtgcagt gagactagcg aattgactac taaaatcaag gagatataat
    13921 tcttctacac cttcgcgctt taattttctt tcacgttcag cagggttcaa aatatgcaaa
    13981 aacaaatctg gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg
    14041 acgataggca ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc
    14101 cccttatgta tgccatcaaa atatccgaga acaacgactg aatcagatgg tgtgccaata
    14161 tctttttggt tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc
    14221 tatttctgga acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca
    14281 aaaagcactt tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact
    14341 tgtaggacat cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg
    14401 tcatactatg cttatgtatg aaaaagcaat gcaactaact cctgagaact ttaaattact
    14461 aattggtgcc gaaaaggtag aatttagaat cgaggtacac ctatgactgt aaaatttaca
    14521 aaacgagaca acttgggcaa gatgtttgaa gaatttccta aactccctga tttgaagcaa
    14581 gtcactttcc ctgatgacaa agaaaaaagc caaagcaaca aagaaaaact agatgactgc
    14641 tttccaacaa ctcccatcta gtgtgcttca gactgggcta tttttctctc catctgttag
    14701 cttggattct cagaccgttt cagctaaaga atatcttttc ccttatcaga aggaacggct
    14761 caagccattc agacaagtga agggacgaca agccaatatt tgaaaccaga taccagttct
    14821 tatagtcaat tgaaataaaa tctgaagaaa tcgagtagga aactcatatc aatttttaac
    14881 agtgttctat tccagattca tactcaatga aaattaaagt gcaaactagg aagttagccg
    14941 caggctgtac ttgagtacgg caaggtgaaa ttgacgtggt ttgaatttga ttttcgaaga
    15001 gtatcaatcc actatacata ttaaaaagta tgggtatcaa aataaaaaaa caggctctcc
    15061 gaaaactcgg aaagccttat tttaagctgt ttctagcttc ctcaccttta catttcaagg
    15121 ttcgggataa aaggttcaat gaaccttttt attttgcgat tgggtaaaca gaaacttgtt
    15181 ttttatcgcg tcctttacgt tcaaagcgta ctacgccttc aactttagcg aacaaagtat
    15241 cgtctccacc acgaccaacg tttacacctg gatagatgtg tgtaccacgt tgacggtaaa
    15301 ggattgatcc acctgttaca gtttgtccgt cagctgcttt agctccaaga cgttttgctt
    15361 gtgaatcacg tccgtttgat gtagaacctc cacctttttt gtgggcgaaa agttgcaagt
    15421 tgttaagagt catttttaac ataatgtttt cctccgtgtt agttttctgt gataactctg
    15481 gtttggacga actcagaaga gttctccgat aagtttgcca tacctaagaa aaatgattca
    15541 aagaataact gggtcatttc tctctggtgt gaaggaagat cttttggtat ttcaaccatc
    15601 agatagccac cttcatcttc atttaattct aggattggtt catagcctgc aaatttctca
    15661 atagaattga taaagttaat ggcaagcgta gaaaccgatg cacacacgac atctaagccg
    15721 tattcgccac tctcggcgtg tccagtaatt tccgcactcc tcagctcgcc atcttcggct
    15781 ctctcaaaga ctgcttgtat catgtgttct ccttaaaatt aagcgttaat tgcgttgatg
    15841 acaacttttg tatatggttg acggtgacct tgtttacggt ggctaccttt tttaggtttg
    15901 tacttgtaag taacaacttt cttttgtttt ccttgttttt caacagttcc aactacagta
    15961 gctccagcaa caagtggagt tccgacaaca gtgttttcac cacaaacaag aacaacttcg
    16021 ttaaaagtaa cttcttgacc agcttcaacg ttcaattttt caatgtaaac tgcttgacca
    16081 acttcaactt taacttgttt tccgccagtt ttgataattg cgtatgtgct cattatgcac
    16141 ctcctatgat ttttatgggt ttccccgatt tttttgtgaa gactcgccta gcatcgtggg
    16201 acaaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca caggatcgtg
    16261 catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat aacacctaaa
    16321 atcaagcttt ttcttttact tttttctgcc actaggcaaa aagcatactg agataaaaat
    16381 gctcatcata ataggaacac caagaatggt cttttcatga tagaaaatcg tcaaataggc
    16441 tgaaaagaca acgccaagga caaaactact aagcaggcta acaaatatga acccttcacg
    16501 caaaaaagga gtgtgcttag ttcggaaata atctccaaaa gctagcattg ttcgtttgat
    16561 attccctgtc ataaaggcat tattgtaggc aatacccgaa acctcaccaa aagcagttgt
    16621 caccagtccc atacagaagg ccaagggcgg cactagatag atattatcta cagtttgtgg
    16681 cacaaaacca ataattattg ataggattgc taaaggaatc aaggacagaa taggtttttc
    16741 acaattctca atttttcctt ataaatcgtt aataaaaaga ctcccatcat aaacgctatt
    16801 aaagttaaaa gcttatccct aatatccgaa acattatttt gtattagctc taccgaaaga
    16861 aagacaacat ttccagcttg tccagctaca agggtattcc ctcgaacaat aaaagtgtaa
    16921 gcatccacat atccagcaca aaatgtcaaa aaagtgctaa ccttttagac tgacgtgata
    16981 tttttcttat aggtaataac ctcattttcc ctcccattgt attttctctt agaaatattg
    17041 taccatttct ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat
    17101 aataatagac aactatttat ccaaaaatag atagaggtaa catgtttgca aacaaagcat
    17161 acgaaccttt agtaaaatca tttccatgaa actagaatag agcccctctt agcaaaaatc
    17221 attattttaa tttatttcta atcactcctt gacataaata actctcacca ataaaagact
    17281 atgtcttaaa aaaatggtat aataaaatca atacttgggc ttgatggcta tgctactaat
    17341 aacaattagg agagaaaatc aggcacttgt taacaacaag gattatcccc ttgagatgaa
    17401 aggaacttta gaaatcttat gatgaacatg caaaacatga tgcgtcaagc acaaaaactt
    17461 caaaaacaaa tggaacaaag ccaagctgaa cttgctgcta tgcaatttgt tggcaaatct
    17521 gctcaagatc ttgtccaagc gaccttaact ggagataaga aagttatcag cattgatttc
    17581 aatccagctg tcattgaccc agaggacctt gaaactcttt ctgatatgac cgttcaagcc
    17641 atcaactctg ctcttgaaca aatcgatgaa actaccaaga aaaaactggg tgctttcgct
    17701 gggaaattgc cattctaaaa acaaggagct agaacaatgc ttgtcgataa caaaggctaa
    17761 gaaaggtgca aaaattataa aaaacgcata atagcaggtg tcaaagcact caatattatg
    17821 cgttttctca tgaaaaaatt ctcttttcat actcatttaa aatcaaaaag ggaatttatc
    17881 gttttacgga catgtatatt acagatttct ataggtcgtg tatagacagg atatcatcgc
    17941 ttggaagttg tcctttttga caccaatcag taatttagtt ctcaggagtt aatggaagtg
    18001 cttttcgtac atagtttcat aactacagta tagcatagta tatcacttta tagttttcac
    18061 tattgatgaa ctgcttgagc tgctgtgatg agggtcaact tgtaaacatc atctgcatta
    18121 catccacgag aaagatcatt aactggcttg tttaaacctt gcaaaacagg tcctacagcc
    18181 gcaaagccac ccaggcgttc agccatcttg taaccgatat ttcctgcctc gatacctggg
    18241 aagatgaaga catttgcttg accagctact gtacttcccg gagctttcag agctgcagtt
    18301 tcgggaacaa aggccgcatc aaattgcaac tcaccatcga tttcaaggtc aggacgcaag
    18361 tcgtgagcaa ttttagttgc ttcaacgacc ttatcaacgc tttcaccaaa ccctgaacct
    18421 ttagtagaat agctcaacat ggcaatttta ggttcgatgc caaacatctt agctgtgatt
    18481 gctgagttga tggcaatttc agccaaggct tctgcatctg gattgatatt aatggcacag
    18541 tctccaaata ggtaacgttc cgtaccacga accatgagga aggctcctga agtacgagtt
    18601 acatttggac gagttttgat gatttgtaga gctgggcgaa ctgttgaagc tgttgagtga
    18661 atcgctcctg acaccattcc atcaaccaag cccaagtaaa ccagcatcac accaaagtag
    18721 ttgacatctt caaccaaaac cttgcgtaca tcttcttcag tcattttgcc cttgcgacgc
    18781 tccaccaagg cagaaaccat ttcttcaaat tgaggataat gttgagggtc gatgacctca
    18841 taaccatcca tgattccttc aatttcaaga taaattttaa ttttttcagg atttccaagc
    18901 aaaacaggaa tcacttctgt ttcttttact aagcgttttg ttgcttgaag aatacgaggc
    18961 tcttcccctt cagggagaac gatacgagca tttttaccaa caaggttggc tttgagactt
    19021 tcaaaaactt ccatgagttt tctcctttaa gataataatt atactctgag acagttttta
    19081 tagagtatta gttgataact gggtaataag gttactgaaa tcatccggca agggactttc
    19141 taactgcaag tcttgctcta aaaatggatg ataaaaggat aggtaatggc aatgcagagc
    19201 ctgacgttga ataccatctt ccagactacc accatacaaa tcatctccca gcaaaggaaa
    19261 accgatatga gaaaaatgga ctcggatttg atgggttcga ccagtgtgca ggtgaatata
    19321 aaccaagtga atatttccat aagaagctac aatcttgtat gaagtatggg catactttcc
    19381 gcctttagcc actcgtctgg taataatgga atcttcatca cgcgcaattg gagcaataat
    19441 ttccccttct ggctccaaat gtccatctcc cttaaccaaa gcaaagtagc gtttctcgat
    19501 agattttttc tgcaactgct tgtctaatcg tgtatgggca taaccgtgct tggcaaagag
    19561 catcaagcca gaagtgtccc tatctagtct ggtaacaatg tgaacctgct gattttcata
    19621 attttgcttg acatagtaac ccttgataaa attggcaatg gtattagagt gattgacact
    19681 aggaatagaa gccactccat agggtttatt caagactaga aagtggtcat cctcatagag
    19741 aatatctaat ggatgctcaa tagcctccaa ggtttcaaag ccttcctcag cgggaatgtc
    19801 aatggtaacg tagtctccaa cgtccaatag atacgttgca ttttgcggtt gattattgac
    19861 cagaatagct ccacctcgaa acttaatctt ggccagcaat cccttagaaa cctcgtgctt
    19921 ttttaagaag gtcttaacct tgacatgttc atctgcgata aattcaaacc tcattcatcc
    19981 acctcaccga taaaggcatc cttaacacgg ttccagaaac tggtatggct aggagtcgcg
    20041 acaaagtgaa tcttatgatg gtcgatttga tactcaatac gctcaatatt acggaaagaa
    20101 taaacgctat tgtcaaccga aatagtatga taatcgtttc ttgttggaat aagttcaatc
    20161 ttatccttct taggcacaat aatggaagag cccagtgttc gatagacacg attattaagg
    20221 ctggcaattt ccgttaattg caaagcttca atggtagggt gtaaaacagc accgccaaga
    20281 gacttgttat aggcagtact accagtcggt gtcgaaactg ttagcccgtc tccacgaaaa
    20341 cgttcaaagg gaacaccatt tattacaata tctgccacca tggttcgatc agacctgcgg
    20401 atgctggctt cgttgagtgc tctgaaaatc ttaacttcac cattttcaag aaagaccttc
    20461 acattcagaa cagggtaaga aacccttgcc ccagtatcta gctgcaaatt agtcactagc
    20521 ttgtccaact caaaatcacg ataatctgta tagaagccca aatgtccagt atgaagaccg
    20581 ataaagcgga ccttgtcaag ctgattttcg tacttatgaa aggccgacaa gagcatacca
    20641 tccccgccaa tggaaatgac aatatccgga ttggtatcat tgagtataaa ctgatttctc
    20701 ttcaaacgat ctcgcaattc atacaaaacc ctttgactct gcggttttct attggctatc
    20761 agatcaattc gtttacctgt attcttcatc tgtatcgtca ctgtttccta caccgtcatt
    20821 taattttcta ctcaaaggat caaaaagtgc ctgggcttct tggatatcat cacgaatttc
    20881 acccatttct tcatccaact gatgggcgat tctagctgta atttccagtc gcttcttaat
    20941 ctcatctggg aaatcccctt ggtacttgta gttgagagaa tgttctatcg ttgcccagaa
    21001 attcatggcc aaagtacgaa tttgaatttc tgccaaaata gtcttagctc cattgatggt
    21061 atcaaccgta tattctacta ccacatgata ggaacgatag cctgatgctt ttctatgagt
    21121 aatgtaatct cgctcctgta tgattcgcat atcctgacgc ttgtgcaaaa tatccactac
    21181 ttccttgacg tcatctacaa actgaaccat cacacgtaag ccagcaatat cctgcaaatc
    21241 gtgttccaag gtcgcataag taatgccacg acgagccatt ttttctttga tgctctcaat
    21301 tggcttgact cgaccggtca caaactcaat tggagaatgc ttattttgct tacgatattg
    21361 cttacgaata ccacgaagtt taatctttaa ctcaccaaca gcttgaatgt aaggatctag
    21421 aaattcttcc cattctaagg tcatatattc tcccttgttc tcatattatc cgtcaaaaat
    21481 atctttgatt ttttctccag attcatatac aataaataca atgcttatta taccataaat
    21541 ccgctttcaa cgataaaaaa aggtaagaaa aatgaaacat ttagaaattg aattgaaaac
    21601 actattgaaa aaagatgaat acaatcgtct aaaagaccag ttcacaggtg tcactcctgt
    21661 tcttcaaaca aattactaca tcgacacgcc tgattttgaa ctgcgagaaa agaaagtcgc
    21721 tatgcgcatt cgaacctttg aagactgggc tgagttgaca ctcaaagtcc cgcagagtgt
    21781 tggaaacatg gaatacaacc aaaaattgca actaaaagat gctgagaact atctgagtaa
    21841 ggaagaactt cctcaagggc tagtactgga tgaattggcg aaacatggta tccaaagtaa
    21901 gaactggcag gttcttggtt gtctaacaac gcttcgctat gaaatgaaaa cagctattgg
    21961 tctcatggca ctggatcaga gccgatactt tgatatgaca gattacgaat tggagcttga
    22021 agtggaaaat catgagcaag gcaaacagga tttccgacaa tttttagaga aaaatcagat
    22081 ttcctaccaa aaagctcctt caaaattggt tcgatttgtc aaaagtatga aaaatagctg
    22141 aaataatctc cattttttgg taaaatagaa aagataaaaa tacacaaacc ccagttcata
    22201 tatgtaaggt aaatataact aggatttata aagtttacag aggacggtct ataatgtcag
    22261 atagaaaaaa catgaaactt ttcgcactca actctaacca agagattgca caaaaaattg
    22321 cccaagctgt tggtgtccca cttggaaaac tatcatcacg tcaattttca gacggagaaa
    22381 tccaagtaaa tatcgaagaa agtgtccgtg gttatgatgt ttacatcatc caatcaacaa
    22441 gtttccctgt caacaaccac ctaatggaat tgttaatcat ggtcgatgct tgtgtgcgtg
    22501 caagtgccca cagtatcaac gttgtccttc catattttgg ctatgcacgt caagaccgca
    22561 ttgcttgtcc tcgtgagcca cttacagcaa aactagttgc caatatgctg gttaaggctg
    22621 gagttgatcg tatcctgact cttgatttgc atgccgttca ggttcaaggt ttctttgata
    22681 ttccagtgga taatcttttc actgttcccc tattcgcaaa acattactgc gataaaggat
    22741 tgcttggttc agatgttgtt gtcgttagcc ctaaaaattc aggtgtcaaa cgtgcgcgta
    22801 gcctggctga atatcttgat gctcctatcg ccattatcga ctaccctcaa gacgatgcaa
    22861 ctcgtaacga aggttatatt attggtgatg ttgaaggtaa gaaagctatc ttgattgatg
    22921 atattttaaa tacaggacgt accttctctg aagcttctaa aatcgttgaa cgtgaaggag
    22981 ctacagaaat ttatgctgtt tctagccacg gtctcttcgt cgagggagct gctgagcttc
    23041 ttgacaatac taatattaaa gaaattcttg tgactgattc agtagcaaca aaagaaaaaa
    23101 ctcctaaaaa tgtatgctac atcactgcta gtgagttaat tggtgatgct atcgtccgta
    23161 ttcacgaaag aaaaccagtc agcccactct ttgcctacaa taaaaagaaa taaggtgatt
    23221 ctttgattta tttggacaat gctgcaacga ctcctatgtc agcagttgct atttcagcta
    23281 tgaccaaggt tatgcaagaa acccacggaa atccttctag tattcatggt catggtcgtc
    23341 aagctggcaa actcttgcga gaagcccgtc aggaactagc ccagttacta aggacaaaac
    23401 ctcaacatat ctttttcact tctggtggga ctgaaggcaa taatactacc atcattggct
    23461 actgtcttcg tcaccaagaa caaggaaaac atatcatcac aactgccatc gagcaccatg
    23521 ctgtccttga aacaattgat tacttggttc aacactttgg gtttgaagca accattatcc
    23581 agccagaaaa tcaagaaatc acagcccagc aaattcaaaa ggctttacgt gacgatacga
    23641 ttttggtttc tactatgttt gccaataatg agacaggaaa cctacttccc atcgctgaaa
    23701 ttggccaaat actcaagcaa caccctgctg cctatcatgt tgatgcagtt caggctattg
    23761 gtaaaatccc aattcattca gaagaattgg gcattgattt tctcactgct tctgcccaca
    23821 aattccatgg tcctaaggga atcggttttc tctacgcatc tagcatggac tttgattcct
    23881 atctacatgg cggagatcag gaacagaaaa aacgtgcagg aactgaaaat ctgcctgcca
    23941 tcgtaggcat ggttgcagcc ctaaaagaag acctagaaaa acaagaagaa cattttcaac
    24001 atgtacaaaa tctagaaact gcctttctgg cagagctgga gggcattcag tattacttga
    24061 atagaggaaa acatcatctc ccttatgttc tcaatattgg atttcctggt cagaaaaatg
    24121 acctcttact ccttcggcta gatttagctg gaatttcaat ctctactggc tcagcctgta
    24181 ctgcaggcgt tgtccaatcc agccatgttc ttgaagccat gtatggcgca aattcagaac
    24241 gcttgaagga atcccttcgc atcagtttgt cgccacaaaa taccgttgaa gacctacaaa
    24301 ccctcgcaaa aaccttaaaa gaaattatcg gaggttagcc atatggcatt tgaaaaaatc
    24361 attcagttaa aaaattgtcg ttacgattac actcttagcc cttctgttaa aaaattcacc
    24421 ctcaaagata acaccttttt tgaaactaag gttggtaact atgaactgac tcgccttttg
    24481 gaaaaagtgc caaacagcgg tgaaggcttc caactcaaaa tcatcattaa caaggaactt
    24541 acaggggcta aaatcaatat cactgacaag tttggccttc gtctagttga tattttcaaa
    24601 tcagaagacc accatattca tcaggaaaaa ttctacttcc tcatggatag cttggtagaa
    24661 cgtggtgtct ttacaaaatc ggaaagatag agccaaaatg tttgaactga cctataagga
    24721 ctgctatcat gtagagcgta ctctcaagta tgaggatcat gaggctctca tgttgacttt
    24781 gtcaggatgt gtaaccttac cagatacact ttatgtgact tctctgactt ttaggggcaa
    24841 aaaagtttat caggggctgg tcggagacct ctaccgtttt ctatctcatg cagatttttt
    24901 acatcaaaac taagattttt cttagttttt tcttattttt gttgattttt tcacaatgtt
    24961 tctataaaat agaagaatag aaaggttgtg attttgtgaa agataaacag tttgctattc
    25021 caaaagctac agcaaaaaga ctctctctct actatcgaat ttttaagaga tttcatgcag
    25081 aaaagattga acgtgccaac tctaagcaaa ttgcagaggc tatcggtatt gattcagcga
    25141 ccgtacgtcg tgatttttcc tattttggtg aacttggtcg tcgtggtttt ggctatgatg
    25201 tcaaaaaact aatgacattt tttgccgatt tgctcaatga caactctatt accaatgtca
    25261 tgctggttgg tattggaaat atgggccatg cccttctcca ctaccgcttc cacgaacgta
    25321 acaagatgaa gattatcatg gcctttgacc tagacgacca tcctgaagtc ggtacccaaa
    25381 ctcctgacgg gattcccatt tacgggattt ctcagatcaa ggataaaatc aaggatgctg
    25441 atgtgaagac tgctatccta actgttccca gcgtcaagtc acaagaggtt gctaatctct
    25501 tggttgatgc tggtgtgaaa ggaattctca gtttttcacc agtccatctg catttaccaa
    25561 aagacgtggt cgttcagtat gtcgatttga caagtgaact ccaaaccctc ctctacttca
    25621 tgcgaaaaga ggattagaaa gcgaaaatca ttttatgaaa aaaccagtta ttgggattac
    25681 aggaaacgaa aaaactcatc cagatgatga catcatgatg agctacgcag caaaaggctt
    25741 tgttgaaggc gttaaagatg ctggagggat tcccatcatc ctaccgattg gtgatcaaga
    25801 aatggcctgc cactatatca gtttgattga caagctcatc ttgacaggtg ggcaaaatgt
    25861 cgatccaaaa ttctatggcg aacccaaaac cattgatagc gatgattatc accttcaaag
    25921 agatatcttc gaactggccc tcatcaagga agctattaaa cagaaaaagc ccattttctc
    25981 tgtctgccgt ggtacccaac tctttaacgt tgccatgggt ggaactttgt accaagatat
    26041 cgaagaccat tggcaggatt cttctgttga gtacacaact caacgcttgg taacagaacc
    26101 agataccgtt ctccaagaaa tctatggaga aatctctcat atcaactcct tccaccacca
    26161 gagcatcaag gacttagcac caaatttaaa agttgtggct catgatccta aagatggtat
    26221 cattgaggct gtcatgagta cggatgatgt cgcctttctc ggtgtccaat ggcatccaga
    26281 acttcttttt gaaaatcgtc ccaaagataa gaaactcttt gactatgtcg ttaatgaact
    26341 ttagattaaa tctgtctttt cacgataact aaagtaatta gaatgagaga caatcaaatg
    26401 gtccaagaga acaatcccca tcagttcgca ggcttcttta acaagtttag tgacatgatc
    26461 atcattttgg ctaggcgcta ccgctcctga aggatgattg tggaccaaga taagagaagt
    26521 cgccatatgc ttgattgcat agtgaagaat ctctcgcggt tcagcgatac tacgagttac
    26581 agaaccgata aaaatggtct gctgatggat gatttgattt tgagtattga gatagagtgc
    26641 caccaggtgc tcttgttttt tatcccctaa ttcctgctgc atcttcttgg ccaacttttg
    26701 actgctgaga atactttcca tttcaagagt ctcgtgtttg tgaatacgat gccccagttc
    26761 aatcatagct tgtaattcta tggccttaac acgcccaata ccagacaaac tctgcaattc
    26821 ctgcagggtc atttttttca aatccgttag gcttgaaaga ttgttcaaga ctttttgggc
    26881 aatttcaaaa acgctagctt gacgtgttcc tgtcctgagt aaaatagcta gcaactcttg
    26941 gttactaagc gcttcaactc cttccttggc cagcctttct cttggtaata gtgaatcttc
    27001 ttggaatgaa atactgtaca taaaaatcct cctcacttta ttattcgtga gaaggatgga
    27061 aaattagatt tttttctcaa ttggagccac actggctaaa agttttttca aacctacttc
    27121 tgggaaattg attttcaatt cctgcctagc accgctacct gaaacttcca gaacggttcc
    27181 ctctccccat ttcttgtgga gagcaatatc accaatggac caatttgcct cgctagatgc
    27241 tggttttgcg ccagctgtaa attgaccaaa tggaagaccg cttgactgga ttgattttgg
    27301 ggcagcaccg cgtttacggt cttgaagagc ctgagccaaa ctcatacctt gaccaaagga
    27361 aatactacca ctgctatatg atgccttaaa gcttgtattt gcaggacgag ccagaccttg
    27421 atactcaagc aagtctgaac tgatttcgtt aataaaacga gtcggacggt tataattggt
    27481 acgaccaaaa agcaagcgtg agttggcatt ggtcagatag agaattttct ctgcacgcgt
    27541 gatacctaca taggctagac ggcgctcttc ttctaattca tctggatctt cagtcgcacg
    27601 actaagtgga aagacatttt cttccatccc aatcaaaaag acaactggaa attcgagacc
    27661 tttggcagca tgcagggtca tcaaggtcac ttctgatgtc tcctgactac ctgaatctgt
    27721 gtcggcaatc aaagccaagt catttaagaa acgactcagt ttgtccagac cagtttcctc
    27781 ttctgtcaca tccgtggtgt catcaaagtt cttcgtaaca gaaagaaact cttcgatatt
    27841 ttcaacccgt gccttgcttt ctaaagtcgc ttgggcgtta agaatatcga cataacctgt
    27901 tttttctagg acggactcaa ccaactctgt aatgcttaag tggtctagct gctcccgcaa
    27961 atcaagcatc atattggcaa aatcccagat agattgggct gccttaccct tgataccaga
    28021 caacataata ttagcagaag catccagcat agacatattt tgcaaatttg caaaatcacg
    28081 gattttctca actgtaccta gaccaattcc acgtttaggc tcgttgataa tacgctcaaa
    28141 actaatattg tcactcaaat tagcaataag gttgagataa gcaataatat cgcgaatttc
    28201 cttacggctg tagaatttgg ttccgccaac catggtataa ggaatgttag acttgagcag
    28261 ggcttcctca attgtacggg actgggcatt agtccgatag agaactgcaa aatccttatg
    28321 aaggaagttt tgactgcgac taagttcatc gatggttctg gctacaaata cagcctcatc
    28381 cagctcatca tcggcacgat agtaaacgat ttgctcccca tcagcgtttt gagtccagag
    28441 atttttagga cggcgatttt tattattttt aataacctcg ttggccgctt ggagaatgat
    28501 tttggttgag cggtaatttt cctccaacaa aacaaccttg gctttggggt aatccttttc
    28561 aaagtccaag atattctgca tatcagcacc acgccaaccg tagatagact ggtccgcatc
    28621 cccaaccaca cagatatttt taaaacggga agccaagagt ttgaccaatt ggtactgagc
    28681 gtggttggta tcttggtact catcaacgtg gatgtattgg aatttttgct ggtagtaggt
    28741 caaaacatca ggattttgat caaagagacg caaggtcagc ataatcaaat catcaaagtc
    28801 aacggattcg gactgacgaa gttctttttg ataggctgta taacactggg ccacaatttg
    28861 cgtatacata tcgccagctt gggcagcata agcaacatca tcaatcaaat cattcttagc
    28921 attggaaatg gtccccaaaa tagttcgttc attccatttt ttaggatcca agttcaactg
    28981 ttttagaata cgtttcatga gcgttcgctg ttcaccagga tccacaattg taaaattacg
    29041 attgtagcca atatggtccg catctcgacg caaaatacgc acacacatgg agtggaaggt
    29101 cgcaatcaga cagtcctgag tagctggatt gaggctataa gcacgctctt tcatctcacg
    29161 cgcagccttg ttggtaaagg taatggccaa gatattccaa ggattgacca gcttttcatc
    29221 aatcaaataa gcgatacggt gggtcaaaac acgagtcttt ccagaaccag cccctgccat
    29281 gattagcaag ggaccttctg tcgtttgcac cgcctcagcc tgacggtcat tcattccatt
    29341 taataatgcg ttcatcttct cttccttact cttgaagtca atatttctat tatatcagaa
    29401 atcagggaaa atagaaactt tacggggagt agcaaaatat agtggattga aactagaata
    29461 ctacactgtg ggtttctaaa acactcgact ttttcaccca attttttcat aaactagctc
    29521 aatacctca
//
LOCUS       DAVDFK010000023        29056 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.23, whole genome shotgun sequence.
ACCESSION   DAVDFK010000023 DAVDFK010000000
VERSION     DAVDFK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.23"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..82
                     /locus_tag="VUR04_001292"
     CDS             <1..82
                     /locus_tag="VUR04_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5341184.1"
                     /translation="LELTEETSMLSHLKKEVEIYYQAKER"
     gene            complement(371..1762)
                     /gene="argH"
                     /locus_tag="VUR04_001293"
     CDS             complement(371..1762)
                     /gene="argH"
                     /locus_tag="VUR04_001293"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET5341185.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLTGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAHHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYRHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(1791..2987)
                     /locus_tag="VUR04_001294"
     CDS             complement(1791..2987)
                     /locus_tag="VUR04_001294"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET5341186.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVSVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQIGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(3004..3810)
                     /locus_tag="VUR04_001295"
     CDS             complement(3004..3810)
                     /locus_tag="VUR04_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5341187.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(4017..4658)
                     /locus_tag="VUR04_001296"
     CDS             complement(4017..4658)
                     /locus_tag="VUR04_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341188.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4655..6763)
                     /locus_tag="VUR04_001297"
     CDS             complement(4655..6763)
                     /locus_tag="VUR04_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5341189.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKGYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPNTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6818..7111)
                     /locus_tag="VUR04_001298"
     CDS             complement(6818..7111)
                     /locus_tag="VUR04_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5341190.1"
                     /translation="MIGEINHEKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            7518..7838
                     /locus_tag="VUR04_001299"
     CDS             7518..7838
                     /locus_tag="VUR04_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5341191.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLVICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(7890..8477)
                     /locus_tag="VUR04_001300"
     CDS             complement(7890..8477)
                     /locus_tag="VUR04_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET5341192.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8719..9390
                     /gene="sdaAB"
                     /locus_tag="VUR04_001301"
     CDS             8719..9390
                     /gene="sdaAB"
                     /locus_tag="VUR04_001301"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET5341193.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            9399..10271
                     /gene="sdaAA"
                     /locus_tag="VUR04_001302"
     CDS             9399..10271
                     /gene="sdaAA"
                     /locus_tag="VUR04_001302"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET5341194.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            10293..10925
                     /locus_tag="VUR04_001303"
     CDS             10293..10925
                     /locus_tag="VUR04_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5341195.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(11227..13077)
                     /locus_tag="VUR04_001304"
     CDS             complement(11227..13077)
                     /locus_tag="VUR04_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET5341196.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(13119..14276)
                     /locus_tag="VUR04_001305"
     CDS             complement(13119..14276)
                     /locus_tag="VUR04_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5341197.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            14334..15500
                     /locus_tag="VUR04_001306"
     CDS             14334..15500
                     /locus_tag="VUR04_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET5341198.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15638..15964
                     /locus_tag="VUR04_001307"
     CDS             15638..15964
                     /locus_tag="VUR04_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET5341199.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            15951..16544
                     /locus_tag="VUR04_001308"
     CDS             15951..16544
                     /locus_tag="VUR04_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET5341200.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            16537..17448
                     /locus_tag="VUR04_001309"
     CDS             16537..17448
                     /locus_tag="VUR04_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET5341201.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            17510..18574
                     /locus_tag="VUR04_001310"
     CDS             17510..18574
                     /locus_tag="VUR04_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341202.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEETDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISTLVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(18750..19610)
                     /locus_tag="VUR04_001311"
     CDS             complement(18750..19610)
                     /locus_tag="VUR04_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET5341203.1"
                     /translation="MAKTFFIPNKQSILGEQEILTAKSILALVDGLESHSYDAVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWRIIKLFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAHLTDNAVRFTICQGIFNPIFFSHEDLKSFLEEDGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(19885..20871)
                     /locus_tag="VUR04_001312"
     CDS             complement(19885..20871)
                     /locus_tag="VUR04_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET5341204.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(21143..22618)
                     /locus_tag="VUR04_001313"
     CDS             complement(21143..22618)
                     /locus_tag="VUR04_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET5341205.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(22702..23625)
                     /locus_tag="VUR04_001314"
     CDS             complement(22702..23625)
                     /locus_tag="VUR04_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5341206.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(23639..24568)
                     /locus_tag="VUR04_001315"
     CDS             complement(23639..24568)
                     /locus_tag="VUR04_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5341207.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(25058..25237)
                     /locus_tag="VUR04_001316"
     CDS             complement(25058..25237)
                     /locus_tag="VUR04_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341208.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKD"
     gene            complement(25663..25818)
                     /locus_tag="VUR04_001317"
                     /pseudo
     CDS             complement(25663..25818)
                     /locus_tag="VUR04_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(26004..26615)
                     /gene="rpsD"
                     /locus_tag="VUR04_001318"
     CDS             complement(26004..26615)
                     /gene="rpsD"
                     /locus_tag="VUR04_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET5341209.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(26810..27862)
                     /locus_tag="VUR04_001319"
     CDS             complement(26810..27862)
                     /locus_tag="VUR04_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5341210.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(27859..28557)
                     /locus_tag="VUR04_001320"
     CDS             complement(27859..28557)
                     /locus_tag="VUR04_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341211.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(28724..>29056)
                     /locus_tag="VUR04_001321"
     CDS             complement(28724..>29056)
                     /locus_tag="VUR04_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5341212.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         8641 a         6369 c         5271 g         8775 t
ORIGIN      
        1 cctagagctg accgaggaaa cttctatgct gtctcatctc aaaaaagaag tagagatcta
       61 ttaccaagcg aaggaaagat aaaaaagccg agggatttcc tcgactcttt acatattatt
      121 tgttcgttag ttcttaatac cagccattgt taaaccagaa gtttttagct ctgccaagcc
      181 acatagtgtg tttactacta tgtgtccatg tcaccatgaa tcgccgaacg atttaacgag
      241 aaagtatgac ttttacgttt atcccaactc aattatgaca tttttttcaa aagtcaatat
      301 atctcacttt ttcaacgaca agaaagaggc tgccaatcga ccaacctctt attctgaacc
      361 catcactcca tcacttttta gcttcattcg ctttcttagc gactgcaatc tggtattcga
      421 cttggtcaaa ccctgtgcct cccaaggaat ttcgtctttg aacagcagtt ttaggttgca
      481 agtagacata gatatcctcg gtaatgagag aatgataggt ttgtaattcc tccaaagtcc
      541 aatcttgaag atttttagca gacttgatag agtctagcac taatcttccc acaacctcat
      601 gagcttctct aaatggcaag cctttccctg ccaaataatc tgccaactca gttgcatttg
      661 aaaagtcctt ctctgttgat tcttgcattt tttccttgtt tacctgcaaa ctagataaca
      721 tacctgccaa cacatcgagg gaatttaaaa tcgtttcgac cgtatcaaac attccttcct
      781 tatcttcttg caaatcctta ttataagcta aaggcaagga cttcatgact gtcaacagtc
      841 caaacaaatg cctataaact ctgccagtct ttcctcgaat caactcagcc atatctggat
      901 ttttcttttg gggcataata gaggaacctg ttgtaaacgt atctgacaag gtaatgaatt
      961 ggtactcaaa actacaccaa ttgatcattt cttcgcaaaa acgactcata tgcatcatga
     1021 gtatgctggc atttgataga aattctaaga taaaatcgcg gtcactaaca gcatccaaag
     1081 aatttgtata aggttgctta aactccagca aatcgctaga caattggcga tcaatgggga
     1141 aagtcgttcc tgccaaagct gccgcaccta aagggcatag gtctgtatgc ttctggttaa
     1201 attcaaaacg ttcactgtct ctttgaaaca tattgtagta agccatcagg tggtgggcaa
     1261 aactaatagg ctgggcatgt tgcagatggg tatagcccgg catgatcgtc gccacatgat
     1321 tttccgccaa gtctaataaa acacccgtaa gatgagccag tttatctagg acatagccta
     1381 gttgttcctt gagatacaag tgcatatctg tcgcaacttg gtcatttcga gaacgagccg
     1441 tatgtaactt ccctgcaagg ggaccaattt tttctgtcag caacacttcc atattcatat
     1501 gaatatcttc gtttgcgata tcaaagtcaa gttgacctgc ctctagctct tctaaaagct
     1561 ctttcaagcc tacttgaatc ttttctgact cctccaaact caaaatgccc gtctgaccca
     1621 acatctgaac gtgggctaaa gaaccaatca catcaaattt agctaatttc tggtcaaaag
     1681 atatactcgc accaaagcgc tctacccagt cttcgacagt accttcaaag cgaccacccc
     1741 ataattttgt attcttagcc atatcacatc cacctctcta tccaatcgtc ctatttggcg
     1801 cttttttgaa cctcagaatg aaccttggtt ggaagtcccc ataacttaat aaagccaaca
     1861 gccgcatctt ggtcaaaggt atctgcacta gtatacgtcg ccaaattttc atcgtaaaga
     1921 gaatttggtg atttccgagc cacgacctga gcgctcccct tatacagttt gacttttgca
     1981 gtcccattga caactttttg agtctcttta atataagcaa tcaaggcttg tgtagccgaa
     2041 ctaaaccaca aagcattata aatgagattt gataattcat tttctatgat tggtttaaaa
     2101 tgagccactt ctctcacaag cgtcaagtcc tcaatttcct tatgagctgt cagcagggtc
     2161 actgcacctg gacactcata gatttctctt gatttaatcc caaccaagcg attttccacg
     2221 tggtcaatcc gtccaacccc atgttttcca gctatttcat tgagtttttg aatcaaatct
     2281 gccaatttta acacttctcc attgagggaa actggaacac cttcactaaa ctcaatctca
     2341 atgtattctg gcatatctgg agcttgctct ggagaagttg tgatgccaaa ggcttcttct
     2401 ggagcctgat tccatggatt ttccaaaata ccacactcat tggcacgtcc ccaaagattt
     2461 tggtcgacag agtagggatt gtcaaggtca gcaggaacag gcaccccatt ttccttggca
     2521 taataaattt cttcctcccg agaccatttc cattcacgaa ctggagcaat cacttttaaa
     2581 ttgagatcca aggctgcaat cgatacttca aaacgtactt ggtcattccc cttaccggta
     2641 caaccatgag caattgtagt cgctcctatc tgatgcgcta tttcaaccaa ttttttagaa
     2701 atcagagggc ggctcaaggc agataccaag ggatactttt gttcataata ggcatgtgac
     2761 tgatgagcca ctagcacata atctgtagca aattcgtcct taacatcaat gacataagat
     2821 tctactgccc caaccttaag agccttatca tggatgaaat ctaagtcttt cccttcaccc
     2881 acatccatac aaactgaaac aacatcatag tctttcttta accaggtaat agcaactgat
     2941 gtgtccaaac cgccagaata ggccaaaatt actttttctt tactcatgtt cttttccttc
     3001 tttctatttt tcaatggatg ctttaaaggc atcctcaatg agtttgtcta attccccaga
     3061 ctccttcaac ttttgaatgg ttttatcgac tgcctctttc aattccttgc tatctttttt
     3121 catggctacc gcgtaggaat catcttgctc tttttcaaaa ttgaggtctg cgattgctaa
     3181 atcaggatta ttttccacaa atcccttgga aacaggttct tcaaagataa cggcatccac
     3241 ttgtcctgat tttaaatctg tgattaaatt cccattttta ggcagagata cgagggaaga
     3301 attttgtagc aaatctttcg ccatcgtctc ttgaatcgaa cctttctgcg ctccgacctt
     3361 tttctgcgcc aagtcgttta cagactgata agtagtcaag tcagattttt tgacaatgag
     3421 tttatttttt gcagtatagt agggagttga aaaatcaaac accttgctcc gttcatctgt
     3481 cttagaaaca cctgatatgg caaggtcagc ttttcctgat tgaacgctag ccagtacatt
     3541 gtcaaaactc ataggagata gttccaattc gacacctagt tctgttgcga tagccttggc
     3601 taattcgata tctgaaccca caatctgatt tttcccatca accacttttt gatattcaaa
     3661 tggagcaaaa tctggattga gggctacaac caattttcct ttggacttga tggcttcaat
     3721 tccagccgat tgattgttac tacaagcaaa tagtaggggg agcatcacta aaccaaacat
     3781 cgtcatcaac accttcttca tcttattcat aacaaagcct cctttatgtt tattcttttt
     3841 tattgtataa ataatactcc tatactcatc ctttgtcaag cctaaattga aaaaattttc
     3901 aatttgaaac aaaaaaaacc tagaaatact acataaaatg tcattcctag gcgtatttat
     3961 gctatttttc tctggaaaac atgagtattc agccagtcaa aaggagctga atgaactcat
     4021 tttccctcgc ccaattcaat gacacgatga cattgttggg ctacataagc atcgtgggtc
     4081 acaataatga ctgttttccc ttctcgattc atctctaaga gaaacttcaa gaccaaatct
     4141 ctattttcag gatccagcga acctgtaggt tcatcggcta aaatcagctg gctgggtttt
     4201 aagatggctc tagcaactgc aattcgttgt tgttcgcccc cagacaactc ggagaccctt
     4261 tgatgcaaag tagctgacaa acctactctc tctaaaatct cttccacctt tttgagcttg
     4321 tctttcttag gcaatttcac atatttcagc gccagcatga gattgtactc gaccgtttca
     4381 tcatcaatca gggcaaaatt ttgaaacaga taagagatat gttcacggat tattgtttgc
     4441 gacttagcag aattaaccgc tagatttgtc tgaccaaaaa tctcataccg tccgctataa
     4501 tcaccatcta tcaaacccaa taaatttaac aaggtcgact tcccactacc actcttacca
     4561 acaatagcta ccaaatcccc ctgatcaatc ctgagagata agttatccaa aatcactttt
     4621 cccccaatgg ttttggtaat atttttcaac tcaatcataa gatgccccct ttcaataact
     4681 ctactagact tcttttctcc atcctagaag ctaagcctag cacaaatagt atatccagac
     4741 atgtaaaacc tgcaaacagt agaagtggta agaacgcatg ggcaaagaaa atcaagacta
     4801 gaagagggaa actatagccc agcaagagca gaacgaggag aggacggtag cgatcgacca
     4861 gtttccaccc cataaacttc ttggtaatga tatccctgcg cttcaataag aaagttgtta
     4921 ctagtaagaa gtaggaaatc atcatgctaa ggagaccaaa caaagcaaag agtaggttaa
     4981 aattccgaac agcatctcga taagaatcca ctttctcttg ttgaatggct tgaatagatg
     5041 aaaattttaa ataatttcca tctgacaatt tctcaactaa ctctgtaatc tctttttgat
     5101 gttgaaccgt attttcaatt ttaatcggat tatttaagcc agttgttgac agggaggctt
     5161 tctcatccca catcatatca gaatcattga ccaagctaat aattggattg gagagatttt
     5221 cctttcgctt atcactatat gggaaaaatg accaatctcc ttcataatag gcaatctcga
     5281 catccatctc ctctatcgtt cgtttttgct gctcttcata cttcatcgaa tgaaaggcaa
     5341 ttaacttccc caagagctga tttttatctt cttcaccttt cgtacttgct ggcatcaaaa
     5401 taactttttt aataccggta tttggtagct tgaatccctt gctctttaga aaattgcgat
     5461 tggcatagta aacatccacc gtatctgtta actgatattg ctgaatctgt tctgattgga
     5521 caaaattttt tacaggaaga ctgctactct gcacatagcc cgcctgcgtt ttttctacca
     5581 aatcctgata aaatcgatag aaataatctg tagatttccc tgaccctgct agctcttctt
     5641 gccacagatt atcattgagt ttgaaggttt ctaaggtcag gtaattacct tgacttaccc
     5701 actgttgctg ataagcaagt tctttgtttt cttgttctaa acttctgccc accccaatca
     5761 gtaaggccgt cagtaaaata gttgtcccta ttttcatcac ataattgaag ataagaccaa
     5821 atttgaaaga tgaaaaacct ttcagcagag agctgattgt cattttttgg attaagaggt
     5881 aagtcaacca actgataaag agataaagct gcaacagcaa aaaatgagac aaccacagca
     5941 taggaaacaa atcttttggc ttataatcaa gcaagaaaaa cacgcctaga ttgatcacaa
     6001 gagccccacc taggaggagg taaaggttgc cttttacaac atcagctaaa acagccctat
     6061 cttgaaaacc aagtaatttt tgtaccccaa ctcttttcat ctccatcatc ggttgataca
     6121 ctgtcactaa cacaagaagc aaaatagcca agacaaaaac aatggcagat aaaagcaaat
     6181 ctcgatttat gacttccact gcacttttgt aggtcggctc tagcaaggta gcctggtcta
     6241 tcttgaaaaa atcgctccat ttctgtacaa tcctatcctt gtccatctct tgtgtagaag
     6301 ttatcgtata gcgaccattt aaactacgag atgtatcctt gatataggtt tgaaaagtca
     6361 taagctgaat aggtttggct tttagaaagg tcggaatcgt accaagttta ttggaaattt
     6421 ctttattact atagactcct tcaccatctg tggtaaaatc aagagaagaa atcccaaact
     6481 cttggtaggg gaaggtatct ttatcaaaaa caccagactt gaccacctca tcaccactgt
     6541 ctgttttgat gatggagact ttatacccct ttgatacatc ctcaaaaaat cgaagaacag
     6601 acgctgcagg ttcgttaata tctttcaaat acaaatccaa agaatctaca gtctttccca
     6661 tttcttgaat ccgaaccact tctcgtgtat agtttacatt aaaaacaaaa aaagtggtac
     6721 acagaagcag gagtaacata caaagatgac tgattttttt catagagata cctcccgtga
     6781 agaaactccc tctccaaaag gggagggaga attttaatta aaatccatag aaatattcca
     6841 ttcccgttgg tgggaatttg aagattgaag cccgagccca tgcctcagct tctgcacgat
     6901 ccttagagaa tttatttcca tctttaacag ttgctgtatg agagcgagta gaatgtaaat
     6961 aatcagaata accaaaattt cctgaccatc ctactccata gttccattga ccaccatcaa
     7021 cccatactgc caaaacactt gtagaagcaa gtatactaca taccattaaa gatgcaacac
     7081 caattttctc atgatttatt tctcctatta tcgagagcta ttccgtagaa acagctatag
     7141 taatttgtca acaagtatcg tagtccattg gactcacctt ccttctatct catttcattt
     7201 ttaaacaacg aacttactct taactagaag aatagttctc ttctgtatca ggtctttgaa
     7261 caaccagagt agtattaatc acactctaac tattactcaa gaatcagccc aataaacaat
     7321 atggatagcg ctttcaaatt tttaaactct tatcccatcc ttttatctat ataataagtg
     7381 aaaatataat aactgtcaag taatcgaagt gaattttata aaaaaaatta caagccaaat
     7441 ttgcaaagtt tacaataagc cgctagggca atcgtctatc agaatgtccg tttatttgtc
     7501 aataatccga gaaaatcttg caacgcttag aagtctataa aaactatcaa catttatatg
     7561 acttgcgaat agcaatcctg ctcaaccttt ccacactcta tctatacaat caagataaaa
     7621 acatgtgtaa gcaaatctgc tacactttac tagaggacgc caagaataag aaaagctacg
     7681 ataggctggt tatctgctat gtccgtattg ggatttgtac agacgattct aaacttatcc
     7741 aaaaagggtt ctcccttctg gagctaaccg aggaaacttc tatgctgtct catctcaaaa
     7801 aagaagtaga gatctattac caagcgaagg aaagataaaa aagccgaggg atttcctcga
     7861 ctctttacat attatttgtt cgttagttct taataccagc cattgttaag ccagaagttt
     7921 ttagcagcag tccatgaacc gtaacgtcct gcaacgtagg catctgctac acgttcttgg
     7981 ttttcagctg agtagtcacc gttcaggtat gaatctgtta attggtaacg tccgatataa
     8041 cgtccatttg tagctgtata gctaccacct gattcttttt gagcgatcca ttctttggct
     8101 tctgcttcag atccgcttac agttgaaaca actgtttcac ttactactgg agtttctgct
     8161 actggagctg aaacagtttc atcttgagcg gctggtgccg cataagtagc tggcgctggt
     8221 gttgcaacag gcgctacagg gccatcgata accaactctt gaccaacata aatcaaatga
     8281 atgttatcaa tgtggttgtt ttctgccaat ttttcaactg ttgtgttgtg agtttcagcg
     8341 atttctgaaa gtgtatcacc ttctttaaca gtgtaagttg atgattcttg agcagataca
     8401 aatgatggag caaatactgc aaacaaggca gctactcctg caagagttgc tttaatcttt
     8461 ttagttattg atttcatatt cgaaaattct ccttctttct atagttctat catacccttt
     8521 aaatattacc gtttcttgac acttttatgt agaaatatta caaaattatt ttttatttcc
     8581 ctaaataagg tgttttttgt cataaaagat actattttta tgctatttga ggtattagaa
     8641 aggttttcat ccacaattaa agccaagccc ctcattcttt gatataatag agataagaat
     8701 ttttataagg ggaaactgat gaaatcactt cgttttcaat ctgtctttga tatcatcgga
     8761 ccagttatga ttggcccatc tagtagccat accgctggtg ctgttcgtat tgggaagatt
     8821 gtctcttcca tttttgatga tactccgaca gaagttgaat tccaactttt taactcattt
     8881 gccaagacct atcgtggtca cggaacagac ctagcccttg ttgcaggtat tttaggcatg
     8941 gatacagatg atcctgaaat tccaaacagt ctggagattg cccacaagcg tggtatcaag
     9001 attgtctgga ccattcagaa agacagcaat gcccctcacc ctaacaccac taaaattact
     9061 gttaaaaatg cccacaagac catcagcgtg actggtattt ctatcggtgg aggaaatatt
     9121 caggtaaccg aactcaatgg ttttgccgtc tctctcaata tgaatacacc gactatcatc
     9181 atcgttcatc aagatattcc aggtatgatt gcccttgtta cagaggcgct ttcccgctat
     9241 ggtatcaata tcgcccagat gaatgtcact cgtgaaaaag ctggtgaaaa agccattatg
     9301 attatcgaag ttgacagtcg caactgtgat gaggctatcg aagaaattcg aaaaatccct
     9361 catctccaca atgtcaattt ctttaaatag gaggaagcat gttttattct atcaaagaat
     9421 tggtcgagca agcagatcta gactttcaag gaaatgtcgc agaactcatg attacaacag
     9481 agtttgaatt gaccggtcgc gaacgtgaag aagtcttcct tctcatggaa cgcaatctgg
     9541 aagttatgaa agcctctgtc caacttggcc tcaatgaaaa taaatctcgt agtggcctga
     9601 caggtggaga tgctgccaaa ttggatcact acatcgaaaa cggaaaaact ctgtcagatt
     9661 atacgattct ctcggctgcc cgaaatgcca tcgcagtcaa tgaacacaat gccaaaatgg
     9721 gcttggtctg tgccactcca accgctggaa gtgctggctg tctgccatcc gttctcactg
     9781 ctgctattga aaaattagac ctcagccacg agcaacaatt ggatttcctc tttgctgctg
     9841 gtgcctttgg actagtcatc gcaaacaatg cctccatctc aggtgctgag ggtgggtgtc
     9901 aagctgaagt tggttcagcc tctgctatga gtgctgccgc cttgactctg gctgcaggtg
     9961 gaacacctta tcaggccagt caagctattg cctttgtcat taaaaatatg ctaggcctca
    10021 tctgtgaccc tgttgcaggt ttggtcgaag ttccctgtgt caaacgtaat gccatgggag
    10081 ctagctttgc tttcatcgca gcagacatgg ccttggcagg tatcgaatct aaaatccctg
    10141 tggatgaagt gatcgatgcc atgtaccaag taggagcaag catgccaact gcctttcgtg
    10201 aaacagctga aggtggactc gctaccaccc ctactggtcg tcgcctccaa aaagagattt
    10261 tcggagaata agcttatcaa ataggagaaa ccatgacctc tatcacagcg atttttttcg
    10321 atttggatgg aaccctcgtt gatagttcta tcgggattca caatgccttt acctatacct
    10381 ttaaagagct gggggtgcct agccctgatg ccaaaactat tcgtggtttt atgggaccac
    10441 ctctcgaaag tagttttgcg acctgcctgt ccaaagacca aatttctgaa gccatgcaga
    10501 tatatcgttc ttactataag gcaaaaggca tctatgaagc tcaactcttt cctcagatta
    10561 tagacttgct tgaggagtta tcgagcagtt atccactcta catcaccacg acaaagaata
    10621 catctactgc tcaagacatg gccaaaaact tggaaatcca tcatttcttt gatggtattt
    10681 atggttctag ccctgaagca ccccataagg cagatgtcat tcaccaagcc ttacagacac
    10741 atcaactagc accagaacaa gccatcatca tcggagatac caagtttgat atgctgggag
    10801 ctcgagaaac aggtattcag aaattggccg tcacttgggg atttggagag caagcagatc
    10861 tactaaacta tcaacctgat tatatcgctc acaaaccctt agaagttttg gcgtattttc
    10921 aatagcatag actgggtaac aattccattt cataagaaaa tgaagtaata ctcaatgaaa
    10981 atcaaagagc aaactaggaa actagctgcg ggctgctcaa aacactgttt tgaggttgca
    11041 gatagaactg acgaagtcag ctctaaacac tgttttgagg ttgtggatgg aactgacgaa
    11101 gtcagtaacc atatacggca aggcgacgtt gacgtggttt gaagagattt tcgaagagta
    11161 taagtctcta cataataaaa cgcatattac caaggttgtt aacttgataa tatgcgtttt
    11221 tcttttttat tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaattc
    11281 atctccactg agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac
    11341 attaacctta ccaacgaaaa tcttatccat aacttgattg tcaacgagtt cggttgatac
    11401 caagagttct tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc
    11461 actttcagtg tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg
    11521 tttgcccata tcaaggataa agacttcccc atctttggca taagcaccag catggataac
    11581 cagacggcta gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt
    11641 tacaggccca ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc
    11701 aagaacattc ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt
    11761 gacaatcaac tccgccacgc gcttggttgc tcccataaca tttggtggat tgactgcctt
    11821 atctgtcgaa atcataacca tcttagacac tttagcttca tcaacagcct tagcaacatt
    11881 gtaagttcca cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac
    11941 atgcttgtgg gctgccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa
    12001 caaacgatca tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt
    12061 acgaatcaat tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat
    12121 gcgttcagga ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc
    12181 tcctgtgact aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg
    12241 gatttcctga cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg
    12301 gtgaaggccc tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt
    12361 attacacatc tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat
    12421 gacacgctcg atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac
    12481 aggaatacca ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag
    12541 ttctaattca ctggttggat gttggtaact atccataaag agagccccac catcaccggc
    12601 accaatcaag aaggtccgac ggtgttctcc atcaccacta ccttttttgc gtctggagta
    12661 gattaactgc caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag
    12721 aatgataaaa cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac
    12781 actgctagca gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact
    12841 aatgctcgcg ttcaaccccc aaaaaccaat catcaattga tagaacagga aggccaaact
    12901 cgtatagata atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga
    12961 tacaatgatg gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg
    13021 ttgtttattt aaaatttcca ccagatcaat cacataatct gttagttttt tattcataga
    13081 aatctactcc tccttaaaag agttttacta tatttttatt atagcatatt tttatttatt
    13141 tggcttattt tatccaaata aattattgtt ctcttgtact ccttcttcca tttaaatcct
    13201 ctaattaaac ctacaatcgt cccaaagcca taagcaaagt gaatggaaaa taaaagaaag
    13261 ggcatcacaa ttagaaatcc atttttatgt tttaataaag tcagcaaagt gagtagtgac
    13321 aaaagtagaa aataggcacc taatagtaaa gttatgaata cgaatgtgat cggtaacaat
    13381 gctagactaa acacaagact caaaacaaat aaacaaggaa catagtgaaa taatgataaa
    13441 cacttaaact gaacatgact tgtcaagcca atccacaaac catttaaata cttttgatgc
    13501 agcattttct tgaatgttgg tcgaatatac tgataagata gaatacttgg gctatagcgg
    13561 attttataac catattctcg aattctataa tgaatatcat tatcttcagt tcggccaagt
    13621 tgctcattta ctaaaccaac cttctggaaa acctctcgtt tatacattcc atgaaaaata
    13681 gaagaaacat atctatcctc agaactattt cgataattgg caatgctact gccaaacata
    13741 ttttcctcaa caagatgcaa ggtctctgcc cattttcctt ttccttcgac aatcgtcggt
    13801 ctaggccccc cacagacaaa ttcaccttgt tgaataatag ccacattgtt cattacaaaa
    13861 gtctcagtaa cttttgaatg agcatcaatt tttaaaataa ggtcccctac agaatgttta
    13921 actcccaggt taaaaccact agcttgattt ttcttaggat tgttatacaa tctaattgag
    13981 ttaaactctg tatcttcctt tataaattgc tgaatgatag ctgtggtccc atctgtggac
    14041 atagcattta taaatagaat ttcaatattc tctttaggat aggtttgatt ttttaagtct
    14101 tcaattagac caggcagata tttttcttca ttgtatgcac tgattacaat ggatacgaga
    14161 agactttcaa cattttgagt cactactact ctcctgaatt tttccttcca ccattctatc
    14221 ataattttca agactttccc atttttatct tgaaagccag aaaccttact tgacattata
    14281 gtgaaaaagc cttaaaataa gctgttatta aaatcagcta gaagaggtat tatatgaaaa
    14341 agcaatcact cttttttgtt ccaggtatta tcctgattgg tgtttccttg cgaactcctt
    14401 ttactgtttt acccattatt ttgggaaata tttcgcaagg tctggaggta gaagttagtt
    14461 cgcttggtgt cttgaccagc ctgcctctcc ttatgtttac cctcttttca ccattttcta
    14521 cccaactggc tcagaaaatc ggcttggagc atctcttcac ctacagcctc ttcttcttga
    14581 ccatcggctc acttattcga ctaatcaatc tgcccctgct ctatctagga accttgatgg
    14641 ttggggcaag tgtcgcagtc atcaatgtcc tgcttcctag tcttatccaa gccaatcaac
    14701 caaagaaaat tggttttctg accaccttat atgtaacgtc tatggggatt gcaacggctc
    14761 tggcttccta tctagctgtg cccattacac aagccagttc ttggaaagga cttatccttc
    14821 tcctcacgtt actctgtcta gcaacttttt tggtctggct cccaaatcac cgctataatc
    14881 atagactagc tccacaaacc aaacaaaaaa gtcaaataaa ggtcatgcgt aataaacagg
    14941 tttgggcaat tattatcttt tcaggttttc aatccttgat cttttacacc gtcatgacct
    15001 ggttacctac catgtctatc catgcaggtc tatccagtca cgaagctggc ttgctgactt
    15061 ctatcttatc tctgattagc attccttttt caatgaccat cccaagcctg acaaccagtt
    15121 tatctactcg caaccgtcag ctcatgctca ctctggtttc actagctggt gtggtcggca
    15181 tttccatgct ctttttccca atcaataatt tcatttactg gcttgccatc catctcctca
    15241 tcggaaccgc aaccagtgcc ctcttccctt atctcatggt caacttttca ctcaagacaa
    15301 gcgcccctga aaagacagcc caattgtccg gcctatctca aacaggaggc tatatcctag
    15361 cagcctttgg gccaaccctc tttggttaca gttttgacct gttccactct tgggtaccat
    15421 ctgtagctgc cctcttgctc atcgatatcc tgatgactgt ggccctcttt acagtggaca
    15481 gagcggataa gatcctttaa acttctagtt ttagctagaa gtttttatat ataaaaattt
    15541 tacacatttc tcttgacagg gctttctttt agatgtacaa tgtatgtgta gaaaaattat
    15601 atataaaaat cttacacatt agaaaaggag gtttcccatg tactttccaa catcctctgc
    15661 cttgattgaa tttctcatct tggccgtact ggagcagggt gattcttatg gttatgagat
    15721 tagccaaacc attaagctga tcgctaatat caaagaatcc acactctatc ccattctcaa
    15781 aaaattggaa ggcaatagct ttctgacaac ctattctaga gagttccaag gtcgcatgcg
    15841 caaatactac tccttgacaa acggtggtat agagcagctc ttgaccctaa aagatgaatg
    15901 ggcactctat acagacacca tcaatggcat catagaaggg agtatccgcc atgacaagaa
    15961 ctgaatacct gactcagcta gaactctatc tcaagaaact acctgaagct gaccgtatcg
    16021 aagccatgga ctatttcaga gagctctttg acgatgctgg agtcgaagga gaagaagaac
    16081 tcatcgctag tttgggaact cccaaagaag cggcccacga agttctatcc aatcttctcg
    16141 ataaaaaaat caatgaagca cccgctcaaa aaaataaccg acaaatttta catatcgcct
    16201 tgttagccct ccttgcagca cctatcggca ttcctctggg aatcgccatc ctcgtgaccc
    16261 tgttcgcaat ccttgtagcc gctttgactg tcattctggc tttctttgca gtttccatac
    16321 tgggtatcat cggcggattc ctatttttag ttgaaagttt cactatcctc gcccaagcca
    16381 aatcagcctt tatcttgatt tttggttctg gtttactggc tatcggtgct tcttcgctag
    16441 ttttacttgg catttcctat gtaactcgct tcttcggtct actcattgtt cgtctggtac
    16501 aatttgttct taaaaaagga aagagaggta atcagcatgc gtaaatggac aaaaggattt
    16561 ctcatctttg gtgtggtgac taccgttatc ggctttatcc ttctttttgt aggtatccaa
    16621 tctgacggga ttaagagcct actttccatg tccaaagaac ctatctatga tagccgtacg
    16681 gaaaagctaa cctttggcaa ggaagtcgaa aacctagaaa ttactctcca ccaacacgcg
    16741 ctcaccatca cagactcttt cgatgatcaa atccacattt cttaccatcc atctctttct
    16801 gctcaccatg atcttatcac caatcagaac gatagaactc tgagtctcac tgataagaaa
    16861 ctgtctgaaa ctccgtttct ctcttctgga attggtggga ttcttcatat cgcaagtagc
    16921 tactctagtc gttttgaaga agttattctc cagctaccaa aagggagaac tctaaaaggg
    16981 atcaacatct cagccaatcg cggacaaacc accatcataa atgctagcct tgaaaatgcg
    17041 accctcaata caaacagcta tatcctgcga attgaaggaa gtcgtatcaa aaacagtaaa
    17101 ctcacaacgc ccaatatcgt taatatcttt gatacagttc ttacagatag tcagctagag
    17161 tcaacagaga atcacttcca cgctgaaaat atccaagtcc atggcaaggt tgaactgact
    17221 gccaaagatt atctcagaat catcctagac cagaaagaaa gccaacgaat taactgggac
    17281 atctcaagca actatggttc tatcttccaa ttcacaagag aaaagcctga atcaagaggt
    17341 acggaattaa gcaaccctta caaaactgaa aaaaccgatg tcaaggatca actcattgcg
    17401 agatctgatg ataatattga tctaatatcc acaccaagca gacgttgaca aaaacgctta
    17461 catctgctac tatggaagca tatttatcta accaaaagga ggttctacca tgaaacaaga
    17521 atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc
    17581 tcaagaggtt gcagacaagg ctgaagaaac gatagccaat ctcgatacac caattggaaa
    17641 aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa gccagcaaga
    17701 agagaaaatt gaaactcctg aaggcggtga agcgagaaca gaaatagaag aaaagaaggc
    17761 atctaattct actgaagaag agacagacct ttctaaagaa acagaaaaag tcactatagc
    17821 tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc cacttcttat
    17881 cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta gggataaatg
    17941 gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat ctcctacaag
    18001 taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca ttctgttttc
    18061 tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg gacatatagc
    18121 aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt ctatcatctc
    18181 taccctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag
    18241 acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac aatatagtca
    18301 actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt tctttgatag
    18361 cctacgattt acagccctct tgtgtgtgat tagcattgga atcattctgc ttgccagtct
    18421 ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc aattattctt
    18481 gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag tggcactgat
    18541 tggagattat cttcgtatct tggcctttct ttaaacttca tactcttcga aaatctcttc
    18601 aaaccacgtc agcttcgcct taccgtactc aagtacagcc tacggctagc ttcctagttt
    18661 gctctttgat tttcattgag tagcaatcct gtctttcatg gcaggatttt tctatttcaa
    18721 aaaagcaagt cgattgacct gcttctgctt tactcttctt gtgctaatgc tttaaaatct
    18781 ttgtctaata tgggttgcac ttctatttga ttggcgtcta gttggtggta aaaagatagg
    18841 ggtaatacct ctaagaattt tgcatagtcc aagcgggcaa tggcttcata gtcttctggt
    18901 ttagagccat ctcctgtgat ttgaaccaag tcaatctccc actgcacttc cttatccacc
    18961 aattgctcaa tataggctgc aggaacaaac ggttctctcg gtaaaactgt cttgactcct
    19021 tgagctagat ggtaaacgcc atgcactttt ccttctccat cctgatagaa ggaaactctc
    19081 gcaaagtagg catctgtctc ttgaaccgca cgcacacgcg cttcaaactg agccaaacca
    19141 tcttcctcta aaaagctttt caagtcctca tgactaaaga aaataggatt aaaaattcct
    19201 tggcaaatcg taaaacgaac tgcattatct gtcagatggg cttgaatact tgcttggaaa
    19261 taagcttcaa aatcaaaacc atctagtcct tcaatatcag tccctgtata agcaagcaga
    19321 gcatctaaaa ataacttgat aatccgccag tctgtcttcg tgagtaggtc aggaagatcg
    19381 acacggtaag ccttttgacc atcagcataa ctgaccttaa aaagaaactg tgattgcccc
    19441 actatcgcac attcgatata ctcgagacgg ttaagaggct gacggagata aaccgcatca
    19501 taactatgcg actccaatcc atctaccaag gccaagatcg acttggcagt caaaatctcc
    19561 tgttctccta aaatgctctg tttatttgga ataaaaaatg ttttcgccat aactggactc
    19621 ctttgaaatc gtttacatac agtatacctt atttttctga aagatacaaa aacaaacttt
    19681 atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgccgtaga tatatgtaac
    19741 tgacttcgtc agtcttatct acaacctcaa agcagtgctt tgagcagcct gcagctagtt
    19801 tcctagtttg ctctttgatt ttcattgagt attagatttt tgagtacaaa gcatagaaaa
    19861 acagcccctg aggactgttt gatcttatac agtagctgct tgatccaagc tttcaccgat
    19921 agcggctagg cgctcgataa cttcagcttg tgtcaattca ttttttgaaa catagcggtt
    19981 acgtgggtga acacggcact cgtgtgagca tccacgaagg tacttgtctt cattttcttc
    20041 tgatgtcaag atacgacggt tacagaaggg atttccacag ttgacataac gttcacatgg
    20101 tgttccatca aaccagtctt tccctacgat ggttgggttg acatggttga catcaacggc
    20161 gatacgctcg tcaaatacgt acatttttcc atcccaaagc tcaccttgaa cttctgggtc
    20221 tttaccgtaa gttgcgattc ctccgtgcaa ttggccgaca tctttgtagc cttcacggac
    20281 catccagcct gagaatttct cacagcgaac gccacctgta cagtaaacca cgacacgctt
    20341 gtccatgaat ttttctttgt tgtcacgaac ccattgtggt aactcacgga agttgcgaat
    20401 atctgggcga atagccccac ggaaatgtcc taggtcgtac tcataatcgt tacgtgtgtc
    20461 aaggacaacg gtatctttat caagaagtgc ttctttgaac tcttttggag acaagtaagc
    20521 acctgttgtt tcaagtgggt tgatgtcatt gtcaaagtcg ttgtcttcca aaccaaggtg
    20581 gacaatttct ttcttgtagc gaacaaacat cttcttgaag gcttgttcat tttcttcgtc
    20641 aatcttgaac cagagttctt ccattcctgg aaggctgtga acgtagtcca tgtatttttg
    20701 agttgtttca taatcacctg aaactgttcc gttaattccc tcatcagcga ctaggatacg
    20761 gcctttaagg ccgattgatt tacagaaagc caagtggtct gcagcaaatt gctctgcgtt
    20821 ttcaattgga gtataaaggt agtaaagtaa gacacgaata tcttttgcca taagatttgt
    20881 tctcttttct attcttaaat tttctaaatt ttttatttat ctatactagt atacctgctt
    20941 gaaaaaacga atgcaattta tttgactgga aattgtagag ggttctcgaa atttcctgaa
    21001 tggttaaaat aaggacaaga gaaaacatgg atatctatat ccttgtgcca aaaaaaccac
    21061 tgccctcccc agaccaacct gaggaaagca gtgattctta ttttaggagt taggaatgaa
    21121 tacacgaaat caatttagct gattattttt tgtttttcaa gaattcatcg tattgttttt
    21181 gcatttcgtt caatactttt tcgtaggcac cttcagattt caatttttcc atcaattctg
    21241 gaatcgcttt atctgggtct acagtaccag tgttgatagc tgtatcaaat tgttgcattg
    21301 tgttagcaat agctgagatt tcagatttca cattgtcagt attgaagata aatccaagcg
    21361 ctggagattc tttagcttct gccaattctt tcttagaatt ttcgatttgt tggtctgtaa
    21421 cgttttcgtt gatgtaaagg atccagttgt taccagtgtt ccatccaccc atgtgagtgt
    21481 ttcctttgta gccatcaaga acgcgaacac ggttttcttt accttcaatt ttttcccagt
    21541 tcttgccttc tggaccgtaa acaagaccgt tcaagagttc tgggttcgta ttcaagaggt
    21601 tcaagatttc cattgatttt tctttgttct tagagttgtt tgagatgaca aagttagcaa
    21661 cttgtgttgt ttggtttttc ttgatgaagt tagtaattgg tttgatttgg atatctttgt
    21721 tggcaacacg tgaaagcaag ctgttaccgt agtcagctgg tcctactgtt tcttcacgaa
    21781 cgaaccaagt atcttgttga aggtcaaatg aagtatcgct tgttgcgaca tcttttggaa
    21841 tgtagccagc ttcatagaat ttgtgaagag tcttcaagtg ttctttgaaa cgaggcactt
    21901 cgtaacggtt tacaacttta gtagtatcgc cttcaaggtc aataacgaat ggaagcccgt
    21961 ttgctactgg gtagtcaaaa ttatcagatg ggatgaaaac tttaccaata gcaaatggta
    22021 ctacgtctgg agctttttct ttgatttgtt tcaagactgg ctcaagagtt tcgtaagaag
    22081 taacacctga aatatcgata ccatatttgg caaggagagt tccgttgaag gcaaagtttt
    22141 gagatgatgc aacgttggct gcaactggta cagcataaat cttaccattt acagtattac
    22201 ccttgatata agctgggtca agtgccttgt aaaggtcttt accttctttt ttgtacaatt
    22261 ctgtcaagtc agcataagca cctttttgag catttacaat atagttatct gcaaaggcga
    22321 tatcatagtt ttcaccagat gatgtgataa ctgacatttt cttaccatag tcaccccagc
    22381 caaggtattg gatatccaat ttagcaccaa ctttttcttc gatgattttg ttggcatttg
    22441 ctaacaattc atccaagtta tctggtttgt caccgatttg gtacattttg ataacaggtt
    22501 tgtcacctga atcagcagct tttttgctgt tacctgtcaa gttgccacaa gcagcaagac
    22561 ctgcagccaa agcgactaca ctagcagatg caaaagcata ttttttccag tttttcatga
    22621 taaaaactcc tttttttatt tttaaactta taaacaatgt aatgatctta acttcacgca
    22681 agggaagttt ggaaacaagt gctattcttt cacaccaccg atagtcaaac cttttacaaa
    22741 gtagcgttgg aagaatggat acaaaatcgc gattggaagg gttgctacca caaccatggc
    22801 catacgacct gtttctttcg gtagagcaac tcccagttga ccagtcaagc cgaccgcttt
    22861 ggcaatgtag tccatatttt gttggatttg catgagcaaa tattgcaatg gatacaagtt
    22921 gtcactcttg atgtaaagaa gggcgttgaa ccagtcattc cagaaaccaa gagctgtcaa
    22981 aagcgtgatg gttgcgatac ctggtagtga caatggcaaa cagatttgga agaaaatccg
    23041 ggcctcactg gcaccatcga tacgagccga ttcgagaatg gcttctggaa tggtcttctt
    23101 gaagaaggaa cgcatcaaga tgatattgaa tggtgagaga agcattggaa caatcaaggc
    23161 ccaaacagtg tcaccaagct gaagtacacg ggtcaccatg atataacctg gtaccaaacc
    23221 agcgttgaac aacatactga gaaggacgaa gatggtaaaa aatctgcgat acttaaaggt
    23281 tgtccgtgaa atagcgtagg cataggttgt tgtgataaag acatttgtca atgtcccaac
    23341 tacggttaca aagacagaga tgaagagggc ttgtaggatt ttatccttaa actgtgccaa
    23401 aaactcaaaa ccgtctaagc caaattggga tgggaagaag ctatagccgt attggaggag
    23461 gcttttctcg tctgtcactg aaataatgat aacgaataca aaaggtagga tacaagagag
    23521 ggcaatcaaa cccgaaatga tactgaagaa gatatctgct ttcttactga aggagtgaat
    23581 gccgacatta tcaatttttt cttttttaat tttctttttt gccatattct cctcctttct
    23641 agaacaaagc tgagtttgga tcgactcgtc ttgcaagcaa gtttgatagg ataaccagaa
    23701 tcaaaccaac aacggattgg taaagaccgg ctgctgcagc cataccgata tctgctgtct
    23761 gagtcaaacc attaaaaaca tatacgtcca aaacgttggt tacattgtaa agctgaccag
    23821 cattgtgtgg gatttgatag aagagaccga agtctgcgcg gaagatattt ccgactgcaa
    23881 ggatggtcaa tacagttaca agcggagtca actgaggaat ggttacgttg cgaatacgtt
    23941 gccacttgct agctccgtcc actgtcgctg cttcgtagta ggttggatca attcccatga
    24001 tcgtcgcata gtacatgaca ctgctatatc caaaaccttt ccaaatacct aggaaaagta
    24061 ggagataggg ccagatgccc aggtcagcgt agaaattgac ttctttgaga ccaagacttt
    24121 ccaatagatg attgaacacc cctttatcaa tatttaggaa ggcatctgta aagaaactga
    24181 tgataaccca agacaagaag taagggaaca acatagaagt ttgaaaaatc ttcaccattc
    24241 tcttagaacg gagctcgctg aggataatgg caatccctac agatacaact aaacctagaa
    24301 agataaagcc aagattgtag aggacagtat ttcgtgtgat aataaaggcg tctcttgaac
    24361 taaataagaa tctgaaatta tcgagtccga cccatttact atttatgata ctatctatga
    24421 aaccattact ggtcatgtgg tagtctttga aggcaaccac gttcccaaat actggaatgt
    24481 aaaagaatag aatcaaccag agtgcccctg gcaaaaccat caagagaaag atccagttgt
    24541 ctctcaatgt ttttgaaaac tttttcataa tttcctccct ttttattttg atatccatct
    24601 aaaaattctt ttttagactt ttgataacga ttacattatt agtatactcc tatttgccgg
    24661 ttaggttaaa ctcctaatta tagaaaaaac tccacaaatt atgtagcaga tttaaaactt
    24721 tatcaccact atcaaacaaa tgtcctaaat caattgttta ttttatctct attagcctag
    24781 tgatggcgtc actctgttat aagcatccaa caacggggta tactgaaaaa tctccagact
    24841 agggaactca gcgatagttc ctaatctgga gatttttaat atgttattag gcgtttgctt
    24901 tcaacttagc aataacctct ttaagattat caatcaactc tgcttcagta tgctcagagc
    24961 ctttttcatc tgccaagaac aaaactgctt tttgaagttc ttcttgagag ttttcaagga
    25021 catccttatc tgctgtttct ttgcccgctg tttgtcctca atccttagtt gctgactggc
    25081 tttccttaat ggactctagg gaagcaatgg catctttgac tgtttgcaag atatcacgta
    25141 aaccttgctc tgtcaaacta tcatctgcaa aagctttctt agcctctgcc aaaaccagac
    25201 gtgctgaatc tgtggtagga ttcgatacac ctgtcaatga tctcaaaaga ttttctaaag
    25261 tttgagtctg cttactaata ctagactaaa atcaaaaagc attatataac agtgatatga
    25321 aatcaactaa agaagaaatc caaactatca aaacactttt aaaagactct cgtacagcta
    25381 aatatcataa acgccttcaa atcgttctat agtaaaatga aacaagaaca ggacaaatcg
    25441 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
    25501 ttcaatccat tatatttcgt ctgatgggca aatcttataa agagattata gagcttttat
    25561 agtgatttga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaat
    25621 attttagcag ccaaggtgta ctgttataaa ttcaatacac tatacttggt ggtttagctc
    25681 tcctgttttc tcttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
    25741 gtgtgatgct tctgttatac tacctgttcg ctcacaataa gagagaactt ttttacgaaa
    25801 atctattgaa tatgccataa aaggattata ccacattgtg tactattttt ggttcatttt
    25861 actatatcac tttggactat atcggtctag ttatgtctca acgattatag ctggatacta
    25921 agagaaatca aaaaagcact aagggagaac gtcccaaagt gcttaatatc aaggcctcaa
    25981 agcctatctt attcaataaa atattacaac attttgttgt agaattcaac gacaagtgct
    26041 tcgttgattt ctgggttgat ttcgtcgcgt tctggcaagc gagtcaatga accttccaat
    26101 ttttcagcgt cgaatgatac gaatgctgga cgtccaagag tagcttctac tgcttcaagg
    26161 attgctggaa ctttcaatga tttttcacga actgagatca cttgacctgg agttacgcgg
    26221 tatgatggga tatcaacgcg tttcccgtca acaaggatgt gaccgtggtt tacgaattga
    26281 cgagcttgac gacgagtagt cgcgagacca agacggtaaa caacgttatc caaacgacgt
    26341 tccaaaagaa gcataaagtt gaaacctagg attccgcctt tgatttttgt agcttgtacg
    26401 aacaagttac ggaattgttt ttcacctaca ccgtaagtga aacgaagttt ttgtttttca
    26461 gccaattgca aaccgtattc tgacaattta gaacggttgt ttggtccgtg ttgtcctggt
    26521 acgtagttac gacgtgccaa ttctttacct gtacctgtaa gtgaaaggcc aaggcgacga
    26581 gcttgtttcc aagatggtcc tgtataacgt gacatatgaa tgtcctcctg atataaataa
    26641 tatttcggtg gaaatagtca cttagaaagc cctgattcgt gcagatgccc ttcgcctaaa
    26701 cagccaaggt tacttgtcat aagacacctg ttgacgagct tcatgctttc ctgctgatat
    26761 ttcacacaaa atccatttta ccatgaatag ctggatttgt aaaggggttt taggctttat
    26821 tttcactacc agagaggttg agaacgaggg taaaggtact tcctagaccg tactggctgc
    26881 tgactgtgat ttccccaccc aattgatggg ccaattcacg cgcaatcgca agtcctaatc
    26941 catgaccacc tgtcttcatg ttacgcgaag tttcgacacg ataaaggcgt ttgaaaatat
    27001 tttccaaatc ctctggggca atgccctgcc cttcatcggt cacactgatt gaaagctggc
    27061 ccttctccag cttagtcacc acttccagct tggttcctgg agcagaatat ttaaaagcgt
    27121 tatcgaccag attcaccaaa atacgagaaa gcttagcata atctccctca atccgggcag
    27181 actctgggat tacctgcaag tggacatctc ttctctcctg ctcaatcaaa aactgaaatt
    27241 cactcatgca ctcaattaag agcttgtcca gaaaaatact gtctttactg gtagtttcca
    27301 cctgatttct agctgtattt agggtcaaaa aattcaactc ctcaaccagt ttattgagcc
    27361 tctccgtctg gcgtccaatg gttgctagat aatgagcttg ctccgactcc ttgataatcc
    27421 catccaaaat cccttctacc gtcgcttgga tcgaagtgat aggagtctta atatcatgcg
    27481 acaactgggc aatcatcaag cccttttctc gttcgctttc ttccaaggaa tcaaagctta
    27541 cctgcaaatc atgggacatc tcattaaaag tttgccctaa ttgctgaaat tctacaggac
    27601 cttgaacctc caaatttgaa ggaaaatcct tggccgctac ccgcttggca tgctccttga
    27661 gtttgcccaa cgacgtaaag actggcaata ggagaaagag actaatccca gcaccgacaa
    27721 ggctggcaac gatggtcatc ccaagcaaaa agtaaatctc gcctttcgca atcagcattt
    27781 tttgaacagc ccaaaaaaca accaaaatgg ttaagagggt tgaaataata tatccaacca
    27841 aaatataact ttttagtttc atgtttgtcc tctcggtttc tctatcttat atcccaaccc
    27901 ccaaactgtc ttaatagtgg gcgtttggtc actactatat tttgccagct cctgtcgaag
    27961 agcatggata tgcacattca aggtattggt gtcatccacg tagtcttctt tccagatctt
    28021 ttcatagagg tctgtcttgg agaaaactcg ctctggattg ctagctaaaa tccacagcaa
    28081 ttcaaatgat ttaacagtta aatccagcat ttcttctcct atttgaactt catgactact
    28141 atgattcatt tttagattgc caagggaaat cagctctgtt tcgcccccac gatgaaggcg
    28201 gcgcaaaata ttgtggacac gcaaaaccag ctcacgtggg ctaaaaggct tagcaataaa
    28261 atcatctgct cccaagctca ggccgtaaat cttgtcctgt tcactggtct tagcagtaat
    28321 aaataggaaa ggctgctctg gtgataagta ttgaacctca ctgattaaat cataaccatc
    28381 catccgaggc atcatgacat ctgtgataat caaatcaatc ggttttttct tgaacagctc
    28441 tagcgcttcc agtccatcat gggctaccaa gacctgataa cctgcctgaa ttaagtatct
    28501 ctgatgaata tctgtgattt ctacctcgtc gtcaacgagt aaaattgtct ttcccatctg
    28561 tctctccttt gataaaaaca gtgctatact gctttaagta taacactatt tttattgttt
    28621 tacgatgatt ttaatctgct attgaaagaa agtcctgatt gctgattgag ttgttaaact
    28681 aatcttagtc agcccactat ccatcattta tttccttagc tgattagttt tcttcttttt
    28741 tgtttttcaa acctagacca ccgagtaaac ctgcaagcgc aagcccaagg aaaccaatac
    28801 ttgccattga tgtttgagtc tcaccagtat ttggtagcat agctttatcc tctgacatca
    28861 tcgtatcaga catcttgtta gcagaagcag ccatgttttc acctgccatc gtgttggtag
    28921 aacttgtcat ggtgtcagca ggcatgctat ctgtagtacc tgtagcatga ttgtgattca
    28981 tcggagtcac gccagaacca gagttagaag gtgataatga accatttgct gtgtctgatg
    29041 tttctttaac atttat
//
LOCUS       DAVDFK010000024        25847 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.24, whole genome shotgun sequence.
ACCESSION   DAVDFK010000024 DAVDFK010000000
VERSION     DAVDFK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.24"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            136..1506
                     /locus_tag="VUR04_001322"
     CDS             136..1506
                     /locus_tag="VUR04_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET5341213.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILLQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            1882..2838
                     /gene="lytA"
                     /locus_tag="VUR04_001323"
     CDS             1882..2838
                     /gene="lytA"
                     /locus_tag="VUR04_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET5341214.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            3184..3345
                     /locus_tag="VUR04_001324"
     CDS             3184..3345
                     /locus_tag="VUR04_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341215.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            3332..3538
                     /locus_tag="VUR04_001325"
     CDS             3332..3538
                     /locus_tag="VUR04_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341216.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            3584..4078
                     /locus_tag="VUR04_001326"
     CDS             3584..4078
                     /locus_tag="VUR04_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341217.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            4071..4496
                     /locus_tag="VUR04_001327"
     CDS             4071..4496
                     /locus_tag="VUR04_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341218.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            4904..5899
                     /locus_tag="VUR04_001328"
     CDS             4904..5899
                     /locus_tag="VUR04_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341219.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            5889..6440
                     /locus_tag="VUR04_001329"
     CDS             5889..6440
                     /locus_tag="VUR04_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341220.1"
                     /translation="MPANTKVIFQEMFVDFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKEGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            6499..6759
                     /locus_tag="VUR04_001330"
     CDS             6499..6759
                     /locus_tag="VUR04_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341221.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMYRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
     gene            complement(7500..8300)
                     /locus_tag="VUR04_001331"
                     /pseudo
     CDS             complement(7500..8300)
                     /locus_tag="VUR04_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            8425..8883
                     /locus_tag="VUR04_001332"
     CDS             8425..8883
                     /locus_tag="VUR04_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET5341222.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            8896..9504
                     /locus_tag="VUR04_001333"
     CDS             8896..9504
                     /locus_tag="VUR04_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341223.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            9575..9907
                     /locus_tag="VUR04_001334"
     CDS             9575..9907
                     /locus_tag="VUR04_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341224.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            9918..11327
                     /gene="ply"
                     /locus_tag="VUR04_001335"
     CDS             9918..11327
                     /gene="ply"
                     /locus_tag="VUR04_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET5341225.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKIMAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            12208..12924
                     /locus_tag="VUR04_001336"
     CDS             12208..12924
                     /locus_tag="VUR04_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5341226.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            13048..13497
                     /locus_tag="VUR04_001337"
     CDS             13048..13497
                     /locus_tag="VUR04_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET5341227.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            13536..14357
                     /locus_tag="VUR04_001338"
     CDS             13536..14357
                     /locus_tag="VUR04_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341228.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQAVTRGSIMAIWAIGKILGHSEYWLWPVLVAVIINVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            14364..15395
                     /locus_tag="VUR04_001339"
     CDS             14364..15395
                     /locus_tag="VUR04_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5341229.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQKPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVRFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            15460..15822
                     /locus_tag="VUR04_001340"
     CDS             15460..15822
                     /locus_tag="VUR04_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET5341230.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGEKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVRIEEIDDPLMQEIHRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            15819..16322
                     /locus_tag="VUR04_001341"
     CDS             15819..16322
                     /locus_tag="VUR04_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET5341231.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            16436..16882
                     /locus_tag="VUR04_001342"
     CDS             16436..16882
                     /locus_tag="VUR04_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341232.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            16887..17561
                     /locus_tag="VUR04_001343"
     CDS             16887..17561
                     /locus_tag="VUR04_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341233.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWCVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            17767..17916
                     /locus_tag="VUR04_001344"
                     /pseudo
     CDS             17767..17916
                     /locus_tag="VUR04_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860718.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
     gene            18253..18552
                     /locus_tag="VUR04_001345"
     CDS             18253..18552
                     /locus_tag="VUR04_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET5341234.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            18549..18866
                     /locus_tag="VUR04_001346"
     CDS             18549..18866
                     /locus_tag="VUR04_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET5341235.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            18882..19508
                     /locus_tag="VUR04_001347"
     CDS             18882..19508
                     /locus_tag="VUR04_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET5341236.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            19541..20302
                     /locus_tag="VUR04_001348"
     CDS             19541..20302
                     /locus_tag="VUR04_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET5341237.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            20380..20775
                     /locus_tag="VUR04_001349"
     CDS             20380..20775
                     /locus_tag="VUR04_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET5341238.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            21045..21329
                     /gene="groES"
                     /locus_tag="VUR04_001350"
     CDS             21045..21329
                     /gene="groES"
                     /locus_tag="VUR04_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET5341239.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            21345..22967
                     /gene="groL"
                     /locus_tag="VUR04_001351"
     CDS             21345..22967
                     /gene="groL"
                     /locus_tag="VUR04_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET5341240.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            23105..23860
                     /locus_tag="VUR04_001352"
                     /pseudo
     CDS             23105..23860
                     /locus_tag="VUR04_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            24325..25098
                     /locus_tag="VUR04_001353"
     CDS             24325..25098
                     /locus_tag="VUR04_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5341241.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EIKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRDNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTEGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            25111..25407
                     /locus_tag="VUR04_001354"
     CDS             25111..25407
                     /locus_tag="VUR04_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341242.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNE"
     gene            25483..25847
                     /locus_tag="VUR04_001355"
                     /pseudo
     CDS             25483..25847
                     /locus_tag="VUR04_001355"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT         7964 a         4410 c         5630 g         7843 t
ORIGIN      
        1 tagatcgaaa ctagaatagt acacatctac ttctaaaaca ttgttaaaaa tcgatttgac
       61 tttccttatt tcattccgct atatataagt ttgctgtttc ttgtcgctcc tctggaaagc
      121 tgatataata gctttatgaa taaaaaacga acagtggacc tgatacatgg tccgattctt
      181 ccctcgctct taagcttcac ctttccaatc ttgctatcaa atatttttca acagctctat
      241 aacactgctg atgtcttgat tgttggacga tttcttggtc aagaatcctt ggctgcagta
      301 ggagcgacga cagcgatttt tgacctgatt gtaggtttta cacttggtgt tggcaatggc
      361 atggggattg tcattgctcg ttattatggg gctcggaatt tcactaaaat caaggaagca
      421 gtagcagcca cctggatttt aggtgctctt ttgagcattc tagttatgtt actgggcttt
      481 cttggcttgt atcctctctt gcaatactta gatactcctg cagaaattct tcttcaatct
      541 tatcaatata tttctatgat tgtgacctgt gtaggtgtca gctttgctta taatcttttt
      601 gcaggcttgt tgcggtctat tggtgacagt ctagcagccc tgggatttct gattttctct
      661 gccttggtta atgtggttct ggatctctat tttattacgc aattgcatct gggagttcaa
      721 tccgcaggac ttgctaccat tatttcacaa ggtttatcag cggttctctg cttttattat
      781 attcgtaaaa gtgtgccaga actcttgcca cagtttaaac atttcaaatg ggacaaaagc
      841 ttgtacgcgg atctcttgga gcaaggtttg gctatgggct tgatgagttc aattgtatct
      901 atcggcagtg tgattttaca gtcttctgtt aatacatttg gtgcagtgat tattagtgcc
      961 cagacggcag ctcgacgcat tatgaccttt gcccttcttc ctatgaccgc tatttctgca
     1021 tcaatgacga cctttgcttc tcagaatcta ggagctaagc gacctgaccg cattgctcaa
     1081 ggtcttcgaa tcggcagtcg tttaagtata tcctgggcag tttttgtttg tattttcctc
     1141 ttttttgcca gtccagcctt ggtttccttc ttggctagtt cgacagatgg ttacttgata
     1201 gaaaatggaa gtctctatct gcaaatcagt tcagcctttt atcccatttt gagcctcttg
     1261 ttgatttatc gcaattgctt gcagggcttg gggcagaaga tccttcctct agtttctagc
     1321 tttattgaac taatcggaaa aatcgttttt gtggttttga ttattccttg ggcaggatat
     1381 aagggtgtta tcctttgtga acctcttatc tgggttgcca tgacagttca actgtacttc
     1441 tcactattcc gtcatccctt gataaaagaa ggaaaggcaa ttttggcaac caaagtgcaa
     1501 tcctagttgg atttactgaa taaaatccat ttcctctagt gaacatcgaa aaaacttgtg
     1561 ttctcttctt tagtttggtg ttgaaaatag tttaacagac ttttgacttc ttttatatga
     1621 tataataaag tatagtattt atgaaaagga catatagaga ctgtaaaaat atacttttga
     1681 aaagcttttt agtctggggt gttattgtag atagaatgca gaccttgtca gtcctattta
     1741 cagtgtcaaa atagtgcgtt ttgaggttct atctacaagc ctaatcgtga ctaagattgt
     1801 cttctttgta aggtagaaat aaaggagttt ctggttctgg attgtaaaaa atgagttgtt
     1861 ttaattgata aggagtagaa tatggaaatt aatgtgagta aattaagaac agatttgcct
     1921 caagtcggcg tgcaaccata taggcaagta cacgcacact caactgggaa tccgcattca
     1981 accgtacaga atgaagcgga ttatcactgg cggaaagacc cagaattagg ttttttctcg
     2041 cacattgttg ggaacggttg catcatgcag gtaggacctg ttgataatgg tgcctgggac
     2101 gttgggggcg gttggaatgc tgagacctat gcagcggttg aactgattga aagccattca
     2161 actaaagaag agttcatgac ggactaccgc ctttatatcg aactcttacg caatctagca
     2221 gatgaagcag gtttgccgaa aacgcttgat acagggagtt tagctggaat taaaacgcac
     2281 gagtattgca cgaataacca accaaacaac cactcagacc atgtggatcc atacccttac
     2341 ttggcaaaat ggggcattag ccgtgagcag tttaagcatg atattgagaa cggcttgacg
     2401 attgaaacag gctggcagaa gaatgacact ggctactggt acgtacattc agacggctct
     2461 tatccaaaag acaagtttga gaaaatcaat ggcacttggt actactttga cagttcaggc
     2521 tatatgcttg cagaccgctg gaggaagcac acagacggca actggtactg gttcgacaac
     2581 tcaggcgaaa tggctacagg ctggaagaaa atcgctgaga agtggtacta ttttgatgta
     2641 gaaggtgcca tgaagacagg ctgggtcaag tacaaggaca cttggtacta cttagacgct
     2701 aaagaaggcg ccatggtatc aaatgccttt atccagtcag cggacggaac aggctggtac
     2761 tacctcaaac cagacggaac actggcagat aaaccagagt tcacagtaga gccagatggc
     2821 ttgattacag taaaataata atggaatgtc tttcaaatca gaacagcgca tattattagg
     2881 tcttgaaaaa gcttaatagt atgcgttttc ttgtggagat atttccttca atgtttgcta
     2941 ctatattaaa caaaaatcag aaagcgaact agaaagttat gctcaaataa aatctaaatt
     3001 tgacaatgta aaccgagtcg gatagcttta agtactgttt tgaggttgaa gatacgattt
     3061 ttgataggaa ctcatcaatt ttagattttt aagcagcatc aataaattgc ttccttgttt
     3121 tgtcataatt tttttattta aaaaattatg acaagagtgt gctattcttt ttatgagagg
     3181 tgtatgaata tgataaatgt atgtgatgtt ggaaaaagaa taaaagaact tagaatatct
     3241 tcaaatctta ctcaagataa gattgctgag tatttgtctt tgaatcaaag catgattgcc
     3301 aaaatggaaa aaggtgaaag gaatatcacg aatggattta agtaataaag cttcaaatct
     3361 tagaaaaaag ttgggagctg atggtgaatc gccgatagat atttttaaat tggtacaaaa
     3421 gatagaaaat ttgacgctgg tattttatgg actcggaaag aatattagcg gagtctgtta
     3481 taaaggaact cagttcagtc tcattgcagt caattcagac atgccattag gaaggtaaag
     3541 attttcttta gcacatggac tgtatcatct ttattatgat gaggtgaaga agagttcagt
     3601 cagtcttatc ttgattggtg aaggagatga aactgaaaga aaagcggatc agtttgcttc
     3661 ttatttttta attttcccat cttcactgta taggatggtt gaggaaatca gagaaaatgc
     3721 caatagaact catcttgaag tagaagatat tataaaattg ggtcagtttt atggtatcag
     3781 tcataaagct atgttatata gattgagaaa tgatggatac cttgatgcag aagaaattaa
     3841 aaatatggat attagtgtta tagagacagc ttcaagatta ggctatgata caagtttata
     3901 tcgtcctttg tcagaaagta aaaaggaaat ggtattagga cactatatta aatcgactga
     3961 acaactttta gaaaataaca gaatttcgca agggaagtat gaggaactgt tactagatgc
     4021 tttcagatat gatattgtat atgggctaga tgaagagggg gagttgtcgt ttgactagtc
     4081 gtgtatttat tgatgcagat tgtatttcag catttttatg ggttggcact gaacatcttt
     4141 tagaaaagct ctattcgggt aaaattgtta ttccacaaga ggtgtatgat gaaatcaata
     4201 tacctacaat tccccattta aaatctagga tagaccagtt ggtaactaag ggttcagctg
     4261 agattgtgag catagacatt ggaactgaag aatacgcatt atatagagat ttaacaagaa
     4321 atcatgatag taacaagatt attggtaagg gagaagcgac ttctattttc ttagcgaaaa
     4381 agcataatgg gatattagga agtaataacc taagagatgt taaaccatat gtagaagaat
     4441 tttctttaga acatatgaca acaggagata tactgattga agcgtttaaa gcgtaattta
     4501 ttactgaaca agagggcaat catatctgga ataatatgct taaaaagaga aggaaaattg
     4561 gtgcaaattc attttcagac tatcttcgtg gaagtattca tcaaaataga caaaaataaa
     4621 tttggataaa tcgaactcac tattcaggag gcatatgagc aattcgaaaa agaaaagtgt
     4681 caaattgagc ctataggagt agaagtgaaa tagtaagtcc tgcatagtgg atgagagaaa
     4741 agttctcctt gaagttttcc tgaactatca gtcgcatgtc aaacgatatg tagggtaatg
     4801 tgagagggga tagcgagtag tttttggtta ttttatcaaa aaacttatat tttattatac
     4861 cgaatgataa aatataataa aaatgataga ataaggaaaa aacatgaatg tcaaaaagat
     4921 aatgtcaatt tttcaatcct tttatgttga tgtcagtatt gaggaactga ctttgacttt
     4981 accaatcagt tttgtaaaaa ggtttgagta tactcaaatg acttttcata aggaatcatt
     5041 tttattgatt aaagaaaaga gaagggggag tttgagttca tttgttactc aggctcgcac
     5101 tatgggtgaa aaagccaata tggatgttgt tttggtgttt tcgaagttat cagacagtga
     5161 aaaaaagcaa ttacttcaag ctagagttcc gtttgtagac tttaagggaa acctcttctt
     5221 ccctccattg ggactagtac tgaatgcgaa tgatactgaa gtccctaagg aattaacacc
     5281 tagcgaacaa ttaacgtgga ttgccttttt attgacaaaa ggtcaaaaag tagtagatgt
     5341 tgatttgctt tcacaagtca ctggacttcc aaactcaaca atttataggt gtttgaggac
     5401 ttttaaagct ttatattggt taaacaagca aaataagctt tacacatata cggtgtcaaa
     5461 gaaagaatta ttcttaaaat ccgtgtcatg tttatttaat cccatcaaaa aacggatttt
     5521 attgccagat ggcgatataa agcagataaa atctgtttct aaccttctat atggtggtgc
     5581 ttatgctttg tcgcattcaa cttttttagc tgaaacggat gaaaatatta gctatgtcat
     5641 atggcagaga aaattcaatc agttatcctt gccactttct cagcatgttt taaaaggaaa
     5701 gatgctagag atatggaaat atcgtccttt tgtatctgag ttttggaatg attttaaaaa
     5761 taatcatgat aaacaatttg tagatccgat ttctctttat ttgaccttaa aagatgatga
     5821 tgacccacgt atagaggaag agagtgaagc actagaaaat atgatattac agtatctggg
     5881 agaagatgat gccagctaat acgaaagtta tttttcaaga aatgtttgtg gattttcaga
     5941 actattatgt tctgattggg ggaactgcta cctctatcgt attggattcg caaggattta
     6001 aaagtcgcac aacaaaagat tatgatatgg tcatcattga tgaagtaaaa aataaggaat
     6061 tttatactac cttgaatcac tttttagaat tgggagagta tcaaggaagt cagaaagatg
     6121 agaaagcgca gctttttcga tttacaacaa ctaatcctga gtttccttct atgattgaac
     6181 tatttagtat cttaccagaa tatccattaa agaaggaagg tcgagaaatt cccttatatt
     6241 ttgaccaaga tgctagttta tcagccttat tattggatga agattattat aatatattgg
     6301 tgcatgtaaa agaaactatt caggggtatt cggtattgag taattgtggt ctatactctt
     6361 cgaaaatctc ttcaaaccac gtcagcttcc atctacaacc tcaaaacagt gttttgagca
     6421 gcctgcagct agcttcctag tttgctcttt gattttcatt gagtattaat tatttttaag
     6481 gctaaagctt ggctggatat gagagagcgc tctgccacag gtgctcaagg tttaagtaag
     6541 tccattaaaa agcatttgaa tgaccttacc cgtttgacag cttccttgct aggagatgaa
     6601 aagttatcgg ctataacatc aagtagtgcg gtaaaagcag acatgtaccg ctttgtgata
     6661 gaattagagc ctgtgaagtc aactattctt caaaataatg acatttcatt ggatcaaaat
     6721 gaaatttttg aaattctgaa aaattttctc gatggttaaa ataattgtag cgagatggct
     6781 atattgaatt cgtctatatc tggaaactag aaaaaacttc aatttcagga gaaaatgaag
     6841 tcaatcttcc cacaatcaaa cgtatagtat caaggttttt caagacctga tattatgcgt
     6901 tttttgcttt tcaaaacttt ttgcccagtc tttgttttta tcctctagtc acttgatttg
     6961 tttcaggtgg ttttttagta tagtagaatg aaacgagaac aggacaaatt gatcaggaca
     7021 gtcaaatcga tttctaacaa tgttttagaa gcagaagtgt actattctag tttcaatcta
     7081 ctatagttaa atctgcggtc aagtctactg gtgaatctat gattgtaata ctcttccaaa
     7141 atctcatcaa ccacgtcagt cttgccttgc agtctgtatc ttactgacca agctagtgat
     7201 ggatttagaa taggtgattt ggagcgtcct attggctagg aaatgctgct catagtcctt
     7261 tgctgaggct agggtgtttc aacattcaac actcaactgg ttgatctagt tgataggaag
     7321 ggaattacta taaaatactc aggcttccat catatttttt gaaacgattg tgtaatcaaa
     7381 atgtaccaat attgtagtat tagtacagaa gatgttgtga atggataaat atatcataac
     7441 tgctgtctca aaaagatttc atatgtctgt gcatatataa tagacttcct gcgaaaccaa
     7501 aatcctagtt catgattgat aataccagca atcaaattca ttcgcaatcc gaagcgttta
     7561 cgatgatttc gataggttgt tgaaatcatt ttaaacgttt ttactttggc aaagatgttc
     7621 tcaaccttgc ttctctcctt ggatagcgca tggttacagg ctttatcttc aactgttagt
     7681 ggcttgagtt tgctggattt acgtggagtt tgtgcttgag gatatatctt catgagccct
     7741 tgataattac tgtcagccaa gattttacca gcttgtccga tatttccgcg actcattttg
     7801 aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaataat tcttccttga
     7861 cttgtgacaa tcgcttgagc cttcatagcg tggcatttct ttttaccaga atcattcgct
     7921 aattgttttt tagggcgatt gatttttact tccgtcgcat caatcattac cgtgtcctca
     7981 aaactaagag gagttcttga aatcgtaaca ccactttgaa caagagttac ttcaacccat
     8041 tggctccgac ggattaagtt gctttcgtga ataccaagat cagccgcaat ttcttcataa
     8101 gttcaatatt ctcgcacata ttgaagagtg gccataagaa ggtcttctag gcttaattta
     8161 ggttttcgtc caccttttgc gtgtttaagt tgataagctg tttttaatac agctaacatc
     8221 tcttcaaaag tggtacgctg aacaccaaca agacgcttaa atcgtgtatc agttaattgt
     8281 ttacttgctt cataattcat agaactacta taccatattt tgtttcgcag ggagtctaat
     8341 aagttatagt ccagttttta ctatactttg atattcaaat atgttatact atggttatca
     8401 aagtaaatga aaggagttac gaatatgacg ccagaagaaa tgtacctgac agagcgatta
     8461 gacgtacaga tagctcattt tttaaagaaa agcgttcaac atcgtaggcg ctataaggta
     8521 ttaaaaataa cagaaatcgt ggcaggtttc ctcatagctg tcttttgtgc tattcctatg
     8581 ccaggtgatc gctaccgttt gatttcggtt gccttatcca gtctcggctt gctgtgtgag
     8641 gggattatca atttgtataa tgcaaaggaa aattggattt cttaccaaaa aactgcgcaa
     8701 ctcctggaga aagaaaaatt cctctatcaa tgccaaacgg agaaatatgc aggaaagacc
     8761 aaggcttttg ccctatttgt caagacatgc gaaggtctta tctcagagga gattaaccag
     8821 tgggaaagta tccagtcaaa agaagtggca gctagtgcag atgctccagt taaaaaagag
     8881 taggaggtag aggaaatgtc tcaatccagc tacctgtcgc ccttgctctg gttaaaaaaa
     8941 gaagccgata aggaaaagat gagcgcgacc cagtgccaga tatttttctt ttactatcaa
     9001 atgtttgagc tcttatttgc tagagaaagc gacatgaaag acttatgtct gggaacgaaa
     9061 ggtttttatt tctcgcagtt agagaaaaat ttgctttctg gagtttcccg atttctaaaa
     9121 aacttggagg ggaaagtaac tctcaaggct aaccaagaag tatcagctcg caaagccctt
     9181 tttctagcct tgacaactag ccaatcagat tggcaggagt tagctcctgt ttttgatttt
     9241 tatcagacta tcgggaggct tgaaaatcct tctctcttga gttctcagga cagacaacat
     9301 ctgatgtgga tttaccagtc agctttggag aaggattata ttgtcaaggt tattggcgac
     9361 aagcattttg tattgaagag acaagatgct actaaattga cagcgcgcca aactcaaact
     9421 ttggaaattc tgagtcaatc agaagacttg gtcaatcctg tctatgttac attaggagaa
     9481 aagggggtgc tcttgcttga ttaagagagg agatgttgta gctctttatt tgccttttcc
     9541 gactattagt agcgatttgg ctgtgaagaa tcatatgtat atctgtattg acaacagcat
     9601 gactaaaaac aaagagttgg ttaaaaatca gaccttcaaa ccagctctct tgaccagacg
     9661 tttggtcaag aactttatga tagaagagcc ggatctagct cgtaatcctt ttacaagacc
     9721 aaccttgatt gacttagata aggtatttat gttggataat acggttattc cgacttctta
     9781 tctagccaga cggcgacgca atgtctcaga agaattgtac gaggaaattt tagatcactt
     9841 agtccaacca cggctgattt cgctgaacaa gtctgagttt atgcaactca atccaggaac
     9901 ttattaggag gtagaagatg gcaaataaag cagtaaatga ctttatacta gctatgaatt
     9961 acgataaaaa gaaactcttg acccatcagg gagaaagtat tgaaaatcgt ttcatcaaag
    10021 agggtaatca gctacccgat gagtttgttg ttatcgaaag aaagaagcgg agcttgtcga
    10081 caaatacaag tgatatttct gtaacagcta ccaacgacag tcgcctctat cctggagcac
    10141 ttctcgtagt ggatgagacc ttgttagaga ataatcccac tcttcttgcg gtcgatcgtg
    10201 ctccgatgac ttatagtatt gatttgcctg gtttggcaag tagcgatagc tttctccaag
    10261 tggaagaccc cagcaattca agtgttcgcg gagcggtaaa cgatttgttg gctaagtggc
    10321 atcaagatta tggtcaggtc aataatgtcc cagctagaat gcagtatgaa aaaatcatgg
    10381 ctcacagcat ggaacaactc aaggtcaagt ttggttctga ctttgaaaag acagggaatt
    10441 ctcttgatat tgattttaac tctgtccatt caggcgaaaa gcagattcag attgttaatt
    10501 ttaagcagat ttattataca gtcagcgtag acgctgttaa aaatccagga gatgtgtttc
    10561 aagatactgt aacggtagag gatttaaaac agagaggaat ttctgcagag cgtcctttgg
    10621 tctatatttc gagtgttgct tatgggcgcc aagtctatct caagttggaa accacgagta
    10681 agagtgatga agtagaggct gcttttgaat ctttgataaa aggagtagct cctcagacag
    10741 agtggaagca gattttggac aatacagaag tgaaggcggt tattttaggg ggcgacccaa
    10801 gttcgggtgc ccgagttgta acaggcaagg tggatatggt agaggacttg attcaagaag
    10861 gcagtcgctt tacagcagat catccaggct tgccgatttc ctatacaact tcttttttac
    10921 gtgacaatgt agttgcgacc tttcaaaata gtacagacta tgttgagact aaggttacag
    10981 cttacagaaa cggagattta ctgctggatc atagtggtgc ctatgttgcc caatattata
    11041 ttacttggaa tgaattatcc tatgatcatc aaggcaagga agtcttgact cctaaggctt
    11101 gggacagaaa tgggcaggat ttgacggctc actttaccac tagtattcct ttaaaaggga
    11161 atgttcgcaa tctctctgtc aaaattagag agtgtaccgg gcttgcctgg gaatggtggc
    11221 gtacggttta tgaaaaaacc gatttgccac tagtgcgtaa gcggacgatt tctatttggg
    11281 gaacaactct ctatcctcag gtagaggata aggtagaaaa tgattaggag agaagaatgt
    11341 ttgcgacaaa aagaggcgat gagctctctg cggatatctg aaagtttatc tcttgcctag
    11401 cgatttccat tggagtatgc tcgtgatgtt aaaatgaatc tatcaaacag aatgtgtaaa
    11461 aaagtaaaaa gggtagccaa ttccttgata tacaggggat tgattatcct ttacttgttt
    11521 tagatgattg gaaattcaag aatgacacgt atcggaaata ttttgctgtt tatatctaat
    11581 acccatttat ggaaaaaatg aaattaaata tgaacaaatc aattgctagc aatggtttag
    11641 aagtgccagt gtactagtct aatttctcca tcttgggaac acgtaaatta tactcttcga
    11701 aaatctcttc aaaccaggtc agccctatcc gcaacctcaa aacagtgttt tgagcaacct
    11761 gcggctagct ttctagtttg ctttttgatt tttattgagt attagaggtt tgcttagaaa
    11821 ctcttctatt gatttcttag aatacaatag cgcctataag agctgttgaa tttcaaagta
    11881 tttacttgaa ctatgatatg tctggagtag actgtcaaca aaaggtgcag tatgattgtt
    11941 tttgtcgctt atatctacaa acttcaaaca gtaatttgag ctgactttgt caaacttggc
    12001 tgaaactttc tatttgcaga taatggtcta gtttgttttt tgaatgtgga tgagtgtctg
    12061 ttgataaaga tagaaaggca agaccatctt agcaggtaaa gtgctatcct agcttgattt
    12121 gctaataaaa tccatttcct ctagtgaaaa tcaaaaaaac ttgtgttata ataagaaaga
    12181 ttaaaatgtg aaaaaaggag attcctaatg ggacgtaaat gggccaatat cgtagccaag
    12241 aaaacggcta aagatggagc caactctaaa gtatatgcaa aatttggtgt agaaatctat
    12301 gtagcagcta aaaaaggtga tccagatcca gaatcaaact cagctttgaa attcgttatc
    12361 gaccgtgcta aacaagccca agtgccaaaa cacattatcg ataaagcgat tgataaagcc
    12421 aaaggaaaca cagacgaaac ctttacagaa ggacgttacg aaggttttgg gccaaatggc
    12481 tctatgctaa ttgtggatac tttgacttct aacgttaacc gtacagcagc caatgtccgt
    12541 gcagcctttg gtaaaaacgg cggaaacatg ggcgcttcag gttctgtttc ttacctcttt
    12601 gacaacaaag gtgttattgt atttggaggt gaagatgcgg acgcagtctt tgagcaattg
    12661 ctcgaagcgg atgtggatgt ggatgacgta gaagcacaag aaggtacaat cacagtttac
    12721 acagcgccaa ctgaccttca caaggctatc gttgccctcc gtgagtctgg tattgaagaa
    12781 ttccaagtga ctgaattgga aatgattcct cagtcagaag tggaattgtc aggcgaagac
    12841 cttgaaacct ttgaaaaact ttacagcgtt cttgaagacg acgaagacgt ccaaaagatt
    12901 tatacgaacg tagatgggtt ttaatttaac ctatagaaca tgatcctaag tgagaaaatc
    12961 acttgggatt tttttaatca agaaaatagt tctcatagaa atttaattat tctccagaga
    13021 actattttta tttagaaggg ggagattatg gataaaccga tgttagtctt taagcgtttt
    13081 ggtcatcaaa ttcacctgat ggtgcaaaag gaagccaaac gttgcggcat tgaatttatg
    13141 ggtgggccgc aaggtcaggt tgtgcgtttt ttggataatc gcgagaaaaa ccaagacttg
    13201 gtcttgatta aagatatcga gcaggaactc aatattacca agtctgttgc tagtaatcta
    13261 gttaagcgta tagtgcaaaa tggtttggtg gaattggagg cgagtcctgt tgataagcgg
    13321 gctaagtttg ttcgtctgac ggacaaagca cgttctcaga tgcaacaggt taaggctttt
    13381 tttgaacgca tagacaagca gttgatggaa gacattgatg aagatgaatt actgattttc
    13441 gagaaggttc tcggtcaact acaggcaaaa tatcaaggga ataggaggag agaataaaga
    13501 aattagccaa aagaattagt agaaaagaat gggggatgat tttactagcc attctcttta
    13561 cttgcttttc ggtctatcta gagttggaag tgccgaccta tatctcgaaa attacggatt
    13621 tgctaggtag tcaagaaact aatttagatg agttgtggca gccggcaagc atgatgatgg
    13681 gaatgtcctt tcttgccttc ttgtccgtag ttgcagttgg attttttgca tcccgagtgg
    13741 cggcttctta tactagtagg ctgagaagtg atatttttaa ccgagttttg gattactcgc
    13801 agacagagat taagaaattt tcaattccta gcctcttgac gcgtactacc aatgacatta
    13861 ctcaagttca aatgttgatt actatgggct tgcaagcggt aacgcgtggt tcaattatgg
    13921 ctatctgggc tattgggaag attttaggtc attcagaata ctggctctgg cccgtacttg
    13981 tggcagtgat tatcaacgtc ctgatgacga ccgttttgat gacgctagcc tttccaaaac
    14041 agtccttgat tcaggggctg acagataaac tgaacagtat cactcgtgag agtttaacag
    14101 gtattcgtgt cgttcgtgcc tacaatgcag aggattatca aaatgaaaaa tttgcagcag
    14161 taaatgatga attgacccgt ttgaatttgt ttgtcaaccg tcttatggct attttgaatc
    14221 ctatcatgat ggggatttca agtggtttga gtgtggcgat ttactggatt ggggcctatg
    14281 tgattaacga cgctgctccg atagcgcgtc tgcctctctt tagtgacatg attgttttca
    14341 tgtcttatgc catgtaggtt gtcatgggct tccttctcat gggagcactc ttcatcgttc
    14401 ttccccgaac tatggtctct gctaagcgga ttaatcaagt tttagatttg cattcttcta
    14461 tccaaaaacc tgttcaagtg cagctgactg atgaaaactt caaaggtcag gtcgagttta
    14521 aggatgtgac cttccgctat gcggcaaatt cggaggcagt tattgaacat gttagattta
    14581 aagcagaaac tggtcaaaca gtggccttta ttgggtcaac aggttctggt aaatcaactc
    14641 tggtcaatct gattccacgt ttctacgacg tgtcagcagg agaaattctg gtggacggtg
    14701 tcaatgttca agactatgac ttctctgcga cagctcatgc tggtcaaaag gttgccattg
    14761 ttgggccgac tgggactggt aagacaacca ttgtcaatct tttgatgaaa ttctatgaga
    14821 ttgataaggg aagtattcac attgatggtg tggataccaa ggctatgacg cgttcagaag
    14881 tgcatgatgc cttttcaatg gtcttgcagg atacctggct ctttgaagga actattcgag
    14941 acaatctcat ctataatcaa atagggatta gtgatgaacg aatgatggaa gctagtaagg
    15001 ctgtgggaat tcaccacttt attatgacct tgccagatgg ctatgatacc atcttggatg
    15061 acaccgtgac cttgtctgta ggacaaaaac aactattgac tattgcttgt gcccttctta
    15121 aggatgcatc gcttttgatt ttggatgagg cgacttcttc tgttgacaca cggacagagg
    15181 aattgatcca aaaagccatg gaccgtttga tggaaggacg cacatccttt gtcattgccc
    15241 accgcttgtc aaccatccga aatgcagact tgatcttggt catgaaagat ggaaatatca
    15301 tcgagcaagg caactatgag gaactgatgg cgcaaggtgg cttctacgct gacttgtaca
    15361 atagtcaatt tacagaagat gaagcagaag aataaatcaa aaaaggcttg acggccttct
    15421 ttttcttatt tatactagta cacatagaaa gagagaagta tgagtcagaa attatacaat
    15481 atgaaatttg ctgctgtcta cttagccttg attgcaaaag ttgagcgaaa gggtgaaaag
    15541 gcagagtcag ttcaccaagt gaccagttgg ttgacagggt atgaagtgag tgacgttctt
    15601 gcttgtctgg atagggatgt tacttacgga gatttttttc tacaagcacc atattatgtc
    15661 cctgaacgaa ttgcaattac agggaagatt tgcggtgtcc gtattgagga aattgatgat
    15721 cctctgatgc aggaaataca tcgcttggac aagctagtgg attggcttgc caaggggaaa
    15781 acatctcaac aagttctaga aaagtatgag aagcataaat gaaaaattat caagaatggt
    15841 atcgaaatat cagctccaga ctaactagtc gtccaattct tttattccta ttacgcagtt
    15901 tcaatcgttt gatgacagtc gccatgcccc tggtctatct gatcttgcta gtcaccactt
    15961 acctgcaact aggacttggt cagcaagttg gggtttatgt gcttattcct gcatcaggtt
    16021 ttgtggcctt gtccctgttt cgtaagaaaa tcaatcaccc gagaccttat gaaacttggg
    16081 atatctgtcc ccttcttgat aaggatagtt cgggacggtc gatgcccagt cgccatgtct
    16141 tttctgcaac tatcatctcc atggcctgtc tgcatgctag tctacctatt ggcttagtat
    16201 gcttgatctt ttcagctttg ctggggttgg tgagggtttt agggggtgtt cattatccca
    16261 aggatgtctt ggttggctat gcttgtggtc tggtgtgggg attccttttc ttcctattct
    16321 gacatgtaag ttaagctagt cctacaacca cttactgctt caaattgacc acttgctttt
    16381 ttgcccttgt attcctaact tagctttgat atagtagagt cagaaaggag atgtgatgaa
    16441 gttacgaatt gagattgacg gcaatttaga ggagactgaa attgtcatca agacccccac
    16501 tttgacagat gaaattgcag acttgcaacg gctcttgcaa gagtcaaagg ctccgaggtt
    16561 gactttttac aaggggacag gtgaatatta tctagacctg tcagaaattc tcttctttga
    16621 aacagaaggg agcaagatct acgctcataa ccagaaggaa gcttatgagg ttcgcctcaa
    16681 gctctatgag ttggagtcta tcttgcctcg ctattttaat cgagtttcca agtcaacgat
    16741 cgcaaacatc cgtcagattt actcagtgga caagtccttt tcaggaacgg gcaccatttc
    16801 cttttatcag acgcacaagg aggttcatgt ctcacggcat taccaatccc tcctaaaaga
    16861 aaatctaaga aacatgaggt aataagatga aaaagaaagc atttggtatt gtgttacttg
    16921 tactagcagc tttaatatta gtacaaggaa attttggaat cccttctcta ggagggcaca
    16981 tttggccctt gattggtatt gctttttttg cctaccaatc agttggagct ttgttgcgtc
    17041 gccacttaac ttcagcctct tttacagctc tagtagcctt aatgattgct aaccactttt
    17101 atggcatttt accgattcca aaccagacac taatctgggc aggagttcta atcgttctcg
    17161 gagtaaatat gttgactcat tctaacagaa cttggaatgg gaaaaaatgg tggtatgatg
    17221 gtgaaaaaaa cattcttata gataaggaag ttgcttttgg gacagggact ttctacaagc
    17281 aagaccaaga attggtagaa gaccaagtag aagttggttt tggcaatgca aaaatctact
    17341 atgacaatgc agagatgtta ggtgattttg caactttaaa tattgaagta gcttttggta
    17401 atgcaactgt ctatgttccg caacactggt gtgtcgattt gaaagtagaa acatcctttg
    17461 gtgcagccaa ggcggacgct cctgtagcgc caacaagcaa aaccttgatt attcgtggag
    17521 acgtggcctt tgggaagttg gagcttgtct acgttaaata aaaaaatctt cacttaaacc
    17581 atcaaaatag acgtactaag agtaggaaat tgatgccttg ctctgatttc agttctatgg
    17641 ttgttagact ttaaaaaatg aaatgttgcc tttaaaagtt gtatattttt cgatattttg
    17701 actcttacgt ttgatgtatc tatgtcctac agcgtggatg atgtagtgta aaatgcttta
    17761 aaaaaaatga atgatattgg acagtttttt tgaactttta attgctcagg agccatgaaa
    17821 gcaagcgctt gggtttatga caagggagaa tggtattatg taagttcttc tggttccatg
    17881 attgcgaatg attgggtcaa agacaatggc aagtagtatt atctggcttc atcaggtaag
    17941 atgcttcgca atacctacac acctgatagt tactacgttg gcaacttagg tgcctggcaa
    18001 taagaataat actcttcgaa aatctcttca aaccacgtca gcttcatcca caacctcaaa
    18061 acagtgtttt gagctgactt cgtcagttct atctacaacc tcaaagcagt gctttgagca
    18121 gcctgcggct agcttcctag tttggtcttt gattttcatt gagtataaga agtccttttc
    18181 cttaaaggaa gaggcttttt acttgctttt ttgctgtttc ctcatttgtc ctaaagcctt
    18241 ttttgtgtta aaatgaatgg tatgaaagct aaaaaaatgt ggatggcagg cttggctctg
    18301 ctaggtattg gaagccttgc tcttgctacg aaaaaagttg cagatgaccg taagctcatg
    18361 aagactcagg aagagttgac agagattgtg cgagaccatt tttccgacat gggggaaatt
    18421 gcgaccctct atgttcaagt ttacgaaagc agtctggaga gcttggttgg tggcgtcatt
    18481 tttgaggatg gccgtcatta tacctttgtc tatgaaaatg aagacctagt ctatgaggag
    18541 gaagtcttat gatacagcca gcaagtttag aagaattagc atctttagtg gaaaaagcgg
    18601 gcaagaaggt cttccttttt gtggcagact ggtgtggcga ttgtcgttat atttatcctg
    18661 ccttaccaga gattgaagag accaatccag agttcacctt tattcgaatg gaccgagatc
    18721 agtatatgga tttggccaaa ctctgggatg tttacggaat tcctagcctt gttgttctag
    18781 aaaaggacaa ggaaatcggt cgttttgtca atcgcgaccg taaaagtaag gagcaaatta
    18841 acgatttttt agcaggattg aaataggaga aaaaggaaac aatgattttt acgtataaca
    18901 aagaacatgt cggtgatgtc cttatggtca tcgtgaaaaa tagcggagat gccaaactga
    18961 atgtggaacg caaaggcaag gtagcccgtg ttttcctcaa agaaaatggg gaaacagtag
    19021 cttggaacat ttttgaggtt tcgagcttgt ttgaaattgc agagcgcggt caagtctttt
    19081 tatcagatga gcaagtcgct cgtttgaacc aagaattaca ggcggaaggt tttacagaag
    19141 aaattgttaa tgataaggaa cctaagtttg ttgttggtga aattgtcgag atggtagctc
    19201 atccagacag tgaccacctc aacatctgcc aagttgcagt cgcaagtgac aagatagtgc
    19261 aaatcgttgc aggagcacct aatgcgcgtg ttgggttgaa aaccattgtg gctcttcctg
    19321 gtgccatgat gccaaaaggg aatttcattt tcccaggcga acttcgtggt gaaaagagtt
    19381 ttgggatgat gtgtagtcct cgtgaattgc atttgccaaa tgctccgcaa aaacgtgggg
    19441 tgcttgaatt atcagaagac caagttgtcg gaacaccgtt cgacccagcg aaacactgga
    19501 ctgcctagga acttgtcagc atctgataga aggaaataag atggcaaaaa atgtagtgat
    19561 tacgggagca acctcaggaa tcggtgaagc gattgcgcgt gcttatctgg agcagggtga
    19621 ggatgtcgtt ctaacaggac gacggataga cagattagaa atcctcaagt cggagtttgc
    19681 agtaagcttt ccaaatcaaa ccgtctggac ttttccacta gatgtgacgg atatggtcat
    19741 ggtgaagact gtttgctctg atattctaga aacgataggg aggattgata tcttggtcaa
    19801 caacgccgga ctggctcttg acttggctcc ctatcaagac tatgaggagt tggatatgtt
    19861 gaccatgttg gataccaatg ttaaaggtct gatggcggtt actcgctgtt tcttgccagc
    19921 aatgataaaa gtcaatcaag ggcatattat caatatgggg tcaaccgcag gaatctacgc
    19981 ctatgctggt gccgctgttt actcagctac caaggcagcg gttaagacct tttcggatgg
    20041 actgcgaatt gataccatcg caacggatat caaggtgaca accattcagc ctgggattgt
    20101 cgaaacagat ttctcaactg ttcgttttca tggtgataaa gagcgggctg cgtccgttta
    20161 ccaaggaata gaagccttgc aagctcagga tattgcagac acagtagtct atgtgaccag
    20221 tcagcctcgc cgtgttcaga ttacagatat gaccattatg gccaatcaac aggcgacagg
    20281 tttcatgatt cataaaaaat aagaaatttc ctcgaaaagt tacaaatttc tgtaactttt
    20341 tttgatttcc tacgaataga taagtaggag gaagaaaata tgtataataa agttatcttg
    20401 attgggcgtt taacgtctac accagaattg cacaaaacca ataatgacaa gtcggtagcg
    20461 cgagcaacta tcgctgtcaa ccgtcgttac aaagaccaaa acggtgaacg tgaagctgat
    20521 tttgtcaata tggtcctatg gggcaggcta gcagaaactt tggcaagcta cgcaaccaaa
    20581 ggtagtctca tttccgttga tggagaattg cgtacccgtc gctttgagaa aaatggtcag
    20641 atgaactatg taaccgaagt ccttgtgaca ggattccaac tcttagaaag tcgtgctcaa
    20701 cgtgccatgc gtgaaaataa tgcaggccaa gatttggcag atttggtctt ggaagaggaa
    20761 gaattgccat tttaatactc ttcgaaaatc tcttcaaacc acgttagctt tatccacaac
    20821 atcaaagcaa tgctttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat
    20881 tgagtataaa cattaaaaag tctgagttgg tctcaggctt tttatcttga gaaagtcaga
    20941 cttttttctt gactatttct gaccaagtga tacaatagaa ttatgaatta gcactcaagt
    21001 tcaaagagtg ctaataatat ctatctcatt atggaggaaa tcagatgttg aaaccattag
    21061 gggaccgtgt ggtcttaaaa atagaagaaa aagaacaaac cgttgggggc tttgtccttg
    21121 caggctcagc ccaagaaaaa accaaaacag ctcaagttgt ggctactgga caaggtgttc
    21181 gtaccttgaa cggtgacttg gttgctccaa gtgttaaaac tggagatcgt gtcttagttg
    21241 aagcccacgc aggtcttgat gtcaaagatg gcgatgaaaa gtacatcatc gtaggcgaag
    21301 ctaacatctt ggcaatcatt gaggaataga aggagaaagt aagtatgtca aaagaaatta
    21361 aattttcatc agatgcccgt tcagccatgg ttcgtggtgt cgatatcctt gcagacactg
    21421 ttaaagtaac cttgggacca aaaggtcgca atgtcgttct tgaaaagtca ttcggttcac
    21481 ccttgattac caatgacggt gtgaccattg ccaaagaaat cgaattggaa gaccattttg
    21541 aaaatatggg tgctaagtta gtatcagaag tagcttctaa aaccaatgat atcgcaggtg
    21601 acgggactac gactgcgaca gtcttgaccc aagctatcgt ccgtgaagga atcaaaaacg
    21661 tcacagcagg tgcaaatcca atcggtattc gtcgtgggat tgaaacagca gttgccgcag
    21721 cagttgaagc tttgaaaaac aacgccatcc ctgttgccaa taaagaagct atcgctcaag
    21781 ttgcagccgt atcttctcgt tctgaaaaag ttggtgagta catctctgaa gcaatggaaa
    21841 aagttggcaa agacggtgtc atcaccatcg aagagtcacg tggtatggaa acagagcttg
    21901 aagtcgtaga aggaatgcag tttgaccgtg gttacctttc acagtacatg gtgacagata
    21961 gcgaaaaaat ggtggctgac cttgaaaatc cgtacatttt gattacagac aagaaaattt
    22021 ccaatatcca agaaatcttg ccacttttgg aaagcattct ccaaagcaat cgtccactct
    22081 tgattattgc ggatgatgtg gatggtgagg ctcttccaac tcttgttttg aacaagattc
    22141 gtggaacctt caacgtagta gcagtcaagg cacctggttt tggtgaccgt cgcaaagcca
    22201 tgcttgaaga tatcgccatc ttaacaggcg gaacagttat cacagaagac cttggtcttg
    22261 agttgaaaga tgcgacaatt gaagctcttg gtcaagcagc gagagtgacc gtggacaaag
    22321 atagtacggt tattgtagaa ggtgcaggaa atcctgaagc gatttctcac cgtgttgcgg
    22381 ttatcaagtc tcaaatcgaa actacaactt ctgaatttga ccgtgaaaaa ttgcaagaac
    22441 gcttggccaa attgtcaggt ggtgtagcgg ttattaaggt cggagccgca actgaaactg
    22501 agttgaaaga aatgaaactc cgcattgaag atgccctcaa cgctactcgt gcagctgttg
    22561 aagaaggtat tgttgcaggt ggtggaacag ctcttgccaa tgtgattcca gctgttgcta
    22621 ccttggaatt gacaggagat gaagcaacag gacgtaatat tgttctccgt gctttggaag
    22681 aacctgttcg tcaaattgct cacaatgcag gatttgaagg atctatcgtt atcgatcgtt
    22741 tgaaaaatgc tgagcttggt ataggattca acgcagcaac tggcgagtgg gttaacatga
    22801 ttgatcaagg tatcattgat ccagttaaag tgagtcgttc agccctacaa aatgcagcat
    22861 ctgtagccag cttgattttg acaacagaag cagtcgtagc caataaacca gaaccagtag
    22921 ccccagctcc agcaatggat ccaagcatga tgggcgggat gatgtaagct ttctatagaa
    22981 aacaacttat aaaaaacaca aaaggaggga atgactaacc cttcttttta taatattcac
    23041 ttctaaattg atttgagctc tcctaactta tatgataaaa taagactaga aaaaggagaa
    23101 gaacatgatc gatgtagaag aaattctgtg caagatgacc cccaatcaga agattaatta
    23161 tgaccgtgtc atgcagaaaa tggtacaagc atgggagaaa aatgagcagc ggccaaccat
    23221 tctcgtgcat gtttgctgtg ccccttgtag tacctataca ctagaatatt tgaccaagta
    23281 tgcagatgtg accatctatt ttgtcaattc taatatccat ctcaaggtag aataccataa
    23341 gcgggtctat gtcaccaaga aatttgttag tgattttaat gagcggacag gaaatacggt
    23401 tcagtaccta gaagctccct acgaacccaa ttaataccga aaactagtta ggggactaga
    23461 ggaggagccc gaaggtggcg accgttgcaa ggtttgtttt gactaccgac tggataaaac
    23521 agcgcaagtg gctatggact tgggctttga ctactttggt tcagccttga ccatcagtcc
    23581 tcataagaat tctcaaacta tcaatagcat cggaatcgat gtgcaaaaaa tttacacgac
    23641 ccactatctt cccagcaatt tcaagaaaaa tcaaggctac aaacgttcag tagagatgtg
    23701 tgaggagtat gatatctatc gtcaatgtta ttgtggctgc gtctatgcag cccaagccca
    23761 gaatattgac ctggtttaag ttaagaagga cgccacagca tgcttgttgg ataaggatgt
    23821 tgagaaagac tattctcata tcaaatttat agtagattga aactagaata gtacaccttt
    23881 acttctaaaa cattgttaga aatcgatttg actgtcctga ccaatttgtc ctgttcttat
    23941 ttcattttat tatactgtta cgaaattaga tatataaatg aaaacttgcc tcaaggtagg
    24001 ttttttgcta gtagaaaagc gatagacaga aattgttgga ctcttaaaaa aatgaagttt
    24061 tgctcaaaag agctttttaa attaaaacga gcaattatca gttcaaatct gtttcaaaag
    24121 aagaacggat aaattaatcg atgctttgtt tttgagttag gaagttaagc atgccaaact
    24181 gagtcgtagg aataaatttc tttatagaaa tgtgttacaa ctttgctata acggaatatt
    24241 ccttttttgc atttatacaa cttatttaac actatcttta ttcttgtgat ataatgccaa
    24301 attatagagt ggaggtcatt taaaatgatt gataaagtaa ttgaacaata taaaagtcat
    24361 gataatcttg atattcgagt agaattgcat aagaagtatt caaaaaataa attgggattt
    24421 aataattgga tattttctaa ctaccaaatc actgatgaaa taaaggttct agaattagga
    24481 tgtggtacag gagaactgtg gaaaagcaat agtgattcta tagataaaat gaagcagttg
    24541 attgttacag atttttctaa agatatggta aaatcaacga agtcagtgat tggaaataga
    24601 gacaatgtca actatgagat aatggatatt caaaaaattt cttttgagaa tgaaactttt
    24661 gatattgtta ttgctaatat gcttctacat catgtgaatg atattcctaa agctctctct
    24721 gaggtgaata gagtcttaaa aaccgaaggc attttttact gtgctacatt tggtgaaaat
    24781 ggagttgtaa attatttggc aagtttattt aaagatgagg ttaatcaaga tttagaaaat
    24841 agaacgttta ctttacaaaa tggtaaaagg tacctgagta ggtattttaa ctctgtcgat
    24901 acattactct atgatgatga gttacaggta actagtatag atgacctagt taaatacatc
    24961 caatcgttta aaggaatttc agaaataggt tcactagaag aggaaataat acgtaaaaga
    25021 ttggaaagtg agtttaataa tggtatgttg atcattccta aagaatatgg tatgtttatc
    25081 gctcgaaaag aaagttaagg gaatgaaagt gtgaaaaatt acggagaagc ttttcgatat
    25141 tttagaaaat taaacggata ttctttagag tatgctgcag ctgattctat atcaaaatct
    25201 caactttcta gatttgaaag gggagaaaat gaaatttctc tttcaacatt ttttgaatta
    25261 ttatcaaata tcaatgtttc gatagagaat ttttgtaatc acctagaaca ttataaaaga
    25321 tcggagcgtg atgatttttt ggttaattta tctccaaatt tttatagttt gaatattaaa
    25381 ggattggagg taataaaaaa tgagtaacaa aaactttttg agaagagtgg ggaaaaaact
    25441 cataaaataa atacaattat ggttcaggga ttatgaaatc agctagattg taatcatgta
    25501 gttagtagag atgatctaaa tttagtatat gactatttat tccagaagga acgatgggag
    25561 tcctatgaga taacgctgat tggtaattta tatcatcttt ttgaaataga ttatatttac
    25621 atggtcggaa aagaaatact agagcgtaca cattattacg aaaaaatcgg caagaataga
    25681 catttagttg tgtcagcttg tttaaatttt tggttctgtt gccttgaaaa ttcacatcta
    25741 atatatgcag actactttga aatgaaatta caaaaattat taaaagatga cacaaaagtt
    25801 tttgaaaaat ctacattcaa atttgtagaa ggatataaaa tatacct
//
LOCUS       DAVDFK010000025        25515 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.25, whole genome shotgun sequence.
ACCESSION   DAVDFK010000025 DAVDFK010000000
VERSION     DAVDFK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.25"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            15..1076
                     /gene="dinB"
                     /locus_tag="VUR04_001356"
     CDS             15..1076
                     /gene="dinB"
                     /locus_tag="VUR04_001356"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET5341243.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(1223..2068)
                     /locus_tag="VUR04_001357"
     CDS             complement(1223..2068)
                     /locus_tag="VUR04_001357"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET5341244.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            2324..3113
                     /locus_tag="VUR04_001358"
                     /pseudo
     CDS             2324..3113
                     /locus_tag="VUR04_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3492..5381)
                     /locus_tag="VUR04_001359"
     CDS             complement(3492..5381)
                     /locus_tag="VUR04_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET5341245.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYHWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFDYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            5519..7084
                     /locus_tag="VUR04_001360"
     CDS             5519..7084
                     /locus_tag="VUR04_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET5341246.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            7084..7824
                     /locus_tag="VUR04_001361"
     CDS             7084..7824
                     /locus_tag="VUR04_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5341247.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKTKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(7933..8148)
                     /locus_tag="VUR04_001362"
     CDS             complement(7933..8148)
                     /locus_tag="VUR04_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341248.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(9021..10271)
                     /gene="ilvA"
                     /locus_tag="VUR04_001363"
     CDS             complement(9021..10271)
                     /gene="ilvA"
                     /locus_tag="VUR04_001363"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET5341249.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(10321..10677)
                     /locus_tag="VUR04_001364"
     CDS             complement(10321..10677)
                     /locus_tag="VUR04_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET5341250.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(10915..11151)
                     /locus_tag="VUR04_001365"
     CDS             complement(10915..11151)
                     /locus_tag="VUR04_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341251.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(11258..12280)
                     /gene="ilvC"
                     /locus_tag="VUR04_001366"
     CDS             complement(11258..12280)
                     /gene="ilvC"
                     /locus_tag="VUR04_001366"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET5341252.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRNSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(12346..12822)
                     /gene="ilvN"
                     /locus_tag="VUR04_001367"
     CDS             complement(12346..12822)
                     /gene="ilvN"
                     /locus_tag="VUR04_001367"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET5341253.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(12815..14515)
                     /locus_tag="VUR04_001368"
     CDS             complement(12815..14515)
                     /locus_tag="VUR04_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET5341254.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(14716..16383)
                     /locus_tag="VUR04_001369"
     CDS             complement(14716..16383)
                     /locus_tag="VUR04_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET5341255.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(16386..16751)
                     /locus_tag="VUR04_001370"
     CDS             complement(16386..16751)
                     /locus_tag="VUR04_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5341256.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(16908..17096)
                     /locus_tag="VUR04_001371"
     CDS             complement(16908..17096)
                     /locus_tag="VUR04_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET5341257.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(17212..17388)
                     /locus_tag="VUR04_001372"
     CDS             complement(17212..17388)
                     /locus_tag="VUR04_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET5341258.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(17499..17696)
                     /locus_tag="VUR04_001373"
     CDS             complement(17499..17696)
                     /locus_tag="VUR04_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET5341259.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(17951..19495)
                     /locus_tag="VUR04_001374"
     CDS             complement(17951..19495)
                     /locus_tag="VUR04_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET5341260.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYDQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            19708..20010
                     /gene="gatC"
                     /locus_tag="VUR04_001375"
     CDS             19708..20010
                     /gene="gatC"
                     /locus_tag="VUR04_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET5341261.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTNRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            20010..21476
                     /gene="gatA"
                     /locus_tag="VUR04_001376"
     CDS             20010..21476
                     /gene="gatA"
                     /locus_tag="VUR04_001376"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET5341262.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN"
     gene            21476..22918
                     /gene="gatB"
                     /locus_tag="VUR04_001377"
     CDS             21476..22918
                     /gene="gatB"
                     /locus_tag="VUR04_001377"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET5341263.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            23047..23607
                     /gene="efp"
                     /locus_tag="VUR04_001378"
     CDS             23047..23607
                     /gene="efp"
                     /locus_tag="VUR04_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET5341264.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            23629..24018
                     /locus_tag="VUR04_001379"
     CDS             23629..24018
                     /locus_tag="VUR04_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5341265.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            24011..24433
                     /gene="nusB"
                     /locus_tag="VUR04_001380"
     CDS             24011..24433
                     /gene="nusB"
                     /locus_tag="VUR04_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET5341266.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGIQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(24482..24859)
                     /locus_tag="VUR04_001381"
     CDS             complement(24482..24859)
                     /locus_tag="VUR04_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5341267.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(25222..25407)
                     /gene="briC"
                     /locus_tag="VUR04_001382"
     CDS             complement(25222..25407)
                     /gene="briC"
                     /locus_tag="VUR04_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET5341268.1"
                     /translation="MTGTNTFTILSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
BASE COUNT         7732 a         5699 c         4654 g         7430 t
ORIGIN      
        1 aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc
       61 atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag
      121 gaaaacctgt cattattgga agcgaccctc ggcaaacagg tggacgggga gtcgtttcta
      181 cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt
      241 atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg
      301 gactccagat tcgagctatt tttaagcgct atacagattt gattgaaccc atgagcattg
      361 acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg
      421 ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttcc gcaggcgttt
      481 cttacaacaa attcttagct aaaatggcga gtgattatca aaaaccacat ggtttgacag
      541 tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg
      601 gagtaggaaa aaagacagta gaacgtcttc atcaaatggg cgtttttact ggtgctgatt
      661 tacttgaagt tcctgaggtg accctaatag accgttttgg tagactaggc tatgatctgt
      721 atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa
      781 tcggcaagga gaaaacctac gggaagattc tccgtgctga ggaagatatc aaaaaagagc
      841 tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa gctggaaaaa
      901 ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga aaaagtcttg
      961 ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc tatgaagaat
     1021 taagcgagaa agaaagaggt gtccgcctat tggggattac cctgactgga ttttaaagct
     1081 caatgaaaat caaagagcaa actaggaagc tagtcgcagg ctgctcaaaa cactgttttg
     1141 aggttgcaga taaagctgac gcggtttgaa gagattttct aagagtataa aaccttgaag
     1201 agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa agtagcaaaa
     1261 cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc
     1321 tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc gcgaccaaga
     1381 gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg aaaatcttta
     1441 aggcactagc tccaaacata acgggaatcc caagatagaa ggtaaattct gtcacaactg
     1501 aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg ctagtccctg
     1561 gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa ggaagcttgt
     1621 ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc aaatagatga
     1681 aggcaacccc gtagataatc aacatgagag caactgaaac catgttatgg aagtgggtat
     1741 caaaccaatc atcaaattta aagacaccaa gtaaaggcaa agtggcaatc aagaccttca
     1801 accatagtct ccaagtctta cgaacttcct gtttgtcctt agtcggttta aaaggattga
     1861 gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc acgacattaa
     1921 acatggacat aaaggcttca ttttgatttt ggtattggat aaactcctct gctaaaatca
     1981 agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga
     2041 tagattttaa aatttcaata agatacatat atttctcctt atattatatt taacgcagtt
     2101 agctactgcc aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc
     2161 ctccaatcgc ttgacgattt ccgaaagggt ctaaccacag ctttttgttt caattggtaa
     2221 tgagtttgat aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg
     2281 gataaccaag tagacttgaa atactatatc tggaggtact cccatgcttt atgtgggcat
     2341 tgatgtcgct aaaaataaac acgatgttac agccttgaat gttcgaggaa aactgttctt
     2401 aaaccactca ctttttcaaa taataaagct ggttttgaac tcttagatct gtcttttcga
     2461 cagctcaacc aagactgtct catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa
     2521 tttcaacacg ataatcggca agtagaacta aaaatactgg ctagacatat tcatcgtctc
     2581 aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat catctttcct
     2641 gagttggata aaatcgttgg aaagcattca gaatatacct accaactctt gacacgctac
     2701 cctaatcctc agaaaaggat tgaggcagga tttgataagc tgatagaaat taagcattga
     2761 ccgcttctaa aattcaggat atcctctcag tcgcacctcg ttctatcgga acaacatctc
     2821 ctgctcgtga attcgaaatc atcgaaatca tcaaacatta caagagactc attgacaagg
     2881 cggaaacatg tgtcaatgac ttgatggctg agttcaactc ggtcatcacg acggttactg
     2941 ggattggggg tcgtttaggg gcggtcattt tagccgagat tcgaaatatt catgcctttg
     3001 ataatcctgc tcaattacaa gctttcgctg gactggattc ttctatttat cagtcaggtc
     3061 agattgattt agcaggaaga atggtcaaac ggggttcccc tcatctgcgg taggtactca
     3121 tacaagctgc caaagcatgc cctcgctttt cacctgcttt caagacctat cttaagacta
     3181 agttagaaca aggaaaacat tacaatgtag ccatcatcca ccttgcaaaa aaacttatcc
     3241 gaaccctgtt ttatatccta aaaaagagct gccatttgac gaacaaaaag tgatgtaatt
     3301 tctgaaatta acacaggatt acctttgaaa aaatggactt tttcaagggc tttttgccgt
     3361 gctctaaaat catcgccaaa tcatcaaatt gaaataagaa atagtttaga taaaactatt
     3421 gacttttctt atagtttgtc tttcttctat cttccattat atcatacttt ttcagtctat
     3481 ggtagctctc tttaaaaggc tccgatactg ccgccacctc cgcctccaga gaagccaccg
     3541 ccagaacttc cacttccaga agatacggag taggtacttg ctgtatttgc gacactagca
     3601 taatggctca tttgcgcgct tgaatgataa aacatactgt gccagccata agctacatag
     3661 agattgatat ctggattttc aacttgaatc tgatgaacct tcatcaaatg actaaccttg
     3721 tccgcatagt caaataaggt tgcatagacc aagagacgat tccaaacaac aatactttcc
     3781 aattcagcct tatccagtcg tgcaatctca cgtaacatat tttcaaaact ggtccagaga
     3841 tagtagacct cagctcccgc ttcatttaga acaccatcac gattatctag tcgaagcttc
     3901 caatgataga aaacagacaa aactaaccct agaaaaccaa gtattggcaa agggaggtaa
     3961 agatagccat gaacgtctaa actgtacaag aacaaaccaa atccgataaa taggggcaag
     4021 atagtcaaga cacccatacc cacttgcaaa gtcttttcca aaccagttaa aggacgatag
     4081 taatctggga gcccccagaa ggaaactcgt tttctcactc cttcttgcat ctggttcaat
     4141 acctcttcaa aagaagattt gagttgaagc cctcttgctt gaatccgttt ttcatcagaa
     4201 actttggctc tacgataaag actatcagat accttgtaat ccgcaaacaa attggaaaga
     4261 gtttcttctt ttttacctga aaaagctaga tttaggcagt ctttctcaaa gcttgacaaa
     4321 ccatcttctt ttactagcct caaaccaact gcatctcctt ctgaaatgat agagacattc
     4381 ccacggtcta tcacatctag caaggtagct tgaataagtt gatcaaaggt gaattttcca
     4441 gctcccttga ccaagggact cacttcctcc aaggaggtcg agtagactgc ttctgataaa
     4501 accataggct ctaattccat tggtggttca tagagacgat gatttttggc atatttgact
     4561 gaaggagtgg tctttcttct ataaataaaa tagaagcaga cactcaataa caaggagata
     4621 gaaagtatcg aagggaggac ccaagtaacg agttgtttac tctgatcttt ttctctaaca
     4681 atcgagtctt ctatcttatt aaactcttct aaacgattcc ctttcaagcc ctgatcccta
     4741 gcgctagcaa aatcggtccg aggccaatag gcatgcaact caactccacg cttagccgga
     4801 agattgtcta aacggatagt ataatcaagg ttactctttt caatcgttcc ctctctaaaa
     4861 agtttccctg tatggaaaaa gagtttttca gcccccttgt ctccccttac atgaaattca
     4921 aacttttcaa tagactctga actatctgtc agaggttgcc aatttaattc agcgatatca
     4981 tcataaagga aaagtaaatt ttttaagttc cagacgaggt caacttcaac tatgtcgccc
     5041 tcctgacctg gattatagac tctcacagta taaccatccg cttcttctgt tacttcgcta
     5101 gtcacatctg ctagttctgc accgtttttc gcggcctgaa cctttggatg agggtcaatg
     5161 tcaaacccgc taggcatctt accagcacgt ccaagtccca cgatttgtcc cttaaagtcc
     5221 tcctcaaact gataaactat cttttgtcta aattctgccg tattgtctgc atgaatatac
     5281 aaatcacctt gataagagtt tatcttaaaa tcaatggcga aaacagaaag tggcagaagg
     5341 caaaacaagc caaacatcag taagaaaaaa gtttttttca tcaattaagc ccccttttta
     5401 tctttcttat cattatagca ttttttcgta agtaaaggct tacttatgtt gaaaaattac
     5461 gcatttttcg ataaaatagg agacagttat tttttaatag atcagaatag gagaaatcat
     5521 gagaaaaata tacttatcta ttttcacaag tctcttgctg atgctaggac ttgtcaatgt
     5581 tgctcaagcc gatgaatatt tacgcatcgg tatggaagca gcatatgctc cctttaactg
     5641 gacccaggat gatgatagca acggagctgt caaaatcgat gggaccaatc agtatgccaa
     5701 cggatacgat gttcaaatcg ccaagaaaat cgctaaggac ttaggtaaag aacctttggt
     5761 tgttaaaacc aagtgggaag gtctagtccc tgcccttact tctggtaaga ttgacatgat
     5821 tatcgcaggt atgagtccaa ctgcagaacg caaacaagaa attgcctttt cgagcagtta
     5881 ctacactagc gaaccagttc tactggtcaa aaaagattct gcctatgcaa gtgctaaatc
     5941 tttggatgac tttaatggtg cgaaaatcac ttctcaacaa ggggtctacc tttatgactt
     6001 gattgcacaa atcacaggtg ctaaaaaaga aacagccatg ggagacttcg ctcaaatgcg
     6061 ccaagctctt gaggctggtg tcatcgacgc ctatgtttct gaacgcccag aagctctgac
     6121 tgccgaagcc gctaactcta agttcaagat ggtccaagta gaaccaggtt tcaaaactgg
     6181 ggaagaagat acagctatcg ccattggact tcgtaaaaat gacaatcgta ttagccaaat
     6241 caatgccagc attgaaacca tttcaaagga cgaccaagtt gccctgatgg atcgtatgat
     6301 caaggaacaa cctgccgaag ctacaacaac tgaagagact agcagtagtt tctttagcca
     6361 agttgctaaa attctttctg aaaactggca acaactcttg cgtggtgctg gtatcactct
     6421 tttaatctct atcgtcggaa ccatcacagg tctcattatt ggacttgcca ttggtgtttt
     6481 ccgtactgct cctctctctg aaaacaaagt catttacagc ctacaaaaac tagtcggctg
     6541 gatcctcaac gtctacattg aaattttccg tggtacgcca atgattgttc aatcgatggt
     6601 tatctactat ggaactgccc aagctttcgg tatcaacctt gaccgtacac tggctgctat
     6661 cttcatcgtt tcaatcaata ccggtgccta catgactgaa atcgtccgtg gtggtatcct
     6721 agcagttgac aagggacaat ttgaagctgc gactgctctt ggtatgaccc ataaccagac
     6781 catgcgtaag attgtcctac ctcaggtagt ccgtaacatc ctacctgcaa ctggtaatga
     6841 atttgtcatc aatatcaaag atacatctgt attgaacgtt atctctgttg tcgaacttta
     6901 tttctcagga aataccgtgg caacacaaac ctatcaatac ttccagacat ttacaatcat
     6961 cgccgtgatt tactttgtcc tcaccttcac cgtaacacgt atcctacgat ttatcgagcg
     7021 ccgaatggac atggatacct atactacagg tgctaaccaa atgcaaacgg aggatttgaa
     7081 ataatgacac aagcaatcct tgaaattaaa cacctcaaaa aatcctatgg acaaaacgaa
     7141 gtgctaaaag acatttcact cactgtccac aagggagagg tcatctctat catcggaagc
     7201 tctggaagcg gaaaatcgac cttcctacgc tccattaacc tacttgaaac accaactgat
     7261 ggacaaatcc tttatcatgg acaaaacgtc ctcgaaaaag gctatgacct cacgcaatac
     7321 cgtgaaaagt tggggatggt tttccaatcc tttaacctct ttgaaaatct caatgttctt
     7381 gaaaacacaa tcgtcgctca gacaactgtc ctaaaacgcg aacgcacaga agctgaaaag
     7441 attgccaaag aaaacctgga aaaggtcggc atgggagaac gctactggca agccaaaaca
     7501 aaacaactct caggtggtca aaaacaacgt gtggccatcg ctcgtgccct ctccatgaat
     7561 ccggacgcta ttctctttga tgaaccaaca tcagctctcg atccagaaat ggttggagaa
     7621 gtcctcaaaa tcatgcagga cctggctcag gaaggcttga ccatgattgt cgtaacccat
     7681 gaaatggaat ttgcccgtga tgtctctcac cgtgttatct ttatggataa gggcgtgatc
     7741 gctgaagaag gtaaaccaga agacctcttc accaatccta aagaagaccg aacaaaagag
     7801 ttccttcaac gctatctcaa ataaaaagaa aaggctgcat caaccgtgca gtctttttgc
     7861 tgtcctcaaa atgaaaaggc agattctcta tctctactac ttgaaggtca agaatccgcc
     7921 gttatcaaaa gattaatctt caaatttttc ataatttttt tcatagaaat caattaggcc
     7981 tagggctgtt tcaaatgaaa tattttttac ttttgcacga ccctgcgcca gagcaatgat
     8041 agacatttca cgcgcattcg tttctttaga gatacggtag cctgtgattt tcttatcacg
     8101 aacccagcca acaactgatt ctactttttc aaagtttgac ttagccatgt ttttctccta
     8161 ttttcttctt tataatattt aattgtatac gtttttacta cttttgtcaa taaaaaaaac
     8221 atatattcaa cgaaaataat tagttcagaa ttttcttact tcctttttaa atccgataat
     8281 atatataggt tttgctagcc tctacaccat aaatatttgc taataaaaat actgtattat
     8341 taccctctta aggtgcgaaa ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag
     8401 atagcttatt tcttcgattt aagaactgaa gatgatagtt ctaaccttta gaaatccaag
     8461 ccttcactag ctcaaaaact cctatctttt ttcctcaata aatcatctga gagataggta
     8521 ttccttatat ccttcaaatt catcactcct ttggatattg aggtgctagc ctagaagcag
     8581 acacccgatt atctaaacca tccttaatag agatgacaag acagataagc tcagttaatt
     8641 acttatatat ctttttaata tggtatattt gtcaacaaaa agaaatcaaa ttatacctta
     8701 tactcaatga aaatcaaaga gcaaactagg aagctagccg caagttgctc aaaacactgt
     8761 tttgaggttg cagatagagc taacgtggtt tgaagagatt ttcgaagagt attaaagaca
     8821 gtgtgactat gcttgtcaat agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa
     8881 catcataagt gctataatga acagaagtaa gaattgcgcg ataagtttcc taaaaccata
     8941 ggaatcgtcc cctttcttca tcttcattat agcacatata catcagttgt gcaaataata
     9001 tgatattttt ttattagtcc tcagacaagc atattataaa gcgtttcatt accatttaag
     9061 ttaatataag ctggatcaaa accttccatt ctacggatca aacctgcata atcatgctta
     9121 tctgctaaag cgatcccaat taatactggg cctgttccct tgctagctcg tttgatatac
     9181 tcaaaacgtg tgatatcatc atttggcccc aggatatcat ttacaaactc acgcaaagct
     9241 cctggacgtt gtgggaaatt gaccacaaaa taatgtttga taccatcata aatcaaggca
     9301 cgctcttcca tttctggcat acggttgata tcattatttc ctccagaaat gatacaacaa
     9361 atggttttcc ccttaatata ttcagctaaa acctctaaag aggcgatact agccgctcca
     9421 gcaggttctg cgactatccc ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat
     9481 ccctcatcga cacctaccaa agtttgaata tgttgacgag ttgcttcata ggtcaactga
     9541 cctacctttt gcacagcaat cccatcagca aatttatcaa tttccttgag ttttactgga
     9601 cctccagcct caaaggcagc tttcatggaa cgcgctccat tcgcctctac tccgataacc
     9661 tcaatctctg gacttgtttc cttgatatag gtagaaaccc cggcaatgag accgccacca
     9721 ccaacaggaa ccaagacagc atcaaaatca atcgattctt ttcgagcttc ttctaaaatc
     9781 tcataagcaa ctgttccttg acctgcttga acatgagcat catcaaaagg atcaataaag
     9841 gtacgatttt cagagactgt aaattcttga gctgctttgg ctgaggcatc aaaggtatct
     9901 ccaactagtt taatagttac aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt
     9961 tgtggcgtag taatgggcat aaagatagta gcaggaattt tcatttcatt acaagtatag
    10021 gctactccct gcgcatgatt tcccgcagaa gcgcagacta ccccacgttc acgttcttcc
    10081 ttgctgagct gggaaatggc ataataggca ccacgaattt taaaggagcg aacacgctgg
    10141 gcattttctt ttttcaaata aatcttagca ccatacttct ccgataaata atgatcgtaa
    10201 tccagtggag tattcacaac cacaccgttc aagaccttgt gagccttgat tatatctttt
    10261 gaacttaaca tataaaacct ctttttctat aaaaaacagt cactaatgac tgttttttag
    10321 ttattcatct ccgaaaactt cagtaacact ttcatggtat ttatgagcca tacgaatcga
    10381 aaactcttta ggaagttcat aacgatttgt ggaaatccaa tcatataacc attctaccaa
    10441 actttcttca ctatcattac gatggaagat aaaatagttt aaaatttctt tatattctac
    10501 atcattcaaa tccaacgtgt ctacaaattg actacgagga acaaaattag aatctaattt
    10561 tcttagttga tctgtcaatt ctcccaattg taaatccaac tgaaaaaata gtttttgcag
    10621 ttgcctatca gtttcatcac atcctgtctt gatagaaaac aaattggtaa tattcatatg
    10681 atttcaaccc ctaaataagt acatctaata tcccacgaat agctgaagct aaagttttcg
    10741 cagtccagtc atttaaaccc gattctttca atccagatgc aataatttgc tctatttgat
    10801 ataaaccgcc atctatcgtc tcatttattc tgcgaagagg accttcaata taggataaag
    10861 cttctccgaa tctaacagct gatttaggtc ctaatgattt accaactata tttgttaatg
    10921 ttttttattt ctcaaaatcc atttcgctat ataacgagca gatttagtcg caccagctct
    10981 ctcaaacgga gaatgaattt caagaccttc ttctctagct atttgtgcca atttgaagaa
    11041 ttgttcaaag gtcatatgca acctaccatc ttcaaaatta gcatcatcat aaatgttaat
    11101 tacagcattt tcatcatacg accaatctgc tttattttgg tctgctagca ctattaccga
    11161 cggtgtaatt acattataca actagaacca ataataacga tgcaattttt ctcataatct
    11221 ttttcataaa atcatctcca gcgctatata tttctaatta gttatagatt ttgaatgcat
    11281 catcgtcgtt tttaccaaca aatggcattg ctttacgcaa ttctgcacca actttttcaa
    11341 tttcaaggtt agctgcttgt tcacggtaag cagtcaattt tggacgtcca gctttatagt
    11401 catttacaaa gtcatttgca aatttaccat tttggatgtc tgccaagaca gccttcatat
    11461 tttctttaac ttgttcagtg attacacgtg gacctgatac atagtcaccg tattcagcag
    11521 tgtttgaaat agattgacgc attttcttga atccaccttc gtagatcaag tcaacgatca
    11581 atttcatttc gtgaagaact tcaaagtaag ccaattctgg agcgtaacct gcttctgtca
    11641 agacttcgaa acctgcttcg ataagggcag tcaaaccacc acaaagtaca gcttgttcac
    11701 caaacaaatc ttcttcagtt tcttctttgt aagttgtttc aagaagacct acacgagccg
    11761 ctccaacacc tttacaccag tccatagcaa tgtttttagc atttcctgtt gcatcttggt
    11821 atactgcata aagagctgga acaccaaatc cttcttcgta agtacgacgt accaagtgtc
    11881 ccggtccttt aggagcacac atgaagacat ctacatccgc aggaactttg ataaattcaa
    11941 agtggatgtt gaaaccatgg gcaaatccaa ctgcgtttcc agcttccaag tttggagcga
    12001 tttctgcttc gtacaattct tgttgaattt cgtctggcgc caagatcatg ataacatcag
    12061 ccaacttagt agcttctact actgtgtaag tatcaaatcc atcttctttt gctttatcaa
    12121 aagatttacc tggacgtaca ccgataataa cgtcacgacc tgaattacgc aagttttgag
    12181 catgcgcatg tccttgtgaa ccataaccga taacggcgat ttttttaccg tcaagtgctg
    12241 ctactttaac atctttttca tattccattt gaactgtcat agcttttctc tcttttctat
    12301 tatttattgc cttttaggct ggtttaataa atttaagttg gatttttaat cgcgggtaaa
    12361 tccagttgca cccgttcgag caatattgcg aataccgtat gggcgaatga ctcgcaatag
    12421 ggcttcgctc ttttctgcat ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc
    12481 taccactgtt gcacggaaag gttgaataat cgctaaaatc tcagctctct tctcagctgg
    12541 cgctgacatc ttaaccaaaa tcacctcgcg ctccaaatga ggcttgtctg taatatctcg
    12601 aatgcgaatc acatcaatct gacgattgag ctgtttgatg atttgctcca cttcatcatg
    12661 agaagcaaca tcaataataa tagtgatacg cgatacattc ggatcttctg ttgctccaac
    12721 agagatgctt tcaatattaa cctgacgacg agataggaca cctgtaaagc gattgaggac
    12781 tcctgaacga ttttgtagtt ttgctgttaa cattctacgc atggaactgc acccccaaca
    12841 tctcatgatt actcttacca gccggtacca ttggtaacac ctgttcctta cgagaaatat
    12901 ctacctcaat tagcatagga acatcctcag tgatgacttc aaggtcttga gccaaggtct
    12961 caggattgtc aaacttatag tttttaatac cataagcctg cgccatcaat tggaaatcag
    13021 gaagggtatc aaagaccgac tctgatgttc tgccttcata gaaggattcc tgccactggc
    13081 gaaccattcc aagtgaatga ttgttcagca taaccacctt gattggcacc ttgtaaatat
    13141 tcaaaatagc caactcctgg ttggtcattt ggaaaccacc atccccaaca aacaagacta
    13201 cttccttatc tgggttagca attttagcac cgattgctgc tggaattcca aagcccattg
    13261 ttcccaaacc acctgaagtc actaactgac gctcattttg gtagggataa tactgagctg
    13321 tccacatttg gtgttgacca acgtctgtta ccacaatggc atctccattc gtcaattcac
    13381 caattcgttc aataactgct tgcggttgaa ccacacgctc tttcttgtca taagaacgaa
    13441 cacgattctt gtctttagtg actttctcaa tccacttttc agtattgttg tgaactgttg
    13501 gttctgctag caacatttgc aaggccttct tagcatctcc aactacagga atgtctgcac
    13561 tgataatctt gccaatctca gctgggtcaa tatcaatgtg ggcaacctta gcattcttag
    13621 cgaaagtctt aggattcccc gtcaaacggt catcgaaacg agaaccaata ctaatcataa
    13681 agtccgcttc cgtcatggca atatttgctg cgaatgaccc gtgcatgcct cccattccaa
    13741 gaaagagtgg gtgactcgtt gcaatcgttc cttgtcccaa aagactggtt accactggaa
    13801 tttgatagcg ttctgcaaat tcatttagtt ccgtagcagc ctcagcataa ctaattccac
    13861 caccagctaa caagactggc tttttagcct tggacaattg cttcaagatt ttcttgattt
    13921 gcatatcatt cggctcaaga gtcggctgat aacttggtaa attcacttct ggtgaataaa
    13981 tgaagtctgt ttctaaagca gatatgtctt ttggtaggtc aattacaact ggccctggac
    14041 ggcctgtagt tgcgatatgg acagcttccg taatgatacg cggaatatca gctgtctcac
    14101 gaacttggta attgtactta gtgattggca tggtaattcc tacgatgtct gcctcctgaa
    14161 aggcatcctt cccaatccct gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc
    14221 tatcgctcat agcatccgca atccctgtaa tggcatttgt tgctcctggt ccactagtga
    14281 cgacggcaac acccaacttt ccagttgatt tggcataacc ttcagcttca tgcaaacaac
    14341 cttgctcatg gcgccctaga atgtggcgaa tgcctttaaa attatatatc gcatcataaa
    14401 aaggcaaaac cgcaccacca ggataaccaa agatggtatc aactcctaaa tcacgaagtg
    14461 tttccaaaac taggtccgac cccgtcttag gagattctaa actgattttc tccattgttc
    14521 ccctttcttt cctcttaaaa ataacttgtt actatcatac cattttttca aaatttttca
    14581 agataaaaga agaaattttc tgaattttct attttaacgt ttatttatga atgttatttt
    14641 tgtttttatt aaaaagatac cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc
    14701 agtccttcat taatcttatt ccacactaaa taggtatggg taaacaggtt gttgaccttg
    14761 gtgaatctcg acttcaacgt cttcgaattc ttctacgatt tcttgagcga tttcattggc
    14821 aagttcttcg cttccgtctt caccgacata gaaggttacg atttcactat cttcatccaa
    14881 catatgtttc aaggtttcag tcaatgtttg gtgcatatca gggtttgaca caagaatttt
    14941 tccatccacc atacctagat tatcgttttc atggatttct aagccatcga tcgttgtatc
    15001 acgcacggct gttgtgacgc ttccgctaac gacatcgcta agagcagctg tcatacgctc
    15061 ttggttttct tcaatggact tgcttggatc aaaggcaaga agacttgtca taccttgagg
    15121 aagagtgcga gcctctacca ctactgctgg ttgctccaaa acttctgccg cagattgagc
    15181 tgccatgaag atgttcttgt tgtttggcaa gaagatgatg ttacgggcat tgacctgttc
    15241 aacagccttg ataaagtctt ctgttgaagg gttcatggtt tgaccgcctt cgataacata
    15301 atccacgcct tgagaacaga agatatctgc tagaccttta ccagccacca cagcaatcaa
    15361 agcatactct ttttcttcag ccgacttgat aacttgagta gcttctttct caacctgtgc
    15421 ttcgtgttgg ttacgcatat tgtcaacttt taccttgacc aagctaccat atttgagacc
    15481 ttcttgcata acaagtcctg gatcttctgt atgaacatgg actttgacaa tttcatcatc
    15541 gttaacaacg aggagagaat ccccaagctc atccaagtag ttacggaatt catcgtagtc
    15601 aaaatcttta gcataggttg gaccttgctt aagagctacc atgatttcag tacagtaacc
    15661 aaacgtgatg tcctcagtcg ctacgtgacc agctacagac ttatgatgct ctacattgat
    15721 catctcactc atgttggcag gagtcgctac aaagtcctca gatgcaatat attcgccagt
    15781 aagggctgaa aggaaacctt cgtagatgaa gaccaagcct tgaccacctg agtccacaac
    15841 gccaacttct ttcaatactg gaagcatgtc tggtgtttta gctagagctg ttttagcacc
    15901 ttccaaggct gcgcgcatga cttcaacagc gtcatctgtt tgctcagctt ttttcttagc
    15961 accgatagca gctccacgag aaactgttaa aatcgttcct tcaacaggtt tcatcactgc
    16021 cttataggca acttccacac ctgattggaa ggccagagcc aagtcttgac ctgttaactc
    16081 gtctttatcc ttgatagctt gggaaaatcc acggaaaagc tgagacgtaa tcactcctga
    16141 gttcccacgc gcacccatca aaagcccttt ggcaagaatg ctcgctactt ctccaactgt
    16201 agaagctggc ttgtctgcaa cttctttagc accattttca atggtcattc ccatatttgt
    16261 cccagtatct ccatctggaa ctggaaagac gtttaatgaa ttgacatatt cagcttgctt
    16321 attcaagcga gttgatgcag cctgcaccat ttcttgaaat aagctagtag taatttttga
    16381 cacggttatt ctcctacaac tttgatattt tgaatgtaga catttacagt ctgagcagta
    16441 attccaagct ggttttccaa gctaaaggca acacgctctt gaatgttttt tgacacttca
    16501 ctaatctttg ttccgtagct taacacggta tatacatcaa ctgcaatact gccatcttcg
    16561 gctgccttta cgacgacacc tttagaataa ttttccttac ctagcagggc ttggaaatta
    16621 tctttgaggg catttttact agccataccg accacaccaa aaatctcagt tgctgctcca
    16681 cctacgacgg ttgcaatcac ttcatctgtt agttcgattt gaccatcttt tgtattaatt
    16741 tttacagtca tcctttttac ctcaactagt tgatactcta ttttatcata tttcagccca
    16801 agtgtaaaag cagaatgatg tatcagcgga tatttactct atttttcaaa cgatgttata
    16861 cccacaataa aagaaaaaag accctaaggt ctcctttgct tttattatta aacgcgttca
    16921 actttacctg atttcaaagc acgagctgaa gcccaaactt ttttaggttt accatcgata
    16981 agaacagtaa ctttttgaag gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt
    17041 gaacggttgt ttcctgatac agtcttacga cctgtaaagt aacatacttt agccattgtg
    17101 ttttcctcct attagatcta atatagcgga tgtgctagca ccacataccg tactatgtta
    17161 tcacactttc ttgttttttg caagggaatt ggaagatttt ttatttgtgt cttaaatcag
    17221 gtcttgcgtg acattttctg ctctccacat gccattgttg attaacagaa caccagaatt
    17281 aaaattatgt gtataaaaat catctctaac tgcagctaag ggtatagccg tcaagtccaa
    17341 atcccacagc tcatctatcg attttcttac aacaatatct aaatccaaat acagtacacg
    17401 agactcgctt acatactttg gaataaaata cctaaaaaag ccgcatatga aagtccctca
    17461 aaggggagac gataaccttt cagaatacta ctgtcaatct aaacattcac aatctcacta
    17521 ttcaaagtct ctaatctttt ttccatcaat tggaaccatt ctcgcggaag gtcatcatta
    17581 aaaacataaa acttaagatt ataatgatga acacaaagag attttattgt tgtttcaact
    17641 ttatccatat aagcattatc tgcacctaag acaatcgctt ttttctcttc tttcactctt
    17701 tatcttattt ctttttattc ccatcatatg tttctacgta accattattt tcgcctattc
    17761 gttcgtaaaa ccataccagt ggagatttta gatgaagtcc cattacggtt tacaattttt
    17821 acattacgac acggagtttg gcaaatagaa tcgatttgcc aaacgtagtt agtgaggcag
    17881 ttagctagtt cgccaaatag cgactagcgt ccaacaattt ggaactttag ttccaattgt
    17941 tggtactgag tcacatcttc tcctctaact ctacgtctgg atacttgtcc gcaaaccagc
    18001 ggagggcaaa gtcattttca aagagaaaga ctggttggtc aaaacggtct ttggctaaga
    18061 tattgcgact tgacgacatc cgttcatcca agtcctcagg cttgatccaa cgaacggtct
    18121 ttttacccat tgggttcata actacttccg cattgtactc gccttccatg cggtgtttaa
    18181 agacttcaaa ctggagttga cctacagcgc ctagcatgta ctcacctgtt tggtaattct
    18241 tataaagctg aacggctcct tcttgcacca attgctcaat ccccttgtgg aaggattttt
    18301 gcttcataac attcttagca gaaactttca tgaaaatttc aggagtaaaa gttggcagtg
    18361 gttcaaattc aaacttgttt ttaccaactg tcaaggtatc cccaacttga taagtacctg
    18421 tatcgtaaac cccgataata tcacctgcca cggcattggt cacattctca cgactttccg
    18481 ccataaactg agtaacatta gacagtttag cccccttacc agtacgaggg agattaacac
    18541 tcatgccgcg ctcaaattcg ccagatacga tacggacaaa ggcaatacgg tcacggtgac
    18601 gagggtccat gttggcttgg attttaaaga caaagcctga gaaatccttg tcataaggat
    18661 ccacaatttc accgtctgtt ttcttgtgac catgtggttc tggagcaaac ttgaggaagg
    18721 tttcaaggaa ggtctgcaca ccaaagtttg tcagggctga accgaaaaag acaggcgtca
    18781 attctccagc cagaatagct tcctctgaaa actcattccc agcttcattt aaaagctcaa
    18841 tgtcatcctt gacttgatcg tagaaaggat tgctaccaaa aagtttgtct ccatcttcta
    18901 ggctagcaaa acgctcatcc cctttgtaaa gctctaaacg ttggttatag aggtcataca
    18961 agccctcaaa ggctttcccc atcccgatag gccagttcat agggtagcta gcaatgccca
    19021 agatttcttc caattcttgc aagagatcca aaggctcacg accgtcacga tccaacttgt
    19081 tcataaaggt aaagactgga atgccacgat gtttcacaac ctcaaacaat ttctttgttt
    19141 gagcctcgat ccccttggca gagtccacga ccatgaccgc agcatccacc gccatcaagg
    19201 tacgataggt atcttctgag aagtcctcgt gccctggcgt gtctaagata ttcacgcgct
    19261 tgccgtcgta gtcaaattgc ataacagatg aagtaacaga aatcccacgt tgcttctcga
    19321 tatccatcca gtcagattta gcaaaagtcc ctgttttctt cccttttacc gtaccagcct
    19381 cacgaatctc acccccaaag tagagtaact gctcagtgat ggttgttttc cccgcgtccg
    19441 ggtgggagat aatggcaaag gtacgacgtt tcttaatttc ttcttgaata ttcataagtt
    19501 ctctttcttt gattctctat ttttcttgtt tcaataactg agaatgattt ttacattgga
    19561 ttttaccatt cctttcaaca ctccattata tcggatttta gcattttttt caatttctat
    19621 ttcttttcac ttccccctcc cttatttata ggaaaatatg gtaaaataga acagactaaa
    19681 aatcatcatt tcacgaaagg atgcaagatg aaaattacgc aagaagaggt aacacacgtt
    19741 gccaatcttt caaaattaag attctctgaa gaagaaactg ctgcctttgc gaccaccttg
    19801 tctaagattg ttgacatggt tgaattgctg ggcgaagttg acacaactgg tgtcgcacct
    19861 actacgacta tggctgaccg caagactgta ctccgccctg atgtggccga agaaggaaca
    19921 aaccgtgatc gcttgtttaa aaacgtacct gaacaagaca actactatat caaggtgcca
    19981 gctatcctag acgatggagg agatgcctaa tgacttttaa caataaaact attgaagagt
    20041 tgcacaatct ccttgtctct aaggaaattt ctgcaacaga attgacccaa gcaacacttg
    20101 aaaatatcaa gtctcgtgag gaagccctca attcatttgt caccatcgct gaggagcaag
    20161 ctcttgttca agctaaagcc attgatgaag ctggaattga tgctgacaat gtcctttcag
    20221 gaattccact tgctgttaag gataacatct ctacagacgg tattctcaca actgctgcct
    20281 caaaaatgct ctacaactat gagccaatct ttgatgcgac agctgttgcc aatgcaaaaa
    20341 ccaagggcat gattgtcgtt ggaaagacca acatggacga atttgctatg ggtggttcag
    20401 gtgaaacttc acactacgga gcaactaaaa acgcttggga ccacagcaag gttcctggtg
    20461 ggtcatcaag tggttctgcc gcagctgtag cctcaggaca agttcgcttg tcacttggtt
    20521 ctgatactgg tggttccatc cgccaacctg ctgccttcaa cggaatcgtt ggtctcaaac
    20581 caacctacgg aacagtttca cgtttcggtc tcattgcctt tggtagctca ttagaccaga
    20641 ttggaccttt tgctcctact gttaaggaaa atgccctctt gctcaacgct attgccagcg
    20701 aagatgctaa agactctact tctgctcctg tccgcatcgc cgactttact tcaaaaatcg
    20761 gccaagacat taagggcatg aaaattgctt tgcctaagga atacctaggc gaaggaattg
    20821 atccagaggt taaggaaaca atcttaaacg cggccaaaca ctttgaaaaa ttgggtgcta
    20881 tcgtcgaaga agtcagcctt cctcactcta aatacggtgt tgccgtttat tacatcatcg
    20941 cttcatcaga agcttcatca aacttgcaac gttttgacgg tatccgttac ggctaccgcg
    21001 cagaagatgc gactaatctt gatgaaatct atgtaaacag ccgtagccaa ggttttggtg
    21061 aagaagtgaa gcgccgtatc atgctgggta ctttcagtct ttcatcaggt tactacgatg
    21121 cctactacaa gaaggctgga caggtccgta cacttatcat tcaagatttc gaaaaagtct
    21181 tcgcggatta cgatttgatt ttgggtccaa ctgctccaag tgttgcctat gacttggatt
    21241 ctctcaacca tgacccagtt gccatgtact tagccgacct attgaccata cctgtaaact
    21301 tggcaggact gcctggaatt tcgattcctg ctggattctc tcaaggtcta cctgtcggtc
    21361 tgcaattgat tggtcccaag cactctgagg aaaccattta ccaagttgct gctgcctttg
    21421 aagcaacaac aggctaccac aaacaacaac ccgtgatttt tggaggtgac aactaatgaa
    21481 ctttgaaaca gtcattggac ttgaagtcca cgtagagctc aacaccaatt caaaaatctt
    21541 ctcacctact tctgcccact tcggaaatga tcaaaatgcc aacactaacg tgattgactg
    21601 gtctttccca ggagttctgc cagttctcaa taaaggggtt gtcgatgccg gaatcaaggc
    21661 tgctcttgcc ctcaacatgg acatccacaa aaagatgcac tttgaccgca agaactactt
    21721 ctaccctgat aatcccaaag cctaccaaat ttctcagttt gatgagccaa tcggttataa
    21781 cggctggatt gaagtcgaac tagaagacgg tacgaccaag aaaatcggta tcgaacgtgc
    21841 ccacctagag gaagacgctg gtaaaaacac ccatggtaca gatggctact cttatgttga
    21901 cctcaaccgc caaggggttc ccttgattga gattgtatct gaggcagata tgcgttctcc
    21961 tgaagaagcc tatgcttatc tgacagccct caaggaagtt atccagtacg ctggcatttc
    22021 tgacgttaag atggaggaag gttcgatgcg tgtggatgcc aacatctccc ttcgtcctta
    22081 tggtcaagag aaattcggta ccaagactga attgaagaac ctcaactcct tctcaaacgt
    22141 tcgtaaaggt cttgaatacg aagtccaacg ccaggctgaa attcttcgct caggtggtca
    22201 aatccgccaa gaaacacgcc gttacgatga agcgaataaa gcaaccatcc tcatgcgtgt
    22261 caaggaaggg gctgctgact accgctactt cccagaacca gacctacccc tctttgaaat
    22321 ttctgacgag tggattgagg aaatgcggac tgagttgcca gagtttccaa aagaacgtcg
    22381 tgcgcgttat gtatctgacc ttggtttatc agactacgat gctagtcagt tgactgctaa
    22441 taaagtcact tctgacttct ttgaaaaagc tgttgcccta ggtggtgatg ccaaacaagt
    22501 ctctaactgg ctccaagggg aagtcgctca gttcttgaat gctgaaggta aaacactgga
    22561 acaaatcgaa ttgacaccag aaaacttggt tgaaatgatt gccatcatcg aagacggtac
    22621 tatttcatct aagattgcca agaaagtctt tgtccatcta gctaaaaatg gcggtggcgc
    22681 gcgtgaatac gtggaaaaag caggtatggt tcaaatttca gatccagcta tcttgatccc
    22741 aatcatccac caagtctttg ccgataacga agctgctgtt gccgacttca agtcaggcaa
    22801 acgtaacgcc gacaaggcct ttacaggatt ccttatgaag gcaaccaaag gccaagccaa
    22861 cccacaagtt gcccttaaac tacttgcaca ggaattggcg aagttgaaag aaaactagac
    22921 agaacaaaac cagccctaag gttggttttt tcttctctac caactcccaa taactatttt
    22981 ggctttattt ccagagtatt ttatggtaaa atgaagagta ataatatttg ttaaagaggt
    23041 aaaaacatga ttgaagcaag taaattaaaa gctggtatga cctttgaaac agctgacggc
    23101 aaattgattc gcgttttgga agctagtcac cacaaaccag gtaaaggaaa cacgatcatg
    23161 cgtatgaaat tgcgtgatgt ccgtactggt tctacatttg acacaagcta ccgtccagag
    23221 gaaaaatttg aacaagctat tatcgagact gtcccagctc aatacttgta caaaatggat
    23281 gacacagcat acttcatgaa tacagaaact tacgaccagt acgaaatccc tgtagtcaat
    23341 gttgaaaacg aattgcttta catccttgaa aactctgatg tgaaaatcca attctacgga
    23401 actgaagtga tcggtgtcac cgttcctact actgttgagt tgacagttgc tgaaactcaa
    23461 ccatctatca aaggtgctac tgttacaggt tctggtaaac cagcaacgat ggaaactgga
    23521 cttgtcgtaa acgttccaga cttcatcgaa gcaggacaaa aactcgttat caacactgca
    23581 gaaggaactt acgtttctcg tgcctaatct ctagaaagag gtcattctat gggaattgaa
    23641 gaacaacttg gcgaaatcgt tatcgcccca cgtgtacttg aaaaaatcat tgctatcgct
    23701 actgcaaagg tagagggtgt tcactctttt tcaaacagat cagtgtctga taccctttca
    23761 aaactttcac tcggccgtgg catttatctt aaaaacgtgg acgaagaact cacagcagat
    23821 atctatctct accttgagta cggagtaaaa gttcctaagg tagcggttgc tatccagaaa
    23881 gctgtcaaag atgccgtccg taatatggct gatgtagaac tcgctgctat caatattcac
    23941 gttgcaggta tcgtcccaga taaaacacca aaaccagaat tgaaagatct atttgacgag
    24001 gacttcctca atgactagtc cactattaga atctagacgc caactccgta aatgcgcttt
    24061 tcaagctctc atgagccttg agttcggtac gaatgtcgaa actgcttgtc gtttcgccta
    24121 tactcatgat cgtgaagata cggatgtaca acttccagcc tttttgatag acctcgtttc
    24181 tggtattcaa gctaaaaagg aagaactaga taagcaaatc actcagcatt taaaagtagg
    24241 ttggaccatt gaacgcttaa cgctcgtgga gagaaacctc cttcgcttgg gagtctttga
    24301 aatcacttca tttgacactc ctcagctggt tgctgttaat gaagctatcg agcttgcaaa
    24361 ggacttctcc gatcaaaaat ctgcccgttt tatcaatgga ctgctcagcc agtttgtaac
    24421 agaagaacaa taaaaagaaa aagtgtttga tagatatcaa acactttttc tttgcctccc
    24481 actatctaaa aaaatgataa tagatataat tgtaaacaaa aatccagata ggttttgcat
    24541 gattgagaaa gttaaaaaaa ctatggcaga gaatcgttaa tctcagattg tcggtagaac
    24601 gataaacaag ggcaaaaaag aaaccaatca gactataata taataaacta attggatctc
    24661 tgtgagatag tatcaaatgg ctaatcccaa agataaggcc tgataagatg acatctaaat
    24721 agtactttga cttaggaaag aaggtattca taaaataccc tctatcaaga gtctcctcaa
    24781 aaacaggacc gatgattaca agcaggacaa aagataagat agtcgataaa aaggttggtt
    24841 gtccatttga aagaaccacg gtaaaatact catcatgaat attcctatgg ttaatcaaat
    24901 gagcatagcg tgcctaaaaa ttaccgagaa tctgataaac cacataagtt gcaaataagt
    24961 agaagacaaa tgaccagttc cagctctttt tttcaaagat aaagagcatc tttttctttt
    25021 ttaacctcca aattaataga aggaaacttc ccactaatac cattgttaaa ataagagaat
    25081 agacatcagc tcctaaccct aaaatgatcg tcacatacaa tccaattgtt tgtggtaaat
    25141 aggtagatag taaaataata agcaaaaata ttccaaattg tcttagtttt tttgtgtttc
    25201 tcatcgtact tttttgaaag attaccctgc tcggaagccg tacttccaag catctatata
    25261 agaattaagt gccccttgcc tcatataggg agcaaattct ctataatata accatctact
    25321 atatccatct tcccaaacag caagaccacc tgaagtttgc tccaagtcct cagttgaaag
    25381 aattgtaaat gtatttgtac ctgtcattgc aagtaccttc ttaaaatata gtgatttgaa
    25441 ataagatgta aacaactcta tcaggaaagt caaattaatt tatagaaata ttttagcagt
    25501 caaggtgtac tgtta
//
LOCUS       DAVDFK010000026        23021 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.26, whole genome shotgun sequence.
ACCESSION   DAVDFK010000026 DAVDFK010000000
VERSION     DAVDFK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.26"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..681
                     /locus_tag="VUR04_001383"
     CDS             <1..681
                     /locus_tag="VUR04_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET5341269.1"
                     /translation="IPFVASLVSSLIMIYIIGAPIAAFTNWLTSLLQSLGSASNGLMG
                     AVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQLVNIATPVGFGLAYFIAKL
                     LKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVPGLIATGIGGAVGGAVSLTM
                     GADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYAILRKPIKHTEPVMTVEEEI
                     DLSDIEIL"
     gene            692..1387
                     /locus_tag="VUR04_001384"
     CDS             692..1387
                     /locus_tag="VUR04_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET5341270.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKATIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            1424..3394
                     /gene="tkt"
                     /locus_tag="VUR04_001385"
                     /pseudo
     CDS             1424..3394
                     /gene="tkt"
                     /locus_tag="VUR04_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
     gene            complement(4112..7204)
                     /locus_tag="VUR04_001386"
                     /pseudo
     CDS             complement(4112..7204)
                     /locus_tag="VUR04_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828348.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
     gene            complement(7439..8677)
                     /locus_tag="VUR04_001387"
     CDS             complement(7439..8677)
                     /locus_tag="VUR04_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341271.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYTFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLIMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIGFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            complement(8679..11179)
                     /locus_tag="VUR04_001388"
                     /pseudo
     CDS             complement(8679..11179)
                     /locus_tag="VUR04_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397625.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            11728..12405
                     /locus_tag="VUR04_001389"
     CDS             11728..12405
                     /locus_tag="VUR04_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET5341272.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEESGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            12392..13189
                     /locus_tag="VUR04_001390"
     CDS             12392..13189
                     /locus_tag="VUR04_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET5341273.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQFFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            13206..14309
                     /locus_tag="VUR04_001391"
     CDS             13206..14309
                     /locus_tag="VUR04_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET5341274.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            14565..15584
                     /gene="galE"
                     /locus_tag="VUR04_001392"
     CDS             14565..15584
                     /gene="galE"
                     /locus_tag="VUR04_001392"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET5341275.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            15586..16551
                     /locus_tag="VUR04_001393"
     CDS             15586..16551
                     /locus_tag="VUR04_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5341276.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(16602..16808)
                     /locus_tag="VUR04_001394"
     CDS             complement(16602..16808)
                     /locus_tag="VUR04_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET5341277.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            16860..17336
                     /locus_tag="VUR04_001395"
     CDS             16860..17336
                     /locus_tag="VUR04_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET5341278.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            17345..18016
                     /locus_tag="VUR04_001396"
     CDS             17345..18016
                     /locus_tag="VUR04_001396"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET5341279.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            18147..18485
                     /locus_tag="VUR04_001397"
     CDS             18147..18485
                     /locus_tag="VUR04_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET5341280.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            18488..19117
                     /locus_tag="VUR04_001398"
     CDS             18488..19117
                     /locus_tag="VUR04_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET5341281.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            19357..20508
                     /locus_tag="VUR04_001399"
     CDS             19357..20508
                     /locus_tag="VUR04_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5341282.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLFQKRA"
     gene            20826..21575
                     /gene="truA"
                     /locus_tag="VUR04_001400"
     CDS             20826..21575
                     /gene="truA"
                     /locus_tag="VUR04_001400"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET5341283.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            21565..22338
                     /locus_tag="VUR04_001401"
     CDS             21565..22338
                     /locus_tag="VUR04_001401"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET5341284.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNDLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            22316..22777
                     /locus_tag="VUR04_001402"
     CDS             22316..22777
                     /locus_tag="VUR04_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5341285.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         6716 a         4229 c         4869 g         7207 t
ORIGIN      
        1 attccttttg tagcctcttt ggtaagtagt ttgattatga tttatattat tggagcgcct
       61 atcgcagcct ttaccaactg gttgacgagc ttattacaaa gcttgggaag tgcttcaaat
      121 ggtttgatgg gggcagttat tggagttctc agtgctgttg actttggtgg cccacttaat
      181 aaaacagtct atgcgtttgt gttgacttta caggctgaag gtgtgaaaga accattgact
      241 gctttgcaat tggtgaatat tgctacacca gttggatttg gattggccta ttttatcgcg
      301 aaattactca aaaaaaatat ctatactcaa gaggaaatcg aaacattgaa atcggctgtt
      361 cctatgggga ttgtcaatat tgttgaaggt gtaattccga ttgttatgaa taacttggtt
      421 ccaggtctca ttgcaacagg tatcggtggt gctgttggtg gtgctgtttc tttgacaatg
      481 ggtgctgatt ctgccgtgcc atttggtgga gtgcttatgt taccaaccat gactcgtcca
      541 gtagctggta tttgtgcttt gttagccaac attgtagtca caggacttgt ctacgcgatt
      601 ttgagaaaac caataaaaca tacagaacca gttatgactg ttgaagaaga gattgatttg
      661 tcagatattg aaattttgta agagggtaac gatgtcaaga attgaatttt caccatcttt
      721 gatgaccatg gatttggaca aattcaaaga gcagattact tttttgaatg ataaagtagc
      781 atcttatcat atcgatatta tggatggcca ttttgttccc aatattacct tgtctccttg
      841 gttcattcaa gaagttcaaa aaattagtga cacaccttta tcagttcatc tgatggtcac
      901 agacccaacc ttttgggtag atcaagttct cgatttacaa tgtgagtata tttgtattca
      961 tgctgaagtt ctgaatggtc ttgcttttcg tttgattgat aaaattcatg atgcaggtct
     1021 aaaggctggt gttgtcctta atcctgaaac acctgtttct acaatctttc cctacattga
     1081 tttacttgac aaagcaacta ttatgactgt agatccaggt tttgcaggac aacgcttttt
     1141 ggagtctacc ttgtataaaa tccaagaact ccgtcagctt agagttcaga atggttatca
     1201 ctacatcatt gagatggatg gttcttcgag tcgtaagact ttcaaacaaa ttgatgtggc
     1261 aggaccagat atttatgtta taggtcgcag tggattattt ggtttggatg acgatattgc
     1321 caaagcctgg gatatctgtt ctagagatta cgaagaaatg accggaaaaa caatgccaat
     1381 caaataatgg tttgagaaga aatttattag ttaggaggaa tatatgtcac tacaatcagt
     1441 taacgccatt cgttttcttg gcgtagatgc tattaacaaa tctaattctg gtcacccggg
     1501 aatcgtcatg ggtgctgcgc caatggctta tagcctattt acaaagcacc ttagaattac
     1561 acctgagcag ccaaactgga ttaaccgaga tcgctttatc ttgtctgcgg gtcatggatc
     1621 aatgctactg tatgctctct tgcatttaac agggtatagc gatgtatcca tggacgagat
     1681 taaaaatttc cggcaatggg gatctaagac acctggtcat cctgaagtga cgcatacgtc
     1741 tggtgtggat gcgacatctg gtccgcttgg tcaggggatt tctactgccg ttgatttcgc
     1801 ccaagcagag cgttttttag ctgctaagta caacaaagat ggtttcccta tttttgacca
     1861 ttatacttat gttatcgctg gagacggtga cttcatggaa ggagtgtctg cggaggcggc
     1921 ttcttatgca ggtcatcaag ctttagataa gcttatcgtc ctctacgact ccaacgacat
     1981 ctgcttggat ggtgagacca aagatacttt ctctgaaaat gttcgcgccc gttacgatgc
     2041 ttatggttgg catacagttc tggtagaaga tggaacagat ttagcagcaa tttctacagc
     2101 aattgagacg gccaagtttt ctggtaagcc gagtttgatt gaagtgaaaa cggtaattgg
     2161 ttaaggctca cccaataaaa gtggtacaaa tgctgttcat ggtgcaccac taggagcaga
     2221 agaaacagga gcaactcgta agtttttggg atgggattac gatccatttg aagtaccaga
     2281 ggaagtatat tctgatttca agacaaatgt agcggatcgt ggtcaggagg catacgatgc
     2341 ttgggctagt ttggtgtctg attacaaggt tgcttatccc gaagttgcta gtgagattga
     2401 cgctattgta gctggaaaat cccctgtaac cattactgaa aaagacttcc ctgtctatga
     2461 gaatggcttc tctcaagcaa ctcgtaattc gtcccaagat gctattaata cagcagcagc
     2521 agttttacca accttcttag gtggatcggc agacttagct cactccaaca tgacctacat
     2581 caaggcagat ggcttacaag ataaatataa tccattaaac cgcaatattc agtttggggt
     2641 acgtgaattt gccatgggaa caatcctcaa tggaatggct cttcatggtg gtttacgagt
     2701 ttatggcgga accttctttg ttttctttga ctacgtcaaa gctgctattc ggctatcagc
     2761 cattcaggag ttgcctgtaa cttatgtctt tacccatgat tcaattgccg ttggtgaaga
     2821 tggtccaact catgaaccag ttgaacattt ggcaggttta cgctcaatgc caaacttgac
     2881 tgttatccgt ccagcggatg cccgtgaaac tcaagcggct tggcatcatg ccttgaccag
     2941 taccaccact ccaactgtca ttgtcttaac ccgtcaaaac ttggtagttg aagaagggac
     3001 agactttggt aaggtcgcta aaggagccta cgtcgtgtat gatacctcgg gatttgatac
     3061 tattatcatt gctacaggat ctgaggtcaa tctagctatc aaagctgcta aggaattggt
     3121 tttacaaggt ggtaaagtac gtgtggtatc tatgccctca accgaactat ttgatgctca
     3181 agatgctacc tacaaggaag acattttacc atctaagact cgtcgtcgtg tggccattga
     3241 aatggcagcg acccaaagtt ggtacaagta tgttggtttg gatggcgcgg tcatcggtat
     3301 tgacatcttc ggtgcgtctg ccccagctca gactgtgatt gataattatg gatttacggt
     3361 agagaatatc gttgctcaag ttaagtccct atagaaacca attacaatga agatacagct
     3421 gttgtcagac tagcagatgt agtgatagac actaatcaga tgattggtta tttaaaaact
     3481 ataatgagaa tgtaataatt tatctacgaa agttatagta gatagtatac acaatagagt
     3541 ataccctgaa acggttgcga agtacgctaa tcactttgct actgatctag atagtttctt
     3601 taatcaataa acacagcatc cacagattga cttaggatat tgtaagtttt ttgaaagcta
     3661 gagagaaggt ctctaaaatt aaaaaacgca tagtatagga tgttgaaatg aacagccttg
     3721 atattatgcg ttttattgtt ggaatattta ctttattttc tcctgaaatt gagtttttcc
     3781 ttagctccta tttttaggta cgacgagtct atcgtagatt tggtgtgcaa ggcctacgtg
     3841 tctattatct atcggtgaac ctaagagcga ctctcaagcc tgcttgtatt gaggtagaag
     3901 aatcaaatgt ctgtggctag actatttgaa gtatgacgca agaaataata ctcttcgaaa
     3961 atctcttcaa accaggtccg ttctatctgc aatctcaaag cagtgctttg agcaacctgt
     4021 gtctagcttc ctagtttgct ctttgatttt cattgagtat aaaaagaact agatagaccc
     4081 actaagtgtg gttactctag ttctttttcg tttattcaac acccaagatt tctttaatat
     4141 tatcaacgct cagattgctt ctgctttctt gtccttcaag gacggtgttg aagagttctt
     4201 ttttactttc ttggagttct tggatttttt cctctatggt tccaagggtg atgaggcgat
     4261 agacatcgac ttgtttggtc tggccaaggc ggtggcttcg accgatagct tgcatctcga
     4321 ctgctggatt ccaccagagg tcacagagga tgacggtatc agctcctgtt agattcagtc
     4381 ctgttccacc tgcttttagg gaaatgagga agcagtcttt ttccccttga ttgaaaagat
     4441 tgaccatttt ttgacgttta tctgaaggtg tttgtcctgt tattttaaag tgagacattt
     4501 cttttttctc tagttcttgc tcaatgagat caagcataga tgtgaattgt gaaaagataa
     4561 gtggtcgtga ccctttttca cgaatggtgt ctaggagctc gaataagctg tccatttttc
     4621 cactatcccc tttgtagtct tctaaaaaga gagcaggggt attacagatt tgtctaagtc
     4681 gggttagtcc tgctaagatt tcaattttat gacgtttaat ctcataggcg ctggctcctg
     4741 aaaccatttc ttgcatgcgt cgaagttgag ctagatagag cgttttttgt gaactgctga
     4801 gttcattgct gtagaggtga tcgctcagtt caggtaattc tgtcagaact tcgtcttttt
     4861 tcctacgcag gacaaaaggt taaatcagtt tagcaacgag ttgaggtgac aattttgaaa
     4921 attccttttt acttggtagg agacctggta atactatctg gaaaatagac caaatctctt
     4981 cgagacggtt ttcaatagga gttccagata gggcatagca ggttttgaca tcaaattctc
     5041 ttaaagcttg tgctgttttg gtctgactat tttttatcat ctgtgcttca tctaggatga
     5101 ggtagtcgta agactgcttt tgataatgtt caaggtcaga tcgaaaagat ggatagcttg
     5161 taatagtgat agtagcagat ttttcaattt gtttgatacg ctcagttttg ctaccatagg
     5221 ctacttcaac ctgtttgtga ggtacaaatt ttcggaattc ttccttccaa ttgtaaagaa
     5281 ggctggctgg agctaggata agagctttct gaactggttt aaggttggct tccagaagag
     5341 tgatggtttg caaggttttc cctagcccca tgtcgtccgc caggattcct ccaaaatgat
     5401 aatgatccag catactcagc cacttgactc cttctttttg ataggagcgg agtttggtct
     5461 tgacttcata aggcttgata tcaaattctt cagggtgggt caggtcataa gccatttttt
     5521 tgaaatcacg agaaaaattg acatgttcat tgtctttgaa ggtttcagaa agactaaagg
     5581 cacgagattt gtgcatcttg atttttccgt ctgaaaattt agcgcgaaga tcttggaggc
     5641 tttgggcaac cttgagactt tcatcgtcaa agactagaac ctttccttgc ttggtttggt
     5701 agtggttttc ttgattccat aaagcttgga tagccttttc aacctcatct tctgaaatca
     5761 tagaaaaatc aaactgaact gaaaggaagc cttcgtcgtc aaaaatgtca atgacagcag
     5821 gatcttctac taagagtttt tcaagcgatt catctagttg aacttgaccc agagtacgaa
     5881 aactgggtag ttcttttagg aagaaatcaa cgattttgat tttggaaaga ctatgaaatt
     5941 cctctttgaa accagcagaa agcagttgat gatagatttt tctagctttg ctagcttggt
     6001 aagtataggg gagggttagg agatcttgtt tagaatggac ttgattttct ccaaaggacc
     6061 acaccatgtt gagggcaatt tcatttctag tcttggagaa ggcaaaggtg gggataaagt
     6121 catggatttg taattcatct ggaagactga taggaacata gtttgagatg atattacaga
     6181 tttgcatgag ttcagcctta ttttcctgtg aaaagataag aggagaactt tcttgataat
     6241 gatagatcca agtagctaat ttatccaaaa agtaacggtg ttcttctttg atgatgtgga
     6301 agtgattgtg tcgaatccaa agtttttctt gaataatgaa accaaaacaa gctgtattga
     6361 tgatttcata atggttatta gatttgacaa ctttaaaaat ttcctcttcc gggataaagg
     6421 gactatcatc taagaatata agagggtatt cggcttttga ggttacatat tggaagacat
     6481 ccaaagcttg aaaaagtggg acgaggtcgt ttaaatagct aacaggagtc tctaaatagc
     6541 gtccgcaatc tctagggcta atgccataac tgaagttgaa ataagaatgt tcatttctat
     6601 cgataaaata ttttttgata tagaggagta ggttttggga tgcttgatta aactgattca
     6661 aggataatct gattgtcccg attttctgtg aaacaaagta attttcctct tggaaaatga
     6721 gaaaaatgaa gtgagctata tccttgataa cataggcacg agaagcctgt tctacctgta
     6781 gttttagggt ccaagctagg ctatgatttc ggatttcgac ttgtccatga agggaaagtg
     6841 aaggcgccac cgctttttct tctaccagtt cgtcttggag ttcatcagat ggcaaggtag
     6901 gaatcagttg gctggcaaaa cttggtttat gactcgcttt accaatgcgt tcttgaatag
     6961 cttgggggag actacgaaaa taaagatcca tggcaaccca gtgtttacag actccctgat
     7021 tttggaaatc cttacaatcg caatgaaagc cagtcaaatc gaagtgctcc atactggtca
     7081 ggatgttggg ctccagatgc atggaaatac catcataggt attggggtgc ttaaaatatt
     7141 ccttattttc agtatcaaaa tagtttttta tctgttggaa aatagagcgg ccatccattc
     7201 tcatacgagc aggtagtctt ctatcgggaa ctaacctctg ttctaatcat tcttttctct
     7261 atcttatcag attttatagg aaaagaatag atttatctta cataaattgc atcttgatag
     7321 ggattggaaa catttgtagt tgcaagatag ttgtatgtaa tatcgataat caattacaag
     7381 gagattacga ttccatagaa actatcaagt gaaaactgac ttatccataa cattctagct
     7441 aaacttcttc ttggtttggt aagtttttca tctggtgaac tagataggct gctataagta
     7501 gtaaaattat aagagcaaaa gcaacaactt ccagaccagc acttgttgca agaaatacga
     7561 gagcaaggga taggacagct gggataagta agttgataac attgatggat gattgaactg
     7621 atcccattaa ctcctcagga atgattccaa aaatcatggc ttgcaagcga ggactcaata
     7681 ctcctgccga gaaagcatca cctgcacttc ctagtaaaat aagtaaaaaa cttccacgta
     7741 gaaaacctat aacaatgaga gactccatca atagactcca ataaatattc agacgaatag
     7801 aaattttttt agatagaaat ccactcagaa gtccacctaa aataacatga agaaggctta
     7861 tcattatcaa aattgccaga ctttgccctg ttgacaaacc cataaaagga tggtgaatca
     7921 gtagaatcgc actgacaggc tctaccatta tcaaaacagc ttgactaatg gacaaaatcc
     7981 aaagcaagac catgacatct tccatagtca tcaataattt cattgactct ttcaaatgct
     8041 ggaaaaagct actcattcct acataaggag gaacttcgat tttttcttcc tcttttttca
     8101 agcggtttcg aataagtaga cttcctagaa aggcaaataa aaaggttaaa acatttacaa
     8161 aagctagagt agaaatgcta aacagtccta aaaagactcc tccgctgaga ttacctatca
     8221 aacgtacaat ggaactcgtg gactgcctaa aacccatagc ctccgtcata tcatcgttta
     8281 ttagtcgtat gtaaatcggt gtcagcatgt atcctgcaag aaaaccaatc gtatctgaaa
     8341 tcaagttcat gctgcaaata aagaaaacag aaaagagaga gaagtcggta cttgtcagga
     8401 gcaaagtcac tccagaataa aggaggactt tgataaagag gatagaaata tacttgctaa
     8461 ttcgattttt ttgaaaatca gctataactc cagtaaaaag ttgcaagacc tgtggaatag
     8521 tttctgacag actgatcaaa aatatagcta agggagcaaa cgtataagaa gagacataat
     8581 tgataaaagc taagtaaaaa atagtgtctc caaaacttga aatccactca ttcactgtta
     8641 gctgacgaaa agctcgattt ttaagaaaaa tatgcatatt aatctccttt acttaattca
     8701 aatgggaatg tataaccgag taaagtccaa taaataccca gatttcccac accaaagtca
     8761 aaataactgt ttattccatc ttccccttga aattgtaata atctatcatc attacgataa
     8821 gaacgagtca ataagattct ttttatcaat tgttcaacct tttgattttt attgtatatt
     8881 gttgtttgca ataaactact taagccatgg caaaaactag ttcccattgc ttcatattgt
     8941 tgcaccattt caagttgtga tttatagatt atctcagaat atctttcttt atcaatcaaa
     9001 cacagataca atattaatcc tgaaacgcct tcacaccaag aaagacctaa atgatctaat
     9061 ttagaaaagc ttgaaagtct ttcttctagt aattcagata tcccatcgga aaatttttgt
     9121 aaatgatttt gatagcgact acctccaaaa atatcagcat aggcttttaa tacataggca
     9181 gcacctgaac gcccgtgagc aaaattatta aaatatatat ctccattatc ctcggactct
     9241 aataaactgt atgcatcatt tatattgttc ttaataaaat ttgctagttt tttatcatca
     9301 acaatggtac aatatttcat caaacagagt aggataccag accttcctaa agcaaaatct
     9361 aagttactaa tattgtcata aacccgcatt aaatgatcga ctaatctctt acttatgtct
     9421 attaaatatc tctcctttgt tttttcatac ctatctagga ttccaaatag gaaacctgct
     9481 ttcccaaata gtagagagta accatgtaaa aaattagttg cttcataatt ttctaatttc
     9541 gtaagccatt ctttaacggt attttcatct tcctcaacat aatatttatt cataaaaaat
     9601 aaaactcctc caaaaccatg ttggaaagaa acaggactta cgaactcacc aaattcattt
     9661 gacggaaaca aacgaccaga tttgtccata gatttagcca gtaagtatga ttttatattc
     9721 tcagcctcct ctttaaaatt atatttttca aaataacttg aaaaatctgg agtatttaaa
     9781 agaatgtcac ttggaatttg tttcaattgc tttatttttt ggattttttc tccatggctc
     9841 atcattaata aatcgtatag ccagtattct tgttgtttag ttattttatt gtctaatcta
     9901 gctattttta tcagatgaca tatttttata aaggccgata atcctgtttt ttgatcacct
     9961 tttgaaaagg ataaaaaatc acctgttaat aaagaaaatc caattagtgc taaactaaaa
    10021 taatcttgtt gaactgagct gatagttagg tcagtatctg gattaaccat cattggtgtt
    10081 ttaactcgtc ttaccttatc cttgatagga gtcattgtct ccaagtctat taatgttata
    10141 tcaccttttt tggtgtatat aaaatttgta ggagctatat ctacaatttt atatcccagt
    10201 ttatggatgt catttactat attcacaatg ttgtccagtg atttttctct aatatttaag
    10261 gagtattctg tttctcgaat aaattcttca aagtttaacc cgtcaacttg ttcctgaaca
    10321 agaaaataat catccactat ataaaattca tcaattaaat tagtagtata acttttatcg
    10381 gctaactttt ttagcatgta agcctcattt tttatatcat caagtgctgt ccattctcct
    10441 tcggcatcat aattcacaaa aggtcttgac tgcttgatga ttattttttg cccgtccgat
    10501 tttctaattg cccgataaac atttccttta tttgatctct taataatttt ttctattttg
    10561 tatttattta ttgcagagtc cttacttgaa acttcacatg tggtttgaaa ataaatcctc
    10621 ttttcttctt ctgaaaataa atccattttc cagctaggaa gactagggaa attttgtctc
    10681 ttatcttcta catagttctt ccttttttca tctagcaata aatagatgac ctttttattt
    10741 ttttcatcat aagcctgttt tttaaaaaaa gcaccatatc tataatgaac tagagaatgt
    10801 agtccacatt gaaaatcaga tagtattttt ggagccttaa attctgacag tttattcgta
    10861 agattacaaa tcatactctt ggcttcagat tctgacttag gatatagagt tataaatttg
    10921 ttagcagtag ggctcatttc cctaggggaa ttaatttttt taattcctct aaatttttaa
    10981 cgactttaaa gctacaatta tttagtttgg atagtttata cacaatctta aaaatatcta
    11041 cagcatcttt gatttgagaa cttatgtgta ttttccagcc ttgtgtaggc atcttatctg
    11101 acaaatgata gtaatttcaa atatcatctt gttggaaatt tttatcacat tttaaacatt
    11161 ctttctctaa taaatccata acaaactcct aattattaaa ataggctaga gacacagcac
    11221 tagcctattc cgtaagtaaa gctacttatt ttacataaaa tataactagc aacctgtaat
    11281 taaacaagta aaagaacaat acttagggag acctgtgaca atgacatctt cctctggaag
    11341 tagttctaat tcaaacaatg tttgttccat gactgtatct tcctgttatg ataaattcca
    11401 gaaagcatag agcaaattcg tggttcgtct gactaaattt cttatctgaa caccaccttc
    11461 aaatacaaat tttagtcaaa cttttatttt ttctaacttt ctaattatat tctaccgtgt
    11521 gtttttatat gtcaagaatc ttctgaataa actgtttatt ttttattttt tgatattttt
    11581 gcaaattgtt taaaatcttt caattggatt cacttattac tttaggacat tgaaacttct
    11641 ttcgccagag gtgcttatat tactgggaag ttgaagattg aaatgtggta taataagagg
    11701 taatagagtt ttggaaagtg agagaagatg atttcaaaga gattagaatt ggtagcttcc
    11761 tttgtgtcac agggggctat tttactagat gtgggaagtg accatgctta tctgcctatc
    11821 gagttggttg agagaggcca aatcaaaagc gctattgcag gtgaggtggt ggaaggtccc
    11881 tatcagtctg cggttaaaaa tgttgaggct cacggcctaa aggagaaaat ccaagtccgt
    11941 ttagccaatg gcttggcagc ttttgaagag actgaccaag tgtctgtcat taccattgct
    12001 ggcatgggtg gtcgtttgat tgctaggatt ttagaagaag gtttggggaa gttagctaat
    12061 gtagagcgtt tgatcctcca gcccaataat cgtgaagacg acttgcgtat ctggctacag
    12121 gatcatggat tccagattgt agcagaaagc atcttagaag aatctggaaa gttttatgag
    12181 attttggtgg tggaagcagg acaaatgaag ctatcagcca gtgatgttcg ctttggtccc
    12241 ttcttgtcca aagaagtcag tccagtattt gtccaaaaat ggcaaaaaga agctgagaag
    12301 ctagagttcg ctctcggaca aatcccagaa aaaaatctgg aagaacgtca agttctagta
    12361 gataagattc aagctatcaa ggaggtgctc catgttagca agtgaagtga ttcaagctta
    12421 tgaagccttt tgccctcagg aattttctat ggagggagac agccgtggtc tgcaaattgg
    12481 cactttagac aagggtatcc aaagggtcat ggttgccctc gatattcgtg aagagacggt
    12541 ggcagaggcc attgaaaagg gtgtggactt gattatcgtc aagcacgcgc ctatctttcg
    12601 tcctatcaag gacttgcttg ccagccgtcc gcaaaatcag atttacatcg acctgattaa
    12661 gcatgacatc gcagtttatg tcagccatac caatattgat atcgttgaaa atgggctcaa
    12721 tgactggttt tgtcagatgc taggaatcga ggagacgact tatctgcagg aaacaggtcc
    12781 agaacgtgga attggacgta ttgggaatat tcagcctcag acattttggg aattggccca
    12841 acaggtcaag caagtctttg acctagatag ccttcgaatg gtgcattatc aagagaatga
    12901 tttgcagaag cctatttcaa gagtagcaat ttgtggtgga agtgggcagt ttttctataa
    12961 ggatgctttg gcaaaggggg cagatgtcta tatcactggt gatatctact accatactgc
    13021 tcaggatatg ctgtctgatg gcttgttagc attggatcca ggtcactata tcgaagtgct
    13081 ttttgtggaa aaaatcgcag cactccttac tcaatggaaa gagaaaaaag gctgggaact
    13141 agagatttta cctagtcaag catcgaccaa tcctttccgt catatctagt tagaaagtga
    13201 agacaatgaa aaaagttgcc attattggag caggaattgt gggagcaaca gctgcctact
    13261 acctctcgag agaaagtgac ctagaggtga ccgtttttga ccatgagcaa ggtcaagcca
    13321 ccaaggccgc agcaggaatt atcagtcctt ggttttccaa acgccgtaat aaagcctggt
    13381 acaagatggc gcgcttgggg gctgattttt atgtggattt attagctgat ttagagaaat
    13441 caggacaaga aatcgacttt taccagcgtt cgggagtctt tcttttgaaa aaggatgaat
    13501 ccaagttgga agaactttat caactggccc tccagcgcag agaagaatct cccttgatag
    13561 ggcaattagc cattctggac caagcttcag ctaatgaatt attccctggt ttgcagggat
    13621 ttgaccgcct gctctatgct tctggtggag cgagagtaga tggccaactc ttggtaactc
    13681 gtttgctaga agccagtcat gtcaagctgg tcaaagaaaa agtgactctg acaccgttag
    13741 catcaggcta ccagattggc gaagaggtgt ttgatcaggt tattttggca acgggagctt
    13801 ggttggggga catgttagag cctttaggtt atgaagtgga tgtccgtcct caaaaaggac
    13861 aactacgaga ttatcagctt gcccaagaca tggaagatta ccctgttgtc atgccagaag
    13921 gggagtggga tttgattccc tttgcaggtg ggaaattatc cttgggcgct acccatgaaa
    13981 atgacatggg atttgatttg acggtagatg aacccttgct ccaacaaatg gaggaggcca
    14041 ccttgactca ctatctgatt ttggctgaag ctacttcaaa atctgagcgt gttggaatcc
    14101 gtgcctacac cagtgatttc tctcctttct ttgggcaggt gcctgactta actggtgtct
    14161 atgcagccag tggactaggt tcatcaggcc tcacaactgg tcctatcatt ggttaccatc
    14221 tagcccaact gatccaagac aaggagttga ccttggaccc tgaaaactac ccaattgaaa
    14281 actatgtcaa acgagtaaaa agcgaataat actcaatgaa aatcaaagaa caaactaggc
    14341 aactagccgc gggttactca aagcactgct ttgaggttgt ggatagaact gacgaagtca
    14401 gtaaccatac ccatggcaag gcgacgttga cgtggtttga attggatttt cgaagagtat
    14461 aagcatttta ctgaaatttt atcaggtagt ttaggatggc aaatgacatt ccctgtcaaa
    14521 aatggtaaaa taagaaaaaa taatctgaga atcgaggaaa aaagatgcaa gaaaagattt
    14581 tggtaactgg tggtgccggt tttattggaa cccacactgt tattgaattg atccaagcag
    14641 gtcatcaagt tgttgtggtg gataatcttg tcaatagcaa tcgtaagagt ttagaagttg
    14701 ttgaaagaat cacaggagtt gagattcctt tctatgaggc agatattcgt gacacagata
    14761 ccctcagaga tattttcaag caggaagaac cgactggtgt cattcacttt gctggtttga
    14821 aggctgttgg cgaatcaaca cgtatccctc ttgcctacta tgacaacaat atcgctggaa
    14881 ctgtcagcct tttgaaagcc atggaagaaa acaactgtaa aaacatcatc ttcagttctt
    14941 ctgcgacagt ttacggggat ccgcacacag tgcccatctt ggaagatttc ccactttcag
    15001 tgaccaaccc atacggtcgt actaagctca tgctagagga aattttgact gatatttaca
    15061 aagcagactc agaatggaat gttgtcttgc ttcgttactt taacccaatc ggagcccatg
    15121 agagtggtga tttgggagaa aatccaaacg gtattccaaa caatctcttg ccatatgtga
    15181 ctcaagtagc cgttggaaaa ttagagcaag tgcaagtgtt tggagacgat tacgatacgg
    15241 aagatggaac aggtgttcgt gactatatcc acgttgtcga tttggctaag ggtcacgttg
    15301 cagctttgaa aaaaatccaa aaaggttcag gactaaacgt ttataacctt ggaactggta
    15361 aaggttactc agttcttgaa attatccaaa acatggaaaa agcggtggga cgtcctattc
    15421 cttaccgcat cgtagaacgt cgcccaggtg atatcgctgc ctgctactca gacccagcaa
    15481 aagctaaagc agaactcggt tgggaagcag aactcgacat cacccaaatg tgtgaagacg
    15541 catggcgttg gcagagcaag catccaaatg gatttgaaga ctaagatgat gatttcaatc
    15601 atcgtccctt gtttaaacga agaggaagta cttcctcttt tttatcaggc tctggaagct
    15661 ttacttccag atttggaaac agaaatcgag tatgtctttg tcgatgatgg atcaagtgat
    15721 gggaccttgg aactcttaaa ggcctatcgg gagcaaaatc cggcagtcca ttatatttct
    15781 ttctctcgaa attttggcaa agaagcagcc ctttatgcag gcttgcaata tgcgacagga
    15841 gatttggtgg tggtgatgga tgcagacctc caagatcctc ctagtatgtt gtttgagatg
    15901 aaaaatgtac tagacaaaaa tgtagacttg gactgcgttg ggacacggag aactagtcgg
    15961 gagggagaac ccttctttcg cagtttctgt gctgttctct tttatcgcct catgcaaaaa
    16021 atcagcccag tagctctgcc gtcgggtgtc cgtgattttc gtatgatgag aaggtctgtg
    16081 gtcgatgcca ttttaagttt gactgagtcc aatcgttttt ctaagggact ctttgcctgg
    16141 gtcggcttta aaacccacta tctggactat ccaaatgtcg aaaggcaggc tggcaagacc
    16201 agttggagtt ttaggcaact ctttttctac tccattgaag ggattattaa tttttcagat
    16261 tttcccttga ttatagcctt tgtagctggt ctcctatctt gttttctttc tctgctgatg
    16321 accttttttg ttgtggttcg aaccctcatt ttgggcaatc cgacatcggg ttggacctct
    16381 ctgatggctg tcattctctt tcttggaggc attcaactct tgaccattgg gattctcggc
    16441 aagtatatca gtaagattta tttagagact aaaaaaagac cactttatct tatcaaagaa
    16501 aaaagtgacc ttcctgattt tacagaaaaa aataaagtga aaagactata attttacatg
    16561 gaaatgtgct aaactagagg gagtggatta tcgccattga tttaggcttc ctggtttcca
    16621 atcagggcgc gagttgggca atttttaaca gcctctaaga catcctgact aggagaaatt
    16681 tctttttcca gttggtcagg gtcatcgtaa aaacgcacga ttccattatc gtggtaatca
    16741 aataaatcag aataagtttg gcaaagccca caggcgatac atcgttcagg tataagtgtg
    16801 attttcatgt tcatatttat attgtaataa gaaaagtaaa aaaaaacaag gagtaaggta
    16861 tggcaaaaga accgtggcaa gaagatatct atgatcaaga agaatcaaga gcagagcgtc
    16921 ggcatcgaaa ccacggaggg gctgatagga tggctaatcg tattttgacg atcctagcta
    16981 gtattttctt tgtaattgtg gtggtgatgg tcatcgttct catctatcta tcatcggggg
    17041 gaagtaatcg cacagcagcc ttaaaagact ttcatgattc tgatgcaagt gtagtacaaa
    17101 tctcatcttc aagcagttct cagcctgagc agagttcaga gccagaatct acttctagta
    17161 gttcagaaga agctgctaat cctgaaggaa cgattaaagt tctcgcagga gaaggggaag
    17221 cagctattgc cgctcgtgca ggaatctcca ttgctcagtt agaggccttg aatcctgggc
    17281 acatggctac aggatcttgg tttgctaatc caggtgatgt tataaaaata aaataggagc
    17341 cgatatgaaa acaattcaaa ttgctattga tggtcctgct tccagcggta agagtacggt
    17401 cgcaaagatt attgctaagg attttggatt cacctacctt gatacaggag ctatgtatcg
    17461 tgcagcgacc tatatggctc ttaagaacca attaggagtt gaagaagtcg aagcccttct
    17521 agccttgttg gaccagcatc caatcagctt tggacgttca gaaactggag accagcttgt
    17581 ttttgtagga gatgtggata ttacccatcc tatccgtgaa aatgaagtga ccaatcatgt
    17641 ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg gtttctctcc aacaagaaat
    17701 tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt ggaactgttg tattgccaca
    17761 agcagaattg aaaattttcc tagtagcttc tgttgatgag agagcagagc gtcgttacaa
    17821 ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc ctaaaaaagg aaattgctgc
    17881 gcgtgactac aaggatagtc atcgtgagac ttctcctctc aaacaagcag aggatgctgt
    17941 ctaccttgat acaactggtt tgaacattca agaagtagtt gaaaaaatca aagcagaagc
    18001 tgaaaaaaga atgtaaatgt agaaaagccg atagattgat atcggttttt ttctaaattt
    18061 gtcaaaatgc tgattttagg gtataatagt tgctgttcga gaaattttga ttttcaaaga
    18121 atagtgaatg atgataagga gaaaccatga acaatttacc aaattgtcca aaatgtaact
    18181 cagagtatgt ctacgaagac ggtgccctac tggtttgccc agagtgtgct catgagtgga
    18241 atcctgctga agttgcagaa gtagaagaag gtcttgtcgc tatcgatgcc aacggaaata
    18301 aattgactga tggtgataca gtaactctca tcaaggactt gaaagtaaaa ggtgcgccaa
    18361 aagatttgaa acaagggacg cgcgtgaaaa atatccgcat cgtagaaggc gatcacaata
    18421 tcgactgtaa gattgatggt tttggtgcca tgaaacttaa atcagagttt gtgaggaaga
    18481 tttaagcatg tcaaaacact ataaacttgt attttatagc cgtatcttct tgtttctagc
    18541 ggcttttacg ggagtttatc ttgaaattac taggcatggt ggttttggga tgcttctcta
    18601 ttacacggtt ctgtccaacc tcttggtaac tatttttacc ctttatcttc taaaggttat
    18661 gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg cgcttaaaag gtggggtcac
    18721 catgagtatc atgattacct gtgtgattta ccatttcctc ttggcgccca ttgcgactaa
    18781 tttctatacc ctagaaaatt tcctttgcca ctatatcgtt cccatctggt ttttagcgga
    18841 taccctcttt tttgacaaac agggtcaata caagatttgg gatccagcag tgtggaccat
    18901 tttacccttt ctgtatatga tgtttgctct ttttaatggc ttggttctaa aactcaatat
    18961 tccaaatgcc aaggataatc ctttccctta cttctttttg aatgtgaaca agggttggaa
    19021 tgttgtgttt aagtggtgtc tgattatctt tgttgcctat atggtagcag gatttatttt
    19081 ctactttatc aagcaaatca agagaaagtc atcctaatac tcttcgaaaa tctcttcaaa
    19141 ccacgtcagt ttccatctgc aacctcaaaa cactgttttg aacaacctgc gggtagcttc
    19201 ctagtttgct ctttgatttt cattgagtat aagatacaag ggattcattt tcgaatttaa
    19261 gaaggagtct acaaaccaat gaggcttctt cttttcttgc ttatttgata actatcaaaa
    19321 aagtagaaga ttaagagaaa tatagaaaga gatttcatga aacaattttt agaacgggcc
    19381 agcattttgg ctctctccct cgttttgatt acctcctttt ccatttcgag tgccctacca
    19441 gccatgtttg actattatca gggttattct aaggaacaaa ttgagctctt ggtgagcttg
    19501 ccttcctttg gaatcatgat gatgttactg ctaaatggtt tcttagaaaa aatatttcct
    19561 gagcgcttac agattagttt gggcttgctg attttatcat tgagcggtac agctcccttc
    19621 tggtaccaag cctatccctt tgtctttgga acacggcttc tctttggttt gggtcttggg
    19681 atgatcaatg ccaaggccat ttctattatc agtgaacgct accaaggaaa aaggcgaatt
    19741 cagatgttag ggctacgcgc ttctgcagag gtcgttggag cttctctcat taccttggcc
    19801 gtcggtcagt tgttggcctt tggttggaca gctatctttc tagcctatag tgctggattt
    19861 ttggtgctgc ccctttatct gctctttgtc ccttatggaa aatcaaagaa agaagtcaag
    19921 aaaagagcga aggaagcaag tcgtttaact cgagaaatga aaggcttgat ttttacctta
    19981 gctatcgaag cggcagttgt agtttgtacc aatacagcta ttaccatccg tattccaagt
    20041 ttgatggtgg aaagaggatt gggggatgcc cagttatcta gttttgttct tagtatcatg
    20101 cagttgatcg ggattgtggc tggggtgagt ttttctttct tgatttctat ctttaaagag
    20161 aaactgctcc tctggtctgg tattaccttt ggcttggggc aaatcgtgat tgccttgtct
    20221 tcatccttgt gggtggtagt agcaggaagt gttctggctg gatttgccta tagtgtagtc
    20281 ttgacgacgg tctttcaact tgtctctgaa cgaattccag ctaaactcct caatcaagca
    20341 acttcatttg ctgtattagg ctgtagtttc ggagccttta cgaccccatt cgttctaggt
    20401 gcaattggct tactaactca caatgggatg ttggtcttta gtatcttagg aggttggttg
    20461 attgtaatct ctatctttgt catgtaccta tttcagaaga gagcttagga ttgattccta
    20521 agtttttctt ttgatactca atgaaaatca aagagcaaac tatagttgat tgagtttgga
    20581 atagtacgct gtagctgcta aaatatttct agaaattaat ttgactttcc taatagagtt
    20641 gttcatatct tatttcaatc tactatagaa agctagccgc aggttgctca aaatagtgtg
    20701 ttgaggttgc agatggaaac tgacgtggtt tgaagagatt ttcgaagagt atgagatttt
    20761 tatacccata caatatttgt tttaggtcct tgtttacaga ctaatttctt gataaaatag
    20821 aggctatgac gagatataaa gcaactattt cctatgatgg ttatgccttt gctggctttc
    20881 agcgccagcc tcatgcgcgt agcgttcagg aagaaattga aaaaaccttg accagattaa
    20941 ataaagggca agccattact gttcacggtg ctggtaggac agatagtggg gttcatgccc
    21001 tgggacaggt cattcatttt gacctgcctt atcagatgga tgaggagaaa ctccgttttg
    21061 ccttggatac ccagtctcct gaagatattg atgtgatttc gattgagctt gtggcagatg
    21121 attttcattg ccgttatgcc aagcatagca agacctatga gtttactgtg gatagaggac
    21181 gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt tccctaccca ctcgatgtgg
    21241 aacgaatgca gattgcaatc aaaaagctag agggaaccca tgattttacc ggttttacag
    21301 cctctgggac tagtgtagag gataaggttc gcaccatcac agaagctagt ttaatagtcg
    21361 atgagacagg acaatttttg acctttacct tttcaggaaa tggtttcttg tataaacaga
    21421 ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa ccgcatgcca gtagagcaga
    21481 ttgatctcat cttggagaag aaggacaggc aacttgcagg tcccactgca gcaccaaatg
    21541 gtttgtattt aaaggagatt cgttatgaag aataatcgta ttttagcact ttctggaaat
    21601 gatattttta gtggtggtgg actgtcggct gatttggcta cctatacctt gaacgacttg
    21661 catgggtttg tagcagtgac ttgtttgaca gccttgacag aaaaaggatt tgaagtcttt
    21721 ccaactgatg ataccatttt tcaacatgaa ttagatagct tgcgtgatgt ggaatttggg
    21781 ggaattaaga ttggtcttct ccctactgtc agtgtggctg agaaggcctt ggactttatc
    21841 aaacaacgcc caggagtacc tgtggtgttg gatcctgtct tggtctgcaa ggaaacgcat
    21901 gatgtagctg tcagtgagct ctgccaagag ttgattcgct ttttccctta tgtcagtgtg
    21961 attacgccta atctcccaga agcagaatta ttatccggtc aggaaattaa aaccttggaa
    22021 gacatgaaaa ctgcagcgca gaaattgcat gatttaggag ctccagcagt cattatcaag
    22081 ggaggcaatc gtcttagtca ggacaaggct gtggatgtct tttatgatgg acagaccttt
    22141 actatcctag aaaatccagt tatccaaggc caaaatgctg gtgcaggttg tacctttgcc
    22201 tctagcattg ccagtcactt ggttaaaggt gataaacttt tgccagcagt agaaagctct
    22261 aaggctttcg tttatcgtgc tattgcacaa gcagatcagt atggagtaag acaatatgaa
    22321 gcaaacaaaa acaactaaaa tcgcccttgt atccctatta accgcccttt ctgtggtttt
    22381 aggttatttc ttaaaaatcc caacacctac aggaattcta actcttttag atgctggtgt
    22441 cttctttgcg gccttttact ttggtagtcg tgaaggagcg gtagtcggag gactagcaag
    22501 tttcttgctt gacctcttat caggctaccc tcagtggatg ttctttagct tggtcaacca
    22561 tggcttgcag ggatttttcg caggatttaa aggaaaaagt cagtggttag gccttatttt
    22621 agcaactatt gccatggtag ggggctacgc cttgggttct actttgatga atggctgggc
    22681 agcagccctc ccagaaattc taccaaattt tatgcaaaat atggtaggga tgattgtagg
    22741 atttattctt agtcaaagta tcaagaagat taagtaatac tcttcgaaaa tctcttcaaa
    22801 ccacgtcagc ttgtccttag tgtgtatatg ttactgactt ggtcagttct atccttaacc
    22861 tcaaaactat gtttcgagga gccttccgct aacttcccag tctgagtttc attgaatatt
    22921 aacgatactt tatcacataa agaggctgga tgaaaagtct tcacaatcaa aaaaacgcat
    22981 catatcaggt gtacatgaac tacaccccaa aagttagaca g
//
LOCUS       DAVDFK010000027        22829 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.27, whole genome shotgun sequence.
ACCESSION   DAVDFK010000027 DAVDFK010000000
VERSION     DAVDFK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.27"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..1119
                     /locus_tag="VUR04_001403"
     CDS             <1..1119
                     /locus_tag="VUR04_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5341286.1"
                     /translation="YDAPSCPECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFK
                     CYHCSRMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLN
                     DFHFKHDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQAVIRDHFLKY
                     DRAVRCRVKIITMDMFSPYYDLAKQLRFHIVQHLSRAMSRVRVQIMNQFHRKYHEYKA
                     IKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQILLFH
                     FQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLI
                     KLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(1282..1800)
                     /locus_tag="VUR04_001404"
     CDS             complement(1282..1800)
                     /locus_tag="VUR04_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET5341287.1"
                     /translation="MRTYENKEELKAEIEKTFEKYISEFDNIPENLKDKRVDEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(2027..2896)
                     /gene="rsmI"
                     /locus_tag="VUR04_001405"
     CDS             complement(2027..2896)
                     /gene="rsmI"
                     /locus_tag="VUR04_001405"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET5341288.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2899..3216)
                     /gene="yabA"
                     /locus_tag="VUR04_001406"
     CDS             complement(2899..3216)
                     /gene="yabA"
                     /locus_tag="VUR04_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET5341289.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(3256..4146)
                     /locus_tag="VUR04_001407"
     CDS             complement(3256..4146)
                     /locus_tag="VUR04_001407"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET5341290.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(4143..4781)
                     /locus_tag="VUR04_001408"
     CDS             complement(4143..4781)
                     /locus_tag="VUR04_001408"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET5341291.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(4897..5694)
                     /gene="proC"
                     /locus_tag="VUR04_001409"
     CDS             complement(4897..5694)
                     /gene="proC"
                     /locus_tag="VUR04_001409"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET5341292.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(5698..6960)
                     /locus_tag="VUR04_001410"
     CDS             complement(5698..6960)
                     /locus_tag="VUR04_001410"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET5341293.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAIA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(6970..8100)
                     /locus_tag="VUR04_001411"
     CDS             complement(6970..8100)
                     /locus_tag="VUR04_001411"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET5341294.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(8180..10063)
                     /gene="cbpE"
                     /locus_tag="VUR04_001412"
                     /gene_synonym="pce"
     CDS             complement(8180..10063)
                     /gene="cbpE"
                     /locus_tag="VUR04_001412"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET5341295.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     LEQ"
     gene            complement(10066..10953)
                     /locus_tag="VUR04_001413"
     CDS             complement(10066..10953)
                     /locus_tag="VUR04_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5341296.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10943..11404)
                     /locus_tag="VUR04_001414"
     CDS             complement(10943..11404)
                     /locus_tag="VUR04_001414"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET5341297.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(11401..12309)
                     /locus_tag="VUR04_001415"
     CDS             complement(11401..12309)
                     /locus_tag="VUR04_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET5341298.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            12302..12499
                     /locus_tag="VUR04_001416"
     CDS             12302..12499
                     /locus_tag="VUR04_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341299.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12551..13222)
                     /locus_tag="VUR04_001417"
     CDS             complement(12551..13222)
                     /locus_tag="VUR04_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5341300.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(13276..13497)
                     /locus_tag="VUR04_001418"
     CDS             complement(13276..13497)
                     /locus_tag="VUR04_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET5341301.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13666..14475
                     /locus_tag="VUR04_001419"
     CDS             13666..14475
                     /locus_tag="VUR04_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5341302.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSNWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASNYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14656..15531)
                     /gene="aguB"
                     /locus_tag="VUR04_001420"
     CDS             complement(14656..15531)
                     /gene="aguB"
                     /locus_tag="VUR04_001420"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET5341303.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15541..16626)
                     /gene="aguA"
                     /locus_tag="VUR04_001421"
     CDS             complement(15541..16626)
                     /gene="aguA"
                     /locus_tag="VUR04_001421"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET5341304.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16623..17750)
                     /gene="nspC"
                     /locus_tag="VUR04_001422"
     CDS             complement(16623..17750)
                     /gene="nspC"
                     /locus_tag="VUR04_001422"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET5341305.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17750..19009)
                     /locus_tag="VUR04_001423"
     CDS             complement(17750..19009)
                     /locus_tag="VUR04_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET5341306.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(19006..19866)
                     /gene="speE"
                     /locus_tag="VUR04_001424"
     CDS             complement(19006..19866)
                     /gene="speE"
                     /locus_tag="VUR04_001424"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET5341307.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            20247..20837
                     /locus_tag="VUR04_001425"
     CDS             20247..20837
                     /locus_tag="VUR04_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341308.1"
                     /translation="MSLRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIK
                     EFAKSLSLRKTKTDKKDAHGIALKLLSDPNREQFQHDNRQVELKILTRHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTAS
                     NSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSFS"
     gene            complement(20803..22278)
                     /locus_tag="VUR04_001426"
     CDS             complement(20803..22278)
                     /locus_tag="VUR04_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET5341309.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPIPAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         6642 a         5247 c         4109 g         6831 t
ORIGIN      
        1 tacgacgccc catcttgccc tgagtgcgga aaccaattga agaaatatga ctttcaaaaa
       61 ccgtctaaga ttccttacct tgagacaact ggtatgccta ctagaattct ccttagaaag
      121 cgtcgattca agtgctatca ctgttcaaga atgatggtcg ctgaaacttc tatcgtcaag
      181 aagaatcacc aaatccctcg tattatcaat caaaaaattg cgcaaaagtt aattgaaaag
      241 atttctatga ccgatattgc tcatcagctg gccatttcaa cttcaactgt cattcgaaag
      301 ctcaatgatt ttcactttaa acatgatttt tcttgtcttc ctgagattat gtcttgggat
      361 gagtatgctt ttacaaaggg aaagatgagc ttcattgcac aagattttaa caatctcaat
      421 atcatcactg ttcttgaggg tagaacacaa gctgtcatcc gagatcactt tcttaaatat
      481 gatagagccg tccgatgtcg cgtcaaaatc attactatgg atatgtttag cccttactat
      541 gacttggcta aacagcttcg ctttcacatt gtacaacatc ttagccgtgc tatgagtcgt
      601 gtgcgtgttc aaatcatgaa tcagtttcat cgaaaatacc atgaatacaa ggctatcaag
      661 cgctactgga aactcattca acaggatagc cgtaaactga gtgataagcg attttatcgt
      721 cctacttttc gtatgcactt aaccaataaa gagattttaa acaagctttt gagttattcg
      781 gaagacttga aacaccacta tcagctctat cagatcttgc tttttcactt tcagaataag
      841 gaaccagaga aatttttcgg gcttattgag gacaatctta agcaggttca tcctattttt
      901 cagactgtct ttaaaacctt cctcaaagat aaagaaaaga ttgtcaacgc ccttcaacta
      961 cactattcta atgccaaact ggaagcgacc aataatctca tcaaacttat caagcgcaat
     1021 gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga ttttcatcgc tctgaacatc
     1081 aaaaaagaaa ggacgaaatt tgtcctttct cgagcttagc ttttcttcaa cccactacag
     1141 ttgacaaaga gcctaaaaat attcaaagtc catgcaagat cacctccctt cttaaaaatt
     1201 tgcaaagaaa agacgatagt tttttcttct atcgactttg gtaaccattt ttatgaaatt
     1261 ttttaaagtt aaaaatataa tttataatac tatcttcttc cattttctga ttttagttct
     1321 gaaagttcca aaaggtgcaa ccgtatttac atgaataaac ttatacactt cccaagtcgc
     1381 tgttttagtc gcttcatcag cccactttct catatgcggt tcaaataatt cttcctcact
     1441 caacgaatca atcattgcag agatagaatg aatattttca tttaattttg ctttcaactc
     1501 ttgcagagat aaatgagcgt aggtatccgt gaaccactga tataattcac caagttgatt
     1561 ccatttaaat ttatccgatg gtgtttttac ttgaagcccc tttctttcat cttcttccca
     1621 tttaagaacc aagttggtcc agccaacctg ataagcaagg ttttctgctg gagttctatc
     1681 aacttcatca actctcttat cttttaaatt ttctggaata ttatcaaatt ctgaaatata
     1741 tttctcaaat gttttctcta tctcagcttt tagttcttct ttattttcgt atgttcgcaa
     1801 aaaatcacct tctttctgat ttatcaatcc tttgatttaa aatgacctta tttttctatt
     1861 tataccttct aagaacgcta taactgctgc tccaaccatc ggtattccgt atgggcttaa
     1921 taaaaaactt aataccaaag cttctatacc aagtgataca tcttcatatt atcatcacta
     1981 attaagttaa acagaaacag acagaattat tacatcctgt ctccctttat tgtttttctt
     2041 cccagtcgtg gtaggcagcg tagagctgac ttttattcca ctggtaaatc ttagcgactt
     2101 ccttgatagc ttggtttttc ttcacacctt gctggatgcg ggtttgaatt tctacgaaca
     2161 agtcttcctc gtccttttcc tccacaccct gactggcacc ctcaacaatg agaagacatt
     2221 cgcccttgag tggcgtttca gcaatgcttt ctaataactc agagatagta cctcgttggt
     2281 attcttcata gattttggtc aattccctga ccaagacaac ggagcggtca ccgtagactt
     2341 ctaacatatt ttccaacgtg tctgctacac gatgaggtga ttcataaaaa atctgtgttt
     2401 caggataatc ttttttcaag ccaaaaaatt gcttctgctg acctgatttt ctcggtaaaa
     2461 aaccgtaaaa gatatgtggc tgtggcgcta aaccactggc aatcaaggca gaaattcctg
     2521 cagaggcacc tggaactgtc acaactgcaa tttcttcctc aatagctgcc ttaactaaat
     2581 catgaccagg gtctgaaatg ctaggcaaac cggcatcaga gacctgagca atactttgcc
     2641 ctgctttcaa gaaaccaatc aaatcaggaa ttttttcctt ggcattgtgc tcatgaaaac
     2701 tgatctgctt ggtggaaatg tcaaaatgct tgagcaaaag ccctgtattg cgcgtatcct
     2761 cagcagcaat ccagtccact tctttcaagg tctggatagc acgaaaagtc atatcatcta
     2821 gattgccaat cggcgttgcc actagataca gcttgccata gggagactgc cccttaaaac
     2881 ttttttgaat ttgcatgctt actccctgta taacaactca tcacagaaca tacattcttc
     2941 gtcctgctct cgacgttgtc cataaaaatc attacatacg tgaaatccat cacggtaaat
     3001 acgacggaca ctttcgcgaa catgcttggc cttgacggga gcgtctgctt ccacctcacc
     3061 caagcgttct cgcaacttac tattttccaa gcgaagagct gtattttctt ctaccaagct
     3121 cttgagattt ttcttgatgg cttccacatc ggctaaggtt accaataatt gttgggaaaa
     3181 atcatccagc gcgtcaaata attctttttt gtccataaaa cagccctttc ctttctttat
     3241 cattcatttt tgagtttata tttctttcaa gaccagatat tccatggcat tttgaaagct
     3301 gacattagct tgccacattt ttctagcttc tagtaaatct tgtagaatca ctcttactct
     3361 tacctgcaag aggtcctgcc cacagagaac ttcaagaatc cgtaaaacct gatcctgttt
     3421 ttccttatca tctgccaagt tggctaattt ggcaacctgt agataacttt cttttttctt
     3481 agctactaac caagtcagca ggcgttcact ttcatcgacc aaggtccaaa aacttgcctg
     3541 attagccaac ttttctgctt cagctcgcga ttgactaaac ttagctaaaa gagtcgcttt
     3601 tttcttaaca agtcccattt gttctaagag taagataagt ttttcttctt gctttttaaa
     3661 gtggaagatc tgagtccgac ttcggattgt cggtaacatc ttttcctcat cgctagtcaa
     3721 gaagaaaata taaacttcac tctggggttc ttcgatgacc ttgagcagag aattggctgc
     3781 gttgggatgc attttatccg cttgctcgat aataaagacc tgttgctggc tttcaatccc
     3841 tgcttgagaa aactgtccca ccaattcccg aatgcgttct gtcttgatga cctgattgac
     3901 tggcttaatc aaggtgacat ctggaaactc ttcctgttca atcagcttgc aacttcggca
     3961 tttctcacat ggtaagacgc caactttatc cgtacaaaag aggctcttag ctaaaaattg
     4021 cgccatttcc aagcttccaa agaaacctga aaagagatag gcgtgattga gctggtcttg
     4081 ttctaagata cggacaaaac ggtcaaactg agctggttgc caagccttta gttgatcttg
     4141 tttcatttgg ccaagtccat tccgtcaaac aagacagcct tggtagtttc cacaacttgc
     4201 tccaaaggga gactagcatc aatcttgaca atgcgatttc cttctttttc caggagagaa
     4261 aggtagcctt gacggacttt cttgtgcaat tccaaacctt ccaagtccag acgattgacc
     4321 tcgcggtcac tattcgcagc aatgcgagcc agcccttctt ccacctcgat gtcaaaatag
     4381 agtgtcaaat cgggtttgag gccatctgtc gcaaactgat tgagccagtc aatggcttca
     4441 atatctaagc cacgaccaaa tccctgatag gcaacagaac tatcgataaa acgatccatg
     4501 atgaccaact tgccagcttc aagggctgga agaacttttt ccaccaaatg ctgtctgcga
     4561 ctggcaatat agagaagtag ctctgtttta gcatccatct gagtatgact tggatccaaa
     4621 atcacttccc gaatcttctc cccaatcaag actccgccag gttcacgggt cgtcagcacc
     4681 tttactcctt tttcctctaa aattggtagc agagcctcta aaacactggt cttgcctgct
     4741 ccctctggtc cctcaagaga gactaaaaat ccttttgaca tgtctaactc atttcttttt
     4801 tactacttct attctatcaa aaaaataggg gtttgtgaca atctttttgt gtcttctcat
     4861 ttcagccacc ataaaagagg cagtcaaagc tacctcttat ttacctagtt cttgtgttcg
     4921 tttataggct tgatgaactg cctccatgac tatgcctcga aaagcatgcg cttctaggct
     4981 tgctacgcca gcaatagtcg aaccgcctgg actacaaact tgatctttca aaactccagg
     5041 atgttgctgg ctttctagga ccaattgccc agctcctacc acagtttggg ctgccatttt
     5101 caaggctgtt tctcgtggta atcccgtctg aacacctgca tctgccaaag cctcaataaa
     5161 gagatagaca aaggctggtc cacagcctgc aagacctgtc gctgcattga ttaagctttc
     5221 tcctaattca accaagagac cagccttgga taaaagctga caaaagagct cactgtcctc
     5281 agccctgcaa ttaggagaca aggcataact aattactcct tgcccgatag aagcaggggt
     5341 attaggcatc atacgaataa ttcggtgttg acttgggata agacttgcta gtttttctaa
     5401 ggtcaatcca gctgccatcg aaatcaaaag aagactttct cttttttcaa ggatggtctg
     5461 gtattgagaa agcagttcag aaaactgagc aggcttaact cctagaaaaa tcacatctgc
     5521 ttctgcaaac atttcttcat tgctggaagc ctgaccacca aagtctgcaa tgaaagcatc
     5581 taccttagct tgactacgat tggcaaggag aatctcatct gacgtcctag tctgcaagac
     5641 agattttgcc aagctagcac ccatattccc caaaccgata aatccaatct tcatctctta
     5701 ctcccttatc tgcccgtcac cagcaaccac atacttgtag ctggtcaact ctttcaagcc
     5761 cattggacca cgcgcgtgca atttctgagt agaaatcccc atttcacaac caagaccaaa
     5821 ttgtcctcca tctgtgaaac gagttgaggc attaacatac accgctgcag agtccacttg
     5881 atctgtaaag tatgctgcag cttcagcatt ttccgtcaca atggcatccg aatgatgggt
     5941 actgtgggat tcaatatgcg caatcgcttc ttctaaactg ctcacaacct taacagctag
     6001 aatatagtct aaaaactcgg tatcaaagtc ttgtgcttga gcagcttgac ctgaaacaaa
     6061 ctggcttgct ttgctatcta ggcggaattg aattggttcc aacccagctt cttttcgctc
     6121 tgcaaccagc atttgatcca agcgaggaag gatgcttgct gccttgtctt catgaaccag
     6181 cagaacctcc atggcattac aaacagaagg acgactggtt ttagcattgt tgatgataga
     6241 cagcgccttg tcttcgtctg catccttatc cacatagaca tggacaatcc cagtccctgt
     6301 ctcgataaca ggtacaatcg cattctcaac cactgcattg atcaagccag ctcctccacg
     6361 aggaatgagg aggtctagat agcccttggc cttcatcata gcataactac tttcatggct
     6421 agtatcttcc accagttgaa tcacatttgg gtgaatagta gtcgtctcca agcccttctt
     6481 caaggctgtg acaatggcat gggttgtttg ataggcatcc ttaccactac gaagaacaac
     6541 cgcatttcca ctcttaagag tcaaagcagc cgcatcagac gtcacatttg gacggctttc
     6601 atagataata ccgatgacac ccatagctac acgttttttt gtgataacca aaccattttc
     6661 aagctgactt gtttctaaaa cttcaccgat tggatctggt aaggcaacca cttcacgaat
     6721 tcctcttgcc atcgcttcta tacgatctgc atccaaataa agacgatcca acatcacatc
     6781 tgagattttc cccttagccg ctgccatatc gagggcatta gccgctaaaa tttcctcagt
     6841 agcagccact aagtgatcag ccatggctag caaggcttga tttttcactt cttcactagc
     6901 tgtgttaatc gattttttaa cagcctgtac ctgttcaaat tgttcttgtc tactcaccat
     6961 agtttacctc taaaattctg taaaaagtag ttggatttca ggagtaatgg aaatccagtc
     7021 gtcacggtaa atcaagacac ccttggcttt ttgagaacgc aacatatcct ccaaagcaga
     7081 tgctccaaat tgcacgcgtc cttttccaag tgattttcca ctttccttgt caaatactgt
     7141 cacgatatca ccgtaagaaa aggctccttc tgcttcaacg ataccagata agagaagact
     7201 ctttccatgt tgagagagag cttccgcagc ccctttatca acccaaatag aaccttgact
     7261 ctgagcatag aaggcaagcc attgtttctg ggtacgaagc cccttctctt gagcaacaaa
     7321 gtaagaacca tcctcggtct cctctgccgc ctcaatcatg gaatctgatt tcaaggatga
     7381 gcagatataa acaggaactc ctgattccgt cgcgatagtt gcagccttga ttttggttaa
     7441 cataccccca gttccgtttg acgaaccagc tccaccagcc atatcaataa tctcacgatt
     7501 gatggtctcg attctctcca agcgtttggc tcttggatct gaattaggat ttccagtata
     7561 gagaccgtcc acatctgtca agagaaccaa aaggtctgct tggaccatcg ccgctacttg
     7621 ggcacttaga gtgtcattgt ccccaacctt gagctcatca ataacgacac tatcattctc
     7681 attgatgata ggaattgccc cacggttgag caaaaccgac aaagcctgat gggcattttt
     7741 ataacgacgc ttatccacaa agtcatcttg ggtcagcaag atttgtgcag aaacgatttg
     7801 acgcaagaga agattggtcg tatattcttc caacaaaagt ccctgcccta ccgctgctga
     7861 agcctgttta tcagcaattt tagtcggacg ctttttaaat cctaaggctc caaaaccagc
     7921 cgcaatggca cctgaagaca ccaaaatcaa ctcatgacca gcctcgtgca gcatagccaa
     7981 ctgctgggta atatccttta ccttactacg tgataaactt ccatcctcat ttgtcagaga
     8041 agaagtaccc accttaaaga caatccgttt gtatttcata gtctcactcc gattattcat
     8101 atttatccat tataacatga ataacaggaa atagaaaaga gttgatagga aaaagaaggc
     8161 cctaaaacct tcttttctac tactgttcta attccgattt gtttacactc gtttcagagc
     8221 tttgtgaagt tgaggatgtc aaatcttgac tagttgaaga atttgtaaca ctttcatgtt
     8281 gactcgtttc tttattttca agatcctttt tcactacttc tttggattct tttatttctg
     8341 aatgacttgt agttttaatt gtagcagatt tctcgatcgg aacatccact aaccaggcac
     8401 cacttgaatc cacagtatag ccttctggtg tcttaccatt cacaagtaat tgaccatttt
     8461 ctttcaagaa gtaccattta tccttgtctt taatccaacc tatagctcgt gaaccatctg
     8521 tcttgtagaa ataccaatca tttgcctttt taagccagcc ttgcttcata gctcctgatt
     8581 cttctagata gtaatgatgt ccagcaactt ctatctcacc tgtcttcatg ataccagtag
     8641 aatccatata gtaccaggct tctttatctt ttacccagcc cgttttcatt tcccctgatg
     8701 gagcaaagta ataccattgc cccttatatt gaagccaacc tgtcttcata gagccatcaa
     8761 catccaaata ataccactgc tctttatctt gaatccaacc aatttccatc tggttttctt
     8821 tgttaaaata ataccagatt ccagcgattt tcttccaatt tttagcagca acaccagagt
     8881 ctgtcaaata gaaccaacga ttgttccatt ttttccattg attctgtaat aagatacccg
     8941 tttggttaaa gtaataccat tcacccttaa tttcattcca accgacagca tattctcctg
     9001 tagaatcagg cgcttgatac caccagtttc catatgaact cttatgccaa ccagcttgaa
     9061 aacttggaat aggcttgtag gaagttgaaa tgtttactaa accgtctttt cgaatatcaa
     9121 aaactgttgc atcatagtct ttgctggctg cgttgattct ctcaattcct cgttctttga
     9181 gccaattaac atactcacta tcaacaccat ttttccaagg tagactatcc gaagtttgaa
     9241 caatcaaact cggactcaaa tttttaatga aatccttggt atttgatttg ttggtatcat
     9301 ggtgatgatt aaacttcatc aaatcaactt ttccaatgag aggaccatac ttgtcttctg
     9361 ctccatgaac attatctaaa tcgcccccaa ggtaaatttt cttgccattg actttcacca
     9421 cgctaatcaa ggaattggaa ttgtcatccc aaattttctt taattcaccc gatgaatcag
     9481 tttcattttc ataattatag agctgaatat ccatgtcccc aaactgaaaa tgagcatccc
     9541 cttgtgtgat attttgaata actgaaacac ctgtttctgc agcagtctgt aaaaccttat
     9601 catagccata cagattatcc catagacgtt cagaattagt aatacgacta tcactatatt
     9661 tcttaagata gactcggtca actggatagg tagacagtaa ttcatcaaca tttccaatat
     9721 gatcactgtg ggtatgggtc accaaaataa aatcaagttt ttggacaccc aattccttca
     9781 aacgacgaaa gacacggtct gttagaacat gcttataaga cgtttcaatt ccttctctcc
     9841 atggatagcg agaatcactt ccatctggga aatcataatc ttctcctgta tccaccatgg
     9901 caaaatgtcc attgctttca agaataatcg catcactgcc accttcttga acattgataa
     9961 agtggatttt atttcctgaa ctttcttgag cctgaacatt cccataccat gacaaaccta
    10021 aaaaagcgcc tacaagtgct aaactagtta atttcttttt cattcttact ttctcaatct
    10081 ctccaaggtt tccttaaaaa tctctgggat atctgcttta aattccaagg tcttacctgt
    10141 tctcggatga gtaaaaccta aagtcttggc atgaagaaat tgtccatgtc ctttcaaagt
    10201 cttgcgagga ccatagacct catcaccagc gactggatgg ccgatataag ccatgtggac
    10261 acggatttga tgagtgcgcc ctgtctccag ttgcaactct actaagctat aatcgccaaa
    10321 gcgttccaag acgtgaaaac gcgtcactgc aggcttccct ttagcagtta cagcctgttt
    10381 cttacggtct ttttcactcc ggccaatcgg cgcttcaatt acaccacgat cattaggcag
    10441 atttccatga acaatcgccc aatatttgcg gagagacttt ttatccttga gttcttgggc
    10501 aagtgctaga tgcgcatcat cgtttttagc aatcatgaga agacctgacg tatccttatc
    10561 aatacggtga acaatccctg gacgcagaac cccattgata cccgacaagt ccttaatatg
    10621 atacatgagg gcatttacta gggttccact ggtatgacca gcactcgggt gcacaaccat
    10681 tccctgaggt ttgttaacga cagccacatc ctcatcttgg tagactattt ctagcggaag
    10741 atcctcagcc acatactcta atacctctgg ttctggcaca tggtaagtga cgacatcacc
    10801 ctcttggact gtgtatttag ctttcttgac ttgaccattg accaagacct ggcctgattt
    10861 aatttgttca ttcgcgagac tacgtgataa ttctgacaaa tctgacaaag ccttatccaa
    10921 acgcagacca ccagtttcaa ttttaatttc catttatttc ctcttttagc attgcaatca
    10981 ataaaataat cactccaacc gtcagatagc tatctgccac attgaaaatt gcaaagttga
    11041 taaagtcaag gtggaacata tccacaacaa agccctgact gaccctgtca ataaagtttc
    11101 caagaccacc cgcgattatt agagtcaaac ccaagaccat ccagaatgag tcctccatgt
    11161 gtttatgtaa ataccaaatg gcacctatca cgacaaccag agtaatgaca gcgaataaca
    11221 actgctgatc ttgtaagata gaaaaggctg cacctcgatt ttgcaggtag gtcaagctaa
    11281 cgaaattggg gatccaggag cgcacttcac ccagtggaat ctgctggacg atataggatt
    11341 tgaccaactg atccagccca atcaaaagca gtacaatgac tgccactatt gctctttttt
    11401 tcatgatttc ctcttttgat caaaatattc ttgcatgact tctacgaaga gagtcccagc
    11461 ttgactaagc tccacttctt cacgtttaac atagaccatg cggttatcta ggttatcctt
    11521 gagacgaata actgtaatgc cattaacact gtcactatct aaaaatccag aacctgtcgc
    11581 ataggcgtcc gtccgctcca aaataccatt caaggtggca cggtctgtca cattaaacat
    11641 ctgtgagcta gcgctggtat caacaaagtt ctctgaataa taaaggtact cgtctttctc
    11701 ttgagtgaaa cgaaccgttg gtaaatccgc taaatcctcc atgactaatt cctctttctg
    11761 ggctaaagga tgaccctcac agagataaat atgggtatgg aaaggaatca attcgatgac
    11821 ctccagacct aacttttcaa cccgttgcat aatccccttt ttattttgat tgttgaggta
    11881 gataatccca atctcactat gcccttgcgc cacttcatct aatatttgaa cagtagttga
    11941 ttcaaaaata cggaagttct tatagtcagg atagcgctct gaaaaggccg taatagttgg
    12001 tggtaagaag tcatagtgct ggctagcaac ggaaaattca tctttttctt cttcaggatt
    12061 ggcatactga ttttgaaaaa tatcaaatcc tttaaccaat tcttgcgctt tttcataaaa
    12121 ttccatccca cgacgggtca agaaagtccc tgagctggtc cgacggaaaa tcttaaagcc
    12181 caactctttt tccaaatcac gaacagaaat agacagactc ggctgactaa catacatctt
    12241 ttcagcagct tcacgaaaag taccactatt ggcaatagcc acaacatagc gtaattgttg
    12301 aatgttcatc ttctaccccc aacttcttta tcttttcatt ataccatatt ttagaagttt
    12361 tccaaaaagg aaaaaagaac atcctattct tcttaactat cttcactatc tgcctttctc
    12421 acgccaatct tattttcaaa atcaattcaa aaaaataagt ggctacacac cacttcagta
    12481 tcggaaagaa aaacgttgac tatttgtgaa aaaagaaaat gccggaaaat tccgacattt
    12541 ttttagtaag ctaacttcct gaaaatagga gtaaccaaac atcccagaag gcagtgatat
    12601 tgatgagaat atgaactagt attggatagt agagattttt agtcatgcga tacaatagag
    12661 ctaaaataag acctccacta gcataaatga aaaaagcaag aggagttaaa gcaaaattga
    12721 tatgaatata accgaaaata atagcagaaa gcaaaacatc tccgtaccaa ggtgagtttt
    12781 tgaaaaaggt tgtcataagc acacctcgat aaatcaattc ctcagcaata ggggcgatga
    12841 agcaaacgat gagcaagaaa taagggaact cctgtctccc catcatttct accgtttcat
    12901 tcaaagaaat ctgatttgaa gacagggata tgaaatacga aaagaggaag tcagacatat
    12961 atgaaatgat gtagcccagt aaaaggtaga tgaagtacct cagctgccac ttgaaatgaa
    13021 aaattttctt tcctgcaaaa accagtagat agatgaccgc taagaaaaga actccgctct
    13081 ccatcaaaag cagaatctga aaaaattcac gacttgctgg tagatagggc tttgcgaggt
    13141 gattgaaaac tctccaaaac caagttgatt tgtaaaaaat taaggacaat gctagtaaaa
    13201 tttgaatagc ccgttttttc atattaaatt ctctgctttc tccacttgtt tcttcatatt
    13261 actaataaat tttacttaaa atctcgcagc acttcctttg caaagatgat tgcctcctcc
    13321 aatatatcct aaatcatagg tgcctctggg acaaaatcca tgaaccggca gagttaatac
    13381 tggttctatt tcccaatcgt acctaccatt aggattttta ccatatggat ctgctccacc
    13441 ttgtatcagc tctaattctt catttgttag atttatattt tttgtcatta aaatcatgat
    13501 atatttcctc cattattctt cagattagtt gagtaatctg atactcatac ctacttacaa
    13561 aaaaactatt atattaagtt ggttttttaa tttgtctcaa gctttctatc aatttcttct
    13621 ccaaaatatg ctataataat agcaaaagat aaagaaggaa gacctatgat taaactacta
    13681 gccttggata tggacggcac cctcctcaat gaagccaagg aaatcccaca agctcacatt
    13741 actgctattc acaaagccat tgaaaaaggt gtcaaactgg ttctctgtac gggtcgccct
    13801 cttttcggtg tcctccccta ctacaaaaaa ctggagcttg acctccagaa cgaatatatt
    13861 attgttaaca acggttgttc aactcaccag accagtaatt ggagtctagt tgactggaaa
    13921 gaactgagtc cagctgacat cgaatacctc tatgaccttg ctgaaaagag tgatgttcag
    13981 ttgacacttt ttgacgagtc acattatttt gttctcggtg gcaaacccaa tcaagttatt
    14041 gaaaatgatg ctaaactagt attttcagac ctgactgaaa tttctcttga agaagcgact
    14101 agtggaaagt tacggatgtt ccaaggtatg tttttaggaa caaaagaaca aacagacgat
    14161 tttgagcagc gttttgctga agagctttgc caacgattca gtggagttcg ttcgcagcct
    14221 gtcatttatg aagcaatgcc gcttggaacg acaaaggcta ctgctctttc acgactagct
    14281 gagattttga agattgattc ctcagagatt atggccatgg gcgatgctaa taacgatatc
    14341 gaaatgctcc agtttgcagg gcttgggatt gcaatgggaa atgccagcaa ttatgtcaaa
    14401 tctcttgcgg atgccgttac ctcaagcaac gaagaagacg gcgttgcgcg tgctattgag
    14461 aaatatattc tataaaaaag aaaagcaaat agacagaagt tactgctatt tgcttttttg
    14521 ctaatatttt aaaatacgga ctaatcaata gacaagaata gcgaatcata aaaatcgatt
    14581 tactagatgc catagtatct tatagttgct aataagaagt tagtctagca gaatgaatct
    14641 ctcatttctc ccacactaat ctgtaatttg tctatacatt tctggtcttc tatctcgaaa
    14701 caagccccag tttaggcgtt cacttgctcc cttgtctagg tcataagtag ctaacagaac
    14761 agcttcttct tgtctttcag ctcgttctag aatagctcct gtttcatccg tcataaagga
    14821 ggaaccgtag aagtcaagac tggaactctg tccgccattt tcctcactag gagtaacctc
    14881 ctctaaacca taacgattgg ctgcgatgac tggaacaata ttcgctgctg cgtgcccttg
    14941 catagtacgt tgccagtgac cacaactatc tgtatccaaa atcggctctg aaccgatggc
    15001 tgttggataa aagagcaatt ctgccccatt cagagcaaga cagcgggctg tttcggggaa
    15061 ccattgatcc caacagatac cgataccaat cttagcatag cgagtattcc agaccttgaa
    15121 accagtgtta ccaggcgtga aatagaattt ttcttgataa taatggtcat ctggtatgtg
    15181 ggtctttcga taaacgccca gcacttcccc atctgcatca atgacggcaa tagagttata
    15241 caagacatta ccatcttttt catagaaact gattggtaaa acaacttgta gttccttagc
    15301 aatcacctta aaatgctgaa tggcagtatt ttccgctaca gattgggcat actggtagta
    15361 gtcatactga cgttcctgac agaaataggg atgttcaaac aactcgggca agagaataat
    15421 ttgggctcct tgctcagcag cctgacgtac taaacgctct gcggtttgga tatttgttgc
    15481 cacatcctta gcgcattgca tctgaatggt tgcaactctt acatttctca tctttttctc
    15541 ctattctgga atttgttggg tgatacagtg gatattgcca ccacctaaga gaatatctct
    15601 ggctggtatt ccgacaactt tacggtctgg gaaacacttg ctgaggatat ctaaggccac
    15661 ttggtcgttt acatcctcaa actgtggaac caagacagcc ttgttggcga tataaaagtt
    15721 tacgtaggaa gctgctagtc gttcacctgc gtatcgcttt tcttctcctt cttcatagat
    15781 gtagcctggc aaatcttctt ctgtcacaac ttgtcgaact gcagggatag gcaatttatg
    15841 aatggtgaag tgacaacctt ttgcatctgt ttcctgttct aagagttcga gatctgcttt
    15901 tgacatggca tactggggat cattttcgtc atctgtccaa gccaaaacaa gctcagcagg
    15961 accaacaaag gcagcaacat tatcgacgtg ttcattggtt tcatcctgat aaataccata
    16021 aggaagccaa ataacttttt cagcaccaag actttctaat aatgtgtttt caatctcctc
    16081 tttagtcaag ttaggattgc gaccaggact aagcaagcaa ctttcagtta cgagaatagt
    16141 tccttgacca tcgctatgga ttgcgcctcc ttccagtaca aaaggtttag catcatagac
    16201 aggcctttcc aaggcctcag caaaacgact ggctacttgg tcatcctctt cataatcttg
    16261 ataaagacca tcataggtgc ctccccaagc attgaaggcc caatccacgg ctaatttctt
    16321 acctttatca ttgacgagaa tggttgggcc agtatcacgc gcccaggcat cattggtggg
    16381 aatgtctaaa taaacaacct tgtctccaag ataggattgg gcttcagata gataggcctg
    16441 ctccaccaaa agatagactc tttccccttc tgctatggtc tcgatgatct gagtaaatgc
    16501 tcttttagca gcctttcctt gaaaaggcca tgatcctggt cgagtcggcc atatcatgag
    16561 ggtaccatga tggggttcgt actctgctgg catgtgatag cctaattttt ttggactgtc
    16621 catcatgata atctcccttt aaagtcttga tagccaaaag ctttgagtaa gctacagtct
    16681 ccctgttcgt ccatgagata gagacttggc aatccaatac cattaaaggt attatttttg
    16741 acaaaagaat aaatggccat gtcttgaaaa taaagtctgt ctccgatttg gactggattt
    16801 tcaaaactat aatcaccaat cacatcgcca gtcagacagg tattagaaga aagtctgtag
    16861 gtatgggctt tttcctgtgc ctcaaagcca tttctcaaag gtggacgata gggcatctca
    16921 agtacatcag gcatatggca ggtcgcagag gcgtctaaaa ccaagatttc cataccgttt
    16981 tctacaatat ctaatacctc agttgctaaa taacccgcat taagcgcaat ggcttcacca
    17041 ggctcgatat agatttcaag attgtaagtt tttcggatac gcttgatttc tgaaatcagc
    17101 aaatccacat cgtaaccttc tcttgtaata tgatgaccac cacccatatt gagccatttt
    17161 acctcatgta agtagggacc aaattgttct tctactgctt tcaaagttgt ttgtaaatca
    17221 tctgctccct gctcgcaaag ggtatgaaaa tgaagtccgt caaccaaatc tagcaaatca
    17281 ctcggaatct tgtctatagt aactccaaag cgagaacctg gtgcacaagg gtcatagagc
    17341 gcgtgatctc cttgagttga acactgaggg ttgaggcgca aaccaacact gacaccagcc
    17401 tctcgacaac gagccccatg cttacgcaac tgtctctctg agttaaagac gatatggtct
    17461 gttatcccaa gcaattcctc caagtctgca tccttgaaag caggcgcaaa tacatggact
    17521 tcaccaggaa attcttccct tgccaatttg gcctcataga gtccactagc tgtcgtacct
    17581 gatagatact ggctaatcaa gggataagtt ttgtagaggg aatatgcctt ctgggcaagc
    17641 aagaccttgc aaccggcctc ttcttgtaca tattgtagaa tgcggcaatt agcttctaac
    17701 ttggccaagt caataacata ggctggtgtt ggtacttgtt ctaacttcat tagtccacca
    17761 tttgtggatt ttcaaccaca acccatggca aaccatactc attcaaagct tccatgaatg
    17821 gatctggatc taactcctca aggttataca ctccagcttg tttccaagtt ccgttcatga
    17881 ctaattttgt cccaatcatg gctggaacgc ctgtcgtgta tgaaattgct tgtgacccga
    17941 cttctgcata gcactcttga tggtcgcaaa cattgtagat gtagatagtc ttttcaacgc
    18001 catctttgac acctgtaaag atacatccaa tattggtttt acctacagta cgtgggccaa
    18061 ggctagcagg atctggaagc aaggctttca aaaattgaat tggaacaatt tcttggccgt
    18121 taaagttaat ggtatccgta cgaaggagtc caacattttc aagacatttc atgtgcgtca
    18181 agtaagattg accaaaagtc ataaagaaac gaatgcgttt gacacctgga atgttcttgg
    18241 ccaatgattc gatttcttca tggtgaagga gatacatatc tttttgtcca acttgaggga
    18301 aatcatactc acgcttgata gacatagctt cgacttcgac ccatttccca tcttcccagt
    18361 aagaacctgg cgcagaaacc tcacggagat taatttctgg attaaagttg gttgcaaatg
    18421 gataaccgtg gtcaccgcca ttacagtcta aaatgtcgat ataatggatt tcatcaaaat
    18481 agtgtttgag ggcataagct gaaaagacac tagttacacc tgggtcaaaa ccagaaccaa
    18541 gaagagcagt caagcctgct tctttgaatt tctcttgata agcccactgc catgagtagt
    18601 caaagtaggc tgtaaaacca agttccttac aacgtttttc gtagatagca cgccactcag
    18661 ggtcttctgt gtcttctgct tcgtagttgg ctgtatcgat atagtgaaca cctgttgcca
    18721 aacaagcatc cataatggtt aaatcttgat aaggcagagc tacattcaaa acagcttctg
    18781 gtttgtagct ttcaatcaag gtaatgacct cttctacctt gtcagcatca agtgctgcag
    18841 tttcaatttt agtacttgtt ttgccttcta gcttcgcttt caagtcatcg cattttgact
    18901 tggtacggct agcaatcata atctctgtaa acgtttcgct atcttgacaa atctttgaaa
    18961 tagcaacttg ggcaacgccc ccacaaccaa taactagtaa acgactcatt tttttccttc
    19021 ctcttcttct aaaatgtcct caacatactt gggcaacata aaggctccca cgtgtaagtt
    19081 tgcagtgtag tattctgtga aaagctggcg ttttttccag ccttccttgt caaaatcttt
    19141 gacagggtga tattttttcg atgcaaatcc aaacaaccaa tagccagctg ggctagttgg
    19201 aatatgggcc tgataaaccc gactgattgg aaaggcttga ttgaccttgc ggtgcatgct
    19261 tcggcaggcc gactcatcct cgtcaaagaa gggactccca tgctggtaaa tcatgatgcc
    19321 gtcttccttc agagctcgat aactattgcc gtagaattcc ttggtaaaga gtccttccgt
    19381 atggccaaat ggatctgtcg catcgttgat gataatatca tagtcatctt cgcagtttcg
    19441 caaaaagcgt agcccatttt ggtagtaaat agtaacacga ggatcatcta ggcctgcagc
    19501 aaagtctggg aaatactcac gacagacctc gaccaacatc tcatccggtt ccacgatatc
    19561 gatttgttcc agttcaggat agagtgttaa tacttgggca acaccgccgt caccaccccc
    19621 aataaccaat actttctttg gatttgggtg gacagccatg ggaacgtgga cggtcatttc
    19681 attgtagacg aaatcatccg catctgagaa caagacatgg ccatttaaaa tcagtatttt
    19741 cccaaaagct ggcgtatcca agacttcgat atcctgccat tcactttttc cagcgtaaag
    19801 ttgcttggct gttctcagag acaatttgac atctggagta tgaacttcag aaaaccataa
    19861 atccatctat ttctccttat attatattta acgcagttag ctactgccaa agcccaagtg
    19921 gtatacttgg aataagccac tgtggattag ttcatttcct ccaatcgctt gacgatttcc
    19981 gaaagggtct aaccacagct ttttgtttca attggtaatg agtttgataa cgcatagacg
    20041 tttgatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta gacttgaaat
    20101 actatatctg gagatactcc catgctttat gtgggcattg atgtcgctaa aaataaacac
    20161 gatgttacag ccttgaatgt tcgaggaaaa ctgttcttaa accactcact ttttcaaata
    20221 ataaagctgg ttttgaactc ttagatctgt ctcttcgaca gctcaaccaa gactgtctca
    20281 tcgctcttga agataccgga cattatgcct ttaatctact gaacttcctg catgaacaag
    20341 gatataaagt ttacacctac actcctttgc tcatcaagga atttgccaaa tcattatcac
    20401 ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg
    20461 accccaatcg tgaacaattt caacacgata atcggcaagt agaactaaaa atactgacta
    20521 gacatattca tcgtctcaag aaaaaacagt ctgattggaa agtacaatac actcgttgtc
    20581 ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa tatacctacc
    20641 aactcttgac acgctaccct aatcctcaga aaaggcttga ggcaggattt gataagctga
    20701 tagaaattaa gcgattgacc gcttctaatt caagggcttt ttgccgtgct ctaaaatcat
    20761 cgccaaatca tcaaattgaa ataagaaata gtttagataa aactattgac ttttcttata
    20821 gtttgtcttt ctcttaataa cgttgatatg attgacctct ggatcttccg tcccttggag
    20881 ggagcaacca cgttccttgg cgaattggat atagtcgaca atttctcgtg taatgcgttc
    20941 accaggagcc aagataggaa tacctggagg gtaacacata acaaattctc cacagacctg
    21001 tccaacagaa tcatccaaag ttaaactttt tctttctgaa tagaaggctt cttgcggaga
    21061 cagcactaac tcgggctgaa tatattctcc tgctatcaaa tcttttccat ctcttgaata
    21121 gagtctctta atatcagcca gagcaccaac caagcgctcg atgtcttgga tgcggtcgcc
    21181 gatggaaata taggccaaga tattgccgat atcaccaaac tcgatctgaa tgtcgtattc
    21241 gtctcgcaag aggtcataaa cctcgatacc tgttaagcca ataccctgag tgtaaactga
    21301 caacttagtt acgtcaaaat cgcaaaccga aacaccgtct attaactctt ttgagtaggc
    21361 atagtagcca ccgatagcat tgatttcacg gcgggcatac tcagatagct caatgacttc
    21421 ctcaaacgac tctttaccac gaagggccaa gttgcgacgt gaaatatcca aactagccat
    21481 caacaagtaa gaggcagatg tagactgggt caggttaatt atctgacgaa cgtattcaga
    21541 attcatctgc tccccgataa gtaaaatgga gctttgggtc aaactcccac cagacttatg
    21601 catggaaact gctgccatat cagcccctgc atccatagca ggaattggaa gtttatcagt
    21661 gaaatgcaaa tgcgctccgt gggcttcatc tactaaaacc atcatgccag cttcatgagc
    21721 catttctgtc aaccccttta ggtctgaaca gatgccgtag taagttggat tgttgattag
    21781 gatagcctta gcatctggat ggtcctttat ggcctgtgct actcggtcat tttcaagacc
    21841 taaagcgata ccaatcttag gatctacact catctcgata tagatgggaa tggcaccaca
    21901 tagaaccaac gcattgatag cagatttatg gacatttcgt ggcagaataa tcttatctcc
    21961 tgccttgcag gttgccagaa tcatagtctg caccgatgaa gttgttccac caatcattag
    22021 aaaggcatgg ctagctccaa aagcatctgc agccagctcc tctgcatcac gaataatcga
    22081 aataggatgg cctaaattat ccaagggttt catcgaattg acatcaatgc ctacacattt
    22141 ttctcctaag agttcgacaa gttctggatt tccacgtcca cgcttgtgac ctggaacatc
    22201 aaagggaaca atccttttct tgcgtaactt caccaaggcc tcataaattg gggcttggtt
    22261 ttgatctaac tctttcaaaa catactcctt tcaatatttt taggacctta tgaaaactaa
    22321 ggaactaaag gttgactcat gaaaaaagag caggttttca cctgctctgc aatcttctga
    22381 cgtttttatg tttgtttctg ttgagtatgt ctgttcccga tgtttccaaa ctctctagta
    22441 gcaaatatta cgtactttat tgatcgtttc acaagatgac gtgtgctttc accacactaa
    22501 aatttatgaa ttaggacaag cgtcctaaca tcaacttata aaagtaggct tttaacccta
    22561 tcaataatgt ggtttttcaa ccacgcttcg gcattcaacc ctgcctgtcc gtaggcattt
    22621 tttactcggg tttatatttg ctagaaaaca tcatctcatt ttctaagctt tattactata
    22681 tcatgttttt aagaacttgt aaagtatttt ttgataaaaa aacaaaatat agtagattga
    22741 aactagaata gtccacctct gcttctaaaa cattgttaga aatagatttt actgtcctga
    22801 tcgatttgtt ctgttcttgt ttcatttta
//
LOCUS       DAVDFK010000028        22574 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.28, whole genome shotgun sequence.
ACCESSION   DAVDFK010000028 DAVDFK010000000
VERSION     DAVDFK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.28"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VUR04_001427"
     CDS             join(2..341,341..1242)
                     /locus_tag="VUR04_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET5341310.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSVS
                     LDYALSNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKIEIQNIYNEHKGNYGYRRIHLELRNCGFVVNHKKVQRLMKILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASKPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKELSPVQYRTKSFG"
     gene            complement(1290..3842)
                     /locus_tag="VUR04_001428"
     CDS             complement(1290..3842)
                     /locus_tag="VUR04_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET5341311.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAIIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(3904..5526)
                     /locus_tag="VUR04_001429"
     CDS             complement(3904..5526)
                     /locus_tag="VUR04_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5341312.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            5732..6757
                     /gene="trpS"
                     /locus_tag="VUR04_001430"
     CDS             5732..6757
                     /gene="trpS"
                     /locus_tag="VUR04_001430"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET5341313.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            6909..8387
                     /gene="guaB"
                     /locus_tag="VUR04_001431"
     CDS             6909..8387
                     /gene="guaB"
                     /locus_tag="VUR04_001431"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET5341314.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVSGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(8438..9535)
                     /gene="recF"
                     /locus_tag="VUR04_001432"
     CDS             complement(8438..9535)
                     /gene="recF"
                     /locus_tag="VUR04_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET5341315.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSVQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQNGKAAVNGN"
     gene            complement(9538..9906)
                     /gene="yaaA"
                     /locus_tag="VUR04_001433"
     CDS             complement(9538..9906)
                     /gene="yaaA"
                     /locus_tag="VUR04_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET5341316.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            10065..11315
                     /locus_tag="VUR04_001434"
     CDS             10065..11315
                     /locus_tag="VUR04_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET5341317.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQIYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            11312..12595
                     /locus_tag="VUR04_001435"
     CDS             11312..12595
                     /locus_tag="VUR04_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET5341318.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRIEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            12637..13458
                     /locus_tag="VUR04_001436"
     CDS             12637..13458
                     /locus_tag="VUR04_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5341319.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            13469..14014
                     /gene="pgsA"
                     /locus_tag="VUR04_001437"
     CDS             13469..14014
                     /gene="pgsA"
                     /locus_tag="VUR04_001437"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET5341320.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            14011..14838
                     /locus_tag="VUR04_001438"
     CDS             14011..14838
                     /locus_tag="VUR04_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET5341321.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            14823..15662
                     /locus_tag="VUR04_001439"
     CDS             14823..15662
                     /locus_tag="VUR04_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET5341322.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            15655..16449
                     /locus_tag="VUR04_001440"
     CDS             15655..16449
                     /locus_tag="VUR04_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET5341323.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16508..17326
                     /gene="mreC"
                     /locus_tag="VUR04_001441"
     CDS             16508..17326
                     /gene="mreC"
                     /locus_tag="VUR04_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET5341324.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            17326..17820
                     /gene="mreD"
                     /locus_tag="VUR04_001442"
     CDS             17326..17820
                     /gene="mreD"
                     /locus_tag="VUR04_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET5341325.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            17914..19092
                     /locus_tag="VUR04_001443"
     CDS             17914..19092
                     /locus_tag="VUR04_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5341326.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            19316..20095
                     /gene="rpsB"
                     /locus_tag="VUR04_001444"
     CDS             19316..20095
                     /gene="rpsB"
                     /locus_tag="VUR04_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET5341327.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            20174..21214
                     /locus_tag="VUR04_001445"
     CDS             20174..21214
                     /locus_tag="VUR04_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET5341328.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            21461..21784
                     /gene="tnpB"
                     /locus_tag="VUR04_001446"
                     /pseudo
     CDS             21461..21784
                     /gene="tnpB"
                     /locus_tag="VUR04_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(21939..22225)
                     /locus_tag="VUR04_001447"
                     /pseudo
     CDS             complement(21939..22225)
                     /locus_tag="VUR04_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            22216..>22574
                     /locus_tag="VUR04_001448"
     CDS             22216..>22574
                     /locus_tag="VUR04_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341329.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHV"
BASE COUNT         7207 a         3651 c         4660 g         7056 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtgtt agtcttgatt atgccctctc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa tcgaaattca gaacatttat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaattgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgaaaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgaag ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggcttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccca acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tctatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttgaaatcgg agatgtttta tggttatgag aagagcttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 gaacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg tctaactttt
     1261 tggggtcagt acattaactg gtcgattttt tatgccttag atgactttcg tctgtgatta
     1321 tagattccaa atagtaagag agaagtaaag gaacagattg ctccagtaat aaaaccattg
     1381 ggaatgaagg aaagtgtaat agttcctttc cccttgggaa tgtcaacttt cataaatcca
     1441 gtttgagctt gtttaatttc tattttctta ccatcttggt aggcagacca acctttgtca
     1501 taaggaatgg tgaagaaaat agatgtatct tgttggacat catatgtagc aaaaaccttg
     1561 tttttagaag ttgatactgt gacaggttgt tctttaattt tttgaattgc ctcggtgaaa
     1621 gttttggtat ctaaacgata gaaggtagga gattcaaatg atacttgtga atttccaggg
     1681 aaactaacat tgatattgaa agtttttttc tctttagtat atcctagatt aaagaaggag
     1741 aagacattat cagttgtaaa agtctttttt tcaccattta caaggatgtc aaccttcttt
     1801 tgtttatcgt tagaaaagtg aaggtttatg aaagagagat aaacttggct gttttctgga
     1861 acttcaattt gatactggat tgctgcatct tcatttgaag aacttgtgac actaatcaaa
     1921 tcattagtat tttctatttt ttctgttttt tcataaggta ttggagaaaa ataatcaaaa
     1981 ttgacgttag caagttgatt taaaaatgag gcctgattat ccaaggtatg ttcattgaac
     2041 ttgacatcat tgtaaacaga ttgactagca actgcaatcg gaagagagta ttgattttca
     2101 tatagggtaa gattatcttt ttgatagata tctttaaagc catacttatc aataggactg
     2161 tctgagatat tgtactggat accaaataaa ctatcagcca aaatactatt atttgcatat
     2221 cggagattga gattagtccc agaggattta aaaccaagtt tatctaaagt agagcttgat
     2281 gaacgatttc gaacagatga aaattgagag attccattgt agttgaattt catactgtca
     2341 tttcctgtct gagtttgtag tttttcagta cgagtaaatt gatttccaat atatgttgag
     2401 aaagattcca tagctgggat atctcgacta taagcacttc gagaagcaaa tccccattcc
     2461 ttagcaattc cgtccatttg agatgaagca tttaaactca tttcaaccag tataaataaa
     2521 gagattagaa tggcaaatag attcacagat ataaactttt tgataattgc aaggagtaaa
     2581 agagaataga caaccaaaaa ttcaagagta agcagaatat tcaaatctgt taaaaaagaa
     2641 taatgcgatt ttagatagat ggtagctaaa aatcctgcta ctacaagaaa aagcgaaact
     2701 aaaaaattcc agactttaag ttctttcaga cgctttaaga cttctgctgc tgtgtaaatt
     2761 aacaaggtag agaaaatcca agcatagcga tgtaaaaaca tgtttggagt atgcatgcct
     2821 tgccaaaata agtcaagagc ttctatgtaa aagcttgcaa ttagaaatgc aaagaatatt
     2881 acatatatga gtttcacgtg aaacttaata gatttcagcg taaaaaataa aatggtcaaa
     2941 ataaagggaa atagtccaac aaaaatcatt gggatggccc catactttgt tgtgtcaaag
     3001 gaaccaatga attgcttagc aaagagatca agataccagc tactttcagt ttgaaacttt
     3061 gtaacttcag tcaatttttc cccatgtgtc tgtaaatcaa atagagtggg aagagtcata
     3121 atcaaactag ccataccagc taaaaaggag ataactatga aatcaagaac agatgatttt
     3181 cgagtcttaa agtcccacga aatttgacag agataccaga aaataagaaa caatactgtc
     3241 atatatccaa aataataatt ttgaataaat aagattgaca gacttgtaaa gtacaatagg
     3301 agtttctttt cagttatcag tagatgtaaa ccagttataa ttaaaggaat caagataaaa
     3361 acatctagcc aggtttttat ctctaattga ctgacagtga aactcatcag agcataggaa
     3421 gtagataagg ctagttttaa agtctgaggg atagattgaa acaatttatt caaactaaaa
     3481 aaggttgaca gaccaatcaa tccaaatttt aagagagtgg tcagatagac agcatctggc
     3541 atattcgtta gatcaaaaaa gtaaactaga ggcgcgagaa aactacccaa gtaataacta
     3601 gatagggcat agaagtttag ccctagacca cttgtaaagg tgtaaaacag actactattt
     3661 ccatgtagga tatttcgtaa ggctacatca aaaataacgt attgatgaaa gccatctcct
     3721 aatagaggag agttgtcgct attccagtag ataccttgag atagatatac tccagacata
     3781 atcactacag gaatgatgaa agaaataaaa taggttcgat atgtttttaa aaatgatttc
     3841 atgttacctc gtagaatgat agaaaactca gttggttaac ccaactgagt tttgaagttt
     3901 tatttagtct ttccaaagtt ctttaacttt tgcttgtact tctgcatttt ctaggaattc
     3961 atcgtaggtt tcatcgatac ggtcaatgac gccattttta gataagacaa tgatatggtt
     4021 agccaaagtt tgaataaact cgtggtcatg gctggcaaag atgattgatt ctttaaagtt
     4081 tttcaatcca tcattcaagc ttgagataga ttccaagtcc aagtgatttg ttggatcatc
     4141 aagtacaagg acatttgatt ttaagagcat gagttttgaa agcatgacac gaactttttc
     4201 tccccctgac aagacattta caggtttgtt aacttcatct ccagagaaga gcatacggcc
     4261 gaggaaacca cgtaggaaag tattgtcatc ttcttcttta cttgcgaatt gacgcaacca
     4321 gtcaagaatt gattctcctc ctgcaaaatc agctgagtta tcttttggta ggtaagattg
     4381 actagttgta actccccact tgacagttcc ttcatagtca atatctccca tgattgcacg
     4441 aattaatgca gtcgtttgaa tatcattttg tccaataagt gctgtcttat catctggacg
     4501 caagatgaaa ctaatattat ccaagatagt ttcaccatca atctttacag ttagattttc
     4561 tactgtcaag agatcattac caatctcacg ttccgcttta aagttgataa atggatattt
     4621 acgactagat ggtacaatct cttctagctc aatcttatca agcattttct tacgtgatgt
     4681 tgcctgcctt gacttagaag cattggcaga gaaacgagca acgaattctt gcaattgttt
     4741 aattttttct tctgctttag cattacggtc tgctagcaat ttagcagcaa gctcagaaga
     4801 ttccttccag aagtcgtagt ttccgacata gagtttgatt tttccaaagt caaggtcggc
     4861 catgtgagta caaactttgt ttaagaagtg acggtcgtgg gatactacga taactgtgtt
     4921 atcaaagtca atcaagaagt cttctaacca agtaatcgat tggatatcca aaccgttagt
     4981 aggctcgtcc aagagaagaa catctggttt accaaaaagt gctttggcga ggagaacctt
     5041 tactttttca ccgttggcca attcgctcat gttttggtag tgtaattctt ctggaatgtt
     5101 taggttttga agtagttgag aggcttcact ctctgcttcc caacctccaa gttcggcaaa
     5161 ttctccttcg agttcggcag cacgaacccc gtcctcgtct gagaaatctt ccttcatgta
     5221 gatagcatct ttctctttca tgatgctata aagtttttca tttcccatga taacgacatc
     5281 aatggcacgt tcatcttcgt agtcaaagtg attttgacga agaacagaga gacgttcatc
     5341 tggaccaaga gagatgtgac cagtagtagg ttcgatatct ccagctaaaa tttttaaaaa
     5401 ggttgatttt ccggcaccat tagcaccgat taatccgtaa gtatttcctt ctgtaaattt
     5461 gatattgaca tcatcaaaaa gtttgcgatc actaaaacgt agtgaaacat cagatactgt
     5521 aagcaatatt tttctcctat atgtgtaata tatttattct actagaaaat acagaaatat
     5581 tcaaattttt atttgtcaat tttgtgtaaa ttatatttac agtatccttt acacaaatct
     5641 gtaaaaagca aggctgattt attttgataa attacggtta tttcattaaa aaaatgctat
     5701 aattgaaagg actatatcga aggagaacaa aatgactaaa cccattattt taacaggaga
     5761 ccgtccaaca ggaaaattgc atattggaca ttatgttgga agtctcaaaa atcgagtatt
     5821 attacaggaa gaggataagt atgatatgtt tgtgttcttg gctgaccaac aagctttgac
     5881 agatcatgcc aaagatcctc aaaccattgt agagtctatc ggaaatgtgg ctttggatta
     5941 tcttgcagtt ggattggatc caaataagtc aactattttt attcaaagcc agattccaga
     6001 gttggctgag ttgtctatgt attatatgaa tctagtttcg ttagcacgtt tggagcgaaa
     6061 tccaacagtc aagacagaga tttctcagaa aggatttgga gaaagcattc cgacaggatt
     6121 cttggtctat ccaatcgctc aagcagctga tatcacagct ttcaaggcta attatgttcc
     6181 tgttgggaca gatcagaaac caatgattga gcaaactcgt gaaattgttc gttcttttaa
     6241 caatgcatat aactgtgatg tcttggtaga gccggaaggt atttatccag aaaatgagag
     6301 agcagggcgt ttgcctggtt tagatggaaa tgctaaaatg tctaaatcac taaataatgg
     6361 tatttattta gctgatgatg cggatacttt gcgtaaaaaa gtaatgagta tgtatacaga
     6421 tccagatcat atccgcgttg aggatccagg taagattgag ggaaatatgg ttttccatta
     6481 tctagatgtt tttggtcgtc cagaagatgc tcaagaaatt gctgatatga aagaacgtta
     6541 tcaacgaggt ggtcttggtg atgtgaagac caagcgttat ctacttgaaa tattagaacg
     6601 tgaactgggt cctattcgtg agcgccgtat tgaatttgct aaggatatgg gagaagttta
     6661 taatatgatt caaaaaggta gtgaaagagc gcgtgaagtt gcgggtcaaa ccctatctga
     6721 ggtaaaaggg gcaatgggac ttcattactt taactaagtt tattttacaa gaaactatca
     6781 tttctatctc gaagaaaaga tagtttttta tttacccctg taacatttga caaattttta
     6841 tagaatggta tgatagatac aatataaaaa gagtcaagct caaaaagaaa gaaaagagga
     6901 aacttcgaat gtctaattgg gacactaaat ttttgaaaaa aggttttacc tttgatgatg
     6961 tattgcttat tccagctgaa agtcatgtgt tgcctaacga tgcagattta acaactaaat
     7021 tggcagataa tttgacttta aatatcccaa ttattaccgc tgccatggac acagttacag
     7081 agagtcaaat ggccattgct attgctcgtg caggtggtct cggagttatc cataaaaaca
     7141 tgtcaattgc tcaacaagca gacgaggttc gtaaggtaaa acgttctgaa aatggagtta
     7201 ttattgatcc gttcttcttg acgcctgaac atacaattgc tgaagcagat gagcttatgg
     7261 gtcgttaccg catcagtggt gttccagttg ttgaaacact tgaaaatcgt aaattggttg
     7321 gtattttgac aaaccgagat cttcgtttta tttcagatta taatcaacca atttcaaacc
     7381 atatgactag tgaaaatctt gttactgcac ctgtgggtac ggatcttgca acggctgaga
     7441 gtattcttca agagcatcgt attgaaaaac ttccgttggt tgatgaagaa ggcagtcttt
     7501 ctggtttgat cactatcaaa gatattgaaa aagttattga gtttccaaat gcggctaaag
     7561 atgagtttgg tcgtcttcta gtttcaggtg cagtaggtgt tacttcagat acatttgaac
     7621 gtgcagaggc tctttttgag gcaggagcgg atgcgattgt tattgatact gcacatggtc
     7681 attctgcagg tgtcttgcgt aaaattgccg agattcgtgc tcatttccca gatcggactt
     7741 tgattgctgg aaatattgct actgctgaag gtgcacgtgc cctttatgaa gcgggtgtag
     7801 acgttgttaa ggttggtatt ggaccaggtt ctatctgtac tactcgtgtg attgctggtg
     7861 ttggtgttcc gcaagtaaca gctatctacg atgctgcagc tgttgcgcgc gaatatggta
     7921 aaacgattat tgctgacggt gggatcaagt attctggaga tattgtaaaa gcacttgctg
     7981 caggtggaaa tgctgttatg cttggatcta tgtttgctgg aactgatgaa gctccaggcg
     8041 aaactgaaat cttccaagga cgtaaattca agacttaccg tggtatggga tcaattgctg
     8101 ctatgaagaa aggttcaagc gaccgttatt tccaaggttc tgtcaatgaa gcaaacaagc
     8161 tcgttccaga aggaattgaa ggtcgtgttg cttataaagg agcggcagct gatattgttt
     8221 tccaaatgat tggtggtatt cgctctggta tgggttactg tggtgcagct aaccttaaag
     8281 aactacacga taatgctcaa tttattgaaa tgtctggtgc tggtttgaaa gaaagccatc
     8341 ctcatgatgt gcaaattact aatgaggcac caaattattc tatgtaaaaa acaatgaaaa
     8401 gaactccagt gaaaacagga gttcttttac aatgttgtca atttccattt acagcagctt
     8461 taccattctg aatagtgaag atacttagat tttctggcag attttgaaga tggtctaagc
     8521 ttgttgttgt gataaaggtt tggattgatt gagaaatcgt ttctaataat tttaactgtc
     8581 tagtgttgtc aagttcactc atcacatcgt caagcagtaa tatcggagat tctgtggtaa
     8641 tgctttccat taattcgatt tctgctaatt ttatcgagag gacgagacta cgatgttgac
     8701 cttggcttcc gaaactagca tccatcccat ttatataaaa agaaatgtca tctcgatgag
     8761 gaccgacacc agtattcttt ttaaataaat ctctggatct acttttttct aaagcaattt
     8821 tgaaagattc ggataagttt tgtttgtcag ttatattgac agaagattga taggatattg
     8881 acaactcttc gatctgatta gagagttcaa aatgtttctt acgcccaaat gattctagtt
     8941 tttttatgaa atctaagcgg tgattcatta cacgacatcc ataatcaact agctgatcat
     9001 ctaacacaga aaggaatgtt tcatctattt tttgaactga ttttagataa gtgtttcttt
     9061 gctttaggat gtggttataa ttggttaagt cagataaata gattggctta atttgcccaa
     9121 gctccatatc aatgaatttt cgtcgaatcg aaggtgctcc tttaattagt tgtaaatctt
     9181 caggagcaaa taagacaaca ttcatgtgtc ctacataatc tgaaaggcgt gcctgtttta
     9241 agtgattaac ttttgttaca cggccttttt gtgttagttc gatttctagg ggaatggatc
     9301 cagttttttt ctgaacgaga cctgaaagat gaagttgttc ctcatcaaaa tgaatgagat
     9361 ttttatctgt tcgagttcga tgactacgcg ttaaggctaa aaaatagata gcctctaaca
     9421 tgtttgtttt tccttgtgca ttacgtccca aaaagacatt caatttagga ttaaagtcta
     9481 ttttcgtttc tttgtaatta cgaaaagtct tgagagatag atgttgtagc cacatgatta
     9541 tctaccaggg aatcgtggag cttgttggct tttaggtgat gaagcaggtt tcgatttgtc
     9601 ttttttaact cccttattca tctttttgac aagtttagcg atccgttctt tttcaacttt
     9661 atcagcttgg tattcatctt gttcttcaga agtaggttgt gtcaacaaga tgtcaatgtt
     9721 catgtcaggg atgtcaactt tatcgccaat acgaagtttt tttccacgac gactctctaa
     9781 ttccctatta aagtaaacag aatgttcaga gagaaatgat ttaatagctc ctccgctatg
     9841 tgtaattcca agttctttga gtagtgcttg gagggtaata aattcttcaa ataatttgta
     9901 ttccataatt cacctcaatc tttggtatta taccatattt tcctaaaaat agtgagagag
     9961 acagcgagaa atgtaagcga tttttatttc aaaagtgtta cagggaacaa gaaaatttca
    10021 ggttttcgtg atataataga agtctgtata taaggaggta aatcatggag ttagtgcatg
    10081 gaatttcaac acattttatc caatcaaaaa agtttaaaac aaacaaaatt accgtgcgtt
    10141 ttaccgctcc attatccctt gatacgattg caggtcacat gttgagtgca agtatgctag
    10201 agactgctaa tcagatatac cccacttctc aagatttgag gagacacttg gccagtctat
    10261 acggtacaga tatgtcaacc aattgtttca gaagagggca aagccacatt atagaattga
    10321 catttaccta tgttcgtgat gagtttttaa gtaggaaaaa cgtgctaacc tctcagattt
    10381 tggaacttgt aaaagaaact cttttttcac ccgtagtagt tgataatggg tttgatccgg
    10441 ccttatttga aattgagaaa aaacaattgc tagcaagttt agcagctgat atggatgatt
    10501 ctttttattt tgcacataaa gaattggata aattgttttt tcatgatgaa cgtcttcaat
    10561 tggaatatag tgatttacga aatcgtattt tagctgaaac tccacaaagt tcttattctt
    10621 gtttccaaga atttttagcc aatgatcgaa tagatttctt tttcctaggt gattttaatg
    10681 aggttgaaat tcaaaatgta ttagaatcat ttggctttaa aggtcgaaaa ggagatgtga
    10741 aggttcagta ttgtcaacct tattctaata tccttcagga aggtatggtt cggaaaaatg
    10801 tgggacaatc cattttggaa ttaggttatc attaccgttc taaatatggt gatgagcaac
    10861 atttacccat gattgtaatg aatggtttac ttggtggatt tgctcactct aagctcttta
    10921 caaatgtccg tgaaaatgct ggattagctt ataccatttc aagtgagctt gatttattta
    10981 gtggattctt gaggatgtat gctggtatca atcgagaaaa tcgtaaccag gctcgtaaaa
    11041 tgatgaataa tcaactgctt gatttaaaaa aaggttattt tacagagttt gagttaaatc
    11101 agaccaagga aatgattcgt tggtcgttgt tactttctca agataatcaa tcttcattga
    11161 ttgaacgtgc ttatcaaaat gccttatttg gaaaatcttc agcagacttt aaaagttgga
    11221 ttgcaaagct tgaacaaatt gacaaagatg ctatttgtag agtagctaat aatgtgaaac
    11281 tacaagcgat ttactttatg gaaggaatag aatgacaaag gttgtttttg aagaaaaata
    11341 ctatccagct gtaaaagaaa tggtttatcg aactcgtttg gccaacggat tgacagttgc
    11401 tcttttgcct aaaaaggaat ttaaagaggt ttacgggagt gtcactgtac agtttggttc
    11461 ggtagatacg tttgtcacag aagttgacgg agatgtaaaa caatatcctg gaggaattgc
    11521 tcattttctt gaacataaat tatttgagag agaagattct agtgatttga tgtcggcttt
    11581 tacgagtcta ggtgcagata gtaatgcctt tacaagcttt acaaaaacaa actatctttt
    11641 ttcagcaacg gattattttt tagaaaattt agatttactt gatgaattgg taacatcagc
    11701 acactttact gaagcttcca ttctgacaga gcaggatatt attcagcaag aacgagaaat
    11761 gtaccaagat gatccagatt cgtgtttatt cttttcaact ttagcgaatt tgtatcctgg
    11821 tacaccttta gcaactgata tagttggaag tgaggagtcc atttcccaaa tcaatctaac
    11881 taatttgcaa gaaaatttta caaagtttta caaacctgta aacatgtctc tgtttttagt
    11941 tggtaatttt gatgtggagc gagtacagga ctattttgaa agcaaagaac tgaaagattc
    12001 agattttcag gaagtagcaa gagaaaagtt gtttttacag cctgtaaagc caacagatag
    12061 tatgagaata gaagtatctt ctcccaaact agcgattgga gttagaggta agcgagaagt
    12121 ttctgaagcg gattgctatc gacatcatat tttattaaaa ttattgtttg caatgatgtt
    12181 tggttggact tcggatcgtt ttcaaaaatg ttatgaatca ggtaaaattg atgcatcctt
    12241 atctctggaa gttgaagtaa caagtcgctt tcattttgtc atgttgacaa tggatacgaa
    12301 agagccagtt gctttgtctc atcaatttag gaaggctatt cgtaatttta caaaggattt
    12361 agatattaca gaggaacatt tagatattat caaaagagag atgtttggcg aatttttcag
    12421 tagcatgaac tctcttgaat ttattgcaac gcaatatgat gcttttgaaa atggtgagac
    12481 aatttttgat ttgccgaaaa ttttacagga aattacttta gaggatgtcc ttgatgctgg
    12541 acatcattta atagatgatg gtgacatagt tgattttaca atattcccat cgtagtaacc
    12601 tattataata gacactagaa agaagggatg acaagtatga gaaaaaaaac aattggagag
    12661 gttttacgat tagctagaat caatcaggga ttgagtttag atgaattgca gaaaaagaca
    12721 gaaatccagt tagatatgtt ggaagcaatg gaagcagacg atttcgatca acttccaagt
    12781 cctttttaca cgcgttcttt cttgaaaaaa tatgcatggg ctgttgagtt agatgaccaa
    12841 attgttttgg atgcttatga ttctgggagt atgattactt atgaggaagt agatgttgat
    12901 gaagatgagt tgacaggtcg tagacgttca agtaagaaaa agaagaaaaa aacatcattt
    12961 ttacctttat tttattttat cctttttgct ttatcgattt taatttttgt gacttattat
    13021 gtttggaact atattcaaac tcaaccagag gagccttctc tttctaatta cagtgtggtt
    13081 caatcaacaa gttcaactag ctctgttccc cactcctcaa gtagtagttc ttctagtata
    13141 gaatcagcta taagtgtatc aggcgaagga aatcatgtag aaatcgctta taagacaagt
    13201 aaggaaacag ttaaattgca attggcagtt tcagatgtta caagttgggt cagtgtttca
    13261 gaaagcgaac ttgagggcgg tgtaacctta tcgccaaaga agaaaagtgc agaagcaaca
    13321 gttgcaacta aaagtcctgt aacaattacg ttaggtgttg taaaaggtgt tgatttgaca
    13381 gtagataatc agactgttga tttatcgaaa ttaacagctc agactggaca aatcactgta
    13441 acctttacta aaaattaagg aaaaacgaat gaaaaaagaa caaattccca atctcttaac
    13501 aataggtcga attctcttta tacctatttt tatctttatt ttaacgatag gaaattcgat
    13561 agagagtcat atagttgcag ctattatctt tgctgttgcc agtattaccg actatttaga
    13621 tggatattta gctcgtaaat ggaatgtggt cagtaatttt ggtaaatttg cagatcctat
    13681 ggcggataag ttactagtta tgtcggcttt tattatgttg attgagttag gtatggctcc
    13741 ggcttggatt gttgcagtga ttatctgtcg tgagttagct gtgacaggtt taaggctttt
    13801 attggttgaa actggtggaa caattttagc agcagcaatg cctggaaaaa ttaaaacttt
    13861 tagtcagatg tttgctatta ttttcttgct attacattgg actttgcttg gtcaagttct
    13921 actttatgta gccttatttt tcactatcta ctctggctat gactatttca agggtagtgc
    13981 ctatgtattt aaagggacat ttggttcgaa atgaaatcaa taattgatgt aaaaaatctt
    14041 tcttttcgct ataaagaaaa tcagaactac tacgatgtga aggatattac gtttcacgtg
    14101 aaacgtggag aatggctttc gattgtaggg cataatggta gtggtaaatc aacgacggtt
    14161 cgattaattg atggcttact ggaagcagaa tccggagaga ttgtaattga tggccaacgt
    14221 ttgactgagg aaaatgtttg gaatatacgt cgtcaaatcg gtatggtttt tcaaaatcca
    14281 gacaatcaat ttgttggagc gactgttgaa gatgatgttg cttttggttt ggaaaatcag
    14341 ggactttctc gtcaagaaat gaaaaagaga gtggaagaag ctctggcttt agttggcatg
    14401 ttggacttta aaaagagaga gccagcgcgt ctatcaggtg gccaaaagca acgtgtggcc
    14461 attgcaggtg ttgtagccct aagaccagct attttaatct tagatgaagc aacgagtatg
    14521 ttggatcctg aggggcgtag agaacttatt gggacagtaa aaggaattcg aaaagactat
    14581 gatatgacgg tcatttctat tacccatgat ttggaagaag tcgccatgag tgatcgcgta
    14641 ttggtcatga aaaaagggga aattgaatca actagtagtc caagggagct tttctctcga
    14701 aatgatttag atcaaattgg attagacgat ccttttgcta atcaattaaa aaaatctttg
    14761 agccagaatg gctatgattt acctgaaaat tatttgacag aaagtgagct agaggataag
    14821 ctatgggaat tgctctagaa aatgtgaatt ttacatatca agaaggtact cccttagctt
    14881 cagcagcttt gtcggatgtt tctttgacga ttgaagatgg ctcttataca gctttaattg
    14941 ggcacacagg tagtggtaaa tcaactattt tacaactctt aaatggttta ttggtgccaa
    15001 gtcaagggag tgtgagggtt tttgatacct taatcacctc gacttctaaa aataaagata
    15061 ttcgtcaaat tagaaaacag gttggcttgg tatttcagtt tgctgaaaat cagatttttg
    15121 aagaaacggt tttgaaggac gttgcttttg gaccgcaaaa ttttggagtt tctgaagaag
    15181 atgctgtgaa gactgcgcgt gagaaactgg ctctggttgg aattgatgaa tcactttttg
    15241 atcgtagtcc gtttgagctg tcagggggac aaatgagacg tgttgccatt gcaggcatac
    15301 ttgccatgga gccagctata ttagtcttag atgagccaac agctggtcta gatcctctag
    15361 ggagaaaaga gttgatgacc ctgttcaaaa aactccacca gtcagggatg accatcgtct
    15421 tggtaacgca tttgatggat gatgttgctg aatatgcaaa tcaagtctat gtaatggaaa
    15481 agggacgttt agtaaagggg ggcaaaccaa gtgatgtctt tcaagacgtt gtttttatgg
    15541 aagaagttca gttgggagta cctaaaatta cggccttttg taaacgattg gctgatagag
    15601 gcgtgtcatt taaacgatta ccgattaaga tagaggaatt caaggagtcg ctaaatggat
    15661 agtatgattt tggggcgtta tatcccaggg gattcgattg ttcaccgatt ggatccacgt
    15721 agcaaattgc ttgctatgat gctactgatt ttgattgtgt tttgggctaa taaccccttg
    15781 acgaatctga ttctttttat agcgacaggg atatttattg ccttgtcagg agtatctctt
    15841 tcatttttta ttcagggctt gaagtctatg tttttcttga ttgccttcac aactattttt
    15901 caactatttt tcatttctaa tgggaatgtt ttatttgagt tttcgtttgt gagaatcacg
    15961 gattatgctt tgcaacaagc tgggattatt ttttgtcgct ttgtattgat tattttcttt
    16021 tcaactttgt taaccttaac aaccatgcct ttaagtttgg catcagctgt cgaagcttta
    16081 ttagcacctt taaagcgtgt gaaagttcca gttcatgaaa ttggattgat gctgtctatg
    16141 agtttgcgtt ttgtcccaac cttgatggat gatacgactc ggattatgaa tgcacagaaa
    16201 gctcgtggag tggattttgg agaaggaagc atcgttcaaa aagtaaaggc gatgattccc
    16261 attttgattc ctctttttgc gacaagttta aaacgtgcag attccttggc tatcgctatg
    16321 gaagcgcgtg gctatcaggg tggaaaaggc agaagtcaat accgacaatt gaaatggact
    16381 ctaaaggata cgctgaccat tcttgttatt ctcgtacttg gttgttgttt atttttctta
    16441 aaatcttagt agctttcagg aattgataaa aagttactgt aacagttttt gatataaagg
    16501 taggaatatg aaccgtttta aaaaatcaaa atatgtcatt attgtttttg tcactgttct
    16561 gcttgtgtca gctctcttag cgacgactta ttcaagtaca attgtgacaa aattaggaga
    16621 tggaatctca ttggttgata gagttgtaca aaaacctttt cagtggtttg attctgtcaa
    16681 atcagatttg gctcatttga cacgaacata taatgaaaat gaaagtttga agaaacagct
    16741 ttaccaatta gaagttaaat caaatgaggt ggaaagttta aagacagaaa atgaacaact
    16801 gcgccaattg cttgatatga agtctaaatt gcaagccaca aagactttag cagcagatgt
    16861 tattatgcgt tctccggtat cttggaagca ggagttgacc ttagatgcag gtagatcaaa
    16921 aggtgcttct gagaacatgt tagctattgc aaatggtggc ttgattggga gtgtttcaaa
    16981 agtagaggag aactctacta tagtcaacct tctgacaaat acggaaaatg ctgataagat
    17041 ttctgttaaa attcaacatg gctctactac aatttatgga attattattg gctatgacaa
    17101 ggaaaatgac gttcttaaaa ttagccaatt aaatagtaat agcgatatta gtgcgggaga
    17161 taaggtgact actggtggat taggaaactt taacgttgct gatattcctg ttggtgaagt
    17221 ggttgccaca acgcatagta cagactattt gacacgagaa gtaactgtta aattgagtgc
    17281 agatactcat aatgtagatg tgatagaatt agtggggaat tcataatgag acagttgaag
    17341 cgagttggag tatttttatt gcttcctttc tttgttctaa ttgacgccca tattagccag
    17401 cttctgggct catttttccc ccatgtacat ttggctagtc attttctttt tctatttctc
    17461 ttatttgaga cgatagaagt atcagagtat ctctacctag tctattgttt tgttataggc
    17521 ttggtttatg atgtttactt tttccatcta atagggatta caactctctt atttatctta
    17581 ttgggagcct tccttcataa attgaatagt gttattttgt tgaatcgttg gacaagaatg
    17641 ctagctatga ttgtgctgac attcctgttt gaaatgggta gttatctttt ggcttttatg
    17701 gtagggttga cagtagatag catgtcgatt tttatagtct atagcttggt accgacgatg
    17761 attttaaatt ttttatggat tactgttttt caatttattt ttgaaaaata ttatctataa
    17821 gaacgacata taaatgtaac aaaggcgtaa tatttattag gccttttttt ggtatactag
    17881 tattgtcttt aaaagaagga gtatctacgt aatatgaaga aaaaaatctt agcgtcactt
    17941 ttattaagta cagtaatggt ttctcaagta gctgttttaa caactgcgca tgcagaaacg
    18001 actgatgaca aaattgctgc tcaagataat aaaattagta acttaacagc acaacaacaa
    18061 gaagcccaaa aacaagttga ccaaattcag gagcaagtat cagctattca agctgagcag
    18121 tctaacttgc aagctgaaaa tgatagatta caagcagaat ctaagaaact cgagggtgag
    18181 attacagaac tttctaaaaa cattgtttct cgtaaccaat cgttggaaaa acaagctcgt
    18241 agtgctcaaa caaatggagc cgtaactagc tatatcaata ccattgtaaa ctcaaaatca
    18301 attacagaag ctatttcacg tgttgctgca atgagtgaaa tcgtatctgc aaacaacaaa
    18361 atgttagaac aacaaaaggc agataaaaaa gctatttctg aaaaacaagt agcaaataat
    18421 gatgctatca atactgtaat tgctaatcaa caaaaattgg ctgatgatgc tcaagcattg
    18481 actacgaaac aggcagaact aaaagctgct gaattaagtc ttgctgctga gaaagcgaca
    18541 gctgaagggg aaaaagcaag tctattagag caaaaagcag cagctgaggc agaggctcgt
    18601 gcagctgcgg tagcagaagc agcttataaa gaaaaacgag ctagccaaca acaatcagta
    18661 cttgcttcag caaacactaa cttaacagct caagtgcaag cagtatctga atctgcagca
    18721 gcacctgtcc gtgcaaaagt tcgtccaaca tacagtacaa acgcttcaag ttatccaatt
    18781 ggagaatgta catggggagt aaaaacattg gcaccttggg ctggagacta ctggggtaat
    18841 ggagcacagt gggctacaag tgcagcagca gcaggtttcc gtacaggttc aacacctcaa
    18901 gttggagcaa ttgcatgttg gaatgatggt ggatatggtc acgtagcggt tgttacagct
    18961 gttgaatcaa caacacgtat ccaagtatca gaatcaaatt atgcaggtaa tcgtacaatt
    19021 ggaaatcacc gtggatggtt caatccaaca acaacttctg aaggttttgt tacatatatt
    19081 tatgcagatt aatttacaga gggactcgaa tagagccctc ttttcaggtt ttaccgtgac
    19141 aatccctatt aaaaattata tcaaaatagc ttgaaaatat tggaaaagta tggtagaatg
    19201 aaaattgtcg tgtgaacgat aatactcatt cttgatgaat tgtgaagcag ttgcccttgg
    19261 gtcgttttgc gagttgaagt caagaagagg aaaaaaacaa aaaggagaaa tactcatggc
    19321 agtaatttca atgaaacaac ttcttgaggc tggtgtacac tttggtcacc aaactcgtcg
    19381 ctggaatcct aagatggcta agtacatctt tactgaacgt aacggaatcc acgttatcga
    19441 cttgcaacaa actgtaaaat acgctgacca agcatacgac ttcatgcgtg atgcagcagc
    19501 taacgatgca gttgtattgt tcgttggtac taagaaacaa gcagctgatg cagttgctga
    19561 agaagcagta cgttcaggtc aatacttcat caaccaccgt tggttgggtg gaactcttac
    19621 aaactgggga acaatccaaa aacgtatcgc tcgtttgaaa gaaattaaac gtatggaaga
    19681 agatggaact ttcgaagttc ttcctaagaa agaagttgca cttcttaaca aacaacgtgc
    19741 gcgtcttgaa aaattcttgg gtggtatcga agatatgcct cgtatcccag atgtgatgta
    19801 cgtagttgac ccacataaag agcaaatcgc tgttaaagaa gctaaaaaat tgggaatccc
    19861 agttgtagcg atggttgaca ccaatactga tccagatgat atcgatgtaa tcatcccagc
    19921 taacgatgac gctatccgtg ctgttaaatt gatcacagct aaattggctg acgctattat
    19981 cgaaggacgt caaggtgagg atgcagtagc agttgaagca gaatttgcag cttcagaaac
    20041 tcaagcagat tcaattgaag aaatcgttga agttgtagaa ggtgacaacg cttaatttat
    20101 acaaatagta attacctagg agggcggggc ttagcccggc tctcctattt tcaaaaaata
    20161 taggagaatt aaaatggcag aaattacagc taaacttgta aaagagttgc gtgaaaaatc
    20221 tggtgccggt gttatggacg ctaaaaaagc gcttgtagaa acagacggtg acatcgaaaa
    20281 agcgattgaa ttgcttcgtg aaaaaggtat ggctaaggca gctaagaaag ctgaccgtgt
    20341 tgctgcagaa ggtttgactg gtgtttatgt taacggtaat gttgcagcag ttattgaagt
    20401 aaacgctgaa actgacttcg ttgcaaaaaa cgctcaattc gttgaattgg taaatactac
    20461 agctaaagtc attgctgaag gaaaacctgc taacaatgaa gaagctcttg ctttgataat
    20521 gccttcaggt gaaactcttg aagctgcata cgtatctgca acagcaacta tcggagagaa
    20581 aatctcattc cgtcgctttg cattgattga aaaaacagac gcacaacact ttggagcata
    20641 ccaacataac ggtggacgta tcggtgttat ttcagttgtt gaaggtggag acgaagcact
    20701 tgctaaacaa ttgtcaatgc acatcgcagc gatgaaacca acagttcttt cttacaaaga
    20761 attggatgag caattcgtta aagatgagtt ggcacaattg aatcacgtta tcgaccaaga
    20821 caacgaaagc cgtgcaatgg ttaataaacc agctcttcca cacttgaagt atggatcaaa
    20881 agctcaatta actgatgatg ttattgctca agctgaagct gacatcaaag ctgaattggc
    20941 tgcagaaggc aaaccagaaa aaatctggga caaaattatt ccaggtaaaa tggatcgctt
    21001 catgcttgat aacactaaag ttgaccaagc ttacacactt cttgcacaag tttacatcat
    21061 ggatgacagc aagacagttg aagcatacct tgaatcagtt aacgcttcgg tagttgagtt
    21121 tgctcgcttt gaagttggtg aaggtatcga gaaagctgca aacgacttcg aagctgaagt
    21181 tgcagctaca atggcagcag ccttgaataa ctaataatag aaaggaagca aattgcttcc
    21241 ttttttgtat agggcttaga tttttcctga aattgttttt tccccagtct cactcgatta
    21301 gaataattaa aacaaaaaac cctataataa gggctaagtg catttaggag actatacttc
    21361 aaattcatag taagcgcgtt cataacaagg tatctatcct aattccccaa cttccagtat
    21421 actagataaa aaataattat cggagtaaag gtattgtact atgataattc aactaagtga
    21481 tttaggtcaa gttcaccttg tttgtggcaa gacagatatg aggtagggaa tagactcatt
    21541 agcctatgta gttaaaaccc actttgaatt ggattctttc tccggtcaag tctttctctt
    21601 ttgtggtgaa cgtaaagacc gctttaaagc cctttactgg gatggtcaag gattttggct
    21661 actatataaa cgctttgaga acggaaaact gacttggcta agtacagaaa aggatgtcaa
    21721 agctctcgca cctgaacaag tagattggct tatgaagggc ttttctatca ctccaaaaat
    21781 atagtatatt gaaactagaa tagtacacct ctgcttctaa aacattgtta gaaatcgatt
    21841 tgactgtcct gatcgattta tcctgttctt atttcatttt actataaatc tatcagaaag
    21901 ttgtgatttc tattgaaatg aggactttct ttttacactc atctgctttc aaaaagcatt
    21961 ctagtccgtc tccgattaac gatggacttt atcacctcct tctccagtcc ttgtatgaca
    22021 tcttccaaag tttgaaaggc tttattctta aatccacgtt tacgaatctc tttccacact
    22081 tgttcaatgg gttcatctct ggtgtgtatg gaggaataaa ggtaaaacca atattagtcg
    22141 gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt aaaagataat
    22201 catctggata agcttgtgaa agctcctatt cctaaagccc ctttagcgca tagctttggc
    22261 tcagcttcta ttatcgctca caccatccat cagaagttta atctgaaggt acccaattat
    22321 cgccaagaag aagattgggc taggatgggt ttaccaatca cacgtaagga aatctctaat
    22381 tggcatatca agacgagtca atactatttg gagccccttt ataacctctt gcgagagaga
    22441 ctattgactc agcccttact tcatgcggat gaaacttctt atagggtgct agagagtgat
    22501 agtcagctga cttactattg gacttttttg tctgggaaag ctgagaaaca agggattacg
    22561 ctttaccatc atgt
//
LOCUS       DAVDFK010000029        22231 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.29, whole genome shotgun sequence.
ACCESSION   DAVDFK010000029 DAVDFK010000000
VERSION     DAVDFK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.29"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(88..2046)
                     /gene="ftsH"
                     /locus_tag="VUR04_001449"
     CDS             complement(88..2046)
                     /gene="ftsH"
                     /locus_tag="VUR04_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET5341330.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2062..2604)
                     /gene="hpt"
                     /locus_tag="VUR04_001450"
     CDS             complement(2062..2604)
                     /gene="hpt"
                     /locus_tag="VUR04_001450"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET5341331.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2608..3885)
                     /gene="tilS"
                     /locus_tag="VUR04_001451"
     CDS             complement(2608..3885)
                     /gene="tilS"
                     /locus_tag="VUR04_001451"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET5341332.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3882..5150)
                     /locus_tag="VUR04_001452"
     CDS             complement(3882..5150)
                     /locus_tag="VUR04_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET5341333.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5270..5638)
                     /locus_tag="VUR04_001453"
     CDS             complement(5270..5638)
                     /locus_tag="VUR04_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET5341334.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5631..5897)
                     /locus_tag="VUR04_001454"
     CDS             complement(5631..5897)
                     /locus_tag="VUR04_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET5341335.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5965..9474)
                     /gene="mfd"
                     /locus_tag="VUR04_001455"
     CDS             complement(5965..9474)
                     /gene="mfd"
                     /locus_tag="VUR04_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET5341336.1"
                     /translation="MVTLLDLLSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQGYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9475..10044)
                     /locus_tag="VUR04_001456"
     CDS             complement(9475..10044)
                     /locus_tag="VUR04_001456"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET5341337.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10115..11230)
                     /gene="ychF"
                     /locus_tag="VUR04_001457"
     CDS             complement(10115..11230)
                     /gene="ychF"
                     /locus_tag="VUR04_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET5341338.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11314..11508)
                     /locus_tag="VUR04_001458"
     CDS             complement(11314..11508)
                     /locus_tag="VUR04_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET5341339.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11573..12709)
                     /gene="dnaN"
                     /locus_tag="VUR04_001459"
     CDS             complement(11573..12709)
                     /gene="dnaN"
                     /locus_tag="VUR04_001459"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET5341340.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IEAVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12868..14229)
                     /gene="dnaA"
                     /locus_tag="VUR04_001460"
     CDS             complement(12868..14229)
                     /gene="dnaA"
                     /locus_tag="VUR04_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET5341341.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14442..15200)
                     /locus_tag="VUR04_001461"
     CDS             complement(14442..15200)
                     /locus_tag="VUR04_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET5341342.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15258..16439)
                     /locus_tag="VUR04_001462"
     CDS             complement(15258..16439)
                     /locus_tag="VUR04_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET5341343.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16622..17101
                     /gene="rlmH"
                     /locus_tag="VUR04_001463"
     CDS             16622..17101
                     /gene="rlmH"
                     /locus_tag="VUR04_001463"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET5341344.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17145..17218
                     /locus_tag="VUR04_001464"
     tRNA            17145..17218
                     /locus_tag="VUR04_001464"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17179..17181,aa:Arg,seq:tct)
     gene            17383..17508
                     /gene="comC"
                     /locus_tag="VUR04_001465"
     CDS             17383..17508
                     /gene="comC"
                     /locus_tag="VUR04_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET5341345.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17529..18854
                     /locus_tag="VUR04_001466"
     CDS             17529..18854
                     /locus_tag="VUR04_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5341346.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSSNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18851..19603
                     /locus_tag="VUR04_001467"
     CDS             18851..19603
                     /locus_tag="VUR04_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341347.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19655..19726
                     /locus_tag="VUR04_001468"
     tRNA            19655..19726
                     /locus_tag="VUR04_001468"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19688..19690,aa:Glu,seq:ttc)
     gene            19732..19805
                     /locus_tag="VUR04_001469"
     tRNA            19732..19805
                     /locus_tag="VUR04_001469"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19766..19768,aa:Asn,seq:gtt)
     gene            complement(19846..20388)
                     /locus_tag="VUR04_001470"
     CDS             complement(19846..20388)
                     /locus_tag="VUR04_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET5341348.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20567..21334
                     /locus_tag="VUR04_001471"
     CDS             20567..21334
                     /locus_tag="VUR04_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET5341349.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSYNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21419..22099
                     /locus_tag="VUR04_001472"
     CDS             21419..22099
                     /locus_tag="VUR04_001472"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET5341350.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTILVFMSMV
                     TTLTTWNSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6870 a         4099 c         3638 g         7624 t
ORIGIN      
        1 agaaaacaca tttgttccat tttctccatt ctgttccctt tagctcctaa actgcacaaa
       61 aaagagaggc tccagcctct ctcagggtta tttttcgtca ttcatttttg actttacttc
      121 atcataggat agtgcatgag attcctcttc tactgcttca ggcatctttc ctgtttcgta
      181 aagagcttta atttgtgtac tatccaatgt ttcgtatttc aataatgctt ctgcaattaa
      241 cttgtgagtt tcacgatttg actgaataat ttcagcagct ttatttcgtg cctcatttaa
      301 taatgaacga acctcttcat caatttcata agctgtttgt tctgaaattg atttttgagg
      361 actctgtgca ccaagcatag catggtttcc ttcatattgt actgggccaa gtttttcact
      421 cataccgtac tctgtaacca ttgcacgtgc catttgtgtc gcttgttcaa agtcgtttga
      481 agctcctgta gtttggacat taaagataat ttcttcagct acacgtccac ccattaagcc
      541 agccaattgc tctttcatat cttctttaga tagaagcatt tgatcctctt taggaagtgc
      601 aatcatgtat ccgcctgcac ggccgcgtgg tacaattgta accttatgga caacgcgagc
      661 attcgacaag actagaccaa caatggtatg tcctgcctca tggtaagcaa ccaattctcg
      721 ttctttttgt gaaactgtct tatctttctt agaaggtcca gcaataactc tatcttctgc
      781 ttcatcaata tctgaagcat caattatcga tttattgcga cgagcagcaa ctaaagctgc
      841 ttcattcaag acattctcta aatcagcacc aacaaagcct ggagtttgtt gagccactaa
      901 tttcaaatca acatcttctg ctaaaggctt gttcttagcg tgaactttca agattgcttc
      961 acgaccttta acatcaggac ggccaaccaa tacttttcta tcaaaacgtc ctggacgcaa
     1021 aagggcagga tcaagtacat ctgaacggtt tgtcgcagcg atgacgataa tcccttcatt
     1081 tccctcaaaa ccatccatct caatcaaaag ttggttcaag gtttgttcac gttcgtcatt
     1141 acctccgccg agaccgactc cacgttgacg tccaacagca tcaatttcat cgataaagat
     1201 gatagctggt gctgcttttt tggcatcctc aaaaagagag cgaacacgac tagctccaac
     1261 tccgacaaac atttctacaa agtcagaacc tgagatacta aagaatggaa cacctgcttc
     1321 tccagcgact gccttagcaa gcaaagtttt acctgtcccc ggaggtccct ccaaaagaac
     1381 acctgctgga atacgggctc caagttttgt gaatcgtttt ggatctttta agaactcaac
     1441 aacttcaact agttcttgtt tttcttcttc agctccagca acatctgaaa atcttacttt
     1501 aatatcttct ttatttgctg ctttagcctt actacgtcca aaactcattg gattacggcc
     1561 attgcctcct cccatatttc ccatcataga gaataggaag aagaatagaa ttccaaatgg
     1621 cacaatggat acgagtagat taatccatat accacttgaa ctttcatgct taacagttac
     1681 ttctgcttta tggtcagtag caagtttttg caattctgat acggtagtat ctgcaggaag
     1741 aatagtgctg gtaaatttct ctaccttagt aacagatggc gtgaaaaact gaatacctgt
     1801 tccttcttta cttgttttag gatttttata gacaccagaa acttcgataa cactaccatt
     1861 tggttggtaa gttaattctt ttacattacc atcggtaatt tcttgtacca actcagtata
     1921 gttgatttgc tgacttcctc ctgagttatt cccagaatag aaatactgga atcctgtcac
     1981 aaggaaaaag ataaataata accatagaaa aggattttta attaaaccat tattttgttt
     2041 tttcattaaa gattattctt tctaatttga atacacttcc tctttcaata ctccaatata
     2101 aggaagatta cgataatttt ctttgtagtc taaaccataa cctactacaa actcatttgg
     2161 gatagtaaag caggtatagt ctgcctcaat ttctacaaca cgtccttctg gtttatccaa
     2221 caaggttgca attttaacag aagctgcttc tcttgcttta aacatatctc gcaaattctt
     2281 caaagtttga cctgtatcaa tgatatcttc tacaaataga acatgtcttc ctttgatatc
     2341 ttgagtcaca tcttgtttaa tattgataac accactactt gctgttccac catggtagct
     2401 agaaaccatc atgaagtcca tttcaatatg tgtatcaata tgtttgacca attcagccat
     2461 aaaaggaata gatcctttta aaatcccaac taagattgga ttttttcctg cataatcttt
     2521 agttaattga gcacctagtt ttttagctgc ttctgtaatt tcatcgtgtg aaacgaggac
     2581 ttttttaata tcgttttcta acatttttta cctatctatt ttttctatat aaagtacagt
     2641 gttcattata tcatttttcg tttttttact caaattattg gtcgcaattc ccaaaattga
     2701 gacaatttca ccaaattgct caataataag agcagagttt ctcttttcca tagggatttt
     2761 caaatcaata aataaacgtc tgagtttttt tctatgccca ttttgaatca aaacatctcc
     2821 tgtttttcga tgacgaatgt gtatggatgt ttcacgtgaa acaggtattt gttgaattga
     2881 ttcaccttct aatggaagtc caaaggaaaa taaatatcct tgataagcta cctgattttg
     2941 atagtgtaac acaagttcat cttccttttc atcagcctgc ggactgattt tacaaatctg
     3001 aaactgttgg tactctttta tcaattcata gccattttta atcggatgac gatactggct
     3061 tttagatttt aaaatctgct gaacttcagc aaactgagct tttgtaagat tcaaatctgg
     3121 aaaacgattc agataagttt gaagtaaaac tctttgtgta gactcagagt aagaaaataa
     3181 ctgctgtaaa tcttccacat taatattgtt agataattca gctattgcca aatcataatc
     3241 taaaatttca ttgccaatgc ctaagattgc atccctaaat cgaggatttt ctttttccaa
     3301 ttctggtaag taagagtttc gaatacgatt tcgaaaataa tgattctcct gatttgatgt
     3361 atcttcaaag tgaaaaattg atggaaagtc ttttttctga aaatgcaaga agggacgaat
     3421 gatttctatc tctccgacta cttgcttctc cttaattcct gatagatagc gcaagcgagt
     3481 tcctcgaatc aagcgcatca aaatcgtttc cacctgatca tcagcatggt gggcagtgac
     3541 taaagctgtc gcacctgtct ttttcatgac ctcttgaaaa aaatcataac gaaaatttcg
     3601 tgcacgcgct tctgaaaatt ctcctgaaaa attgctgata taaataggaa gctctgcttc
     3661 agcagccaac ttccttaatt ccttttcttc ccaatctgat tcaattctct gcttatgatt
     3721 cacatgagcc agaatcaatt caatctctaa ctctttttga taagtagaca ataccttaaa
     3781 tagaaacata gaatctaatc caccagaaag agctagaacc gccttagcat gctttttgaa
     3841 atatcccttc ttgagaaaat gatttaaaaa atctggttcc ctcattttag aacctcataa
     3901 acatccttgg ctatcttaga aatcgtatca taatcagaat tcttagtgaa aatagaaaga
     3961 ataaatggag aatctgcata gacaacaccc gtatcatgct taaattcatc cgcatctcca
     4021 attttatgag ctactttaac agaaacacct ttggcaattc gctgactatc aaaatctgtt
     4081 ttagtcaaag actctagcac aaatccattt tgattataaa tagcttccat aaacttcccg
     4141 gccatcttag aagaaatcaa tttttctttt ggatcccaat catctcccat aatggcagac
     4201 atcttggatt tgaatgtggc atcagattgg tttgaaatgt aatatcccaa tagattatga
     4261 gctacattat cagattcttt tgatactttc gtaattaaat cctttaaaga atattcttta
     4321 ttatcttctt ttttaggaag actaccactt ccctctggtt tataagaacc tggaaaatca
     4381 ttgactgcag atacgtattt tacagtcgta tctaactgat aaagaccctc atttattttt
     4441 tcttgcgtat aatagagata ggagagtttc aaaacgctgg ctgcatacat cttttcatct
     4501 tgattgatac cagcttcttt tccagtagtc agttgcttaa cataaataga gaaagaatct
     4561 ttctgatatt tttcagataa catttcttga actttactca tccgattatc ttcttcagaa
     4621 gttgattctt tagctaccca tccagcctga tcaatatgta gaaattctct tccttctaca
     4681 aacatggtct tgtcgattga tacttgcgaa taagctgata aggatgattt cacttctttt
     4741 aaatcataag gactattgta cagtttaaag tcagattcta accatacttt ttttattgtt
     4801 ggagttacct ctgattgatc atataaaaat cgtttgtccg cagctataaa ttgatgattt
     4861 gatagcttaa atactggaat tccttgttta tttaagcgcc actcggttat ttgaaaactt
     4921 gttttgggag tcaatttccc agattccact actaaatctt cattcgcata aacaggaacc
     4981 tctccataaa ccatgggaga acttaatttt tctctaaaat aaataccaaa gtcagattgt
     5041 gaaaggtaat aaatttcttt cgaagtatag acgacttctt tttctgtgct aacgactttt
     5101 gaaatggtca aaaaacttgg tagcaacaaa ataattaaga atttacgcat tcttcctttc
     5161 cttttcttct tgtaaacgca ataattgatt tttatcagcc aattcttcca gcttttcatc
     5221 tgacaaactc aaaaattgct ctattacgtc taataaattt tccattttat cacctttgaa
     5281 gcaagtcagg aatcgtataa actttttccc tcgacttaga ataatagtac ttcgctcgtg
     5341 tatatttagc agcataatct tcatctttca acttggtagc aaatgctgtc tccttatcct
     5401 tttcatcact caaagtttga tactgagttt gcaagtctgc taattgctga cgtctttgga
     5461 gtaattgctg ataactctgc gctaaattaa aagttggcaa gataaataat agcataatca
     5521 aaatcaatac ccctcccata aaacgattcc gtttttgtcg ttctttcatc aggtagcgac
     5581 gacgttggta ttcattttga ataaaagaat tattcaattg tacaatattt ttagacattt
     5641 tcttctaccc gtgtttcact gataatttca tacattcctg ctgcatcttc tttttttgta
     5701 ctatctttca tctctagtac ttttacaagc agcaacttat tgccaaagcg aatttcaact
     5761 tggtcattaa ctttcaagtc cgttgaactt ttggccaaga ttccattaac cttgattcta
     5821 cctttatctg ctacttcctt tgcgactgta cgacgcttga taattcgcga tacttttaaa
     5881 tatttatcta atctcatcct tattacctca atttattatt gtaccatttt tatctatttt
     5941 tatctatttt atagaagaaa aatatcaaat ggaattttct tccttaaact cttttatctc
     6001 taataaactt tctccaaaaa tcagcagacc ttctaaaatt tcataatctt tcttattttg
     6061 gacatcaaat acaagctcca ttaatccctt attctcagcg atgcctgctt ttaagttcgt
     6121 tacggataaa gctttaaaat aatcttgagc taaaaacagt cgttgagtga ctttttcaaa
     6181 ttgaattgta attttattat cttttctttc cacacgttga acaaagacct tgtccaagta
     6241 tgatttgacc aaaccaatct ctaaaagata ggctactaca tctgggtatt ctccaaaacg
     6301 gtctatcaac tcctcttgta actcttcata attgacacgg ttgtcaattt gacgaatttt
     6361 cttgtaaatt tcaatcttat gtcgttgatc agaaatataa gtatcaggaa gataggcatc
     6421 aatttgcaaa atcaactcag cattcccttt ggttcttgtg ttagcgttag cattaccgtt
     6481 tcgtttagca atagcttcct ctaataactg cgaatacaat tcaaaaccaa cagaatcaat
     6541 gaaaccagac tgggattttc ctaaaagatt tcctgctcca cgaatcgaaa gatctcgcat
     6601 tgcaatctta aagccagagc ccaattctgt aaatccttta atcgcttcta atctcttttc
     6661 agagacttca ctgattgatt tttctggacg atacatgaga taagcataag caatacgatt
     6721 actacgaccg actcttcctc ttaactgata taaggttgac aagcccatat ggtccgcatt
     6781 ttcaataaat aaagtattag catttggaat gtccacccct gtctcaataa tagtagtagt
     6841 caccaagata tcgtattgtc cctcaataaa gtctaataga gtattttcca actggacttc
     6901 actcattcga ccatgaacat atccaatcga agcctctgga atcaactcct gtaattctga
     6961 aaccttctga acaattgtgt caactttgtt gtaaagatag taaccttgac ctccacgctc
     7021 catttcacgc aagacagcat cacgaatgac actatcattc ttttccaaaa cataggtctg
     7081 aacagggtag cgattagtcg gcggagtttc aataacagac aaatctctga ttcccagcat
     7141 agacatatgg agggtacgag ggattggcgt agcggtcaag gttaggacat ccacttgttt
     7201 cttcagttct ttcaaagttt ccttatgctt gacaccaaat cgctgttcct catcaataat
     7261 catcaagccc aaatcagcaa acacaacatc ttttgacaaa acacgatgtg ttccaatcaa
     7321 aatatcgact tgaccgtttt tcaatttttc aagtgttgca gtctgctctt ttttacttct
     7381 aaagcgactc aacacatcaa cattaactgc aaaattttgg aatcgttcct taaaattcgt
     7441 atagtgctgt tgcgctaaaa ccgtcgtcgg aactagaatg acaacctgtt tgtgatcatt
     7501 gactgcttta aaggctgcac gcatagcaac ttcagtcttt ccaaaaccaa catccccaac
     7561 taaaagtcga tccattggct gagaagcctg catatccctc ttgatttcct caatactacg
     7621 aagttgatca tccgtttcaa cataagggaa agcatcatca aaggcatctt gatcatcatc
     7681 atcagctgag aaagcaaaac ccttcaactg actacgttca gagtagagtt tgattaaatc
     7741 atcagctata tcctctacct ggttcttaac cttttgcttg gcctttttaa aatgaccgtc
     7801 atttaattta ttgagttttg gagctttacc atcacttgaa atatatttgg acagtagatg
     7861 aatctgttcc acggggatag aaatttgatc accattttgg tattggacac tgacataatc
     7921 gcgatgaatt cccttgattt caatggtttc aattcctaga tattgaccaa tcccatggat
     7981 atgatggaca acatagtccc ctttttcaag ttcattgtaa tcttttaatc tctctgcatt
     8041 tgaaacatgt tgtcttcgaa aacgacgctt taatttcttt tgaaaaatct catgttcagt
     8101 tatcaataaa atcttttcat ctacaaaatg aaaaccatgt ctgagattac cctctattaa
     8161 gtttacagat tctttacaga tacttgtctt atctctagaa tccaatttaa tctgatattc
     8221 ctctaacata tcctccaatg ttttacttcc cattgaattg ctagactgca gaataatggt
     8281 gtaatccatt tttttatatc gttcaatttc ttcttttaga aaagaaaact gattgaaaaa
     8341 ttcctgcata ggatattgat tgaattgata aattttgtca aatttgagat ttcctaaacc
     8401 cttttgaaga ttagagaaaa aggtcactgg actttgtttt ttatagattt gttcaatatc
     8461 agaaaaatac tgcatatcag aaaatgcttt actattctgt aattcttctg taaagtactg
     8521 cgctaagtct ctttcaaaga cttcatactg attcatcaat ttttgataat catcaaagaa
     8581 tattggagta tctttttcaa tataatcaaa gacagtccat gtcttatcat agcacaaaga
     8641 taaaaacttc cgagagtctg catgactttg tttttggtga aaacttgaaa gaatttcttc
     8701 taggtatgat ttcaaaatag gtgataaagt ttttgaaatt tgtttttcta aagctgactg
     8761 tcctcgttga taatcctttt ctctcaaaag catatcacta gctggaaaga tagtgagttc
     8821 tgtcttattt tctttcgata attgtgtttc tacttcaaat gacctgatac catcaatttc
     8881 atcaccaaaa aactcaattc gacaaggttc taactgggat atttcaaaaa tatctaaaat
     8941 atctcctcga agactaaatt cgccctgagt ttgtacttga gtaacttttc gatagccatt
     9001 ttcttttaac tgatggataa acgcgtgttg atcatattct tcaccaactg agatttttac
     9061 aatactatct ttgaatgcat tgggagacgg taaaatcaat cgacttgctg cgatattaca
     9121 aactaaaatc cctttcttag atgaatcagt caaaaaacgc aaggcttcaa cccgtgaaat
     9181 aattttttcc tgtgaagaca tcaaaaactc caccatagga gcatcatcta ccaaaaatgg
     9241 atagacgagt tcctcaccca agatagagat aagatcacta acaagtcctt ctgcttctcc
     9301 ataagttgac gtcaataaca caatcctatc ttctttttct aaactgcttg caattgcaag
     9361 agccttagta gatgttgata aaccaagtat tagttgtctt ttcttatctg ttaaattttg
     9421 atgccatttt ttaatctgat cattttctga gagtaaatct aataaggtca ccatttatcc
     9481 gttatacctc tgcattgttt tctcaaaatt tttctcttgt aaatagtagt ttacagaatc
     9541 gtcaactttg tcaacagact gtaaaatacc gatataatca tccctgtcaa acttactcaa
     9601 aacatgatga acaactgaca taccattttt aggtcttcca attccaatct taacacggtt
     9661 aaagacctga gttcctatat gttgaataat agacttgata ccattatgac cacctgctga
     9721 gccttttgct cttaaacgaa ttttcccaac ttccatgtca agatcatcgt aaatgataag
     9781 taaatcgtca atatccaaac catagtaagt taataaagca tgaactgctt ttccactttc
     9841 attcataaag gtcgttggtt taaccagata aattttttct ccatttagga aaaaggatgc
     9901 taggtcagct tgaaatatct tatcgtgtgt aaaagtgaca ttctgtttct tcgctagttg
     9961 atcaatcaac ataaaaccaa cattgtgttt tgtttcaaaa tatttatccc ctggatttcc
    10021 caaacctaca agtaatttgg tcatttattt ttcctttcaa aagccaaaag ggttggaatt
    10081 tttttccaac ctaattgaca ccatttatta atttttagac attaaagcgg aattccatga
    10141 tatcgccatc ttgaacgata tattcttttc cttcttcacg caagcgtcca gcttctttta
    10201 cggccttttc agatccgtat ttcactagat cttcatatga catggttact gcacgaataa
    10261 agcctttttc aaagtctgag tggataatac cagctgcttg aggagccttc ataccacgtt
    10321 tgaaagtcca agcgcgaact tctttttcac cagctgtgaa gtaagttccc aatccaagca
    10381 agtggtaagc tgcacgcgtc aacttatcta cacctgattc tgtcaaacca atggcttcaa
    10441 gaaactcttt tttatcttca tcatccaatt cagaaatttc ttcctcagca cgcgcagaaa
    10501 taacgactac ttcagcattt tctgtcgctg caaattcacg aatttgtttg acatagtcga
    10561 tagagtcagg ttctgaaacc acatcctcgt ccacattagc tacataaaga actggtttag
    10621 tcgtcaaaag gaaaagacct ttgacaacct tttgttcctc atctgtaaat tcaatggtac
    10681 gagctgattt cccgtcttct aggactggtt taatcttttg aagaacattg aattctgcta
    10741 ctgattcttt atctttttgc gtacgtgcca tcttttctac acgcgcatat cgtttgttca
    10801 ctgattctaa gtcagcaaga attaattcca gattaattgt atcaatatct gcaagcggat
    10861 ctacaaaggc gtcttcacgt ccttgctcgc gcattacatt ttcatcatca aaagcacgaa
    10921 ctacgtgaac aatcgcatct acttcacgaa tattggccaa gaatttattc cccagccctt
    10981 ctccttttga agctcctttt acaatccctg caatatctgt aaattcaaat gttgtgggaa
    11041 ctgtcttttt aggagttatc atttcagtta gtttttgtag gcgttcatct ggaacttcca
    11101 ccattccaac atttggatca atagtcgcaa atgggtagtt tgctgcctct gctcctgctt
    11161 ttgtaattgc attaaatagt gttgatttac caacgtttgg caaaccaacg atacctgctg
    11221 tcaaagccat atttctcatt ctccgttttc atttcaatcc ctaatattat aacacaaaaa
    11281 gggataaagt gctaaccctc taactaaggg ttctcagtca ataattttat tcatttttcg
    11341 ctcaaaatca tatcgcccca tcatgacaac atgctcacaa ttactgcatt ttattttgat
    11401 atctgctcct acacgtgtaa tttcccaacg attagccttt ttaccagtcg acttgattgt
    11461 acaagcgtgt gattttttca tctcaacaaa atttccaact tgatacatac tactctcctt
    11521 ttctttttcg attatatcat aaaagaggcg agccaggctc aacctctttc acttaatttg
    11581 tacgaactgg tgtaatgagc tgcatgaagt cttcgtcagt atctgctggc acaagagtaa
    11641 atggacgaac agctgagata aagctaatgg tcaccttttc gctatttaaa gctttaagag
    11701 aatcaatcaa gtaagttggg ttgaaactaa tggtcaaatc ttcaccagta acctgatcag
    11761 tatcgatttc ttcgtttact ttaccaactt ctggagagtg aacatgggcg ctaacaaccc
    11821 catccttaat ttcaagtttc acagtaccat tttgagtcgc acttgataaa agacgggcac
    11881 gctccattga ctggcgtaag tttaccacat taaaagtaat agtagtgtta aagtctgttg
    11941 gaatcaagcg atctgtatca ggatagtttc cttctaggag acgagtatag aagctaatat
    12001 tttcgcttct aaagaggatt tggttattgg caaagaaaat ctctacagct tcgatatcat
    12061 ctgtaaatac cgctgaaaat tcgcgtagag aacggctagg aattacgaca tcaaaatcat
    12121 cactattttt ttcaagagtc aattttttct ggcttaggcg atgagagtct gttgcaactg
    12181 tttttaactc tttgtgttga ctcaatacga agtggacacc tgttaaaatc ggacgactct
    12241 cttgtgtact tgcagcaaag gctgtttcat taataatttt cttgagtaat tttgtttcaa
    12301 gtattaaagg agtgcttgct gaaatttctt ggattcgtgg atattgttcg ctatcttttc
    12361 cttttagggt aatttctgat ttgccactgg ttaaaacaat ttgattttgt tcaatttctt
    12421 taaaatcaag agttacatca ggtaaactag atactacatt gataaagaaa gaagcttcaa
    12481 gaaggatcga acctaaagaa gtaattaaca aaccagcatc ttcatttttt tgagaaataa
    12541 aattttcaat tgaaatttga ccatttgaac caattaaagt aataccttca ttggtcacgt
    12601 caatttttac tgttgataaa ataggaatgg catttttaga actaatagct ctcttagtag
    12661 tatttaatgc ttgtagaaat aaatttttat taattgaaaa atgaatcatg gattctcctt
    12721 tatttatttt tagtattaga aagataatag taataataga gtctgtgaaa tctgtggaaa
    12781 acagccttta aacaagtcat atcaagtttt ttagcttgtt taaaaaatgt ggataaaaaa
    12841 gataaaaaac taaaagttat ccacaaatta tttgattttc tttttgattg attcaatttc
    12901 taaacgtaaa ttatcgtctt gatcaatcaa agattttatt ttggcatggg catgaatgac
    12961 tgtggtatga tcttttcccc caaattcctt cccaattttt ggaagactat tatctgttag
    13021 ttctctagat aaatacatgg ctacttgacg ggccaaaaca atattttgaa ggcgtctact
    13081 tcccttcatt tctttgatac taacaccata aaagttacca acttcagttt ggattttatc
    13141 aattgggatg acgagcattt ggctaacatc ttgtttgcgg gctctaatgg cttctgcagc
    13201 aatatcaata gtgatgtcct tgattttttt tactctggca attaaagtga tgtcgttgat
    13261 ggctccctca agatctcgaa catttgaatc aaattgccca gctaggtatt ctagagtatc
    13321 actttggaaa ttgtagccta aatgttccgt tttactttgt aaaatggcaa tacgtgtttc
    13381 aaagtcaggg ggtgtgatag tttgtgtcaa tccccaacta aaacgcgtga caagcctctc
    13441 ctcgagccct tctagatgtt ttggactacg atcactcgtt aggacaatct gtttttgctt
    13501 gtcatgaagg gcgttaaagg tattgaaaaa ttcttcctga gttgcaactt tttttccgct
    13561 gagtgactga atatcatcga ttaacaaaag atcaagacta cgataggtct ttttaaactt
    13621 ttccatttcc ccaagtctta ggtgatcaag aaagtcatta ataaagcttt cggcagggat
    13681 atatttaaca cgcgcattag gaatattttt tagaatttca tttccaatag cgtttaataa
    13741 gtgagtctta ccaaggcctg gtcctccata gataaaaaga gggttatagg tcagagccaa
    13801 atcttcagag acagctaaag cggctgatac agcccaaaca tttccatccc cttgaataaa
    13861 gttatcaaag gtatactttt cttttaatcc cgtatctgaa taaggaatag atactaactt
    13921 tggactatag ttataaagag ttaaatttgt agcttcttca acttgtgagc tagtcgtatc
    13981 ttgaggtttg gtgaaaatat agtggggagt tatttcagcg tcataaattt caaaaccagc
    14041 tactacaata atatctttta gttgtttttc ccagaccatt tccatttcag agcgaggtag
    14101 aaatatagtg gcaacatttt cctctacctt gatgagttca gcttgaatag catagaaatc
    14161 atacatggat cgagtcagtc tttcttgtgc aaattctaat atacgattcc aaaattgttt
    14221 ttctttcaat cctttctcct cctttactat ttaaaagttt aatactagag atattttacc
    14281 atagatagca agaattttcc acaagctgtg aaaaataatc cacaatgtta ccaaacttta
    14341 tccacaggtt ggggataaaa gaagaaatta ttgatttatt aagcttttta tcgaaaaaca
    14401 tagtggataa ccttgtgaga taaaaaaata aaagaacagc cttatttcag gctgttgata
    14461 attctactat attcttcttg atttgaaaaa gaaataatga tttttccact gtctttttta
    14521 gatagtttaa tttctacatc taatccgagt agttttctta actgtttttc ttcattttgt
    14581 atgaaatgat tagttttttg ctgtttcttt tgttttttct ctgtcagaag agcttctaat
    14641 ttccttacag aaatatcttc ttctataatc cgttgaaaga aatagtcttg ttgttcctta
    14701 tttaacccaa ctagggaacg cgcatgggct tgtgatagtt tgccattttc tacttctgaa
    14761 agaatctgtt ctggcaagga aagtaaacga atggagttgc tgatatatgg acgagacttg
    14821 cccatcttat ctgcaatttc agcatgggtg aatcctttct ctacgagaga ttcataggcg
    14881 cgtgcttctt ctattgggtt taaattttct ctctgtaaat tttcaataat ggactggacc
    14941 atcatctctt ggtctgaaat ctgtttaaca acagctggga tagaccgtag accagctaaa
    15001 agtgaagccc gatagcgtct ctctcctgca aggatttcat aaccaataac aggagattga
    15061 cgaacaataa tcggttgaat gaccccattt tctttgatag actgtgctag ttcatctagt
    15121 ttttctctat caaattcttt tcggggttga tagggatttt tttgtatatc tgtgatagaa
    15181 atcatttcaa atttttccat gattctacac taacacatct tttctcttat gtaaagcttt
    15241 ctttacatag atgtcaatca agattctaaa tcacctgaac tcttgttaag tttgatagag
    15301 gtagtttctt ctttcccgtt acgatagtag gttatcttaa tggtgtctcc gatagaatgg
    15361 ttgtaaagag cactttgtaa gtctgttgat gaagcaatct ctttgtcatc tacttttgta
    15421 attacatcgt atttttcaag gtgaccattg gcaggcatat tactttgtac cgaacgaaca
    15481 actacaccag atgtaacatt acttggaata ttgagtcttc tgatgtcgct tgtactcaca
    15541 ttagataaat taaccatctg gattcccaaa gctggacgcg tcacttttcc gtttttttct
    15601 aactgttcaa taatattgat agcatcattt gcaggaattg cgaaaccaag accttctaca
    15661 gatgttcctc catttgtagc aattttactt gaggtaattc cgataacctg cccttgaata
    15721 ttgatcagtg ggccgccaga gttacctggg ttaatagcag tatcagtttg gatggctttt
    15781 gtagaaatag cttgtccatc ttccgatctt aaggatacat ttctattgag actggatacg
    15841 ataccttgag tgacagtatt tgcatattca gaacctaacg ggctaccgat ggcaatagca
    15901 gtttctccta cagttaactt actagaatca ccaaactcag ctactgttgt cactttttct
    15961 gaagagattt tgacgacagc aatatcagag aaagtgtcag ctccgacaat ttctccaggt
    16021 actttagtcc catctgacaa tctaatatct actttgctgg cgccatttat aacgtgattg
    16081 ttggtgacga tgtaagcttc tttatcattc tttttataaa taactccaga tccttcacta
    16141 gagattcgct gagaatctgt gtcagtatca tcattgccaa atacgctatt ttgtctgttt
    16201 gccgaataag taataacaga aacaacagca tcttttactt tgttaacagc ctgtgttgtt
    16261 gaattttcgt tcttataggc agtttgtgta atagtactat tgttgttaga gttgtttaca
    16321 ctactttttt gagttagttg agttattgaa aaactaccca aggctccact aaaaaagcta
    16381 atgacgataa cgactaataa ttgaaaccat tttttgtaaa atgtttttag atgtttcata
    16441 tttgcctcca tatgtttgaa ttactgaaag tataaactga ctagcttaat tataacttaa
    16501 acacaaaagt tttacacaaa ctgtggataa ctcttttgaa actgtgattt tcttaattga
    16561 aatctatttt ttattttgtg aataagatgt gaaaaaatag agaatatgtt agaatagagt
    16621 catgaaaatt aaagttgtaa cagttgggaa actgaaagaa aagtatttaa aagatggtat
    16681 cgcagagtat tcaaaacgaa tttctagatt tgctaagttt gaaatgattg agttatcaga
    16741 tgaaaaaaca ccagataagg ctagtgaatc agaaaatcaa aagattttag aaatagaagg
    16801 tcagagaatt ttatcaaaaa ttgctgaccg tgatttcgtt attgtgttag ccattgaagg
    16861 gaaaactttc ttctcagaag aatttagtaa gcagttagaa gaaacttcta taaaaggatt
    16921 ttctactctt acttttatta ttgggggaag tttaggattg tcatcatctg taaaaaatag
    16981 agccaatctt tctgtcagtt ttggtcgcct aaccttaccc catcagttaa tgagactagt
    17041 tcttgttgaa caaatctatc gcgcttttac gattcagcag ggattcccct accataaata
    17101 gaaaattgac ttttaattga atttttggta gaataattgt attaggtctc atagctcagc
    17161 tggatagagc attcgccttc taagcgaacg gtcgcaggtt cgaatcctgc tgggatcaat
    17221 ataatagcaa agctgggaat tttcccggct tttttcttaa aaaagtacac tttgggagaa
    17281 aaaaatgaca gttgagagaa ttttatctaa aacgaaattc cattttgtat aatggttttt
    17341 gtaagttagc ttacaagaaa aaacatttta ggagatttta ttatgaaaaa cacagttaaa
    17401 ttggaacagt ttgtagcttt gaaggaaaaa gacttacaaa agattaaagg tggggagatg
    17461 aggttgtcaa aattcttccg tgattttatt ttacaaagaa aaaagtaatg aaataagggg
    17521 aaagagtaat ggatttattt ggatttggga cggttattgt tcatttttta attattagtc
    17581 acagttacca ttttatttgt aaaggtcaaa taaatagaaa agaattattc gtttttggtg
    17641 cttatacatt actaacagaa atagtatttg attttccctt atatattcta tatttagatg
    17701 ggttagggat tgaaagattt ttatttcctt tgggattata ttcctatttt cgatggatga
    17761 aacagtatga gagggataga ggactattcc taagtttact actatctctt ttatatgaga
    17821 gcactcataa ctttctgtcc gtaactttct cctctataac aggagataat tttgttttac
    17881 aatatcattt cccattcttt ttcgttgtga cggtgttaac ctattttgtt acattaaaaa
    17941 tcatttacta tttccatttg gaactagcct attttgacga ggactacctt tatcctttct
    18001 tgaaaaaagt attttttgct ttactattgc tacatattgt atctttcgtt tcagatatgg
    18061 taagtacgat taaacatttg aatagttttg gaagtatttt gtcatctatt gtctttatct
    18121 ctctcctttt gaccttcttt gcaatgaatt ctcataaagt tcaaatggag aaagagattg
    18181 ctttgaagca gaagaaattt gaacagaaac atttacagaa ttacacagat gaaattgttg
    18241 gtctgtataa tgaaatccgt ggttttcgac atgattatgc tggaatgctt gtcagcatgc
    18301 agatggcaat tgacagtagt aatttacagg aaattgacag aatttacaat gaagttttag
    18361 tcaaagcaaa tcataaattg cgttcagata agtacactta ctttgatttg aacaacatag
    18421 aagactcagc tttacgaagt ttggttgctc agtcaattgt ctatgctcga aataatggtg
    18481 tagagtttac actggaagta aaagatacga ttaccaagct tccaattgaa ctattggatt
    18541 tggttcgtat catgagcgtt ttattgaata atgctgtcga aggatcggct gatagctata
    18601 aaaagcagat ggaagtagca gttattaaga tggaaactga aacagttatt gtgattcaga
    18661 attcatgtaa aatgacgatg actccttcag gagatctatt tgccttagga ttctccacta
    18721 agggaagaaa tcgcggagtc ggattaaata atgtgaaaga actactagat aagtacaaca
    18781 atattatttt agaaacagag atggaaggca gtacatttag acaaatcatt agatttaaga
    18841 gggaatttga atgaaagttt taattttaga agatgttatt gaacatcaag tgagactaga
    18901 gagaatattg gatgaaattt cgaaagaatc gaatattcca atatcataca agacaacggg
    18961 aaaagtccgt gaatttgaag aatacattga aaatgatgaa gtaaatcagc tttatttcct
    19021 agatatcgat attcatggaa ttgagaaaaa gggatttgaa gtggctcagc tcattcgtca
    19081 ttacaatcct tacgctatta tcgtctttat cactagtcga tcagagtttg cgactctaac
    19141 ctataaatac caggtatcag ccctagattt tgttgataag gatatcaatg atgagatgtt
    19201 taagaagaga attgagcaaa atatcttcta cacgaagagt atgttacttg aaaatgaaga
    19261 tgttgtagat tatttcgact acaattacaa gggaaatgat ttaaaaattc cttaccatga
    19321 tattttgtat attgaaacaa caggggtctc tcataaattg cgcattattg gtaagaattt
    19381 tgcaaaagag ttttatggta ccatgacaga tattcaggaa aaggacaaac atactcagcg
    19441 attttattct cctcacaagt catttttggt aaatataggc aatatcagag aaattgatcg
    19501 aaaaaactta gaaattgttt tctatgaaga ccatcgttgt cctatttcaa gattaaaaat
    19561 tagaaaatta aaagatattt tagagaaaaa atctcaaaag tgattgacaa ttagcaagaa
    19621 attgatataa tggttatatc tgctacagat agaaggtccg ttggtcaagg ggttaagaca
    19681 ccgccttttc acggcggtaa cacgggttcg aatcccgtac ggactatttt atccgccata
    19741 gctcagttgg tagtagcgca tgactgttaa tcatgatgtc gtaggttcga gtcctactgg
    19801 cggagtatag ataaaaggga acacagctgt gttcctcttt ttgtatcaat ttgtatcacc
    19861 aagcattttc ataaggaagt ctgttatttc ttgagaactt tctttttttc catgtgcaat
    19921 ccaagtttgg cagacaccaa aaagtgcatg agttagatag atgctactat attctaattc
    19981 ggtggtattt agattcagtt gcataaatcg cttttgtaaa tctgtactaa gcatgatatg
    20041 aagtttattt cgtaagaaat tttggatttc tttagtccca ttttcagaaa gaagggcagc
    20101 cagaagtggt tctgactcta gatattcaaa aacttctaaa atagcgtctc ttttgtgatg
    20161 agcatgtttt tgaaaaatat attcaaatgt atggaatagc ttgctttgat agtgctcaat
    20221 catatcatac ttatccttat agtgagtata gaagctggaa cgactaattc cggctttttc
    20281 tactaatttg acagtagaaa ttttatcaaa tggctgttcc atcagtaatt gtaccatagc
    20341 attttcaata gttcgctttg tttttaagcg tttgttactt tcttgcatat ttcctccttg
    20401 taaacaaatt agactatatg tctaaaaata gattttttat cttgtaattt agatttttta
    20461 atgtataatc tattatatca aaattttaga caatatgttt aaaaaaggag aaactatgtt
    20521 taaagaatgg aaagcaattt aaaaaaaacc aacctttatt attgtcatga tcgggatttc
    20581 tcttattcca gctctataca atatcatatt tttgtcatca atgtgggatc catatgggca
    20641 attgtctgac ttacctgtgg cagttgtaaa taatgataaa gaggcttcct ataatggtaa
    20701 tactatggca ataggaaaag acatggtgtc caatttaaaa gaaaataaaa ccttggattt
    20761 tcattttgta gatgaagagg aaggaaagaa gggattggaa gatggcgatt actatatggt
    20821 agtgacttta ccaagtgatt tatctgaaaa aacaactaca ttatccaata ttcaatcgac
    20881 agcagcttat caatcattga caagtgagca acaaactgag ataagtgatt ctgtatctca
    20941 aaattcaact gatagtattc aatcggctca gtcaattgta gctttagtac aagatttaca
    21001 gggaagttta gaaaacttac aaaatcaatc ttataatctt tcgactttaa aaaatcaatc
    21061 taatcaagta tcacctatta cttctacttc tttgatagga ttgtcaagtg gattaacaga
    21121 gatacaagga gatgttacta gcaaattagt tcctgccagt cagtcgattg catcaggtgt
    21181 aaacgcatat actacaggtg ttgataaagt ttctcagggc gcaagtcaac taagtgaaaa
    21241 aaatgccacc ttgacaggta gtttggataa actagtttca ggctcaaaca ccttgacaca
    21301 aaaatcttct agattgacag caggagttgg ttaattacaa tcaggatctg ggcaattagc
    21361 agacaaatcc agtcagttac tttcaggtgc ttctccatta gagaatagag ctaataaatt
    21421 ggcagatgga tctgggaaac tagcagaagg tggaacaaag ttaacttctg gattggaaga
    21481 tttacagaca ggacttgctt ctttaggaca aggactaggt aatgctagtg atcaactcaa
    21541 atcagtatca acagaatcta aaaatgcaga gattttgtca aatccactca atctttcaaa
    21601 aacagacaat gatcaagttc ctgtaaatgg aatcgcaata gctccttata tgatatcagt
    21661 tgctcttttt gttgcagcaa tatcaacaaa tatgatattt gcgaaattgc cttcaggacg
    21721 tcatccagag agccgttggg cttggttgaa atctcgagct gaaataaatg gtattatagc
    21781 tgttttggca ggaattttgg tatatggagg agttcagctt attggtttaa ctgctaatca
    21841 tgagatgaga atatttattc tcatcatcct aacaatttta gtattcatgt ctatggtgac
    21901 cactttaaca acgtggaata gccgtatagg agcttttttc tcacttattt tgcttttact
    21961 acagttagca tcaagtgcag gtacttatcc acttgctttg acaaatgatt tctttagatc
    22021 tattaatccc tggttaccaa tgagctattc agtttcggga ttacgacaaa caatctctat
    22081 caacaagtca ttttcctagc tgtcatacta gctctattta ctggtttagg tatgctagcc
    22141 tatcaacata agaaaatgga agaagattaa aaaaaatcga ccgattaatg aactgccccc
    22201 caaaagttag acagaaaaaa tctaactttt g
//
LOCUS       DAVDFK010000030        22092 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.30, whole genome shotgun sequence.
ACCESSION   DAVDFK010000030 DAVDFK010000000
VERSION     DAVDFK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22092
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.30"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(40..888)
                     /locus_tag="VUR04_001473"
     CDS             complement(40..888)
                     /locus_tag="VUR04_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5341351.1"
                     /translation="MNTNLKPKLQRFASATSFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1040..1318
                     /locus_tag="VUR04_001474"
     CDS             1040..1318
                     /locus_tag="VUR04_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341352.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1320..3383
                     /locus_tag="VUR04_001475"
     CDS             1320..3383
                     /locus_tag="VUR04_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET5341353.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3461..4717)
                     /locus_tag="VUR04_001476"
     CDS             complement(3461..4717)
                     /locus_tag="VUR04_001476"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET5341354.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEESYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            4859..7324
                     /locus_tag="VUR04_001477"
     CDS             4859..7324
                     /locus_tag="VUR04_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET5341355.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            7389..8300
                     /locus_tag="VUR04_001478"
     CDS             7389..8300
                     /locus_tag="VUR04_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET5341356.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            8530..9228
                     /gene="dapD"
                     /locus_tag="VUR04_001479"
     CDS             8530..9228
                     /gene="dapD"
                     /locus_tag="VUR04_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET5341357.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            9296..10426
                     /locus_tag="VUR04_001480"
     CDS             9296..10426
                     /locus_tag="VUR04_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET5341358.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQNMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10438..10977
                     /locus_tag="VUR04_001481"
     CDS             10438..10977
                     /locus_tag="VUR04_001481"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET5341359.1"
                     /translation="MKSELRKQVLQGMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKRVLTPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDVSKIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            10961..11638
                     /locus_tag="VUR04_001482"
     CDS             10961..11638
                     /locus_tag="VUR04_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET5341360.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(11705..12604)
                     /gene="galU"
                     /locus_tag="VUR04_001483"
     CDS             complement(11705..12604)
                     /gene="galU"
                     /locus_tag="VUR04_001483"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET5341361.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(12626..13642)
                     /locus_tag="VUR04_001484"
     CDS             complement(12626..13642)
                     /locus_tag="VUR04_001484"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET5341362.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWKAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            13854..14235
                     /locus_tag="VUR04_001485"
                     /pseudo
     CDS             13854..14235
                     /locus_tag="VUR04_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(14409..14834)
                     /locus_tag="VUR04_001486"
     CDS             complement(14409..14834)
                     /locus_tag="VUR04_001486"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341363.1"
                     /translation="MTNLSSVDSEDLFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(14902..15552)
                     /gene="phoU"
                     /locus_tag="VUR04_001487"
     CDS             complement(14902..15552)
                     /gene="phoU"
                     /locus_tag="VUR04_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET5341364.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQTSKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(15567..16319)
                     /gene="pstB"
                     /locus_tag="VUR04_001488"
     CDS             complement(15567..16319)
                     /gene="pstB"
                     /locus_tag="VUR04_001488"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5341365.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16321..17136)
                     /gene="pstA"
                     /locus_tag="VUR04_001489"
     CDS             complement(16321..17136)
                     /gene="pstA"
                     /locus_tag="VUR04_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET5341366.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17129..17992)
                     /gene="pstC"
                     /locus_tag="VUR04_001490"
     CDS             complement(17129..17992)
                     /gene="pstC"
                     /locus_tag="VUR04_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET5341367.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18110..18985)
                     /locus_tag="VUR04_001491"
     CDS             complement(18110..18985)
                     /locus_tag="VUR04_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET5341368.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19152..20483)
                     /locus_tag="VUR04_001492"
     CDS             complement(19152..20483)
                     /locus_tag="VUR04_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET5341369.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(20484..21191)
                     /locus_tag="VUR04_001493"
     CDS             complement(20484..21191)
                     /locus_tag="VUR04_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341370.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21275..21577)
                     /locus_tag="VUR04_001494"
     CDS             complement(21275..21577)
                     /locus_tag="VUR04_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET5341371.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEVVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(21564..21785)
                     /locus_tag="VUR04_001495"
     CDS             complement(21564..21785)
                     /locus_tag="VUR04_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET5341372.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            21747..22092
                     /locus_tag="VUR04_001496"
                     /pseudo
     CDS             21747..22092
                     /locus_tag="VUR04_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6420 a         4235 c         4798 g         6639 t
ORIGIN      
        1 tacgtacggc aaggcgacgt tgacgtggtt tgaagagtat tagaatgctt tcccaaccag
       61 aatctctgct tcgatggtaa tctctgtcag ttggctccag tcaatcttgc tctggtcaac
      121 gtgaaagagg agaggagtca tactgagtag ggcttggagt tgttctgctg tgatagtctt
      181 agtcagagag gcagtttgac tagataggat ggtaaagtgt tcctggaaat gctccttgat
      241 atcttggtta gaatactcct tgtttgtcag ctggtcctgt actctttgac ggatttcttt
      301 gaggtgattt tcagttggga taacctttat caagataccg tctttggata aaacgcgacg
      361 aaattctcca tagttggcag gtgagaagat atcaagcaga atatccatgt tagcgtcttt
      421 tataggaagt cgtgccaagt cgccaacgaa ccaattgact gcccagttgg gttcactttt
      481 agcagcgatt tggactgaat ctttggagat gtcaaaggca tagaaagttt tttcagagtg
      541 actttcttgt agtttgcgag aatagaatcc ttcaccacaa ccgatatcca aaattgttgt
      601 ggtagttttt gagcttgcaa gcaagtcaga tacagcatct aagatagctt ggtaaaagcc
      661 ggcttctagg atttgttgac ggttttgaaa attttccttg tcatagttag cagattgctt
      721 gatttgaggt gctagattga catagccaaa tttcgccaag tcaaaagaat gacggttgca
      781 gcacttgaaa ttagtctcta acagagtcag attttcttga cagataggac aggcaaagga
      841 agtcgcagaa gcaaaacgct gaagtttggg cttgagattt gtattcatag tttaagtgta
      901 tcaaaagagg caaatgaaag caactttagg aataagtaga tgggagattc agtagaaata
      961 aaactaattc tccaatttat agaatgaaat tgcttttata tctaaattgc tatataataa
     1021 tgataaggag gaaataagta tgttaaaaga agtattaacc gttgcaaaag ttgcgaaaaa
     1081 atcttcatta tttttgggtg gtgtcgcatt tggtaccctt ggtttgaaaa tcttagcaag
     1141 taaggaagct aaaaaaggtt attctaaagc tttggctaag gcttacaagt tgaaagacga
     1201 gctagatgca tctgtttctg ttgtgaagca acatggagac gatgtcttgc aagatgccaa
     1261 atatttgtac gagcaagaga aaaaagaaga gcaattagat agccttatag gtgaataata
     1321 tgtcttttaa agtgctacat agaggatacc aacatatccg actatcatct tctttttcac
     1381 ttaccttgga tattcaagac tatcttcgtt ccttggcgag agatgaaaag gggattgagt
     1441 ctatccagtt ttacatggat caacagcact ttactctacg cataaaagaa ggcttttctg
     1501 tattagataa tgcagaagcc tttttaaaaa gaattgataa agggaaagtt tctgagttga
     1561 tgactcttcc cattcgtaga gaagagagtg cttattctat tgtttcaggt gcagcggtta
     1621 agcgtgtact ttttcgtagt tttgtgccgt atcctattcg ctatatatgg acttgttatc
     1681 aggctttggg ttatattaga gaagcctatc aaacactagc gcgtaaggaa ctaacgatgg
     1741 aagtcttgga ctgttcggct attttattgt ctttgtttat gaaccaatcc aagacagcta
     1801 gcaatatcat gtttatgctt gatttgggga atcatttaga tcagtggtcc ttgaaaaaaa
     1861 ctgcaacaga tttagaacag agtcttcttg caaaagagag cgatgtattc ctagtacagg
     1921 gcgatacggt tgttagtatc aagagttccg atgttcaaat aggagatgtc ttgatcttat
     1981 ctcaaggaaa tgaaattctg tttgatggac aagtagtttc aggtttaggt atggtcaacg
     2041 aaagttcctt gacaggagag agttttccag ttgaaaaaag agagtctgat ttggtttgtg
     2101 caaatacagt attagaaact ggagagttac gcattcgtgt aacagataat cagatgaaca
     2161 gccgtatttt acagctgatt aagttgatga agaaatctga agaaaacaag aaaacgaaac
     2221 aacgctattt catcaagatg gcggataaag tcgttaaata taatttcttg ggggctgggc
     2281 tgacttacct attgacaggt tctttttcta aggctatttc tttcctattg gtcgatttct
     2341 cctgcgcttt gaaaatctct actcctgtag cttatttgac agttatcaag gaagggttga
     2401 accgtgaaat ggtgattaag gatggagatg ttctggagaa atatctggaa gttgatactt
     2461 tcttgtttga taagacagga acaatcacaa ctagttatcc tatagttgaa aaggtgttac
     2521 cttttggaga ctatagtgag gaagatattc tcagaatcag tgcctgtctt gaggaacaca
     2581 tttatcatcc tattgctaat gccatcgtca agcaagctga gatagaggga attgaacatg
     2641 aggaaatgca tgggaaactc caatatatcg caagcaaggg gatcaaatct catatagatg
     2701 gccaaccagt tcttattggg aattatgtct tgatgcagga tgagcagatt catatcagtt
     2761 cagaacaaaa tgctttaatt gaagagtaca agagtcacta caatctctta ttcttggctt
     2821 atcaaaatga attgattgga atgttctgca ttcatactcc tttgagaaaa gaagcaaaaa
     2881 cagccttgga taaacttaag gcacagggga aaaaattgat tctggcaaca ggagacacct
     2941 tgattaggac agaggaatta gtcaaagatt tgccctttga tcaggtctat acagacttga
     3001 aacctgatgg gaaatttgag ttagtagaga aactgcagaa agcaggtcac actattttga
     3061 tggttggaga tggattgaat gactcagcgg ctttaactct atcagatatc ggtgtggtga
     3121 tgaatgagag tgcagatatt tctaagcaga tgagtgatat cttattgtta gataatcgtt
     3181 tggatttctt ccaagagttg gattcgttat catcatcttt gcaaacactc atcaagaaaa
     3241 atattcaaga taccgttgtc gtaaatagta gtttgattgg ctttggctta tttaattggc
     3301 tcagtccttc aaatctctct atcttacata atctaacaac cttgcgcatt gtcctgcgta
     3361 gcctgtctat taaaaataga tagatgagag ttattaacag caaaaaggag ttacctttct
     3421 cgaggttaac tcctttgttt atagataaat gttgaatagt ttagtaagtc aatacaaagt
     3481 attttttctt cccacgacgg ataacagtca gttcattttc taacttatca gcgtcactca
     3541 agacatagtc aaggtcttgg atgcggtcgc cgtttacgta gatggctccg ttttggacgt
     3601 cttcacgggc ttggcgtttt gagttaacta taccagatga gacgagcagt tccacgatat
     3661 tgttgtgttc gtctgcctgt acttggtagt ttggcacacc acgaagtcct tgtttgagct
     3721 ctttgacaga aaggtttttg atgtttcctg caaagagttg ctcagtgatg ttaagtgctt
     3781 ctttgtagga ttcttctccg tgaacaagtg taacaacttc acgagccaag actttttgag
     3841 ccaagcgttc gtgtggcgct gcttcaaatt gtttgcgaat atcttcaatc tcatcaagtg
     3901 acaagaaagt aaagattttc aagaagcgaa cagcgtcagc gtccatcacg ttcatccaga
     3961 attggtacat ttcgtatgga gaagtctttt cgggattgag ccagacggca tttccttctg
     4021 atttaccaaa tttcttacca gttgcatcag tgattagtgg aacagtgata acgtgaccag
     4081 tcttgtccgc cttacgacga agcaattcgg taccagctgt catatttccc cactggtcag
     4141 aaccaccgat ttgaagagtg acattatggt cttggttaag gacgaagaag tcataccctt
     4201 gcatgatttg gtaagcgaac tcagtgtaag aaattcctgt ttcgatccgt tttttaacag
     4261 attccttact catcatgtag ttgaccgtga agtattttcc aatatcacgg aggaagtcaa
     4321 tgaagctgat gctgccaaac cagtcgtagt tgttgaccat gacagccttg ttttcgccat
     4381 tttcaaagtc aagaaaacga gaaagttgtc cttggataga cttgacccag ccatctactg
     4441 tgtcttttgt ttggagacta cgttcagcat ctttgaagga cggatctccg atgagacctg
     4501 tagcaccgcc aacgagcgca taaggtttgt gacctgctag ttgcaagcga cgacttgtca
     4561 agattgcgac aaggtggcct aggtgaaggc tgtcagcagt tggatcgtag ccagtataat
     4621 aagaaacttg accttcttct agggctttac gcaaagcttc ttcatcagtc gtttgaaata
     4681 tcaaaccacg ctcttttagc tcatcaaaaa tgtgcatgtg tcttttctcc tttttaaaat
     4741 tattgtttct acctattgta tcacaaactt gggcaatagc ctagcagaat agggaagaaa
     4801 gtggctattt tattgaaaat ttcccttttg tggtataata gataaagtga ggaaatccat
     4861 gcaaaatcaa ttaaatgaat taaaacgaaa aatgctggaa tttttccagc aaaaacaaaa
     4921 aaataaaaaa tcagctagac ctggcaagaa aggttcaagt accaaaaaat ctaaaacctt
     4981 agataagtca gccattttcc cagctatttt actgagtata aaagccttat ttaacttact
     5041 ctttgtactc ggttttctag gaggaatgtt gggagttggg attgctttgg ggtacggagt
     5101 ggccttattt gacaaggttc gggtgcctca gacagaagaa ttggtgaatc aggtcaagga
     5161 catctcttct atttcagaga ttacctattc ggacgggacg gtgattgctt ccatagagag
     5221 tgatttgttg cgcacttcta tctcatctga gcaaatttcg gaaaatctga agaaggctat
     5281 cattgcgaca gaagatgaac actttaaaga acataagggt gtagtaccca aggcggtgat
     5341 tcgtgcgacc ttggggaaat ttgtaggttt gggttcctct agtgggggtt caaccttgac
     5401 ccagcaacta attaaacagc aggtggttgg ggatgcgccg accttggctc gtaaggcggc
     5461 agagattgtg gatgctcttg ccttggaacg cgccatgaat aaagatgaga ttttaacgac
     5521 ctatctcaat gtggctccct ttggccgaaa taataaggga cagaatattg caggggctcg
     5581 gcaagcagct gagggaattt tcggtgtaga tgccagtcag ttgactgttc ctcaagcagc
     5641 atttttagca ggacttccac agagtcccat tacttactct ccttatgaaa atactgggga
     5701 gttgaagagt gatgaagacc tagaaattgg cttaagacgg gctaaggcag ttctttacag
     5761 tatgtatcgt acaggtgcat taagcaaaga cgagtattct cagtacaagg attatgacct
     5821 taaacaggac tttttaccat cgggcacggt tacaggaatt tcacgagact atttatactt
     5881 tacaactttg gcagaagctc aagaacgtat gtatgactat ctagctcaga gagacaatgt
     5941 ctccgctaag gagttgaaaa atgaggcaac tcagaagttt tatcgagatt tggcagccaa
     6001 ggaaattgaa aatggtggtt ataagattac tactaccata gatcagaaaa ttcattctgc
     6061 catgcaaagt gcggttgctg attatggcta tcttttagac gatggaacag gtcgtgtaga
     6121 agtagggaat gtcttgatgg acaaccaaac aggtgctatt ctaggctttg taggtggtcg
     6181 taattatcaa gaaaatcaaa ataatcatgc ctttgatacc aaacgttcgc cagcttctac
     6241 taccaagccc ttgctggcct acggtattgc tattgaccag ggcttgatgg gaagtgaaac
     6301 gattctatct aactatccaa caaactttgc taatggcaat ccgattatgt atgctaatag
     6361 caagggaaca ggaatgatga ccttgggaga agctctgaac tattcatgga atatccctgc
     6421 ttactggacc tatcgtatgc tccgtgaaaa tggtgttgat gtcaagggtt atatggaaaa
     6481 gatgggttac gagattcctg agtacggtat tgagagcttg ccaatgggtg gtggtattga
     6541 agtcacagtt gcccagcata ccaatggcta tcagacctta gctaataatg gagtttatca
     6601 tcagaagcat gtgatttcaa agattgaagc agcagatggt agagtggtgt atgagtatca
     6661 ggataaaccg gttcaagtct attcaaaagc tactgcgacg attatgcagg gattgctacg
     6721 agaagttcta tcctctcgtg tgacaacaac cttcaagtct aacctgactt ctttaaatcc
     6781 tactctggct aatgcagatt ggattgggaa gactggtaca accaaccaag acgaaaatat
     6841 gtggctcatg ctttcgacac ctagattaac cctaggtggc tggattgggc atgatgataa
     6901 tcattcattg tcacgtagag caggttattc taataactct aattacatgg ctcatctggt
     6961 aaatgcgatt cagcaagctt ccccaagcat ttgggggaac gagcgctttg ctttagatcc
     7021 tagtgtagtg aaatcggaag tcttgaaatc aacaggtcaa aaaccaggga aggtttctgt
     7081 tgaaggaaaa gaagtagagg tcacaggttc gactgttacc agctattggg ctaataagtc
     7141 aggagcgcca gcgacaagtt atcgctttgc tattggcgga agtgatgcgg attatcagaa
     7201 tgcttggtct agtattgtgg ggagtctacc aactccatcc agctccagca gttcaagtag
     7261 tagttctagc gatagcagta actcaagtac tacacgacct tcttcttcaa gggcgagacg
     7321 ataattctct aaatgaagtg gccaatcaat ggattgccac ttttttcctt tcgtgttaca
     7381 ataagggtat gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat tcgctcctat
     7441 ccggcttaat atggggaatc tgtggaattt taggagagta cttctttact cattatcagg
     7501 tgtcttcggg ctggattacc tctatgcgtt tgacactggc agggagtctt gtactcattt
     7561 ggtctgcaat acaattaaaa tcgcaagtgc tagatatttg gcgagacaag aaaaattacc
     7621 tgcccttttt agcctatgct attttgggga ttttttcagt tcagtatttt ttctatctct
     7681 gtgtagaata ctcaaatgct acgacagcaa ctattttaca gtttattagc cctgttttta
     7741 tcctctttta caatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct gttttctatg
     7801 ttttggttgc catgctgggt gtttgcttga tggcgacaaa gggagatctc tctcagttat
     7861 ccatgacgcc gctagctctt ataacaggtt tgctgagtgc catgggtgtt atgtttaatg
     7921 ttatcttgcc ccaacctttt gctaagcgtt atggttttgt tcctacggtt gggtggggga
     7981 tgattttggc aggtttgttt agcaatgtcc tctcgccggt ttatcagctt tcctttactc
     8041 ttgatatttg gagtatcttg atttgcctca ttatcgcttt ctttggaacg gcttttgctt
     8101 ttttcatttc catgaaggct gtgtccttgg tttctccttt ggtggttgcc gttatcagtg
     8161 ccagtgaacc tctctcttct gctctcttga gtgttttgtt cttaggatta gtagtggatt
     8221 ggtccctcct tctagctata gccttgatta ttttacccat gatatttttg tctatagaag
     8281 aagcgaaaga aagtagataa aaagtctttt cttaattcta aaagtgtgct atactagaat
     8341 agtcaataaa acacggggag atagttgtga agagtgtttt taggttgtat cggtaggggc
     8401 ttgcttttac cgacagcacg ttttatctca catccctaaa aaatcatacc taaaaacaga
     8461 caaaaaggtt tcaaatttga ggcctttttt ggtagaatag gtatcattat aacgaaccag
     8521 gaggcaccta tgactgctac aaaaatgaac gctcaagaaa ttatccaatt tatcgccaat
     8581 gctgaaaaga aaaccagtgt caaagtaacc tttgaggggc aactcgcaac tgctgtgcct
     8641 agctctgttg tcaaactagg aaatgtccta ttcggagact ggaaggacgt ggctccgctt
     8701 cttgaaggtt tggtagaaaa tcaagattat gttgtcgagc aagatgctcg taattctgca
     8761 gttcctttgc tagataagcg tgctatcaac gctcgtatcg agccaggtgc tattatccgt
     8821 gaccaggtgg aaattggtga caatgctgtt atcatgatgg gagctgttat caatatcggt
     8881 gctgaaatcg gtgctggaac catgattgac atgggtgcca tccttggtgg ccgtgctatc
     8941 gttggaaaaa atagccacgt tggtgcaggt gcagttttgg caggtgtgat tgagccagct
     9001 agtgctgaac cagtccgtgt cggagacaat gttcttatcg gtgctaatgc agtggttatc
     9061 gaaggagtcc aaatcggtag tggttcagtt gtcgctgcag gagctatcgt tacccaagat
     9121 gtcccagaaa acgtggtagt agcaggtgtt ccagctcgta tcatcaaaga aattgatgcc
     9181 caaacccaac aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt gtaaaagtaa
     9241 aaaagaggcg gaaccctttt tccagcctct ttctgctata tcggaggaca gatagatgtt
     9301 agatttgatt cagactagac gagctttaca ccagattcca gagattggct tggaggagtt
     9361 caagactcag gcttatttgc tggatgtgat tgagaaattg actacgggca aggattttgt
     9421 tcaaattcgt acttggcgga cagggatttt ggtctacctg cagggaagtc agccggagcg
     9481 aaccattggt tggcggacag atattgatgg tctgcctatc gtcgaacaaa caggtctacc
     9541 ttttgcttct caacaccaag gtcgcatgca tgcctgtggc catgattttc atatgaccat
     9601 tgccttaggc tgtcttgagc gcgcccttga ggagcaaccc aagaataatc tgctctttct
     9661 atttcagcct gctgaagaaa atgaagctgg tggtatgctc atgtatgagg acggtgcttt
     9721 tggagattgg ttgccaaacc aattctatgg tctccatgtt cgtccagatt tgaaagtcgg
     9781 ccagattgcg actaatactc atacactctt tgcaggaact tgcgaggtga agatccgttt
     9841 caaaggcaaa ggtggccacg cagcttttcc tcatgaagcc aatgacgcct tggtggcggc
     9901 tagttacttt gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc caatcgaggg
     9961 agcagtggtg accttcggcg tttttcaagc tggaaccacc aacaatgtca tcacagacac
    10021 agctttttta catggaacta ttcgtgcctt gacacagaac atgagtctct tggtgcaaaa
    10081 gagggtaaaa acagttgcag aaggggttgc agctgccttt gatatggaag tcgaagtgga
    10141 actcaaacaa ggtggatacc tacctgttga gaacaatcca gccttggcgc gtgaactgat
    10201 ggacttcttt gacgaaaaag acggaatcga gttgattgat atcgaacctg ctatgacagg
    10261 cgaggacttt ggttatctcc tttcaaaggt tgatggtgtg atgttttggc taggtatcga
    10321 tagtccctac gctcttcatc accctcaaat gagtcctaag gaagaagtct tagctattgg
    10381 ggtggctgcg gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg cttgtctatg
    10441 aaatcggaat tacgcaagca agtcttgcaa ggaatgaagg ctatatctca agaacaaaaa
    10501 caggctatag accaagcttt aaccgagcga attttacaac acccctttta tcaagaagcc
    10561 aaggtcatcg caacctacct ctctttttct catgaatttc aaacgcggga actgattgag
    10621 caggcgttga aggacggcaa gagggttttg acacctaaga cctatcccaa ggggcgcatg
    10681 gactttgtgg tctatgatcc gcaacagttg gtaaaaactt cctttggatt actggagcca
    10741 cagggagatt tggaagttgt ggatgtttca aagattgatt tgattcatgt tcctggtctg
    10801 gcttttacga cgaaaggata tcggatagga tacggtggag gctattatga ccgctatctg
    10861 gaacattttt ctggtcgtgc tttgagtacg atatatcctt gtcaaattca ggactttata
    10921 cctgaaaacc atgatattcc tgttcaggag gtattaattg atgaaggaaa tctttgatag
    10981 acgttaccct gtgacgagtt tcttcctctt agtgacggcc ttggtatttt tactaatgtt
    11041 ggtcactgca ggcggaaact ttgacagggc agatacatta tttcgatttg gagccatgta
    11101 tgggccagct attcgcctct ttcccgagca ggtttggcgt ctcttgtctg ccatttttgt
    11161 tcatattggg tgggaacatt tcattgttaa tatgctttca ctttattatc ttggaaggca
    11221 ggtagaggag attttcggtt ctaagcagtt tttctttctc tatcttttat caggaatgat
    11281 gggcaatctc tttgtttttg tatttagtcc taaatcctta gcagcaggcg cctctacctc
    11341 tctttatggg ctatttgccg cgattattgt tcttcgctat gcaactcgca atccttatat
    11401 ccaacagcta gggcaatcct atctgacact ttttgtggtt aacattattg gaagtgttct
    11461 gattccagga atcagcctag caggccatat cggtggtgca gttggtggcg catttctagc
    11521 agttatcttt ccagttagag gagaaaaacg gatgtataac accagccaga gattaggagc
    11581 ggtagtcttg ttcgtaggac tcgccatttt gcttttctac aagggaatgg gaatgtgacg
    11641 aagttgaaag aaaatttgtg taatgaaaaa agataaggca ttttttgaac cttatctttt
    11701 tattttattc cttctcagtc aattcttttc caagttggat gaggtaattc ttcaaatcat
    11761 ctttgacttg tggatgtttg agggcgtagt caatagatgt tttcataaag ccaaacttgt
    11821 ctccgacatc gtaacgagcc ccattgaact cacgagcaaa tacacgttgt gttttattga
    11881 gggtgtcgat tgcatctgtc agctgaattt catttcctgc acctggagct tgcttttcga
    11941 gaatctcaaa aatttcaggc gtgaggaggt agcgtccgat aatagcaagg tcgctaggag
    12001 cgtcctctgg agctggtttt tcaacaaagg tttcaacact gtaaagacca tcttttcctt
    12061 cgccttgcgg agcaataacc ccgtaagcag atacttcgtc atgagggact ggcatgacag
    12121 cgatagtaga cgcgtgggta cgctcgtagt catccatgag ttgtttggta agtggaacag
    12181 ccttttcgtc tgtgatatcc atcaagtcat cacccagcat aacaacaaaa ggttcatttc
    12241 caacgaaagc cttggcttgc aaaacagcat ctccgagacc gcgtggatga gtttggcgga
    12301 taaaatgcag acgcatgcca gttgtttcat caactagctt caaaagatct gttttccctt
    12361 tttctttgag gttatattcc aattcgaagt ttgaatcgaa gtggtcctca atagaacgtt
    12421 ttgatttacc agtgacaact agaatatctt caatacctga tttgagagcc tcttccacga
    12481 taaactggat agttggtttg tctacgattg gcaacatttc tttggcaagg gccttggttg
    12541 ctggtaaaaa tcgagttcct agtccagcag cagggataac tgcctttcta acttttgatg
    12601 tcataaaaat cctttctata gagggttaag accactcatt ttctgcttta aattcattgt
    12661 tcatgatgtc ataaatggca tctttgatat tggttccgtg ataaataact tggtaaatag
    12721 cctgtgtaat gggcatatag actccaagtt cttgggctag ttcataggct gctcgagtcg
    12781 ttgaaattcc ttcgattacc atgcccatat tagcttctat atcagctagg gattctcctc
    12841 gtccgagagc atctccagct ttccagttac gagagtggat ggaagttccc gttacgatca
    12901 aatctcccac accagataag ccgctatagg tcaatggact ggccccgagt gctaccccta
    12961 ggcgggtgat ttctgctaaa cctcgagcga tgatggctgc cttagcatta tcaccaaatc
    13021 caagaccatg taaagctcca gcaccgacag caataatatt tttaagagca ccagcagtct
    13081 caaccccgat aacatccgta ttggtataaa gtcggaagta gtgattacta aatagctcct
    13141 gaacgtattg agctgtttgt aaatctttag aagcagcagt tattaaagtt aggtcacgca
    13201 caatggtctc ttctgcatga ctaggccctg aaacaacgac gatatcacta cggagatgtt
    13261 caggaatttc ttcttcaaga atggttgata atcgtttatg gctatcaggt tctaatccct
    13321 ttgatgcgtg catgatgata accttatggt ccaaggtttg tgcaacttgc tgggcaacaa
    13381 gtcgtgtcac ttttgttggg acaacaaaca aaatcgcatc cacatttttc aatgtttctg
    13441 ctaagtcggt gtaggcaatg atattttcgt ctagaacgac atctttaaag tagtgcttat
    13501 tagtatggtg tgtattaatt tcattgattt gctcgggaag atttccccaa atacgtacct
    13561 cgtgtccatt gtcatttaag acttgtgaaa gggcggttcc ccaagaacca ggccccaaga
    13621 cggcgacggt ttgtttttcc atgatttcct ccttgataga tttctttctc ttattctatc
    13681 atattctagg ggattttgca cttgcattac tggggtatgg tggaaaaata cacaaagacc
    13741 gagatgaagg gataaactct tagtctttag ttaaagtgag aagaaatctg atagatagtt
    13801 tgattcagta tatgcttata atagaggtaa acaactcagg aagttcttgt aggttgcgag
    13861 agtttggcga aaaaattaaa agattacgtt tggctaaaaa aatcagtcgt tcagaatttt
    13921 gtggtgatga gtctgaatta agtatccgtc aattaattag aattgaaaat ggagaatcca
    13981 gaccaatact aacaaagtta aaatatattg ctgaacgttt ggaggttgaa gattacaagt
    14041 tgatgccaag ttatatagag ttggataagg aatacctaga attgaagtat ttcttgatga
    14101 ggactcctac atacgaagat gaaactatcg cccaaaagaa agagagtgtt tttgataaga
    14161 tttttgaaga gtattatgat aggctacctg aggaagaaag atttatcatc ccaaattatt
    14221 catatctggc actaacgaac tacacagttc aaaaattacc agaaaagcta gttgaaatac
    14281 tgtccttctg gtgattttgc ttaatttctg atgttcgaga catgattgag gagatttgtc
    14341 ttgatttttt cctaaaaaag ggcagactcc tcccttggtt tgatgctcga tttttaaaat
    14401 aaggtgactt attctgttag gcatgttttc ccctgccctc tagctctata tggaacaggg
    14461 agtatcagat ttatctggca gattgtatca aataaggctt gaaactgttt tgaataggcg
    14521 tatagacttg agaatttgag aatatgtcgt ctagcagtag agacatattt tccggcaata
    14581 tgaaggaaga gacgtcgaaa acgcttgata gtcaaggcct ttacttcatc accagctagc
    14641 tgttttaaaa agaggtagag attataagcc agacagccca tcatcatacg tacttcattc
    14701 ttaatcatgg tcgaactatc tgtcttatcc ccaaagaatc ctgctttcct ttctttgata
    14761 aagttttcag cattccctcg ttcacgatag aattgaaaca gatcctcact atctacactg
    14821 cttaaattgg tcaaatgaac ttttttacaa ccataaaaaa gagcacttaa tcgtactctt
    14881 ctcttttaag gattagttga attaattcaa atccactagt tctcctgttt ctaggtagac
    14941 taggcgttca caaatgttag caatgtaatc agcgaagcgt tccagatgcc ctatgatata
    15001 aaggtattgt gttccattgg gaattgaggt ttcttggtct ttcataagtc caatgatttc
    15061 ctttgataag gcataataat attggtcaat ctgttcatct ttttgagcaa tactaatagc
    15121 ttttgaggtt tggtgcaaag gaaaggcaac caataaatcg gatagcatgc tgagggataa
    15181 tttacccatt tggtgtaact gttcttcgtc aggggctagt tgattttctt ttagttgcaa
    15241 aacagcttta gcaatgcctg ccatatggtc tcccatacgt tcaaggtctg aacaagaaga
    15301 catgatgcta atcacaaatc gaaggtcaga cacttgtggc tgctgcaagg ccaacaaacg
    15361 ggcacaggtc aattcgatag cgctttgacc ttggttgata gcatgatcct tattgataat
    15421 tagctctgcc atctccttgt ctttggaggc taaggccagt aaggcttttg aagctgtttc
    15481 aaggacaagt tgccctagtc ctaaaaagga ttgttctaat tcatgcaatt ctaagtcaaa
    15541 ttgatttctc ataggttttt ccttccttat ccgaaccgtc ctgaaatata gtcttctgtg
    15601 cgctgatctt ttggattggt aaacacgtca acggtatctc caaattcgca aatttctcct
    15661 gttaagaaaa aagcagtttt atctgaaata cgtgaagctt gttgcatgtt atgggtaaca
    15721 atgataatcg tataatcctt ttttagttgc tgaatgaggt cttcaatttt taaagtggag
    15781 atagggtcta aggctgaagt cggctcatcc attaacagaa tatcaggttc tactgctaaa
    15841 gctcgcgcaa tgcaaaggcg ttgctgctga ccgccagata aggacatggc actcttttta
    15901 agatcatctt tgacttcttc ccaaatggct gcccctttta aagatttctc cactaaggca
    15961 tctaattgtt ttttgtctcg aataccatgt gtccttggac cataagccac gttatcatag
    16021 atagacatgg caaagggatt aggctgttga aaaaccatcc ctacacgctt gcgtagctga
    16081 ttaaggttga atttgctact ataaatatct tgctcatcta agaggacttg gccttcaata
    16141 tggcaagaag ggaccaaatc gttcatccga ttaagggttt ttagaaaagt tgattttcca
    16201 caaccagatg ggcctatcaa ggcagtaatc tgtctttctg gtaattgaat cgaaatattt
    16261 tttaaggctt gaaaatcccc gtaaaataag tctaggtgtc tgactgaaaa tgttcccata
    16321 ctaggaagct cctttcacaa gttttcgaga taataagctt gatagagtat ttatcattaa
    16381 aacagtaata atcaaaatca caccggtagc ataggcttca ttgacatgta gcccctcact
    16441 tgacagcata tacatatgca gggctagaga acgacctgaa gacatgagac tacttggcgt
    16501 attggtagag gtacctaatg tatacatgag ggcagctgtc tcaccaacga tacggccaat
    16561 agctagtatc actccagcta aaatacctgg catggcaact ggtagaacaa ttctaaaaac
    16621 agtccgtaac ttacctgccc caagtccata acttgcttga cgcatgctat cactaacaga
    16681 taaaagggct tcttctgttg agcgaataat gactggcaac accatgatga ctgaggttaa
    16741 gattcctgat aacagagagt attgaaaacc taagaagact acaaagaaga gcatgccaaa
    16801 cagaccaaaa acaatggaag gaatcccaga caaggtatct gaggccaatc gcatgatttt
    16861 aacacaaagg gaatcttttt ttgtatattc cacaagataa aaaccagcaa aaatccctat
    16921 gggcaaggct aaaagaagag caccaaagac cagaataacg gtggaaataa tcgctggcat
    16981 aagggaaatg ttctcagaag tataagtcca agaaaagagg gatagactta gatgaggtaa
    17041 gcctttgatg aggataaaac caatgattaa aaagagagag ccaaaggtta aagctgaaaa
    17101 acaataaacg agaagtttta gcaggtattt actcataaga tgattttcct ttcaagtagg
    17161 caaagtaggc attaatcaag agaataagga aaaagagaac tgctgaggtt gcaataaggg
    17221 cttccctatg ctgacctgat gcgtaagcca tttccagaac aatattggtt gttaaggttc
    17281 tggttcctga aaagagtcca cttggaataa tcggctggtt gcctgccacc aaaataactg
    17341 ccatggtttc acctactgcg cgaccgattc ctaaaataac tgctgataaa ataccagatc
    17401 tcgcagctgg caagatgaca ctaaaaatac tccgttcatg actagctcct agagccaagc
    17461 taccagaata atacgttttg ggaactgttc ggatagcaga ttctgacaaa ctgataatgg
    17521 ttggcaaaat cattattcct aatagtaacg aagcggttag gacactcatg ccatttccta
    17581 aaaagcttct aatccaaggc accaataatt gtaggccgaa aaaaccataa acaatagatg
    17641 gaatggccgc catcaagttg atagctgatt ttaagaagcc atagacgggc tttggacaat
    17701 aataaaccat aaacaccgat gtcaagatgc ctgttggcac cccaatcaca atcgctccta
    17761 aggtaattaa taaggaacca acgatcattg gtaaaatacc atagcttgcc ggaatgttcg
    17821 ttggcgacca atcactgcct aataaaaaac gggcaaagcc gtagttagcc atgaaaggta
    17881 agccattact aaaaataaag aaacagatta gcaaaatagc tacaacagct actgttgcac
    17941 tcatgaaaaa aattgcccta aaaactgctt ctttgaaggc ttgttttgtc acatcttgtc
    18001 ctttctagtg aagaaagtaa gggagatacg acacctccct acttgccttc tttatcttat
    18061 tgtacgatga aacgtctgca tctctttaga gatttatgga gcaaacattt tatttaatct
    18121 tgtcccaggt ggttaatttg ccactaaaaa cgtctgcaag ttcagccata ctgacttggc
    18181 ttgccttatt gtcattattg accacaacag caataccgtc taaagcaata gcatcatggg
    18241 tgagactctt accttcttca ggagttaatt ccctagaaac cataccaata tcagcggttt
    18301 tctccttaac agcggtaata cctgctgaag acccattaga ggtaatatca atcgtaactt
    18361 ctggattttc ttttttataa gcttctgcta atttttccat taaagaagat actgaagtgg
    18421 aacctacaac agacaacttg cctgataagt gttggcttgt atattctgtg gtttcggttt
    18481 tagcttcaat aaatttatta tctgtgacca cttgttgacc ttgtttggag tggataaagc
    18541 tgataaaatc ttgacctagc ttggaaagat tagaagacca aacaatgttg aagggacgtt
    18601 gaagagggta ttcaccatct aaaactgtgt ctcgactagc cttgacacca tcaatctcta
    18661 aagccttgac agattttgtt aaagatccca aggagatgta gccgatagca ttagcattcc
    18721 cttgaactgc tgagagaaca ccttctgtac tattttgaat cacagctgtt ttggcagtgt
    18781 tgtcaatttt tttatcaccg tcttttttga gaatccctgt gatttctgtg aaggcacccc
    18841 gtgttccaga gccattttct cgtgaaatca cctcaatcgt tcctgaagct gactgtttgg
    18901 aagcagctga ctgattgcca caggcaacaa gcccaaatcc tgataagcca atggctgcaa
    18961 gagtaagcat ttttttgaat ttcataataa tcacctttat ctctatgtat ttttcttgtg
    19021 taggcttact acatttatag tctaacaagt ctttgtaaag gtttatccct gattcatgta
    19081 aagattgtgt aaagaatcaa aaaaagccac ttttgaaaaa tggctgctcc taaaaatagc
    19141 tttaaaaatt attagtcctg tgcgaaagat tggttaggaa gaaaaatcgt gaagcaactg
    19201 cctctgccaa gctgactcgt caccgtgact tggccaccta ataattgact gagttctttg
    19261 acaatggcaa ggccaagacc agtgccacca gtttgtctgc ttcgaccttt attaactcgg
    19321 taaaaacgtt caaaaatacg atcctgctct aattgactaa taccaatccc tgtatctgat
    19381 acagaaatct taatgccttc gttcaccttt tgggtcttga cctcaatttt ccccccttgt
    19441 tcagtgtaac ggatggcatt ggataaaaga ttgagtaaga tttgggaaag taattgacta
    19501 tctgatacga gggtgacatc atctggcacc tgcaccttta gctgtaaatc cttcttcttg
    19561 agctgaggtt gcaagctttg agtcaaatcc tgtacaaatt ctgccaaaga aagggtcgtc
    19621 cattgtatag gcatttgttg agccttagat aaggtaagaa gatgctcaac aatatgctca
    19681 agacgcaaac tttctttgta aataatgtct agaaagtcat ccttgagcgc ttcttcttca
    19741 gctgacatcc ccttaatggt ttcagcaaag cccttaatcg aagtaactgg tgtcctcaat
    19801 tcatgggagg catttgagac aaaggctaaa tttaactttt cataagttct aatcgttgtt
    19861 aaatcatata gcaagacgag cacagcttcc acagattggg tggggctaaa aacgggaact
    19921 gctgtcactt ctaaaatcaa gtcaccctca tgaaacccac ttacttcttg ttttaacctt
    19981 gttttttgat caaaggcttg gtgaactaaa ttccgaatat ccatccgttt gaggtcatca
    20041 agtgaactta tgtcgccgtc cacatcggga aaataatgag gcagagagcg actggataat
    20101 aacatctgac cttgagcgga aactaaaaac gtccccatgg ttaggtgcga cagaagaacc
    20161 tccattgttt cggctagatc cttgtattgc tgatcctgtt gggagacttt ggtttttagg
    20221 ccagacacat actgagccaa agactttaag tcttcttgcc ctttttctaa aaagtattca
    20281 ctactggtca agagaggttg gtgcaaggtc tcaaaagcaa cttcccattt ccaaaggcaa
    20341 aagagccagt agccacctag tcccaaagaa agggctagaa gaaagagacc gatgccttta
    20401 ctgatccaag ttaatgccat ccctgcaatc agaatgaggc taacacttag attgactagc
    20461 caaaattgaa ggtagcgttt catctataac tccttgaact tataaccata accccgaatg
    20521 gttcgaataa attgaggggc tttaggattg tcttcaattt tttccctcaa cttaccaata
    20581 tgaacgtcca ccaaacgtgt ttcctgccca aagtcatacc cccagatacg ttccaaaaga
    20641 cgctctctag tcagtgtcat gttgggatgt ttcataagat agagcaagag ttcaaattct
    20701 tttggggtca aactcagtaa cttattcgcc ttgtagactt catgacgctc agggtatact
    20761 ttcaaggtcc caaatagcca agaatcgtca gcgatattat ctgaatcatc tccttcttgt
    20821 tctcctttag ttcgcctgag gacagccttg acacgcgcca gcaattctct agggctaaaa
    20881 ggcttggtca ggtagtcatc agcccctaat tccaaggcca aaaccttatc aaattcatca
    20941 cttttcgcag aaaccatcat aattggagtt ttgacgcctt tggctctcag ccgcttacaa
    21001 acttccatgc catctaattg tggtaacatg atatcaagca agataaaatc aaagggttct
    21061 gtttctgcca aagctaaggc cttccgtcca tttgttacca attgagtaga aaagccttcc
    21121 ttacttaaat ggtagtcaag caatttcaga atgtgttctt catcatccac taataagact
    21181 tgttttgtca tctattatct cctattggta acattataac acaattatca gaaatcctaa
    21241 cattgctaaa tcagattaaa tttgcttatc aagactagta tctggtcaaa cgctcaatca
    21301 tctccttgtg ctctggatag gtcgccagta gatctaccct ttcaaataat tcaaaatcct
    21361 caaattcaaa accaggagca acaagacaag aaaccagagc atcatcctta tcaactgttg
    21421 atccccaaat agtgccctta ggaacacagt agtgaagttg ttgccctttg gatatgtcca
    21481 ggcctaaagt gactacttcg tagtgaccat ctgctgtaat catgtgaaca gtaagtgggg
    21541 atcctgcatg aaaataccag atttcatctg ctgtcaatcg gtgaaaatgt gaaggattcg
    21601 tttcttctta ataagaaata aatactggta taaagcgccc ttcccttacc agcaaggttt
    21661 atagtgtctg aagctttttt tgtttgtcta aaatagccac cttcaacatg gggagctaac
    21721 tctagagttc ttatcaagtc ttctttatcc gtcggagcca atgggttgaa gtaactcttg
    21781 ttcaaagtgg tgttacgatt tcaagaactc ctctcagctc tgaggacacg gtaatgattg
    21841 atgcgacgga agtacaaatc aatcgcccta aaaaaagaat tagcgaatca ttctggtaaa
    21901 aagaaatttc acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct
    21961 ttggatatcg ctgtgaacta ttgtcatgat ataaagttgt tcaaaatgag tcgcagaaat
    22021 atcggacaag ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat
    22081 cctcgagcac aa
//
LOCUS       DAVDFK010000031        22077 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.31, whole genome shotgun sequence.
ACCESSION   DAVDFK010000031 DAVDFK010000000
VERSION     DAVDFK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.31"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(344..1540)
                     /gene="tuf"
                     /locus_tag="VUR04_001497"
     CDS             complement(344..1540)
                     /gene="tuf"
                     /locus_tag="VUR04_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET5341373.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2473..3342)
                     /locus_tag="VUR04_001498"
     CDS             complement(2473..3342)
                     /locus_tag="VUR04_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET5341374.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3566..4216)
                     /locus_tag="VUR04_001499"
     CDS             complement(3566..4216)
                     /locus_tag="VUR04_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5341375.1"
                     /translation="MVSKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKEPDIPTVESQEVTSDSSDKEIMVRYDRL
                     STPDKPTPEPGTPGEPAPEKPIPQPNPEYPSVPTPNPELPNQETPIPESTPEPGTPKT
                     ETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(4174..5280)
                     /locus_tag="VUR04_001500"
     CDS             complement(4174..5280)
                     /locus_tag="VUR04_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET5341376.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5391..5645)
                     /locus_tag="VUR04_001501"
     CDS             complement(5391..5645)
                     /locus_tag="VUR04_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341377.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6003..6536)
                     /locus_tag="VUR04_001502"
     CDS             complement(6003..6536)
                     /locus_tag="VUR04_001502"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET5341378.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYT
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTELLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKYFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6523..6738)
                     /locus_tag="VUR04_001503"
     CDS             complement(6523..6738)
                     /locus_tag="VUR04_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341379.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHLDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6719..6847)
                     /locus_tag="VUR04_001504"
     CDS             complement(6719..6847)
                     /locus_tag="VUR04_001504"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET5341380.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKVFGVGVKLSSRGKRKT"
     gene            7081..8799
                     /locus_tag="VUR04_001505"
     CDS             7081..8799
                     /locus_tag="VUR04_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET5341381.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8910..9257
                     /locus_tag="VUR04_001506"
     CDS             8910..9257
                     /locus_tag="VUR04_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5341382.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEASQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9536..10372)
                     /locus_tag="VUR04_001507"
     CDS             complement(9536..10372)
                     /locus_tag="VUR04_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5341383.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKLSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10385..11014)
                     /locus_tag="VUR04_001508"
     CDS             complement(10385..11014)
                     /locus_tag="VUR04_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5341384.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11024..11665)
                     /locus_tag="VUR04_001509"
     CDS             complement(11024..11665)
                     /locus_tag="VUR04_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5341385.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFTLQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11811..13040)
                     /locus_tag="VUR04_001510"
     CDS             complement(11811..13040)
                     /locus_tag="VUR04_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET5341386.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDAISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYMDQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGGLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13030..14196)
                     /locus_tag="VUR04_001511"
     CDS             complement(13030..14196)
                     /locus_tag="VUR04_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET5341387.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIVITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14340..15353
                     /locus_tag="VUR04_001512"
     CDS             14340..15353
                     /locus_tag="VUR04_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET5341388.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLAPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15398..15817)
                     /locus_tag="VUR04_001513"
     CDS             complement(15398..15817)
                     /locus_tag="VUR04_001513"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET5341389.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15828..17234)
                     /gene="atpD"
                     /locus_tag="VUR04_001514"
     CDS             complement(15828..17234)
                     /gene="atpD"
                     /locus_tag="VUR04_001514"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET5341390.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17320..18198)
                     /locus_tag="VUR04_001515"
     CDS             complement(17320..18198)
                     /locus_tag="VUR04_001515"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET5341391.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18214..19719)
                     /locus_tag="VUR04_001516"
     CDS             complement(18214..19719)
                     /locus_tag="VUR04_001516"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET5341392.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19734..20270)
                     /locus_tag="VUR04_001517"
     CDS             complement(19734..20270)
                     /locus_tag="VUR04_001517"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET5341393.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20270..20764)
                     /gene="atpF"
                     /locus_tag="VUR04_001518"
     CDS             complement(20270..20764)
                     /gene="atpF"
                     /locus_tag="VUR04_001518"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET5341394.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20778..21494)
                     /gene="atpB"
                     /locus_tag="VUR04_001519"
     CDS             complement(20778..21494)
                     /gene="atpB"
                     /locus_tag="VUR04_001519"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET5341395.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21529..21729)
                     /locus_tag="VUR04_001520"
     CDS             complement(21529..21729)
                     /locus_tag="VUR04_001520"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET5341396.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21804..>22077)
                     /locus_tag="VUR04_001521"
     CDS             complement(21804..>22077)
                     /locus_tag="VUR04_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5341397.1"
                     /translation="NVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         6572 a         4756 c         4029 g         6720 t
ORIGIN      
        1 atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata gatgttactg
       61 acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt agctaacttt
      121 ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat cgatttctaa
      181 caatgtttta gaagtagatg tgtactattc tagtttcaat atattatagt ttgctctttg
      241 attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca agattctttt
      301 agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct tcgatttctg
      361 taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta gtaccttgtt
      421 ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca ggcattacca
      481 tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg aagtagaatt
      541 gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta gtaaggatgt
      601 agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg ataacttgtc
      661 cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta tctccagcaa
      721 gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct ttttgagttt
      781 cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca cggtcgatac
      841 gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact ggaagaagca
      901 atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg ttcatcaatt
      961 ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct gaaccttgga
     1021 taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg atttccattt
     1081 caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg aagacgataa
     1141 ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc
     1201 cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca gtgatcatgt
     1261 ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt ttttcagttt
     1321 cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct ggagcagcat
     1381 cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt gccaaaacag
     1441 ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata gtaccaatgt
     1501 taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa gcctccaata
     1561 aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac tattttatca
     1621 aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt ggtaaaaatt
     1681 taactaacta atagaaagta ctaaatagac ttatccttca aggagttttc agcattatcc
     1741 atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa tgaaacaaga
     1801 atagggcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aagttgaggt
     1861 gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa caacctgcgg
     1921 ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat aaaacgataa
     1981 caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta atcgcttatt
     2041 ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc aattcctcac
     2101 aatgtttgag aaagaaggga agactattcc aacttcaacc cactataaag cagacttaca
     2161 ggatagggaa cccatctccg ataatattcc gataatatat agtagaatga aaactgcaca
     2221 atttgattgg agaattcaaa ccaatttcta acaatgtttt agaaacaagg gtctattatt
     2281 tcaactgcaa cctactatag cccattgaag ctggaatagc ccactgagac ttctaaacca
     2341 ctgctggaga ggagtttgtt tagagtttgt ttagagtttc tttcatttcc ctaaaaaatc
     2401 aaaaagagag aaccagtctg atcctctctt acttatagat ggtgttcact caaatgttaa
     2461 aggagctatt tcttagagat aaaggaattt gaatacagct actgccgcaa ttgctgctgc
     2521 gataggtgct actactggta cccaagaata ccaccatttt gaatcgcctt tatgctcacc
     2581 aagaactgat tttggaagaa aagcatgaag gagacgtggt cccaagtcac gggctgggtt
     2641 caaggcaggt cctgtaggtc ctccaagtga tgttaccaaa gccataacga ggaatccaag
     2701 tgccaagtga gccacagaaa gtcctgaagc agtgtgtgga gccacctgtg ctttaatagc
     2761 caagtcagaa aaatcaactg tttgtcctgc ttctattgcc ttttgtttca tgaattgaag
     2821 cacttcagca ccaaagaagt ttttagtcaa accaagagct gcaaagaaca aaacaaatga
     2881 accaacaaac tcattaatca aaccattgac agttgctgca tagcgacttt cttttgtacc
     2941 atggtcaata cttgaaatag ttgagaaagt tcccaagatg ttatttgggt tttcagtttt
     3001 caagtagaat ggacggtatg ttgccacaac taaggcttgg ccaaagatag cccccaagac
     3061 ttgcgcgata atgtaaggta ccacttgtgc ccaagggaaa agaccgctaa ctgcaagccc
     3121 tagagtgaaa gcagggttga tgtgattccc agatacgtta ccaaacatca aggctgggat
     3181 cataaccccc ataccataac caacagcgat gacgatccag ccactttggt gacctttcgt
     3241 acctttaagt tcaacgttgg caactgcacc attcccaaga atgatcaaaa tggcagttcc
     3301 caaaaattca gtggcatact tcagtgccca tgtgaaatcc atttgctaga ttctccttaa
     3361 aattttttag atattcctta ttttatcaat ttttacccta tttagcaact gatttctgga
     3421 aatattttta aaaaaatagg attcatagtt tcccagttca acggacttgt aagcgttttt
     3481 attcttcacg aaagagctcg ttctcaaaac caggaaaaaa gcccacatct gtgagctttt
     3541 ccttgttcct agattctaaa atctattatt tttcatcttc ttttttcttg aagaatccta
     3601 atcctagacc agctaacaag gtcatgatac cagcactagc caaggtagca ttagcttctg
     3661 tacctgtgtt tggcaattcc tctctcttac ctgtctcata agtcggaact tctgggtctg
     3721 gattcactgg agtttcagtt tttggagtac ctggttctgg agttgactct ggtattggag
     3781 tctcttgatt tggtagttct gggtttggtg tcggaacact tggatactct ggatttggtt
     3841 gtgggattgg tttttctgga gccggttcac ctggagtacc tggttctgga gttggtttat
     3901 ctggtgttga taagcggtca taccttacca ttatttcttt atcactagag tctgacgtaa
     3961 cttcttgtga ttcaactgtt ggaatatctg gctctttgta cttgtcaatc ttaccagata
     4021 taacctcgtc ccagtttcct gttgtccatt caccgtaggt tacaactccc gtgaccttgt
     4081 tctcagtttt tgtacggctt aaggttacag gttgaacaac atcttctttt acattttggt
     4141 tcgtaacttt atcaacgtaa tgaatgatac gcgttatagt cttcgtctca gtagaggttg
     4201 ctgttttgga aaccactgtt tcctcaacat tctcacggta gtaatagtca actgttgcac
     4261 cgtcttctgg tacgcatttg caggagttgc taccaaggtg tatgttgttt tccttgtgat
     4321 aactcggtct tctttgtcct cagttgttgt tttcccttca atagtttttg attctgtggt
     4381 atactcagaa cctatcgcta aatcagcttt tataacagac tctgccaact tctcttggct
     4441 accttcttta tagtaattgg ctgttactgt agcagtggtt ggcgcttcgc tttctctata
     4501 aactaaggtc actgttctac cttcgcttac aatattccca gttaaacttg cagaatttgt
     4561 atctgcttct ttaaaagtat aatattttcc gtcagtagta gtcatgctac tgagtttttt
     4621 atctgtgaca ttatagctgg taccaatcag ttgtttttta ttggtaatgt aggttccgtc
     4681 actttctttt tctccaattc cagtatcatt tttcaatgat agcaaacgcc cttgttcatc
     4741 aacatagcga actttcacat tttctgagat tagttctgcc aattctgagg tttttttctt
     4801 tttcttgatt tcttcggtta ttttcccttt ctcttcttcg ggaatattta gttttggaat
     4861 gattttttca acaacggttc gtgatggttc cacagtatct tggatgactg aaaagtcagc
     4921 tagaattggg agattatact gaacacggtg actttgagtg tttactccta ctctttcatt
     4981 attctctgaa aatacttgta cggtataaga aacaacatct tttcctaata gaacatcccc
     5041 agtagagaaa tagccgcctt ttcctagttt gctatctcca gagcccactt ctttcctaat
     5101 cttatcagat agttttttac cagttagtac attcgttcgc acaatccctt tgtctacccc
     5161 tacaaagtgg gagaactttt tgaactcttc agaaccagat ctagcccaac cattattaag
     5221 ggcatttgct tttgtatttg tattctctct caaaggtttg gcgattagaa ttatattcat
     5281 cggcgcttag agttgctgct atatctgact cttgaatacc aacttcctta ctaccatttc
     5341 tagcggcagt atatgtgtat ttatctgttt ctacttctag ctgattatcc ttaacatgat
     5401 aggtaatttt ctcctggtat aagagtcttc agtagtttat atgctctgtc atcatcttta
     5461 gctttagaag cagctgagtt tagccaagtt ggggtattag gagtatcttt atcagcctgt
     5521 ttcaagacat tattcaagtc atttgctagc ctattggtta tcctcactgt gaaagttttc
     5581 ttccagtctg aaccactttt attagactta gatatgctca tgaaatcctg gtcaacattc
     5641 aacacaatat cgccttgttt tttagcatct tccgttgctt ctgcttcaaa ttgatcatgg
     5701 agtttttgtt gctctggtgt atagtttttt tatttacacg atttaatgta ctatttttta
     5761 ttttagtatt aagaactcca ttaatacgat ttttaaattc tgcttcaaaa aatcccttaa
     5821 tttgttggtg cgcaagttca acattcaaac ctttcttata caagtcttca ttctgataca
     5881 agtcttcatt ctgaacgatt tcggctacac ggtgaatggt ttgatcgtat accgtcttct
     5941 cttaaccagc agtatcctta gttttaatga ctactcgata ggttccttta gaaccgttat
     6001 agtcatctag ttttaaaaaa gcattccaaa cattcaaaaa tagttggaac ttcccttaat
     6061 aaatccgtca ctttcttttt caagatagcc caagcttgct caataggatt caaatccggt
     6121 gaataaggtg gtagaggtaa gaaaaagtat ttatcttgga tgcagagttc atccaaaatg
     6181 ttcttgggat gaaaactagc attgcccatg acaataacat gaggtgtctt caaagcaggc
     6241 aggagttctg ttttgaacca ctccacaaag aaatcgcttg tcatgctttt cttgtaaatc
     6301 atgggagcta taaactctcc gtctacttgt cctgcaacaa ttgaagttcg ctcaaaacga
     6361 cgtccgctaa tcttttcata gactttctcc cctctaggag cccgtgtata aggacgatag
     6421 aggtagcggt cgattcctgt ttcatcaata tatacgattg gtaaatcttt taggttatcc
     6481 aaaatatcaa gaaactcagc gactttctct ggctcttgtt ccttaaagct cgtcatcttt
     6541 ttttaaagtg accttaatct gctttaaagc tgcccatact gaaggaacag cacaatcaaa
     6601 atgtgccgca atttcccgta aaaaagcatc tagatgagcc tctacaaagg ctttcaattc
     6661 ctctaaagga atctttcggt ttttgacaac tcgctttttc ctctctatgt gtccttgttc
     6721 acgtctttct tttcccacgt gaagagagtt tgacgccaac accaaaaacc ttggctgcct
     6781 cgacatggct gtgcccctct ttgatgtaat ctaatgctcg ctgtttaaaa tcagtactat
     6841 atgccatagc tttattataa catgcttgtt tgaaactaaa caactatatc aatgttttgt
     6901 tatgagaaga cttacttttt ttactgaaat tgaatttttc ctagcctcaa catcatataa
     6961 ccccaaaatt caatctgacc tggtttgaag agattttcga agcagataag attttactaa
     7021 aactaaaaaa aatgatataa tcaaactgat taaatgtttt aaaaataaag gagaatttga
     7081 atgtcttacc aagaaaatta ccagaaatgg gttgattttg tggagcttcc tgactacctt
     7141 cgtcaagatt tggaaaatat ggacgaaaaa actaaggaag atgccttcta tacaaatctt
     7201 gaatttggta ctgcaggtat gcgtggcttg gttggtgctg gtacaaaccg tatcaacatc
     7261 tacgttgttc gccaagctac tgaaggattg gctcgtttga ttgagtcaaa aggtggaaac
     7321 gagaaagaac gcggtgtagc aattgcctac gatagccgtc acttctcacc tgagtttgcc
     7381 tttgaatctg cggcagttct tgctaaacac ggcatcaaat cttacgtatt tgaaagcctt
     7441 cgtccgactc cagaactatc atttgcagtt cgtcatctca actgtttcgc aggtatcatg
     7501 gtcacagcca gccacaaccc tgctccattt aacggttaca aggtttacgg tgaagacggt
     7561 ggacaaatgc ctccacacga tgcggacgct ttgactactt atatccgtgc aatcgaaaac
     7621 ccatttgcag ttgaagttgc tgatgtggaa actgaaaaag cttctggctt gattgaagtt
     7681 atcggcgaag ctgttgatgt agaatacctt aaagaggtta aggacgtaaa catcaaccca
     7741 gccttgattg aagaatttgg taaagacatg aagattgtct acacaccact tcatggtact
     7801 ggtgaaatgt tggctcgtcg tgctcttgcc caagcaggat ttgactctgt tcaagttgtt
     7861 gaagcgcaag caactgctga cccagacttc tcaactgtaa catctccaaa cccagaaagc
     7921 caagcagcct ttgcccttgc tgaagaactt ggtcgtcaag ttggtgcaga tgttcttgtc
     7981 gcaactgacc cagacgctga ccgtgttggt gttgaagttc ttcaaaaaga tggtagctac
     8041 ctcaaccttt caggtaacca aatcggtgct atcatggcta aatacatctt ggaagctcac
     8101 aaaaacgctg gaactcttcc tgaaaatgcc gctctctgca aatctatcgt ttcaactgac
     8161 ttggtaacga agattgctga aagctacggc gcaactatgt tcaacgtctt gacaggtttc
     8221 aaatttatcg ctgaaaaaat ccaagaattc gaagaaaaac acaaccacac ttacatgatg
     8281 ggatttgaag aaagcttcgg ttacttgatt aaaccatttg tacgtgataa agatgccatc
     8341 caagccgttc ttgtcgttgc tgaacttgct gcctactacc gttctcgtgg tttgacactt
     8401 gctgacggta tcgaagaaat ctataaagaa tatggctact acgcagaaaa aacaatctct
     8461 gttactcttt caggtgtcga tggtgctgaa caaatcaaag ctattatggc taaattccgc
     8521 aacaatgctc caaaagaatg gaacgaaaca gctatcactg tcgtagaaga cttcaaggca
     8581 caaactgcta ctgttgctga cggtactgtt acaaacttga caactcctcc aagtgatgtg
     8641 ttgaaataca cacttgctga cggttcatgg attgccgttc gcccttcagg tacagaacca
     8701 aaaatcaagt tctacattgc agttgtaggg gaaaccaacg aagaatcaca agctaagatt
     8761 gctaacatcg aagcagaaat caatgcattt gtaaaataaa gacctataaa agatgagacc
     8821 aaccaacctc atcttttttc gtatcaaatc taagcaattt tagaaacttt atggcatact
     8881 agacttatca atgaaagcga ggtaatctca tggaacaatt tttagataac atcaaagacc
     8941 ttgaagtcac tacagttgtg cgtgcgcaag aagctcttga taaaaaagaa actgcaacct
     9001 tctttatcgg tcgcaaaact tgcccttact gccgtaaatt tgcaggtaca ttgtcaggtg
     9061 tcgtagctga aaccaaagct cacatttact tcatcaatag tgaagaagca agccaactca
     9121 atgatttgca agcattccgc tcacgctatg gaatcccaac tgtaccaggt tttgttcata
     9181 ttacagatgg acaaatcaac gtccgttgcg actcttcaat gtcagcacaa gaaatcaaag
     9241 atttcgcagg attgtaaaaa atcagctaac aagtcttaaa atcacaaaaa cgcataatgt
     9301 aaggtgcaaa aaccttgata ttatgcgttt tattgttcct aaaacagtta catcagcatt
     9361 tcattacaga acattttaat tttggaagtc aaatcaattt ttaacaatgt tttagaaatc
     9421 acagtgggct attccatatt caattatcca gattcaatcg ctattatcgt tttcctagat
     9481 tacaaaaaag actacgtttt gctaatcaaa acgcagtctc agccactatt ttatcttact
     9541 gtccttcttt tacttctttg gttgctacat cttctccaaa ccatttttgg ctgatttctt
     9601 ggaacttgcc gtccttgtaa agactagaaa aagcttcatt tatcttctta accaagtttg
     9661 tatcttcctt acgggctcca accgcaaaag cttctgtttc tagtccaact gtaaagacat
     9721 tataatcgtt taaaacacct tctgcttcta aataatagtt tgcatagaca cggtcaatca
     9781 atagaccatc aattcgatcg tttttcaaat caatcaaggc ttcattaaag gtttggtatt
     9841 gattcgcttc cttattagcg acaatattct tcaaaagttc tggatttgct tcaaagtccg
     9901 cataaccaga tgaaccagct tgagctccta atgtctttcc agtcatatcc tttgcagtcg
     9961 tgataccaga taatttcttc gtaaccaata cttgctcatt cttcatatat gagttactga
    10021 aagccacctt ttcacggcgt tcgtctgtag cggaatagcc attccaaatc agatcaatcg
    10081 ttccttttgt caattcagct tctttcaaat cccaatcaat cggttgccaa tttaccgtga
    10141 ttccgtattt ttcaaaaaca gctgtagcta aatcaatatc aaatcctgca taagaaccat
    10201 ctttctgagc aaatcccatt ggaacaaaag tactatcaaa tccaatagta atagacttgt
    10261 tagactggta ctttgaccaa ttatctccac tagtttcgct agaatttttc ccacaagcta
    10321 ctaagaacaa agcagtcatc agactgacta atacaagcat ccattttttc atccattttt
    10381 cctcctattt aggttctact ttcaataata catctgcgat attttcagca aactgcaaat
    10441 catgggtaac cacaatctgg gtcatcccaa gttccctatt ttgcaagatt agcttctcca
    10501 cttccaaacg taattctgga tccagggcag aagttggttc atcgtagcca atgatttctg
    10561 ggtcaatcat catagcacgc gccaaagcca cccgctgctt ttgcccacca gatagtgaga
    10621 aaggataggc ctctgcgtgt cctcctagtc ctaactgttc caagagtcca ctcgccttct
    10681 tctcagcctc ttcctgcttc attcccatgg tcttcacagg cgataaagtc aaattttcca
    10741 gaactgatag atgaggaaat agttgaaaat cttggaagac aaatcccagt aggttgcgct
    10801 tctgcaattc atccagctct aaaggttgtc cattataaaa gatttgccct gaatcaatgg
    10861 tttcaagacc cgcaagcata cgtaaaagag tcgtcttacc tccaccagaa ggtccaacga
    10921 tagccaggat ttgcttttca ggaatactta gactgaaatt agacaggatt tgtttgtctc
    10981 caaagacttt attgatattt cgtaattcta acatggcagc ctcctatcta taataactat
    11041 acttcttctc aacttttttg gaaataattg tcacaatccc aatcaaaatc aaataaatgg
    11101 ctcctgccaa gaacatagga actagactag catcgcggtt agcagctgtt cgactagcca
    11161 agataaggtc tgaaattccg agagcataga ccaaagaagt atccttgacc aaactcataa
    11221 cttcattaaa gacactagga agaacgatct tggtcacttg gggcaagata atatagcgca
    11281 ctctgtcaaa agggctaaac ttcaagacct tggcagcctc atactgtcct cttggaatag
    11341 tgtcaattcc cccacggaaa atttctgcaa agtaagctgc atagttgaga acaaaggcaa
    11401 taatagctgc aggaaggcgg tctaaacgaa tcccaatact tgggagcaca taatagataa
    11461 aaatcagttg caagagtaag ggggttcctc gcataaccca gatgtaaatg ttaatcagat
    11521 aatggagggg cttccaatgg acttgcaagg taaaagcaat caaaacgccc aacggaatcg
    11581 aaaatagcaa gaccagtgca aagacctgta cagtcgtgct cgcaccattc agtaaactcg
    11641 gtaatatctc aaataaataa gacatactgc acctcctaaa agtaattgtt cctattatag
    11701 catgaataaa caagattacc aagtattttt gtaaaaagat tctaccatat acaaataaaa
    11761 accgtagcta tcaaaagaga taaactacag ttctatatgt ttaaacattc ttacaatctc
    11821 tcaaacagtt cttgcatttg cacatcatct ggaaccagtt ttaagtaagt gtgagcatgg
    11881 acttttgctt cttcaaaatg tcccaattca cgcaagagat agatatagtg ttccagaaac
    11941 tctggattgt ccttcaaacc tcctgtcaac tcttgataat gctcataagc agtatccaaa
    12001 tcgtccattt cttgataaga acgagcaatc atccacttgg tcaaaagatt ttctggctcc
    12061 tcactctgca agtctagaat atcctcataa cgctcctgat ccatataaat agtggctaaa
    12121 cgaagcaaga tttcttctgt atcctcagcg tcttcttttg cagcaagaag ataattttct
    12181 gcaccactag catcatgcaa ttcataagaa aattgtgaag cagctagcaa gaggcgagtt
    12241 tcaaagggat ttttctctaa tccttgctta gcgatacgca gggcttcttg aacttgatgt
    12301 tccttatgta aagcctgact atacccatac tcatagcctt caaagtcagg agaaatggca
    12361 tcaagctgct taaagtagag ggtggctttt tgatattctt cttgatcaaa ataaagactg
    12421 gccaactcaa aagctgttaa gtcatcgtat tctaactcca gggctttttc taaaaactca
    12481 gtagccgttt caaatttccc taactgagca taggcaaagc caattcgttg ataggtggaa
    12541 atgcccgttt gctcataaat cgagcgatta tctaactggg cataggcttg aatagccgct
    12601 tggtaatttt ccaactcact atccaactct gccaaaccca atatcaagag agaatcctct
    12661 gagtaggtca aggcctccaa taatttctca cgtgccacat ctgtcaaacc ttccagctgg
    12721 taaaggtctg ccttcaaaac caaagacgag acataccagt cactgtcagc ttggatttcc
    12781 tcaagatagg taaaggcttc ttctatttga ccatcctcgc tagcaattgc agctagatta
    12841 agatgaacct ctggaaaatc ctctacaatt ttcaggtaaa tttccttggc ctgaggatag
    12901 aaaccaatcc cttcaagata agttgccaac tcatacagaa gatcacttga atcattttct
    12961 aaagctttgg cgaaataata ctcagcctta gttaaatctt gctcctccaa agcctgtaac
    13021 atctgttgac tattgttcac tcttgacttc ctcaccctct aattcatata gaccactgac
    13081 taccttatac cattcgaaaa tggctgaaat gacaacctta gcagaggcat aaaccggaat
    13141 accaagtaaa actccccaga taccaaacat agatcctgaa gttaacaaaa caaagagaac
    13201 attaataggg tggatgttta attgacttcc caaaatcaat ggagagacaa aacggccttc
    13261 aatagtttgt tctacgataa agacaatcac tactttcaaa agcatgactg gaccagcaat
    13321 caaacccaat actagggcag gaagcatggc tagaaagcta ccaagataag ggaccagatt
    13381 taaaatacca gcagtaaccc ccagcgtaac cgcatagcgt agaccaataa tcttgaagaa
    13441 aatgataaac attactgcta caataatagc cactgtcact tgccctcgaa catagttgga
    13501 caactgttga ttcacatctg atagaacttg tccaacaggt tccttcaatt ttcttggaat
    13561 gaattgggtc aaataattac gcaagccttt cccatcacgc aagagataaa agagcatgaa
    13621 aggaacgata atcaaggcaa caatcacttg agaagccccg ctaataaagg cactcaccca
    13681 gttgactgcc tgagatgaaa ccttacttgc caaaactgta gcctggctag aaaaattggt
    13741 caaaacttgc tctaattgag gtctgaaatc atctggcaga tgctgggcta ccaatccatt
    13801 aacaatccta tctatatctt ctaagtaaac aggaacgttt cttgcaaagg tcaaaacctg
    13861 acgttgcaga tttggaatgg cgactgccaa gccccaaatg ataaagagag cgatgataac
    13921 aaagacaata gtgataacta taacacgatt aaccttatgc ttctccatcc aatcaacaat
    13981 aggattcaac aaataatata acaaaccaga caaaatgact ggcaacatca caactgctaa
    14041 aaagtctaaa acaggtgaaa atagaaaact aatcttactt aaaataaaaa gattcagtcc
    14101 caataataag gttactaaaa ataccgtaat tgccttgtta tctaaaaacc acttgaaaaa
    14161 ccaagatagg ctaaaatgtt tctctttttg ctccataaat acttcctttc tattgttctc
    14221 tcattatacc atttttgaaa caaaataact cttttttaaa gtgcttacat ctaattggat
    14281 atctttaatt tacttgtttt tgtgatataa tagtcttatc tttacacaga ggtatagtaa
    14341 tgaaagaaac tgtttatttt ggaacttata cacgtcgtac ttctcaaggg atttacaagg
    14401 cagactttga tacagaaact ggtcagcttt caaatctaga actttttgca gctgagccaa
    14461 gtccaaccta ccttgccttt gaccagcacc aacatttata cactgttggt agccaagacg
    14521 ataagggggg aattgcagcc tatcaaactg acgggactgt gttaaatcat gttgttgaag
    14581 aaggagctcc ccactgttat gttgctgtcg atgaaaagcg tgatttggtt tacgcagcta
    14641 actatcacaa gggacaagtc cttgtttata aacgccagga agatggtagt cttctactta
    14701 gtgatatgga tcaacacagt ggccaaggtc cacatgaaaa tcaagcttcc ccccatgttc
    14761 actatacaga tttaacacct gaccactatc tagtgacctg cgacttggga actgaccaag
    14821 tcatcaccta tgacctcgat caagaaggaa aattatctaa gctctatacc tatcacagca
    14881 agccaggagc aggctcacgc catatcattt tccataacca ctataaaatc gcttatctca
    14941 tttgtgaact caatagtact atcgaagttt taatctacga tggcgttggc gaatttgaac
    15001 gtatgcaggt catttcaact ttaccggaag cttacgaagg ctttaatgga accgctgcta
    15061 ttcatctctc taaagacggt aaatacctct acgcttctaa ccgtggccat gattctatcg
    15121 cagtatatac catccttgcg gacggtagct tagagttatt agaaatcgtt ccaacgcatg
    15181 gtcagactcc acgtgatttt gatttggcac ccgaccaaaa atttctcatt gttgtccatc
    15241 aagactctga caatgcaact gtctttaaac gtaattgtga caatggtcgt ctagcagaac
    15301 tctccaacga cttccatgtt cccgaagcag tctgcatccg ttttgctcct taaaacacca
    15361 taaaaaatga acttggtatt ttcaagttca ttttttctta tagtctattt ccgacattaa
    15421 tacggttaat agcacgttgc aaagcaatct tagcacgacg ttcttggtca atcaaatgtt
    15481 tgtcttgtgc ttcttcaatt gcacgttctg cacgaagttt ggcacgttct gcacgactga
    15541 tatcgatatc acgagcacgt tctgcagagt cagcgacgat tgtgatcata tcattggcaa
    15601 tttcaataac gccaccgttt actgcaatcc agttcacgtg atctttatca tcgatacgtt
    15661 ttacctttac ttcatcaact gctaaaaccg caatcatatt ttcatgtcgt ggcaagatcc
    15721 ccatctcacc atccagagtt cgaaccgata catagctggc atggtgatca tagacgagac
    15781 catctggtgt cacgatctgg acagttaact gagccataga tcacctctta aaatcccatt
    15841 ttttcagctt ttgcaatcac atcttcgata gaacctacac cacggaaggc atcttctggc
    15901 aagtggtcgt atttaccatc aaggatttcc ttaaagccac gtacagtttc agcaactgga
    15961 acataagaac ctggctgacc agtaaattgt tccgcaacgt tgaagttttg tgacaagaag
    16021 aactggatac gacgggcgcg agcaaccaag gtcttttctt catcagaaag ttcatccata
    16081 ccaaggatag caatgatatc ttgcaattca tggtaacgtt gaaggacacg ttttacttca
    16141 gcagcaactg catagtgctc ttctccaacg atttcaggtg ccaaggcacg tgagcttgaa
    16201 gcaagtgggt caacggctgg gtagataccc aattgtacca acttacgttc caagtttgtt
    16261 gttgaatcca agtgagcgaa ggctgttgct ggcgctgggt cagtatagtc atccgctggt
    16321 acatagatag cctggataga ggttacagaa cccttcttgg ttgatgtgat acgttcttgc
    16381 aattgaccca tttccgtagc aagtgttggt tggtaaccaa cggctgatgg catacgaccc
    16441 aaaagggcag atacttctga accagcctga gtgaaacgga agatattatc gataaagaga
    16501 agcacgtctt ggccttccac atcacggaag tattcagcga ttgtcaaacc agtaagggca
    16561 acacgcatac gtgctcctgg tggctcattc atctgaccaa agaccatggc tgttttctcg
    16621 ataacgcctg attctttcat ttcccagtaa aggtcattcc cctcacgagt acgttcccca
    16681 acaccagcaa atactgaaat accaccgtgc tcttgggcaa tgttgtgaat caattcttgg
    16741 attaagacgg ttttaccaac cccggcacca ccgaaaagtc caactttacc acctttaagg
    16801 taaggggcaa gaaggtcaat aaccttgatc cctgtttcaa ggatttcaga agaggtagac
    16861 aactcatcaa aagttggagc ttttttatga attggctgac gctctgcgtc ttctgtaaaa
    16921 ggagcttcca agtcaatggt atctcccaaa acgttgaaga cacgtcccaa agtttcttta
    16981 cctactggta cagagattgg acgacctgtg tccaatactt ccattccacg agtcaaccca
    17041 tctgttgatt ccatggcgat agtacgaacc ataccatctc ctaactccaa ggctacttca
    17101 aggacgattt ttgtttttct ttcgtcattt ttgtagacga caagtgcatt gttaatctca
    17161 ggaagttttt cccctgctgc aaacaaaacg tctacaacgg gaccgataac ctgagcaatt
    17221 ttacctgaac tcatctcctt ctcctattct atataagata ctgtcggttc ctagctcaac
    17281 taggtcctaa gttcattttc atacgagctg gactagagcc tattctaagg cactagcacc
    17341 tgctacgatt tctgtaattt cttgtgtaat cgccgcctgt ctggcacggt tatactgaat
    17401 tgtcaaatca ttgatgactt tcttagcatt atctgtcgct gtttgcatgg ctgtcatacc
    17461 cgcagcattc tcagctgtct tggcatcgat aatggcaccg taaatcatac tttctgcaaa
    17521 ctgaggcaac aactgctcca gaatttcttc tcggctggtt tccaattcaa aagtcaagct
    17581 gtactcttca tccgcttcat ttggatccaa gtcaacaatc ggaagcattt gttccacacg
    17641 catttgactg gttagcgtat tgacatggtg gttgtagcaa acataaagct catcaaagag
    17701 ttcattttgg tacatttcaa cagtttttga aataatctta cgaacttgat caaagctagg
    17761 ttggtctgcc aagccacgta attcataaag tggttgaata ccgcgagcct taaagaaatc
    17821 agctcccatc ccaccgatac agatcatttc aaaaccttta ccgtctgggt gatattcttc
    17881 tttcaactcc ataacagctt tcaaaataga ggaattataa cctccaacca aaccgcggtc
    17941 tgaagtgata acgatatagc ctgtcttctt cacagaacgg ctaatcaaca tcggattagt
    18001 tgaagcacca gctccattac catgaaggat atctgtcaaa agtttacgca ctttctgagc
    18061 gtaaacttgg aagttgcgag cagcttcttc agagcgacct aacttagcag ccgataccat
    18121 ttgcatagca ttagtgattt gactcgtatt ttttgttgag gcgatttttg ttttaatatc
    18181 atttagagac actgccatct gacacctcta ttcttattgg aagctagatt gattgagaaa
    18241 ctctgtaatc gcagcatcca agactgcttc ttctggcaag tcttttgtat cacgaatggt
    18301 ttccaaaatc tctggatgtt gagcatcaaa gaaggcatgg aactcttcct cgaaacgaac
    18361 aatatcatct actggaacag tatccaagaa accatgtgtc aaagcataaa gaatggttac
    18421 ttgtttctca acaggtaatg gtttgtgaac aggttgtttc aagacctcaa cggtacgacg
    18481 tccacggttc aacttagcct gtgttgctgc gtccaagtca gaaccaaact tagtaaaggc
    18541 ttccaactca cggtatgaag caaggtcgat acgaagtgta ccagcaacct tcttcatggc
    18601 tttgatttgt gcagaaccac ctacacgaga tacagatgaa cccgcatcga tggctggacg
    18661 aatacctgca ttgaagaggc catcgccaag gaagatttgt ccatcagtga tagaaatcac
    18721 gttggttgcg atataggctg agatatctcc tgcttgtgtc tcgataaatg gtagggctgt
    18781 aattgatcca ccaccaagtt catcagaaac tttagctgag cgctcaagca aacggctgtg
    18841 gagatagaaa acatcccctg ggaaggcttc acgacctgga ggacgacgaa gcaagagcga
    18901 tagttcacga taagctaccg cttgttttga tagatcatcg tatacaatca aaacatgctt
    18961 accttgatac ataaattctt ccgccatagc aaccccagta taaggagcta ggaagagcaa
    19021 tggagatggt tgtgaagcag aggctgtcac aacgattgtg tagtccaagg caccgtactg
    19081 acgaagtgtt tctacttgcg tacgaactgt tgattctttt tgtccaatcg cgacgtagat
    19141 acagatcata tcttgatctt tttggttcaa gattgtatca atcgcaatgg ttgttttccc
    19201 tgtctgacgg tcaccgataa tcaactcacg ttgaccacga ccaatcggta caagggcgtc
    19261 aatagctttc aaaccagttt gcaatggttc tgaaacagac ttacgttgca taacaccagg
    19321 agctggtgct tctactggac gagttttatc agtgtggatt tctccaagac cgtcaactgg
    19381 acgaccaagc ggatccacaa cacgaccaat cagactttca cctacaggga cttccatgat
    19441 tttccctgta cggcggattg tatcgccttc acggatatct gtaaagtcac ctaggatgat
    19501 aataccaacg tctgttgact ccaagttttg agccatacca taagagccgt tttcaaaatt
    19561 caacaactct ccactcatga cattttcaag gccatgagca cgcgcgatac cgtccccgat
    19621 ataggttaca acacctgttt cagtcacatc aaaattgggt ttgaaatttt caatttgttg
    19681 cttaattaaa gcgctgattt cttgtgcgtt aattgccaaa agaacaccac tttctatttc
    19741 aaattttctt taacaacttt aagttgttgt ttaatactca catcaattgt cttgtgattg
    19801 gcaaaaatga caaaaccacc aatgagactt tcatcgattt gttcttttac actccttact
    19861 ttcagagaca tttttttctc aatcaaaggg agcaaacgag tcttctgttc atcagttaga
    19921 ggatgagcag acgtaatcgt cacttcaaat cgatttgttt ctttttcaag tcggttcaag
    19981 caatctacaa gcacatcata aaaaagattt gctctgtgat tgtaggccag aacctggata
    20041 aagttttgta ataaaggcga cacagaatct tggaaaaaag caattgtttt ttccttatcc
    20101 gactcgtcta ctgccacttg ttttaaaaaa gaaggcagac ctgttttttc aacaacttgc
    20161 ttgatttgag tcaagtctga aaagatacgg tcttcttctc ctttttcaag taccaattgg
    20221 acaaaaggca tgctgtattt ttcaattacc tttactgttt tcttgtccat taagcttctc
    20281 ctagctgatc gatatactga tcaatgagtg ctttatgggc atgactgtca aggttttgtg
    20341 agatgatttt accagctaag cttatggtca aatctgcgac ctcaccctta acactctgta
    20401 aagcttctac tttattttga gcaatttctt gattggcttt ttcttttaag tgtcctgctt
    20461 ctagtttagc atctgctaag atattagcct tactttgctc agctgtttcc tttgcatttt
    20521 caatgattgt cttagcttct ttacggctac cagccaattc atcttcgcgt ttttgagcca
    20581 atacttctgc tttttgacgg gcttcttcag ctctgtcaat atctgaagca attttttcag
    20641 ctctttcttc gaaaatgcct gtaatattag accatgcaaa ttttttaatc aagactagca
    20701 aaagaataaa agagccagtg attaaaacaa aattaccaat taattcacct actgttacgt
    20761 gcatcagtta ctcctttcta ttcctcttca atattaatct tattccctaa atacacagat
    20821 gtcaaaagag taaaaacata agcttggatg caggaaataa agacagaaaa tgcagtccaa
    20881 gccaaattag ctccaaaggc tactggatac caataaatag cttggtggga aagaagaagt
    20941 aacaaactcg tcatgacctc tcctgcaaag atattcccaa aaatccgcaa agccaaagat
    21001 aagaagtttg taaattcttc caagatattc atcggtatga caaaaacagg actcataaaa
    21061 gattttatac tttttttaaa tccacgacga cgaacgcttt ctatatgtgt caacaaaatg
    21121 acaagaaaag ataaggttaa gtcatactgt aaattagcgg ttggcgaact ccaccagtta
    21181 gtcccatcga tcgtttgaat ctttgtcatt aagccaaggt tattggcaat caccatgaaa
    21241 aggaataaac aaaggaaaaa gagtgagtaa tctttcatgt agcgcgaacc aatgttaggt
    21301 tctgtaaatc caataacaaa gtcatagaca tactcaagta cattttgctt tcctttgggt
    21361 ttcaaggtca tattgcggct tgcccaataa ataaagacaa aaataactcc cacaatcaac
    21421 aaagtcatgg ctaacatagt cagattgaag ataacaggac caatagagat gattggatta
    21481 atactttctt ccatctaaaa tcctcccttt tcttctcgtt ccatgtattt atttgataat
    21541 aaatgagaag acaagagtta caaagaaagt tccttcaata aaggcaacac ctaaaaacat
    21601 caaactacga aactcagaaa gcatatctgg ttggcgtgct actgatttaa acagtccatt
    21661 catcaataaa ccttcaccga cagatacgcc catacaggca atacataagc ctaaaaatgt
    21721 taaattcata acaaattctc ctttaaaata aaatttactt acttagtgta gtcctaaaat
    21781 ttaaatttgt caacttttaa ccgctattgg aagcgtttaa taaaaattat ttccattttg
    21841 ctaaatttca agttcaagtt agccatccag aagtcttctc tgggtgactt gtagtccaag
    21901 cattttttag gatagttgtt aatccacttt tcgatgaatg cgacttcttt gggagtcatt
    21961 ttcttggttc ccttaggtaa ccatctacga atgagcctgt tgtgattctc attagttccc
    22021 ctttcccaag aggcataggg atgtgcataa taaatgtgct cctcagaaaa tacatta
//
LOCUS       DAVDFK010000032        21648 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.32, whole genome shotgun sequence.
ACCESSION   DAVDFK010000032 DAVDFK010000000
VERSION     DAVDFK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.32"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(196..1056)
                     /locus_tag="VUR04_001522"
     CDS             complement(196..1056)
                     /locus_tag="VUR04_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET5341398.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHISLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDITKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1072..2349)
                     /locus_tag="VUR04_001523"
     CDS             complement(1072..2349)
                     /locus_tag="VUR04_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5341399.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTFSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2342..2893)
                     /locus_tag="VUR04_001524"
     CDS             complement(2342..2893)
                     /locus_tag="VUR04_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341400.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(2909..4168)
                     /locus_tag="VUR04_001525"
     CDS             complement(2909..4168)
                     /locus_tag="VUR04_001525"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET5341401.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5322..5480)
                     /locus_tag="VUR04_001526"
     CDS             complement(5322..5480)
                     /locus_tag="VUR04_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341402.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5490..6800)
                     /gene="obgE"
                     /locus_tag="VUR04_001527"
     CDS             complement(5490..6800)
                     /gene="obgE"
                     /locus_tag="VUR04_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET5341403.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(6864..6998)
                     /locus_tag="VUR04_001528"
     CDS             complement(6864..6998)
                     /locus_tag="VUR04_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET5341404.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7057..7233)
                     /locus_tag="VUR04_001529"
     CDS             complement(7057..7233)
                     /locus_tag="VUR04_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET5341405.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7264..8589)
                     /locus_tag="VUR04_001530"
     CDS             complement(7264..8589)
                     /locus_tag="VUR04_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5341406.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8605..9648)
                     /gene="cpoA"
                     /locus_tag="VUR04_001531"
     CDS             complement(8605..9648)
                     /gene="cpoA"
                     /locus_tag="VUR04_001531"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET5341407.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9763..10092)
                     /locus_tag="VUR04_001532"
     CDS             complement(9763..10092)
                     /locus_tag="VUR04_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET5341408.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10106..11215)
                     /gene="rpoD"
                     /locus_tag="VUR04_001533"
     CDS             complement(10106..11215)
                     /gene="rpoD"
                     /locus_tag="VUR04_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET5341409.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11218..12978)
                     /gene="dnaG"
                     /locus_tag="VUR04_001534"
     CDS             complement(11218..12978)
                     /gene="dnaG"
                     /locus_tag="VUR04_001534"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET5341410.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13068..13826)
                     /locus_tag="VUR04_001535"
     CDS             complement(13068..13826)
                     /locus_tag="VUR04_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341411.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13823..14689)
                     /locus_tag="VUR04_001536"
     CDS             complement(13823..14689)
                     /locus_tag="VUR04_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341412.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14758..15762)
                     /locus_tag="VUR04_001537"
     CDS             complement(14758..15762)
                     /locus_tag="VUR04_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5341413.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(15875..16092)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16175..18871)
                     /gene="ppc"
                     /locus_tag="VUR04_001538"
     CDS             complement(16175..18871)
                     /gene="ppc"
                     /locus_tag="VUR04_001538"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET5341414.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNCLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(18891..20120)
                     /locus_tag="VUR04_001539"
     CDS             complement(18891..20120)
                     /locus_tag="VUR04_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET5341415.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20276..20578)
                     /locus_tag="VUR04_001540"
                     /pseudo
     CDS             complement(20276..20578)
                     /locus_tag="VUR04_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(20683..20931)
                     /locus_tag="VUR04_001541"
     CDS             complement(20683..20931)
                     /locus_tag="VUR04_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HET5341416.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILAYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            complement(21213..>21648)
                     /locus_tag="VUR04_001542"
     CDS             complement(21213..>21648)
                     /locus_tag="VUR04_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HET5341417.1"
                     /translation="NLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEF
                     KSYIDHMLNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHY
                     DSWNDKANKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
BASE COUNT         6450 a         4860 c         3667 g         6671 t
ORIGIN      
        1 taatagtata taggaggaga gccctgaatc ctagaccctt tgttatgatg cgcttacaaa
       61 cagagttgga aaaaatctta aaagcagaaa aacgcatgat atcagcccct aacacttgat
      121 acaatgcgtt ttattatgaa aagatctact ggatttttta tcaaaataaa cttccagtag
      181 tcttttcact ttttattaat aagttccttc ttcaccttgg ctagtcaaga taacaggtcc
      241 atctttcgta atgacaaatt ggtgttcata ctgacatgac aatccaccgt caatggtctt
      301 atgcgcccaa ccagttttca tatctgtatc aatttcccaa tcgcctgtat tgatcattgg
      361 ttcaatggtt aagaccattc cttcacgaag acggagtcca cgacctgcaa taccatagtt
      421 aggaaccatt ggttcttcgt gcatagttgg gccaacacca tgaccaacca aatcacgcac
      481 tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc gcaccgatat caccgatacg
      541 atttccaaca acagcttgct caataccctt gtacatagct tctttggtta tatccatcaa
      601 gtttttgact tcttcggacg gtgtaccaac agcataagcc caacatgagt ctgctaaacc
      661 accagaatag ctctgagtgt attttttcat ttgttcaaca ttgttgaagt ttaattttga
      721 gacattcagg tcggatttag caatgggacc tcccaaaacc atatcaactt tgagcaaatc
      781 accatctttc aagatataat gacgagggaa agcgtgagcc acttcatcgt taagagagca
      841 acaggtagca taaggatagt ccatcatggc accgtcaacc ccaatctgaa gtggaaggaa
      901 attttcttct ttacaacgac ggcggacata ttcttcaact tcccacatat ctacgcctgg
      961 tttaatcaaa tcacgtaagc ttatatgaat acttgctaga aaatcaccag ccttgtccat
     1021 agcttcgatt tcacgagctg attttaatgt tatcatcttt tctcctagtt tctaattaat
     1081 tttaacagtc acatttgctt ttgaaacaat ctggtgacca tgataaatat cgtaatcaat
     1141 tatagctgac cgtctcgtat gatgaataat ccgtgcctga atgcgcaata tatcatctat
     1201 ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata atgagattgc gaccactatt
     1261 aacaactaaa tcttgggtca tgtgggtcag aatttctgcc aatacaccat tagccaaaac
     1321 tccatttttt tctagcataa agggttccac tgtaataact acttcatcat ggtgataaga
     1381 gagcttttgt ccaatctgct cagaaaaagt tggtagagcc gaaacttggg aacggctcat
     1441 cttctccatg acatctcgtc gcgtcacaac gccaagcaaa gtttgattgc ttcgaacaac
     1501 tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc acattggcaa tatttgtcga
     1561 taatccaacc aaaaatagac tacgagacat aaccttatca attgtcgtgc ttggtgattt
     1621 atcaccagcg tctctcatgg ttacaacgcc aacaacgacc tgatgttgat tgataacagg
     1681 gaaacggctg ctacgattct tacgaaccaa gtccaaataa tctttaactg tatctgtctc
     1741 tctcagaaaa ccatactcat gactagggcg ataaagtttc tcaactgtca gaatatcagt
     1801 cttgatttgg acatttgaca aggctttatt gatcatggtc gcgacggtaa aggtatcatg
     1861 cttacttctt agaacaggaa tccctttttg attggccagt ttaagcacat catcatgaac
     1921 ctgaaatccc cctgtaacca gaactgcatt ttcattttcc aaggctagca actgaatacg
     1981 ggttcggtct ccgacaatca agagcccccc atcatgaagg taagacaaga tattttgttc
     2041 agtcatggca ccaattgaaa acttactaaa ttctctctct aaaccttctt gcccagccag
     2101 aacctcagaa aaagtcactt ctgcaatttc agcaaacgtt aatctatcta tagcaacttt
     2161 ctgggattta acacgaattg ttccacttct aggacgggtc tccacaattc cacggttttc
     2221 agcttcttta atagctcgat aggctgttcc atcactaact cctagatgat tcgaaatgct
     2281 acgaacactg acccttttac ctactggtaa ttcctccaaa tagcttagaa tttcctgatg
     2341 cttactcatt gaactctcct tttacatacc gaaattcaag ataatcccgc atttttcttg
     2401 tgtaacgatc acttccctta aactgacgga acaaactaaa tccagactta agagcaactc
     2461 tttggctagc ttcattttca aggtgggtaa tgataaataa ttgttttaag ccaaattcct
     2521 caaaagaaag ctgacaaatt tttctaacaa cctctgtcat aaatccttgc gaccaagcat
     2581 cttttctcaa aaaatagcca agctcagctt cttttttgat ttcatctaac ttctcaaatt
     2641 taatagaacc aatcatttgt tgatttttct ggtcacaaat tgcccacact cccaaagggg
     2701 acttcataaa gtaattggcc agtgcatatt gactttcttc cagacttgcc tgcgttggga
     2761 aaataaattg aagattttct ggatttgaag ctatctcgcg gaagtcctga ctatcactaa
     2821 aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa agaaaacatt gctaatttgg
     2881 tccaaatatt cataaacacc tctacggttt aatcctcaac aagtctaata tccgctccta
     2941 aattacgtaa tttttcgata atatcagaat aaccacgtaa gataaactcg atattggtaa
     3001 tttcagtttt accttcagcc ataagcccag caatgactag tgcagcccca gctcttaagt
     3061 cggtcgcttt aacactggcc ccacgtaaat cacgtccacc cgtgtacaaa atatgaccat
     3121 ttgttgtcga aatatccgca tccatctttg ctagttcaaa aacatgattt acacgttttt
     3181 cgtaaatcgt atcgacaatt gtaccacgac cattcgctct tagtaaaaga ggggtaagcg
     3241 gttgttgcaa atcagttgca aagcctgggt aaggagctgt cttaatattg attgctttca
     3301 aattagactg ttcctcgaca aaaatgctgt cttcagatac agtcattctc actcccattt
     3361 cttccaactt agcaataaac ccttccaggt gttcgtaaag aacattattt atacgaattc
     3421 ctttaccaac tgcagcagcc aaagatatat atgttccagc ttcaatgcgg tctggaatca
     3481 cctgatgacg tgtcccatgt aatctttcaa caccatcaat aatgatgata ttagttcctg
     3541 ccccacggat atgggcaccc atattattca agagagtagc tacatcaata atctcaggtt
     3601 cacgggctgc attttcaata atagtacgac catttgcttt aaccgcagca atcatcgtat
     3661 taatcgttgc tcccacacta accgtatcca tgtaaatact tgcaccatga agtcctgtat
     3721 ctttagcaga taacttcatg ttatctccct cgtagctagc agtggcaccc atagcttcaa
     3781 acgccttaag gtgtaagtca atcggacgag gaccaagatc acatcctccc ggtagaccaa
     3841 ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa atagtaagat gcacgaagac
     3901 tgttaatttt accataaggc attggaatat tttgaacacc tcttggatca atctccaaga
     3961 catcgtcata acgcttaaca gtagctccca ttaattccat gatttcgaca agactggcta
     4021 catccgaaat atctggaaca caatccaaag tcaccacatc atcagccaat ataatagctg
     4081 gaattaaggc cacaacacta tttttagcac cactaatagt aatttcacct tgcagtggta
     4141 atccaccatt gataacaatt tttctcattc taagttttca atactctttc aagatttcta
     4201 ataaggtctt caaaataaag tatatcataa atttatcctt ttttccatcc ttttcaattt
     4261 tattggataa atcatagttg acgagttagt aactgaatta ctaatactca atgaaaatca
     4321 aagatcaaac taggaaacta accgcaggtt gctcaaaaca ctgttttgag attgtagatg
     4381 gaactgacgt agtcagtatc ctacacatac ggcaaggcga tattgacgtg atttgaagag
     4441 attttcgaag agtataatct ttctcgaatc gctattgccc cttttttatc ccctaaaact
     4501 gagtaggagc taagactaga tctcttatct aagtatcgga atacggctgt tcaactaaat
     4561 tttagcaaga acttctcccc ttctctcagt tcacagaagc gttttataca taccgtccta
     4621 tcagacaatc tattttaaag ataaccgtga ctcaggatca cttctatctg tcgttttctc
     4681 tttatagtga tagacctcac gggataaatc gtacatcttt cctcgtgtat acaagatata
     4741 aggacgttaa aaggttacag tgaaaataga aaatcttagt acgaattcaa ttactctcgt
     4801 gatttacgca tataggttac gactaccttt ttggacttta gagtttgagg ccctcttatc
     4861 cgctatatac gccttattat cacgttcctg ttcgtagagc cacgatttcg ctatcccttc
     4921 ttctgacaat tcttatttcc agcgtcagac ttaaaacggt ctatccccag accattttaa
     4981 tccgctacct cacgatagtc aggcttggga atcgctattt gactcgccga gaactttgac
     5041 atcagatata ctataacaaa ttgaaataag aatcaaacaa tttaattttg aaattcaaat
     5101 caatttataa caatatagtt gattgaaact agaatagtac acctctgctt ctaaaacatt
     5161 gttagaaatc gattttactg tcctgatcga tttgtcttgt tctcatttca ttttactata
     5221 ttttagaaga tatgctgtgc tattccagat tcagttcgct atacatgccc gtcgtaccac
     5281 aaaatcccgt gtctgatgag gcacgggatt ttttagcttc tttactgaga tggattttcc
     5341 tttttagttc gtgctaatct caaggcacga tttggattga gacgattaaa tagttcttcc
     5401 aatttctttt cattccaaac gtctgcggcg gaaacaaaat taccatccgc atctcggaaa
     5461 gatatcggtt tatctcccat accagtctcc tagtctacaa attcaaactc aaatttacca
     5521 atgcggacca aatccccatc tttagctcca cgcgcacgaa gggcttcatc aacccccata
     5581 ccacgaagct gacgggcaaa tttcatgaca gattcatcac gatcaaagtt ggtcatatta
     5641 aagagtttca tgagtttttc accagaaagt acccatgtcg catcgtcatc acgactaatt
     5701 tcaaaggctt tttcttcttc gtcaaatcca tagtaagctt cttcttccat atcggactcg
     5761 tcgtagagca aaaattctgg tgtcttgtct aacaattcag ctgtagcatc taaaagtgtt
     5821 gccagacctt gcttggtcaa tccagaaatt gggaagatag ctggtaactc ttcaaattca
     5881 tcataatttt cagacaattt tttcttaaat tcttcaagat tttcctgact ctcaggcatg
     5941 tccatcttat tagctacaat aatctgtgga cgctccatga ggcgaagatt gtaagactcc
     6001 agctctttat tgatagctag gtaatcctca tatggatcac ggccttcgct agctgacata
     6061 tcaatgatgt gaaggataac acgtgtacgc tcgatgtgac ggagaaactg agttcccaaa
     6121 ccaacacctt gactagcccc ttcaatcaaa cctggcaagt cggctactgc aaaggattca
     6181 cctgattggg tgcgaaccat acctaaattt ggtacaatag tggtaaagtg gtaggcacca
     6241 attttaggct tagctgaggt aataacactt aaaagtgttg acttccctac agatgggaat
     6301 cctactaaac cgacatctgc caagattttt agttccaatt gtaactcacg ttcctgacct
     6361 ggttctccat tttcagagat ttccggtgca ggattttttg gtgtcgcgaa acgaatattt
     6421 ccacgtccac cacgaccacc gtgggcaacg ataaattctt gcccatgttc aatcaaatct
     6481 gttaaaacct tgccagtctc cgcatcacga acagtcgtac cttgtggtac tcgaactcta
     6541 aggtcctcag caccacgacc atgcatccct ttggtcatcc ctttttcacc agaatcagcc
     6601 ttgaaatgac gattgtagcg gaaatccatc aaggtacgta gtccttcgtc tacaacgaag
     6661 accacattgc ctccacgacc accatcacca ccccaagggc ctccattagg gacatatttt
     6721 tcacgacgaa aggcaaccat accatcgcca ccattaccag ccttgacctt aatcttagct
     6781 gtatctaaaa acatactcat tatttcttct cactttaaaa aagggctggg aaatcccagt
     6841 cactaaattt tcttgaatct attttataga ttactgaggg caccaattgc agttgcaaaa
     6901 attcccaata aacttgctac tagcatgata atcacgataa acaaggttat tttctcaaac
     6961 atagtttttt tacgatttcc attatctcca aatgccattt ttctctcctt cgttacattc
     7021 tattttctat tatcttagca tgaattgagc tagttttcaa tagtcagttg ctactggtgc
     7081 gataatccat aaaataatat aagctacaat tccagctccg taacagcaag taagaacacc
     7141 ccaaatgact tgaacgatag tcggatccat atccagataa tgggccaccc cagcacaaac
     7201 acccgcaatc tttttatcac gaccgcttct cattaattgt ttttttcata gctgttcctc
     7261 tttctattct tcatggtctt tccaatagtc tctcatactg atcaactgtg tttttgaagc
     7321 cttcaacatg cgtctagatc cttttacagg tacagcaacc acctgttgcg gaagatacaa
     7381 aactgtccta aagatacgct gactgaccgt atcatcttta gccaaatctt tctggaagtt
     7441 atttgaaata atggcatcca gataaaactc atgcactcgt ttcccaaagt tctcagctga
     7501 aatctcatac aatttctctg ataaggtatg ctcattcatg tctggtgttg caatcagggc
     7561 ttccaaaata gcaccagcca aatcatgttc tccatagtac aaggctccaa acattttatc
     7621 actgatgagg ttgttcaaat aaggatttcc gtgagcaatg acaggtgttc cactggctaa
     7681 gctttccaag taggtcaaac cttgcgtttc gcttgtcgat gccgaaatga agaaatccgc
     7741 cgctttatag taaagagccg tctcactagg agcaatcatc cctgtaaaga tgactgagtc
     7801 ttgaatctct aggttctggg cttgctcttt gaggtcattc agataagggc catccccagc
     7861 tactaccagt ttaaccttgt cttcctcttt cagaacatca gcaaaggctg ctaaaactgc
     7921 ttgaatattt ttttcatagg agattctcga aagactaagc aacgtctttt caccatcttg
     7981 aatccctagt ttactacgca gttctttcaa attttcctgc ttgatttccg gacgctcaaa
     8041 cttggctaat tcaatcccag taggaatgac ccgtttttca accttgacct tataatcaga
     8101 tagcaagtca cggacaatct cactagggca aataacccca tccacatcat gcaggaaacc
     8161 tctaaccaga tacttgacca tactcggccg gatcaatatc cccttagcaa tataatggac
     8221 atagtcttca tactgggtgt gataggtatg gatgactgga attttcaatt cacgcgcaat
     8281 ccaaatcccc aacaggccaa gagaaaattc tgtctgagta tggataatat ctagctgata
     8341 ctgtttagca atttcaagtg ccttgctaaa acctcggtag gcaaagcgac gatccttaaa
     8401 agcaaagaaa ggaacacttg gaatgcggat aatttgccaa tcttcgtagc gattgacatc
     8461 cttatctgtc gtcgtaaaga taaaaacagc atgtccctgc ttttcaagtt ctgttttcaa
     8521 ggttcgaata ctggtcgcaa caccagaaac ctgaggaaaa taggtatctg taaataaacc
     8581 aattcgcata gattacctca ctttttactt tctccctaaa gcggcttgtt tctcataaaa
     8641 gtccaaccag atttgtaaca gatgctcttc agaatactct ctggaaatat tcttagcctt
     8701 ttctttgaga tcttttaaga cagcaggatt tgcttgatat tccaaaatag cctctttcat
     8761 ctcttctcta cccgctgtcg cccgataatt tccctccaaa atcaccttat agagatctaa
     8821 atcacgcaac ataataggag cctcacaact cgcagcttct aaaatagtca taggaaagag
     8881 ctcattgtaa ctaggcaaca agaaaagatc cgctagagca tacaattcgc gcatccgctc
     8941 tggcgataca atgcctggaa aaatcaaatt tttaggggga ttttccataa ttttcttata
     9001 gtgttcataa ccatctgtca taccaccaaa agagaagcca ccagcccaga taaaggtaat
     9061 ctgaggcaat tcctcagcca gacggataaa gtcatcaatc cctttacgtt tctgaacttg
     9121 cccagcacct actacgataa actgattgtc actaagacca agatctgtgc gcagtctgac
     9181 tacctcttct tgtggtagag gatgccattt ttccttgttg acaaagttag gaatataggt
     9241 cactttttca cgtggaatac cagctgctac caaatcctca ataaacatag gattgaccac
     9301 aaccaagtgc tccatccggt tgtaaaaaga aaatacatag cgtttcacaa ttccctttaa
     9361 gaaaaatgga attttcaaac ttccttcaag tgtagctggc aagaaatgca catagccaat
     9421 ctttctccct gagcgtttct tttggaaggt tgataaataa tagggaaaat caatcgtatg
     9481 aaagtgagtc acatctgcct cgattggaag attttctgta acaatcaatt ggtccttggc
     9541 agcacggtga agaagacgaa ctaattcacg gtaagcacct gaaactccct gtcctgctac
     9601 tttctcactt gaactcaaca tattgatgcg taatttcttt ttctccataa ctactattat
     9661 atcattttct ttgaataaaa tcagcaaaag aaaggagaga ctagaggaaa agaggggaaa
     9721 tttcctcgct tttccaacag tctctcacat gcttttatat gtttacttaa tgcctagggc
     9781 aatgcgggca tagcgactca ttttttcaac tgtccaggct ggataccaga ctaatttaac
     9841 ctcagtatcc gttacttctg gaacctctat catagcatca taaatctggt ctgtcaaaag
     9901 gtctgctaag ggacaaccca tagttgtcaa agtcatgtca atctctgttt gccctgtgtc
     9961 accgtcaaaa cgaatctcat agatcaaacc aagattgaca atatcgattc ccaactcagg
    10021 gtcgatgact tcttccaagg ctgttaaaat ccgtgttttg atgttttcaa tttgctcttc
    10081 tgtataagcc atattttcct cactcttagt cttcaataaa atcacgaagc ggtttgctgc
    10141 ggcttggttg gcgtagtttt ctcaaagcct ttgcttcaat ctgacggata cgctcacgag
    10201 ttacgttaaa gactttcccc acatcttcaa gtgtgcgcat ttttccatca tctagtccaa
    10261 aacgtagacg cagaacattt tcttcacggt ctgtaagagt atctaagatt tcatccaatt
    10321 gctcacgcaa gacgatacga gtcgtataat ccactggatt ttcaatcact tcatcttcga
    10381 taaagtctcc aaggtggcta tcgtcctctt caccgatagg agtttcaaga gatactggtt
    10441 cttgggcaat cttcaagatt tcacgaacct tatcaggtgt catatccatt cgttcagcaa
    10501 tctgttctgg tgtcggatct tgccccaatt cttgaaggag attccgctgt tcacgaacca
    10561 atttattgat agtttcaacc atgtgaactg ggatacggat ggtacgagct tgatccgcaa
    10621 tagcacgagt gatagcctga cgaatccacc aagttgcata agttgaaaac ttgaaccctt
    10681 tagaatagtc aaacttgtca accgccttca tcaagcccat atttccttct tgaatcaagt
    10741 caaggaactg catgccacga ccgacatagc gtttggcaat agaaacaacc aaacgaagat
    10801 tggcttccgc aagacgttgt ttggcttcga tatcgccagc ttcaacagcc agtgccaact
    10861 ctttctcctc ttcattggtc aagagaggaa cgacccctat ttctttcaag tacatacgga
    10921 cagggtcatt gaccttagca gaagttgacc caatcaagtc ctcatcgctg agttctggtt
    10981 cttcttcatt gctaagaaca cgcgcacttg gatttccttc gttatctgtg atagaaatgc
    11041 ctgcatcctg aatccgttgc aagagatctt caatcccatc agcgtccaag gtaaaaggaa
    11101 taaccagact tgcattgatt tcatcatctg ttgctgtccc tttttgctta tgattacgga
    11161 taaattctgc tacctgtacg tcaaatgttg ttacttcttt ttgttttgtt gccattatta
    11221 ctccattctt ctcttttggg aaattaaacg ttccaattct tctagggctg tatctgtatc
    11281 tcctacatgg ctagcttcct gcaccttctt tttgattctc atattgtcct gattcaagag
    11341 agccttgttt cgagtcatct ctacttcact aagttcctgc ggcgatatct cagcaggcaa
    11401 atcctgagct aaaacttggt accaagctct ttcaacttcc tctgtctgct ctgctaaaac
    11461 ttctggagga agatttccat actggccaag caagtcatat aagacctgaa attcaggtgt
    11521 agcaaatgca aagtcttctc gcaaacggta atcgttcaaa acaagagggg attccatcat
    11581 ccgatagagt agatgggctt ctgccctcat aatagccgat aactgcttgg tgataggcat
    11641 ggtgattggc gtcggtctgg aaattccttc catgcgattc tgcctttgca cctgacgact
    11701 ctcattaaca atctgctcaa tctgggcata atcaaaggac gccagactgt cagctaaaat
    11761 atgaatatag ctgttttgag cagcgatgga cttttcttga acaatcaagg gagctatttt
    11821 ttcaataaac tcaatctgag cctgcagatt ttcactgttt tcaggtttgt actgatgaat
    11881 gtagaactca atcggactaa tacgagtttt cgttaataga taggccaagt cttctggacc
    11941 atttttttgt agatactcat caggatccaa gttatcaggc atgctaacga tttgcacagg
    12001 catatcacca atttcatcca atgctttcaa tatcgcggct tgcccagcct tatctccatc
    12061 gtaaacaaga accaatttct tggttaacct tttcagatgc tcaacatgct ctcgactcaa
    12121 ggccgttccc atcgacgcca cagcattttc gattccagcc cgataggctg caataacatc
    12181 catgaatcct tccatcaggt aaatctcact agtttttcca gaagattttt ttgccctatc
    12241 catatgatat aattcgtaac ttttgttaaa aattgcagtc gatcggctgt ttttatactt
    12301 agaagtttgt gaatctgttt tttgccagat acgacctgag aaggcaatga cctttccttg
    12361 gtcatttgtc aggggaaaca taatgcgatt gtgaaaggtg tctacaaatt gattggcatc
    12421 cgagagataa aacaggcctg aatccagtaa atcttcttca cgatactgat cagacaaacg
    12481 ttgatagaga tagtttcgtt ctggaggtgc taaaccaatc caaaaatgtt taagcacttc
    12541 atctgtcaaa ccccgctgat aaaggtaatt tctggcctct tcgcccatag tcgttgtcat
    12601 gagaatagca tggtaaaatt tagccgcatc ttcgtgcata tcataaagag cttggtgagg
    12661 cgaggctggc ttctgttcac tataaagcgg tttttcaacc tcaatcccga cacgctgacc
    12721 taagatttgg acagcctcca taaaggtaac cccttggtac tcctcgatga atttaaagac
    12781 atcacctgag cgaccacaac caaaacagtg gtaaaactgc ttgtcctcta caacgttgaa
    12841 agaaggtgtt ttttcaccat gaaaaggaca gagccctaga tagttccgtc ctgccttttg
    12901 taaagaaatc acatctccta tgacttccac aatgttggca ttgtttttga tttcttcaat
    12961 gacttgtttg tcaaccatac acaatacctc catgttatca tagtttactt tatatagtat
    13021 actttatttc agaaaaaaag taaaccattt cactcatttt ccctacttta ttcaaagagt
    13081 tgataataat cagagatttt catttttgct ttttcttctt ggtttaaatc ttggataatc
    13141 cgtccttctt tcatgacaat caagcgattg ccgtatttga gagcatcttc catatgatga
    13201 gtaatcataa gggctgttag ctgatctttc ttaacaaatt catctgtcaa ttccatcaaa
    13261 gcaacactag tctttggatc cagggcagca gtatgctcat ctaacaggag taattcaggt
    13321 cgcttcaagg ttgccatcaa gagactcaaa gcctgtcttt gtccacctga taagaactca
    13381 atcggtgtat tcaagtgttt ctcaagacca tttcctactt tttcaatggt tgcctgaaat
    13441 tcatccttat agctagtcaa gcgtcttggt aacaatccac gcttttcacc acgaaacttg
    13501 gcgattaaaa gattttcagc gaccgtcata cggggagctg tccccatctt tggatcttgg
    13561 aagacacgag acaggtactt ggcacgcttc tcgggtgaaa acttagtgag atcttcacct
    13621 aaaatacgga tagttccact agttagtgat aaggtccctg ctatagtgtt aaagagagtt
    13681 gattttccag caccatttcc gcccaaaatc gtgataaagt cccgttcaaa aatttctaag
    13741 gaaacatcat ttaaaataat cttttcttca tcaaagccat ttttaacgat tttggttgca
    13801 ttttttaatt ctacaattgc tgtcatttgc ttaacttggc tcctttcaag attgtttgct
    13861 taaatgttgg aatcatgagg cagactgcta aaatcaaggc actgtataaa cgaaggtaac
    13921 ttgtattaaa gccaagtgcg ataactgccc acactaaaaa ttgataagcg atagaaccta
    13981 caacgatagt aaccaaacgc tctgccaagc tcaaactctt gaaaataact tctccaataa
    14041 tcaaacttgc aagccccaca acgataaccc cgatccctcg agacacatcg gcatagcctt
    14101 cttgctgagc aatgagggca cctgcaaggg caatcacacc atttgataag accaagccca
    14161 tgagctccat gcgtccagta tgaatcccga aacttctagc catatcagga ttatcccctg
    14221 tagcaatata ggcttgtccg agtttagtgt ccaagaaaaa gagcatgaga gcaataacaa
    14281 tactcacaaa gatgagacct gtcaagagtt gattcaaatc cgaatcaaaa ggcaaaacat
    14341 cctgaatttg cttggttcca agcaggccta aattcgcacg tcccataatc aagagcatga
    14401 ttgagtgaca agaagtcatc accaaaatcc ctgagagcaa ggttgggatc ttcccttttg
    14461 tataaagaag gcctgctgcc attccagcca aacaacctgc tcctacagca acaagtgtcg
    14521 ctaaaaatgg gttcacgcct ttggttatca aagtgacagc aacagctccc ccaagaggga
    14581 aggaaccttc tgtcgtcata tctggaaagt ttaaaatcct aaatgtcata aagattccca
    14641 gacctagaat agcccagaca aatccttgag aaataatgga aacaatcata ttttatttaa
    14701 tcctttctat attcatcttt ttaaaaaatg ggaagagtct cctcctccct accttattta
    14761 ttcgatgact tgtcctgctt ctttgagaac agactcagga atagtaatac ctagttcttg
    14821 tgctattttt ttattgatga ctgacttacc agttgaaaag acattgactg gggtatcggc
    14881 tggttttgca cctttcaaga cttgcacaat cattttacct gttgccacac caaggtcatg
    14941 ttggtcaatt acaactgatg ccaaaccacc tacttctacc atagctgtcg cactgggata
    15001 aattggtttc ttagaacttt gattgctaga gacaaccgtt ggaaatcctg atgcaatggt
    15061 gttatcaatt ggaacccaaa tagcatctac cttgctagtc ataacagtga cagttgaggc
    15121 aatttcattt gttgaaggaa ctgcaaatgt ttccactgtc agacctgctt tttcagcata
    15181 agccttaaat tcttcgacct gtgtttttga attgtcttcg ctacttgagt aaagagctcc
    15241 gattgttttc acattcggtg tcagagcctt gatgagttca acttgttgtt gagctggatt
    15301 gtggtcagat acccctgtaa cgttgccacc tggttttttc aaatctttaa ccaagttagc
    15361 accaattggg tctgtaatag cggccatgat aaccggtagg tcttttgttg cactagccaa
    15421 cccttgggct gctggtgttg cgataccaac cacaaggtca ttcccatttg caaccaattg
    15481 tttactcatt gtcgcaacct tactttggtc accttctgag ttcataaaat caattttaac
    15541 ttgatcatct ttatatcctt cttctgcaag tccatcttgg atccctttat aaatcaaatc
    15601 aagggatgga tggctcacaa attgaagcac accaatcttg gttattttct tctcatcctt
    15661 attattctga acttctgatt tattcattga agaataaatc aagcttcctg ctactaagac
    15721 tgctaatgca gcaataattc caattaaacg tttatttttc attctgtttc tcctttttat
    15781 ttcctttaac atatttcact tatctaaaca agcgacgcca tcgttttctt tccatactaa
    15841 cctccatcaa aaaaatcctc acacaaaaaa cttgtgtgag gacgtcgatg cgcggtacca
    15901 cctcaattat aggaaatttc cctatcgctc agtctcgcaa taacgagatg cactgtaagg
    15961 tgtgcttacc gaatttttat aatttcaaat tctaaatagc attcagccca attttcatca
    16021 tcgccactta tctgttttca gctaccacag actctctaaa aagtttgtat gattactttt
    16081 ctgaatggtt aaattatatc atttttaaac tacttgtcaa tagtctatta gaattttttt
    16141 gatattcact tttagcattc actcttgaaa attatcaacc tgaattacgc aatcctgtcg
    16201 caattccgtt gatcgtgata tgaatcaatc gttcttgatc actggacaat tctccacgac
    16261 gttggcgttt aatcaactcc aactgaatat agttgagaat attaaagtaa ggcatacggt
    16321 aatccagact agcttttaga tatggattgt cagctaagag ttcgtcatgt ccttcaatag
    16381 ccaagataac gttcttagta acttgccatt catttaaaat agtctcatag atggccttaa
    16441 cttgctcgtc ttcacaaagt ttagcatatt caaaagcaat attcatattt gattttgaca
    16501 aaaccatatc aacatttgaa agaagcgatt ggaagaaagg ccaattttgg tacatatctc
    16561 gtaagatagc aatattctct ggatttttat tgataaattc cttgaagctt gaaccaaccc
    16621 cgtaccatcc agggaacata acacgactct gtgaccatga gaatacccaa gggatggcac
    16681 gcaaaccacc gatttcagta atagtcttac gagcggctgg acgagaacca atattaaaac
    16741 ttgaaatagc cttgattgga cttgactcga agaaataatc atagaaatgc tcattaccaa
    16801 agaccaaatc acggtagata tcgtaactac ggtccactac ttgatccata atggcttcat
    16861 aacgatttgg ggtattggta tcgctcttct tctgagtaat catacggtta atagctgccg
    16921 atactagcat ttcaaggtta tagtaagcgg cgtctttgtt accgtattta ttcccaatta
    16981 cttcaccctg ctccgtcaaa cggatacgat ccttgataga cttgagcggt tgagatgtaa
    17041 tggcttcata ggttggccca ccaccacgac cgacagtacc accacgacca tggaagaagg
    17101 taaccttaac gccaaattca tctccaatag cagtcaattg ttgttgagcc ttgtagaggg
    17161 tccaacatga tgacaagtaa ccgccatctt tattactgtc agagtagcca agcatgattt
    17221 cttggtagtt atttcgtgag tcaatccatt ttttggcaag gctaagagaa agatattttc
    17281 tcattgtttc ctctgaatga tccaagtctt caattgtttc aaaaagggga acaatctgaa
    17341 cacgcgccct ttccgtatcc accagtccta cttcttttaa cagaatagct aattctagca
    17401 tatcagaaag gctggttgca tgtgaaatga tggtctgacg gatgacatca tctcccaact
    17461 tatctttcaa aacacgagcc gtcttaaaaa tagctaattc ttttgctaat aattctgatt
    17521 tttctgcgtg agtcgcagaa agaattcggg gatcttcttc taattctttc aagagaaggt
    17581 cacacttttc ttcttcgctc aactcgctat aacgagaatg aattcctgct gatttcaaga
    17641 gttctgccac acaggcttca tagacgctag agtcttgtcg catatcaatt gatgctaagt
    17701 aaaaaccaaa tatctctact gcctgcaata attccacaaa atcacctgaa atcaaggact
    17761 cgcccttatt ttctagtaga gaatctcgaa tggcaatcaa atccttgtag aaatcattgg
    17821 cggtttcata acgagtccca acttcttcat cctcaatcag ataggtttta gttgcctgaa
    17881 tttttgattg aatatcaaac aaggcacgac ggtaaagctc tttttcgcgg taaatcgagt
    17941 tatccttgga ttgacgagcc atttctctga cttgcttgct gacgttgaca atgctagttg
    18001 aaagagaaaa ttcacgataa agttggtaaa tctttttatc atagtagttc atgatgactt
    18061 cacactgagt gagtgcagac tgcttcaagg tctttgctgt aacaaatgga tttccatcac
    18121 ggtcaccacc tatccacata cccatggtga ttggtttagc ctgttttaaa ttcagaccat
    18181 gcgcttgcgc taagcgctta tactccgtcg tcaaatgagg tacagctttc aaaaaggagc
    18241 tgttataata ttccatagca ttcgtgattt cgttagtcac ttttaatttt ttctcacgaa
    18301 tcatgtctgt ctgcatgata atttcgatgt aacgacgcaa atcattgtac catttatctt
    18361 tattgatcaa ccccaactta acatcacggt atttacgcaa aagactatga atatgatttg
    18421 ttaaatccaa catacttttg cgttgcactt gtgttggatg ggctgtcaaa acagggacaa
    18481 cattcaagtg ttctaggatc tcaacggcat tttccttttc tgctaccaat ttaatcgttg
    18541 tagataattt acctaaatag tcctgatcaa tattattttg atgattgatt tcataagcta
    18601 aatccacatc ctctgaaata ttaatcaaaa gaggtaagat agagaaatag cgtgaaatat
    18661 agaccatttc atcatttgat aagctagtca ctagacagtt tagaccttga taatcttcct
    18721 gcgttgataa ttctttcaac tgtattattt tttcaaaggt ctctggggca agcatatttt
    18781 tagtaatatc ttccagtaat tctgttagaa tcaagacttc ttcttgcaca acacttttat
    18841 tactataatt ttctaatttt tgaagagaca taaactatcc tttctttatc ctacttcaac
    18901 agaaggttca ttggttgatt ttccaattct cggtacaact tagcgcgttt ttcactggca
    18961 tcaatattta agacaaaggc tactgccact gataagacta gaagactatt tccaccctgg
    19021 gataagaaag ggaaagtcac tcctgtagat ggaatcaagc ccgaaatccc tccgatattg
    19081 acaaatacct gaaccaacat catccctccg acaccgagtg caaccatggc attgaaagga
    19141 ttctccgctc ggataccgac caagataatc cgcaaaatca tgaaaaacaa gagagctaaa
    19201 ataagactgg caccaacaaa gccaaattct tcaatcacga tagaaaagac aaagtctgta
    19261 tgagcttctg gcaaataacc tcgtttttca atcgagtttc caagacctag accaaaccaa
    19321 ccaccattga ccatggcaaa ataagaatta gctaactggt gacctgcatc agcacgatcg
    19381 gcaaaaggat taaaaaaggc actaaagcgc ttggctacat agccaaatac tggaattttt
    19441 gaaaaggtct caacaccgat taggctgata gtggtcaaga caaagacaga agtggcagat
    19501 acgagcgcca gaatggttga aaaccagcga taagcgattc cactaactgt atacataatc
    19561 aaggaaacca agactaaaat agtcgcattt cctaaatcag ggaaaattcc caaacttcca
    19621 atcagaacta ggagaacgaa tcgccaatca ttaaaagcac ggggaagcca ttgattttga
    19681 gtcaaaactt gaaaatcata agtagctatt tcttcttgct gtttggagaa tcggtgagct
    19741 aaataccaaa taataatgat ttttaagtac tcagctggct gaatagttac tcctgcaacc
    19801 gaaatccaac cgtatgcccc gtttactgaa ataccaataa aacgagccaa gaacaataaa
    19861 agcatttcta ttaatataac taaaatgatt agtcgctcat ttctcaaaaa atctagtctc
    19921 aatttataaa ttaaggcaat cagtatcaaa ctaacaatcc aaaagattcc ttggtttcga
    19981 accaactgca aggcgctctt gccttcttca attaaaatag cactggtggt cgaatagacc
    20041 acaatcaagc ccaaaataga taaaagcaag tagggaatca agatggaata atttaataag
    20101 tgcctcttac taatcttcat agtatcacca ctctactagg atacagacaa atctgttcca
    20161 aattccgttt tattttctag ttttgattgc tattatacca ttttttcaga aagaaaaaaa
    20221 ctcttacctt acaatccttc gaattttact gtttttacag aattaaggca gaatttgaaa
    20281 tcgtaaaacc attttgaata agagttgctt caacccattg actccgacgg attaagttgc
    20341 tttcgtgaat gccaaaatca gccgcaattt gttcataagt gctctattct cgcatgtatt
    20401 gaatagttac cataaggaga tcgtctaggc ttaatttgct ttttcgtcca ccttttgcgc
    20461 gtttacgttg ataagctgtt tttaacacag ctaacatctc ttcaaaagtc gtgcgctgaa
    20521 cacctacaag gatcttgaaa cggctatcgc ttaattgttt acttgcttca tcatccatag
    20581 ttttattgta ttgtattttt gtttcgcagg aagtctatta ttcctttcgt tccaaggttt
    20641 ttacgctttt agcaacaagc ttacacactg agcgtttcgg acttaccata tcatttcgtt
    20701 ggagatttta tcatcaattt ttagattaaa aaaaatttcc caatcttcac aaacttctgt
    20761 agcaggaatt gtatgaatct ttctaagtat ctttcctgct tctacaccat atgtgtattg
    20821 ttggttttct gaataagcta aaatgctatc tattgcatct cttccgtcta tccattcgtg
    20881 taaagaatgt acttcgtcat cgcagagttc aatgctaatt ggtttacaca tcggaactcc
    20941 aagagaagct actttctcca tcatatcaaa ttcaaatttt tttataatct aacttcgact
    21001 tatcagaaac acgcaagaaa tatttttact gattttgatc tgtcacacaa tattttttat
    21061 catctgacca gcctttattt atggctatct tactactaaa atccatcaag cacactccga
    21121 ttcactttac aacacttttt gcagttttca ctagtaacct atccagttcg tctacacttt
    21181 tatttcctag atccattttt acattatgaa agttagtcaa ttttctctat gatgtttcca
    21241 agtttatcca atacaagaca agaatgatca tttagtggaa ttatgggaac attaacgagt
    21301 tcttcagctc tatccttatt tgctttatca ttccaggaat cataatggac actaattaaa
    21361 aactgactaa agagtcctaa tccatttttt atctttatct gatgatctga attatcatta
    21421 ggtgagacat agactttttc tcctaatagt agggctcctg cagaaaatcc tataattttt
    21481 gcctctttat taagcatatg atcgatataa cttttgaact cctgattaac ataagtagca
    21541 atatattttt ccgtatttcc accaccgatg ataattatgt cagcatctag atagctatca
    21601 agatcaatct gctcagtgtc caggagcaag taatcaatgt ttagatta
//
LOCUS       DAVDFK010000033        21529 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.33, whole genome shotgun sequence.
ACCESSION   DAVDFK010000033 DAVDFK010000000
VERSION     DAVDFK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.33"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..1409)
                     /gene="pcpA"
                     /locus_tag="VUR04_001543"
     CDS             complement(<1..1409)
                     /gene="pcpA"
                     /locus_tag="VUR04_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET5341418.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKG"
     gene            1744..1920
                     /locus_tag="VUR04_001544"
                     /pseudo
     CDS             1744..1920
                     /locus_tag="VUR04_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            2293..2439
                     /locus_tag="VUR04_001545"
     CDS             2293..2439
                     /locus_tag="VUR04_001545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET5341419.1"
                     /translation="MKAQAIVTSQGRIVSLDIAVNYCHDMKLFKMSRRNIGQAGKILA
                     DSGY"
     gene            2446..2682
                     /locus_tag="VUR04_001546"
     CDS             2446..2682
                     /locus_tag="VUR04_001546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341420.1"
                     /translation="MKIYPQAQTPRKSSKLKPLTAEDKAYNHALSKERSKVENIFAKV
                     KTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(2845..3096)
                     /locus_tag="VUR04_001547"
     CDS             complement(2845..3096)
                     /locus_tag="VUR04_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341421.1"
                     /translation="MPKTKTLAELADVILWSFDFVNDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(3386..5266)
                     /locus_tag="VUR04_001548"
     CDS             complement(3386..5266)
                     /locus_tag="VUR04_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET5341422.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(5260..6129)
                     /locus_tag="VUR04_001549"
     CDS             complement(5260..6129)
                     /locus_tag="VUR04_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5341423.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLTWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(6213..8858)
                     /locus_tag="VUR04_001550"
     CDS             complement(6213..8858)
                     /locus_tag="VUR04_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET5341424.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVATFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSMDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(8949..10229)
                     /locus_tag="VUR04_001551"
     CDS             complement(8949..10229)
                     /locus_tag="VUR04_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET5341425.1"
                     /translation="MVYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            10401..12485
                     /locus_tag="VUR04_001552"
     CDS             10401..12485
                     /locus_tag="VUR04_001552"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET5341426.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(12525..14204)
                     /locus_tag="VUR04_001553"
     CDS             complement(12525..14204)
                     /locus_tag="VUR04_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET5341427.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGE
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPTLSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGGTLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            14959..16188
                     /gene="arcA"
                     /locus_tag="VUR04_001554"
     CDS             14959..16188
                     /gene="arcA"
                     /locus_tag="VUR04_001554"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET5341428.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            16246..17262
                     /gene="argF"
                     /locus_tag="VUR04_001555"
     CDS             16246..17262
                     /gene="argF"
                     /locus_tag="VUR04_001555"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET5341429.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            17427..18374
                     /gene="arcC"
                     /locus_tag="VUR04_001556"
     CDS             17427..18374
                     /gene="arcC"
                     /locus_tag="VUR04_001556"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET5341430.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            18583..20094
                     /locus_tag="VUR04_001557"
     CDS             18583..20094
                     /locus_tag="VUR04_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET5341431.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            20116..21447
                     /locus_tag="VUR04_001558"
     CDS             20116..21447
                     /locus_tag="VUR04_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET5341432.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         6200 a         4745 c         4298 g         6286 t
ORIGIN      
        1 cctttgtctt taacccaacc aactactccc tgattagaat tctttttagg tttagctaca
       61 tcagtttctt gttttatatt atctactttt tcaacaatga tatcattact agtagataaa
      121 tttgatttaa gaacatcttt tatatgttct gatgttacat agaacttaac agtttcagga
      181 attgcaaatg tatctttttt cacagaaaac tctgtacttt tattcttaat atgaatttcc
      241 tttaatgaat ctaagacgcc acttaggaag aaggacggca atgagttgat attattacca
      301 attgttaaac tttttaattt tggtaaaccg ttcataacgt gtttaccaaa atttttaaca
      361 ttatctggta atataagttc ttttaattct aaattaccgt aaaaggctaa acgttcaata
      421 gtttctaaac tatttggtaa gctaatttct tcaagtttaa tcgcatccgc aaatgcaaaa
      481 gtaccgattt tttctaaacc ttcattcaat tcgagttttt tcaagtaaga atttttatta
      541 aacgaatatg atgcaagttc ttttgtctcc ttaggcgttt tataactttc gtcatttttt
      601 tgacttggat aataaattaa ttgagtttta tcttttgaaa acaaaacacc atcaactgag
      661 gcaaacgatt catttccttc ttcaacatca acatgtttta agctagtagt gagtctaaat
      721 agattacttc ctaatgtttt aaccgatttt ggtaatgtta gtttctctaa atttgataaa
      781 ttagcaaaag cctcatgtga tattaattct aattttgaac ttgaggaaaa ggttagcttt
      841 ttcaattttt gactaaaaga aaatgcactt gttccaatat attctagaga tgcaggcaat
      901 tcaatctctt ctaattcaga aaaatcaaaa gctctatctt caattttctc cagctgactg
      961 cctttgtcaa aaataatagt tttagcttta cttccatgga agcctttttt ttgtattttt
     1021 tttatgcttg atgggatagt aatagagcta ggatagtaga caattctacc tgtttcatct
     1081 ggataataac taaaagcttg actagctact tcagtaacgg taaatacttt atcacctact
     1141 gtgatttttg taggaatcgt gaatggtttt ccatcttgac cagcttcaaa ctctacagga
     1201 gtaactccat tacccacttg aacagttcct atgttacctt ctacagttag aaccttatat
     1261 ttgatattat tttgttgaat aatacttcca actttagtct ctttgattac ttccgaacta
     1321 ggagtatctg ctaggattgg ttcattaggg acatatgctg ctaaaataac cgcagctgta
     1381 gttaatgata atattgtagt ttttttcatt taaatttcct tacatattta ttttctaata
     1441 gatataaaat tataactttg ctagccgttg ttataaaaag ttttattcaa tcattatcta
     1501 gtagaataga gtagtacatt ttataaattg tcatctctcc ataaacacag tatatcattt
     1561 ttaaatttta agtcaaggaa aattaaccca ctttaatttc ttttttaacc cgtgttaaaa
     1621 aagaaattaa agtgggttaa aaaataaatt aactgagtaa aaactctcga aattcaattc
     1681 gctatattat cactcaactt gaacaaatac cagaaccaca aaaaacagat gtaaaggaaa
     1741 aatatggact taaaatttga aggggttgat ttagaataca aaaaagctaa aaacaatctt
     1801 ccagagtctt tctgggaaac ctactcagca tttgcaaata caaatggcgg gaaaataatt
     1861 ctcgggatag atgaaaaaaa cattgacacc taccaaagag tcaatagact ccctgcgaaa
     1921 caaaattatg aagcaagtaa acaactaacc gatgcacgat ttaagcgtct tgttggtgtt
     1981 caacgcacga cttttgaaga gatgttagct gtattaaaaa cagcttatca acttaaacac
     2041 gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc ttcttatggc cactcttcaa
     2101 tatgtgcgag aataccgcac ttatgaacaa attgcggctg attttggtat tcacgaaagc
     2161 aacttaatcc gtcggagcta atgggttgaa gtaactcttg ttcaaaggtg gtgttacgat
     2221 ttcaagaact cctctcagtt ctgaggacac ggtaatgatt gatgtgacgg aagtaaaaag
     2281 aaatgccacg ctatgaaggc tcaggcgatt gtcacaagtc aagggagaat tgtttctttg
     2341 gatatcgctg tgaactattg tcatgatatg aagttgttca aaatgagtcg cagaaatatc
     2401 ggacaagctg gtaaaatctt ggctgacagt ggttattaag gactcatgaa gatatatcct
     2461 caagcacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga agataaagcc
     2521 tataaccatg cgctatctaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa
     2581 acgtttaaaa tgttttcaac aatctatcga aatcatcgta aacgcttcgg attacgaatg
     2641 aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag gaagtctatt
     2701 gaaatactaa gcctacacag actgatttca attttaccat tcttcatagt caaaaccatc
     2761 ataatctgga tattgttctg gcaacgttcc aaccgaacgt acgagataag cttcttcgtc
     2821 ctctgtctcg atttctctca gcacttagca ttcaaaacgc cattcatcac cgaagtcgaa
     2881 aataaactta aatttttgtt tgacacttag gctatccaga tagacatttt ctatgtaacg
     2941 ttcttcaaca tcgtcactaa caaagctaag aaagtaagaa tctgcatgac tccactcaac
     3001 attatccatg aaaaatgcat gagcatgatc atttacaaaa tcgaaactcc ataaaatcac
     3061 atctgctagt tccgctaacg tttttgtttt tggaatctat atatgtcggt agcaaccttt
     3121 tttaatttga cggaaatgat ccaagcttct acagatgctg gcttttcagc ttctatttct
     3181 tgttttacta attttaactg tagcatttga aaccagatac ttcttctgtt tcacgcgaaa
     3241 caccctgcgc caagcaaggt gttcttgttt ttatactcaa tgaaaatcaa agagcaaact
     3301 aggaagctag ctgcaggttg ctcaaaacac tgttttgagg ttgcagatgg aagctgacgt
     3361 ggtttgaaga gattttcgaa gagtattaag tcgtataaat cgtcgacgct gtcgcaatgg
     3421 tatgccactg gttggctgta gttgctgcga aatccttgtc tgcgtagaag tcagtaaatg
     3481 gtaggatttc aacttccagc tcgtcgatgc ggtcaagctg accagccaga taaacctcga
     3541 tacggctttc tgctcgtttg atgcgttgca agagtccgcc catacggatg tcaactgtat
     3601 ccaaaccaaa gaccttgttt tctttcagcc attggtggct aaagagggca tggaagtctt
     3661 caatttggct tctaagttct ggtaattctt gtctggcgat ttgttgtaaa ctttctttat
     3721 catccgcttg gtaggcctga cgaatgcgtc gtcccacatc tactttgcta cttaaaatag
     3781 cattcaactg ggcctgagtt tcaaagagat aagcatagtt tccagctttt tctttaatgt
     3841 tagcaagcgt ctcagcagcc tgagcgaagt gcggtttgtc ctgttcaggt gtcatgtgtt
     3901 gatcaagaat cggacaaaga atatcctgat aaaaaacata gcggttggga ttgataccgc
     3961 tgagattgcc tggtaggtct ggtaagaggt tggcaaggtc aatctgcata aaatcctcaa
     4021 ccgttagacc agtattggtc ttgaagtgcg cagacaaacc atctaggtca ttgcgatagc
     4081 tgagttctgc ccagatttgc aagcttggta ggatagagaa ctgggcagtt tcaccaccat
     4141 tgtctcccca acccgttacg atgacttctt taatctgatt ggcacggcag gctttattag
     4201 cctcgatagc cactagacgg ctaaaatggt tgtgaggtgt aaagccaatc cacttccaag
     4261 ctccccctgc aaatgcaagg tcatggctaa tcttgtgatg attgcggaaa ttacggttgt
     4321 atttttcctc gctatcctga taataatccc agtaaaccag agtcacacgg tctttgagac
     4381 ggtctaggta gacacgagtt tcctctggaa tttccacatc acgatcgtac tggccatccg
     4441 ctgacatgag tttgaagaac atatcactcc acatctggca gtggaaacca tatttgtcag
     4501 caatatccag cacgcgctcc aagtgttggc acatgaggag actacgatcc acaacaccgt
     4561 tcaaaatcag gtagcgtccc aaaccaacca agtgggcttc gtccatcccg atattgacct
     4621 tgcgagtctt cagtttagac aacgtggcaa acatgccatc aatcaggtca taaacctttt
     4681 cttcgccaat gagaagaatg tcctctacat cacggagctc ctgcacttcc ttgacacccc
     4741 atttgacaaa ggccgacaag tgggccaagg tctggatgca tggtacaaag gtcatgtcaa
     4801 actgttgagc ataggcttct atttcctgca actcctctgc tgaataagct ccacggaaat
     4861 agccaaagta aggctgtcct tcaatctggt aagtgtcttc catgtaaagc tcaaaggttg
     4921 agtagcccat gagagccaag acctcaatca tctgcttggc agaagccaca ttcagcaccg
     4981 catttcgaga acagtcaacc atgtaagcca aatcttcgta agctgcttgt tcctcaatct
     5041 ctactttatc agcttctgct agaactgtta ccaacaagga caaggcacga taaagttggt
     5101 gaggtttgcg gtaggtcaat tgatagtgac cttcctcacc ctggatagag atagaggctt
     5161 ggtcagactg agtgacagcc acttccacat ctggtagaga aatgtgacct tttaaaacct
     5221 caatagcttg cgtttgtttg ggactaagtc ctgtaaatct taccattgct tttcctcctg
     5281 tagccagttg acaagggcac cgtagagatt ggcatctgcg tgataggtgc aggcctggat
     5341 aactggtgcg accgtgtatt cttcgtaggc atcgacaaag tcttcaacag ccttcttaac
     5401 accttggata aaatctggat tttgactgat agagccaccc agactgatga catctggatc
     5461 gatgagatac tggatattga gcaagccttg cgtcagattg cggttcatgc gctcaatggc
     5521 ttcttgacaa agagcattac cagctgcggc ctcttggtaa atcttgcgac cgtcccaatc
     5581 agtatgacca gatttttcaa tcacgtatcg taccatattc ccagttgatg ctagttgcga
     5641 ccagttatta agtttttcag caggggcaag ggttgtcatg tagccaaatt ctccacccag
     5701 accgtggcga cctcgatgaa gtctaccatt gataatcatg gctccgccaa tccctgtccc
     5761 aatcacgaca caggctgcat tttcaagctc tggatgagct agtagttcac tgagtccaac
     5821 gcagttggca tcattttcta aatggacagg tagctgataa gagctaagcg cctcatacca
     5881 agaaaagcca tggatatagg gcaccgcact gaagccatca atcacacctg tctcttgatt
     5941 gactgcacct ggaacgctca tagcaatccc actgtaatcc tgttctgaca agcgttgatc
     6001 tagccacgtt agtaaatcct ccaagttttc aggcgttgaa atacttgtct tatccagtat
     6061 tttcccatca ggagtcagac tggcaaactt aatcccagtc cctccgatat caatcgttgc
     6121 aatggtcatt gtttttacca taaaaagggg cgaatcagta gttagttctt accttttcgc
     6181 ccctcctttc ttttgatgtt tactttttga aattaaattt cttctttttt gatgaattct
     6241 gtacgaatct cttgtggagc caatagtcct gaatgaactg gatatggtcg ctcaagtaag
     6301 tcaagaatgg tttgttgatg ttctgatatg cgcacatttt cttgactcat attatagtaa
     6361 cggaggacat agccttcttc attttccgcc actttaaagg ctgttggaca aacttgcggt
     6421 atgctgagaa cagaatggct caagaggcta ccagtcgcaa ccacgcttcc ttcctgtcta
     6481 gcaagctgaa ggctggtaaa cggtgtctgc aaggctttgg cacgacgata ggctgagaag
     6541 cgttcttggg cttggtggca ttcaatcgca aattcgactt caaactcccg caagcattgt
     6601 gcttctggcg ttgggaagta gccccagtca cctagctcac ctgatgcacg caaaatggtc
     6661 acggcaatgg tgttatcccc aaggatttcg tattcattca atcccttatt ggatacagtc
     6721 accccttttt catcgtcata cagactgaca aaagcttgtt ggtgttgagg attttcagga
     6781 ttttcccatg aagcagctgg tttgtttggt cgtgtcacca cctcatagat actttcagaa
     6841 tcattacttg gacgcgtgtt atgagtcttg accaagagac ggatacggtg atccttggca
     6901 gtgttagtaa agcgagtctt gaagcggatt tgtggattgt caacgaagac agtcaactca
     6961 gtttccagag gaatgtttgt caattcttct gaccgtccag cctcacgctt cataaactcg
     7021 atgatacctt gttgctcttc ttctagcttt tcatccgcgc tgacaggcac ggtcaattca
     7081 tgtttgagca agattttagc atagcaagct gtgttttcca agacctcgtg gcccttaagc
     7141 tctgcaaaga ttggctctgt tccttttggt tggaaataga tatactcgtt tccgatgtcc
     7201 ccacggtctt caaagcggat aaagtcttca taggcttcgt gagttgtctt atcatagact
     7261 gtgatgttgt catccatact caccgttacg aatggtgtat caatcactcc gttttggtaa
     7321 ataccctcac ggtgttcttg ttctccttcc agcaattgga aggttgtcca agaaagcggt
     7381 gctaggtgaa ctggaatggt cacgcgcact tgtcgagcaa tacgagcttg gcggaacttg
     7441 tcttttggta aatcgtattc aaaattagct ccgaggtctt cgattgtagc ctctacagga
     7501 cgaccatcca agtcctccac acggtaactt ggcaagataa gagcagccat ctttttgtag
     7561 ccttctgttg ggtgcaattc cttgaaatca caagtcgcca catcaatcac tgtgctgaca
     7621 gtatcgacct tatcatgcaa gcctgtgtta atgacagtaa agagatagtc actttgagcc
     7681 ttatccgtag caattttacc cttccactcg ttgagcaaat tacttttaac aaagtttcct
     7741 acttggttga ccttggcaaa acgcgtttcc atctcgcggt gaacttcgtc cacgctacag
     7801 ccacagatac tatcatgtgg cgcattctgc aaaagtgttt tccaagcata ggtcaactgg
     7861 tccttgtggt tgtgtccacc agtgataata gtcaagggtt ctaccacttg ctctaggagg
     7921 ttgctatttt cttggaaggc ttgttttagg taaatgcggg atgaagaagt gttggcaagt
     7981 gtgtaccagc catctgtttc ctgactggtc aactcacctg taacagttga taagtgttca
     8041 ggaagcgcac cttctacagc ttgaacatat tcatcaaagg aactatgaac aaagattaca
     8101 tccgggaaga gttcatttgc cacacgaatg gcttcgctca gatttttctg tacaggctgg
     8161 tggtcacagc cgttcatcat caaccattgg ttggtcgaag cgtaggcacg cacatctgac
     8221 aatttttgtt tccagaaggt caaggcctca tctttgtcaa ctggaatttc attcccgtta
     8281 ctgtaccagt tggcaaagag aatacctaaa acacgactac catccacacc ctgccagtac
     8341 atttctgaaa actgggatgt aaactgctca tcttcaagga cttggttgtc aaatccaatc
     8401 ggcttcacac cacgaccaaa ggtcgccacg tgaatgcctg atttttgaag aatttgaggc
     8461 gcttgtccca tatttccaaa ggtatctgga aagtagccaa tctgggttga tttaccccat
     8521 ttggcagctt cttgttgacc aatcaaggta ttgcggacat tggcttcact ggagatcaaa
     8581 taatcatcct gcaagatgta aaagggacca attttaagct tgccctcgtc aatgtagcgt
     8641 tggaccttgt cacgattttc agggcgaatt tgtaagtagt cgtcaaggac aatagtttgt
     8701 ccatccaagt ggaaactctt gaactcaggg tcattttcaa agagatcaaa gagattgtca
     8761 aacaattcca ccaactgcat acgatgactt tcaaaaggca agtaccactc acggtcccag
     8821 tgactatgtg agataatatg tacaacaaca ttttccatga agtaaaacct cattctaaat
     8881 ttaaatttta acgttttaaa tgtaaacttg tgattctgat aagaatcggt tgagctaaag
     8941 cgagcccctt agcgaatatc caagtaatcc aagaccaact cacagaacat catgttagcc
     9001 caggagaacc attcacgaga gtagagggtc ggatcatcta catgaaagct ttcgtgcatg
     9061 acacctgtac caccatcgca ggcaaccagc tgatccagca agaatttttt ctctgcctta
     9121 tctcttgttg tcaagccttg gatagaaagg gcgattggcc agatatagcg atagaaggta
     9181 tgagaactgc cgagaccgct tgcgtattct ccttggtaga agtatggatt ttcagagctc
     9241 aaaatggtac gacgagtagc ttgatacact tcatcatcga ccgaacagta gcccagatag
     9301 ggcgcagcta gtagacttgg tacatttgga tcatccatga tgctggcatt tcctaggcca
     9361 tccacttcaa aagcgtaaat cttttcgccc ttgctgttgg tggtgtaagc gtagtttttg
     9421 attccttctt ggatttcatc ctgaagacgc ttggcatcag caataacact ctggctatca
     9481 gctaggttta atgctgcgaa gatttcttgc acataaccca agactactac agcaaacata
     9541 tttgacggaa tcaagtaact atactggcaa cagtcatcac tcggacgaaa agctgaccaa
     9601 gtcatacctg tcactgcaaa gtcaggtcca aagccatcat ttaccaaggt gtcttcctta
     9661 cggtccgtat ctcggacaaa acgataagga gagttcttgt ggtcttgttc caccgtccac
     9721 agatggagaa tttccttagt cgctgcgaca aaaatctcat caaactgact agtctcgcca
     9781 gtctctttcc agaggagata agccaactgc aaaggatagc aaagcgaatc cacctcatac
     9841 ttgcgctccc agatccagcc gttaaggtct gtgtggtcag tctcgtggtg ccctttccag
     9901 ttctcctcaa tgttgaagga gttagcatag ggatccttga gtaccaaggt catctgacgt
     9961 ttgaccaaac ctgcaatggt ctgacgcagg agggcatctc ttttagctac atgaaggtag
    10021 ggtctgagtt gggctgtcga atctcgaagc cacatggcag gaatatcccc agtcaagaca
    10081 aaagttgaac catcttctaa gatttcaacc gtattgtcca aggtatcggt gtagcaacgc
    10141 tcgaaaacat ccacccactc tggatggtcc ttagcccgct ctgctacttc atctagccat
    10201 tctctaacaa tttctttcga ataaaccatt ttaaatttta cctctttcaa acaagtttca
    10261 tgttcagtat atagcttttg agacagaaaa tacatacaca aatgatagtc atttttctac
    10321 aaaatagtta tctttgaaac tccttttcta aaggccctct ttttctgata taatgtagaa
    10381 aaacagctaa aggaaagact atgaaaccac tacttgaaac catcgatacc cgctttggaa
    10441 ctaccaacaa gcatgccttt tctcggggaa ataccctgcc atacacaggc gtgccttttg
    10501 ggatgaatta ctttgtgccc cagaccagtg accaggatgg agcttggttt tttgatccgc
    10561 atctgcctat ctttcagggg attcgattaa ctcaccagcc cagtccttgg attggggact
    10621 actcttggct ccttctgaca cccgtcacca gtcaactggg tggagacagc ctctttcacc
    10681 gccaatcttc ctatgatagg gataaggcct ctttccaacc tcattatcta aagattttct
    10741 ccctgcgcta tcagattgaa acccagctca caccgacttg ctacggtgct tctattcgtt
    10801 tgaagcaaaa gcaaggcaaa gccctctccc tctatcttca cgcagcagat gaactaacag
    10861 tagagcaagt agataagcga actcttgccc tgcgacaaga aggtaaaact gaaaccaaca
    10921 aaaattcgct aacgatgttc actgccctgc aaatgaacac ggatattctt gctatcagcc
    10981 aagaagctgg ggactggcga attgacttag caagtagtca aaccgagatg caactagcca
    11041 cttctttcat ctctccttct caagctctaa tcaatctacc tcaagaagat tttgatagct
    11101 gtaaaacaag tgcccaagcg gattgggaaa atctcctcca tcgttttgac attatagaga
    11161 caggagaggc tgaccgaacc ttctttgacc actgtctcta cagactcttc ctcttcccac
    11221 agacttttta tgaggttgat gagtcagggc aagccatcca catggatctg gctactggta
    11281 ctgtcaagcc tggtgtcctc tttagcaaca atggtttctg ggataccttc cgcaccacct
    11341 tccccctctt tgcccttatc ataccggagc actatcaacg ctttttagaa ggtttcctca
    11401 atagctaccg cgatactggt ttccttccaa aatggctggc tccagatgaa cggggtatga
    11461 tgccaggtac acttttagac ggtattatcg cagatagcgc ctgcaaggac atggcccctg
    11521 acctagaagg agaactcttc caagccatgc tcgaaacagc cagcaaagcc gaccctctcg
    11581 gcatcaatgg ccgccacgga ctagcccaat accaagaact aggttacctc tctaccgacc
    11641 accacgaaag tgttagccat actctagact atgcctatag tgacttttgt atcgccagct
    11701 gtgccaaaaa actagagaac atagaaatcg ctgaaaccta caaggctgct tcacaaaatt
    11761 accgccagct atttgacgct gagacaggtt acatgcgagc acgagacaat caaggaaact
    11821 ttcaccctga cttctctcct tatagttggg ggcgagacta cgctgaatgc tctgccattc
    11881 aagctacttt aggcgttctc cacgacatcc ctggcttaat ccaactgatg ggtggaaaag
    11941 aaacctttag caactatctt ttgaaaacct gtcaagatgc tcccctcttt gaaacaacag
    12001 gctatggtta cgaaattcac gaaatgagcg agatggctac tgctcctttt ggacaaatag
    12061 ccatttccaa ccagcctagt ttccacattc cttatctatt ccgctacagc gattaccctg
    12121 actacactgc ccttcttatc aagacgctcc gtcagaaagc ttttcaccca agttgggaag
    12181 cctatcctgg agatgaagac aatggtagtc tctctgcttg gtacatctgg tcagctctcg
    12241 gattttatcc aacctgtcca ggaaaaccaa gctatgacct cggaatccct ctctttgacc
    12301 atctacgagt ctacctagct aaagaagata aatggctgga tatccatact aaacaaaacc
    12361 acaaccattt taactttgtc aaagaatgcc gactggacaa aacactcgta tcaactattc
    12421 aacaccaaga cctcttaaaa gctgaacaac taactttcac cctcagctgg ttaccaagtc
    12481 actaataacc aaaagaacct ttgcatcgcg caaaggttct tcttttatga aacttggact
    12541 tgaagttgat ccacaagctg accatccacc gttaggttca gatagaaatc caaggtttta
    12601 tctcctgcga aatacaaggt tggtagcgtc agactttttt cagtctcacc agcttgaaac
    12661 gcaaggactt gaatctcatc ctgataggcg acaccatgga cacctgtccc cggttgaatc
    12721 gaaatcttag cctctaaaga ggagctactt tcactacgtt caatcctaaa atgaagagtc
    12781 cctccctttg ccacagctag gcttttttct gcaaatgcta gttcctgaac aacttctttt
    12841 tttgataacc caggagtttt ataaagggaa atcttggtca gtagaggcat agattgtgct
    12901 tcggtaatca tcacgcgcac cttctgtgcc tctactagcg gacctcgcaa gaggcgctta
    12961 tgaccaactg tgaagcccct gccaaattcc tgccagacac catccacctc tacttgcaca
    13021 tggaaagcag cgattcgttg ccctagcttc aaatcttctc ttaactcaat tacatcaaaa
    13081 gttttaggag aacctaagtc gagttctaac tggatgggca agtctgcatc gcttgcccaa
    13141 gagctggtct caaggccgtc tgtcaaatgg cgacaagcaa agtctgcgga aagagttgga
    13201 ccagatacct cagctcccag agccaaatct tctttataga gctcattgcg ataggtcgca
    13261 aattcataaa gtcgttcaat atcctttgca tcaaagagcc cagcttgatt cggcggaata
    13321 ttaagcaaga gtggagttcc tcgccctact gagtgaaagt agatttcgac caactcctcg
    13381 agagacttag gatcctgatc ctcatggtag aaccagcctg gacggatgga aacatctgcc
    13441 tctccgattg aaaaaatcgt gcccgaggga tccccgtgct gaagatagtc cagctctgct
    13501 tctgttccta gtttatcagg attcaccttt tgccacagtg gatcacctgc ataccctcgt
    13561 tcattgccaa tccagcggat actggtgcct tctgttgaaa aaatcaaaca atcgccctgc
    13621 aagtcacgaa tggtttcaaa ccatttttca aattcataat taaccttttg cgcgccctct
    13681 cctctggcac catccatcca aacctcagcg aacttaccag cattcccata gttaggattt
    13741 gataagattt ccttcaactg agccagataa taggcattgt agtccgcttc tcggtccaca
    13801 tgatagaggg gactatgggc atcccacggt gacaggtaga cccccatatc catatcaaac
    13861 tctgtggcag cttgggatac ttcaaggagc aagtcgccct ctcctctcct ccaaggactg
    13921 accttaaccg aataatctgt gtgagctgtc ggataaagga caaagccatc gtggtgcttg
    13981 accaccaaaa tcaacttttt gaagcccgtt tccttgagca cacgaaccca ctcacgcgca
    14041 tccaactgac tcgggttaaa gcgctcagga tcctcctgtc cagtccccca ttcttggtca
    14101 taaaaagtat taggaccgaa gtggataaaa gctgctagtt catctcccag ataagctagc
    14161 tgagtctgac ttggtaacgg tccatgcggt ttgattttct tcatcgttat atatctcctt
    14221 ctttagcaac ttctcttgtt cacaaggtta tccacaggtt gtggataata aaccatgatc
    14281 taacagccag ctctttccaa ctccaactgg taggctcagg attttgctcc tcaatattcc
    14341 ctcttcaaac agctctgtca tatggttctg ctaacacctc tcagaatgct actctccata
    14401 attattctca ggcttctttc aggtcattgt gtgaagacca ttcactctcc agacttttcc
    14461 acagattgtg aataagtgat tattctaaac tatcacctcg tcgactataa caaaaaataa
    14521 aaagagggtc aataagataa ttatctcttc ctaaatactc agaaaagatt ctataatttg
    14581 tacaattgaa caagaaatgc ttctccaaaa tctatcttca aaagaatgtt gcatcttttt
    14641 atcctttcac acaaacattt ctctttatac agatccaagt gataaccaga tgataattgg
    14701 acactttttg gtcatttgta tattttttga aaaatttttt aaaaaaattt tatatccttt
    14761 ttatagaagt ttatgcattt gtatctatgt attctatcct atgttatgta taataacata
    14821 aaattgtgct aaacatcata atttatatta ttttccgaga aattatagcc attgacatta
    14881 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    14941 ttttaaggag gaaaatacat gtcttctcat ccaattcagg tcttctcaga aattgggaaa
    15001 ctgaaaaaag ttatgttgca ccgtccaggc aaggagttag aaaacttgtt gccggactat
    15061 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    15121 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    15181 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    15241 gccaacatcc gtgatcgtca aaccaaggtt gctattcgtg aattgcttca cggcatcaag
    15301 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    15361 attcctgacg aagctaaaga tctaactgac ttagttgaat cagattatcc atttgcaatt
    15421 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    15481 tcgcttaacc acatgtttgc agatactcgt aaccgtgaaa cactctacgg taagtatatc
    15541 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    15601 acgcgtatcg aaggtggaga cgagctaatt ctttctaaag acgtccttgc agtaggtatc
    15661 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    15721 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    15781 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    15841 gaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaattgt tgaagagaaa
    15901 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    15961 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    16021 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    16081 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    16141 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggc
    16201 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    16261 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    16321 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    16381 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    16441 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    16501 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    16561 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    16621 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    16681 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    16741 cgtaacaacg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    16801 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    16861 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    16921 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    16981 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    17041 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    17101 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    17161 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    17221 atggctgcga cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    17281 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatataatg
    17341 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    17401 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    17461 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    17521 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tttgattatc actcacggta
    17581 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    17641 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    17701 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    17761 taacgcaagt tatcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    17821 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    17881 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    17941 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    18001 gtggcggtat tcccgtcgtc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    18061 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    18121 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    18181 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    18241 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    18301 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    18361 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    18421 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatactag ttttagactt
    18481 taatatggta aaacaaatat aaatagaaag cgttttcttg aatgtttatt taagaaagta
    18541 gttggttttt tacactttgt tagacatcag gaggaaaaac aaatgagtga aaaagctaaa
    18601 aaagggttta agatgccttc atcttacacc gtattattga taatcattgc tattatggca
    18661 gtgctaactt ggtttatccc tgcgggggcc tttatagaag gtatttacga gactcagcct
    18721 caaaatccac aagggatttg ggatgtcctc atggcaccga ttcgggctat gctaggtact
    18781 catccagagg aaggttcgct cattaaagaa acgagcgcag cgattgatgt agccttcttc
    18841 atccttatgg ttgggggttt ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg
    18901 attgcctcta tcgtgaagaa gtataagggc cgcgaaaaaa tgttaatttt ggtactgatg
    18961 cctttgtttg ccctcggtgg tacaacttat ggtatggggg aagaaacaat ggccttctat
    19021 ccactccttg tgccagttat gatggccgtt ggttttgata gcctgactgg tgttgcaatt
    19081 attttgctcg gttctcaaat cggctgtttg gcatctactc tgaatccatt tgcgacaggt
    19141 attgcttcag cgactgcggg agttggtaca ggggacggta tcgtacttcg tctgatcttc
    19201 tgggttacct tgactgctct tagtacttgg tttgtttacc gttatgcgga taagattcaa
    19261 aaagatccga ctaagtcact ggtttatagt actcgcaaag aagatttgaa acactttaac
    19321 gtagaagaat cttcatctgt agaatctaca cttagcagca aacaaaaatc agttctcttc
    19381 ttatttgtgt tgacattcat cttgatggta ttgagcttca ttccatggac agaccttggc
    19441 gttaccattt ttgatgactt taatgcttgg ttgactggtc ttccagttat tggtaatatt
    19501 gtcggttcat ctacttctgc actaggtact tggtacttcc cagaaggcgc aatgctcttt
    19561 gcctttatgg gtatcctgat tggtgttatt tatggtctta aagaagataa gattatctct
    19621 tccttcatga atggtgctgc tgacttgctc agtgttgcct tgatcgtagc gattgctcgt
    19681 ggtattcaag ttatcatgaa cgacggtatg attaccgata caatcctcaa ctggggtaaa
    19741 gaaggcttga gcggtctatc ttcacaagtc tttatcgttg taacttatat cttctatcta
    19801 cctatgtcat tcttgatccc atcttcatct ggtcttgcca gcgcaactat gggtatcatg
    19861 gctccacttg gagaatttgt aaatgtccgt cctagcttga ttatcactgc ttaccaatct
    19921 gcttcaggtg tcttgaactt gattgcacca acatctggta ttgtgatggg agctcttgca
    19981 cttggacgta tcaacattgg tacttggtgg aaattcatgg gcaaactcgt agtcgctatt
    20041 attgtagtga ccatcgccct tcttctcctt ggaaccttcc ttccattcct ataaaatagt
    20101 gagtgaggtg attccatgaa aatagatata acaaatcaag ttaaagatga atttcttata
    20161 tcattaaaaa ccttgatttc ctatccttca gtactcaatg aaggagaaaa tggaacacct
    20221 tttggacaag caatccaaga tgtcctagaa aaaactttag agatttgtca agacataggt
    20281 ttcactacct atcttgaccc taaaggttat tacggatatg cagaaatcgg tcagggagca
    20341 gagcttctgg ccattctctg tcatttggat gttgttccat caggtgatga agcagattgg
    20401 cagacaccgc catttgaagc aactatcaaa gacggctggg tattcggacg tggtgtccaa
    20461 gatgataaag gcccttcgct cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt
    20521 attcagttca aaaagcgcgt acgctttatc tttggtaccg atgaggaaac cctctggcgc
    20581 tgcatggcac gctacaatac catcgaagaa caggccagca tgggctttgc acctgactca
    20641 tcttttcctc tgacctatgc tgaaaaaggg cttctacagg tcaaacttca tggccctgga
    20701 tcggatcaac tagagcttga agtaggaggc gcctttaacg ttgtaccaga caaggccaac
    20761 taccaaggtc ccctctatga acaggtttgt aacggtctca aagaagctgg ttatgattac
    20821 caatccactg aacaaaccgt aacggttctc ggagtgccaa agcatgctaa ggatgctagt
    20881 caaggtatca atgctgtcat ccgactagct accattcttg ctcctctcca agaacaccct
    20941 gctctcagtt ttcttgcaac acaagcaggt caagacggca caggaagaca aatctttggt
    21001 gatatagcag atgaaccttc tggtcaccta tcctttaatg tcgcaggtct catgatcaat
    21061 catgaacgtt ctgaaatccg tattgacatt cggactcctg tcttagctga taaggaagaa
    21121 ctagtagagt tgcttacaag atgtgcacaa aactaccaac tccgctacga agagtttgac
    21181 tatctagcgc ctctatacgt cgcaaaagac agtaaactcg ttagcacact gatgcaaatc
    21241 taccaagaaa agactggcga taacagtcct gctatttcat ccggtggtgc cacttttgct
    21301 cgcaccatgc caaattgtgt agccttcggc gccttattcc caggagcgaa gcagacagaa
    21361 catcaggcaa atgaatgtgc cgttctagaa gatttgtacc gtgctatgga tatttatgcc
    21421 gaagccgtct atcgacttgc aacttaatca ggcaactgtt tctacaaaaa aaaatcgacc
    21481 gattaatgaa ctgcacccca aaagttagac agaataaatc taacttttg
//
LOCUS       DAVDFK010000034        21365 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.34, whole genome shotgun sequence.
ACCESSION   DAVDFK010000034 DAVDFK010000000
VERSION     DAVDFK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.34"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(163..1083)
                     /gene="cysK"
                     /locus_tag="VUR04_001559"
     CDS             complement(163..1083)
                     /gene="cysK"
                     /locus_tag="VUR04_001559"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET5341433.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKILALAPDNGERYLSTALYEL"
     gene            complement(1368..2003)
                     /locus_tag="VUR04_001560"
     CDS             complement(1368..2003)
                     /locus_tag="VUR04_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET5341434.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2059..3357
                     /locus_tag="VUR04_001561"
     CDS             2059..3357
                     /locus_tag="VUR04_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5341435.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3354..4016
                     /locus_tag="VUR04_001562"
     CDS             3354..4016
                     /locus_tag="VUR04_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET5341436.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4096..4644
                     /gene="raiA"
                     /locus_tag="VUR04_001563"
     CDS             4096..4644
                     /gene="raiA"
                     /locus_tag="VUR04_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET5341437.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            4780..6753
                     /locus_tag="VUR04_001564"
     CDS             4780..6753
                     /locus_tag="VUR04_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET5341438.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            6750..7202
                     /gene="rplI"
                     /locus_tag="VUR04_001565"
     CDS             6750..7202
                     /gene="rplI"
                     /locus_tag="VUR04_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET5341439.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7246..8598
                     /gene="dnaB"
                     /locus_tag="VUR04_001566"
     CDS             7246..8598
                     /gene="dnaB"
                     /locus_tag="VUR04_001566"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET5341440.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8600..8866
                     /locus_tag="VUR04_001567"
     CDS             8600..8866
                     /locus_tag="VUR04_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341441.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            8955..10301
                     /gene="cbpD"
                     /locus_tag="VUR04_001568"
     CDS             8955..10301
                     /gene="cbpD"
                     /locus_tag="VUR04_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET5341442.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKPEPLASGTVIDYYYPG
                     EKVHYDQIFEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGENVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSHSSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGLWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10384..10486
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10557..10847
                     /locus_tag="VUR04_001569"
     CDS             10557..10847
                     /locus_tag="VUR04_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET5341443.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10810..11568
                     /locus_tag="VUR04_001570"
     CDS             10810..11568
                     /locus_tag="VUR04_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341444.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            11607..12614
                     /locus_tag="VUR04_001571"
     CDS             11607..12614
                     /locus_tag="VUR04_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5341445.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12614..13342
                     /locus_tag="VUR04_001572"
     CDS             12614..13342
                     /locus_tag="VUR04_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341446.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13461..13919
                     /locus_tag="VUR04_001573"
     CDS             13461..13919
                     /locus_tag="VUR04_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET5341447.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            13921..16353
                     /locus_tag="VUR04_001574"
     CDS             13921..16353
                     /locus_tag="VUR04_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5341448.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            16995..17648
                     /gene="rr06"
                     /locus_tag="VUR04_001575"
     CDS             16995..17648
                     /gene="rr06"
                     /locus_tag="VUR04_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET5341449.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17645..18976
                     /gene="hk06"
                     /locus_tag="VUR04_001576"
     CDS             17645..18976
                     /gene="hk06"
                     /locus_tag="VUR04_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET5341450.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDENGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            19059..19586
                     /locus_tag="VUR04_001577"
     CDS             19059..19586
                     /locus_tag="VUR04_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET5341451.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCFVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19665..>21365
                     /gene="pspC"
                     /locus_tag="VUR04_001578"
     CDS             19665..>21365
                     /gene="pspC"
                     /locus_tag="VUR04_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HET5341452.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGN
                     NSTVTSSGQDISKKYADEVKSHLEKILSEIQTNLDRSKHIKTVNLINKLQDIKRTYLY
                     ELNVLEDKSKAELPSKIKAKLDAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKAKAQ
                     KEEDHRNYPTITYKTLELEIAESDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     QAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRGKRGALGEQATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKAQKEEDRRNYPTNTYKTLEL
                     EIAESDVKVKEAELELVKEEAKESRNEEKIKQEKAKVESKKAEATRLEKIKTDRKKAE
                     EAKRKAAEEDKVKEKPAPKPEKPAEQPKAEKTDDQQAEEDYARRSEEKYNRLTQQQPP
                     KTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGSMATGWLQN
                     NGSWYYLNANGAMATGWLQYNGSWYYLNSNGAMATGWLQYNGSWYYLNSNGAMVTGWL
                     Q"
BASE COUNT         6750 a         3529 c         4865 g         6221 t
ORIGIN      
        1 tcttccaaac gaggaaactc tcgtaaacaa agaggtttta gaggcctatt taccgtggac
       61 taaagttgta caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt
      121 ctctagtctg gagatttttc aatagacttc gttattggac ggttacaatt cataaagtgc
      181 tgtagagaga taacgttcac cgttatctgg tgctagggca aggatttttt tacctgtacc
      241 taattttttg gcaacctcga tggctccgta gatagctgca gctgaggaaa tccctacaag
      301 gaagccttct tttccaccaa tttcacgtcc gagtgcaaga gcgtcatctg atgttacacg
      361 aacgatacca tcataggctt tagtatcaag tgtatcagga ataaatccag ctgagatacc
      421 ttgaattttg tgaggaccag gtttttcacc agatagaata gcagattcat ctgcttctac
      481 tgcaaaaact tgaatgttag aattttctga tttgagtgca tgagaaacac cagaaatcgt
      541 tccaccagta cctactccag caacaaaggc atctaatcca tctttaccga aagcagctag
      601 tatctcagct cctgttgttc tttcgtgtac ttctggatta gctggattgt caaattgaag
      661 aggaaggaaa ccatcacgtt cagcagcgat ttcttgagcc ttagcaatag cacctttcat
      721 tccctcgcta ccaggagtta ggacgagttc agcaccataa gcttggataa ttttacgtcg
      781 ttctacactc atagtttcag gcataacgat gacgacttta taccctttag cagcacctac
      841 ccatgaaagt ccaataccag tgtttccact tgttgcttca acaatagtag aaccaggttt
      901 cagaatacca tcttgttcag ctttttcaat catgctaagg gcaatacggt cttttacaga
      961 tgaaccagga ttaaatgctt caagctttat atagacgtct gcagcacctt ctggcacgat
     1021 gttgttaagt ttaacaatcg gtgtttgacc gattaattca gtaatgttgt tataaataga
     1081 catatgaata cctctttgta taagatatct ttagtataac gctatctata ccatttgtaa
     1141 aatatagaaa tcctatcgaa gcgataggat ttctatatat catagatcaa agtcattaat
     1201 tttcaagtga ttgcgttcag ctaattctag taaataggtg tgaaggaaaa cgatatcagg
     1261 tttcgtttga attgcttcat tttctagtat attttggtac gcatcttttt attttgctcg
     1321 ctaaagtagt tgtgagaatg tcaacgaaac gctgtattat tcattgttta cactaagttt
     1381 acaggaactt caacctctcg taaaccttgg tcagttaaag tgacttttcc attaaaaaac
     1441 tccacaagtg cagctttaat agtttctttt tcttccttat caacataaat catcgtatcg
     1501 acttgatctg taaagtttgt atccagctcc atgagatcat gttctttaag gaagttactg
     1561 tactcttggt actgagcata agacatttga atagcaatgc cagcctgttc ttttatttca
     1621 ataataccaa tttctttgac agctaaggcg acactgccgg cgtaagcacg aattagtcct
     1681 ccagcgccta gtttaatacc accaaagtag cgtgtcacga ccacacagac attggtgaga
     1741 ttgtgatttt ctagtacccc aagcatggga acaccagcag taccactagg ctcaccatca
     1801 tcacttgtac gtttaatttc actacgttct ccaataataa aggcagagca gttatgtgtc
     1861 gctttgtagt gttctttttt gatggcagta atgaagtcac gagcctcttc ttcgctataa
     1921 acacgcttgg catggcagat aaagcgagat tttttgattt cttcttggac ttggccgtcc
     1981 tctttaattg tcctaaattc catgatttaa ttgtactaaa aaataatcta aagtgctagt
     2041 ttttacgaat aaagaagtat gaaagtaaat ttagattatc tcggtcgttt atttactgag
     2101 aatgaattaa cagaagaaga acgtcagttg gcggagaaac ttccagcaat gagaaaggag
     2161 aaggggaaac ttttctgtca acgctgtaat agtactattc tagaagaatg gtatttgccc
     2221 atcggtgctt actattgtcg agagtgcttg ctgatgaagc gagtcagaag tgatcaaact
     2281 ttatactatt ttccgcagga ggattttccg aagcaagatg ttctcaaatg gcgcggccaa
     2341 ttaactcctt ttcaagagaa ggtgtcagag ggactgcttc aagcagtaga caagcagaag
     2401 ccaaccttag ttcatgcggt aacaggagct ggaaagacag aaatgattta tcaagtagtg
     2461 gctaaagtga tcaatgcggg tggtgcagtg tgtttggcta gtcctcgcat agatgtttgt
     2521 ttggagctgt acaagcgcct gcaacaggat ttttcttgcg gtatagcttt gctacatgga
     2581 gaatcggaac cttattttcg aacaccacta gttgttgcaa caacccatca gttattgaag
     2641 ttttatcaag cttttgattt gctgatagtg gatgaagtag atgcttttcc ttatgttgat
     2701 aatcccacgc tttaccacgc tgtcaagaat agtgtaaagg agaatggatt gagaatcttt
     2761 ttaacagcga cttcgaccaa tgagttagat aaaaaggtcc gtttaggaga actaaaaaga
     2821 ctgagtttac cgagacggtt tcatggaaat ccgttgatta ttccaaaacc aatttggtta
     2881 tcggatttta atcgctactt agacaagaat cgtttgtcac caaagttaaa gtcctatatt
     2941 gagaagcaga gaaagacagc ttatccgtta ctcatttttg cttcggaaat taagaaaggg
     3001 gagcagttag aagaaatctt acaggagcaa tttccaaatg agaaaattgg ctttgtatct
     3061 tctgtaacag aggatcgatt agagcaagta caagcttttc gagatggaga actgacaata
     3121 cttatcagta cgacaatctt ggagcgtgga gttaccttcc cttgtgtgga tgttttcgta
     3181 atagaggcca atcatcgttt gtttaccaag tctagtttga ttcagattgg tggacgagtt
     3241 ggacgaagca tggatagacc gacaggagat ttgcttttct tccatgatgg gttaaatgct
     3301 tcaatcaaga aggcgattaa ggaaattcag atgatgaata aggaggctgg tctatgaagt
     3361 gcttgttatg tgggcagact atgaagactg ttttaacttt tagtagtctc ttacttctga
     3421 ggaatgatga ctcttgtctt tgttcagact gtgattctac ttttgaaaga attggggaag
     3481 agaactgtcc aaattgtatg aaaacagagt tgtcaacaaa gtgtcaagat tgtcaacttt
     3541 ggtgtaaaga aggagttgaa gtcagtcata gagcgatttt tacttacaat caagctatga
     3601 aggatttttt cagtcggtat aagtttgatg gagacttcct gttaagaaaa gttttcgctt
     3661 catttttaag tgaggagttg aaaaagtaca aagagtatca atttgttgta attcccctaa
     3721 gtcctgatag atatgctaac agaggattta atcaggttga gggcttggta gaggcagcag
     3781 gctttgagta tctagattta ttagagaaaa gagaagagag agccagttct tctaaaaatc
     3841 gttcagagcg cttggggaca gaacttcctt tctttattaa aagtggagtc actattccta
     3901 aaaaaatcct acttatagat gatatctata ctacaggagc aactataaat cgtgttaaga
     3961 aactgttgga agaagccggt gctaaggatg taaaaacatt ttcccttgta agatgaggaa
     4021 aaaatttgca aaaatagaat gaaagcgtta taataaaatc ataaaaacaa aaatgtttag
     4081 aaagaaggta ttcatatgat taaatatagt atccgtggtg aaaacctaga agtaacagaa
     4141 gcaattcgtg attatgtagt ttctaaactc gaaaagatcg aaaagtactt ccaaccagaa
     4201 caagagttgg atgcccgaat taacttaaaa gtttatcgtg aaaaaacggc taaagtggaa
     4261 gtaacgattc cgcttggatc tattactctc cgcgcagaag atgtatctca agatatgtat
     4321 ggttcaattg accttgtaac tgataaaatt gaacgtcaga ttcgtaaaaa taaaacaaaa
     4381 atcgagcgta aaaataaaaa taaggtagca actggtcaat tatttacaga tgctttggtg
     4441 gaagattcaa atgttgtcca gtctaaagtt gttcgttcaa aacaaattga tttaaaacca
     4501 atggatttgg aagaagcaat tctacaaatg gatttattgg ggcatgattt ctttatctat
     4561 gtggatgttg aagatcagac aaccaatgtg atttatcgtc gtgaggatgg cgaaattggt
     4621 ttgttagagg ttaaagaatc ttaatttcaa tatgtgtaaa ggtaggttta ctgaattgta
     4681 aactaccttt ttcttataat tgatagaatt actgattaca cctttaaaaa gtcgcttttt
     4741 gaggggtatt atggtataat gggtgccaag aggttttgaa tgaaaaaatt ttatgtaagt
     4801 ccaatttttc ctattctagt aggattgatt gcgtttggag tcttatccac tttcattatt
     4861 tttgttaata ataatctgtt gacggtttta attttgtttc tttttgtagg aggctatgtt
     4921 tttttattta agaaactgag agtgcattat acaaggagtg atgtagaaca gatacagtat
     4981 gtaaaccacc aagcggaaga aagtttgaca tctctattgg aacaaatgcc tgtaggtgtt
     5041 atgaaattga atttatcttc tggagaggtt gagtggttta atccctatgc tgaattgatt
     5101 ttgaccaagg aagatggtga ttttgattta gaagctgttc aaacgattat caaggcttca
     5161 gtaggaaatc cgtctactta tgccaagctt ggtgagaagc gttatgctgt tcatatggat
     5221 gcttcttccg gtgttttgta ttttgtagat gtatccaggg aacaagccat aacagatgaa
     5281 ttggtaacaa gtcgaccagt gattgggatt gtctctgtgg ataattatga tgatttggag
     5341 gatgcaactt ctgagtcaga tattagtcaa atcaatagtt ttgtagctaa ttttatatca
     5401 gagttttcag aaaaatacat gatgttttct cgtcgggtaa gtatggatcg attttatcta
     5461 tttactgact acacggtgct tgagggcttg atgaatgata aattttctgt tattgatgct
     5521 ttcagagaag agtcgaaaca gagacagttg cccttgacct taagtatggg attttcttat
     5581 ggcgatggaa atcatgatga gatagggaaa gttgctttgc tcaatttgaa cttggctgaa
     5641 gtacgtggtg gcgaccaggt ggttgttaag gaaaacgacg aaacgaaaaa tccagtttat
     5701 tttggtggtg ggtctgctgc ttcaatcaag cgtacacgga ctcgtacgcg cgctatgatg
     5761 acagctattt cagataagat tcggagtgta gatcaggttt ttgtagtcgg tcacaaaaat
     5821 ttagacatgg atgctttggg ctctgctgta ggtatgcagt tgttcgccag caatgtgatt
     5881 gaaaatagct atgctcttta tgatgaagaa caaatgtctc cagatattga acgagctgtt
     5941 tcattcatag aaaaagaagg agttacgaag ttgttgtctg ttaaggatgc aatggggatg
     6001 gtgaccaatc gttctttgtt gattcttgta gaccattcaa agacagcctt aacattatca
     6061 aaagaatttt atgatttatt tacccaaacc attgttattg accaccatag aagggatcag
     6121 gattttccag ataatgcggt cattacttat atcgaaagtg gtgcaagtag tgccagtgag
     6181 ttggtaacgg aattgattca gttccagaat tctaagaaaa atcgtttgag tcgtatgcaa
     6241 gcaagtgttt tgatggctgg tatgatgttg gatactaaaa atttcacctc gcgagtaact
     6301 agtcggacat ttgatgttgc tagctatctc agaacgcgcg gaagtgatag tattgctatc
     6361 caggaaatcg ctgcgacaga ttttgaagaa tatcgtgagg tcaatgaact tattttacag
     6421 gggcgtaaat taggttcaga tgtactaata gcagaggcta aggacacgaa atgctatgat
     6481 acagttgtta ttagtaaggc agcagatgcc atgttagcca tgtcaggtat tgaagcgagt
     6541 tttgttcttg cgaagaatac acaaggattt atctctatct cagctcgaag tcgtagtaaa
     6601 ctgaatgtac aacggattat ggaagagtta ggcggtggag gccactttaa tttggcagca
     6661 gctcaaatta aagatgtaac cttgtcagaa gcaggtgaaa aactgacaga aattgtatta
     6721 aatgaaataa aggaaaagga gaaagaagaa tgaaagtaat ctttttagca gatgttaaag
     6781 gaaaaggtaa aaaaggcgaa attaaggaag taccaacagg gtatgcgcaa aactttctta
     6841 tcaaaaagaa tctagccaaa gaagcgactg ctcaagctgt aggtgaactt cgtggtaaac
     6901 aaaaatcgga agaaaaagct cacgctgaga tgattgcaga aggaaaagca attaaagcac
     6961 aacttgaagc agaagaaact gttgtagaat ttgttgaaaa agttggtcca gatggtcgta
     7021 cctttggttc tattaccaat aagaagattg cagaagaatt gcaaaagcaa tttggaatta
     7081 agattgataa acgtcatatt caagtacaag ctccgattcg agcggttggt ttgattgatg
     7141 tgccagtgaa aatctatcaa gatatcacaa gtgtaatcaa tcttcgtgtg aaagaaggat
     7201 aagtttacac cttcttgaca agattgtaaa aggaagggaa gtctgatggc agaagtagaa
     7261 gagttacgag tacaacctca agatatctta gctgagcaat ccgttttagg ggctatcttt
     7321 attgatgaga gtaaacttgt ttttgtgcga gaatacattg agtctcggga cttttttaag
     7381 tatgcccatc gtttgatttt ccaagccatg gtcgatttat ccgatcgtgg tgatgccata
     7441 gatgcaacaa cggttcgtac tatccttgat aatcaaggtg atttacagaa tattggtggc
     7501 ttgtcttact tggttgagat tgtcaattct gtgccaactt ctgctaatgc ggagtattat
     7561 gctaagattg ttgcagaaaa agcaatgcta cgtcgtttaa ttgccaagtt gacagagtct
     7621 gtcaaccaag cttacgaagc gtcacaacca gctgatgaaa ttattgctca ggcagaaaaa
     7681 gggctgattg atgtcagtga aaatgcaaat cgaagcgggt ttaagaacat tcgagatgtg
     7741 ttgaatctca actttggaaa tctggaagct cgctcgcaac aaacgaccga tattacaggt
     7801 attgcgacag gttatcgtga tttggatcat atgacaacag gacttcatga ggaggagttg
     7861 attatcttag cagctcgtcc agcagttggt aagacagcat ttgccttgaa tatcgctcag
     7921 aacattggga ctaagttgga caaaacggtt gctatttttt cactcgaaat gggtgcggaa
     7981 agcttggtag atcgtatgtt agctgcagaa ggcttagtgg agtcacattc tatccgtaca
     8041 gggcaattga cagatgagga gtggcaaaaa tatactattg ctcagggtaa tctagctaac
     8101 gccagtatct atatcgatga tacgccaggt attcggatta cagagattcg ttctcgttct
     8161 cgtaaattgg ctcaagaaac tggaaatctt ggtttgattt tgatagacta tttgcaactt
     8221 atcacgggaa ctggtcgaga aaatcgtcaa caagaagttt ctgaaatttc tcgtcagttg
     8281 aaaatactag ccaaggaatt gaaggttcca gtaatcgctc tgagtcagct ttctcgtggt
     8341 gtagaacaac gtcaggacaa gagaccggtc ttgtctgata ttcgtgaatc tgggtctatt
     8401 gagcaggacg ctgatatcgt agcttttctc tatcgcgatg actactatga acgtggtggt
     8461 gaagaagagg agggtatccc aaataataag gtggaagtta ttatcgagaa aaaccgtagt
     8521 ggagctcgtg gaacagtgga attgattttc caaaaagaat acaataaatt ttcaagtatc
     8581 tcaaagaggg aggcataaga tgtcagatgc atttacagat gtagccaaga tgaaaaaaat
     8641 caaagaagaa atcaaggcac atgagggaca agtcgtagaa atgactttgg agaatggtcg
     8701 taagcgccaa aaaaatagat tgggtaagct aattgaagtt tatccatccc tatttattgt
     8761 ggagtttggg gatgtggaag gagataaaca agttaatgtt tacgttgaat cctttactta
     8821 ctcagatatt cttacagaaa agaatttgat tcattatctt gactaaagtg agaaattttc
     8881 tcactttttc ttttttctcc gaataattta ggtgaaggca atcatcgctt tatattattt
     8941 ttcaaggagg aagaatgaaa attttaccgt ttatagcaag aggaacaagt tattacttga
     9001 agatgtcagt taaaaagctt gttccttttt tagtagtagg attgatgcta gcagctggtg
     9061 atagtgtcta tgcctattcc agaggaaatg gatcgattgc gcgtggggat gattatcctg
     9121 cttattataa aaatgggagc caggagattg atcagtggcg catgtattct cgtcagtgta
     9181 cttcttttgt agcctttcgt ttgagtaatg tcaatggttt tgaaatgccg gcagcttatg
     9241 gaaatgcgaa tgaatgggga catcgtgctc gtcgggaagg ttatcgtgta gataatacac
     9301 cgacgattgg ttccattact tggtctactg caggaactta tggtcatgtt gcctgggtgt
     9361 caaatgtaat gggagatcag attgagattg aggaatataa ctatggttat acagaatcct
     9421 ataataaacg agttataaaa gcaaacacga tgacaggatt tattcatttt aaagatttgg
     9481 atggcggcag cgttgggaat agtcaatcct cagcttcaac aggcggaact cattatttta
     9541 agaccaagtc tgctattaaa cctgaacccc tagctagcgg aactgtgatt gattactatt
     9601 atcctgggga gaaggttcat tatgatcaga tatttgaaaa agacggctat aagtggttga
     9661 gttatactgc ctataatgga agctatcgtt atgttcaatt ggaggctgtg aataaaaatc
     9721 ctctaggtaa ttctgttctt tcttcaacag gcggaactca ttattttaag accaagtctg
     9781 ctatcaaaac tgaaccccta gttagtgcaa ctgtgattga ttactattat cctggagaga
     9841 acgttcatta tgatcaaatt ctcgaaaaag acggctacaa gtggttgagt tatacggctt
     9901 ataacggaag tcgtcgctat atacagctag agggagtgac ttcttcacaa aattatcaga
     9961 atcaatcagg aaacatctct agctatggat cccatagtag ttcaactgtc ggttggaaga
    10021 aaataaatgg tagttggtat catttcaaat caaatggttc taaatcaaca ggatggctga
    10081 aagacggttc tagctggtat tatttgaaat tatctggtga aatgcagaca ggatggttaa
    10141 aggaaaatgg tttgtggtat tatctgggta gttcaggggc aatgaaaaca ggctggtacc
    10201 aggtctctgg taagtggtat tattcttact cttcaggcgc cttagctgtt aatacgacgg
    10261 tggatggcta cagagtaaac agtgatggag aacgagtata gaaaattgga gtaggagaaa
    10321 tttcctgctc ttttctgtaa gcagtttcct tgacattttt cttattttgc gctatcatat
    10381 atacatataa tatatgggag tctgtgtaca gtctgagagg aagtgttaaa cttcgaccgc
    10441 acctgatctg ggtaatgcca gcggagggaa cgatacttag tctaattttg caccttttcc
    10501 atgtatggta aaggtttttc tttttttaaa aaggaaaacg agaagaggag gttcttatga
    10561 aagcaagcat tgccttgcaa gttttacccc tagtacaggg gattgatcgg atagctgtta
    10621 ttgatcaggt cattgcttat ctgcaaactc aagaagtgac gatggtagtg acaccatttg
    10681 aaacggtctt ggaaggggag tttgatgagc ttatgcgcat tctaaaagaa gcgctggaag
    10741 tggcagggca ggaggcagac aatgtctttg ccaatgtcaa aataaatgta ggagagattt
    10801 taagtattga tgagaaactt gagaagtata ctgagacgac acattagtct attgggcttt
    10861 ctcggagtat tgtcaatctg gcagttagca ggttttctta aacttctccc caagtttatc
    10921 ctgccgacac ctcttgaaat tctccagccc tttgttcgtg acagagaatt tctctggcac
    10981 catagctggg cgaccttgag agtggcttta ctggggctga ttttgggagt tttgattgcc
    11041 tgtcttatgg ctgtgctcat ggatagtttg acttggctca atgacctgat ttaccctatg
    11101 atggtggtca ttcagaccat tccgaccatt gccatagctc ctatcctggt cttgtggcta
    11161 ggttatggga ttttgcccaa gattgtcttg attatcttaa cgacaacctt tcccatcatc
    11221 gttagtattt tggacggttt taggcattgc gacaaggata tgctgacctt gtttagtctg
    11281 atgcgggcca agccttggca aatcctgtgg cattttaaaa tcccagttag cctgccttac
    11341 ttttatgcag gtctgagggt cagtgtctcc tacgccttta tcacaactgt ggtatctgag
    11401 tggttgggag gttttgaagg tcttggtgtt tatatgattc agtctaaaaa actgtttcag
    11461 tatgatacca tgtttgccat tattattctg gtgtcgatta tcagtctttt gggtatgaag
    11521 ctggtcgata tcagtgaaaa atatgtgatt aaatggaaac gttcgtagaa ttagaatgtt
    11581 tctgaaaaag aaaagaggaa atcaaaatga agaaaacatg gaaagtgttt ttaacgcttg
    11641 taacagctct tgtagctgtt gtgcttgtgg cctgtggtca aggaactgct tctaaagaca
    11701 acaaagaggc agaacttaag aaggttgact ttatcctaga ctggacacca aataccaacc
    11761 acacagggct ttatgttgcc aaggaaaaag gttatttcaa agaagctgga gtggatgttg
    11821 atttgaaatt gccaccagaa gaaagttctt ctgacttggt tatcaacgga aaggcaccat
    11881 ttgcagtgta tttccaagac tacatggcta agaaattgga aaaaggagca ggaatcactg
    11941 ccgttgcagc tattgttgaa cacaatacat caggaatcat ctctcgtaaa tctgataatg
    12001 taagcagtcc aaaagacttg gttggtaaga aatatgggac atggaatgac ccaactgaac
    12061 ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga ctttgagaag gttgaaaaag
    12121 taccaaataa cgactcaaac tcaatcacac cgattgccaa tggcgtcttt gatactgctt
    12181 ggatttacta cggttgggat ggtatccttg ctaaatctca aggtgtagat gctaacttca
    12241 tgtacttgaa agactatgtc aaggagtttg actactattc accagttatc atcgcaaaca
    12301 acgactatct gaaagataac aaagaagaag ctcgcaaagt catccaagcc atcaaaaaag
    12361 gctaccaata tgccatggaa catccagaag aagctgcaga tattctcatc aagaatgcac
    12421 ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca aaaatacttg tcaaaagaat
    12481 acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc tcgctggaat gctttctaca
    12541 aatgggataa agaaaatggt atccttaaag aagacttgac agacaaaggc ttcaccaacg
    12601 aatttgtgaa ataatgacag aaattagact agagcacgtc agttatgcct atggtcagga
    12661 gaggatttta gaggatatca acctacaggt gacttcaggc gaagtggttt ccatcctagg
    12721 cccaagtggt gttggaaaga ccaccctctt taatctaatc gctgggattt tagaagttca
    12781 gtcagggaga attgtccttg atggtgaaga aaatcccaag gggcgcgtga gttatatgtt
    12841 gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga aatatcattc tgcccctctt
    12901 gattcaaaag gtggataagg cagaagctat ttcccgagcg gataaaattc ttgcgacctt
    12961 ccagctgaca gctgtaagag acaagtatcc tcatgaactt agcggtggga tgcgccagcg
    13021 tgtagcctta ctccggacct acctttttgg gcacaagctc tttctcttag atgaggcctt
    13081 tagcgccttg gatgagatga caaagatgga actccacgct tggtatcttg agattcacaa
    13141 gcagttgcag ctaacaaccc tgatcatcac gcatagtatt gaggaggccc tcaatctcag
    13201 cgaccgcatc tatatcttga aaaatcgccc tgggcagatt gtttcagaaa ttaaactaga
    13261 ttggtctgaa gatgaggaca aggaagtcca aaagattgcc tacaaacgtc aaattttggc
    13321 ggaattaggc ttagataagt agaaaaatag ggagttggtg aagattatcc tttaccagcg
    13381 ccctttttct tttaaaaatg agaaaatttc ggtataatag tcaaacaagg tcaaggttta
    13441 aagagagagg tgggtttgtt atgagattta aaaatacatc ggatcatatt gaggcctaca
    13501 tcaaggcgat tttagatcaa tctggtatcg tggagttgca acggagtcag ttggcagata
    13561 cctttcaggt tgttcctagt cagattaact acgtgatcaa gacacgcttt acggaaagta
    13621 gaggctactt ggttgaaagt aagcgtggtg gcggaggcta cattcgtata ggacggattg
    13681 agttttctag tcatcatgaa atgctccggg agctgcttta ctcgattggt gagcgagtca
    13741 gtcaagaaat ttatgaggat attctccagc ttttggttga gcaggaattg atgaccaagc
    13801 aggagatgaa tttgctagaa tcagtagctt tggatcgcgt tttaggagaa gaagctccag
    13861 ttgttcgagc aaacatgcta cgtcagatca tacaagaggt agatagaaaa gggaagtaag
    13921 atgaactatt caaaagcatt gaatgaatgt atcgaaagtg cctacatggt tgctggacat
    13981 tttggagctc gttatctaga gtcttggcac ttgttgattg ccatgtctaa tcacagttat
    14041 agtgtagcag gggcaacttt aaatgattat ccgtatgaga tggaccgttt agaagaggtg
    14101 gctttggaac tgactgaaac ggactatagc caggatgaaa cctttacgga attgccgttc
    14161 tcccgtcgtt tgcaggttct ttttgacgaa gcagagtatg tagcgtcagt ggtccatgct
    14221 aaggtgctag ggacagagca cgtcttctat gcgattttgc atgatggcaa tgccttggca
    14281 actcgtatct tggagagggc tggtttttct tatgaagaca agaaagatca ggtcaagatt
    14341 gctgcccttc gtcgaaattt agaagaacgg gcaggctgga ctcgtgaaga cctcaaggct
    14401 ttacgccaac gccatcgtac agtagctgac aagcaaaatt ctatggccaa tatgatgggc
    14461 atgccgcaga ctcctagtgg tggtcttgag gactatacgc atgatttgac agagcaagcg
    14521 cgttctggca agttagaacc agtcatcggt cgggacaagg aaatctcacg tatgattcaa
    14581 attttgagcc gtaagactaa gaacaaccct gtcttggttg gggatgctgg tgtcgggaaa
    14641 acagctctgg cccttggtct tgcccagcgt attgctagtg gtgacgtgcc tgcggaaatg
    14701 gctaagatgc gcgtgttaga acttgatttg atgaatgtcg ttgcagggac acgcttccgt
    14761 ggtgactttg aagaacgcat gaataatatc atcaaggata ttgaagaaga tggccaagtc
    14821 atcctcttta tcgatgaact ccacaccatc atgggttctg gtagcgggat tgattcgact
    14881 ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg gaactttgag aacggttggt
    14941 gccaccactc aggaagaata tcaaaaacat atcgaaaaag atgcggctct ttctcgtcgt
    15001 ttcgctaaag tgacgattga agaaccaagt gtggcagata gtatgactat tttacaaggt
    15061 ttgaaggcga cttatgagaa acatcaccgt gtacaaatca cagatgaagc ggttgaaaca
    15121 gcggttaaga tggctcatcg ttatttaacc agtcgtcact tgccagactc tgctatcgac
    15181 ctcttggacg aagcagcagc aacagtgcaa aataaggcaa agcatgtaaa agcagacgat
    15241 tcagatttga gtccagctga caaggccctg atggatggca agtggaaaca ggcagcccag
    15301 ctaatcgcaa aagaagagga agtacctgtc tacaaagact tggtgacaga gtctgatatt
    15361 ttgaccacct tgagtcgctt gtcaggaatc ccagttcaaa aactgactca aacggatgct
    15421 aagaagtatt taaatcttga agcagaactc cataaacgtg tcatcggtca agatcaagct
    15481 gtttcaagta ttagtcgtgc cattcgccgt aatcagtcag gaattcgcag tcacaagcgt
    15541 ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg gtaagaccga gttggccaag
    15601 gctttggcag aagttctctt tgatgacgaa tcagccctta tccgctttga tatgagtgag
    15661 tatatggaga aattcgcagc cagccgtcta aatggagctc ctccaggcta tgtgggttac
    15721 gaagaaggtg gggagctgac agagaaggtt cgcaataaac cctattccgt tctcctcttt
    15781 gatgaggtag agaaggccca cccagatatc tttaatgttc tcttgcaggt tctggatgac
    15841 ggtgtcttga cagatagcaa gggacgcaag gtcgattttt caaataccat tatcattatg
    15901 acatcgaatc taggtgcgac tgcccttcgt gatgataaga ctgttggttt tggggctaag
    15961 gatattcgtt ttgaccagga aaatatggaa aaacgcatgt ttgaagaact gaaaaaagct
    16021 tatagaccgg aattcatcaa ccgtattgat gagaaggtgg tcttccatag cctatctagt
    16081 gaccatatgc aggaagtggt gaagattatg gtcaagcctt tagtggcaag tttggctgaa
    16141 aaaggcattg acttgaaatt acaagcttca gctctgaaat tgttagcaaa tcaaggatat
    16201 gacccagaga tgggagctcg cccacttcgc agaaccctgc aaacagaagt ggaggacaag
    16261 ttggcagaac ttcttcttaa gggagattta gtggcaggca gcacacttaa gattggtgtc
    16321 aaagcaggcc agttaaaatt tgatattgca taaaagaata aaagtatcag catctgacca
    16381 taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc aaactaggca gctagccgca
    16441 ggttgcttaa aacactgttt tgaggttgca gatagagctg acgtggtttg aagagatttt
    16501 cgaagagtat gaaactaaaa cctatagctt ctaaacgatt cgtggttttc accattcaac
    16561 acaaaattca tatgtttatt accctccgtc gtatttgtct tagagcgtgt gtagtagaaa
    16621 aagagcagtc ttatctgaaa tttttattct ttcaaaagag acctgtttct tttttgcatg
    16681 tcaaatccgt tctaactggt atttgaaaaa tcaaactaat actcaatgaa aatcaaagaa
    16741 caaactaggc agctagccgc aggttgctca aaacactgtt ttgaggttgt agatagagct
    16801 gacgtggttt ggagagattt tcgaagagta taagctgcaa gatgaatgat tttcttgtat
    16861 tgacgttgtt gttgacaaaa agtagcggat aaatgaaatc cattccatta tcatagatga
    16921 taggctggta ggaaattttc aaatagcata caggaaatag atgtatggag ttctggtagt
    16981 agaaagggag agagatgaac attttagttg cagatgacga ggaaatgatt agagaaggaa
    17041 ttgcagcatt tctgacagaa gagggttatc atgtcattat ggctaaggat ggacaagagg
    17101 tcttggaaaa atttcaagat ctccctatcc atctcatggt actggattta atgatgccta
    17161 ggaagagtgg ttttgaagtg ttaaaagaaa tcaatcaaaa gcacgatatt cctgtcatcg
    17221 tcttgagtgc tctgggagat gaaactactc agtcacaggt atttgatctc tatgctgatg
    17281 atcatgtgac aaaacctttt tctttggtac tgcttgtcaa gcgtattaag gcgcttatca
    17341 gacgttacta cgtcatagag gatatttggc gatatcagga tgtaacagtg gattttacct
    17401 cttacaaagc acattataaa aatgaagaaa ttgatctcaa accaaaggaa ttactggtac
    17461 taaagtgttt gattcagcat aaaaatcaag ttttaagtag agagcagata ttggaagaaa
    17521 tttcaaaaga tgtagctgat ttaccttgtg atagggtcgt tgatgtctat attcgtactc
    17581 ttcgcaaaaa attagcttta gattgtatcg tgactgtgaa aaatgttggg tataagatta
    17641 gcttatgata aaaaatccta aattattaac caagtctttt ttaagaagtt ttgcaattct
    17701 aggtggtgtt ggtctagtca ttcatatagc tatttatttg acctttcctt tttattatat
    17761 tcaactggag ggggaaaagt ttaatgagag cgcaagagtg tttacggagt atttaaagac
    17821 taagacatct gatgaaatac caagcttact ccagtcttat tcaaagtcct tgaccatatc
    17881 tgctcacctt aaaagagata ttgtagataa gcggctccct cttgtgcatg acttggatat
    17941 taaagatgga aagctatcaa attatatcgt gatgttagat atgtctgtta gtacagcaga
    18001 tggtaaacag gtaacagtgc aatttgttca cggggtggat gtctacaaag aagcaaagaa
    18061 tattttgctt ttgtatctcc catatacatt tttggttaca attgcttttt cctttgtttt
    18121 ttcttatttt tatactaaac gcttgctcaa tcctcttttt tacatttcag aagtgactag
    18181 taaaatgcaa gatttggatg acaatattcg ttttgatgaa agtaggaaag atgaagttgg
    18241 tgaagttgga aaacagatta atggtatgta tgagcacttg ttgaaggtta ttcatgagtt
    18301 ggaaagtcgt aatgagcaaa ttgtaaaatt gcaaaatcaa aaggtttcct ttgtccgtgg
    18361 agcatcacat gagttgaaaa cccctttagc cagtcttaga attatcctag agaatatgca
    18421 gcataatatt ggagattaca aagatcatcc aaaatatatt gcaaagagta taaataagat
    18481 tgaccagatg agccacttat tggaagaagt actggagtct tctaaattcc aagagtggac
    18541 agagtgtcgt gagaccttga ctgttaagcc agttttagta gatattttat cacgttatca
    18601 agaattagct cattcaatag gtgttacaat tgaaaatcaa ttgacagatg ctaccagggt
    18661 cgtcatgagt cttagggcat tggataaggt tttgacaaac ctgattagta atgcaattaa
    18721 atattcagat gaaaatgggc gcgtaatcat atccgagcaa gatggctatc tctctatcaa
    18781 gaatacatgt gcgcctctaa gtgaccaaga actagaacat ttatttgata tattctatca
    18841 ttctcaaatc gtgacagata aggatgaaag ttccggtttg ggtctttaca ttgtgagtaa
    18901 tattttagaa agctatcaaa tggactatag ttttctccct tatgaacacg gtatggaatt
    18961 taagattagc ttgtagacag attagttttt tattaaagtt catatagggt taacataagt
    19021 gtgttattct ttgtatagat aaaagaaagg atactaatat ggtattagcg attattttag
    19081 taacattctt tattcgattg atttttttaa agcgttcgat agagaatgag aaacgaatcc
    19141 ttagcaatgg cgggaaagaa tttggagttg agaatacaaa acgattaact atggctcata
    19201 ttgtttttta tctctcttgc tttgttgagg caatggtgca caagacaatt tttgatggca
    19261 tgggcatggt tggtttggtc ttgcttattt tttctatgct gatgttgatg ttggtgattc
    19321 acttgttggg agatatttgg acagtgaagc ttatgcttgt caataatcac aaatatgtag
    19381 atcatatctt gtttaggaca gtaaaacacc ctaattactt tttaaatatt ttacctgagt
    19441 tgattggctt gaccttgttg agtcatgctt atgtgacttt tgttttagtt tttccagttt
    19501 atgcagttat tttgtatcga cgaatagctg aagaggaaaa gctattacat gaagttataa
    19561 tcccaaatgg aagcataaag agataaatac aaaattcgat ttatatacag ttcatattga
    19621 agtgatatag taaggttaaa gaaaaaatat agaaggaaat aaatatgttt gcatcaaaaa
    19681 gcgaaagaaa agtacattat tcaattcgta aatttagtat tggagtagct agtgtagtag
    19741 ttgctagctt gttcttagga ggagtagttc atgcagaagg ggttagaagt gggaataact
    19801 ccacggttac atctagtggg caagatatat cgaagaagta tgctgatgaa gtcaagtcgc
    19861 atctagaaaa aatattgagt gagatccaaa caaatttaga tagaagtaaa catatcaaaa
    19921 ctgtaaatct aattaacaaa ttgcaagaca ttaagagaac gtatttgtat gaattaaatg
    19981 ttttagaaga taagtcgaaa gctgagttgc cgtcaaaaat aaaagcaaag ttagacgcag
    20041 cttttgagca gtttaaaaaa gatacattac caacagaacc aggaaaaaag gtagcagaag
    20101 ctaagaagaa ggttgaagaa gctgagaaaa aagccaaggc tcaaaaagaa gaagatcacc
    20161 gtaactaccc aaccattact tacaaaacgc ttgaacttga aattgctgag tccgatgtga
    20221 aagttaaaga agcggagctt gaactagtaa aaaaggaagc tgacgaatct cgaaacgagg
    20281 gcacaattaa ccaagcaaaa gcgaaagttg agagtgaaca agctgaggct acaaggttaa
    20341 aaaaaatcaa gacagatcgt gaaaaagcag aagaagaagc taaacgaaga gcagatgcta
    20401 aagagcaaga tgaatcaaag aggcgaaaga gtaggggaaa acgaggagct cttggagagc
    20461 aagcaacacc tgataaaaaa gaaaatgatg cgaagtcttc agattctagc gtaggtgaag
    20521 aaactcttcc aagcccatcc ctgaaaccag gaaaaaaggt agcagaagct gagaagaagg
    20581 ttgaagaagc tgagaaaaaa gccaaggctc aaaaagaaga agatcgccgt aactacccaa
    20641 ccaatactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtgaaa gttaaagaag
    20701 cggagcttga actagtaaaa gaggaagcta aggaatctcg aaacgaggaa aaaattaagc
    20761 aagaaaaagc gaaagttgag agtaaaaaag ctgaggctac aaggttagaa aaaatcaaga
    20821 cagatcgtaa aaaagcagaa gaagctaaac gaaaagcagc agaagaagat aaagttaaag
    20881 aaaaaccagc tccaaaacca gagaagccag ctgaacaacc aaaagcagaa aaaacagatg
    20941 atcaacaagc tgaagaagac tatgctcgta gatcagaaga aaaatataat cgcttgactc
    21001 aacagcaacc gccaaaaact gaaaaaccag cacaaccatc tactccaaaa acaggctgga
    21061 aacaagaaaa cggtatgtgg tacttctaca atactgatgg ttcaatggca acaggatggc
    21121 tccaaaacaa cggttcatgg tactacctca acgctaatgg ttcaatggca acaggttggc
    21181 tccaaaacaa tggttcatgg tactacctca acgctaatgg tgctatggct acaggatggc
    21241 tccaatacaa tggttcatgg tactacctaa acagcaatgg cgctatggct acaggatggc
    21301 tccaatacaa tggttcatgg tactacctaa acagcaatgg tgctatggta acaggatggc
    21361 tccaa
//
LOCUS       DAVDFK010000035        20769 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.35, whole genome shotgun sequence.
ACCESSION   DAVDFK010000035 DAVDFK010000000
VERSION     DAVDFK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.35"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            245..1690
                     /gene="cps4A"
                     /locus_tag="VUR04_001579"
     CDS             245..1690
                     /gene="cps4A"
                     /locus_tag="VUR04_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HET5341453.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTVLVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLATYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKRILLTTTPRDSYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSAPHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1692..2423
                     /locus_tag="VUR04_001580"
     CDS             1692..2423
                     /locus_tag="VUR04_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HET5341454.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLEESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSHHISKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGVKKAKELFVDNPRKIIMDQLI"
     gene            2432..3124
                     /gene="cpsC"
                     /locus_tag="VUR04_001581"
     CDS             2432..3124
                     /gene="cpsC"
                     /locus_tag="VUR04_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET5341455.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFVYSTFVI
                     KPEFTSTTRIYVVNRDQGEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIEDTLQMT
                     LLVVVPNLSKLK"
     gene            3134..3817
                     /gene="cpsD"
                     /locus_tag="VUR04_001582"
     CDS             3134..3817
                     /gene="cpsD"
                     /locus_tag="VUR04_001582"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET5341456.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLLDGDTRNSVISGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNTENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GSYGSYGKK"
     gene            3833..5200
                     /locus_tag="VUR04_001583"
     CDS             3833..5200
                     /locus_tag="VUR04_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET5341457.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVREAELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIYEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRSDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYVQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     REGAK"
     gene            5229..6401
                     /locus_tag="VUR04_001584"
     CDS             5229..6401
                     /locus_tag="VUR04_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HET5341458.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDSNIQYYVACMR
                     ENSAKSGIMDDQFEHNGAICFNIDVPNIGPARAIAYDIAAVNKAIELAKKNKDEAPIF
                     YILACRIGPFISGLKKKIRAIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIQEDYKQYQPKTTYIAYGTDTTPSILKAEDAKVRDWYQEKGVSEN
                     GYYLVVGRFVPENNYEAMIREFIKSKSKKDFVLITNVEQNKFYDQLLQDTGFDKDPRV
                     KFVGTVYDQELLKYIREYAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELARVIEEVEGFDQAAITDLDFKSSQRILSAFTWEKIVSDYEEVFKG"
     gene            6405..7553
                     /locus_tag="VUR04_001585"
     CDS             6405..7553
                     /locus_tag="VUR04_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5341459.1"
                     /translation="MKRILYLHAGAEMYGADKVLLELIKGLDSKEFEAHVILPNDGVL
                     VKALRQVGAQVSVLDYPILRRKYFNPKGILEYLKSYRRYSQKISQYVRENGIDLVHNN
                     TTAVLEGIYLKRKVKLPLIWHVHEIIVKPKAISDFINFLMGRYADKIVTVSQAVSSHV
                     KQSPFIKEGQVQVVYNGVDNAVYHPMQASTVREQFAIPEESLVIGMVGRVNAWKGQGD
                     FLEAVAPILEQNPNSIAFLAGSAFAGEEWRVEELESTIAKSSVASQIKRIDYYEHTTE
                     LYNMFDIFVLPSTNPDPLPTVVLEAMACGKPVVGYRHGGVCEMIKEGKNGLLATPNKP
                     AELSKAIQELADNIEKREQLGSASFQRQKEFFSLESYIRNFSELYKKY"
     gene            7591..8232
                     /locus_tag="VUR04_001586"
     CDS             7591..8232
                     /locus_tag="VUR04_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HET5341460.1"
                     /translation="MNTETIKNKLKPIVYPIINFIPRRRLKNKNFTIICDNCWAGKVY
                     QELGLPYQTPFVGMFVFSPDYIKMLKNLKHYLSGNIPLTFVKESKYVKDFDNAYPLAL
                     LDDIELHFLHYADEEEATQKWNRRLERIHWDNLYFKFNDNDACTYELMKEFEELPYKS
                     KVIFSSRNYSGLPSLVHFKSAEKQGHVGIDLKTYHRYFNCVTWLNKGGEDLTK"
     gene            8229..9191
                     /locus_tag="VUR04_001587"
     CDS             8229..9191
                     /locus_tag="VUR04_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341461.1"
                     /translation="MKKIRIIIPYFGKLPTFFPYFLLTAKRNQKIDFLVYTDQKVDEF
                     AMLNAKNIEFVTLSFDELREKVQSKFDFKISLKTPYKFCDYRPAYGLIFEEELKGYDY
                     WGFCDTDVLLGDIYQFLEEHSFFENDYARYGLFGHLQIFKNLREVNHIFMSGQGSDYR
                     LDYHNVYTSEQSFIFDESEGIQKLFEKCHFKQLQDKFFDDIDISHFSFREYGENKSKR
                     YYFWSEENGLESINLINDDIVVKRPLYAHFQKRMIKCPDFKLVDSFYVIPNQLVIGEK
                     ISKQELVEVTRNKFYWEYVKSTMLKKLKKEKWTFEFIRHKLRMK"
     gene            9202..9461
                     /locus_tag="VUR04_001588"
                     /pseudo
     CDS             9202..9461
                     /locus_tag="VUR04_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294419.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9480..9629
                     /locus_tag="VUR04_001589"
     CDS             9480..9629
                     /locus_tag="VUR04_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HET5341462.1"
                     /translation="MYFKFNNNDICTYELMKEFEELPYKSKVIFSSKNYSDLPSLIHF
                     KSAEK"
     gene            10053..11054
                     /locus_tag="VUR04_001590"
     CDS             10053..11054
                     /locus_tag="VUR04_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET5341463.1"
                     /translation="MIIQNILLTIVIPVYNVEKYLKRCIDSVISQEWDKYEVILVNDG
                     STDASPNICEEYAQKYHFISVIHKENGGLSETRNTGLSHANGKYVFFLDSDDWITKDM
                     FRNLSKMIMEQNYDILQFGMQMFHSEREELKNVQCKEKNFNSSDAFKNMLSVEGITSF
                     ATDKIYKRELFEKNGIEFPIGYFYEDLGTVYKLILSAKKIYLTTQVYYCYFIGNDAAI
                     TKQWSEKKISDVYKFHKKIFNVSSLMVSDDIFLSKSYYNNGLVYLLMKLYEENQEDTQ
                     LFRLILAELDANIVPIKYLRNYPNFLKYVFYRIRLLKLIVILKLTLTKIKKWNQKKH"
     gene            11033..11971
                     /locus_tag="VUR04_001591"
     CDS             11033..11971
                     /locus_tag="VUR04_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET5341464.1"
                     /translation="MESKKTLIIFEQIDTFEQFLERNIIFNNVDIFTPYKKVSNVFMH
                     NFRAIAKRLPGFLFHNWWLEEWSRKLPDYTNIVVFDNAISLKLLEYIDAHKTRSSKLK
                     LWLWNVPNKQVNYLNSNYDVYCFDKTYSENYNLKFVEQFYVLGSTKKRDILDIEYDFY
                     FIGADKGRLPKLKSLAKQIVLNNYSYRFDVFSVKKQYFDSEFEGIQVIDTLLPYDEVL
                     DNILASNVIVELNKKGQDGLTLRAMESIFYKKKLITNNKKIINYDFYHPNNILVWEEG
                     KDIKLDEFIQKPYVQLEKDIIDRYSFSNWLSKITEI"
     gene            11981..13048
                     /locus_tag="VUR04_001592"
     CDS             11981..13048
                     /locus_tag="VUR04_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5341465.1"
                     /translation="MRITFCLPEISTVPTGGYKIIFEYANRLSERGHEITLVFLTNNV
                     WNRVTKNCKIKSIVGNIRGKKNPSWFKLKPTIRKIMTPYLDGRDFPEADFIFATAVTT
                     ANIVKEMPEKYGKKCYLIQGFETWLLPESKVIETYNYGFLNITVSKWLCDIVQSYTET
                     PVFCVSNPIDTEIFYLLNPIEKRNPFHLGMLYHEGEHKGISYAIDAIKKVKKIYPEIE
                     VNIFGVPSRPVFLPEYFNYTQQATQQELQKIYNDTSIFLCATIDEGFGLTGAESMACG
                     CALVSTAYSGVFEYAIDGENALLSPIKDSVSLATNIIKLIRNHDLRLSIATQATKDMK
                     KRGWEKTTLKLENILSEFTNF"
     gene            13065..14480
                     /locus_tag="VUR04_001593"
     CDS             13065..14480
                     /locus_tag="VUR04_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HET5341466.1"
                     /translation="MIIKLDKQKCYFIMLLLLMCVVQLTASVSMGVISIALTVLPILW
                     NLNNPSKLLFSQILYLFQFQFYVSYLSFPLGISFICDIINLFLLFNIFKDSKLLQWEL
                     RNINLKTIIFVWVLFFLIGIFSNFLYDLNIALIVWSLRNYIRFIIFFISCCLYIDKYS
                     INLGEYLIKLFYWFNIFFTSFQYFVLLKSGDFLGGIFGNELGISNTYLHILLILILIL
                     SVVNYVSDNSSLVILTSYIVSTLYVAALSELKIIFVELPIIIILTLLFKRLGIKILLK
                     IISITCIVVVALAISIPILYELFPIFDNFFKLEKLFGYSTGNYSTSSDFGRLSSIVQI
                     ISTIFYGDVWQTLFGIGLGEAEISKIPIFSGSFYYNYEYTHYYLFTLSYVFIENGFIG
                     LFLFMFMPIYLALKMIFERGTSKYDLLLIVLSISLFMLLLYNNTMRSEIYYLYLFVLS
                     WGVAINRGNGGCYENNKKLCL"
     gene            14452..15873
                     /locus_tag="VUR04_001594"
     CDS             14452..15873
                     /locus_tag="VUR04_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HET5341467.1"
                     /translation="MKTIKNYAYKSFYQLFLIIVPFITIPYVSRILGAELIGINSYTN
                     TIISYFVLIANLGILIYGNRTIAYHRESIEERSKKFWEIVSIKLLVAIVAYVIFIIFL
                     FFYSKYSWVFVIQSVQIIATAFDISWLFDGVEDFKRTVVRNFLVKIISIILIFTFVKS
                     TEDFDKYIWITVGSTLMGNLTLWSYLHHYIIKIPIKSLKLSEHLVPILTLFIPQIASI
                     VFMSINKILLGNISTISQAGYFENADKVIRILLALVSSIGVVVFPKVAHAYRSGDMKR
                     VLGLTYMTFDAVNIITIPIVVGIVSISPTFSSIFFGTEFQGIDKVLSVLVLELIFMGY
                     TSVLGSQYLIVTGQTYFLSISVFLGIFSTVISSFFFIPIYGALGSAISSVIGEASIMI
                     GEIYLLRNQVDFYYLYRDVPKYMIASAVMYISISSLNYFISSPFVSLLSSIAMGAVTY
                     VTVVLLLCPRIVIKLLNKNTRFF"
     gene            15999..16868
                     /gene="rfbA"
                     /locus_tag="VUR04_001595"
     CDS             15999..16868
                     /gene="rfbA"
                     /locus_tag="VUR04_001595"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET5341468.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGSGLSKMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            16869..17462
                     /locus_tag="VUR04_001596"
     CDS             16869..17462
                     /locus_tag="VUR04_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET5341469.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            17475..18524
                     /gene="rfbB"
                     /locus_tag="VUR04_001597"
     CDS             17475..18524
                     /gene="rfbB"
                     /locus_tag="VUR04_001597"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET5341470.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            18590..19441
                     /gene="rfbD"
                     /locus_tag="VUR04_001598"
     CDS             18590..19441
                     /gene="rfbD"
                     /locus_tag="VUR04_001598"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HET5341471.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVNPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            19504..20598
                     /gene="glf"
                     /locus_tag="VUR04_001599"
                     /pseudo
     CDS             19504..20598
                     /gene="glf"
                     /locus_tag="VUR04_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239785.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         6836 a         3069 c         4108 g         6756 t
ORIGIN      
        1 aagattatac cacattgtgt accatattga aactagaata gtacatccct gcttctaaaa
       61 cattgttaga aatcgatgta actgtcctga tcgttttgtc atgttcttat ttcattttac
      121 tatatttttg gttcgcggga agtctactaa gatacttaaa gatgcagata gtgaaaataa
      181 aggtgtagac attaccgtaa aaaagtgata taatcgtaca atgttcaagg tataggtgtt
      241 aatcatgagt agacgtttta aaaaatcacg ttcacagaaa gtgaagcgaa gtgttaatat
      301 cgttttgctg actatttatt tattattagt ttgtttttta ttgttcttaa tctttaagta
      361 caatatcctt gcttttagat atcttaatct agtggtaact gtgttagtcc tactagttgc
      421 cttggtaggg ctactcttga ttatctataa aaaagctgaa aagtttacta tttttctgtt
      481 ggtgttctct atccttgtca gctctgtgtc gctctttgca gtacagcagt ttgttggact
      541 gaccaatcgt ttaaatgcga cttctaatta ctcagaatat tcaatcagtg tcgctgtttt
      601 agcagatagt gagatcgaaa atgttacgca actgacgagt gtgacagcac cgactgggac
      661 tgataatgaa aatattcaaa aactactagc tgatatcaag tcaagtcaga ataccgattt
      721 gacggtcaac cagagttcgt cttacttggc aacttacaag agtttgattg caggggagac
      781 taaggccatt gtcctaaata gtgtctttga aaatatcatt gagtcagagt atccagacta
      841 cgcatcgaag ataaaaaaga tttataccaa gggattcact aaaaaagtag aagctcctaa
      901 gacgtctaag aatcagtctt tcaatatcta tgttagtgga attgacacct atggtcctat
      961 tagttcggtg tcgcgatcag atgtcaatat cctgatgact gtcaataggg atacgaagag
     1021 aatccttctt acaacaactc ctcgagattc atatgttcct attgctgatg gtggaaataa
     1081 tcaaaaagat aaattaaccc atgcgggcat ttatggagtt gattcgtcca ttcacacctt
     1141 agaaaatctc tatggagtgg atatcaatta ctatgtgcga ttgaacttca cttctttctt
     1201 gaaaatgatt gacttattgg gaggggtaga tgttcataat gatcaagagt tttcagctcc
     1261 acatgggaag ttccatttcc cagtagggaa tgtccatcta gactctgagc aggctctagg
     1321 ttttgtacgt gaacgctact cactagccga tggagaccgt gaccgtggtc gcaaccaaca
     1381 aaaggtgatt gtggctatcc ttcaaaaatt aacgtcaacc gaagcactga aaaattatag
     1441 tacgatcatt aatagcttgc aagattctat ccaaacaaat atgccacttg agactatgat
     1501 aaatttggtc aatgctcagt tggaaagtgg agggaattat aaagtaaatt ctcaagattt
     1561 aaaagggaca ggtcggatgg atcttccttc ttatgcaatg ccagacagta acctctatgt
     1621 gatggaaata gatgatagca gtttagctgt agttaaagca gctatacagg atgtgatgga
     1681 gggtagatga aatgatagat atccattcgc atatcgtttt tgatgtagat gacggtccca
     1741 agtcaagaga ggaaagcaag gctctcttgg aagaatccta caggcagggg gtgcgaacca
     1801 ttgtctctac ctctcaccgt cgcaagggca tgtttgaaac tccagaagag aagatagcag
     1861 aaaactttct tcaggttcgg gaaattgcaa aagaagtagc agatgattta gtcatcgctt
     1921 atggagcaga gatatactat actctggatg ctctagaaaa gctagaaaaa aaagaaattc
     1981 ctacccttaa tgatagtcgt tatgctttga ttgagtttag catgcatact tcctatcgtc
     2041 agattcatac gggattgagc aatattttga tgttgggaat cacgccagta attgctcata
     2101 ttgaacgtta tgatgcttta gagaataacg aaaaacgtgt tcgtgaactg attgatatgg
     2161 ggtgctatac tcagataaat agtcatcata tttcaaaacc taagttcttt ggtgaaaaat
     2221 ataaattcat gaaaaagaga gctcggtatt ttttggaacg tgatttagtt catgtagttg
     2281 caagtgacat gcacaattta gacagcagac ctccatatat gcaacaggca tatgatatca
     2341 ttgctaagaa atatggagtg aaaaaagcga aagaactttt tgtagataat cccagaaaaa
     2401 ttataatgga tcaattaatt taggagaaaa tatgaaggaa caaaacactt tggaaatcga
     2461 tgtattgcaa ctattcagag ctttatggaa aagaaagttg gttattttat tagtggcaat
     2521 tataacttct tcagttgctt ttgtctacag tacttttgtt atcaaacctg agtttactag
     2581 tacgactcgg atttatgtag ttaaccgtga tcagggagag aagtctggtt taaccaatca
     2641 agacttgcag gcaggatcat acttggttaa agactatcgt gaaattatcc tatcgcagga
     2701 tgttttggag gaagttgttt ctgatttgaa actagatttg acgccaaaag gtttggctaa
     2761 taaaattaaa gtaacagtac cagttgatac ccgtattgtc tctgtttcag ttaatgatcg
     2821 agttcctgaa gaggcaagcc gtatcgctaa ctctttgaga gaagtagctg ctcaaaaaat
     2881 tattagtatt actcgtgttt ctgatgtgac aacactggag gaggcaaggc cggcgatatc
     2941 accgtcttcg ccaaatatta aacgcaatac actaattggt tttttggcag gggtgattgg
     3001 aactagtgtt atagttcttc ttcttgaact tttggacact cgtgtgaaac gtccggaaga
     3061 tatcgaagat acactgcaga tgacactttt ggtagttgta ccaaacttga gtaagttgaa
     3121 ataggagaga ggaatgccga cattagaaat agcacaaaaa aaactggagt tcattaagaa
     3181 ggcagaagaa tattacaatg ccttgtgtac aaatatacag ttgagcggag ataaactaaa
     3241 agtaatttcc gttacttctg ttaaccctgg ggaaggaaaa acaactactt ccgtaaatat
     3301 agcaaggtcg tttgcgcgtg caggctataa aactcttttg ctcgatggcg atactcgaaa
     3361 ttcagttata tcaggatttt ttaaatctcg tgaaaaaatt acagggctaa cagaattttt
     3421 atctgggaca gctgatttat ctcacggttt atgtgataca aatactgaaa atttatttgt
     3481 agttcaatcg ggatctgtat caccaaaccc tacagccttg ttacaaagta aaaattttaa
     3541 tgatatgatt gaaacgttgc gtaaatattt tgactatatc attgttgata cagcacctat
     3601 tggaattgtt attgatgcgg caattatcac tcaaaagtgt gatgcgtcca tcttggtaac
     3661 agcaacaggt gaggtgaata aacgtgatgt ccaaaaagcg aaacaacaat tagaacaaac
     3721 agggaaactg ttcctaggag ttgttttaaa taaattggat atctcggttg ataagtatgg
     3781 agtttacggt tcctatggaa gttatggtaa aaaataattt aggaaaaatt ttatggatga
     3841 aaaaggattg aaaatttttc tggcagtatt acagagtatt attgtcattt tattggttta
     3901 ttttcttagc tttgttagag aggcagaact tgaacgttct tcgatggtta tactatacct
     3961 tctccacttt tttgtattct attttagttc ctatggtaac aattttttta aaagagggta
     4021 cctagttgag tttaatagta ctataagata tatttttttc tttgcaatag ctataagtgt
     4081 attaaacttt tttatagcgg aacggtttag tatctctaga agaggaatgg tatacttctt
     4141 aactttagaa ggaatatcct tatacttgtt aaatttctta gtaaagaaat attggaaaca
     4201 tgtgtttttt aatctaaaaa atagcaagaa aattttactg ttaacagtaa cgaaaaatat
     4261 ggaaaaagtt cttgataaac tgctagaatc cgatgaactt tcatggaagt tggtagcagt
     4321 aagtgttttg gataaatctg attttcaaca tgataaaata cctgtaattg aaaaggaaaa
     4381 aattattgaa tttgcaacgc atgaagttgt ggatgaggtg tttgtcaatc ttccaggaga
     4441 gagctacgat attggagaaa ttatctctag gtttgagaca atggggatag atgtaactgt
     4501 aaatcttaaa gcatttgata agaatttggg tcgcaataaa caaatttatg agatggtagg
     4561 attgaatgta gtcactttct ctacaaattt ttataaaact agtcatgtga tttcaaagag
     4621 aattctcgat atttgtggtg ccactattgg ccttattctt tttgctatag ctagtctagt
     4681 tttagttcca ttgattcgta aagatggcgg accagctatt tttgctcaaa ctcgtatagg
     4741 gaaaaatggt cgacatttta ccttttataa attccgttcg atgcggagcg atgctgaagc
     4801 tatcaaagaa cagttgatgg atcaaaatac gatgcaaggt ggtatgttta agatagacaa
     4861 cgatcctcgt gttacaaaaa ttggtcgctt tattcgtaaa accagtttag atgagttacc
     4921 ccagttttgg aatgtcttta taggagatat gagtttggtg ggaacacgtc cacctacagt
     4981 agacgagtat gttcagtata ctccagaaca gaaacgtcga ctcagcttta aacctggtat
     5041 tacaggttta tggcaggtta gcggccgtag taaaataacc gattttgacg atgttgtaaa
     5101 attagatgtg gcttatattg ataattggac aatctggaaa gatattgaaa tattgttaaa
     5161 gaccgtcaaa gtggtattta tgagagaagg ggcgaagtga tttctgccct caacctgtta
     5221 ggagagaaat gaaacagtca gtttatatta ttggttcaaa ggggattcct gctaagtatg
     5281 gaggatttga aacctttgtt gaaaaattaa ccgaatatca aaaagacagc aacatacaat
     5341 actatgttgc ttgtatgcgt gaaaattcag ctaaatctgg catcatggat gatcagtttg
     5401 agcacaatgg agccatttgt ttcaacatcg atgtacccaa tattggacca gctcgtgcca
     5461 tcgcttacga tattgcagcg gtcaacaaag ctattgaatt ggctaagaaa aataaggacg
     5521 aagctcccat tttttacatt ctagcttgtc gcattggtcc ttttatttct gggcttaaga
     5581 aaaaaattcg tgccatcgga ggccggttgt tggtaaatcc tgatggtcat gaatggttgc
     5641 gagcaaagtg gagtttacca gttcgtaagt attggaaatt ttcagagcag ctcatggtca
     5701 aacatgcaga tttactggtc tgtgacagta aaaacattga aaaatatatc caagaggatt
     5761 ataagcagta ccaaccaaag accacctata ttgcctatgg aacggatact actccttcaa
     5821 tcctgaaagc agaagatgcc aaagttcggg attggtatca ggaaaaagga gttagcgaaa
     5881 atggctatta tctagtggtg gggagattcg ttcctgaaaa taactacgaa gcaatgattc
     5941 gtgaatttat caagtccaag tccaagaagg actttgtcct catcacaaat gtggagcaga
     6001 ataaatttta cgaccagttg ttacaggata ctggttttga taaagatcct agggttaaat
     6061 ttgttgggac tgtctatgac caagagttgc tcaagtacat ccgtgagtat gcctttgcct
     6121 atttccatgg gcatgaggtt ggagggacca acccttctct attggaagcc ctagcatcca
     6181 caaaactgaa tttgttgcta gatgttggct ttaaccgtga ggttggtgaa gacggggcca
     6241 tttattggaa aaaagatgag ttggctcgtg tcattgagga agtagaagga tttgatcagg
     6301 cagcaataac tgacttggat ttcaagtcaa gccaaagaat cctctcagct ttcacatggg
     6361 aaaagattgt gtcagattat gaagaagtgt ttaaaggata gggaatgaaa cggattttat
     6421 acttgcatgc tggtgcagaa atgtatggag cagataaggt tttattggaa ttgatcaaag
     6481 gattggattc caaagaattt gaagctcatg tcatcctgcc aaatgatggt gttttagtca
     6541 aggccttgcg tcaagttggg gctcaggtca gtgtgttgga ttatccgatt ttacgtagaa
     6601 aatactttaa tcctaagggg attttagaat atctgaaatc ctatcggcgc tactctcaaa
     6661 aaatttccca atatgtgcgt gagaatggga tagatcttgt tcataacaat acgacagccg
     6721 ttctggaagg aatctatctc aagagaaaag taaaactccc cttaatctgg catgttcatg
     6781 agattattgt caagcccaag gctatttcag attttatcaa ctttttgatg gggcgatatg
     6841 cagataagat cgtaacagta tctcaagctg tttccagcca tgtcaaacaa tctcctttta
     6901 tcaaagaagg tcaggtacag gttgtatata acggagtgga caatgctgtc tatcatccca
     6961 tgcaagcaag cacagtgcgt gaacaatttg ctattccaga agaatctctt gtcattggta
     7021 tggtaggccg cgtcaacgct tggaagggac agggagattt tctagaagca gtggcgccga
     7081 ttttggagca gaatcccaat tctatcgctt ttctggcagg aagtgccttt gcgggagaag
     7141 agtggcgagt tgaagaactc gaatctacga ttgccaaatc aagtgtagcc tcacaaatca
     7201 aacgaattga ctattatgag catacgactg agctttataa tatgtttgat atctttgtct
     7261 tgccaagcac caatcccgat cccctaccga cagtggtact agaggcgatg gcatgtggca
     7321 aaccagtagt tggctatcgg catggtggtg tctgtgaaat gattaaggag ggcaaaaacg
     7381 gtctcctagc cactccaaat aagcctgcag aattgtctaa ggctattcaa gaattggctg
     7441 acaatatcga gaaaagagaa cagttaggaa gtgcatcttt ccaacgtcaa aaagaattct
     7501 tttcgttgga aagttatatt cggaatttct cagagctata taaaaaatac taagatgaat
     7561 actaagatga atactaagat gaatactaag atgaatactg aaacaattaa gaataaatta
     7621 aaaccaatcg tttatccaat tatcaatttt atccctagac gaagactcaa gaataaaaat
     7681 tttacaatca tttgcgacaa ttgttgggca ggaaaagtct atcaggaatt gggcttgcct
     7741 tatcaaactc catttgtagg tatgtttgtc ttttctcctg actacatcaa aatgctcaag
     7801 aatttaaaac actatttgag tggaaatatc cctttgacat ttgttaagga atcaaaatat
     7861 gtcaaagact ttgataatgc ctatcccctg gctcttttag acgatatcga attgcatttc
     7921 ttacattatg cagatgagga agaagcaact caaaaatgga accgtcgttt agaaagaatt
     7981 cattgggata atttgtattt caagttcaat gataatgatg cctgtactta tgaattgatg
     8041 aaagagtttg aagaacttcc gtacaagagt aaggttatct tctcttcgag aaattacagt
     8101 ggtttacctt ccttagttca tttcaaatca gctgaaaagc aaggacacgt tgggattgat
     8161 ttgaaaactt atcaccgcta ttttaattgt gttacttggt tgaataaggg tggggaggat
     8221 ttaactaaat gaaaaaaata agaattatta ttccttattt tgggaaacta ccaacctttt
     8281 ttccttattt tttattaact gctaaacgta atcaaaaaat tgatttctta gtttatacgg
     8341 atcaaaaggt ggatgaattc gctatgttaa atgctaaaaa tatagaattt gtaactcttt
     8401 cttttgatga gttaagagaa aaagttcagt ctaagtttga ttttaaaatc tctctcaaaa
     8461 caccttataa attttgtgac tatagacctg cttatgggct tatctttgaa gaagaattaa
     8521 agggttatga ttactggggt ttttgtgaca cagatgtctt actaggtgat atttatcaat
     8581 ttcttgaaga gcatagcttt tttgagaacg actatgctcg atatggtctt tttggtcatc
     8641 ttcaaatttt taagaattta agagaagtta atcatatttt tatgtctggg caaggttcag
     8701 actatcgatt agattatcac aatgtctata ctagtgaaca aagttttatt tttgatgaat
     8761 cagaaggtat ccaaaagctt tttgaaaaat gtcatttcaa acaactgcaa gataagtttt
     8821 ttgatgatat tgatattagt catttctcat ttcgggaata tggcgaaaat aaatcgaaac
     8881 gctattattt ttggtctgaa gaaaatggtt tggaatcaat aaatttaatc aatgatgata
     8941 tagtggttaa gcgtcctcta tacgcacatt tccaaaagag aatgattaaa tgccctgact
     9001 ttaaactagt cgattcattt tatgttatac caaatcaatt agttattgga gagaaaattt
     9061 ctaagcaaga gctagtagag gtgacaagaa ataaattcta ttgggaatat gttaaatcaa
     9121 caatgttaaa gaaattaaaa aaagaaaaat ggacatttga atttattcgt cataaattaa
     9181 ggatgaaatg agcttagtat tatggctttt cctattgatt ttgttgtatg ctgaattgac
     9241 gaacacgatc ctgattggag ggctaaaaat agcaagtatg actctgcttt tacaacatct
     9301 gaaaataata cgaatttcga tgaagcatac tgttagtgga gaacgtttaa gttttggtta
     9361 gagagataga aaaatttgct ccttgggtga ataaagttta tcttgttaca gaaaatcaaa
     9421 aaccggtctg gttgactatt aatagtgata agttatatta attgaacatt tgggatgatt
     9481 tgtatttcaa gttcaataat aatgatattt gtacttatga attgatgaaa gaatttgaag
     9541 agcttccata caagagtaag gttatcttct cttcaaaaaa ttacagtgac ctaccttcct
     9601 tgattcattt taaatcagcc gagaagtaag cgcatgttgg aattgatttg aaaacttatc
     9661 accgctattt tgatgttgtt agttggataa accaagatag tgtatagttc actaaataat
     9721 taaatacaga ttatttcaat gtttctataa gttcaaaatt taattagaaa ctatagagga
     9781 atccatcttt aagattatta tttataagtg agcaatatta actggagtca atgatttaac
     9841 agaaaattca ggtgctagtc agtcattgat tatgtttatg aatataataa tgaaaggaat
     9901 ttctaatttt acaagaattg aatcttgtat cgaaatacat tagttctata aaaatgaatt
     9961 aattaaaaaa ttagagattt acacaatatc agttctacta agattatgca ataaaaagtt
    10021 tctaaaaaat tatttactaa gtgaaggatg atatgattat acaaaatata ttgctaacaa
    10081 ttgtaatacc agtatataat gttgaaaaat atttgaaacg ttgtattgat agcgtcattt
    10141 ctcaggaatg ggataaatat gaagttattc tagtaaatga tggcagtaca gatgcttcac
    10201 ccaatatttg tgaagagtat gcccagaagt atcattttat ttctgttatt cataaggaaa
    10261 atggtggact atcagagact cgtaatacag gtctttctca tgcgaatgga aaatacgtat
    10321 tttttcttga ttctgatgat tggattacaa aagatatgtt tcgaaattta agtaaaatga
    10381 ttatggaaca aaattatgat attttgcaat tcggaatgca aatgtttcat tctgaaagag
    10441 aagagttgaa aaatgtacaa tgcaaagaaa aaaactttaa ttcttcagat gcatttaaaa
    10501 acatgttaag tgttgaaggg attacaagtt ttgctacaga caaaatatat aaaagagaat
    10561 tgtttgagaa gaacggaata gagtttccta taggatattt ttacgaagat ttaggaacgg
    10621 tttataaatt aattttatct gctaaaaaaa tttatttaac aacacaagtg tattattgtt
    10681 attttattgg gaatgatgcg gctattacca aacagtggtc tgaaaaaaaa attagtgatg
    10741 tgtataaatt tcataaaaaa atttttaatg tttcatctct tatggtttca gatgacatct
    10801 tcctgtctaa atcctattat aataatggtc tggtttatct tttaatgaaa ttgtatgaag
    10861 aaaatcagga agacactcaa ctttttaggt tgatacttgc agaactggat gcaaacatag
    10921 ttcctataaa atatttgcga aattatccta attttttgaa atatgtattt tatcgcattc
    10981 gattattgaa attaattgta atattgaaat taactttaac aaaaataaaa aaatggaatc
    11041 aaaaaaaaca ttaataatat ttgaacaaat agatacattt gaacaatttt tagaacgtaa
    11101 tataattttt aataatgtag acatatttac accgtacaaa aaagtttcga atgtttttat
    11161 gcacaatttt agagcaattg caaaacgatt acccggattt ttattccata attggtggtt
    11221 agaagaatgg tctagaaaat taccggatta tactaatata gtagtatttg acaatgctat
    11281 ttcccttaaa ttattagagt atatagatgc acataagact cgtagttcaa agttgaaatt
    11341 atggttatgg aatgttccga ataagcaagt gaattatttg aattcgaatt atgatgttta
    11401 ttgctttgat aagacatatt ctgaaaacta taatttaaaa tttgtagaac aattctatgt
    11461 attaggttcg actaagaaaa gagatatatt ggatattgag tatgattttt attttattgg
    11521 tgcagataaa ggaagattgc caaaattaaa aagcttagct aagcagatag ttttaaataa
    11581 ttatagttat cgatttgacg tttttagtgt aaaaaaacag tatttcgatt ctgagtttga
    11641 gggaattcaa gttatagata cattactccc ttatgatgaa gtcttggata acatactagc
    11701 ttcgaatgtt attgttgagt taaataaaaa gggacaggat ggtctaaccc ttagagcaat
    11761 ggaatccatt ttttataaaa aaaaattaat aacaaataat aaaaaaatta ttaactatga
    11821 tttttatcac ccaaataata ttttagtttg ggaggaagga aaagatatca aattagatga
    11881 gtttattcaa aagccatatg ttcaattaga aaaagatatt attgaccgtt attcttttag
    11941 taattggtta agtaaaatta cagaaattta ggagttaaat atgagaataa ctttttgtct
    12001 acctgagata agcactgttc ctacgggagg atataaaatt atttttgagt acgcaaatag
    12061 gttgtctgaa cgaggtcatg agataaccct tgttttttta accaataatg tatggaacag
    12121 agttactaag aattgtaaaa tcaaatcaat tgtaggcaat atacgtggca aaaaaaatcc
    12181 aagttggttt aaactgaaac caactattcg taaaataatg actccttatt tagatgggag
    12241 agattttcct gaagcagatt ttatatttgc tactgcggtt acaactgcta atattgtaaa
    12301 agaaatgcca gaaaaatatg ggaaaaaatg ttacctaatc caaggttttg aaacatggct
    12361 tcttccagaa agtaaagtta ttgaaactta taattatgga ttccttaata ttacagtatc
    12421 taagtggtta tgtgacatag tccaatctta tacagagact ccagtttttt gtgtatctaa
    12481 tccgattgat acagaaattt tttatttgct aaatcctata gagaaacgaa acccatttca
    12541 tctaggtatg ttatatcatg aaggagagca taaaggaatc tcttatgcga tagatgcaat
    12601 taagaaagtt aagaaaattt atccggaaat agaggttaat atttttggag ttcctagtag
    12661 accagtattt ttaccagaat attttaatta tactcaacaa gctacacaac aggaattaca
    12721 aaagatatac aacgatacgt ctattttttt gtgtgcaaca attgatgaag gctttggttt
    12781 gacaggagca gagagtatgg cttgtggctg tgcgttagtc tcaacagcct atagtggtgt
    12841 atttgaatat gcaattgatg gcgagaatgc acttttatct ccgataaaag atagtgttag
    12901 tttggcaaca aacataataa aattgattag aaatcatgat ttgcgcttat ccatagcaac
    12961 gcaagcaact aaagatatga aaaagagagg atgggagaaa actactttaa aattagaaaa
    13021 tattttaagt gaatttacta atttttaaag atgttttaat atcaatgatt ataaaactag
    13081 ataaacaaaa atgttatttt attatgttac ttttattgat gtgcgtagta cagttgactg
    13141 caagtgtttc aatgggagta ataagtatag ctctaacagt attaccaata ttgtggaatt
    13201 taaataatcc atccaaatta ttattttcac agattcttta tttgtttcag ttccaattct
    13261 atgtaagtta tttatcattt ccgttaggaa tttcctttat ctgtgatatt attaatttat
    13321 ttttgttatt caatattttt aaagattcca aactattaca gtgggaatta cggaatatta
    13381 atttaaaaac aattattttt gtttgggtct tgtttttttt gataggtatt ttttcaaatt
    13441 ttttgtatga tttaaatatt gcgcttattg tatggtccct ccgtaattat ataagattta
    13501 tcattttttt catttcttgt tgtttgtata ttgataaata cagtataaat ctaggtgaat
    13561 acttaataaa gctattctat tggtttaata tattttttac ctcgttccaa tattttgtgc
    13621 ttttaaaatc aggagatttt cttggaggaa tttttggaaa cgaattggga atttctaata
    13681 cctacttgca tattctttta attctcatct tgatattatc tgttgttaat tatgtatcag
    13741 ataattcgag tttagttatt ttaacaagtt atatcgtttc aactctatac gtagctgctt
    13801 tgtcagagtt aaagattatt tttgtggaat tacctattat tattattttg actttactat
    13861 ttaaaagatt aggaataaaa atactgctta aaataatatc tatcacttgc atagtggtgg
    13921 tcgctttggc aatctcaatt cctattttat atgaattatt ccctatattt gacaattttt
    13981 ttaaattaga aaaattattt ggctattcaa caggaaacta ttcaactagt tctgattttg
    14041 gtcggttaag ttcaattgtt caaataatct caactatttt ttatggagat gtttggcaga
    14101 ctttatttgg tattggttta ggagaggcgg aaatttcaaa aattccgata tttagtggtt
    14161 ccttttatta taattacgaa tacacccatt actatctgtt cactttatca tatgttttta
    14221 ttgagaatgg atttatagga ttgttcctat tcatgtttat gccaatttac cttgctttaa
    14281 agatgatttt tgagcgaggg acatctaaat atgatcttct tctgatagta ttatctattt
    14341 ctttatttat gctcttgttg tataataata caatgaggtc agagatatat tatctttatt
    14401 tatttgttct ttcatgggga gttgcaatca atagaggaaa tgggggatgt tatgaaaaca
    14461 ataaaaaatt atgcttataa atctttttat caactatttt tgataatagt accttttata
    14521 acaatcccat atgtttctag aattttagga gcagagttaa tagggataaa ttcttataca
    14581 aacactataa taagttattt tgtgttaata gcaaatcttg ggattttgat atatggtaat
    14641 agaaccatag catatcatag agaaagtatt gaggagcgta gtaaaaaatt ttgggaaatt
    14701 gtctcaatta agttgctggt agcaattgtt gcctatgtca tatttattat atttttattc
    14761 ttttattcaa aatatagttg ggtttttgtg attcaatctg tacaaattat agctacggca
    14821 tttgatatat cttggctttt tgatggtgta gaagatttta aacgtacagt agtgagaaat
    14881 tttctggtta aaataatttc cattattcta atttttactt ttgtcaagtc tacagaggac
    14941 tttgacaaat acatatggat aacagtaggc tctactttaa tgggtaattt gacattatgg
    15001 agttatttac accattatat tattaaaatt ccgataaaaa gccttaagtt gagtgaacac
    15061 ttagttccca ttttgacttt attcatacca caaattgctt ctattgtatt tatgtcaatc
    15121 aataaaattt tactaggtaa tatttcgacg atatcgcaag caggctactt tgagaatgcg
    15181 gataaggtga ttagaattct tctggcttta gtatcatcta ttggagtagt tgtttttcct
    15241 aaagttgctc atgcgtatag gagtggtgat atgaagagag tattagggtt gacttatatg
    15301 acttttgatg cagttaatat tataactatt ccaattgtag ttggaatagt ttctattagc
    15361 cctacattct cttctatttt ttttgggacg gaattccaag gaatagataa ggttctgtct
    15421 gttctagtat tggagttaat tttcatggga tatacttcgg ttttaggtag tcaatatctc
    15481 attgtaacag ggcaaactta ctttttaagt atctcggtgt tcctaggaat attttctaca
    15541 gtgatatctt ctttcttttt cattccgata tacggagcgc ttggaagtgc gatttcatct
    15601 gtaattggag aagcatctat tatgattggt gaaatttact tgttaaggaa tcaagttgat
    15661 ttctattatc tatataggga tgtaccgaaa tacatgattg ctagcgctgt tatgtatatt
    15721 agtatctcgt cattgaatta ttttatttct tcgccatttg tatctttgct atcaagtatt
    15781 gctatgggtg cagtgactta tgttactgtt gtcttattac tatgcccaag aatagtaata
    15841 aaattattaa ataaaaacac aagatttttt tgaaatgata tataaaatcg taacaaaaat
    15901 ccaattacaa ttcatgactt tttactaatt ataaatttgc gattcatcta attaaaattg
    15961 aattatagat aatgaaaatt tagaaaggtg gccccattat gaaaggtatt attcttgcag
    16021 gtggttcggg aacgcgcctg tacccactta ctcgagctgc gtcaaaacag ctgatgccgg
    16081 tttatgacaa acccatgatt tattatcctt tgtcaaccct aatgttggct ggaatcaagg
    16141 atattttgat tatctcaaca ccacaggatt tgccccgttt taaggacctg ctcttggatg
    16201 gttccgaatt tgggattaag ctttcctatg cggaacaacc tagtcccgat ggacttgctc
    16261 aggcttttct tatcggtgaa gaatttatcg gtgacgatag cgttgcgctg atcttaggtg
    16321 acaatatcta tcacggttct ggtttgagca aaatgcttca aaaagcagcc aagaaagaga
    16381 aaggtgcgac tgtctttggc taccatgtca aggatccaga acgctttggt gttgtagaat
    16441 ttgatgaaaa tatgaatgct atctccatcg aagaaaaacc agaacagccg cgctctaact
    16501 atgcagtgac aggactgtat ttctatgata acgatgttgt cgaaattgcc aagagtatca
    16561 aaccaagtcc tcgcggagaa ttagaaatca cagatgtcaa caaggcttac ttggatcgtg
    16621 gagatttatc agttgagctt atgggacgtg gctttgcttg gctggatact ggaactcatg
    16681 aaagtttact agaggcttca cagtacatcg aaacagtgca acggatgcaa aatgttcagg
    16741 tagcaaactt agaagaaatt gcctatcgca tgggttatat cagtcgtgaa gatgtattga
    16801 ccttagccca accacttaag aaaaatgaat acggacagta tctgctccgt ttgattggag
    16861 aagcatagat gacagataat tttttcggta agacgcttgc ggcacgcaag gttgaagcta
    16921 ttccaggcat gttggagttt gatatccccg ttcatggaga taatcgtggc tggtttaaag
    16981 aaaatttcca aaaggaaaaa atgcttccac ttggatttcc agagtctttc tttgcagaag
    17041 gaaaattgca aaacaatgta tccttctcac gtaaaaatgt ccttcgaggc ctccacgcag
    17101 agccttggga taagtacatc tctgtagcag atggagggaa agttctgggt tcttgggttg
    17161 atctacgcga gggtgaaacc tttgggaata cctatcagac agtaattgat gcaagcaagg
    17221 gaatctttgt tcctcgaggc gtagctaatg gcttccaagt tctatcagat acagtgtcat
    17281 atagctatct ggtcaatgat tactgggctc tcgagctcaa acccaagtat gcctttgtga
    17341 actacgctga tccaagcctt ggtattgaat gggaaaatat tgcagaagca gaggtttcag
    17401 aagcagataa acatcatccc ctacttaagg atgtaaaacc tttgaaaaaa gaagatttgt
    17461 aaaaaggaaa gaatatgact gaatacaaaa atattatcgt gacaggtgga gctggcttta
    17521 tcggttctaa ctttgtccat tatgtttacg agaactttcc aggtgttcac gtgacagtcc
    17581 tagataagtt gacttatgct ggaaatcgcg cgaatattga ggaaatttta ggtaatcgtg
    17641 ttgagttagt tgttggtgac attgctgatg cggagttggt agacaagttg gctgctcaag
    17701 cagatgctat cgttcattat gcagcggaaa gccacaatga taattcgctc aatgatccat
    17761 cgccatttat tcatactaac ttcatcggaa cctatactct tttagaagct gctcgtaagt
    17821 atgatattcg cttccaccat gtatcgacag atgaagttta tggggatctc cctttacgcg
    17881 aagatttgcc aggtcatggt gaaggaccag gtgagaaatt tactgctgaa accaagtaca
    17941 atccaagctc gccttactca tcaaccaagg cagcctcaga tttgattgtc aaagcctggg
    18001 tccgttcttt tggagtcaag gcaacgattt ccaactgttc aaataactac ggtccttatc
    18061 aacatatcga aaaattcatc ccacgtcaga ttactaacat cctaagtgga attaagccaa
    18121 aactttacgg tgaaggtaag aacgttcgtg actggattca taccaatgac cattcttcag
    18181 gagtttggac aatcttgaca aaagggcaaa ttggtgaaac ctacttgatt ggggctgatg
    18241 gtgagaagaa caataaggaa gttttggaac ttatccttaa ggaaatggga caagctgcgg
    18301 atgcctatga tcatgtgact gaccgtgcag gacatgacct tcgctatgcg attgatgcta
    18361 gcaagctccg tgatgagttg gggtggaaac ctgaatttac caactttgaa gctgggctca
    18421 aggcaacaat caagtggtat acagataacc aagaatggtg gaaagcagaa aaagaagctg
    18481 ttgaagccaa ttatgctaag actcaggaga ttattacagt ataaaaagca ggaaatagct
    18541 gctttttatt gctatattgg gaagagttac atattagaaa ggtctagaga tgattttaat
    18601 tacaggggca aatggccaat taggaacgga acttcgctat ttattggatg aacgtaatga
    18661 agaatacgtg gcagtagatg tggctgagat ggacattacc gatgcagaaa tggttgagaa
    18721 agtttttgaa gaggtgaaac cgactttagt ctaccactgt gcagcctaca ccgctgttga
    18781 tgcagcagag gatgaaggaa aagagttgga cttcgccatc aatgtgacgg ggacaaaaaa
    18841 tgtcgcaaaa gcatctgaaa agcatggtgc aactctagtt tatatttcta cggactatgt
    18901 ctttgacggt aagaaaccag ttggacaaga gtgggaagtt gatgaccgac cagatccaca
    18961 gacagaatat ggccgtacta agcgtatggg ggaagagtta gttgagaagc atgtgtctaa
    19021 tttctatatt atccgtactg cctgggtatt tggaaattat ggcaaaaact tcgtttttac
    19081 catgcaaaat cttgcgaaaa ctcataagac tttaacagtt gtaaatgacc agtacggtcg
    19141 tccgacttgg actcgtacct tggctgagtt catgacctac ctagctgaaa atcgtaagga
    19201 atttggttat tatcatttgt caaatgatgc gacagaagac acaacatggt atgattttgc
    19261 agttgaaatt ttgaaagata cagatgtcga agtcaatcca gtagattcca gtcaatttcc
    19321 agccaaagct aaacgtccgc taaactcaac gatgagcctg gccaaagcca aagctactgg
    19381 atttgttatt ccaacttggc aagatgcatt gcaagaattt tacaaacaag aagtgagata
    19441 agtagtagaa tgattttcta gtctaataaa agaggcagat aatgaactcc aaaggagctt
    19501 aagatgtacg attatcttgt tgttggtgct ggtctctttg gcgcagtctt tgcccatgaa
    19561 gtagccttaa aaggaaaaaa gtaaaagtca ttgaaaaacg gaatcatatc gtgggtaata
    19621 tctatactcg tgaagaggaa ggaattcaag ttcatcaata tggtgctcat atcttccata
    19681 cttctgataa ggagatctgg gattatgtaa atcagtttgc agggtttaac cgttacacca
    19741 attctcctgt tgcaaactat aagggtgaga tttataacct tccttttaat atgaatactt
    19801 tcaataaact ctggggagtt gtaacgccag cagaagcaca agctaagatt gaggaacaac
    19861 gtgctatttt aaatggtaaa actcctgaaa atttggaaga acaggcgatt tctcttgtag
    19921 gtacagacat ctacgaaaaa ttaatcaaag actatacaga gaaacagtgg ggcaaaccaa
    19981 ctactgaact tccatccttt attattcgcc gtttaccagt acacctgacc tatgataaca
    20041 actattttaa cgatacctat caagggattc caattggtgg atacactcaa atagttgaaa
    20101 aatgtggatc atgaaaatat tgatgtagaa acaaatgttg atttctttgt gaacaaagag
    20161 caatatctga aagattttcc taagattgtc tttactggta tgattgatga attctttgac
    20221 tataagttgg gcgaactaga gtaccgtagt cttcgttttg aaaatgagac cttggatatg
    20281 gaaaattacc aaggaaatgc agttgtgaac tatacggatg cagaaacccc atatactcgc
    20341 attattgaac acaaacattt tgagtttggg agtcaagcaa agactatcat taccaaagaa
    20401 cattctaaaa catgggaaaa aggtgatgag ccttattatc cagttaataa tgatcgtaat
    20461 aatcatttgt ataaatcata taaaaaactt gctgatgagc aagggaatgt tatctttggt
    20521 ggccgcttag gacactatcg ttattacgat atgcaccaag taattggagc agctttgcag
    20581 tgcgtgagaa atgagttaga ttcatactca atgaaaatca aagagcaaac taggaagcta
    20641 gccacaggtt gctcaaaaca ctgttttgag gttgcagatg aaagctgacg cggtttgaag
    20701 agattttcga agagtataaa caagtaaaac tgactaccag ttattattta gaaatagtat
    20761 taaaaattc
//
LOCUS       DAVDFK010000036        18547 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.36, whole genome shotgun sequence.
ACCESSION   DAVDFK010000036 DAVDFK010000000
VERSION     DAVDFK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.36"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..379
                     /locus_tag="VUR04_001600"
     CDS             <1..379
                     /locus_tag="VUR04_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET5341472.1"
                     /translation="RNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKESK"
     gene            801..1181
                     /locus_tag="VUR04_001601"
     CDS             801..1181
                     /locus_tag="VUR04_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HET5341473.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            1640..2353
                     /locus_tag="VUR04_001602"
     CDS             1640..2353
                     /locus_tag="VUR04_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET5341474.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIGRDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2411..3013
                     /locus_tag="VUR04_001603"
     CDS             2411..3013
                     /locus_tag="VUR04_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341475.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFLNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3149..3802
                     /locus_tag="VUR04_001604"
     CDS             3149..3802
                     /locus_tag="VUR04_001604"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET5341476.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3812..4276
                     /locus_tag="VUR04_001605"
     CDS             3812..4276
                     /locus_tag="VUR04_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5341477.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4289..5557
                     /locus_tag="VUR04_001606"
     CDS             4289..5557
                     /locus_tag="VUR04_001606"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET5341478.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATRAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5571..5831
                     /locus_tag="VUR04_001607"
     CDS             5571..5831
                     /locus_tag="VUR04_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341479.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5842..7203
                     /gene="pdrM"
                     /locus_tag="VUR04_001608"
     CDS             5842..7203
                     /gene="pdrM"
                     /locus_tag="VUR04_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET5341480.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7357..8325
                     /locus_tag="VUR04_001609"
     CDS             7357..8325
                     /locus_tag="VUR04_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET5341481.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8341..9333
                     /locus_tag="VUR04_001610"
     CDS             8341..9333
                     /locus_tag="VUR04_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET5341482.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9551..10594
                     /locus_tag="VUR04_001611"
     CDS             9551..10594
                     /locus_tag="VUR04_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET5341483.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10658..12343
                     /gene="lpdA"
                     /locus_tag="VUR04_001612"
     CDS             10658..12343
                     /gene="lpdA"
                     /locus_tag="VUR04_001612"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET5341484.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12407..13396
                     /locus_tag="VUR04_001613"
     CDS             12407..13396
                     /locus_tag="VUR04_001613"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET5341485.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13469..14539)
                     /gene="xerS"
                     /locus_tag="VUR04_001614"
     CDS             complement(13469..14539)
                     /gene="xerS"
                     /locus_tag="VUR04_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET5341486.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(15123..16673)
                     /locus_tag="VUR04_001615"
     CDS             complement(15123..16673)
                     /locus_tag="VUR04_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET5341487.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16689..17468)
                     /locus_tag="VUR04_001616"
     CDS             complement(16689..17468)
                     /locus_tag="VUR04_001616"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET5341488.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17455..18306)
                     /gene="ylqF"
                     /locus_tag="VUR04_001617"
     CDS             complement(17455..18306)
                     /gene="ylqF"
                     /locus_tag="VUR04_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET5341489.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
BASE COUNT         5642 a         3445 c         3935 g         5525 t
ORIGIN      
        1 aagaaacaaa aatggtcaag ctgataccaa tcaaacggaa aaaccaagcg aggagaaacc
       61 tcagacagaa aaacctgagg aagaaacccc tcgagaagag aaaccgcaaa gcgagaaacc
      121 agagtctcca aaaccaacag aggaaccaga agaatcacca gaggaatcag aagaacctca
      181 ggtcgagact gaaaaggttg aagaaaaact gagagaggct gaagatttac ttggaaaaat
      241 ccaggatcca attatcaagt ccaatgccaa agagactctc acaggattaa aaaataattt
      301 actatttggc acccaggaca acaatactat tatggcagaa gctgaaaaac tattggcttt
      361 attaaaggag agtaagtaaa ggtagcagca ttttctaact cctaaaaaca ggataggaga
      421 acgggaaaac gaaaaatgag agcagaatgt gagttctagt tctcattttt ttcatgaaaa
      481 tgtgcaaaat atagtagatt gaaactagaa tagtatacct ctacttctaa aacattgtta
      541 gaaatcgatt tgactgtcct gttcttattt cattttacta tatcttaaca gatagtgtaa
      601 ataaagataa actatttact ggctaattaa tcagttaaac actagttaag gagtaatgat
      661 gaaaaaaaga acaatactat tattgatggc cagtctgtta gctcttgtct taggagcatg
      721 tggtttcttg gacatattga tcctggatca ttctcatcag gattactctt tactgctatt
      781 ttagaaactg gagtggtttg atggaaagta ttggtattgg tcttgttatc gtttcacatt
      841 ccaaacacat tgcagaaggt gttgttgaac tgattagtaa agtagctaaa gatgttccaa
      901 ttacttatgt aggaggaacc gagggcggag gaattggaac gagttttgat caagtagata
      961 gggttgtttc cgaaaatcca gcagatactt tacttgcctt ttttgaccta ggttctgcta
     1021 aaatgaactt aaaaatggtg actgatttca gtgataaaag tatcatcatc aacagggttc
     1081 caattgtaga aggtgcctat aatgcagctg ctcttcttca ggctggtgca gaactgtcag
     1141 ttattcaaat acagttagcg gagcttgaaa tcaataaata aggaatttta ctataactct
     1201 ttttatagat aagctattga ttatctcaac tataaaatgt taagtaaatg atttcaaaat
     1261 cagaaaggga ttgctttatg cagttccttt ttattttaac aggagtgaaa ctatagtgtt
     1321 tctaaattgt gaatcaatca aaactgattg tgatggggct attctagctt tagaaacctt
     1381 caaaaattaa aatttaaggc aatcaattac ttggaagagt atgaaagcat ttagtttata
     1441 ggaattctag gcctagaatt acatatgtat ttatgaagac ggggtgttcg atagttagta
     1501 ttgttctatt ctgaaagatt tgagctgtca gttgtataga aagtgttcga atttttttta
     1561 agtgattaaa ttagttaatt gtatgaggtg ctttatgata taatgttctt aatgaatttt
     1621 cagaaaggaa aacctcaaat tgttctacaa atttctactc ttcgacctcg accacactct
     1681 tcttgatttt gatgctgctg aggatgtggc tttgacccaa cttctaaaag aagaaggagt
     1741 tgcggatatt caggcttata aagattatta cgttcctatg aacaaggctc tctggaaaga
     1801 cttggagctg aagaaaatca gtaaacaaga gctggttaac acgcgctttt ctcgtttatt
     1861 tgctcatttt ggacaagaaa aagacggtag ttttcttgcc cagcgttacc aattttacct
     1921 cgcccagcag ggacaaacac tatcgggcgc tcatgatctc ttggacagcc tcattgggcg
     1981 tgattataac ttgtatgctg cgacaaatgg cattactgcc attcagacag gacgtttggc
     2041 tcaatctggt ctagcacctt atttcaatca agtctttatc tcagaacagt tgcaaactca
     2101 aaagccggat gctctttttt atgaaaagat tggccagcaa attgctggat ttagtaaaga
     2161 aaagacgctg atgattggag attctctaac cgccgacatt caaggtggca ataatgcggg
     2221 gattgacact atctggtata atcctcatca cctcgaaaat cacacacaag cccagccgac
     2281 ttacgaagtc tattcttacc aagacttgct ggattgttta gataaaaata ttcttgaaaa
     2341 gatcacattt taaaggagac gagctaatga ctacaaaaaa gctaatatta ctattgaaga
     2401 gtacattgaa atgtctgaag ttgattttaa tgaagctgtt aattatgaat ttacatctga
     2461 cacttgtcaa ttagcaaata gtatttatca atctcttttt aagttttttg ataagaaaaa
     2521 tttctctggc gatttaattt ttacttggaa atctccatca ttagtcaaag aaggggatta
     2581 tattgggaga agggattcac aagtagataa tcttagagta ataggaaata tatttctgaa
     2641 ttatcttact aatcgaaaat atagcctcaa tatgaatcgt aatggctgta tgggagattt
     2701 tcctcatgac ttttttgata tatacctaga tcatgtagca aaatatgcct acgaacaaaa
     2761 agttaataat attaaagagt attatccttt aaaaagagcg attttacacc aagagaatgc
     2821 attgtatttt cgattttttt ctaattttga cgacttttta gaaaaaaatt atttaaagac
     2881 tatatggcaa gtttctaaag aaactccttt ttctgaaatg gattttaata tgtttaaaaa
     2941 tatttcagaa aagataatct tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa
     3001 ttataaaaaa tagtcagtct ttataaactg tattcacgta ttcaaatcgt atatagtcga
     3061 tttattaaat ctttagataa attgtaaaaa gtggtttcca tagccacttt ttgctataat
     3121 agaggcagta aaaatgaagg agtcagctat ggaacactcg tcttggcatg ctttgattaa
     3181 ggcgcaatta cctgagggtt atttcgggaa aatcaatcag tttatggagc aggtctattc
     3241 tcaggggatt atttatccac ccaaggaaaa ggtttttcag gctctcttga caacactgct
     3301 tgaagaagtt aaggtggtaa ttctagggca agacccctat cacggaccag gtcaagcgca
     3361 gggcttgagt ttttctgtac ctgactctat cccagctcca ccatccttgc aaaatatctt
     3421 gaaagaattg tcagatgata tcggagttaa gaaatctcat gatttgacag cttgggctga
     3481 gcaaggagtc ttgcttctta atgcttgttt gactgttcct gctggacagg ccaatggtca
     3541 tgctggtcaa atctgggagc cttttactga tgctgtgatt caggtggtca atcatctaga
     3601 tagaccagtc gtttttgtac tctggggagc ttatgcacgt aagaagaagg ccttagttac
     3661 caatcctcat cacttgatta tcgaatcagc ccatccaagt cctttgtcgg tttatagagg
     3721 attttggggt tccaagccct tttccaaggc caatgcattc ttaaaagaga caggacaaga
     3781 gccaatcgat tggcttagat aaggagaaaa tatgcctcag ttagcgacga tttgctacat
     3841 tgataatggg aaagaactgc tcatgctcca tcgtaataag aaacccaatg atgtccatga
     3901 agggaaatgg attggtgtgg gtggtaagct agagagagga gagacgcccc aggaatgcgc
     3961 ggcgcgtgaa atccttgaag aaacagggct caaagccaag ccagttctaa aaggtgtcat
     4021 cacttttcct gaatttacac cagatttaga ctggtacacc tatgttttta aggtgacgga
     4081 gtttgagggc gacttgattg actgcaatga ggggacgcta gaatgggttc cctatgacga
     4141 ggttttgagc aagccgactt gggaaggtga ccacaccttt gttgaatggc ttttagagga
     4201 taaacccttc ttttcagcca agtttgttta tgatggggat aaattgttgg atacccaagt
     4261 tgatttctat gaataaagga gaaagcagat gctactaatc aaaaatggtc gtgtaatgga
     4321 tcccaagtct ggtttggatc aagtttgtga tgtcttagtt caagatggga aaattatcaa
     4381 aattgcgcct gagatcacgg aagaaggagc agaaacgatt gatgctactg gtcttgtggt
     4441 tgctcctggt ttggtcgata ttcatgtgca tttccgtgaa cctggtcaaa cacataaaga
     4501 agacattcat actggtgccc tggcagccgc tgcaggtggt tttactactg tcgtcatgat
     4561 ggctaatacc agtccaacca tttcagacgt ggagactttg caagcagttc tccagtcagc
     4621 tgccaaagag aagattaatg tcaagacagt tgcgaccatt actaaaaact ttaatggtaa
     4681 aaacttgact gactttaagg cgctcttaga agctggtgcg gttggtttct ctgatgacgg
     4741 tattccgctt gagagcagta agattgtcaa ggaagccatg gaggaagcca aaaaactcaa
     4801 tacctttatc agccttcatg aggaagatcc aggtttgaac ggtgttcttg gctttaatga
     4861 aaatattgct agagaacatt tccatatctg cggtgctact ggggtggctg agtacgctat
     4921 gatggcgcgt gatgtcatga ttgcctatgc aactagagcc catgttcaca tccagcattt
     4981 gtctaaggaa gaaagtgtta aagtagtgga gtttgctcag gggttaggtg cagaagtcac
     5041 agcagaagta gcaccacagc atttctctaa gacagaagca cttcttttaa cacaaggtag
     5101 caatgctaag atgaatccac cgcttcgttt ggaatcagac cgtcgtgccg ttatcgaagg
     5161 tctcaaatca ggtgtcatca cagttattgc gactgaccac gcgcctcatc atgtagatga
     5221 aaaaaatgtt gaagatatta ccaaagcgcc atctggtatg actggcttag aaacatccct
     5281 gtctctcggc ttgacctatt tagtagaagc tggtgagttg agcttgatgg aattacttga
     5341 aaaaatgaca tacaacccag ccaagcttta caactttgaa gcaggttact tggctgagaa
     5401 tggtccagca gatatcacta tttttgatgc caaggctgac cgccttgtgg actcccattt
     5461 tgcttccaaa gcagctaatt caccattcat cggtgaaacc ttaaaagggc aggttaaata
     5521 taccatctgt aagggacaaa tcgtctatca agcttgatag gagttagaat atgaattatt
     5581 ttcgaaaacg tagggagaga caagcgaaat ctaatagtgg aatttactgt cccgcagcta
     5641 atcgttccaa aattcaatat gaaactaaag aaaaagctga ccatgcggtt caatatgata
     5701 acggaggttt agttagaagc tattattgtc gtacatgtgc gtgttggcat actacttcaa
     5761 aatctaataa acctccgcta agtttgaaaa actatggtct gaaactcttt ggtttagata
     5821 aatcagaata gaaagagaag tatgtataag acaaagtgtt tacgagagaa gttagtatta
     5881 tttttaaaaa ttttcttccc aatcctgatc taccaatttg ccaattattc tgcctctttt
     5941 gttgatactg caatgacagg tcaatacaac actatggact tggctggtgt atctatggca
     6001 accagtatct ggaatccttt ctttacattt ctaacaggga ttgtgtcagc cttggtgcct
     6061 atcattggtc accatcttgg tcgaggcaaa aaggaagaag ttgcgtctga tttttaccaa
     6121 tttatttatt tggccttggg cctatctgtg gtcttgctgg ggatggtact tttcttggca
     6181 ccaacaatct tgaatcatat tgggttagaa gcagcagtag cggcagtagc ggttcgctat
     6241 ctttggtttt tatctatcgg gattatcccc ttgttgctct ttagcgtcat tcgttccttg
     6301 ctggattcgc tgggcttgac caaactgtcc atgtacctca tgcttttgtt actccctctc
     6361 aatagcggat ttaactatct cttgatttac ggtgcctttg gtgttccaga actgggaggg
     6421 gctggtgctg gtttaggaac atccttggcc tactgggtct tgcttgggat ttctgttctg
     6481 gttttattta aacaggagaa gctcaaagcc ttacaccttg agaaacgaat tccacttaat
     6541 atggataaaa ttaaggaagg agttcgttta ggtctgccta ttgggggaac tgtcttcgcg
     6601 gaagtggctg tcttttcagt ggttggcttg attatggcta agttttcgtc cttgattata
     6661 gctagtcacc agtcagctat gaacttttca agtcttatgt acgcctttcc tatgagtatc
     6721 tcatcggcta tggctattgt cgtttcctat gaagtgggag ccaagcgatt tgatgatgcg
     6781 aaaacctata ttggtctagg aagatggact gccctcattt ttgcggcctt caccttaacc
     6841 ttcctttaca tttttagggg aaatgtggcc agtctttatg gtaacgaccc aaaatttatc
     6901 gatttgacag cgcgtttttt aacttatagt cttttcttcc agttagcaga tacctttgcg
     6961 gcgccgcttc agggaatttt gcgggggtat aaggatacag ttattccttt ttaccttggt
     7021 ttgcttggtt attggggcgt agcaatccct gtggctacgc tatttgattc cctaacagat
     7081 tttggagctt attcttactg gatcggcttg attattagtt tgattgtgag tggggcgctc
     7141 taccgttggc gtttaactgt gattatgaag agatttgaat ctttagcaaa atccaaacgc
     7201 taaaaagttt gtgaaaaaat attcttgaca agaaaatccc ttgttttcac ggggttttct
     7261 tttttatttt gtgaaatttc ttttagaaaa actttgacag tatttgccaa aagcggtaaa
     7321 atagtaaggt aagaagaaag ttagaaaggc aagaagatgt caactttaga taaaaatctt
     7381 ttgctagaaa tgttccgtaa gatggaagaa atccgtcgca tggacttaaa aattgcacaa
     7441 ttagtaaaga aagggaaagt gccaggaatg acgcactttt ctgttggtga agaggcagct
     7501 aacgtggggg ctatgttagc tctcaatcca gatgatctga ttacctcaaa ccaccgtgga
     7561 cacgggcaag ctattgctaa agggattgac ctcaacggaa tgatggctga aatccttggt
     7621 aaatacactg gaacctgtaa agggaaaggt ggatctatgc atatcgctga ccttgatgct
     7681 gggaaccttg gtgccaatgg tatcgtaggt ggtggtatgg ggatcgctgt cggtgcagcc
     7741 ctcagtcagc aaatgcaaaa taccggtaaa atcgttgtct gcttctttgg agatggtgcg
     7801 accaatgaag gtgttttcca cgaagcagtg aacatggctt ctatctggaa cctgccagtc
     7861 attttctatt gcattaacaa cggttacggt atctctgcgg atatcaagaa aatgaccaat
     7921 atagaacata tccatcaacg tagcgccgct tatggaattc ctggaatgtt catcgaagat
     7981 ggtaacaatg tcatcgatgt ctatgaagga tttcagaaag ctgtggacca tgttcgcagt
     8041 ggcaatggtt cagtcttgat tgaaagtgta acttatcgct ggctcggtca ctcatcatct
     8101 gaccctggta aatatcgtac gcgtgaagaa gtggaattgt ggaaacaaaa agatccaatc
     8161 gaaaacctcc gcaattacct tattgaaaat aacattgcaa gtgccgaaga attggaagaa
     8221 atccaagcgc aagtaaagga agcagtagaa gcttctgtta aatttgcaga ggaaagccca
     8281 ttcccaccgc ttgaatcagc ctttgaagat atttacgcag actaaggaga aagagataaa
     8341 atggaaacaa aaacaatgtc cttccgtgac accattatcc ttgctatgtc tgaggaaatg
     8401 cgtcgcgatg aaaatgtgtt cttgatggga gaagatgtcg gtgtcttcgg aggagacttc
     8461 ggtacttctg ttggaatgct tgaagaattt ggtccagaac gtgtccgtga ctgtccgatt
     8521 tctgaagctg ccatctctgg agcagcagca ggagcagcca tgacaggact tcgtccaatc
     8581 gtcgatatga ccttcatgga cttctctgtt attgccatgg acaatatcgt caaccaagct
     8641 gctaaaacac gttacatgtt tggtggtaaa ggtcaggttc caatgactgt tcgttgtgca
     8701 gctggtaacg gagttggctc tgccgcccag cactcacaat ctctagagtc ttggtttact
     8761 cacattccag gacttaaggt tgtggcacct ggaacacctg cggacatgaa aggcctgctt
     8821 aagtcttcta tccgtgataa caacccagtt attatacttg agtacaagtc agaatttaac
     8881 caaaaagggg aagtgccagt tgatccagac tacacaattc cacttggggt tggtgaaatc
     8941 aaacgccaag gaacggatgt aacagttgtt acttatggaa aaatgcttcg ccgtgtggtt
     9001 caagctgctg aagaattagc agaagaagga atttcagttg aaattgttga cccacgtacc
     9061 cttgttccgc ttgataagga tatcatcata aactcagtga agaagactgg taaggttgtt
     9121 ctggtcaacg atgcccacaa aacaagtggc tatatcggtg aaatttcagc tattatttca
     9181 gaatcagaag catttgacta tctagatgca ccaatccgcc gttgtgcagg agaagatgtg
     9241 ccgatgcctt atgcacaaaa cctagaaaat gcaatgattc caacagttga aagtatcaaa
     9301 gatgcaatcc gaaaaactta taacaaagaa tagagttaca taagataagt tatgtaaata
     9361 aaataaagct gacgagaaac tttgtatctt ttaggtgcag agctcttcgt cattaatatc
     9421 ttatattcga gcacgggcta aaagctcgga aaaaagataa atctccttgg cttcatcgaa
     9481 gccatcgtcg atttcctatt tttcagtcgc ttttgacgcc ctttgtatca taaatagaat
     9541 tggagaggtc atggctgatg acaagctaag agcgactcct gcagctagaa agttagcgga
     9601 tgatttaggg ataaacctct acgacgtttc tggctcaggt gcaaacggtc gtgtccacaa
     9661 agaagacgtg gaaacttata aagacacaaa cgtggttcgc atttcgccac ttgcaaaacg
     9721 aattgccctc gaacataaca ttgcttggca ggaaatccaa ggaaccggtc atcgtggtaa
     9781 aatcatgaag aaggatgttt tggccctgct tcctgaaaat atcgaaaacg atagcatcaa
     9841 atctcctgct cagattgaaa aagtggaaga agtccctgat aacgtaacac catatggtga
     9901 aatcgagcgt attccaatga caccaatgcg taaggttatt gcccaacgca tggttgaatc
     9961 ttacttgact gcgccaacct tcaccctcaa ctatgaagtt gatatgactg aaatgttggc
    10021 tcttcgtaag aaggttcttg agccaatcat ggaagcaact gggaagaaga ctactgtaac
    10081 agaccttctt tcgcttgcag ttgttaagac tcttatgaaa cacccataca tcaacgcttc
    10141 attgacagaa gatggcaaga ctattatcac tcacaactat gtcaatcttg ccatggcagt
    10201 tgggatggat aatggattga tgacacctgt tgtttacaat gctgagaaga tgagtctttc
    10261 agaactggtg gtagccttta aggatgttat tggccgtacc ttggatggta aattggctcc
    10321 aagtgagtta caaaattcaa cattcacaat cagtaatttg ggaatgtttg gtgttcagtc
    10381 ctttggtccg attattaacc aacccaactc agctatcctt ggtgtcagtt cgacaatcga
    10441 gaagccagtt gtcgtcaatg gtgaaattgt gattcgccca atcatgagtt taggattaac
    10501 cattgaccac cgtgtcgtag atggtatggc tggtgctaag tttatgaagg acttgaaaga
    10561 gttgattgaa acgccaatct caatgttaat ttaagagcaa gagtattcat ttttaagata
    10621 tagataaagg aaggaagaca tggccttaga agtaattatg ccaaaagccg gcgtggatat
    10681 gacagaagga caaatcgtcc aatggaataa aaaagtcgga gaatttgtaa aagaaggaga
    10741 aatccttttg gaaatcatga ctgataaagt cagcatggaa ttggaagccg aagaagatgg
    10801 gtacttgatt gccattctca aaggagatgg tgaaactgtc cctgtaacgg aagttatcgg
    10861 ttaccttggt gaagaaaggg aaaacatccc aacagctgga gcagcatcgc cagaagctag
    10921 ccctgtacct gtagcaagta cctcaaacga tgatggtaag agcgatgatg cttttgatat
    10981 cgttgtgatt ggtggaggtc ctgctggtta tgttgcagcc attaaagctg cccaactcgg
    11041 cggtaaggtt gcccttgttg agaaatctga acttggtgga acctgcttaa accgtggatg
    11101 tattccaacc aagacctacc ttcatagcgc tgaaattatt gaaaatatcg gtcatgctgc
    11161 aaatcgtggt atcgtgattg aaaatcctaa cttcactgtt gatatggaaa aacttttaga
    11221 aactaaatct aaagttgtta atactcttgt tggtggtgtt gcaggacttc ttcgtagcta
    11281 cggagttgct gttcataaag gaattggtac aatcactaaa gacaagaacg tcttggtaaa
    11341 tggttctgaa ttgcttgaaa ccaagaaaat cattcttgct ggtggttcaa aagtcagcaa
    11401 gatcaacgtc cctggtatgg aatctccact tgtcatgact agtgatgaca ttcttgaaat
    11461 gaacgaagtg ccagaaagcc ttgttatcat cggtggtgga gttgtcggta tcgaactcgg
    11521 tcaggccttc atgacatttg gttcaaaagt gactgttatc gaaatgatgg accgtatagt
    11581 tccagctatg gatgtggaag tttctaagaa ccttcgcttg atccttgagc gtaaaggaat
    11641 gaccatcttg actggtacta aactgcaaga aatcattgag gaaaatggtc aacttcgtat
    11701 caaggttgaa ggaaaagacg atatcatcgc aagcaaagct cttctttcaa ttggtcgtat
    11761 gccagacctt gaaggtattg gagaggttga gtttgaattg gatcgtggtt gtatcaaggt
    11821 caacgaatac atggaaactt cagttccagg catttatgca ccaggtgaca tcaacggtac
    11881 taagatgttg gctcacgcag ctttccgcat gggtgaagtt tccgctgaaa atgcccttaa
    11941 aggaaatcat gcagttgcca aattgaattt gactcctgca gccatctaca ctcttcctga
    12001 agtagcagca gtaggtttga cagaagaaca agcccgtgag aaatacgatg ttgccatcgg
    12061 taagtttaac tttgctgcta acggtcgtgc tattgcatct gacgcagctc aaggtttcgt
    12121 aaaagttatc gctgataaga aatacggaga aatccttggt gtacacatta ttggtcctgc
    12181 agccgcagaa ttaataaacg aagcatcaag catcatcgaa atggaaatca ctgttgagga
    12241 aatgctgaag accatccacg ggcacccaac ttactctgaa gtgatgtacg aagcgtttgc
    12301 agatgttcta ggaatggcca tccattcacc taagaaaaaa taaaacgaag atagattaga
    12361 ctggaaggtt atttccagtt tctatcatat aaagtaaagg gatatcatga aatacattat
    12421 caatcattca aatgacactg cttttaatat tgccttggaa gaatacgcct ttaaacacct
    12481 tttggatgag gatcaaatct tcctactttg gattaacaag ccatctatca ttgttggtcg
    12541 tcaccagaac actatcgaag aaatcaaccg tgattatgtt cgcgaaaatg gtattgaggt
    12601 agttcgccgt attagtggtg gtggagctgt ttaccacgat ttaaataacc tcaactacac
    12661 gatcatctcc aaagaagatg aaaataaggc atttgacttc aagagcttct caactccggt
    12721 tatcaatacc ctggctcaac tcggggttaa agctgagttc acaggtcgta atgaccttga
    12781 gattgatggt aagaagttct gtggcaatgc ccaagcctat atcaacggcc gtatcatgca
    12841 ccacggttgc ttgctctttg acgttgattt gtcagtcctc gcaaatgccc ttaaggtttc
    12901 aaaagataaa tttgaatcaa aaggtgtgaa atccgtccgt gcccgtgtaa ccaatattat
    12961 caatgaatta ccaaaaaaaa tcacagtcga aaaattccgt gatttactct tggaatacat
    13021 gaaaaaagag tacccagaga tgactgaata cgtcttttca gaagaagaat tggccgaaat
    13081 aaatcgcatc aaggatacta agtttggaac ttgggactgg aactatggta aatcacctga
    13141 atttaacgtc cgtcgtggaa ccaaattcac tagtggtaag gttgaagtct ttgctaacgt
    13201 tactgaatca aaaatccaag acatcaagat ttatggtgac ttctttggta ttgaagacgt
    13261 tgctgcagta gaagctgtcc ttcgtggggt gaaatacgaa cgcgaagatg ttcttaaggc
    13321 gctaaaaacc attgatatca cacgctactt cgctggtatt agccgtgaag aaatcgctga
    13381 agcggtagtt ggataaatca aaaagaagtt ggccaactaa ccaacttctt tttttgatat
    13441 ttatttacat aatttaaaat acgtaaaatc ataaactatc cagagcattc ttttgttcat
    13501 cactaacaat atgggtatag aggtcagtga cttgtgtgct agcatgtcct agttggtgac
    13561 tgactaaaac ttgtgattta gtcgcatcat agagcctagt tgctagtgta tggcgcagtt
    13621 tatggggtgt tacacgcact ttaaaatcct ctgagtattt agcaaccatt ttctcaacgc
    13681 tagaagcatc gatacgatta ggaacacctc tgtagagagt taaaaaaagg gctgtatctg
    13741 ttttttccgt tttatagcgt tgattccgaa tggccagata attctctaaa taaggtttag
    13801 caaaagcagc gacattgact gagtcacgtt tgccaccttt tcgagtaaca tcaataacca
    13861 tcatttttag attgagatct cttagatcta gattaacagc ttcagataag cgaacaccag
    13921 atgccaagag aagggcaata atggctaaat ctcgttcttt atttttgttg aatgatgaga
    13981 gagctcgatt tgaaagctgt tgtgggtgct cttgatcgat ataagttaga aaaccttctg
    14041 tttcatcacc tagaaagagt ttttgcttga tattttcagc tctggcagca agggtttctt
    14101 tctttttctt ggttgaaact tttttcatta cattacgata gaaataaggt tccccctgat
    14161 cgttttcaac ctcctcggtt agatacttgt aaagactaga aagtgctgat aaggttcgat
    14221 tgatagttgt ctgtgaaaca ccttgttttg ttgtattagc attcagcaag ggacgttcac
    14281 gtagataaag gataaaggat tccatgtctt tcttagacat attttccaaa actgataaag
    14341 gaatatcgga tattttatca gcgtttgaaa taccagactc caaaacccag ctgaaaaatc
    14401 ggtcatattc cttaaggtat tcgtacaggg ttgtaaaact gtagggcaca gccagtttag
    14461 attggtagta ttccagaaca taccagggca tgagttgttt tagtttgtcg attcgttcca
    14521 gtaaaatctc acgtttcatg tattttctcc ataattaagt atactagtag tatagcatag
    14581 acttgtatat ttttcaagaa aattatagtt tttctgaaag atgttatagg agtttttcaa
    14641 agtgataaaa agacttagac ctacaaacaa aacagaataa ggaaaataat aaaaatctca
    14701 cccactaaac ttctgttaat actacataac tgaagagcta tataaggagc tatgagatac
    14761 aaaacacatt gtataataga ttgaaactag aatagtacat ctgaacttct aaaacattgc
    14821 tagaaattga tttgattgtc ctgattgttt tatcctattt ctatttcatt tcactatata
    14881 attgctattg ttttcttttt catgatttta atcttactgt acagatttga tacagtaaac
    14941 tcctttctag ctttatactt tatcatttct aacttaatta tagtcttatt tttaataaag
    15001 ttcaattatt tatatgtaaa aatcctcatc agtaaaaaat aaccgatctc atttctgaga
    15061 atcggttttc taaataaatc aaaccgatca tttacataac ataaattatg taaatgatca
    15121 tactacaaca acaaatcttt gacttttcca atttcacttt ttggaataac caggtgaatc
    15181 atatcaccca gatacattct ggttgagccg ttaactgttt ggctcttgcc attatggact
    15241 tgagttgtga tgaggacgtt gtgtggtaag ttgagttcat gaacttgttt cccagcaatt
    15301 ttatcagaaa ctggtatttc gataagtgta acttctcctt cgctagatac ttcttctgga
    15361 agcatttttt ccagcatggc ttcatagact ggcgtacctt tgagcaaatc catgataata
    15421 taagaaacaa gagtgacaag accaagtggc atgaggttgc gaatatctcc taccatctca
    15481 gttacgagga tcatagcggt taagggagct tttgatatgg ctccaaaata gccactcatt
    15541 cctagaatga caaatatagg gaattgctct tgactgacaa gtccaagatt gacacagata
    15601 acaccaacta aggcaccaag caaagaacca agagctaaaa tggggaggaa aattcctcct
    15661 ggcagtccac ttccatagct aatcatactc caaataaagc ggatcaaaaa gtaagctaat
    15721 aaaacttgga aactaaaatt ttgttcagtt aaagaaagga caagctgatt tccgccacca
    15781 aggatttgag gtaagaagat tccgactggt atgataagga taaaagccaa gatgggataa
    15841 taagctctat ccaaatggat tttttgacca atcaagtcat aaactcttcc aacgtttaat
    15901 acagctttct catagagaaa gcctgaaaat ccaaggaaaa ttcccatgac gagatatatc
    15961 caatactgat ctagggtcat gggaggaatg ttatctggca tatccaatac tggtgtcaaa
    16021 ccgaacatga gtagagacac aaagtttgct acgatgctgg ctgctagagt tgagacccag
    16081 aaaaagcgcg aaaaatggtg atagacttct tctacaacaa agagaagtgc tgcaatagga
    16141 gcattaaagg ctgcggctaa acctgctgca gctccactgg caatcaagga acgttcctct
    16201 actggactgg atttgagcca cttggcaatt cctttaccac caactgctcc aagttgaatg
    16261 ctgggtccct ctcgacccag catgagtcca ctggcaatag caagaatacc tagcacatat
    16321 tttttccaaa gaatgcccca ccagttgagg gacatgaggc ctttcagttc ggcttcgact
    16381 tgaggaattc ctgagccttt aatatctttt tctgaccgtg ttagtttggc actgagccaa
    16441 cagatgagta tataaaacaa aaccagtaca aaaagattgc gcactaagta cccttgatct
    16501 tgataaactc cttgtatcag gtggaagccc ttttcaatta agaaacgaaa ggatccgacg
    16561 ataattccaa cgatgaggcc gacaatgatt cctcgaccaa cttgggatag tatagtgctg
    16621 gatgcaaagg cgaattcttt cttagaacgg actatttccg actgttcctc catggtattt
    16681 cctttcaatt aactttcttt tttacctaaa accagtgatt taacgggttc aaagctggtt
    16741 cggtgaattg gggtaactcc tagttttgtg aggccttcca gatgtttagc tgtgccatat
    16801 cctgcattag tagcgaaatc atagccaggg aactgctgat cgtattcctt catcaattca
    16861 tcacgtgtta ccttggctac tatagatgct gctgcgatag agagggagtt ggcatctcct
    16921 ttgataatgg aggtttgtga aatgggcaag tccagtttca tggcatcaat caaaaggtgc
    16981 tctggttgag ggctgagctg ggagattgct tcttgcatgg ctagtttggt tgcttcatag
    17041 atgttgactt ggtcgatgac ctgattatct atgataccaa ttccaatcga caaggcttgg
    17101 tcttgaacgg cttggaaaat ctccagatgt ttctttttag gaattttctt gctgtcgttg
    17161 agacctttaa tcttacaatt tttaggtaaa ataacggccg cagcgactac aggaccagca
    17221 agaggaccac gaccaacctc atcaatacct gcaattaagg tcaatccttg cttataaagt
    17281 tctttttcat aagaaagcat ggattccaag cgcaaatttt catctaattc agcttggatg
    17341 gctcttttac gcttgctgat ttccttttga actcctgagc gattatcctt ttcaagctct
    17401 aaaaaaatag ggctttctaa ctccttgact gtcacaagga gttctttgat ttctttaatc
    17461 gttgccatcg aggtcttcca atgtatctaa ggtatagtta ccgagtttgc catcacggac
    17521 ttccttcacg aagagactgt aaaaacggtc atagtcatca cggaaaccga gggcgcgggt
    17581 catatccata ataatcacag acggttcttc ttcaattttc atttgtttga agcgttcagc
    17641 cagcttttct ggataatgtt ctttgaaata attgatacca aaaatggtaa cctcatccat
    17701 aggaagcaac tgatccttga tagctccagt caatgccaac ttaagtgcaa cagtttcatc
    17761 ctcaaactta ggccagagaa tccccggtgt atccaagatt tccagatctt tattggtttt
    17821 aagccattgt tgaccttttg tgacccctgg cttgtttcca acaacagcaa tctttttacc
    17881 agccaaacgg ttcatcagag ttgatttacc agcgtttgga atcccgataa tcatggtacg
    17941 caaggtttca atctgaatcc cacgttcttt ctggcgagca atcttatcag ccatgagctt
    18001 cttggccgca tctgttacaa cttttacagt cacttgctct ttggagttga tagctagcgt
    18061 ctggatttct tgtgattcaa aatactgacg ccattccttg gtcattgctg gatcagccaa
    18121 gtcggccttg tttaaaatca agagttttgg tttatcacca acaatcttgg tcaacatagg
    18181 attttgacta gatagaggca agcgtgcatc tactaaaatc gtcacaaaat caacaaattt
    18241 taaattttcc tgcacctgtc gacgcgcttt agacatgtga ccaggaaacc attgaatagt
    18301 agccattgag ttttttcctt tcgtagctct gaagctgtta atctagaact aagagatctc
    18361 aatctaaaaa tgaatgatgt ccaaacagtt cttgttttat gacataaaaa tctactttat
    18421 attatatcat gccttcttta ttttgtccga tgatagcctt ttaccctatc ttttacccta
    18481 tatagaaaaa agccatcaaa tgatgacttt tcagagggag caaaaactgt cctctttatg
    18541 ttttaaa
//
LOCUS       DAVDFK010000037        17641 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.37, whole genome shotgun sequence.
ACCESSION   DAVDFK010000037 DAVDFK010000000
VERSION     DAVDFK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.37"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            29..820
                     /locus_tag="VUR04_001618"
     CDS             29..820
                     /locus_tag="VUR04_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341490.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            813..1454
                     /locus_tag="VUR04_001619"
     CDS             813..1454
                     /locus_tag="VUR04_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341491.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWSLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            1458..2090
                     /locus_tag="VUR04_001620"
     CDS             1458..2090
                     /locus_tag="VUR04_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5341492.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRITKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            2118..2405
                     /locus_tag="VUR04_001621"
     CDS             2118..2405
                     /locus_tag="VUR04_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341493.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            2551..5064
                     /gene="secA"
                     /locus_tag="VUR04_001622"
     CDS             2551..5064
                     /gene="secA"
                     /locus_tag="VUR04_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET5341494.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            5145..6176
                     /locus_tag="VUR04_001623"
     CDS             5145..6176
                     /locus_tag="VUR04_001623"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET5341495.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYCVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLENGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            6178..7209
                     /locus_tag="VUR04_001624"
     CDS             6178..7209
                     /locus_tag="VUR04_001624"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET5341496.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            7248..7616
                     /locus_tag="VUR04_001625"
     CDS             7248..7616
                     /locus_tag="VUR04_001625"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET5341497.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            7606..8709
                     /locus_tag="VUR04_001626"
     CDS             7606..8709
                     /locus_tag="VUR04_001626"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET5341498.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            8728..10743
                     /gene="recG"
                     /locus_tag="VUR04_001627"
     CDS             8728..10743
                     /gene="recG"
                     /locus_tag="VUR04_001627"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET5341499.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVTFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDSEWRMIALHLEKKEHLD"
     gene            11059..12039
                     /locus_tag="VUR04_001628"
     CDS             11059..12039
                     /locus_tag="VUR04_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET5341500.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            12891..13118
                     /locus_tag="VUR04_001629"
     CDS             12891..13118
                     /locus_tag="VUR04_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341501.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            13406..16321
                     /gene="nanA"
                     /locus_tag="VUR04_001630"
     CDS             13406..16321
                     /gene="nanA"
                     /locus_tag="VUR04_001630"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET5341502.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKISRDYYARDLE
                     NVETVIEKEDVETNAANGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVS
                     SATKKDEYFTMAVYNNTATLEGRGSDGKQFYGNYNDAPLKVKPGQWNSVTFTVEKPTP
                     ELPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLT
                     VYNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRI
                     PALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKAS
                     DPSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQIL
                     YREGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTT
                     NKTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGP
                     HKGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTM
                     NNRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYV
                     QMSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNS
                     LQELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEM
                     GKGEMGKGVIGLEFDSEVLVNKDPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEI
                     IGIAKGSIESMHNLPVNLAGARVPGGVNGNKAAVHEVPEFTGGVNGTEPAVHEIAEYK
                     GSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            17337..>17641
                     /locus_tag="VUR04_001631"
     CDS             17337..>17641
                     /locus_tag="VUR04_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5341503.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKD"
BASE COUNT         5400 a         3170 c         3957 g         5114 t
ORIGIN      
        1 attactttct atttttagga ggtggcttat gaagattcct ctcttaactt tggcaaggca
       61 taaatttgtt tatgtcttgc ttactttgct ttttcttgct ttggtttatc gtgacgtttt
      121 gatgacttat ttcttttttg atattcatgc gcccgatcta gctaaattcg atggacaagc
      181 aattaaaaat gacttattaa aatcagcatt agattttcgt attctccagt tcaatctagg
      241 tttttatcaa tcatttatta ttccaatcat cattgttttg ctaggttttc aatatattga
      301 gctgaaaaat aaagttttac gattgagtat tggaagagaa gtgagctatc cagggttaaa
      361 aagaaagttg actttgcaag ttgcaagtat cccttgtttg atatatttag tgactgtgct
      421 gacaattgca attataacct atttccttgg gactttttct cctcttggat ggaattctct
      481 attttctgat ggaagtggtt tacaaagact cctagatgga gagataaaaa gctatttgtt
      541 ctttacttgt gtcctgctaa tcggtatttt catcaatgca atctattttt tacaaatagt
      601 tgattatgtg gggaatgtga ctcgttcggc aatcacctat ttgatgtttc tttggcttgg
      661 ttctatgctg ctctatagtg ccttgcctta ctatatggtt cctatgacga gtttgatgca
      721 agctagctat ggggatgtaa gtttgatgaa actctttact ccttatatcc tttatattgt
      781 cccttatatg gtgcttgaaa aatatgaaga taatgtttaa gaattttaac aatattttgc
      841 taaagagaaa gatcgtttta ctacttcgta tagttctgat gatgattttg ataaactatc
      901 tattgtcaac agcggttcaa aagcaggatg ctgttatctt tttcaagaga gaattgattt
      961 caatattttc ctataatgac tattctgaag cgaatttaga aatccccaaa ctcttgttaa
     1021 acctttcgct tttcatggta ggatggctct ctgtcatttt acttgaaagt gatttggcag
     1081 accattacca tcacttgatt cgctatcaat caagctcctt tttcgattat acaaggaaac
     1141 gattggttgt catttctaaa ttttttactc aagatttgtt tgtctggtct cttggtttac
     1201 ttcctctagg aattcatttc aaaacagtcg cacttttctt tttacttgct cagttaatga
     1261 tgttgtactt actactgtct tatctgatag cactgattag tgcgggcgct ggtttttcct
     1321 tttttctcta ttttttagca tttgtgggac aagaatggat gatggatcat attgtaacag
     1381 tgtatttagt actcttaagt ttattagtta tgttgattgt tagtcgcttg gaagagaaat
     1441 ttaagaaagg ataaacgatg agacttgaaa ttataaatgg acagaaaatt tatgggaaaa
     1501 gacctatttt aaatcagttg aatttggtgt ttcaatcagg aaaaatttat ggacttaaag
     1561 gtgataatgg atctggcaag acggttcttt taaagatact tgctggttat attaagcttg
     1621 acaaaggaaa agttcttcaa gatggtaaag tttacggggt aaaaaatcat tatattcagg
     1681 atgcaggaat tttaattgaa aaagtcgagt ttttatctca tttatccctg agagaaaatt
     1741 tggaactgtt aaggtatttt tcatctaaag ttacggaaaa aagaattgcc tattggattc
     1801 aatactatga tttacaggaa tttgaagaca ttgaataccg tcatttatcc ttaggaacaa
     1861 agcaaaaaat ggccttgatt caagccttta tttcctctcc ttctatactc tttctcgatg
     1921 aacctatgaa tgctttggat gagaagagtg tgaggataac caaacaggtc attttatctt
     1981 acctgaaaaa agaaaatggt ctggttatcc tgacgtcgca catatcggaa gatatttcag
     2041 acctttgtac agatgtatta gttgtcgaaa atggacatat acaaatgtaa aggatataca
     2101 atcctaggag atggcttatg gcacatctaa aatcatttat tacacgctat tccaaggttt
     2161 atattggttt agttctgctg atctggctgt ctttcttctt tatcccttgg gataaaccac
     2221 ttctggggat aaggattgac atcttcatca tacagaaaat cttgctagct tttggaattc
     2281 tgtccattct catggccttg ctgtccaaga aagtcagtct ctttgttttt ggactgattt
     2341 gctgtctttc tctttggatt aacttattta tcacatttgc cattttgccg atttttggca
     2401 attaaacagt cataaaagtc ggagaggtta gcttgaaaac taacctcttt ttccttttca
     2461 aaatggggat tcttccttga aaataatcag taattgtgct aaaattaaag gaacattcta
     2521 aaatattcgg aatttaaagt aaggaaaaac atggctaata ttttaaaaac aattatcgaa
     2581 aatgataaag gagaaatccg tcgtctggaa aagatggctg acaaggtttt caaatacgaa
     2641 gaccaaatgg ctgctttgac tgacgaccaa ctaaaagcaa aaacagttga atttaaggaa
     2701 cgttatcaaa atggagaatc actggattca ttgctttacg aagcatttgc ggttgtccgt
     2761 gaaggtgcca aacgtgtcct aggtctcttc ccttataagg ttcaggtcat gggggggatt
     2821 gttcttcacc atggtgacgt gccagagatg cgtacagggg aagggaaaac cttgactgcg
     2881 accatgccgg tatacctcaa tgccctttca ggtaaagggg ttcacgtagt tacggttaat
     2941 gaatacctgt cagaacgtga cgcgactgag atgggtgaat tgtactcttg gcttggtttg
     3001 tcagtaggga ttaacttggc taccaaatct ccaatggaga aaaaagaagc ctatgagtgt
     3061 gatattactt actcaactaa ctcagaaatc ggatttgact accttcgtga caacatggtc
     3121 gttcgcgccg aaaacatggt acaacgtccg cttaactatg ccttggtcga tgaggttgac
     3181 tctatcttga ttgacgaggc tcgtacacct ttgattgtat caggtgccaa tgcggttgaa
     3241 accagtcagt tgtatcacat ggcagaccac tatgtaaaat ctttgaacaa agatgactac
     3301 atcatcgatg tgcagtctaa gactattggt ttgtctgatt cagggattga cagggctgaa
     3361 agctacttca aacttgaaaa cctctatgac atcgaaaacg tggctttgac tcactttatc
     3421 gataacgccc ttcgtgccaa ctacatcatg cttctcgata ttgactatgt ggtgagcgaa
     3481 gagcaagaaa tcttgattgt cgaccaattt acaggtcgta ccatggaagg tcgtcgttat
     3541 tctgatggat tgcaccaagc tattgaagcc aaagaaggtg tgccaatcca ggatgaaacc
     3601 aagacatctg cctcaatcac gtaccaaaac ctcttccgta tgtacaagaa attgtctggt
     3661 atgacgggta caggtaagac tgaggaagaa gaatttcgtg aaatctacaa cattcgtgtt
     3721 attccaatcc caacaaaccg tcctgttcaa cgtattgacc actcagacct tctttatgca
     3781 agtatcgaat ctaagtttaa agcggttgtc gaagacgtta aggctcgtta ccaaaagggt
     3841 caacctgtct tggttggtac agtagcggtt gaaactagtg actacatttc taagaaattg
     3901 gtcgcagctg gtgttcctca cgaagtcttg aatgccaaaa accactatag agaagcccaa
     3961 atcatcatga atgctggtca acgtggtgcc gttaccatcg caaccaacat ggcgggtcgt
     4021 ggtaccgaca tcaagcttgg tgaaggtgtt cgtgaacttg gaggactttg tgttattggt
     4081 acagaacgtc atgaaagtcg tcgtatcgat aaccagcttc gtggacgttc aggtcgtcaa
     4141 ggagatccag gtgagtcaca attctaccta tctcttgaag atgatttgat gaaacgtttt
     4201 ggttctgaac gcttgaaggg aatctttgaa cgcttgaaca tgtctgaaga ggcgattgag
     4261 tctcgcatgt tgacgcgtca ggttgaagca gctcagaaac gtgtcgaagg aaataactac
     4321 gatacccgta aacaagtcct tcaatacgat gatgtcatgc gtgaacaacg tgagattatc
     4381 tatactcaac gttacgatgt catcactgca gatcgtgact tggcacctga aattcagtct
     4441 atgattaagc gcacgattga acgtgtcgtt gatggtcatg cgcgtgccaa acaagatgaa
     4501 aaactagagg caattttgaa ctttgctaag tacaacttgc ttcctgaaga ttctattacg
     4561 atggaagact tgtcaggctt gtctgataag gccatcaagg aagagctttt ccaacgtgcc
     4621 ttgaaggttt acgatagtca ggtttcaaaa ctacgcgatg aagaagcagt taaagaattc
     4681 caaaaagttt tgattctacg agtggtggat aacaagtgga cagatcatat cgatgccctt
     4741 gatcaattgc gtaacgcggt tggacttcgt ggctatgctc agaacaaccc tgttgttgag
     4801 tatcaggcag aaggtttccg tatgtttaat gatatgattg gttcgattga gtttgatgtg
     4861 acacgcttga tgatgaaagc acaaattcat gaacaagaaa gaccacaggc agaacgtcat
     4921 atcagtacaa cagcgactcg caatatcgct gctcaccaag caagtatgcc agaagatttg
     4981 gatttgagcc agattggacg caatgaactt tgcccatgtg gttctggtaa gaaatttaaa
     5041 aactgtcacg gtaaaagaca ataaaatgag atagtttaga ggcggatatc ttgtgaaaag
     5101 taaattttta ctgggtatcc gtttgcttta taaggagatg agttatggta tttacagcaa
     5161 aaagctctaa aataaatata gaagaagttc gtgccttgtc aaaattagaa ggtcaggctt
     5221 tggagaggaa atcacagcga gatcaagagc tagaagccat tatacgtgga gaagaccagc
     5281 gaattctctt ggtaatcggg ccatgctcat ctgacaacga agaagctgtc cttgaatacg
     5341 ctaagcgttt ggcagtccta caagaagaag tggcagatcg tatctttatg gttatgcgtg
     5401 tttatactgc caaaccccgt accaacggag atggctataa gggcttgatt caccagccta
     5461 acgcgacaga agcgcctagt cttatcaatg gaatcaaagc cgttcgccat cttcactatt
     5521 gtgtcatcac agaaacaggg atgacaactg ctgatgaaat gctttatcct gaaaaccttc
     5581 cgcttgtaga tgatttgatt tcttacatgg cagttggtgc ccgttcagtt gaagaccagc
     5641 aacaccgctt tgtggcaagt ggggcaggat tttctactgg ttttaaaaat ccaacctctg
     5701 gaaatctcaa tgtcatgttt aatgggattt atgctgctca aaacaaacaa agtttccttt
     5761 tcttaggaaa agaagtagaa acaactggga acccgctttc acacgctatt cttcgtggtg
     5821 ctcttaatga gtatggaaaa aatattccca actactatta tgacaattta attgatacca
     5881 ttgcccagta tgagaaaatg ggcttggaaa atccttttat catcattgat accaatcatg
     5941 acaattctgg taagcagtat attgaacaga tccgaattgt ccgccagacc ttgattaacc
     6001 gtgcttggaa tgaaaaaatt aagcagttcg ttcgtggttt tatgattgag tcttatctgg
     6061 aaaatggtcg acaaaatgag ccagaagtat ttggtaagtc tatcacagac ccttgcctgg
     6121 gttgggataa cacagaagct cttgtcagag aaatttacaa aacgttagga gaataagatg
     6181 gcatttattg aaaaaggtca agaaatcgat atggaagtca tcaaggctga aacccaattg
     6241 tctgcggaag ccttgagact caaggaaagc cgtgacaggg aattggcaga tattatttca
     6301 ggggaagatg accgtattct cttggtgatt ggtccttgct cttctgataa tgaagaggcg
     6361 gtcttggaat atgctcgccg tttatccgcc ttgcaaaaga aggtagcgga caagattttc
     6421 atggtcatgc gcgtgtatac tgctaagcct cgtaccaatg gagacggcta taaaggatta
     6481 gttcaccagc cagatacttc taaggctcca agcctgatta atggcttgca ggctgtgcgc
     6541 cagttgcact accgcgtgat tacagagact ggtttgacaa cggcagatga gatgctttat
     6601 ccgtcaaatc tgatcttggt ggatgacttg gtcagctacc atgccgttgg agctcgttct
     6661 gtggaagacc aagagcaccg ctttgtggct tctgggattg atgcaccagt agggatgaaa
     6721 aatccaacct caggaaattt gggtgttatg tttaacgcca tctatgctgc tcaaaacaag
     6781 caaaccttcc tttatcatgg gcaggaagtt gagacatcag gtaatccttt ggcccatgtt
     6841 atcctccgtg gagcagtcaa cgagtatggc aattatatgc cgaattacta ctatgaaaac
     6901 ctactccaag ccattgaacg ctatgaaacc atgggacttg aaaatccttt tatcctcatt
     6961 gacaccaacc atgataactc aggcaagcaa tatatggagc agattcgaat tgttcgccag
     7021 accttgcaga atcgtgattg gaatgagaaa attaaaaaga cggttcgagg atttatgatt
     7081 gaatcttacc tagcagatgg tcgtcaaaac caaccagaga tctttggttg ctctattact
     7141 gacccttgcc taggttggga aaatacagag gccttggtag aagagattta tgttaccttg
     7201 acaaaataag tgaaaaggat ggagttgggg aatctcaact ccttttgatg agaatgatag
     7261 ttggacacgg aattgacatc gaagaattgg cttcgataga aagcgcagtt acacgacatg
     7321 aaggatttgc taagcgtgta ctgaccgctc aggaaatgga gcgcttcacc agtctcaaag
     7381 gacgcaggca aatagaatat ttagctggtc gctggtcggc taaggaggcc ttttccaagg
     7441 ctatgggaac gggcattagc aagctcggtt ttcaggattt ggaagtcttg aacaatgaac
     7501 gtggggcgcc ttattttagt caggcaccat tttcaggaaa gatttggctg tctatcagcc
     7561 acaccgatca gtttgtgaca gccagtgtca ttttggagga aaatcatgaa agctagtcca
     7621 catagaccaa ccaaggctct gattcatctg ggagctattc gacaaaatat tcagcaaatg
     7681 ggggctcata tccctcaagg aacgctcaag ttggctgtgg ttaaggccaa tgcttatggt
     7741 catggagctg ttgccgttgc caaggcaatt caagatgatg ttgatggctt ttgcgtttcc
     7801 aatatcgatg aagccattga actcagacaa gctggactca gcaagccaat cctcatttta
     7861 ggagtttctg aaatcgaagc tgttgctcta gctaaagaat atgacttcac cttgacagtg
     7921 gctggactgg agtggattca agcactctta gataaggaag tggacctaac tggattgaca
     7981 gtccacctca agattgattc agggatggga cggattggtt ttagagaggc aagtgaggtt
     8041 gagcaggctc aagatttgct ccaacaacac ggtgtttgtg ttgaaggaat ctttacccac
     8101 tttgctactg ctgatgagga atcagatgac tattttaatg cccagttaga acggtttaaa
     8161 actattttag ctagtatgaa ggaagttcca gagctggttc atgctagcaa ttctgcaacg
     8221 actctttggc atgtagagac tattttcaat gcggttcgta tgggagatgc catgtatggt
     8281 ctcaatccaa gtggagcggt cttggatttg ccttatgatt tgataccggc cttgaccttg
     8341 gagtctgctc tggttcatgt caagacagtt ccagctggag cttgcatggg ctatggagca
     8401 acttatcaag cggatagcga gcaagtcatc gcaaccgtgc caatcgggta tgcagatgga
     8461 tggacaagag acatgcaaaa tttctctgtc ttggtagatg gccaagcttg cccaattgtc
     8521 ggcagggttt cgatggacca aatcactatt cgattgccta agccttaccc actcggaacc
     8581 aaggtaacct tgattggctc caatggggat aaggaaatca ctgcaactca ggtagcgacc
     8641 taccgcgtaa ccattaacta tgaggtggtt tgccttctca gcgaccgtat tccgagagaa
     8701 tattattaga aaagaaagga gtggagcatg aatctacatc aacccttgca tgtcttgcct
     8761 ggtgtgggac caaagtcagc agaaaaatac gccaaactag gaattgaaaa cttgcaagat
     8821 ctcttgctct actttccttt ccgttatgaa gacttcaaaa ccaagcaggt gctggagctg
     8881 gaagacggtg agaaggcagt tctttctggt caggtagtga ctcctgctag tgtccagtat
     8941 tatggtttca agcgcaatcg cctgcgtttt agtctcaagc agggagaggt cgtttttgcg
     9001 gtgactttct ttaaccagcc ctatctggct gataaaatag agttgggagc aacccttgct
     9061 gtctttggaa aatgggaccg cgctaaggct agtctgactg ggatgaaggt tctggctcag
     9121 gtagaagatg acctccagcc tgtttatcgt ctggctcagg gaatcagtca ggccagtctg
     9181 gttaaggtca tcaagacggc ttttgatcag ggactggacc tcttgataga agaaaatctg
     9241 ccccagtctt tactagacaa atacaaactc atgtcccgtt gtcaggcagt ccgagctatg
     9301 cattttccaa aggatttggc agaatacaag caggctcttc gccgtataaa gtttgaggaa
     9361 ctcttttatt tccaaatgca gctgcagatg ctcaagtctg aaaatagagt tcagggaagt
     9421 ggtctggttc tgaattggtc tcaggaaaaa gtgacagcag ttaaagtaag tcttcctttt
     9481 gccctgaccc aagctcagga aaagagtttg caggaaattt taactgatat gaagtccgac
     9541 caccacatga atcgtctcct acaaggggat gtggggagtg gaaaaacggt agtcgctggc
     9601 ttggccatgt ttgcggcagt gacagcaggt tatcaggctg ccctaatggt accaacagaa
     9661 atcctcgcag agcaacactt tgagagttta cagaaccttt ttcccaattt gaaactggct
     9721 ctcttgacag gttccttgaa agctgcagaa aagagagaag tcttggagac cattgccaag
     9781 ggtgaggctg atttgattat aggaactcac gctctgatac aagatggggt ggagtatgct
     9841 cgtcttggtt tgattattat cgatgagcag caccgttttg gtgtagggca aaggcgtatt
     9901 ttacgggaaa aaggtgacaa tccagatgtc ctcatgatga cggcgactcc cattccacgg
     9961 acgcttgcca tcacagcctt tggagatatg gatgtttcca ttatcgacca gatgccagca
    10021 ggtcggaagc ctattgtgac gcgctggatc aaacatgagc aactacctca ggtcttgact
    10081 tggttagagg gggaaattca aaaaggttcc caagcctatg tcatctctcc tttgattgaa
    10141 gaatcagaag ctctagattt gaaaaatgcc attgccttat cagaagagct gacggctcat
    10201 tttgcaggca aggcagaggt ggctcttcta catggtagga tgaagagtga cgaaaaagac
    10261 cagatcatgc aggatttcaa ggagagaaag acggatattc tggtttcgac gacggttatt
    10321 gaggttgggg tcaacgttcc caatgcgact gtcatgatta tcatggatgc cgatcgcttc
    10381 gggctcagcc agcttcacca gcttagaggt cgtgtcggtc ggggggacaa gcagtcctac
    10441 gctgttctcg ttgccaatcc caagacggat tctgggaaag accgcatgcg catcatgaca
    10501 gaaacgacca atggatttgt ccttgcggag gaagatttga aaatgcgtgg ttctggtgag
    10561 atttttggaa ccagacagtc aggacttcca gagttccaag tggctgatat tatcgaagat
    10621 tttccgattt tagaagaagc aagaaaggtt gctagctaca ttagttctat agaagcttgg
    10681 caagaagatt cagagtggcg catgattgcc cttcatctgg aaaagaaaga acatctggat
    10741 taagctttct ctaaggaaaa cttaagctag tttttaggtt tggctcttat actaaagtca
    10801 tcaaaaagaa acgaggactc tcatatgaca gtaacgatta aagtaaatta ccaaaccact
    10861 ttccaaaaga aggaagcaaa aaactagtat aaacagaaga gagagcgaaa tgctcttttt
    10921 cgtttctaaa actactttca gcccatcatc ctaaaagtaa agaatctaaa ttcactttct
    10981 atttatcctt ctttcttgca ttgattacat agatatgcta cagttgtggt aacgattaca
    11041 aaataaaagg agcatgctat gaaaaatcca gctttgctag aagaaattaa gacctataga
    11101 ggaagggatg aggttccgga agactttgat gctttctggg atggggaagt gaaaaatgtt
    11161 tccacgcttc catcctacca cttggaggaa agagatttcc acattcctca agtcaagtgc
    11221 tatgagttaa catttgaagg aagcaaggaa ggaaaggtct atgcacgcat tgttcttcca
    11281 aagagtgagg agaaggttcc actaatattc cattttcatg gttatatggg acgtggctgg
    11341 gactgggccg acatgctggg cttcaccgta gctggttacg gtgttgtttc catggatgtg
    11401 cggggccagt caggttactc acaagacggc ttgcgttctc ctttaggaaa taccgtgaag
    11461 gggcatatta tccgtggtgc tatggaaggt cgggaccacc tcttttataa ggatgtttat
    11521 ctggatattt accagttggt cgaaattgtt gctagtctgt ctcaggttga tgagaagcgt
    11581 ctttctagct atggtgcctc acaaggaggg gctctagctc tagttgcagc agcgctcaat
    11641 cctcgaattc agaaaacagt tgccatttat cccttcttgt cagacttcag acgggtgatt
    11701 gagattggta atactagcga ggcttacgac gaacttttcc gttatttcaa gtttcacgac
    11761 cccttccatg aaacagagga ggaaatcatg gcgacccttg cctatatcga tgtcaaaaat
    11821 cttgcccatc gtatccaagg tgaggttaag atgattacgg gcttggacga cgatgtttgc
    11881 tatcccatta cccagtttgc gatttataat cgtctgacct gcgataaaac ctatcgcatc
    11941 atgcctgagt atgctcacga agccatgaat gtatttgtca atgaccaagt ctacaactgg
    12001 ctctgtggaa gtgagattcc ttttaaatat ctaaaataag gagtcgactc taagcacaaa
    12061 atcttaaaaa ttacaaacac gcatagtatc aggggcttaa gaaaacttga tactatgcgt
    12121 tttatcatgg aaatatagta aaatgaaaca agaacagggc aaatcgatca ggacagtcaa
    12181 atcgatttct aacaatgttt tagaagtaga tgtgtactat tctagtttca atctatatta
    12241 tatttataga attttttgtt gctagatttg tcaaattgct taaaataatt tttttcagaa
    12301 agcaaaagcc gatacctatc gagtagggta gttcttgcta tcgtcaggct tgtctgtagg
    12361 tgttaatact tttcaaaaat ctcttcaaac cacgtcagct tcgccttgcc gtatatatgt
    12421 tactgacttc gtcagttcta tctgccactt caaaacggtg ttttgagctg acttggtcag
    12481 ttctatctgc cacttcaaaa cggtgttttg agctgacttc gtcagttcta tccacaacct
    12541 caaaacagtg ttttgagcat catgcggcta gtttcttagt ttgctctttg attttcattg
    12601 agtataaaaa cagatgagtt tctgttttct ttttatggac tataaatgtt cagctgaaac
    12661 tactttcaag gacattatta tataaaagaa ttttttgaaa ctaaaatcta ctatattaca
    12721 ctatattgaa agcgttttaa aaatgaggta taataaattt actaacgctt ataaaaagtg
    12781 atagaatcta tctttatgta tatttaaaga tagattgctg taaaaatagt agtagctatg
    12841 cgaaataaca gatagagaga agggattgaa gcttagaaaa ggggaataat atgatattta
    12901 aggcattcaa gacaaaaaag cagagaaaaa gacaagttga actacttttg acagtttttt
    12961 tcgacagttt tctgattgat ttatttcttc acttatttgg gattgtcccc tttaagctgg
    13021 ataagattct gattgtgagc ttgattatat ttcccattat ttctacaagt atttatgctt
    13081 atgaaaagct atttgaaaaa gtgttcgata aggattgagc aggaagtatg gtgtaaatag
    13141 cataggctga tgtccatcat ttgcttataa agagatattt tagtttaatt gcagcggtgt
    13201 cctggtagat aaactagatt ggcaggagtc tgattggaga aaggagaggg gaaatttggc
    13261 accaatttga gatagtttgt ttagttcatt tttgtcattt aaatgaactg tagtaaaaga
    13321 aagttaataa aagacaaact aagtgcattt tctggagtaa atgtcttatt tcagaaatca
    13381 ggatatagat atagagagga tcagtatgaa tcggagtgtt caagaacgta agtgtcgtta
    13441 tagcattagg aaactatcgg taggagcggt ttctatgatt gtaggagcag tggtatttgg
    13501 aacgtctcct gttttagctc aagaaggggc aagtgagcaa cctctggcaa atgaaactca
    13561 actttcgggg ggggggagct caaccctaac tgatacagaa aagagccagc cttcttcaga
    13621 gactgaactt tctggcaata agcaagaaca agaaaggaaa gataagcaag aagaaaaaat
    13681 ttcaagagat tactatgcac gagatttgga aaatgtcgaa acagtgatag aaaaagaaga
    13741 tgttgaaacc aatgcggcaa atggtcagag agttgattta tcaagtgaac tagataaact
    13801 aaagaaactt gaaaacgcaa cagttcacat ggagtttaag ccagatgcca aggctccagc
    13861 attctataat ctcttttctg tgtcaagtgc tactaaaaaa gatgagtact tcactatggc
    13921 agtttacaat aatactgcta ctctagaggg gcgtggttcg gatgggaaac agttttacgg
    13981 taattacaac gatgcaccct taaaagttaa accaggtcag tggaattctg tgactttcac
    14041 agttgaaaaa ccgacaccag aactacctaa aggccgagtg cgcctctacg taaacggggt
    14101 attatctcga acaagtctga aatctggcaa tttcattaaa gatatgccag atgtaacgca
    14161 tgtacaaatc ggagcaacca agcgtgccaa caatacggtt tgggggtcaa atctacagat
    14221 tcggaatctc actgtgtata atcgtgcttt aacaccagaa gaggtacaaa aacgtagtca
    14281 actttttaaa cgctcagatt tagaaaaaaa actacctgaa ggagcggctt taacagagaa
    14341 aacggacata ttcgaaagcg ggcgtaacgg taaaccaaat aaagatggaa tcaagagtta
    14401 tcgtattcca gcacttctca agacagataa aggaactttg atcgcaggtg cagatgaacg
    14461 ccgtctccat tcgagtgact ggggtgatat cggtatggtc atcagacgta gtgaagataa
    14521 tggtaaaact tggggtgacc gagtaaccat taccaactta cgtgacaatc caaaagcttc
    14581 tgacccatcg atcggttcac cagtgaatat cgatatggtg ttggttcaag atcctgaaac
    14641 caaacgaatc ttttctatct atgacatgtt cccagaaggg aagggaatct ttggaatgtc
    14701 ttcacaaaaa gaagaagcct acaaaaaaat cgatggaaaa acctatcaaa tcctctatcg
    14761 tgaaggagaa aagggagctt ataccattcg agaaaatggt actgtctata caccagatgg
    14821 taaggcgaca gactatcgcg ttgttgtaga tcctgttaaa ccagcctata gcgacaaggg
    14881 tgatctatac aagggtaacc aattactagg caatatctac ttcacaacaa acaaaacttc
    14941 tccatttaga attgccaagg atagctatct atggatgtcc tacagtgatg acgacgggaa
    15001 gacatggtca gcgcctcaag atattactcc gatggtcaaa gccgattgga tgaaattctt
    15061 gggtgtaggt cctggaacag gaattgtact tcggaatggg cctcacaagg gacggatttt
    15121 gataccagtt tatacgacta ataatgtatc tcacttaaat ggctcgcaat cttctcgtgt
    15181 catctattca gatgatcatg gaaaaacttg gcatgctgga gaagcggtca acgataaccg
    15241 tcaggtagac ggtcaaaaga tccactcttc tacgatgaac aatagacgtg cgcaaaatac
    15301 agaatcaacg gtggtacaac taaacaatgg agatgttaaa ctctttatgc gtggtttgac
    15361 tggagatctt caggttgcta caagtaaaga cggaggagtg acttgggaga aggatatcaa
    15421 acgttatcca caggttaaag atgtctatgt tcaaatgtct gctatccata cgatgcataa
    15481 tggaaaagaa tacattatcc tcagcaatgc aggtggaccg aatcgtgaaa atgggatggt
    15541 ccacttggca cgtgtcgaag aaaatggtga gttgacttgg ctcaaacaca atccaattca
    15601 aaaaggagag tttgcctata attcgctcca agaattagga aatggggagt atggcatctt
    15661 gtatgaacat actgaaaaag gacaaaatgc ctatacccta tcatttagaa aatttaattg
    15721 ggaatttttg agcaaagatc tgatttctcc taccgaagcg aaagtgaagc gaactagaga
    15781 gatgggcaaa ggagagatgg gcaaaggaga gatgggcaaa ggagttattg gcttggagtt
    15841 cgactcagaa gtattggtca acaaggatcc aacccttcaa ttggcaaatg gtaaaacagc
    15901 gactttccta acccagtatg atagcaagac cttgttgttt gcagtagata aggaagatat
    15961 cggacaggaa attattggta tagctaaagg aagcatcgaa agtatgcata atcttcctgt
    16021 aaatctagca ggtgccagag ttcctggcgg agtaaatggt aacaaagcag cggtgcatga
    16081 agttccagaa tttacagggg gagttaatgg tacagagcca gctgttcatg aaatcgcaga
    16141 gtataaggga tctgattcgc ttgtaactct tactacaaaa gaagattata cttacaaagc
    16201 tcctcttgct cagcaggcac ttcctgaaac agggaacaag gagagtgacc tcctagcttc
    16261 actaggacta acagctttct tccttggtct gtttacgcta gggaaaaaga gagaacaata
    16321 agagaagaat tctaaacatt tgattttgta aaaatagaag gagatagcag gttttcaagc
    16381 ctgctatctt tttttgatga cattcaagct gatacgaaat cataagaggt ctgaaactac
    16441 tttcagagta gtctgttcta taaaatatag tagattgaaa taagatgtga acaactctat
    16501 caggaaagtc aaattaattt atagaaaaat tttagcagtc aaggtgtact gttatagatt
    16561 caatatatta tgtgactatt aaccttctct tctcctaaaa ttgactttct tgttttctta
    16621 tcttgtccac tcgaaacaag tattgtaaga atttgattat ttttgaaagt acttttaata
    16681 tacttgatat agttaaaaaa gatttgaaac taaattccaa attagaaaaa gacttgaaat
    16741 actaaaaaaa aaaaagtata ctctaattga aaacggtaac aaaactaatt tagagaatga
    16801 aatatagagt atttctctct taaaagtttt tggtgaaacg agatgtagaa aggagattta
    16861 gccaaagagt ctattagtgc tagaataata gattagaatt attttagaaa aacgaagtga
    16921 gcagcttata aattcaagtc cccaaataga ttcatactag tatcttttgc aaaaaataaa
    16981 gggcgacttc cttcatgaat atcaatttca tctataagga aggtagctaa ttgaactaac
    17041 ttatttattc tgtttgtcgc tagaaaaatc agacctcctt gtgaagattg aggagatact
    17101 gaatgaaaat caaagaagaa actagcaagc tagtagcaga ttgcccaaaa caccgctttg
    17161 aggttgtaga taagactgac ctatataatc caaggtgaag cgactgtggt ttgaagagat
    17221 tttcaaagag tataggctag agagtagtgt ttttatgtcc ttctagtaga aaatgctaga
    17281 cagaagaatg gggaacttgg ataggagaaa tagattgaga aaggaggtta gaagagatga
    17341 ttattacaaa aattagccgt ttaggaactt atgtgggagt aaatccacat tttgcaacat
    17401 taatagattt tctagaaaaa acaggactag aaaatttaac agaaggttcg attgctatcg
    17461 atggtaatcg attgtttggg aattgcttta cttatctagc agatggtcaa gcaggggctt
    17521 tctttgaaac acaccaaaaa tatttggata ttcatttagt tttggaaaac gaagaagcca
    17581 tggctgttac atcgccggaa aatgtaagcg ttacccaaga atatgatgaa gagaaggata
    17641 t
//
LOCUS       DAVDFK010000038        16878 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.38, whole genome shotgun sequence.
ACCESSION   DAVDFK010000038 DAVDFK010000000
VERSION     DAVDFK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.38"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            132..1466
                     /gene="pepC"
                     /locus_tag="VUR04_001632"
     CDS             132..1466
                     /gene="pepC"
                     /locus_tag="VUR04_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET5341504.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(1522..2433)
                     /locus_tag="VUR04_001633"
     CDS             complement(1522..2433)
                     /locus_tag="VUR04_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5341505.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2457..3260)
                     /locus_tag="VUR04_001634"
     CDS             complement(2457..3260)
                     /locus_tag="VUR04_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET5341506.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(3288..4277)
                     /gene="manX"
                     /locus_tag="VUR04_001635"
     CDS             complement(3288..4277)
                     /gene="manX"
                     /locus_tag="VUR04_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET5341507.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(4510..5529)
                     /gene="adhP"
                     /locus_tag="VUR04_001636"
     CDS             complement(4510..5529)
                     /gene="adhP"
                     /locus_tag="VUR04_001636"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET5341508.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(5868..6680)
                     /locus_tag="VUR04_001637"
     CDS             complement(5868..6680)
                     /locus_tag="VUR04_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5341509.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            6870..8288
                     /locus_tag="VUR04_001638"
     CDS             6870..8288
                     /locus_tag="VUR04_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET5341510.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8341..9048
                     /locus_tag="VUR04_001639"
     CDS             8341..9048
                     /locus_tag="VUR04_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5341511.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            9165..10139
                     /gene="folP"
                     /locus_tag="VUR04_001640"
     CDS             9165..10139
                     /gene="folP"
                     /locus_tag="VUR04_001640"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET5341512.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            10141..11463
                     /locus_tag="VUR04_001641"
     CDS             10141..11463
                     /locus_tag="VUR04_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET5341513.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLVLRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRVYLMERKNENGYTKD"
     gene            11444..11998
                     /gene="folE"
                     /locus_tag="VUR04_001642"
     CDS             11444..11998
                     /gene="folE"
                     /locus_tag="VUR04_001642"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET5341514.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12041..12853
                     /gene="folK"
                     /locus_tag="VUR04_001643"
     CDS             12041..12853
                     /gene="folK"
                     /locus_tag="VUR04_001643"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET5341515.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(13003..13320)
                     /locus_tag="VUR04_001644"
     CDS             complement(13003..13320)
                     /locus_tag="VUR04_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET5341516.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            13676..14122
                     /gene="rplM"
                     /locus_tag="VUR04_001645"
     CDS             13676..14122
                     /gene="rplM"
                     /locus_tag="VUR04_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET5341517.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14141..14533
                     /gene="rpsI"
                     /locus_tag="VUR04_001646"
     CDS             14141..14533
                     /gene="rpsI"
                     /locus_tag="VUR04_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET5341518.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(14796..15200)
                     /locus_tag="VUR04_001647"
     CDS             complement(14796..15200)
                     /locus_tag="VUR04_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5341519.1"
                     /translation="MLFFSISNDLLQLLISWEKQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAEMSLEAISEALT
                     HSDTVTTKTYVNTSNIVPLSAGQVAYQHLKNK"
     gene            complement(15573..16781)
                     /locus_tag="VUR04_001648"
     CDS             complement(15573..16781)
                     /locus_tag="VUR04_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5341520.1"
                     /translation="MNYIKRPHYLDFLRRHRDRPIIKVVSGVRRAGKSVLFQLYKEEL
                     LATGVDEDQIIFINFEDLSYYDLRHFQTLFAYIKDQLVSKKTYYIFLDEIQYVEKFEL
                     VADSLFILANVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYDEKIDYLRGIYNSILLNDIVTRLGKPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDHKEDIRHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLEAIKDQFPKYLLTMDTIHPTANYNGIEK
                     KNIIDWLLEK"
BASE COUNT         4920 a         3269 c         3633 g         5056 t
ORIGIN      
        1 tggtttgaat ttgattttcg aagagtataa attcgaaaaa ggtgagggac aatgtcctcg
       61 ccttttatgt tttttagttg cttcctttgt gaaaagagtt ataatagact gtagaataaa
      121 aggaggaatc tatgaacgcg attcaagaat catttactga taaactattt gccaactatg
      181 aagcaaatgt aaaataccaa gcgattgaaa atgctgctag ccacaacgga atttttgcag
      241 ctctggaacg tcgccaaagc catgtagaca acacacctgt tttctcattg gatttaacca
      301 aggacaaggt cactaaccag aaagcgtctg gtcgttgctg gatgtttgcg gctctcaaca
      361 ccttccgcca caaactcatc tcgcaataca aattggagaa ctttgagttg tcacaagccc
      421 acactttctt ctgggacaag tatgagaaat caaactggtt cttggagcaa gtcattgcga
      481 cttcagacca agaattgact agccgcaagg ttagcttctt acttcaaaca cctcaacaag
      541 atggcggtca atgggatatg gtcgtttccc tctttgaaaa atacggtgtc gtgcctaagt
      601 cagtttatcc tgagtctgtt tcatctagca gcagtcgtga gctaaatgcg atccttaata
      661 aattgcttcg tcaagatgct caaatcttgc gtgacttgct tgtttctggt gcagatcaag
      721 cgactgttca agctaagaaa gaagacctct tgcaagaaat ctttaacttt cttgctatgt
      781 cattaggact tccaccacgc aagtttgact ttgcttatcg cgataaagat aacaactaca
      841 aaagtgaaaa aggaattaca ccacaagagt tttacaagaa atatgtcaat cttcctttag
      901 aagactacgt ttctgttatc aatgctccaa ctgctgataa accttacgga aaatcttaca
      961 cagttgagat gttggggaat gtggttggta gccgtgcagt tcgctacatc aacgttccaa
     1021 tggagcgctt gaaagaattg gcgattgccc aaatgcaagc aggtgagact gtttggtttg
     1081 gttctgatgt cggccagctc agcaaccgta aggctggcat ccttgcgaca gatgtttatg
     1141 actttgaatc aagcatggac attaaactta ctcaagacaa ggctggacgt ttagactata
     1201 gcgaaagctt gatgacccac gccatggtct tgacaggtgt tgacttggac gaaaatggta
     1261 aatcaaccaa gtggaaggtt gaaaactcat ggggagacaa ggtcggtaca gatggttact
     1321 ttgttgcctc agacgcttgg atggacgaat acacatacca aatcgttgtt cgtaaggaat
     1381 tgctgacagc agaagaacaa gctgcctatg gagcagaacc aattgtactt gcaccatggg
     1441 atccaatggg agccttggct gaataaaagc atagaaaaaa ggaatcagat tttagaacct
     1501 ggttcctttt tagttgcttg attacatgat gtgaagaaca tgtgccacaa tacccactgc
     1561 gaagagggca aggataatag tgattggaga tacttttttc ttaagtaagt acatgcaaag
     1621 taaagtaagg agtagtcctg ataatccagg aatcaacata tccaagtttt gttggaaagt
     1681 agtaactttt tcaggagttt gagacaatcc ttgtcctact tgtgcgaatg cttcttggat
     1741 acctttagac ccttctggca atttatccca atggatataa gccttttcat ctagttgaac
     1801 tttagaaaca tcgaaagcaa atttaatatt tacccagcgt tgaacaagga cagcaagaat
     1861 gaacatccca aggatagaag ctcctttagt gatatcttga aggataccac cagacatatc
     1921 tttagtgatt tctgatccag ccttgtatcc aatctcttga acataccaca agaatgacat
     1981 acgaatcaag ttccatgcaa caaagaagag gagtggaccc aagatattgc cagtaagggc
     2041 aagtgaagca ccgagagatc caaggattgg gcgcactgta aaccagaata ctgggtcacc
     2101 gataccagca agaggtccca tcataccgat tttgacccct tggatagcag cgtcatcgat
     2161 ttccacaccg ttagcacgtt cttcttcaag cgcaagagta acccccatga ctggagcagc
     2221 tacgtatgga tgagtgttga agaactcaag gtgacgctca agagcagcga tttgatcttc
     2281 ttttttagta tagagttttt tgatagctgg aatgagtgta taagcccagc ccaagttttg
     2341 catccgttca aagttccaag acccttgtaa gaaggttgaa cgccaccaaa cttttttacg
     2401 atctgattta gttaattgaa gtttttcagt catgatgttt tcagtccttt cttatcttag
     2461 tagtcttcta ggatatcgcc gattgggtcg ttagaagttg cggctcctcc gccaccattt
     2521 ccaccagttt tagaaaggtg aaggtagata agagcgatag caacaccgat agcaccgaat
     2581 ccgattagag taatatctga cacagcagcg agaacgaaac caagagcgaa gaatggccat
     2641 acttcacgag ttgccatcat gttgataacc atggcgtaac caacggcaac gaccatacca
     2701 ccaccgatag ccataccatc tttgagccag tctggcatgg cactaaggat actttgtaca
     2761 gtttcagttg gtaccataag gagaagagct gcaggaagcg cgatacgaag tccttggaag
     2821 agtagcgcaa tgaaatgcgc acgctccaca gcgccgaagt cacctttttt agcggcagca
     2881 tctgcagtat gaaccaaacc aactgaaatt gtacgaacaa tcattgtcaa gaaaagtcca
     2941 gctacggcaa gagggatagc aaccgcttgg gcaacaccga taccagtctt ggtaaagtca
     3001 ccaccaagaa ccatgataat ggcagcagcg acagaagcaa gtgcagcatc aggagcgata
     3061 gcagcaccga tatttgacca accaagggca atcatttgaa gcgatccacc gaggataatc
     3121 cctgcttcca agtgacctgt tacaagccca ataagggtac aggctacaag tggttggtga
     3181 aattggaact ggtcgaggat gccttcaaga cctgcaaaga aggctacaac gactactaaa
     3241 accatagaaa taatagacat gtttaaaatc ctttcataaa taatggctta tttgacattg
     3301 gctttgttaa tcaagtcaaa caaatctttt ttagaatcat ttggtacttt acggacatca
     3361 aattcaacac ccaagtcacg cattttttca aatgtagcaa catcttcttt gtccatagac
     3421 aaaacggtat tgaccaatgt tttacctgtt gagtgagcca tagaaccaac gttaagagtc
     3481 ttgattggca cgccgccttc gatggcacga agggcatctt gaggtgtttc aaacaagata
     3541 agggcatgtg tttctccaaa acgtgggtct tttgaaatct caatcagttt ttgaattgga
     3601 accacgttag ccttgacatt acctggagct gcttgtttaa tcaattcttt acgaaggtcg
     3661 tctttagcca cgttatctga agcaacgatg atacgatttg cttttgaatc tggagtccaa
     3721 gcagttgcaa cctgaccgtg aagtagacgt gtgtcaagac gggcaagatt gattttcaat
     3781 ttaccgtctc cgataacagt tccttctggg atagcagctt gggcaactgg agcagctgca
     3841 gcgcttgcaa cttcttcaac tggatttagc tcttctggaa gagctttgat gccatctttg
     3901 gcttctttaa tgatattagc agcgactttt tctacacctg cagcagcgtc catgaggcgc
     3961 tctgtgtagg cttgaatcaa catcggtaag ttaagtcctg tgatgatggc aaacttacgc
     4021 tcaggatttt ctcccatcac gcgactagct tggttaaatg gagaaccact ccaaaggtca
     4081 gccaaaacta gaacctcatc ttctgcgtca aatgcagcaa cagcgttatt aaacttagcg
     4141 tatagatcat caggaccttc atttggcata aaggtcacaa cttgaacctt ttcttgttca
     4201 ccaaagatca tagatcctga ctgatgaata cccgcagcaa attcgccgtg gctcgcaata
     4261 atgattccga tactcattat tgtcattcct ccttttttgt tttagttttc atttaagaaa
     4321 actttaagac tgtttaagta taaaccgttt tcataaaaaa agcaactatt tatcataaaa
     4381 aattaaaaaa aatttatttt tgtatgttga tatgttgagt ttttgaggag taatcttgaa
     4441 ttcttattta aaatttaata taaaaaagtt ggaagaagct tccaactttt aaaataggtt
     4501 tctattagat tagtgggtga agtcgagtac catacgtcct tggatttgac ctttttccat
     4561 ttcgtcgaaa atggcaacag catcttctac tggacgtttt tgaacaactg gggctaccag
     4621 accttctgca ccaaattgga aggcttcttc taagtcttta cgagttccga caagagaacc
     4681 gatgacttgg attccatcga ggactgtttt aacgatgctg agttccatca tttcagaagg
     4741 aagaccaaca gcgacgacgc gaccaccagc acgaacggag tcaacagcct ggttgaaggc
     4801 aactttagac acagcagtta cgacagctga atgagctcct ccatcagttt tttctttgat
     4861 gagtccagct acatcttcaa cttcgaggcc gttaatcaca atgtcagcgc ctacttcttt
     4921 tgcaagggca agtttgtcat tgttgatatc gactgcgata acatgagcat tgaatacttt
     4981 tttagcgtat tgaacagcga ggttaccaag tccaccagca ccgtaaagaa caacccattg
     5041 gcctggttca acttttgctt ctttgatagc tttataggtt gttactccag cacatgttat
     5101 agaagaagct tgggctggat caagtccgtc aggaactttg acagcatagt cagcagttac
     5161 gatacattgt tcagccatac caccgtctac tgagtagcca gcatttttca ctgtacggca
     5221 aagggtttcg cgaccagttg tacagtattc gcaagtgcca catccttcaa agaaccaagc
     5281 aacgctgacg cggtcaccga ctttaaggct tttcacatct ggagcaatct ctttaacgat
     5341 accgatacct tcgtgcccaa gaacacgtcc tgggacttga ccaaagtcac catgagcaac
     5401 gtggaggtcg gtgtggcaaa cgccacagta ttcaacttct acaagtgctt ccccagtttc
     5461 aagtggacgg agtacttttt cttcaatagc aacaccagtg ctttctggat ttacaacaac
     5521 agctttcata gctatcctcc ttgatattga ccgagaacag ggacaacggg actggattga
     5581 ttttttgtca acagagtcga gtgtgacgag ctctcttgta tttatatgtg aagtatatca
     5641 caaaagaaag ccttttccaa ggttttggag acaaaaagta gaacaatcga ttaactggtt
     5701 gatgagactg tgaaaagagc acaaagacca gcttgcaagc tggtcatact cttcgaaaat
     5761 ctcttcaaac cacgtcagct tcatctacaa cctcaaagca gtgctttgag caacctacgg
     5821 ctagcttcct agtttgctct ttgattctca ttgagtatca gtgtaggcta taagaataag
     5881 tcttgtaggg ttttggcaac cccatcttgg tcgttggtaa gggaaatttg ctcatctgca
     5941 taagggagta gctctggatt ggcatttttc atggcataac ctttcccagc aaaagcgagc
     6001 atttcggtat cattgtgttc atctccaaag gcaatcaaat cttttttgtc acgattcatt
     6061 atcttgagca agtagtccaa agcaaaggcc ttgttgacac cttttggggt acattcaagg
     6121 atattgagcg gacctcccca ggtattgata gaaagttgat gctggtagaa ggcgttcatg
     6181 tcttttgcca aggcatattt gtcactggct ctggtctgca agaggataca gttagggtcc
     6241 ttggtcacca attcaggctg gaattgatct tcaggctgga aagcttctac accaaatagt
     6301 ttgggattgg caatttcttc attgggattt gtaatgtaga attttttacg atattctcca
     6361 gcgataaaat cggcttgaat gtcctctgaa cgttgaacca tatctagcag atattttttg
     6421 tctacagtca aacacttttc aaaatcccaa acttggtctg gtaaatgagt aagggatccg
     6481 ttgaagttaa tcataggagt gtctaagccc agttcacggt aaaaatcttt tgacatacgg
     6541 taagggcgac ctgtcgtaat aataacctga tggccttttt cagcaacttt tttgatggtt
     6601 cttttggtaa agtcagaaat ttgactgtct gagttgagca gggttccatc caggtcaact
     6661 gcaataattt ttttcgtcat atggaccttt ctagtgtgtt ttcagataag atgtcttcta
     6721 ttataacaga aagcaggcag aaaagcagat tccaaacaaa aaatgaaatt ggattaattt
     6781 cttaaacaaa tcaaacaaag acattgaaaa agtgaatgat aaatgatata attctattat
     6841 tgttcgtaaa aattaaaagg agattgatga tggacaaatt atttaaacta aaagagaacg
     6901 gtacagacgt tcgtacagag gttctcgctg gtttaacaac tttctttgca atgagctata
     6961 ttctctttgt aaacccacaa atactttcac aaacaggaat gcctgctcag ggcgtcttcc
     7021 tagcgacgat tattggtgca gtagcgggta ccctgatgat ggctttttat gctaacttac
     7081 cttatgccca agcgccaggt atgggactca atgctttctt tacctttaca gttgtattcg
     7141 ggcttggtta ttcttggcaa gaagccctag ctatggtctt catctgtggg attatttcat
     7201 tgattattac cttgacaaat gttcgtaaaa tgatcattga atcgattccc aatgctcttc
     7261 gctcagctat ttcagctggt atcggtgtct tccttgccta tgtagggatt aagaatgctg
     7321 gacttttgaa attcacgatt gatccaggca actatactgt tgtaggagaa ggggctgaca
     7381 aagctcaagc aacgattgca gcaaactctt cagcagttcc aggattggtc agctttaata
     7441 atccagctgt tttagtggct cttgcaggac ttgccattac tatcttcttt gtcatcaaag
     7501 ggattaaagg gggaattatt ctctctatct tgacaacaac tgttcttgct attgcagttg
     7561 gtttggttga tttgtctagt atcgattttg ctaataacca tgttggtgca gcttttgaag
     7621 atttgaagac aatctttggt gcagctcttg gttcagaagg tttgggagct ttggtttcag
     7681 atacagctcg cttgcctgaa actctgatgg ccattcttgc cttctcattg acagatattt
     7741 ttgacacaat tggtaccttg atcggtacag gtgaaaaagt tggtattgta gcgacaaatg
     7801 gtgaaaatca ccaatcagcc aaattggata aggctcttta ctctgatttg attggaacga
     7861 cagtcggtgc cattgcaggt acttcaaacg taacgactta tgttgagtct gctgctggta
     7921 tcggtgcagg tggacgtact ggtttgacag ccttggttgt agctatctgt tttgcgattt
     7981 caagcttctt tagcccgctt ctagcgatcg taccaacagc ggctacagct ccaatcttga
     8041 ttatcgttgg gattatgatg cttggtagct tgaaaaatat ccattgggat gatatgtctg
     8101 aagcagttcc tgccttcttc acatctatct ttatgggatt cagctactct atcactcaag
     8161 ggattgcagt tggtttcttg acttacactt tgactaagct tgtcaaaggt caagttaaag
     8221 atgttcatgc catgatttgg attttggatg ccttgtttat ccttaactac atcagcatgg
     8281 ccttataata gaatgactca gggggatttc cccctttttt taatacaaag gagataggtg
     8341 atgaaagaga aaaatatgtg gaaagaattg ttgaatcgtg caggctggat tttggtcttt
     8401 ttacttgccg tccttttata tcaggttccc ctagtggtta cctctatttt gactttaaaa
     8461 gaagtagccc tgctacagtc agggctgata gttgctggcc tttcaattgt ggttctggct
     8521 ctatttatta tgggagctcg taaaaccaag ttagctagtt ttaatttttc tttttttaga
     8581 gctaaagatt tggcacgttt gggcttgagt tatttagtta ttgtcgggtc aaatatactt
     8641 ggttctatct tgttgcaact gtcaaatgag acgacaacag ctaaccagtc tcagattaac
     8701 gatatggttc aaaatagttc gttgatttcc agtttcttct tgctagcctt gcttgctccg
     8761 atttgtgagg aaatcttgtg ccgtgggatt gttcctaaaa agattttccg aggcaaggag
     8821 aacttgggat ttgtagtcgg tacgattgtg tttgctttat tgcatcaacc aagtaattta
     8881 ccttctttat tgatttatgg aggtatgtcg acagttctat cttggacggc ctacaagacc
     8941 caacgtttgg aaatgtcgat cttgcttcac atgattgtta atgggattgc tttctgtttg
     9001 ttggctcttg tggtgattat gagtcggaca ttaggaattt ctgtttaaaa gtttttatgt
     9061 aggaaccgac ctctttctac tagggaaaga tgaatgcaat cgtgtccatc tttttctttt
     9121 tatggtaaaa tctttttctt tttatggtaa aatagaaaaa taatatgatg aaaatccttg
     9181 agggagtgac cgatatgtca agtaaagcca atcatgcaaa gacagttatt tgcggaatta
     9241 tcaatgtaac cccagactcc ttttcggacg gtggtcaatt ttttgctctt gagcaggcac
     9301 tccagcaggc tcgtaaattg atagcagaag gagccagtat gctcgatatc ggcggagaat
     9361 cgactcggcc gggcagtagc tatgttgaga tagaagagga aatccagcgt gttgttccag
     9421 tgatcaaagc gattcgcaag gaaagtgatg tcctcatctc tattgatact tggaagagtc
     9481 aagtagcaga ggctgctttg gctgcgggtg ccaatctagt taatgatatc actggtctca
     9541 tgggtgatga aaaaatggcc catgtggttg ctaaagctgg agcgaaagtg gtcatcatgt
     9601 ttaacccagt tatggctcga cctcagcatc ctagttcgct tatcttccct cattttggct
     9661 ttggtcaaac ctttacagaa aaagagttag ctgactttga aacattgcca atcgaagact
     9721 tgatggtggc tttctttgaa cgagcactag cgagagcggc agaagctggt attgcaccag
     9781 aaaatatcct gttggatcca ggaattggct ttggtctgac caagaaagaa aatctcctcc
     9841 ttttacggga cctggataaa ctacatcaga agggctatcc aatctttctc ggagtgtcgc
     9901 gcaagcgatt tgtcatcaat atccttgaag aaagtgggtt tgaagtcaat cctgagacag
     9961 agcttggttt ccgaaatcgg gacacggctt cggctcatgt aaccagtatc gctgcgagac
    10021 agggtgtaga agtggtgcgc gtgcatgacg tagctagtca caggatggca gttgaaattg
    10081 cctctgccat tcgtctggct gatgaggcgg aaaatttaga tttaaaacaa tataaataag
    10141 atgaaagaaa ttgaaaacaa tcagtggatt gctaactacc ggacggatca accgcatttt
    10201 ggcttggaac gaatggtgga actgttagtt ttgcgtggca atccccatct caaactcaag
    10261 gtcctccata tcggagggac taacggcaag ggctcgacta ttgctttttt gaaaaagatg
    10321 ctagaaaagc tagggttgag agttggcgtg tttagctcgc cctatctcat tcattacaca
    10381 gaccagatta gcatcaatgg ggaatcgatc tcagaagcga ggctagaagc tctcatggca
    10441 gactatcagt ctttgctgga gggagaagcg gtcgccaatt tacagggcac aaccgagttt
    10501 gagattatca cagccctggc ctatgactac tttgcctcag agcaagtaga tgtggccatc
    10561 atggaagttg gcatgggtgg acttttggat agtaccaatg tctgtcagcc cattttgaca
    10621 ggaattacaa ctattggctt ggatcatgtg gctctacttg gtgacacctt ggaggccata
    10681 gcagagcaga aggcaggtat tatcaaacaa gggatgccct tggtaacagg gcgtattgct
    10741 ccagaagcct tggctgtgat tgaccgcatt gcggaaggga aagatgcacc gagacttgcc
    10801 tacgggacag attatcaggt tcgtcatcaa gaaagtgtgg tgacagggga agtctttgac
    10861 tatacaagtg ctgtcagaca aggtcgcttc cagactagtc tgcttggttt gtaccaaata
    10921 gagaatgctg ggatggccat agctttactt gatacttttt gtcaagaaga tggtcgagag
    10981 ctagcaagca atgactttct tggtcaagcc ttggaagaaa caagttggcc agggcgtttg
    11041 gaaatcgtgt caagagatcc cttgatgatt ttggatggag cccacaatcc ccatgctatc
    11101 aaggccttgt tggtaacctt gcaagaacgt tttgcggatt atcataagga aatcctcttc
    11161 acttgtatca aaaccaaagc cttggaggat atgttggact tgctgggagc catgccagat
    11221 accgagctta ctctaacaca ttttgcggat agtcgggcga cggatgaaag cgtgctgaaa
    11281 gaggcagcta agtctagaaa tctcagctac caagattggc atgattttct agagcagaat
    11341 gtgacagata aaaaagaaga gaaacaaaca gttaggattg tcacaggttc cttgtatttc
    11401 ttgagccaag tgagggtcta tctgatggag aggaagaacg agaatggata cacaaaagat
    11461 tgaagcagct gtaaaaatga ttatcgaggc tgtaggagag gacgctaatc gcgagggttt
    11521 gcaggaaaca cctgctcgtg tagcccgtat gtatcaagag attttttcag gtcttggtca
    11581 aacagcagag gaacatttgt caaaatcctt tgaaattatt gacgataata tggtggtaga
    11641 aaaggatatc tttttccata ccatgtgtga acaccacttc ttgccatttt atggtagagc
    11701 gcacattgcc tacattccag atggtcgtgt ggcaggcttg tctaagctag cccgtacggt
    11761 tgaagtttat tcgaaaaaac cacaaattca agaacgtttg aatatcgaag tggccgatgc
    11821 cttgatggac tatctaggtg ctaaaggagc ctttgttatc attgaggcgg aacatatgtg
    11881 tatgagtatg cgtggtgtta gaaaaccagg cactgcaacc ttgacgacag tagctcgtgg
    11941 tctatttgaa acagataagg acctccgcga ccaagcttat cgtttaatgg ggctataaaa
    12001 agaatccgtt tcaagcggat ttttctagaa aggaatcatt atggatcaac tgcagattaa
    12061 ggatttggaa atgtttgcct atcatggtct ttttcctagt gagaaagaat tggggcagaa
    12121 atttgttgtt tcagccatcc tatcctatga tatgaccaag gcagctacag acttggattt
    12181 aacagcctct gtccattacg gagaattgtg tcagcagtgg acgacttggt ttcaggaaac
    12241 gagtgaagat ttgattgaaa cggtagccta taaactggtg gaacgtacct ttgagtctta
    12301 tcctcttgtc caagaaatga agttggaact gaaaaaacct tgggcaccgg tgcatttgtc
    12361 actagatact tgctcggtaa ccattcatcg ccgcaagcaa cgagccttta tcgccctagg
    12421 aagcaatatg ggagataaac aagtaaactt gaagcaagcc attgacaaac tgcgagctcg
    12481 tggcatccat attctcaaag agtccagtgt cttagcgacg gagccttggg gtggagtgga
    12541 gcaggatagc tttgccaatc aagtggttga ggtggaaacc tggctaccag cacaagactt
    12601 gttagaaacc ttgttagcca ttgagtcaga gctgggacgg gtgagagaag tgcattgggg
    12661 acctcgtttg attgatttgg acttgctctt tgtggaggac cagatccttt atacagacga
    12721 cctcatattg cctcatcctt acatagcgga acgccttttt gtccttgagt ccttacagga
    12781 aattgcgcct cattttatcc atccgatatt aaaacaaccg atccgcaact tgtatgatgc
    12841 tttgaaaaaa tagaaaaact ctagttttca gttacttgca actgaaggct agagttttta
    12901 tactcttcga aaatctcttc aaaccacgtc agcgtcgctt taccgtactc aagtacagct
    12961 tgcggctagc ttcctagttt gctctttgat tttcattgag tattaaaata ggtcattttc
    13021 ttctgggagg aggatagttt ctctaccgtc catgtctaaa accagtactc ttgggggata
    13081 acgagggtcg aaaggatggt taaagtcaaa atcaatggct gtagggaggt gttgacttga
    13141 aaagtggaag gtaatctttc cttggttatt aagcaattga aactcgagtt cttcttccaa
    13201 ttcaaagaca ttttttaaga aatggtcgat gatataccaa aaagagtcaa tgatgtcatc
    13261 aggcaagctg gtaacaatgc caaaactagc agatcgcatg tgggtattgg taaaagccat
    13321 atctctgtcc cctttctttt cccttatcat acagcaaata ggattaaaaa tcaagaaaag
    13381 gtgatttttt gaaaaggatt ttagttacag ggagaaatag ggaaaaaatt cctaaaaatc
    13441 taccgaagtt aataggtaaa ttcccaaatt aacttgatta tataactttc agttactttg
    13501 agaagttacc gaaaaatatt tttcatatct attgactttt aggggtaaaa tttggtatga
    13561 tagtaggcgg tattgtttac cccatttgaa aggccccgga accttccaaa tacttttcga
    13621 tgggaaggaa cacccatcac cgtaaacaaa aatcgaacta tatataggag aaatcatgaa
    13681 caaaacaaca tttatggcta aaccaggcca agttgaacgt aaatggtacg tagttgacgc
    13741 aactgatgta ccacttggac gtctttctgc agtagttgct agcgtacttc gcggaaaaaa
    13801 caaaccaaca tttacaccac acactgatac aggtgacttc gtgattgtta tcaatgctga
    13861 aaaagttaaa ttgactggta aaaaagcaac tgataaaatc tactacactc actcaaacca
    13921 cccaggtgga ttgaaacaaa tctctgcagg tgaacttcgt tctaaaaatg cagtacgttt
    13981 gattgagaaa tcagttaaag gtatgcttcc acacaataca cttggacgcg ctcaaggtat
    14041 gaagttgaaa gtatttgttg gagctgagca cactcacgct gcacaacaac cagaagttct
    14101 tgacatttca ggacttatct aaggaaagga acaataaagt atgtcacaag cacaatatgc
    14161 aggtactgga cgtcgtaaaa acgctgttgc acgcgttcgc cttgttccag gaactggtaa
    14221 aatcactgtt aacaaaaaag atgttgaaga gtacatccca cacgctgacc ttcgtcttgt
    14281 catcaaccaa ccattcgcag ttacttcaac tgtaggttca tacgacgttt tcgttaacgt
    14341 tataggtggt ggatacgctg gtcaatcagg agctatccgt cacggtatcg ctcgtgccct
    14401 tcttcaagta gacccagact tccgcgattc attgaaacgc gcaggacttc ttacacgtga
    14461 ctcacgtaaa gttgaacgta agaaaccagg tcttaagaaa gctcgtaaag catcacaatt
    14521 tagtaaacgt taattcgaaa gaattactat acttatacag agcacctttc ggggtgttct
    14581 ttttttatac tttcttacta aattggtgca attgacacag ttgttgcgac tttagtcgct
    14641 tacaaatgtg gctgcaacct gacatggtca gttgcctcaa aacgttaatc aatacgatta
    14701 tatcaacgtt tcaaagcact caagggttta ccctatgggt gcttttttct atactttcta
    14761 aaaaagtttg ccctaaaatt tgccctaaaa ttaccctact tatttttaag atgttggtag
    14821 gcaacttgtc cagcagataa tggaactatg tttgaagtat taacataagt cttagttgta
    14881 acggtatcgc tatgagttaa tgcttcagaa atggcttcta agctcatttc tgctttttta
    14941 gcaagtgtcg ctcctgtatg tcgtaattta tgcggtgtag cgtgtgtcag ttctttatgt
    15001 cgctttctaa tgcttttcat tttattgttc agatagtcgg catgtaaagg cttgttgatg
    15061 tttccttttg tgtcgatata tgtaaaaaca aattgttctg gattactgag gatgccaaac
    15121 tttgctagtt catatctttg ttgtttttcc caagagataa gaagttgaag taaatcatta
    15181 gaaatagaga aaaataggat agcaaaagct ctatttcagg agaaaatgaa gcaaatattt
    15241 ccataataaa acgcatatta tcaaggttgt tcaacacctg atatgcgctt ttctgatttt
    15301 aaagactgat tgctcagtct ctttttcatt ataattcagt tacaatttaa tcttatttga
    15361 gaaagtgggt gatgctattc tctaataaga ctatgatatt aatttttgat agtacttcca
    15421 gaaattatag gtcccctttc atccccaatt tctattttca agtgtccgta ttatatggcg
    15481 tattcgaaat tcactatatc ttgttaggat ttgggtagaa tcattgataa cagactgttg
    15541 caaatctaat tagctgtatg atttatattt atctattttt ctagtaacca atctataatg
    15601 tttttcttct cgattccatt gtaattggct gttggatgaa tcgtatccat tgttaataga
    15661 tatttaggga attgatcttt aatggcttct agtggtctaa gttctctttc tagtgtttct
    15721 ggagcaagtg ttgtttcact gacctgataa taagcgtagt ggccaagatc agttacaaca
    15781 acaaaatcaa cctcatactt atctaaatta ccaacatata cttgtgaata tctacgtctc
    15841 aattccaaat ataccatatt ttccaagata tgcctaatgt cttctttgtg gtctggtaat
    15901 aagagatgtc gtaaacctaa atcaacggga taatattttt ctaaacgttg caataatgct
    15961 ctacctttta catcaaaacg tggaacggaa taaaaaagta aactatctgt caaagttgtc
    16021 aaataatttt ccaaagtatt atgggatatt gaaacatttt ggctgactag ggtattgcga
    16081 atcttatttg ttgatattaa gctacctgta ctactgagaa gggttcggac aatgcgctca
    16141 ataatagtag gatttggttt tcccaatcta gtgacaatat catttaacag tatggagtta
    16201 tatattcctc tgagatagtc aattttttca tcgtaagatg atgtttgcaa taagtaaggg
    16261 aaagcactaa agagataatt gttaaaaatt tctgttgtat tcagattctc tgtgagagat
    16321 tgacctgata gatattcttc aaatgacaaa ggaagaacct ctatctcaac ataccgacca
    16381 gtcaagtttg ttgctaattg gctactcata aagtaggcgt tagatccagt caaatagagg
    16441 tctacatttg ctaagatgaa tagactatct gctaccagtt caaatttttc aacatattga
    16501 atttcatcta aaaagatata gtatgttttc ttgctaacta attgatcttt tatataagcg
    16561 aataatgttt gaaaatgtcg cagatcatag taactcaaat cttcgaaatt gatgaatata
    16621 atctgatcct cgtctacccc agttgctagt aactcctctt tatagagttg aaaaagcaca
    16681 gatttaccag ctcgtctaac tccactcaca actttgatga ttggtcggtc acgatgtctt
    16741 cttaaaaaat ctaaataatg tggtcttttg atatagttca taatagttac ctcaaagata
    16801 gtataataca aatagatgtt attttcaaat atttagaaat aatatttaat ttgtttgatt
    16861 atttctaagt gtttagaa
//
LOCUS       DAVDFK010000039        16616 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.39, whole genome shotgun sequence.
ACCESSION   DAVDFK010000039 DAVDFK010000000
VERSION     DAVDFK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.39"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..905)
                     /gene="phtA"
                     /locus_tag="VUR04_001649"
     CDS             complement(<1..905)
                     /gene="phtA"
                     /locus_tag="VUR04_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET5341521.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQR"
     gene            complement(1160..2893)
                     /gene="ptsP"
                     /locus_tag="VUR04_001650"
     CDS             complement(1160..2893)
                     /gene="ptsP"
                     /locus_tag="VUR04_001650"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET5341522.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(2899..3162)
                     /locus_tag="VUR04_001651"
     CDS             complement(2899..3162)
                     /locus_tag="VUR04_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET5341523.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            3513..3731
                     /gene="nrdH"
                     /locus_tag="VUR04_001652"
     CDS             3513..3731
                     /gene="nrdH"
                     /locus_tag="VUR04_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET5341524.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            3812..5971
                     /gene="nrdE"
                     /locus_tag="VUR04_001653"
     CDS             3812..5971
                     /gene="nrdE"
                     /locus_tag="VUR04_001653"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET5341525.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            6159..7121
                     /gene="nrdF"
                     /locus_tag="VUR04_001654"
     CDS             6159..7121
                     /gene="nrdF"
                     /locus_tag="VUR04_001654"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET5341526.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            7303..8064
                     /locus_tag="VUR04_001655"
     CDS             7303..8064
                     /locus_tag="VUR04_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5341527.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNISNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(8097..8291)
                     /locus_tag="VUR04_001656"
                     /pseudo
     CDS             complement(8097..8291)
                     /locus_tag="VUR04_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811474.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 domain-containing protein"
     gene            complement(8334..9740)
                     /gene="lacG"
                     /locus_tag="VUR04_001657"
     CDS             complement(8334..9740)
                     /gene="lacG"
                     /locus_tag="VUR04_001657"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET5341528.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(9955..11646)
                     /locus_tag="VUR04_001658"
     CDS             complement(9955..11646)
                     /locus_tag="VUR04_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET5341529.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKVETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(11646..11963)
                     /locus_tag="VUR04_001659"
     CDS             complement(11646..11963)
                     /locus_tag="VUR04_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5341530.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(11999..12835)
                     /locus_tag="VUR04_001660"
     CDS             complement(11999..12835)
                     /locus_tag="VUR04_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5341531.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(13071..14051)
                     /gene="lacD"
                     /locus_tag="VUR04_001661"
     CDS             complement(13071..14051)
                     /gene="lacD"
                     /locus_tag="VUR04_001661"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET5341532.1"
                     /translation="MALTEQKRVCLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSVKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(14053..14982)
                     /locus_tag="VUR04_001662"
     CDS             complement(14053..14982)
                     /locus_tag="VUR04_001662"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET5341533.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            complement(14993..15508)
                     /gene="lacB"
                     /locus_tag="VUR04_001663"
     CDS             complement(14993..15508)
                     /gene="lacB"
                     /locus_tag="VUR04_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET5341534.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(15539..15964)
                     /gene="lacA"
                     /locus_tag="VUR04_001664"
     CDS             complement(15539..15964)
                     /gene="lacA"
                     /locus_tag="VUR04_001664"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET5341535.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(16121..16585)
                     /locus_tag="VUR04_001665"
     CDS             complement(16121..16585)
                     /locus_tag="VUR04_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET5341536.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDRLEDKKNVCILEANQVEELGFEIEVL"
BASE COUNT         4970 a         3450 c         3015 g         5181 t
ORIGIN      
        1 cgttgactca aaggcagttt gtagagctgt ttcaagagac tatcaatgtc attactttga
       61 cttgcttgac tgttagtgtt gctgttgttg cttgtgttag tatttgtagt tcctggattg
      121 cttacagaag gtacccagtt tgttcttgaa gtgttatcgc tattttgtcg gcgataggtt
      181 cttgaatttg acagatttcc ccgaccagat aggaaggctt ctgcagcagc caactcgcta
      241 gctgataact cattcttagg aatgtaatgg taatgatctc catgaggaac gatataagca
      301 tcaccagtat cctctatgat atcagaagca ttaaagatat aaccatcatc tgtagtatag
      361 cgtccttgcg aacgtgccaa ggcaacagca ccatcgtttc ttggagtccc accttcacga
      421 tgttgactat gttcttgttt ttgtcgattg atttcctctt ttgtacggac gttatccgcg
      481 tgggcagcat ccttaaggta aacatagtat tttccatcta ccttgataac atatccaccc
      541 ttgacctcat taacaatatc ctcatctttt agcttatagt ttggatcttt catgagtaat
      601 tcttcactga aaatcgcatc ataaggaacc ttaccattgt aataatgata gtggtcgcca
      661 tgtgaagtga catagccttg gtctgttatc ttgatgacga tttgctcagc attgattcct
      721 tcacgcttgc taacctcatc aggagtcaaa ttctccgttt tttgcgtcgc ttgttttcca
      781 tctatatagg aaacacgatt attttcctta accgttctag cttgatacag tcccaactcg
      841 taagaacaaa cacttaaaat caaagctgcc gcagaaccaa caaggtattt cttattaatt
      901 ttcatcgaaa ctctctttct atttgatatt tctagttgca attcatttct aaattgcaga
      961 aactcctctc tattacttaa ctggttaata gtttactcct aaatctccaa cttgtcaaga
     1021 attttatgaa ccatttaagt attttttgtt ctgaccacta ctttttcaag gttggacttt
     1081 ttataagaaa gattttcttg aaaattcttt ttaaaatatc aaaaaaagtc cctgtaactg
     1141 agttgcaggg acttttcgat taatcaaaat taacgtattc tttttgaagt tcaagaactt
     1201 cttccattgt tgagcattct gtaagggcac ggtttgcgta ctcttccatc ttagctgtgt
     1261 cgagtttctt catcaagctg cgtgtacgaa gtacagatgt tgctgacata gagaactcat
     1321 ccaagcccat tccgacaaga agtggaacag cttgttggtc accagccatc tcaccacaca
     1381 taccagccca tttaccttca gcgtgagctg ctttgatcac attgttaatc aagcgtagga
     1441 ttgatgggtt gtatggttgg taaaggtatg aaacttgttc gttcatacgg tctgctgcca
     1501 ttgtatattg gatcaagtca tttgtaccaa ttgagaagaa gtcaacttct ttagcaaatt
     1561 ggtctgcaag catagccgct gcaggaatct cgatcatgat accaacttga atgttatccg
     1621 caactgcaac accttcagca agaaggtttg ctttttcttc atcaaagact gctttcgctg
     1681 cacggaattc tttcaagagc gcaaccattg ggaacatgat acgcaattga ccgtgaacag
     1741 acgcacgaag aagagcacgg atttgtgtgc ggaacatagc atctccagtc tcagagatag
     1801 agatacgaag agcacggaat ccaaggaatg ggttcatttc gtgaggcata tcgaagtaag
     1861 gaagttcctt atctccaccg atatccattg tacgaacgac aacaggttta ccgttcattc
     1921 cttcaagaac agccttgtat gcttcatact gctcatcttc agttgggaag tcttgagaat
     1981 ccatgtacaa gaactctgta cggtaaagtc caacagcttc tgcaccgttg ttgttaacac
     2041 cttcaacgtc ttttggagta ccaatattgg cagccaactc gaagtgttta ccgtcagcag
     2101 tcactgtttg agcatctttc aaaagtgccc attcagcttt ttgtttcgca taggcttcac
     2161 cagctgcttt aaattctgcc gcttgttcat ctgttgggtt gataatcact tctccagtga
     2221 tcccgttaac agcaaggatg tcaccgtctt taacgatttc agtgatgttg tttgtaccta
     2281 atacagcagc aatttcaagt gtacgtgcca tgatagctga gtggcttgta cgtccaccaa
     2341 tgttggttac aaaagctttt acaaagtttt tgtccaattg agctgtatct gaaggagtca
     2401 agtcatgcgc aatcacaatc acttcttcat tgatagaagc tgggtttggc aattttttac
     2461 caagaaggtt tgccaataca cgttttgtca cgtcgcggat atccgctgcg cgttcttgca
     2521 tgtatgggtt gtcttccatg ccttcaaaga tagtgataaa catatctgta acttctttca
     2581 gacctgcttc tgcattcact ttcttcgcac ggatagtttc cttgatttgg ctgatcattt
     2641 ctgggtcagc aagaaccatt aagtgagcat caaaaacttg agctgcttct tcaccgagcg
     2701 tacctactgc tttctcgcga ataacagaaa gctcgtcttg tgatgcctgt agagcggcat
     2761 caaggcgagc ttcttctgcg tttgtatctt cgactgtaat agtctcaaat gacaaatccg
     2821 gctgaacgag tagatatgct tttgcaactg caacaccgtc agatgctgcg attcctttaa
     2881 gcatttctgt catttccctt atgccaatcc ttctttttcc attgtttctg agattgcagc
     2941 gatagcgtca tctgcatctg caccttcagc tgagatagtt acgtcagcac cttgaccaac
     3001 accaagactc ataacaccca taattgattt aaggttaact gatttacctt tgtactcaag
     3061 agtgatatct gaagcaaatt tgctagcagt ttgtaccaac aatgttgctg gacgtgcgtg
     3121 aatacctgtt tctgccacta cgtggaaatc tttagaagcc atagtttgac tctccttttg
     3181 ttctttcttt ttttgagtta tatgtgataa cccttacaat ttagtattat accatcttct
     3241 aggatttttt tcaagcattt tctggatttt ccttcaattt cctttcagat aacttgctga
     3301 aaatcttcta tcctagataa caaaacacag gatatagttt cttcaaaaac aatttatagg
     3361 ataatcattg ctatttcaca atacaaacac tatatattgt gtttatatat aaaaacaaca
     3421 aaagaacacc actatattta gtttaaatca ttgacaaaat tttattttct gatatactaa
     3481 gatagtatta aattttgaag aggagttaca caatggtaac cgtttattct aaaaacaatt
     3541 gtgtccaatg taaaatgacc aagcgtttct tggacagtaa taatgtctct tatcgtgaaa
     3601 tcaatcttga tgagcaacct gagtacgtcg atcaagttaa agagctcggt tttagcgcag
     3661 ctcctgttat ccaaacacca actgaagtct tttcaggttt ccaaccagga aaactgaaac
     3721 aattagcata atcttagtac atcatccaga agaaactgct tttagggcta acttagaagc
     3781 ctttcttttg taattagata agggaaattt tatgggatta aaacatcttg aagacgtgac
     3841 ttacttccgt cttaataacg aaattaaccg tcctgttaat ggacaaatca tgcttcataa
     3901 agataaggaa gccttggatg ctttctttaa agaaaatgta gttccaaaca ctatggtttt
     3961 tgattcaatc aaagacaaaa tcaattacct cattgaacac aactacatcg aaacagcctt
     4021 tatcaagaaa taccgtccag agttcttgga agaattggct caatttatca aagaccaaaa
     4081 cttccaattc aagtcattca tggcagctta taaattttac aatcaatatg ccttaaagac
     4141 taatgacggt gaatactatc ttgaaaatat ggaagaccgt gtcttcttca acgcccttta
     4201 tttcgctgat gggaatgaag ctgttgcaat cgatattgcc aatgaaatca tccaccaacg
     4261 ctaccaacct gctactcctt ccttcttgaa tgctggacgt gctcgtcgtg gggagttggt
     4321 atcttgtttc ctaatccaag tgacggatga tatgaactct atcggacgtt ctatcaactc
     4381 agctcttcaa ctttcacgta ttggtggtgg tgtgggaatt accctcagca accttcgtga
     4441 agctggtgca cctatcaaag gctatgaagg agctgcttca ggtgtcgttc ctgttatgaa
     4501 gctttttgaa gacagcttct cttactccaa ccaattgggg caacgtcaag gtgccggtgt
     4561 tgtctacctc aacgtctttc acccagatat catcgctttc ctttcaacta agaaagaaaa
     4621 cgctgatgaa aaagtacgtg tcaagactct atcacttggt gttgtagtac ctgataaatt
     4681 ctacgaattg gctcgtaaaa atgaagaaat gtacctcttc agcccttact ctgtagaaaa
     4741 agaatacggt gtgccattca attacatcga cattactgaa aaatacgatg aattggtcgc
     4801 aaatccaaat attcgcaaga caaaaatcaa ggcgcgggat ttggaaactg aaatctctaa
     4861 attgcaacaa gagtctggct atccttatgt agtcaacata gatacggcta accgtgcaaa
     4921 tcctgttgat ggaaagatta tcatgagtaa cttgtgttct gagattcttc aagttcaaga
     4981 accaagcttg atcaacgatg ctcaagaatt ccttcaaatg ggaacagatg tttcatgtaa
     5041 cctgggttca accaacgtgg ttaacatgat gacttcacct gattttggtc gttctatccg
     5101 tgctatggtt cgtgccctta ctttcgttac agatagttca catatcgtag ctgtaccaac
     5161 gattgaccat ggaaatagcc aagcccacac ctttggtctc ggtgccatgg gactgcacag
     5221 ctaccttgcc caacaactca ttgaatatgg ttcacctgag tctgttgaat ttacaagcat
     5281 ctactttatg cttatgaact actggacctt ggtagagtca aacaatattg cgcgtgaacg
     5341 tggtattacc ttccacaact ttgaaaaatc agactatgct aacggaagtt actttgacaa
     5401 gtatgtaact ggtgaatttg ttccaacatc agaccgtgtt aaagaactct tcaaaaatgt
     5461 ttttatccct ggtgttgctg attgggctga acttcgcgac aaggttcaag aagatggtct
     5521 ttaccaccaa aatcgccttg ctgtagcgcc aaatggttct atcagctata tcaacgacgt
     5581 ttctgcttct atccacccga ttacgcaacg tatcgaagaa cgccaagaga agaaaattgg
     5641 taaaatctac taccctgctg ctggcttgtc tacagaaacc attccttact acacttctgc
     5701 ctacgatatg gatatgcgta aagtcatcga tgtttacgct gctgcgactg aacacgtgga
     5761 tcaaggactt tcactcaccc tcttcatgcg cagtgacatt ccaaaaggcc tttacgaatg
     5821 gaagagggaa aataaacaaa cgacacgtga tttgtccatc cttcgtaact atgcctttaa
     5881 caagggaatc aagtctatct actacgtccg tacctttaca gatgacggtg gagaagtcgg
     5941 cgccaaccaa tgtgaaagct gtgtgattta gtttctagca tagaaacatt atttttccct
     6001 aagcagcact gataaaatca aatctactat gtcataacat aatttatgta acattttaaa
     6061 agtcgggctt ccgacttttt gtgcgatact cctatagaat tatggtaaag tagaaataat
     6121 tgtgagttcg caatactaaa cacagaaaga gattttaaat ggaaacttac tacaaagcca
     6181 ttaactggaa tgccatcgaa gatgtcatcg acaaatcaac ttgggaaaaa ctgacggagc
     6241 aattttggct cgatacacgt attcccttat caaacgactt ggatgactgg agaaagctat
     6301 ctaacaaaga gaaagacttg gtcggaaaag tttttggtgg tttaaccctt cttgacacta
     6361 tgcaatctga aactggggtt caagcccttc gcgcagacat ccgtacacca catgaggaag
     6421 ctgttttcaa taacatccaa tttatggaat ctgtccacgc taaatcttac tcatcaatct
     6481 tttctacctt gaatactaag gctgagattg aagaaatttt cgaatggacc aataccaatc
     6541 cttacctaca aaagaaggct gagattgtca acgaaatcta cctaaacggc agcccacttg
     6601 aaaagaaagt tgccagcgtc ttcctcgaaa ccttcctctt ctactctggt ttcttcactc
     6661 ccctctacta tctcggtaac aacaaactag ccaacgttgc agaaatcatt aaattgatta
     6721 ttcgtgacga gtctgttcac ggaacctaca ttggttacaa attccaactt ggtttcaatg
     6781 aattgcctga agaagagcaa gaaaaactca aagaatggat gtacgaccta ctctatactc
     6841 tttatgaaaa tgaagaaggc tacacagaga gtctttatga cggtgttggt tggactgaag
     6901 aggttaaaac cttccttcgc tacaatgcca ataaagctct catgaacatg ggacaagatc
     6961 cacttttccc agattcagct gaagatgtca acccaatcgt tatgaacggt atttcaacag
     7021 gaacttccaa ccatgacttc ttctctcaag tcggaaatgg ttaccttctt ggcgaagttg
     7081 aagccatgca agacgatgac tataactacg gtttagacta attctccatc actctcaatc
     7141 atcaaaaagt aaactagaaa catcaaagtt ataacccaac aaaaatatcg aaagttttga
     7201 aaacaaactt cgatattttt gtttttgttt cattttgttg tttttgtatt tgaatgatga
     7261 gtttgtttat ggtaagatag tagtaggaaa cgaggtgata atatgctcaa acaagaaaaa
     7321 ttaaccaaaa ttttagagat agtaaatagt aaaggaacca taacagttaa acagattatg
     7381 gacgaaatag ccgtttcaga tatgactgca aggcgctatt tacaggaatt agctgataaa
     7441 gatttgctga ttcgtgtgca tggtggagct gaaaaacttc gaactaactc ccttttgact
     7501 aatgagcgat caaatattga aaaacaagcc ctccaaacgg cagaaaaaca agaaatagcc
     7561 cattttgcag gcagtctagt agaagaaaga gaaactattt tcattggacc aggaacaaca
     7621 ttagagtttt ttgcgcgtga gttgcctatt gacaatatcc gcgtcgtaac caacagtcta
     7681 cctgtttttc tgattttaag cgaacgaaaa ttaacagatt tgattttgat aggtggaaat
     7741 tatcgcgata ttacaggtgc ttttgttggc acattgaccc tacaaaatat ctctaatctc
     7801 caattttcta aagctttcgt tagctgtaat ggtattcaaa acggagctct agctactttt
     7861 agcgaggaag agggagaggc tcaacgcatc gctttaaata attctaataa aaaatattta
     7921 ctcgcagatc atagtaaatt caataagttt gatttttata ctttttataa tgtatcaaat
     7981 cttgatacta ttgtttcaga ttctaaacta agtgattcaa tcctttttaa gctatctaaa
     8041 cacattaaag tcatcaagcc ttaataaact gaaagagcct gggtaacaac tcaatttcag
     8101 aagaaaaaaa gtaaatcttc ccacaataaa acgcatagta tcaggtgttt caacacctga
     8161 tactatgcgt ttttctatat caaagacttt ttgcccaatt cctcactcgt caaacacggt
     8221 atttgagagc atttttcgaa atttataata taaacttttt cataaataga ttggataaaa
     8281 tctttgaaca tctttttgac tcactaaaat tctatatcta atgactaatt ctactagtct
     8341 ataatctgag tttccgctac tttcttgtac cagtgagctg atttcttagg ataacgttct
     8401 tgagtttcaa aatctacgta gaagagacca taacgtttct cataaccgtt tgaccatgag
     8461 aagacatcca ttaatgacca aatgaagtaa ccttttacat tagctccatc tgcaatcgca
     8521 tcagacaaga tctccaagtg ttgtttcacg taatcaatac gaccatcatc gtaaacagtg
     8581 ttatcaacga actcatcttt atagccaaga ccattttcag tgatgtagat tttcttatag
     8641 ttaggataat ctttcttcac gcgcatgatt tggtcataca aaccttgagg gtagataatc
     8701 caatcccaat ccgtgcgtgg tacatagtca ggagctacac gacgaccaat acctttgatt
     8761 tggtatttag agcttccttt ttcaccttta ccattatgga taatttcagt ttctccatca
     8821 aaggcttcca tccagtcact catatagtag ttgattccta ggaaatcatt caagtctttt
     8881 gcagcttcta atgctgtaaa atcttcttca cgaagatcca agctaccacc attggcagcc
     8941 aagatagcct ctacccctgc cagagtcttt tcagagtagt gacccagata ggttgcatcc
     9001 aaaataaatt tgttgtgaat aatatcttcc aactcagctg cacgaacatc tgctggattt
     9061 tcatgatcta gaggatattt agtaggcagg gcgtgaacaa caccaatttc ccctttatag
     9121 cctttctctt tgtacaattt taccgcgcgt gcatgagaca ccatcatatt gtggtgtgat
     9181 tgaaagactt tggcaaggtc gtactggata cctggaggga atttcccaac caaatattga
     9241 ccatcaccga ttggtccaat ttcattaaag gttgtccaat agtttacttc tggaaattct
     9301 tcaaaacaga aggcagcgta gtctacaaaa tgttcgatat tttcacggtt taagaagtct
     9361 ccatttgagt ggagagcttc tggcgtgtca aagtgatgaa gagttacaaa aggctcaaca
     9421 tgacgtttgt gacactctgc aaataaatta tgataaaact caacaccttt agcatttact
     9481 tggccgtaac cagtcgggaa aatacgtgac caagcaatag aaattcgaat accattgaca
     9541 ccatactctt ctgctagctt gaggtcaact ggatatcgat tgtaaaaatc actagctggt
     9601 tcggcagtgt accagtagtt atcctcaaga tatttatccc aagcaactgg tccttttcca
     9661 tcagtatgtg tagcaccttc tgcttgataa gcagctgttg cgccaccgaa aataaagtct
     9721 tttggaagtg tttttgtcat ttttttcacc tatttcttga tttaaataaa gtaaaagtga
     9781 gaggagagga gtcagtgagc catgcttctc catctcactt cttgtaccaa gtcactgaat
     9841 tgtgacatga ggaggtaaaa acgatatctt tttaccgacg aattaataag gcgattagga
     9901 aattcgccat agcgatttcc gtaacgatag gagactgttt cacagttcct agccttaatc
     9961 gaattgttct tgtacgaatg ctagggcacc ttttccatca cgagttaatt tgatgtattg
    10021 agcgccttct gttttcgcta gtttaatacc gagcttatct gtttctacct tcatatcttc
    10081 aaagtttgaa gcaacttgag gagcaaggat aaccaaatca aactctggta acatttcacg
    10141 gtgagcacca tagccgcctg ctgctgcttt cacagggaca ttgtattctg ctgctgcctt
    10201 attcaaagca tttgcaagga gtccacttgt acctccacca gcacagagaa cgaggacatt
    10261 tgtttcttca gtgatggtat tttgtgctgc atcgacacct gctttttcaa gaatagcatc
    10321 cgcttttgca gtgttgaagt ttgcagcaac tttttctttc aattcatcat tagacttacc
    10381 tgaacgttct tcttcaagaa tttgttcgtc ataaacttta aggaatggat agtaaatgac
    10441 aacgtcaacc acgattagaa gggcagcaag aatgaatgat agcacttgga agttagttcc
    10501 aagaactaga cctagtggag ctggagttgt ccatggtaga ttagcagtga atgagttcat
    10561 tccaagagtt tcaataaaga atttgaaaat ccatacgttt gcaattggag caaagataaa
    10621 tggaatgaag aagattggat ttaatacaag tggtgcacca aacaagattg gttcatttac
    10681 accgaagaag gtaggaacta ctgaagcacg tccgattgca cggttacgtt ttgattttgt
    10741 taaccacata aacatgaatg gaacaaccag tgtcgcacca gtaccaccca tggtaacgat
    10801 aaacatttgt gtaccagaag taagaatctt gtcagcgtgc ataccttgtt ggagaaggtt
    10861 caagttgact tcggcatttg cataggtaat agctgcgata gcaggttcaa cgatagatgg
    10921 accatgaata ccaacaaacc agaagaaggc aaaggcacca aagataatgg tgatacctag
    10981 ataaccatca gcagcagaga ataatggtgc gaagaattta ccgattgatt ctgccacact
    11041 agaaccaaca aaatgacgag ctagtaaatc aagagcataa agagaaacca ctgatagagt
    11101 gaatggaatc acatctttaa agacttgtga gatatttggt ggaacttcgt caggcatacg
    11161 aatagtgacg ttgttcttaa cacagacctt atagatggct acagtaacga aggcagcaag
    11221 gaaggctgaa agcaaacctt ttgtccccaa gaatccagta gctagaccac tttcgatagg
    11281 atcagctgcc aacatcaaca aaccaacaat tgctgccaac aatgttgaca tatagttgat
    11341 ttgattggtt ttttccatgc tacggtttac tgagtcagtc aatgacttag ctgttgtacc
    11401 agctaccaag agagccagaa tacccataga atagctataa ggtttcatca gaaaggctac
    11461 aacttcatca gaccatttaa agccccatga gtttggtaca aaggcaatca agataaagat
    11521 acttgagaag agaataacag gcatacctgc aatgaaacca tcacgaatag cacgaagata
    11581 gatattacga gatagttttt caaagaaagg ctttcctttc tcgataaatg caattagttt
    11641 attcattatt taactcctct cttgtagagt tcaattaaat gatgcatcaa atcttttaac
    11701 aagatagttg tcattaagtg gtcttggcca tgcatcatgg ttacactata agccaagtcc
    11761 tcacctgaag cttccttagt caatagactt gtttgcgcgt ggtgagcctc tgcaatacag
    11821 ctaccagctt cctctaccag agcgtccgct ttttcaaaat caccagcttc agcagccttc
    11881 aaggcttcca atagttttga acgagcatcg ccagcatagg ctacgatttc aaaacctaac
    11941 aatgttactt cttctctatt catgatagaa ttctccttat atagttttaa ataaattttt
    12001 atgacaataa acgttggata tgtagaacta gataaactcg ttcactttta tacaaatcaa
    12061 gacccgtatg ttgcgtaatc acatcataga tcttggaacc aatctcgaag gcttttggat
    12121 aggattgttt aatatgatct tccatatcca gaagtgattg gttatcatct ctagatctgt
    12181 ctaaataatc caagaaataa ttcaaatgga tcataaagcg atcatagaaa tggttattct
    12241 ttttagttcg ttgaattgca tagtccgtta aaacttcttc aacattcctg agaatttctt
    12301 tcctcttatc aatcgactcc acaagttcca cttcattttc accttcagca ttaatgaaat
    12361 gataagcaat ccgaataatt tcgtcctcag gaaaatgatc tgctagcttc tgacggtaaa
    12421 tttcaaaagc ttcatttgcg atttgaaaag cgacaggata cttagcggaa atatccggca
    12481 gattactatc cttgtacctt ccttgagtta gagcttgata agaacagtaa atatgatctg
    12541 tcaaggttac atagagatac tcttgaatcg gataatgata tttctttgat agcttatcaa
    12601 tgatttcata ggtcactgtg ataaaatcaa gcggaacatc tttgagaaga gccataaagt
    12661 tttctctgga ctcttcggtc ttcatccgaa agattttctc aacctgattt tcagcaatca
    12721 aatccccctt cctttttccg aatgcaatcc ccttaccaat tataatcacc tcttctccct
    12781 tatcatttct gacaagcgag acattgtgat tcattggatt tagaattcga tacatgtcaa
    12841 cctcctttta tatcttaaag gtatatgagt acaaaaaaaa tgaccacaaa tgaactagaa
    12901 aatcagctga tttctaattc acctgtgatc atgcctaata ttacttagta acactcacct
    12961 tgtattaact tgtgatttaa gtatagcaca agtaagttat tttgtaaacc tttacataca
    13021 acttttttta aattttttta gattcatgtt cctaaactag gaggactttc ttacacacgt
    13081 tctttccatg aagtcgctgt tgtttgaaga actttgttga gctcatcaat gttttcaaat
    13141 ccagttgtgc gaagccattc gcgagctgct gtttcaccat ctttgatgta tgcttcaact
    13201 gatccagccc atgttgcacg gccacaaaga actccgttaa agtttgcacc tgattcatga
    13261 gcaaatacaa gagtatcttg gaagagttta gctgatacac cagcactcaa gtagatgtat
    13321 ggcaagttcg ttgcttcatc ttgcgctttg aagaaggctg ctgcttcttc acgtgtataa
    13381 actacttcac cttcagcgaa gccttcaaca tatttaatgt taacaggaac ttcaactttc
    13441 aagacatcaa tgttaaaacg tgggtctgag aagactttca tagcaccgat aactttgtgt
    13501 ggttttactt tcgcatattc tacagaacct gcgtctgcaa ttttttcatc gtaagcaagg
    13561 atttcaagga agaatgggat atcttcagcc acacactcag aaccgatacg ttcgatgtag
    13621 gcttgttttt cttgattgag ttcgtctgag ctatctacat catagtaaag caagaattta
    13681 actgcatctg caccttcttc tttaatacgt tttacagacc aaacatccaa gcagtctggc
    13741 aagcgttttg tgcttgttgt gtcataacct gttttttcat aagcaaggag aagaccagct
    13801 ttttcatcaa gagctttagt tgctggaagt ccatactcag ggtcaagaag catagatgaa
    13861 gcgtatttag tcaattcatc tgctaccaag actttaagtt cttccatttg ggccacagtt
    13921 ggttcttctg tttggtgttg agccatgagg cgtttcaaag caccacgttg gtcaaatgca
    13981 agagctgaga tgataccatt ttcatcagaa agtttttcta agcatacacg tttttgttct
    14041 gttaaagcca ttttatacct cttttactat taattgatca tatagagctt gatagttggc
    14101 catgttgaca tgaccagtca ttttttcttg agcattgagc ataccaagga catttgcctt
    14161 gatgagtaat tctgcatccg attctttgtg aagaagtcct gaagaaattc ctgccacagt
    14221 agagtctcca gatccaacag gatttaccac ctgaattcta ggaatatcta ccttgtagaa
    14281 agtgtcacca tgtttggcaa aagtaccgtt ggcaccaagt gaaacgataa tccattcaat
    14341 ccctgcaaac aaaggttctt gaagtacttc ttttaattca tccaaatcct cagaaacttc
    14401 tcttccaaga agctgagaca attcttcatt atttggtttg atgactgttg gtttatgggg
    14461 tgattcaaga acagcctgaa gtgctgcacc tgagcagtcc aagactacag gcttaccagc
    14521 ttgattagca agttctacca agctcgcata gtaatcaact ggaaggccag ctggcagact
    14581 acctgagatg gccactactt caactgactc caagagtttt ttgaaatgtt ccaaaaagtc
    14641 ttgaccttcc tgttccaata cttcaggacc tttttcaaga acttctgttt ggttgtctcc
    14701 gtggagaata gcgatacagt tacgagtttc tccctgaatt gagaagaaat ctttctttac
    14761 ttgattatcg atatgttcaa ccaaaaactc accaagtttg ccacccacta aaccagtagc
    14821 aagaacagaa tcgccaaatt ctgaaagtac tcgggtaaca ttgagtccct taccaccagc
    14881 cgttttggtt acatccacca cacgattgac agtatcaatc ttcaactcat ccaagggata
    14941 ggaaatatca atggatgggt tcattgtaac tgttaaaatc ataggttacc tcttagtcgt
    15001 ggtattctcc gcgatcccat ttttcaagga attcagtgaa gaagtttgcg tctgtttgtt
    15061 gagcattgtg actttcaagg tgttcaattt tcgcaatcaa ttttttgttt tcttcagatg
    15121 gtttgtattc agcatgaatg aaagcttcga tgatatcaca cataagcaat tcaccagtaa
    15181 tcttaccacc aaaaccgata acgttggcgt tcaattgttc tttagcataa agggctgttg
    15241 tcatatcacg aaccaaggca gaacgaatac ctggaacttt atttacagcg ttgttgatac
    15301 caacaccagt accacagata cataccccga gatcagcttg accactagtt actgcttccc
    15361 ctactttttt accaaagatt gggtagtgag tacgtgtatg gtcataggta ccaaagtcaa
    15421 tgacttcata tccttttgat ttcaaaaatt ctgaaaccgc cattttttca tctgttacga
    15481 tgtggtcaca tccaattgca attctcattt ttaacttacc tttcttacta taatctaatt
    15541 agcccatttt gttcaacatg tcgaccctaa tttggtgacg accaccgtcg tatttaccgt
    15601 taacaaatcc tttagcgata tttttagcca attcatcacc aacaagttgt gcccccatag
    15661 tgatcatacg tgagttgttg tggccacgag tcatataagc tgaacgttcg tcagatactt
    15721 ctgcagcaac cattcctttg atcttagttg caaccataaa tggaccagct ccataagcat
    15781 caatcacgat accaaggttt tgttcttctt tgtttacttc tgcagcaaca gcgagagtca
    15841 catcaacaaa gtcttgacct tcagctgtaa catccacaag gtggaagttt tctttttcta
    15901 agaagtcttt cacaacttct ttcaatctca aacctgcagc atctgcaccg ataacaatag
    15961 acatattgta tactcctttt tattttttct atgctggatt ccagcagtgt attggctgtc
    16021 tttaaaaaac agtcaattag tcctcacaaa cataatatac tactattgtt tgaagaagtc
    16081 aacagtttgt gtttgttttt gttatttatt ttttactttt ttataaaact tctatctcaa
    16141 accctaattc ttcaacctga ttggcttcta agatacaaac attcttctta tcttctaaac
    16201 gatctccttc ttcaaggaat gttgacaagc cagaccatgg ttcaaaggta atgaaaggtc
    16261 ccttgttcaa agttgaccag atgatgaggt ttggaaattc tgcaaaatgc actttcaatc
    16321 ccttatcatg tttaagagaa cgaagggcaa ttgttcgaga ttgcaattca tccaaagtca
    16381 ctgcatctgt gctgaaaaga tcataactaa gatctatttc tttttgtccc tctagccatg
    16441 gacttctatc ttggaaatcc aacatacctg tttctgggaa aggacgtgga acagagcaaa
    16501 tctcttcttt ctcaaactct agataataat cttcatagac ttcatcatca agtagaggac
    16561 aattaaatcc tggatgtcca ccaataaagt aaggcctgac cttgctagtt tcttta
//
LOCUS       DAVDFK010000040        15583 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.40, whole genome shotgun sequence.
ACCESSION   DAVDFK010000040 DAVDFK010000000
VERSION     DAVDFK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.40"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..200
                     /locus_tag="VUR04_001666"
     CDS             <1..200
                     /locus_tag="VUR04_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341537.1"
                     /translation="LKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFK
                     KRIFIALNIKKERTKFVLSQA"
     gene            complement(249..1160)
                     /gene="trxB"
                     /locus_tag="VUR04_001667"
     CDS             complement(249..1160)
                     /gene="trxB"
                     /locus_tag="VUR04_001667"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET5341538.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLSGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(1226..1450)
                     /locus_tag="VUR04_001668"
     CDS             complement(1226..1450)
                     /locus_tag="VUR04_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET5341539.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(1528..2271)
                     /locus_tag="VUR04_001669"
     CDS             complement(1528..2271)
                     /locus_tag="VUR04_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5341540.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(2271..3071)
                     /locus_tag="VUR04_001670"
     CDS             complement(2271..3071)
                     /locus_tag="VUR04_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5341541.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(3229..3585)
                     /locus_tag="VUR04_001671"
     CDS             complement(3229..3585)
                     /locus_tag="VUR04_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET5341542.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(3598..4110)
                     /locus_tag="VUR04_001672"
     CDS             complement(3598..4110)
                     /locus_tag="VUR04_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET5341543.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(4110..4604)
                     /locus_tag="VUR04_001673"
     CDS             complement(4110..4604)
                     /locus_tag="VUR04_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341544.1"
                     /translation="MEIRLAFPNEVDAIMQMMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            4739..5185
                     /locus_tag="VUR04_001674"
     CDS             4739..5185
                     /locus_tag="VUR04_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET5341545.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            5182..5829
                     /locus_tag="VUR04_001675"
     CDS             5182..5829
                     /locus_tag="VUR04_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET5341546.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(5850..6431)
                     /gene="pdxT"
                     /locus_tag="VUR04_001676"
     CDS             complement(5850..6431)
                     /gene="pdxT"
                     /locus_tag="VUR04_001676"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET5341547.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(6432..7307)
                     /gene="pdxS"
                     /locus_tag="VUR04_001677"
     CDS             complement(6432..7307)
                     /gene="pdxS"
                     /locus_tag="VUR04_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET5341548.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(7459..8838)
                     /locus_tag="VUR04_001678"
     CDS             complement(7459..8838)
                     /locus_tag="VUR04_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET5341549.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLNRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            9132..10055
                     /locus_tag="VUR04_001679"
     CDS             9132..10055
                     /locus_tag="VUR04_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET5341550.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVNGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            10115..10720
                     /locus_tag="VUR04_001680"
     CDS             10115..10720
                     /locus_tag="VUR04_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5341551.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            10739..11983
                     /locus_tag="VUR04_001681"
     CDS             10739..11983
                     /locus_tag="VUR04_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5341552.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12100..12357)
                     /locus_tag="VUR04_001682"
     CDS             complement(12100..12357)
                     /locus_tag="VUR04_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET5341553.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(12399..14435)
                     /locus_tag="VUR04_001683"
     CDS             complement(12399..14435)
                     /locus_tag="VUR04_001683"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET5341554.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMVAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEENLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(14647..15564)
                     /gene="glyQ"
                     /locus_tag="VUR04_001684"
     CDS             complement(14647..15564)
                     /gene="glyQ"
                     /locus_tag="VUR04_001684"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET5341555.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
BASE COUNT         4513 a         3549 c         2846 g         4675 t
ORIGIN      
        1 ttctaaagga caaagagaaa atcgtcaacg cccttcaact acactattct aacgccaaac
       61 tggaagcgac caataatctc atcaaactta tcaagcgcaa tgcctttggt tttcggaact
      121 ttgaaaactt caaaaaacgg atttttatcg ctctgaacat caaaaaagaa aggacgaaat
      181 ttgtcctttc tcaagcttag cttttcttca acccactaca gttgacaaag agccaaactt
      241 ttttatgatt aactatgttc tgtaatgaat ttataggctt cttgaccagc gatagctcca
      301 tctccaaccg ctgttgttac ttggcgaagg tctttcaagc gaacatctcc aactgcaaag
      361 ataccgtcga ctgcagtttt catgtggtta tctgtcacaa tccatcctgc ctgatcttgg
      421 atattcaatt ctttaacaaa atcgctaaga gggtccaatc caacatagat aaagacacca
      481 ccgaaggctt gttctgtcac ttgacctgtt ttcacatttt caaatacgac tgattctact
      541 cgattttcac ccttgatttc ccttactaca gaatcccaga taaagctgat tttttcattc
      601 gcaaaggcgc gatcttgtaa aaccttttgg gcacgaagtt ggtcacgacg gtgaacaatg
      661 gtaacagtct tagcaaaacg agtcaagaag agggcttctt caacagctga atctccacca
      721 ccaactacca ataaatcttg gtcacggaag aaagcaccat cacacacagc acagtaagaa
      781 acaccacgac tgttcagttc ttcttctcca ggcactccca aaggacggtg tttagaacca
      841 gttgctacga taactgtacg tgtttcatat gtttggtcat cagtcatcac tttcttaaaa
      901 tcaccatggt cttcgacatt ttcaacataa ccataaatgt gctcaacacc aagattttca
      961 agtggttcaa acatcttttc agccaattca ggtccactaa tattagcgta tcctgggtaa
     1021 ttttcgatat cagatgtatt attcatctga ccacctgaca gaccaccttc aatcaaagct
     1081 acttttagat tgcttcgagc agcatacaag gccgcagtca tccctgcagg tccagcaccg
     1141 ataataatag tatcgtacat atagattcct tctttcttgt tgtaactatc tttattctaa
     1201 ctctttcttg tcaatcacgc aaggattatg ccttgaaaac aagaattaaa ctcataaccg
     1261 caaaggataa tactgggaca accaagactc caatcataat catatcatag agatgggctt
     1321 ggcgagcctt ggctgtctta tcaactcccg acatggctct cagaccaatc caaatcccta
     1381 aaaaaatcag aacaaggatg gtggtcaaga tcaaactctc gaaatataaa gaaaatagtt
     1441 gcagtagcat gatttctctc atttctatct tttttaaaga gtaaactcag ctagtccaac
     1501 taactgagtt ttcctttatc tattatatca aatataagtc cgtttgtaac tagcgaagaa
     1561 ttcttttgtc cgctcttctt taggggtgtg gataatctca tccggagttc cagactcgat
     1621 gattttcccc ttatctaaga agagaatctt atccgcaact tgggctacaa aggacatgtc
     1681 atgactgacc aaaatcatgg tctgacctga cttagcagca tctgcaatag acttttctac
     1741 ttcaccgacc aattctgggt caagggctga agttggttcg tctaagagca aaacatctgg
     1801 tttcatagca agcgcacgcg ctagggcaac ccgttgcttc tgtccacctg ataaatggcg
     1861 aggataatgg ttttcacggt ccgaaagccc aaccttagcc aactcttcct tggcaatctt
     1921 agtcgcttct tggtcagata atttcttgac aacaaccaag ccttctttca cattatcaag
     1981 tgctgttcgg cgttcaaaca aattaaactg ttggaaaacc atagacaact tacggcgtag
     2041 ggcaaggatt tcttcttgag tgattttaga aaaatcaact gaaaaaccat caatctgaat
     2101 agagccactg tcaggtgttt caagataatt gagactgcga agaaaggttg attttccagc
     2161 tcctgaagaa ccaatcaagg ctacaacttc ccctttttga atatccaagt ccagatgatc
     2221 caagacagtc tgtcctgaaa aggatttgct taaattcgaa atcttaatca ttaacgaagg
     2281 tctcctttca catctgtttg cactgtatca ggtgcagaaa tagccatttt tctctcgatg
     2341 aaacgaccga ggctttcaat tccgatattg actacccaat aaacaagggc aacggagatg
     2401 aagcgttcaa aatagcgata atcagctcca cctagaatct gagcttgggc aaagacttcc
     2461 acaacacccg cactaaaagc tagagatgtt cccttggtca aaccgatgag ggaattaatc
     2521 aaggttggag tagctaccac cgctgcatta ggaataatca ctcgtcgata aacttgcgct
     2581 cgggtcatac ccagactgcg tgccgcctca atctcaccag gattaactga gagaatggct
     2641 gcacgaatgg tttcactagc ataagctgcc tcattaaagg caaaggcgac aatcgcaaaa
     2701 gctgcagctg gaatcgcatt gatattgaga ccagttcccc attgctgatt gagggctttc
     2761 aaagccaaag ggattccgta gtaggtcaac atgagttgca ccaaaatcgg tgtccctttt
     2821 aagaaactaa caaagaaggc ctgcaaggga tataaaatct tgacacgatt gatcttcaca
     2881 atggcaaaaa gaagcgccaa aaccaagcca aaaagggcac caccaattgt caacataatt
     2941 gttgttggaa gttgttggac aattctaggg attccatcaa agaccgaacg taggctaaac
     3001 agcttgccat ccggaatcaa ttgcatcaag ttttggtacc aatctgatgc taaaatcgtt
     3061 gtaacattca taaaaacatc ctcttctgat aatgattcat tctaccatgc ttctgccgtc
     3121 aatgaaatta tttgctacgg tcagatacag actttgtcta cctactagtt tatcatactt
     3181 tgaaacaggg aagttatata ttttatctat caaagagata gataaaaact atttcagtcc
     3241 cagttcttca taagattttc gataaccgat ttgcttaaca gttccatttt ctactaaaat
     3301 gggccgtttt aacaacatac cgtcacttgc tagcaactca gccgcttctt ggtttgacaa
     3361 acttcctacc ttatctttta gccctaattc acggtatttg ataccactgg tgttgaaaaa
     3421 ttgcttcaat tcaaatcctg aggtttctag ccaattcaaa atgacttctt ggctaggtgt
     3481 ttcttccacg atatggacgg ctttatagtc cacacctaat tgatttaatt cttgttttgc
     3541 ttttttacaa gttgaacatt tggggtattc gataaattct aacatgtgct tctccttcta
     3601 tttgtttata tctttaaaat ctacgccttc atgctccaag agccaagctt tcttttccac
     3661 tcctgcagca tagcctgtca gacgcttgcc tgctcccaac acacgatgac aaggtactag
     3721 gatagaccaa ggattgcgtc ccactgctcc accaattgct tgagcagaag ccacttgcag
     3781 gtcttgagca atttgtccat aggtcactgt ctgaccataa ggaatgccct gtaaatagtc
     3841 ccaaactctc ttttcaaaat tcgttccaat tggcgccaag agcaagttgg ataaatcctg
     3901 aggcttgcct ttaaagtaat catctaagca agcaataact gggtctaaaa taggatgact
     3961 aacaacttct tctatcgttt catctcctag tcccctctca aaatgcttct gctcctgaac
     4021 ccaaattcca tacaaataat ggtcatcagc tacaagtgat agaataccaa ttggtgagga
     4081 gtagaggatt tttacatact tcttttgcat tatttcttta atttttgata ggccaagcgt
     4141 tcgccatcta ctggcacctt accgacttgt ttaaaaccaa gtttttcaaa aatatgttgc
     4201 ataaccttgt tttcagcatg cgtatctgat cgaaaatcaa gataatcaaa accttcaatc
     4261 aagccctcta agaaggtttg agcaactcct tttccctgca catctgctgc cacagcaata
     4321 cggtgaaaga ctagatactc tgactctcca gcttgccagt ttccctcata aatagcttca
     4381 taggcctcct ctggactctt ggtcacagca gcataggcta gcagttctcc ctcttccaag
     4441 gctacgtagg cttgccctga gatgatatca tcgataataa catctgcatt tggatagcca
     4501 ttttgccact ggtcactacc agcatctgct aaacattttt tggcatcctc catcatctgc
     4561 atgatggcat ctacttcatt tggaaaagct aaacgaattt ccatcttttt tcctcatttc
     4621 tgactagttt ctcccatcat agcataattt aagtatttct acaagcagtt aaaacttgac
     4681 tttgtgtttt tgttatttta taatctagtt atcaaaacta tataaaaagg agttgaaaat
     4741 gaaaactacc ttttcctacc caaaatgggc agaaattcca aacattgacc tctatctgga
     4801 ccaggttttg ctctatgtca atcaggtctg cgcccctatc tctcctaata aagacaaggg
     4861 cctaacagca tctatggtca acaattatgt gaaaaatggt tacctgacaa agcctgacaa
     4921 aaaaaaatac caacgccaac agattgcccg tttgattgct atcacaaccc tcaagtctgt
     4981 attttctatt caagaaatag cccagacact taatactcta caaactcaag caagttcaga
     5041 ccaactctac gatgcttttg tggactacat gaaccaagga attgacccag ctaaccctat
     5101 tatccaaacc agctgccaaa ccgttaaact ctatcatcaa actctagact taatcgatca
     5161 tactcaagag gaggtaatcc aatgaacact agtcttaaac tcagcaaaca actcagtttt
     5221 ggagaggaga ttgctaatag cgtgacccat gctgtgggtg cagtcatcat gcttatcttg
     5281 ctgcctattt catccatcta tagttatgaa gcacacggat ttttatcctc tatcggcgtt
     5341 tccattttcg tcatcagtct ctttctcatg ttcctatcat ccaccattta tcactctatg
     5401 gcctatggtt cgacccacaa atatgttttg cgaatcattg accattctat gatttacgtt
     5461 gccattgccg gctcatacac gcccgttgtc ttgaccttga tgaataactg gtttggctat
     5521 ctgattattg tcatccaatg gggaacgacc atctttggta ttctctataa aatctttgct
     5581 aaaaaggtca atgagaaatt tagccttgct ctttacctga ttatgggctg gttggttctg
     5641 gctatcattc ctgccattat cagtcaaacg acacccgttt tctggagtct catggtaact
     5701 ggcggactct gttatacagt tggagctgga ttttatgcca agaaaaaacc ttatttccac
     5761 atgatttggc atctctttat cctagctgcg tccgcacttc aatacatcgc tattgtttat
     5821 tacatgtaaa aaagttgaga aattcaatct caactttttt ctttacacat attgataaag
     5881 tactggtgca agcgcacatc atcagtcaat tctggatgaa aagaacttac caacatattt
     5941 ttttcttggg ctgcaacaat ttgattgttc actgttgcta gaatttctac accctcacca
     6001 acactactga taatcggacc acggataaag gtcattggaa tcttgccaac tcccttacat
     6061 tctgcttccg tgtagaaact tcctaattgg cgcccataag cattacgctc gaccaccata
     6121 tccatagttc ctagatgact ctctttctga gaagtgattt ccttagccag caaaattaag
     6181 cccgcacagg tcccaaacac tggtaagcca gatagaatgg cttctcggat gggaagtagc
     6241 atgttctggt cacgtaagag cttgcccatg gttgtagact caccaccagg caaaatcaaa
     6301 cccgacaagt cactctgatc ttgctgaaaa tcatctagat ttctgagttc tacactctcg
     6361 acacctaatt gatctagcac ttttgcatgt tctgcaaagg ccccttgcaa ggccaatatt
     6421 ccgattttca tctattttcc tcgttcagcc atgagaattt ggatttcatt ttcattaata
     6481 ccaaccatgg cttctcctaa atcttcagag atttgagcta ggatttgagg attacggaag
     6541 ttagtcacag ccttaacaat ggcactcgct cgtttaacag gatctcctga cttgaaaata
     6601 cctgaaccga caaagacccc ctctgcccct aattgcatca ttaacgcagc atctgctggc
     6661 gttgcaacac ctccagcagc gaaatttaca actggcaatt ttccatgttc atgaacatat
     6721 tggaccaatt ctacagggac ttgcaaatcc ttggcagcaa cataaagctc gtcctcacgt
     6781 aagttttgaa tgcggcgaat ttcctgattc atcatacgca tatgacgaac agcttggacg
     6841 atatcccctg tccctggttc tcctttggta cgaatcatgg aagcaccttc agcgatacga
     6901 cgcaaggctt cacccaaatc cttagcacca cagacaaaag gaacttggaa ttctttcttg
     6961 tccacatgga aacggtcatc agctggagat agaacttcac tctcgtcgat ataatcaatt
     7021 tcaatagcct ctaaaatctg agcttcaaca aaatgcccga ttctgacctt agccattact
     7081 ggaatactaa ccgcttcttg gatttcctta atcatctttg ggtcgctcat gcgggaaact
     7141 cctccagctg cacgaatatc agccggaatt cgttccaagg ccatcacagc tgccgcacca
     7201 gcagcttctg cgatacgagc ctgttcagga ttctgcacat ccataataac accacccttg
     7261 agcatctgtg ccaagttttt atttagttca taacgatttt cagtcatttg ttttatcctc
     7321 atcatttgta ttggtagcta ccttttcatt ttaagtcaga acagaatgaa gcacaagata
     7381 aaaaaactat aattgtatgg ggacagattg gctaaaaact atctgacctt aacttaaggc
     7441 cagatagctc attcattttt atttttcagc cgtaagggca gccattgtga tgtagttgta
     7501 tggtttattg aagtgtggca agaagaagag gtctgtcaat gccaatttat caattgtcac
     7561 atgctcttgg atagcaagtg agaacatgtg gattcccatg ctaattgcaa tatcatgtga
     7621 aaccatttgg gcaccaagaa tttcacggct atctttgtca aagacaatct taattgctac
     7681 ttcatggttg tcatgtttca tgaattctgg tttttgaaga tcgttaaagc ctgtttcagt
     7741 tgcgttgtaa ccagcagctt tcgctttttc aagagtcaaa ccagttgaaa ccatgtgaag
     7801 accgtagatt gagataccat ttgaaccttg aacaccgatt ccttccaatt catgtccaca
     7861 agcgttgtag gcaccaacga taccagtgcg aacagcattt gaagcaagag cgatatagct
     7921 tgtatcttta cgagcattgt cataaacagt cgcacaatca ccaacagcgt aaacgcctgg
     7981 gatagatgtt tcttgtttct tgtctacaag gaaggcaccg ttgcggaaga gttcaatttt
     8041 accatcagca agggctgtgt ttggacggaa accaactgca aggataacca tatccacgtc
     8101 aaagctttct ttgtcagtaa tcaagcgttc aactttaccg tcaccttcga ttgctttaac
     8161 agtttgacct agagccaagc ggatgttgtg atcttccaag ttcttcgcca tcatttgtgt
     8221 gaagtctttg tcatagtaac cgttcaagac agtatcaacg atatcaacaa ggacaacttc
     8281 ttttccaaga cgttcaaagg cctcagcaag ctcaacaccg atgtaaccac caccaacaac
     8341 ggcgatacga ttgaggtgtt ggctcttgtc agaaagttta ttgataactt cttcagcatt
     8401 ttggtacaat ttcacgaatt gtacgttttc aagagttgct ttaaattcgc ggtttccttt
     8461 aacaatttca acaccttcga ttggtggcaa gattggtgta gaacctgtag cgaaaatcaa
     8521 tttctcgtat gattctttgt gttcttttcc ttcaacttct gctgtaacca ctttgttatc
     8581 atagtcgatt gaaagaactg gtgaattcat ataaacctta gcacctttag cttctaattt
     8641 gtctttatca gaatagaaca agccttcagc accatcaatt tgttcaccaa tccaaagagc
     8701 cattccacat cctaggaaag agatgttaga gttttggtca aatacaacaa tttcgttctc
     8761 atttccaaaa ttatccaaca tggtattgat acatgctgta ccagcgtggt tagcaccgac
     8821 tacaacgatt ttactcataa aaatttcctg ccttcattct aaatttacct tactagtata
     8881 ccatttaccg ttagcgttta caaggggggt actattattt cagcattttt tatcaaaaat
     8941 aattccccat ttatcctgtt ttcaagcctc atgaatttta tgagcatatt tcttgacttt
     9001 ttccaaattt tgtttgtgaa aattctaact ttatggtatt ctaataacat gaaaataaaa
     9061 tgtaagggct tcaatttaga taattatttt atattacaac ttattttcta taagagaaag
     9121 gagttggtag cttgactctt cgttcacatt ctgaacggct aatggggact actatcacta
     9181 tttcattagt ggatgagcaa gccgatatct ttctccaaaa atcctttgac ttgctcaaag
     9241 agcttgaata ccgcttcaac gccaatagtc aagaatctga gttgatggaa atcaattatc
     9301 aagcaggaat atcccccgtc acggttcatc cagacctgtt tgagctgatt tcacttgggt
     9361 tagagcatag cctagcgctc tctagccacc tcaatatcag cattggtccc ttaattcaaa
     9421 cctggcgtat cggtttttca gatgccaagg tcgcccagcc tcaagaaatt gaatcggtgc
     9481 tgcctctaat caatcctcat ggtatcgagt tagattcttc tacttctact gtgtttttaa
     9541 aacagaaagg aatgaagatc gatctaggtt gtttagccaa aggatacagt gcggataagg
     9601 ttgcccaatt tcttaggaaa gagggggtga cttctgcctt gatcaatctg ggagggaata
     9661 tcctgaccat tggaaaaaat caggcaagag gggataaccc atggcaaatc gggattcaag
     9721 acccagccaa tcctagggga aatcatttaa tgaccatccc tgttgtcaat aaatctgtcg
     9781 tgacttcagg catttatgaa cgtcacctga ccgtcaatgg acaagattac catcacattt
     9841 ttgacagtca aacaggatat cctgttgaaa cggaactagc gagtctaaca atcatctctg
     9901 ataaatcagt cgatggcgaa atctggacga ctcgactctt tggagaaaga cctgcttcta
     9961 tcctctggca agtcgaaagt ttggagggca tcgaagtcat cctcatcgat aaagaaggcc
    10021 acctaagctg ttcttcagga attcctactc tatagagaca actgtttcaa tggaatttta
    10081 aaattgtatt atgtaaaaag agaaaggaaa tctcatgtta aaacttattg ctattgttgg
    10141 aacaaattca aaacgttcta caaaccgtca attgcttcaa tacatgcaaa aacactttgc
    10201 tgacaaagct gaaattgaac ttgttgaaat caaggccatt cctgtcttca acaaaccagc
    10261 tgacaagcaa gtacctgctg aaatattgga aattgctgct aaaatcgaag aggcagatgg
    10321 cgttattatc ggtactcctg agtatgatca ctctattcca gctgttttga tgagcgctct
    10381 tgcttggttg tcttatggta tttacccact tttgaacaaa ccaatcatga ttacaggtgc
    10441 ttcttacggt acgcttggtt catctcgtgc ccaattgcaa cttcgtcaaa tcttgaatgc
    10501 tcctgaaatc aaggcaaatg ttcttccaga tgaattcttg ctctcacact ctcttcaagc
    10561 atttaaccca agtggcgact tggttgacct tgatgttatc aagaaattgg atgccatctt
    10621 tgatgacttc cgtatctttg taaaaatcac agaaaaatta cgtaatgcac aagaattact
    10681 tcgcaaagat gctgaagact ttgactggga aaatttgtaa gataggagac caaaaagaat
    10741 gaaatttgtt ggacttgttg gatcaaacta cgatcaatca tataaccgta agctcttgga
    10801 atttatccgt cgctacttca aactcaaatt tgaattagaa gttcttgaaa ttgacgaagt
    10861 tccaatgttt aaccaagatg aaaaatggga tgaaagtttc caattacgtt atttatataa
    10921 caaaattact cgtgcagatg gtgttatcat tgctactcct gagcataacc acactatctc
    10981 agcttcactc aaatctgtac ttgaatggct ttcatacgaa gttcatccat ttgaaaacaa
    11041 gcctgttatg attgtgggtg catcatacta tgaccaagga acatcacgtg ctcaagttca
    11101 ccttcgtaaa atccttgatg ctccaggtgt taatgcctac acgcttccag gtaacgaatt
    11161 ccttcttggt aaagctaagg aagcttttga taacaacgga aatatcacca acgaaggcac
    11221 tgttaaattc cttgaaactt gcttagataa ctttgttaaa tacgtaggag tcgtttcgaa
    11281 attgaaaaaa ccaaaaccaa tcgaatcaga agacttggat tgtggaaaac caatcgctac
    11341 aaccatcaca gaagttgacc ctgacgatcc agaatgggta gaaaaagttg cagcaatcac
    11401 tggtgctgtt tctggtgata cctatgtcaa attggaccac ggtatcctaa cagttaacca
    11461 aattgatatg ttcttgaaag ctatgccatt tgaattgaca tacgctgacg acaacaacca
    11521 attcctctac tacaacaacg ctcaccaaga tccagacact atgttcgcta aacgtgtacc
    11581 acctcaatca ggtagccgta tgtcgactgt tcatggttct cttccaccag cacgtatgaa
    11641 gaacgtagag tgggttatcg gaacacttcg caacggaaac caagaatacg tccgtacgat
    11701 cgttccaggt tctcctgcag gtgttatcaa cactcacaac taccaagcaa tgtactatcc
    11761 tgatggatca tacgctggta tcaatgaaat cgtctttaac ttccaaccat ggcttgactg
    11821 gtacctaaaa gagactggtc aacgtttggt gggtggtagc ggaccatttg ctcctgctgc
    11881 cggaggtcat ggagacgccg atgctacttc tggcgcttct gattcagggg atgctggagg
    11941 ccacggtggt gacgcagacg ctacagccgg tgcaagttac taatgatagt ttttaggaac
    12001 cattatggtt ccttttttag cgaaaaaaga ctagcaaaca caaactgcta gtctctttgt
    12061 tatcgtttca tctatctttg ttaaaagaaa gagtacatat tatgaatttg ggtcatcaag
    12121 actacggcca tgtaatcctt tttcacgttg tacttggcgt agtttttctg gtgtaacatc
    12181 gtttccttct tcgtccacaa ttttgattcc ttcaatgtgg tgacgaacag cgcggcgata
    12241 accttcgatg tactcctcac gtagtttggc ttgttccact ttttcttctg gtgttaagcc
    12301 ttctgttttt ttctttttag caagctcatt gatacgagca atttttttcg gatccatttc
    12361 ttctcctctg taataagata aagcccgttt atcaaatttt atttagtgtt aatttggtta
    12421 aaacaagcaa acttagctgc tttcttggtt agttgtgaca agattgccaa acgattttga
    12481 cggacagcct gatcttcagc cattaccata gtattttcaa agaaagcatc aatgactggg
    12541 ctaagcgcaa agagttgttt caattgctga cttgcaggtc ctgataaaac gagtgtttct
    12601 actgcttctg ccaaagcttt ttcttggtca ttctcaaata gtgctgaatc aaccgtagca
    12661 accccttctg ccttctcagc caggttaaag gcacgagaaa gtgattcaac agatggttta
    12721 aaatcttctt ccttgcttac ttctacgaga gcacttgctg cttccaacat atctgccaca
    12781 acaaagtttg aacctgcaag aactgcttcc ttgatatctt ttggagtaga gcccatcatc
    12841 ttatcaacac gagccttgat aaagtccata acctctgctt tattttcata agtcaaactg
    12901 tcaaatttca atgcataaag gctatcaatc agctcatcca tagcaatgtg ccaaccaaag
    12961 gcatccaaga tacgaaccac accttgagtt gcacgacgaa gggcataagg gtcattagaa
    13021 cctgatggaa tcaatcctac tgagaagaaa ctcaaaatcg tatccaattt gtctgcaatg
    13081 gctagaactg caccgacctt gctctctgga agttctcctt cagctgatgt aggcatgtag
    13141 tgttcacgaa tagcagctgc caccgctgga gtttcaccag caagaagggt gtatttttca
    13201 cccataattc cttggagttc gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg
    13261 taaatggctg ctgcacgagc aaggtcaact gtttcatcca ctgacaaacc agctttttct
    13321 gccaaaagta cagtgatttg acccgtacga atcatgtgtt cacgaaggga accaatcttc
    13381 tcatggaagg tgacattgtt taatttttca acaagatctg aaatcaccaa tttttggtct
    13441 tcacgccaga agaattctcc gtcttccaag cgggctacca agactttttc atttcctttg
    13501 atgacatttt tcaaacgctc tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt
    13561 tttccatctt gatcacgaac aacaaagtaa cgctggtgtt ccttcataga agtcaccaag
    13621 acttcttctg gaacttcaag gtatttagca tcaaaacttc ccatgaaggc agttgggtat
    13681 tcaaccaaat tcaagacttc attcagcaaa tccgcatcaa tttcgatacg tacaccatgt
    13741 tttgcctcaa ttttcttgat ttggtcaaca atcatttgct cacgttcaca tggatctgcg
    13801 attacaaact gcttacgaag gttttcttca tagctcaatg ctgactgaat tttggtttct
    13861 ttccccaaga aacgatggcc acggctcaca cgacttccct tgatatcaag gaaatccaag
    13921 tcaaactctt gctcatccaa gagaacagtt aaagtgtgaa cagggcggat gtattcaaag
    13981 ctatttcccg cccagtgcat gctgacaggg aaagtcagtg acttcaagac atccacaatg
    14041 cctggaacaa tggcttcaac tgcttgacca atttcttcct tagtgacata gacatattct
    14101 tcacccttga tttcacggaa ttcgatatct tcaacagtca agccttttcc acggacaaat
    14161 ccttgagctg ctttggtgaa gtttccatca ctatccaagg caattttctt tgctggtccc
    14221 ttgaaatctt ctgtcaaatc agactgtttg tctgataaac cagtcacacg aacagccaaa
    14281 cgacgtggtg ttgagaaggt ttgaatggct tcaaaagaca ggcggttttc cttgaggaag
    14341 gctaccattt tttcgcctag ttgtttttca cttggtgtga caacataggc tggtaattct
    14401 tcaagaccga gttctactaa taagtttttt gtcatgtttt ttctccgaaa agtatctttt
    14461 tattttccag tttgccttat gtgattggca cgcaagcaac caacttcgtt gtttcattgc
    14521 taaaattgga gccaaaagtc tccaattttg cctagtatcc ttagtttcac taaggatacc
    14581 ttcatcactg cggcaactgg ctcagggctc actctgttcg cccattttcg taatttgtca
    14641 ctctctttat tctgcgtctt ctgctaggag tttagctctt gtttcttcat ccaaaagtgg
    14701 gtagcctagg cgtttgcgtt ctgcgacaaa ggttttggct acgacacggg ccaagttacg
    14761 gatacgagcg atatagcctg cacgctctgt tacagatacg gcaccacgcg cgtcaagcag
    14821 attaaaggta tgtgaacatt tgagaacata gtcataggca gggtgtacca agccttcttc
    14881 taatgcacga ccagcttctt tttcaaactt atcaaagttt tcaagcaaca tttcttggtc
    14941 cgaaatttca aatgaatatt ttgagtgctc atactcaggc tggataaaga tttctccgta
    15001 ttttacacca tcagcccact cgatatcata gacagagtct acttcttgaa tgtaagaagc
    15061 caagcgctcc aaaccatagg taacttccgc agtcacaggg ccagttgcca atccaccgac
    15121 ttgttggaaa taagtgaact gagtgatttc cattccgtca agccaaactt cccaaccaag
    15181 accagctgaa ccagttgatg ggttttccca gttgtcctca acaaaacgaa tatcgtgctc
    15241 caaaggattg attcccaatt tttccaaaga ctcaaggtaa agttcttgga tatttgatgg
    15301 agaaggcttc atgaccacct ggaattggtg gtgttggtag agacggttag ggttttcccc
    15361 ataacgaccg tcagcaggac gacgtgatgg ctctacataa gctgcattcc atggctcagg
    15421 tccgatagca cgaaggaaag tgtaaggact cattgttccc gcaccttttt cattatcata
    15481 agcctgcata agcatacaac cttggtcatt ccaaaattgt tgcaaagtaa ggatgatttc
    15541 ctggaaagtc aatttcttag acattgttta ctccttttta tat
//
LOCUS       DAVDFK010000041        15452 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.41, whole genome shotgun sequence.
ACCESSION   DAVDFK010000041 DAVDFK010000000
VERSION     DAVDFK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.41"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(99..3881)
                     /gene="spuA"
                     /locus_tag="VUR04_001685"
     CDS             complement(99..3881)
                     /gene="spuA"
                     /locus_tag="VUR04_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET5341556.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSNDAHKVAKAAFVDPAKLGPQDLTYGKIHNFKTRE
                     DAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVLSYYFV
                     NELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLINEIHK
                     RGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMTKRLLV
                     DSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYAGDENM
                     PTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKNLIAQP
                     TNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNLMVLTA
                     QGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFIHDSYD
                     SSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDRVHLIT
                     VPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEVLADEN
                     QAGTVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSKPEHQN
                     EASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVR
                     KESVENSSKENISATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            4298..4711
                     /gene="rpsL"
                     /locus_tag="VUR04_001686"
     CDS             4298..4711
                     /gene="rpsL"
                     /locus_tag="VUR04_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET5341557.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            4731..5201
                     /gene="rpsG"
                     /locus_tag="VUR04_001687"
     CDS             4731..5201
                     /gene="rpsG"
                     /locus_tag="VUR04_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET5341558.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            5626..7707
                     /gene="fusA"
                     /locus_tag="VUR04_001688"
     CDS             5626..7707
                     /gene="fusA"
                     /locus_tag="VUR04_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET5341559.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            7811..12202
                     /locus_tag="VUR04_001689"
     CDS             7811..12202
                     /locus_tag="VUR04_001689"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET5341560.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSVFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            12304..12567
                     /locus_tag="VUR04_001690"
     CDS             12304..12567
                     /locus_tag="VUR04_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET5341561.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            12560..12838
                     /locus_tag="VUR04_001691"
     CDS             12560..12838
                     /locus_tag="VUR04_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET5341562.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            12859..13011
                     /locus_tag="VUR04_001692"
     CDS             12859..13011
                     /locus_tag="VUR04_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341563.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            13033..14274
                     /locus_tag="VUR04_001693"
     CDS             13033..14274
                     /locus_tag="VUR04_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET5341564.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLYAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NATSDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            14284..14514
                     /locus_tag="VUR04_001694"
     CDS             14284..14514
                     /locus_tag="VUR04_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET5341565.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            14737..>15452
                     /locus_tag="VUR04_001695"
     CDS             14737..>15452
                     /locus_tag="VUR04_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5341566.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILLAN"
BASE COUNT         4342 a         2956 c         3669 g         4485 t
ORIGIN      
        1 aaaaaatcct aatcaagttt attaggacaa caaatattgt acgaaaatta atcccccgag
       61 ctataatgct tgggggattt ttctatagga gggctagctt agttctcttt tttatttttt
      121 agtaagaaac cgagaccaag gagcgcaagg aggctgattc ctgcaaatag gagtttgttt
      181 tcgtttttga ttcctgtatt tggaagttca gcttgtctat ctggggttgc agatatattt
      241 tccttgctag agttttctac cgattctttt cgaaccgctt cttttacaga tgatgcttgt
      301 gcttcttgtg ctggttgttc agcttgtgaa tcagctgtag cttggctagg tttattttcc
      361 gcatcagcta ctttggcatc tggtttagta gaatcaggtc tagcttctgg agctgggtct
      421 tgatgtgcag ggtgagaagc ttcattttga tgttcaggct tggaaggggt tgagtctggt
      481 ttctcttctg cagttgactc atggctagtt ccattttgag agactcgaag aacagtagct
      541 gtaagggcat tcaattttaa gcctttttca gtccattcaa gtcctttcgg gttggcaatt
      601 ccgactgttc cagcttggtt ttcatctgcc aaaacttccg catttcttag atgtgcaaag
      661 gcagttccca aattaaattc gcgagctttt tcatccgcat tgacaaagac tgcgtagata
      721 tcgccgtttg gagcagtgat ttggtagcca atcactacat cctctttttc cacaccattt
      781 tggcctggga cagtgatgag gtggacacgg tctttgatat cttgaagact cttaagtcgg
      841 aaggcatctg tagattgacg aagggcaatc aaacctttca tatagtcacg gctcttgaca
      901 ttttcaggat aagctttacc atctgtagcc ttagtccagt caaacttgtt gactgcatcg
      961 ctagaatcgt aagaatcatg gatgaagtaa ggatagtcaa atgggttgcc gtccttatca
     1021 cgcaacaagt gagatttgtt tggaacctta tcctctgcta ctggagtctt gtaggctggg
     1081 tcacggaatt gtttagtacg tccatattcc tgaccggagt ggataaatgg agttccttga
     1141 gctgtcaaga ccatgagatt tccaagtcgt aaacgacggt ggatttcagc atagttctca
     1201 gccttgcttg ggtctttttt gatagactgg gcaatgatgt caaagagggt caagttatca
     1261 tgggctgcga tgtattggat gacatctcca gggctgtcag cttcaaagtt agttggttga
     1321 gcaatgagat ttttaaagat ggtgttgaca tcacgcttgc cacctgtgat aaaggcaggt
     1381 tgaccttcgt ttggataacc agatttgagg ttgttacgga tgtcatctga aaagacagcg
     1441 acagtatcgg tatgtttcat ccaatcttgg tcagcagctt tagtaggcat gttttcatca
     1501 ccggcatagg ttctccaacc ttcaccaagc atgatgaggt ttggattgag ggcgcgtgca
     1561 gccttgtaag cttcttcgat agaagcggcg tcatggtctc ccatcatatc gaagcggaag
     1621 ccatccactt tgtaggtatc aactaggtat ttgatagagt caactaggag gcgtttggtc
     1681 atatggtggg ttgtccccaa gcgtccacca ccaaagctag ttcgaggtgt gccatcggca
     1741 tccataaagt ggtagtagtt tggctctagg tcttcaaaga tatcgacttt ggctgtgtgg
     1801 ttataaacga catctaggat agctcccata ccacgtttgt ggatttcgtt gatgaggttt
     1861 ttaaattctg cgattcgttt ttctggattc ttaggatcgc ttgagtacat accagtcaag
     1921 gagaagtagt tttgagggtc atatccccag ttgtagttgc tgttgcttga agcatagtca
     1981 gacaagcgtt catggttttt caattcattg acaaagtagt aagacaagac tggaaggagc
     2041 tggatatggg ttacacccaa gtctttgaga tagtctagtt tttcaatgaa ggcttcaaaa
     2101 gtcccaaatg gtttggtcaa gtcttttgca atggcaggat ctgaagtgaa gtcacgcaca
     2161 tgagcttcgt agataacggc gtcttcacga gtcttgaaat tgtgaatctt accataagtc
     2221 aagtcttgag gtccgagttt agctggatct acaaaggcgg ctttagccac tttatgggca
     2281 tcgttgctat tccaagcagc aagagattta gcgtaaggat cgagtgcaag aacagtttta
     2341 ccttgacgct cgatttggta ttgataatag tagccagtga aatctgtgat tccgagtttg
     2401 tttgtgctgt ctagagtttg tttccaagtt cctctttccc ctttttcgag agcgacagtt
     2461 ccaactactt tgtcagggtc attcttgtcg tagacaacaa cagaaacctt atcagcactt
     2521 ggtgaccaaa gggtcaaatc aacttgtttt ccttcttctt ttaggtcagc tcccagtttg
     2581 ccatcatagc tgtatgtctc atctttcagg cgccagcttg ttttggtagt gaattggtcg
     2641 gaattgtagc taacagtata aggatgtttt gtgtcagaga aatctccgct gtaggtcact
     2701 ttcttaccag cttcatcgat tgcaacatcg gtaatagtta ccttgtttcc taggtgatta
     2761 gtgatgttgg agtgtttgag gatatcttct tttttagcac cgacaagtgt tgaaaagcta
     2821 ctttcaatgc tagaagtgcc tacgtgttgg gctcctgtca tacggatatc atggacatag
     2881 tatggatttg tgtaaatcga ttcatcatcg tcttttagga aaatttggct atgatttttc
     2941 aaatctgtga acttataatt ttctttacgg attttcacgt cgtctccttg tttgctctca
     3001 tctagtaata aaaatccaaa ttctcttgcg gcttcattaa gaggaatgtc gatatagcgg
     3061 ccatatttgc ctgtagccgt aaagtctgtt ccgtcaggcc attgagcgct acttggattt
     3121 tttacatctc cccagtacca gagagatttc ttgtcatagt tgccatctgt gcggtagtag
     3181 ttgacgcgaa cagttcctgc aggctgtggc tcgtaagaga aaaccttgta atcttggtct
     3241 aaccaagcct cgttcatttt tggaactagt ttttctacag atttatcgcc ggttagattt
     3301 tttccagctg tattgttgat gaggaagcta attttcttgg cttgttctcc ctttaatttg
     3361 acatctaggt aatagccgta gtcatctttc ttggcatcct tgaaggacaa agctccgttt
     3421 ggccagtttt cagatggttt ttcaacatcg tcccaagtcc atagtccttg agcatccttg
     3481 ttttcttcag gaagtttttt gacatggata cggaagtagt tatcttcgat gggctcttct
     3541 gccttagttt cagttgttac tggactagta gaagtagttg gctctgttgc aggtttttct
     3601 tctgttttct ctagggaagc gtttgcattt ctaggtgaag aaatatcact ttcgttctta
     3661 ccagagccag ctgctgtatc agtaagaggt tgggcaaggg tggttgtatt tctgttgttg
     3721 ggttcgttag tggttggtgt actttcgtcg gatgagatag ttggtgtagc catggcaagc
     3781 aagacaaggc ttgcgccgat aaggacagaa ccagttccat ttttgaggga acggatgctg
     3841 tagaccattt ttttctcagt gtgagatggt gtttttctca taatgattct ccaatcaata
     3901 aatttctata tcagtatagc atgtagtaaa acaatatgca agcgttttct ttgatttgtg
     3961 aaaaaaattc ttacttttga gaagttttct gtactatttt atatatcagt ataaatgacg
     4021 gagataaaaa tgtcacataa gccaagccgt attattagga agatgatgtg ttcccagcta
     4081 tttttattca gaaattgatc tctaacatta ccaataaaaa agaaaaatat cttgacaagc
     4141 aagggaaaat tttgttacaa taatagacgg tactttttac ttttggtctc tcaagagtgt
     4201 acagggacgt gctgacaaat gttgcaaaag tacacacaga tgatatctgt caccaagtgt
     4261 atcatcacca aaaataaaaa aacacaggag aatgtagatg cctacaatta accaattggt
     4321 tcgcaaaccg cgtaaatcaa aagtagaaaa atctaaatca ccagctttga acgttggtta
     4381 caatagtcat aaaaaagttc aaacaaacgt ttcttcaccg caaaaacgtg gtgttgcaac
     4441 tcgtgttgga acaatgacac ctaaaaaacc taactcagcc cttcgtaaat tcgctcgtgt
     4501 acgtttgagc aaccttatcg aagttactgc ctacatccca ggtatcggac acaacttgca
     4561 agagcacagc gtggtgcttc ttcgcggtgg acgtgtaaaa gaccttccag gggtacgtta
     4621 ccatatcgtc cgtggtgcac ttgatactgc aggtgttaac gatcgtaaac aaggccgttc
     4681 taaatacggt actaaacgtc caaaagcata aggaaagggg ataaagagaa atgagtcgta
     4741 aaaatagagc tccaaaacgt gacgtattgc cagatccgct atacaattca caactagtta
     4801 ctcgtcttat caaccgcgtt atgcttgatg gtaaacgtgg tactgctgct tcaatcgttt
     4861 acggtgcttt tgagcaaatc aaagaagcta ctggcaacga tgcacttgaa gtatttgaaa
     4921 cagctatgga aaacatcatg cctgtacttg aagtacgtgc acgtcgtgtt ggtggttcta
     4981 actaccaagt cccagttgaa gttcgtccag aacgtcgtac aacacttgga cttcgttggt
     5041 tggtaacaat cgctcgtctt cgtggtgaac acacaatgca agaccgtctt gcaaaagaaa
     5101 tcttggatgc tgctaacaac actggtgcag cagttaagaa acgtgaagat actcaccgta
     5161 tggctgaagc taaccgtgca ttcgcacact tccgttggta agataggatg cgaaagcgtt
     5221 aagaaagtcc cagagaaaat agggaatcga agcaggttgc ggttgcaacc aatgagattc
     5281 atctttttct ccagactttt agcttgagct caactaaatc atgatgctag gaacggtaag
     5341 gatgcaaggt gaaaatagga aactgacgca gtattcgacg aatacaagga gttttatctt
     5401 tttcacgcag catcccgttc cagctcacat cggctaacta actttagccc gggttcaaat
     5461 tagctaaatc gattagtatt agctataact caacttacca tctcgtaagt tgaaaccaac
     5521 aatagcatga aaacattgag aacgggtagg tcctgcctat ccgtttttat taaaatcgtg
     5581 ttataataga atagaaatca aaaataaata ggagaaacaa acctcatggc acgcgaattt
     5641 tcacttgaaa aaactcgtaa tatcggtatc atggctcacg tcgatgccgg taaaacaaca
     5701 actactgagc gtattcttta ctacactggt aaaatccaca aaatcggtga aactcacgaa
     5761 ggtgcgtcac aaatggactg gatggagcaa gagcaagaac gtggtatcac gatcacatct
     5821 gctgcgacaa cagctcaatg gaacaaccac cgcgtaaaca tcatcgacac accaggacac
     5881 gtggacttca caatcgaagt acaacgttct cttcgtgtat tggatggtgc ggttaccgtt
     5941 cttgactcac aatcaggtgt tgagcctcaa actgaaacag tttggcgtca agcaactgag
     6001 tacggagttc cacgtatcgt atttgctaac aaaatggaca aaatcggtgc tgacttcctt
     6061 tactctgtaa gcacacttca cgatcgtctt caagcaaatg cacacccaat ccaattgcca
     6121 atcggttctg aagatgactt ccgtggtatc attgacttga tcaagatgaa agctgaaatc
     6181 tatactaacg accttggtac ggatatcctt gaagaagaca tcccagctga ataccttgac
     6241 caagctcaag aataccgtga aaaattgatt gaagcagttg ctgaaactga cgaagaattg
     6301 atgatgaaat acctcgaagg tgaagaaatc actaacgaag aattgaaagc tggtatccgt
     6361 aaagcgacta tcaacgttga attcttccca gtattgtgtg gttcagcctt caaaaacaaa
     6421 ggtgttcaat tgatgcttga tgcggttatc gactaccttc caagcccact tgacatccca
     6481 gcaatcaaag gtattaaccc agatacagac gctgaagaaa ctcgtccagc atctgacgaa
     6541 gagccatttg cagctcttgc cttcaagatc atgactgacc cattcgtagg tcgtttgaca
     6601 ttcttccgtg tttactcagg tgttcttcaa tcaggttcat acgtattgaa tacttctaaa
     6661 ggtaaacgtg aacgtatcgg acgtatcctt caaatgcacg ctaacagccg tcaagaaatc
     6721 gacactgttt actcaggtga tatcgctgct gccgttggtt tgaaagatac tacaactggt
     6781 gactcattga cagatgaaaa agctaaaatc atccttgagt caatcaacgt tccagaacca
     6841 gttatccaat tgatggttga gccaaaatct aaagctgacc aagacaagat gggtatcgcc
     6901 cttcaaaaat tggctgaaga agatccaaca ttccgcgttg aaacaaacgt tgaaactggt
     6961 gaaacagtta tctcaggtat gggtgaactt caccttgatg tccttgttga tcgtatgcgt
     7021 cgtgagttca aagttgaagc gaacgtaggt gctcctcaag tatcttaccg tgaaacattc
     7081 cgcgcttcta cccaagcacg tggattcttc aaacgtcagt ctggtggtaa aggtcaattc
     7141 ggtgatgtat ggattgaatt tactccaaac gaagaaggta aaggattcga attcgaaaac
     7201 gcaatcgtcg gtggtgtggt tcctcgtgaa tttatcccag cggttgaaaa aggtttggta
     7261 gaatctatgg ctaacggtgt tcttgcaggt tacccaatgg ttgacgttaa agctaagctt
     7321 tatgatggtt catatcacga tgtcgactca tctgaaactg ccttcaagat tgcggcttca
     7381 ctttccctta aagaagctgc taaatcagca caaccagcta tccttgaacc aatgatgctt
     7441 gtaacaatca ctgttccaga agaaaacctt ggtgatgtta tgggtcacgt aactgctcgt
     7501 cgtggacgtg tagatggtat ggaagcacac ggtaacagcc aaatcgttcg tgcttacgtt
     7561 ccacttgctg aaatgttcgg ttacgcaaca gttcttcgtt ctgcatctca aggacgtggt
     7621 acattcatga tggtatttga ccactacgaa gatgtaccta agtcagtaca agaagaaatt
     7681 attaagaaaa ataaaggtga agactaatcc gtcctcactc taaaaggaag tcacttagtg
     7741 gcttcctttt gtctttagaa aatacctcta aatatggtaa aatagtagaa gaataatgtg
     7801 aggaaaatga atgtcaaata gttttgaaat tttgatgaat caattgggga tgcctgctga
     7861 aatgagacag gctcctgctt tagcacaggc taatattgag cgagttgtgg ttcataaaat
     7921 tagtaaggta tgggagtttc atttcgtatt ttctaatatt ttacctattg aaatcttttt
     7981 agaattaaag aaaggtttga gcgaagaatt ttctaagaca ggcaataaag ctgtttttga
     8041 aattaaggct cggtctcaag aattttcaaa tcagctcttg cagtcctact atagggaggc
     8101 tttctctgaa ggtccatgtg ctagtcaagg ttttaagtcc ctttatcaaa atttgcaagt
     8161 tcgtgctgag ggcaatcagc tatttattga aggatctgaa gcgattgata aggaacattt
     8221 taagaagaat catcttccta atttagccaa acaacttgaa aagtttggtt ttccaacttt
     8281 taactgtcaa gtcgagaaga atgatgtcct gacccaagag caggaagagg cctttcatgc
     8341 tgaaaatgag cagattgttc aagctgccaa tgaggaagcg ctccgtgcta tggaacaact
     8401 ggagcagatg gcacctcctc cagcggaaga gaaaccagcc tttgattttc aagcgaaaaa
     8461 agctgcagct aaacccaagc tggataaggc ggagattact cctatgatcg aagtgacgac
     8521 agaggaaaat cgtctggtat ttgaaggggt tgtttttgat gtggagcaaa aagtgactag
     8581 aacaggtcgt gttttaatca actttaaaat gacggactac acttcaagtt tttctatgca
     8641 aaagtgggtt aaaaacgagg aagaggccca gaagtttgac ctcatcaaga agaattcttg
     8701 gctccgagtt cgagggaatg tggagatgaa taacttcaca cgcgatttga ctatgaacgt
     8761 acaggatctg caggaagttg ttcactatga gcggaaggat ttgatgccag aaggtgagcg
     8821 tcgggttgag tttcatgctc atactaacat gtcgactatg gatgctttgc cagaggtcga
     8881 agagattgtt gcaacagctg ctaagtgggg acacaaggcg gttgctatca cggaccatgg
     8941 gaatgtccag tcctttccac atggctataa ggcggctaag aaagcgggaa tccagctgat
     9001 ctatgggatg gaagccaata tcgtggagga ccgtgtccct atcgtctata acgaagtgga
     9061 gatggacttg tcagaagcaa cctacgtggt ctttgacgtg gaaacgacgg gactttcagc
     9121 tatctataat gacttgattc aggttgcggc ctctaagatg tacaagggga atgttattgc
     9181 tgaatttgat gaatttatca atcctgggca tcccttgtca gtctttacta cagagttaac
     9241 tggaattaca gatgatcatg tcaaaaatgc caaaccacta gaacaagttt tgcaagaatt
     9301 ccaagaattt tgcaaggata cggtcctagt tgcccacaat gctacctttg acgttggctt
     9361 tatgaatgct aattatgagc gtcatggtct tccaaagatt agtcagccag ttattgatac
     9421 gctggagttt gctagaaacc tctatcctga gtataaacgc catggtttgg ggcctttgac
     9481 caagcgtttt ggtgtggcct tggaacatca ccacatggcc aactacgatg cggaagcgac
     9541 tggtcgtctg cttttcatct ttatcaaaga ggtagcagaa aaacatggtg tgaccgattt
     9601 agctagactc aacattgatc taatcagtcc agattcttac aaaaaagctc ggatcaagca
     9661 tgcgaccatc tatgtcaaga atcaggtagg tctaaaaaat atctttaagc tggtttcctt
     9721 gtctaatacc aagtattttg aaggagtgcc acggattccg agaacggttc tagatgccca
     9781 tcgagagggc ttgattttag gttcagcctg ttcagagggt gaagtttttg acgtggtcgt
     9841 ttctcaaggt gtggatgcgg cggttgaggt ggccaagtat tatgacttta tcgaggtcat
     9901 gccaccggct atctatgcgc ccttgattgc taaagagcag gtcaaggata tggaggaact
     9961 ccagaccatt atcaagagtt tgatagaggt tggagaccgc cttggcaagc ctgttttggc
    10021 tacgggaaat gttcactata tcgaaccgga agaagagatt tatcgtgaaa ttatcgtccg
    10081 tagtttggga cagggtgcga tgattaaccg aactatcggt catggtgaac atgcccaacc
    10141 agcaccactt ccaaaggctc attttcgaac gactaatgag atgttggatg aatttgcctt
    10201 tttgggagag gaactggctc gtaaactggt tattgaaaac accaatgcct tggcagaaat
    10261 atttgaaccc gttgaagtcg ttaagggtga cttgtatacg cctttcatcg acaaggctga
    10321 agaaacagtt gctgagttga cctataagaa agcttttgag atttatggaa atccgctgcc
    10381 agatattgtt gatttgcgga ttgaaaaaga attaacatcc atactgggga atggatttgc
    10441 tgtgatttat ctggcatcgc agatgctggt gcaacgttct aatgaacggg gttatttggt
    10501 tggttctcgt gggtctgtcg gatctagttt cgttgcgacc atgattggga ttacggaggt
    10561 caatcctctc tctcctcact atgtctgtgg tcagtgtcag tacagtgagt ttatcacaga
    10621 tggttcgtac ggttcaggat ttgatatgcc ccataaggac tgtccaaact gtggtcacaa
    10681 actcagtaaa aacggacagg atattccgtt tgagaccttc cttggttttg atggggataa
    10741 ggttcctgat attgacttga acttctcggg agaagatcag cctagcgccc acttggatgt
    10801 gcgtgatatc tttggtgaag aatatgcctt ccgtgcggga acagttggta cggtagctgc
    10861 caagactgcc tatggatttg tcaagggtta cgagcgagat tatggcaagt tttatcgtga
    10921 tgcagaagta gaacgcctcg ctcaaggagc ggcgggtgtc aagcggacaa caggccaaca
    10981 cccgggggga atcgttgtta ttccgaacta catggatgtc tacgatttta cgcctgtcca
    11041 gtatccagca gatgatgtca cggctgaatg gcagaccact cactttaact tccacgatat
    11101 cgatgagaac gtcctcaaac tcgatgtact gggacatgat gatccgacca tgattcgaaa
    11161 acttcaggat ttgtctggta ttgaccctaa taaaattcct atggatgacg aaggcgtgat
    11221 ggcactcttt tctgggactg atgtgctagg ggtaacacct gaacaaattg gaacgcctac
    11281 gggtatgttg gggattccag agtttggaac aaatttcgta cgtggaatgg tagacgaaac
    11341 ccatccgaca acctttgcgg aattgcttca gctgtctggt ctgtcccacg gtactgatgt
    11401 ttggttgggg aatgctcagg atctgattaa gcaaggaata gcggacctat cgactgttat
    11461 cggttgtcgg gacgacatca tggtttacct catgcatgcg ggtctggaac ctaagatggc
    11521 ctttaccatt atggaacggg tacgtaaggg tttgtggcta aagatttcag aagaggagag
    11581 aaatggctat atcgaagcca tgaaggctaa taaggtgcca gagtggtata tcgaatcctg
    11641 tgggaaaatt aagtacatgt tccctaaggc ccatgcggca gcctacgtta tgatggcctt
    11701 gcgtgtagct tacttcaagg ttcaccatcc tatttattac tactgtgctt acttctccat
    11761 tcgtgctaag gcttttgata tcaagaccat gggtgcgggc ttggaggtca tcaagcgcag
    11821 aatggaagaa atctctgaaa aacggaagaa caatgaagcc tctaatgtgg aaatcgatct
    11881 ctatacaact cttgagattg tcaatgagat gtgggaacga ggtttcaagt ttggtaaatt
    11941 agatctctac tgtagtcagg cgacagagtt cctcatcgac ggggataccc ttatcccacc
    12001 atttgtagca atggatggtc tgggagagaa cgttgccaag caactggtgc gggcgcgtga
    12061 agagggagaa ttcctctcta aaacagaact acgcaagcgt ggtggactct catcaacctt
    12121 ggttgaaaag atggatgaga tgggtattct tggaaatatg ccagaggata accagttgag
    12181 tttgtttgat gagttgtttt aaaaaattgc ttaataatct attaaaagag gctaacgtat
    12241 atccaataga tttacattag ctttcttttt tgttaaaata gtctatggaa agagggtgag
    12301 agtatgtcaa agatgagtat aagcatccgt ctggatagtg aggttaagga gcaggcccaa
    12361 caggtgttta gtaatctggg aatggatatg acaacagcta ttaatatttt ccttcgtcag
    12421 gcaattcaat atcagggatt accttttgat gttagactag acgaaaatcg gaagttgctc
    12481 caagcgttaa cggatttaga ccaaaatcgt aatatgagcc agtcttttga atcagtctca
    12541 gatttgatgg aggacttacg tgcttaagat tcgttatcat aaacagttta aaaaagattt
    12601 taagttggct atgaagcgtg gtttgaaggc agaattatta gaagaagttt tgaattttct
    12661 ggttcaagaa aaagaacatc ctgccagata tcgtgatcat tcattgacgg catccaagca
    12721 ttttcaagga gttcgtgaat gccataccca gccagattgg cttttggttt ataaagtaga
    12781 caagtcggaa ttgattttaa atttgctgag gacaggcagt cacagtgatt tattttaatc
    12841 tattttaagg gggttctcat gaaactaaga atatttgcgg aagataagcc ggctaagaag
    12901 gtatttgaat atcaattaga acttgctgat cgtacaattc ttctatcgac agcactcttg
    12961 tcaggtgcta ttgctttagc aggaatcttt tctgctttga aagaaaaata aaaatagaaa
    13021 agagaaaaca gaatggtttt accaaatttt aaagaaaatc tagaaaaata tgcgaaattg
    13081 ttggttgcaa atggaatcaa cgtgcaacct ggtcacactt tggctctctc tatcgatgtg
    13141 gagcaacgtg agttggctca cttaatcgtc aaagaagctt atgctctggg tgcgcatgag
    13201 gttatcgttc agtggacaga tgatgtcatt aaccgtgaga aattcctcta tgcgccaatg
    13261 gagcgtttgg acaatgtgcc agaatacaag attgctgaga tgaactatct tttggagaac
    13321 aaggctagcc gtcttggggt tcgttcatct gatccaggtg ccttgaacgg agtggatgct
    13381 gacaagcttt cagcttctgc taaagctatg ggacttgcca tgaagcctat gcgtatcgca
    13441 actcaatcta acaaggttag ctggactgta gcagccgctg ctggacttga atgggctaag
    13501 aaagtcttcc caaatgctac gagcgatgaa gaagcagtcg atctcctttg ggaccaaatc
    13561 ttcaaaactt gccgtgtcta cgaagcagat cctgttaagg cctgggaaga gcatgcagct
    13621 atcttgaaga gcaaggccga tatgcttaat aaggagcaat tttcagccct tcactacaca
    13681 gcgccaggaa cagatttaac acttggtttg ccaaagaacc acgtttggga atcagctggt
    13741 gctgtcaatg cacagggcga agaattcttg ccaaatatgc cgacagaaga ggtcttcaca
    13801 gcgcctgact tccgtcgtgc agatggttat gtcacttcta caaaaccgct tagctacaac
    13861 ggaaatatca ttgaaggcat taaggtgacc tttaaggatg gacaaatcgt agatatcact
    13921 gctgagaagg gtgatcaggt tatgaaagac cttgtctttg aaaatgcggg tgcgcgtgcc
    13981 ttgggtgaat gtgccttggt accagatcca agtccaattt ctcagtcagg cattaccttc
    14041 tttaacaccc ttttcgatga aaatgcgtca aaccacttgg ctatcggtgc agcctatgcg
    14101 actagcgttg ttgatggagc ggagatgagc gaagaggagc ttgaagctgc agggcttaac
    14161 cgttcagatg ttcacgtaga ctttatgatt ggttctaacc aaatggatat cgatggtatt
    14221 cgtgaggatg gaacgcgagt acctcttttc cgtaatggga attgggcaaa ttaaggagat
    14281 aatatgttag gaagtatgtt cgttggtctc ctagtgggat ttttagcagg tgctatgacc
    14341 aatcgtggag agcgaatggg atgttttgga aaaatgtttc tcggttggat cggagccttt
    14401 ctaggtcact tgctctttgg aacttggggg ccagttttat caggaacagc tattatccca
    14461 gcgattttag gagccatgat tgttttagct attttttgga gacgaggaag ttaatttcct
    14521 aaatctgata ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa
    14581 agcactgctt tgaggttgca gatagaactg acgaagtcag taacatatat acggcaaggc
    14641 gacgttgacg cggtttgaag agatttttga agagtatgaa acgaaaagga ggttggtcat
    14701 tgtactagcc tccttttgat atgatataat agttctatga gattagataa atttttagtt
    14761 gcctgtgcgg tgggaagtcg gactgaggtc aaaaacttgc tcaaggctgg gcgcgtgact
    14821 gtaaatggta aaaaagaaaa atcagctaaa ctgcagattg atgaaaaaat agatgagatt
    14881 cgctttgatg ggcaagtgtt ggagtatgaa gagtttgtct actacatgat gaacaagccc
    14941 aaaggagtta tctcagcgac tgaggatccc aagcacagaa ccgttctgga cttgttggat
    15001 gacttggcgc ggagtaagga agttttccca gtaggacgct tggatattga cacgcatggt
    15061 cttttgctct tgaccaataa tggtcagctg gctcatgttc ttctttcgcc aaagcgtcat
    15121 gtggacaaga cttatctggc acaagtcaag ggaatcatga cccaagaaga tgtggagaca
    15181 tttgctgagg gtattccgct caaagacttt acctgtcaac ccgctatact ggagcttgta
    15241 tccatagata cagaaaagaa tcaaagccaa atacgtgtga ccattgcaga agggaagttt
    15301 catcagatca agcgtatggt gggctactgt ggcaaggaag tggtggactt gcaacgattg
    15361 actatgggaa ctttagtatt agatgagaac ctggaacgag gggaatggcg tcgcttgacc
    15421 aaggaagaat tagaaattct ccttgctaat at
//
LOCUS       DAVDFK010000042        15372 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.42, whole genome shotgun sequence.
ACCESSION   DAVDFK010000042 DAVDFK010000000
VERSION     DAVDFK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.42"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            173..1936
                     /gene="aspS"
                     /locus_tag="VUR04_001696"
     CDS             173..1936
                     /gene="aspS"
                     /locus_tag="VUR04_001696"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET5341567.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1914..2855
                     /locus_tag="VUR04_001697"
     CDS             1914..2855
                     /locus_tag="VUR04_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET5341568.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(3146..4132)
                     /locus_tag="VUR04_001698"
     CDS             complement(3146..4132)
                     /locus_tag="VUR04_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5341569.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4142..4942)
                     /locus_tag="VUR04_001699"
     CDS             complement(4142..4942)
                     /locus_tag="VUR04_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET5341570.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5195..6037)
                     /locus_tag="VUR04_001700"
     CDS             complement(5195..6037)
                     /locus_tag="VUR04_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5341571.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6039..7331)
                     /locus_tag="VUR04_001701"
     CDS             complement(6039..7331)
                     /locus_tag="VUR04_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5341572.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7442..8713)
                     /locus_tag="VUR04_001702"
     CDS             complement(7442..8713)
                     /locus_tag="VUR04_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5341573.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9264..10781
                     /gene="malQ"
                     /locus_tag="VUR04_001703"
     CDS             9264..10781
                     /gene="malQ"
                     /locus_tag="VUR04_001703"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET5341574.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPFLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10807..13065
                     /gene="glgP"
                     /locus_tag="VUR04_001704"
     CDS             10807..13065
                     /gene="glgP"
                     /locus_tag="VUR04_001704"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET5341575.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14109..14681)
                     /locus_tag="VUR04_001705"
     CDS             complement(14109..14681)
                     /locus_tag="VUR04_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341576.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
BASE COUNT         4590 a         2870 c         3275 g         4637 t
ORIGIN      
        1 tactacggta aggcgacgct gacgtggttt gaagagattt tcgaagagca ttagcgctaa
       61 tttttagggc tttcacctga cttttaaaga ctggcaaact tttctgatga ttttcatgaa
      121 gagcctgcgc ttttatggta aaatagtaac agaataaaag aggagagaaa taatgaaacg
      181 tagtatgtat gctggtcgtg ttcgtgagga acacatcgga caagaaataa ccttgaaagg
      241 atgggttggc cgtcgtcgtg accttggtgg tttgatcttt atcgatcttc gtgaccgtga
      301 aggaatcatg cagttggtta tcaaccctga aaaagtatct gcagaggtta tggcaacagc
      361 tgaaagcctt cgtagcgaat ttgttattga ggtgactggt caggtcgctg cgcgtgagca
      421 agccaatgat aagttgccaa ctggtgcggt tgagttaaac gtgacagctc ttattgtgct
      481 taacacagct aagacaacac catttgagat taaggatggc attgaggcaa atgacgatac
      541 acgtttgcgt taccgttacc ttgaccttcg tcgtccagaa atgttggaaa atcttaaact
      601 tcgtgccaag gtgacccact ctatccgcaa ctacttggat gagttggagt ttatcgacgt
      661 ggagacacca ttcctttcta agtcaacgcc tgaaggggcg cgtgattatt tagtgccgtc
      721 tcgtgttaat aaggggcatt tttacgctct tcctcaaagt ccacaaatca cgaaacagct
      781 cttgatgaat gctggttttg accgttacta ccaaatcgtt aaatgtttcc gtgacgagga
      841 cttgcgtgga gaccgccagc ctgaatttac tcaggtcgac ttggaaacgt ccttccttac
      901 tgagcaagaa atccaagata ttacagaagg cttgatcgcg cgcgtgatga aggaaacaaa
      961 aggcatcgaa gtaacgctac cgttccctcg tatgaaatac gatgatgcta tggctcttta
     1021 cggttctgac aagccagata ctcgttttga catgttgctt caggacttga cagaagtggt
     1081 caaaggtgta gactttaaag tcttttcaga agcacttgct gtaaaagcga ttgtggtcaa
     1141 aggagctgcg gacaactatt cacgtaaaga catcgacaag atgacggaag tagccaaaca
     1201 gtatggtgcc aaaggtcttg cttgggtcaa ggtggttgat ggagaattaa acggaccagt
     1261 tgccaagttc ttgactggta tccaagaaga attgacaaca gcgcttgctc ttgaagataa
     1321 ggacttggtt ctctttgtgg cggatacgct tgaagtggct aatgcaacac tgggtgccct
     1381 tcgtggacgt attgctaaag agcttggctt gattgataat gataagttca acttcctttg
     1441 ggtggttgac tggccgatgt ttgaatggtc tgaagaagaa ggccgctaca tgagcgccca
     1501 ccatccattc acacttccac aggaagagac tgctcacgaa ttagaaggtg atttggctaa
     1561 ggttcgtgcc attgcttacg atatcgtctt gaacggttat gagcttggtg gtggtagcct
     1621 tcgtatcaac caaaaagacc ttcaagaacg catgttcaag gctcttggtt tctcagctga
     1681 agaagccaat gaccagtttg gtttccttct tgaagccatg gactatggtt tcccaccaca
     1741 cggtggtttg gctatcgggc ttgaccgttt tgtcatgttg cttgctggag aagaaaatat
     1801 ccgtgaagtc attgcctttc ctaagaacaa caaggcaact gacccaatga cacaagctcc
     1861 atcaacagtc gctctcaaac aactagagga actcagctta caagtagaag aagatgaaac
     1921 aaacaaaacg aattaagcgg tggcgctatt atctgcgccg ctttgcttat cagataaaaa
     1981 ttttacgtgt cttacaaagt atctctcgag aaaagtatga tgagaagatt tcggcctctc
     2041 tggtctatgg ttttttatca gcagtagcag ttaatttctt tttccaacca gggcatgtgt
     2101 attcgagtgg tgcaacaggt ctggcacaga ttatctctgc cttgagtaat cactggtttg
     2161 gttttcatat tccgatttcg ctaagcttct acgccattaa cttccctttg atggtcttag
     2221 cttggtatca gattggccat aagttcaccg tctttacctt tatcacggta tctatgagtt
     2281 ccttctttat ccagtttgtc cctgtggcaa ccttgacgga ggatcccatt atcaattccc
     2341 tttttggggg tgttgttatg ggtttgggga ttggttttgc tcttcgaaac aatatctcca
     2401 gtggtgggac ggatatcgtc agcctgacta ttcgcaagaa aacgggtaag aatgtcggta
     2461 gtatttcttt cttggtaaat ggaactatca tgctgatagc aggtttgacc tttggttgga
     2521 aatacgctct ttattctatg attaccatct ttgtctctag ccgtgtgaca gacgcagtct
     2581 ttactaagca aaagcgtatg caggccatga ttgtgacaaa tcatccagag aaggtaattg
     2641 aaaaaatcca taaaaaattg caccgcggag caaccatgat ccacgatgca gaaggaacct
     2701 ataatcacga gagaaaggca gttttaatca ctgtcattac acgtgcagag tttaatgaat
     2761 ttaaacagat tatgacacaa gtggatccaa gctcctttgt ctctgtctcg gaaaatgttc
     2821 atattctagg aagatttgtt gagatagata attagtgatt aatactcttc gaaaatctct
     2881 tcaaaccacg tcagcgtcgc cttgccgtag gtatgttact gacttcgtca gttctatctg
     2941 caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgc actttgattt
     3001 ttattgagta taaaaagatc ttgggtaaca actcaatttc agaagaaaag gaagtaaatc
     3061 ttcccacaat aaaacgcata ctatcaagtt ttttcaatac ctgatagtat gcgtttttgc
     3121 ttttaacgac tttttgccca gtctcttatt tttcgataat tttgtgggcg atcaattgac
     3181 ggtaacaaat ttgtttattg tttttattat cattaataat ctggagaata gtttcaaggg
     3241 aaacacgacc aagctctaaa ctattgatat cgacataggc tgccaagttg agcttgggat
     3301 taaccgagtc aaagctgaga acagggacat ccagctggtg tttggcaata tagttacaaa
     3361 caccttcagc taggaggcta tcggttgtga tgatagcatc aatttgtgga tcgtgcttga
     3421 ataatcgctt gctaaattta tagccctttt cttccagaaa ctcgtcggca aagtagatgc
     3481 gattgttgtc agtggtaagt ttgtaatgtt taagcgcctg ttcatagccc gttaaacggt
     3541 ctttggtcac gaagagcttt ttacttcctc cgataaaggc aatgcgtttg cagccttttt
     3601 tgatgaaata ttcagtcgca tcaaaaccag cttgaacatt gtcgttgtcg acaagtggga
     3661 tgaaaggaga tagagattta cctaagataa ggaaggggaa ctgttcttct gcgacgagtt
     3721 ttacgagagg gtcttcttct tgggcataga gaaagattag cccatctaca cgcttgccgt
     3781 agaccatttg tgaaatagcg ttgagacgct ccttctcatc tttccctgtt gctatctgaa
     3841 tggcatagtg gttttcagat gcgacttgag agatgccacg tagaaccgat ggaaagaaag
     3901 gattctggta gaaggcgtct gagtcatcag gaagaactaa tccgataacc tgagtatagc
     3961 tgcttaccaa gctacgagcg ttgaggtttg ggtggtagtt gagttccttc atagctttgc
     4021 gaacgcgttt ttttgtttcg tcgctaatgg ttgatttatt ttgaataaca cgggttacgg
     4081 ttgaaggcga aacaccagca gccttggcca cgtctttaat cgtaacgggc ataaaaatct
     4141 cctatttatg gtaatttgga tcacggaaat gtgttttata aaagatagtg accagataca
     4201 gaacaaaaag aatattttgt acagtaatca gggttgtcat attttggcca aataatccca
     4261 aaataagtgt aatcagagtc ggcaatccta aacagttcaa gataaagtga tagcactctt
     4321 taaaggttct aaatgaaaag aggcgtgatt tcttagtgat ataaaggaga agactagctc
     4381 ctagagagac gataaagaaa ttcaaaccaa agaggaagct cgcaccgaga actaggaaga
     4441 ggctgatata gacacgattt tgttggtacc agtctttaga aattgcttgg gtcaagctgt
     4501 ctttgctttt gaaactctca gtctgaatgg ctcggtaaga gatgcgggtc agttccttgc
     4561 tttccttgct gatgactagc tcatttgtat cgaaatgcag ttgcaagttc ttaggtaatt
     4621 ccttgatttg acttggacca atcacaacag aagaggcttg actaactgtt ccagtataag
     4681 ttaatgtgcc atcgacaatt gtagcatgtt cagaaagatc ctggacaacc tcatttgtca
     4741 gaggttcata gacattatcg ataaaagttt ctagcggata ggtctcctgg gagctgtttt
     4801 ggatagcaat gggtaccata gacaagctga taaggaagat actggtaaag agaagttgaa
     4861 accagttgag cccgaaacgt ttggacaggg gcttacgaaa ccccaaaata cttgaaaaaa
     4921 aggaaaatgg atatggaagc ataggtatct ttctaaaagg tgttttctat ataagtatta
     4981 ttatatagag aaatgcgctt tatttcaagt ctaggagaaa aattgcttgc tacaaggata
     5041 ttatttacag tgacaattgc taatagtcaa tgaaaatcaa agtgcaaact agccacaggt
     5101 tgctcaaagc acaactttga ggttggagat aaagctgacg tggtttgaag agattttcga
     5161 agagtataaa atgaaaaagg gtggcgggga taaattatcc cttgtcgcca ccacttgtaa
     5221 gtcctgaaac aaagttcttt tgtaggaaga agaagagaat acagattgga agggcgatga
     5281 ggatagcacc tgctgagaag taggcaatct tcaagttttt cgcattgtta acgaaggttt
     5341 ggagacctac ggcaacagta aagtattctt tctcacgaag caagaaacta gagaggatgt
     5401 agtccccgaa aggtcccatg aaggcccaga gagcttgtac ggcaaccatt gggcgaacaa
     5461 gtggaagaac aatttgccag aagcggcgga agtgtcctgc accgtctagt tttgcagatt
     5521 cgtctaaaga cattggcact gtatcgaagt agcctttcat gagccaagca ttcatcggga
     5581 taccaccacc aacgtagagg aagatgagga accagttgtg gttaagggcg ttcaacataa
     5641 gcgccataac gaagaaggct gtcaaagcgg ccatagttgg caccatttgg atgatcaaga
     5701 agaagaccaa actttgttta cgagccaaga agttgtaacg gctgtaagca taaccagcaa
     5761 gtacgatgat acttgtttga acagccatgg taattaaggc gataatcaaa gtgttgaggt
     5821 accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa gttatcaaaa ttgaggtcga
     5881 tattagtatc tagtttaaag gctgagacat tacctgcttt aaaggctgac ataatggtaa
     5941 tcaacagtgg atagataatt acaattgata gaccaatcag gtaaaggtaa gtaaggcttt
     6001 gagtcagtct acgtttgagt ttaattgagt tattcatctt agacgtcctc catatcaaat
     6061 gcgtgtagtt tcttgaatgc gatcatagag attgagatga caatgataga gataatcaag
     6121 gtaacagctg ccgccattga gtattgagga gatgtacctg ttgtcaaacg gtagatccat
     6181 gagatcaaga tatcggttga accagctcca cctccgacac taccaggtcc tccaccattg
     6241 aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt attggctaat caaagtaggt
     6301 gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga atttttgcca agcgttggca
     6361 ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag attgcaagat acccaaagtc
     6421 aaaacgtaga tgtatgggaa tccgagccaa ccttgcatca taatcaaggc aatcttagtc
     6481 caagttgggt ctgttttcca aggaataaga gctccatcaa ggaaaggaag gaatttagcc
     6541 aagattggca atacttgagt gttgatagca ccgacactat cgttaaacat gtttgagaat
     6601 gtcaagatag tgatgaaggc tgggacagcc caaggaagaa ggaaaataac accaaagata
     6661 cgttttcctt tgataaatgg ttggttggca atgatagctg tgaagatacc aattacgatt
     6721 tgtaaagtag aagctgccaa agcccaaatg atagtccaag aaagaacaga accaaaggca
     6781 gaacggaagg tactcaagct ccaaatgttt gtaaagttgg tcaaaccaac ccagtccaac
     6841 aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa aggcgatcat caaggttacg
     6901 ataactggga agataatcgc gaaggtcatg gcaacataag atggaatgat caagaggtaa
     6961 gggaagccat tttcataaat ccctttgatc atgtctttga gtgtgcgtgg aactggaatt
     7021 ccattgttaa tgcgttttgc aatcgtatgt gcatctttga tatttgagaa ataaaagagt
     7081 acataaacga ttacaaagat tagatggaag gcaccacgaa tcagcataaa gagggaatta
     7141 tcacgacctg gtttgtcacc aagagtgatg aggttgctca attcaggggt tgcaagtgct
     7201 aggaagtaaa ggacaaatac gatggttaca ccaaggaaga taaaaccttt ggctttttgt
     7261 ttattgtaaa tttgtcctaa cccaggaatg atagacagca gggctgcttt actaggttgt
     7321 tgcttttcca tattaactcc tttcatagga tactactttt ttataagaaa gctaaattat
     7381 ttgtgtctct attgataaat tcaaaggggg atttgatttc cacccccctt gaacaaattt
     7441 tttattcacc aaatttttgt ttgattgttt ctttgatcaa tgttacagca tcgttagcag
     7501 ctgttttagc atctttttga ccacttacag catcaaagag catatttttc gctggatccc
     7561 aaactgcaga catttgagag atgtttggca gtggttgagt gttcttgaac tgtttgataa
     7621 cagctgttgt caactcatcg tttttacctt cagcgtatga acgagcctca gtattagctg
     7681 ggatttcgtt agtcttatca tataatactt tttgttgttc agttgcaaca aggaagtcta
     7741 caaatttttg agaagcttca aggttcttaa cggcttgagg aatgacccaa gctttaccac
     7801 caccgaatgc agcatattct tttccatttg gaagagttgg gatagttgca actccgtagt
     7861 ttactttagc atctttaaag gcttgagctt tccaaggtcc gtcgatgata gcagctgttt
     7921 taccttcttg gaattgagtt tggattaagt ttccagcacc ttctgtatct tgcatacctt
     7981 taggccattt ttcgtaccaa gatttagcgt aattgatacc tacgatagaa ccgtcgtttg
     8041 caagaccgat gtctttagcg tctttaccgt tttggccaaa gacgtaagca ccgttaccgg
     8101 caagaagtcc atatgtatag tagaagtttg tccagtcagc taggaaggca gtagttttac
     8161 catcttcacc agcgaatgcg tatttgctat ctttagcaag gttttccaag tcagcaaatg
     8221 tttttggagc atctttcacc aagtctttgt tgtagtacat aacaagtgac tcgataacgg
     8281 caggagcacc gtaaacttta ccattagcag ctgttacaag agatttagtt gtgtcgtctg
     8341 ttttagcacc atcgctcaat ttcacttctg aaagttgtcc gtcagaacca aggctaccta
     8401 cacggtcgta tggagccatc ataacatcag ggacattacc agattggttg tcaagagaaa
     8461 gtttatcaag acctcctaga gcatcaccag ttttaagagt gacttttact ccagcttctt
     8521 tttcataagc tttagcaacc tcttcaatat agctcttata tccctcgtct acatatacag
     8581 tgagttcttt gacttcagat gaaccagaat cagcaggctt atcagcagtt ttgcttccgc
     8641 aagctaccaa aagcaagcta gcaagtgtaa cagttccaag caccgcagtg ctcttcataa
     8701 atttagatga catagtgtat tcctcccaaa gaatagcaag ttttattgat aaggaaacgc
     8761 aaacgttttc ctttatgagc ttagtatagc acaaatagaa aacggttgca agtatttttt
     8821 gtaaaaattt taaaaaattt ttaagcttga tttgatagca taattttgca ttttaataga
     8881 agaaaagtat gaaatagata agaatacagt atttttaata aaaaatatat ggaatctgtc
     8941 taaagaggga aatcaggagg ggctacctcc ctgtttctaa tccctatcta ttttctatag
     9001 acgtttgtgc tttgctgcat ataaattcaa gctccctaag gaggttttgt actttgtaga
     9061 ctgtctcgtg agagtcaaac tttaggatta gatagtttta agttatcttt gctaaaatga
     9121 gttagtctcc ttaaaaataa tcaaaaaagt tttttaaaaa cgcttgcaat tatgcttgaa
     9181 aaggagtata cttataagta acgcaaacgt ttgcgtctgc aaaatacgca acgttccatt
     9241 attttaacac acgaggtgct attatgaaaa aacgtcaaag tggtgtgttg atgcacatct
     9301 cttctcttcc aggagcttac ggaatcggat catttggtca aagtgcttac gacttcgttg
     9361 atttcttggt ccgtacaaaa caacgttact ggcaaatcct tccattagga gcaactagtt
     9421 acggggattc tccttaccaa tctttctcag ccttcgcagg aaacactcat tttatcgatt
     9481 tagatatctt ggtggagcaa ggtttgttgg aagcaagtga ccttgaagga gttgactttg
     9541 gtagcgatgc gtctgaagtt gactatgcta aaatctacta tgcacgtcgt ccttttttag
     9601 aaaaagcggt gaaacgtttc tttgaagtcg gagatgttaa agattttgag aaatttgctc
     9661 aagacaacca atcatggctt gagctctttg ctgagtatat ggctatcaaa gagcattttg
     9721 acaatcttgc ttggactgaa tggccagatg cagatgctcg tgctcgtaaa gcttcagcac
     9781 ttgaaagcta tcgtgagcaa ttggcagaca agttggttta ccaccgtgtg actcaatact
     9841 tcttcttcca acaatggttg aaattgaaag cttacgctaa cgacaaccac attgaaatcg
     9901 ttggggacat gccaatctac gtagcggaag attcaagtga tatgtgggca aatccacatc
     9961 tcttcaaaac agatgtcaat ggtaaggcta cttgtatcgc aggatgccca ccagatgagt
    10021 tttctgtaac tggtcagctt tggggtaacc caatctatga ctgggaagca atggacaaag
    10081 acggctacaa atggtggatt gaacgcttgc gtgaaagctt caaaatctac gatatcgttc
    10141 gtatcgacca cttccgtggc ttcgaatctt attgggaaat ccctgctggt tccgatacag
    10201 cagcacctgg tgagtgggtg aaaggtccag gctacaagct ttttgcagcc gttaaggaag
    10261 aacttggtga gctaaacatc atcgcagaag accttggctt catgacagat gaagtgatcg
    10321 aattgcgtga acgtactggc ttcccaggaa tgaagattct tcaatttgcc ttcaacccag
    10381 aagacgaaag cattgatagc ccacacttgg cacctgctaa ctcagttatg tacacaggaa
    10441 cacacgataa caatacggtt cttggttggt accgtaatga gattgatgat gcgactcgtg
    10501 agtacatggc tcgttacacg aaccgtaaag aatatgaaac agtggtacac gctatgcttc
    10561 gtacagtatt ttcatcagtt agctttatgg caattgcaac tatgcaagat ttactagaat
    10621 tggatgaggc agctcgtatg aacttcccat ctacccttgg tggaaactgg tcttggcgta
    10681 tgactgaaga tcaattgaca ccagctgtcg aggaaggttt gcttgacttg acaacaattt
    10741 atcgccgaat taatgaaaat ttggtagatt taaagaaata agacaataat caggagacaa
    10801 ctaaacatgt tatcactaca agaatttgta caaaatcgtt acaataaaac cattgcagaa
    10861 tgtagcaatg aagagcttta ccttgctctt cttaactaca gcaagcttgc aagcagccaa
    10921 aaaccagtca acactggtaa gaaaaaagtt tactacatct cagctgagtt cttgattggt
    10981 aaactcttgt caaacaactt gattaacctt ggtctttacg acgatgttaa aaaagaactt
    11041 gcagctgcag gtaaagactt gatcgaagtt gaagaagttg aattggaacc atctcttggt
    11101 aatggtggtt tgggacgttt ggctgcctgc tttatcgact caattgctac tcttggtttg
    11161 aatggtgacg gtgttggtct taactaccac tttggtcttt tccaacaagt tcttaaaaac
    11221 aaccaacaag aaacaattcc aaatgcatgg ttgacagagc aaaactggtt ggttcgctca
    11281 agccgtagct accaagtacc atttgcagac tttactttga catcaactct ttacgatatt
    11341 gatgttactg gttatgaaac agcgactaaa aaccgcttgc gtttgtttga cttggattca
    11401 gttgattctt ctattattaa agatggtatc aactttgaca agacagatat cgctcgcaac
    11461 ttgactctct tcctttaccc agatgatagt gaccgtcaag gtgaattgct ccgtatcttc
    11521 caacaatact tcatggtttc aaacggtgcg caattgatca tcgacgaagc aatcgaaaaa
    11581 ggaagcaact tgcatgacct tgctgactac gcagttgtcc aaatcaacga tactcaccca
    11641 tcaatggtga ttcctgaatt gattcgtctt ttgactgcac gtggtatcga gcttgacgaa
    11701 gcaatttcaa ttgttcgtag catgactgcc tacactaacc acacaatcct tgctgaagcg
    11761 cttgaaaaat ggcctcttga attcttgcaa gaagtggttc ctcacttggt accaatcatc
    11821 gaagaattgg accgtcgtgt gaaggcagag tacaaagatc cagctgttca aatcatcgat
    11881 gagagcggac gtgttcacat ggctcacatg gatatccact acggatacag tgttaacggg
    11941 gttgcagcac tccatactga aatcttgaaa aattctgagt tgaaagcctt ctacgacctt
    12001 tacccagaaa agttcaacaa caaaacaaac ggtatcactt tccgtcgttg gcttatgcat
    12061 gctaacccaa gattgtctca ctacttggat gagattcttg gagatggttg gcaccatgaa
    12121 gcagatgagc ttgaaaaact tttgtcttat gaagacaaag cagctgtcaa agaaaaattg
    12181 gaaagcatca aggctcacaa caaacgtaaa ttggctcgtc acttgaaaga acaccaaggt
    12241 gtggaaatca atccaaattc tatctttgat atccaaatca aacgtcttca cgagtacaaa
    12301 cgccaacaaa tgaacgcttt gtacgtgatc cacaaatacc ttgacatcaa agctggtaac
    12361 atccctgctc gtccaatcac aatcttcttt ggtggtaaag cagctccagc ctacacaatc
    12421 gctcaagaca ttatccattt aatcctttgc atgtcagaag ttattgctaa cgatccagca
    12481 gtagctccac acttgcaagt agttatggtt gaaaactaca acgttactgc agcaagtttc
    12541 cttatcccag catgtgatat ctcagaacaa atctcacttg cttctaaaga agcttcaggt
    12601 actggtaaca tgaaattcat gttgaacgga gctttgactc ttggtactat ggacggagct
    12661 aacgtggaaa tcgctgagtt ggttggtgac gaaaacatct acatctttgg tgaagattca
    12721 gaaactgtta tcgaccttta cgcaaaagca gcatataaat caagcgaatt ctacgctcgt
    12781 gaagctatca aaccattggt tgacttcatt gttagcgatg cagttcttgc agctggaaac
    12841 aaagagcgct tggaacgtct ttacaatgaa ttgatcaaca aagactggtt catgactctt
    12901 cttgacttgg aagactacat taaagtcaaa gagcaaatgc ttgctgacta cgaagaccgt
    12961 gacgcatggt tggataaagt catcgttaac atttctaaag caggattctt ctcatctgac
    13021 cgtacaatcg ctcagtataa cgaagacatc tggcacttga actaatactc ttcgaaaatc
    13081 tcttcaaacc acgtcagctt tatctgcaac ctcaaagcgg tgctttgagc aacctgcggc
    13141 tagcttccta gtttactctt tgattttcat tgagtataag atacaaattt atactaatac
    13201 attttgtaaa aaagcgaatt tcgattgaaa ttcgcttttt taatgatgta gatttgggtc
    13261 aatcttgtct aaaaataggg aaatcctaga tacagtgaag gctttaaatg ctggttttta
    13321 ctgtcctcag ccttatattt tttcgtagtt gattacctca cacctcttgt attcgcttac
    13381 ataaagtatt ataatataat tgtaggaaag aaggtgtttt tatgatatac acacttaaat
    13441 tggtgttgtt tattaccttt cttgtaataa gcttgttacc tgataagatt tttggaaaaa
    13501 ataaaaaaat ttggaaaata gtttttgcaa tattgacggc agtggcagca ttgtcattta
    13561 tgtactaagt tattttaaga atgtagggaa ataaacccta cattcttttt agttttttct
    13621 gttttctaaa ttctatttat ccaagcgctt caacatttct tgcttcttcg cttcaagttc
    13681 tgcacgcttt tcttcgattt cggcatgttt tttctcgagt tcagaataac ttgcaccatt
    13741 gctaaattct tttcgccatc aggagatagg gtgagtcgac atgtctatta ctcacccaaa
    13801 gcagtcctac aaagcaggaa ttttctgtta cttttttgga aatagtaacg tttatacagc
    13861 tttgacactt cgtatcaaag cgccaaacac actccgaggg atttacagaa agcagaaaag
    13921 gaatgatctg gtataagatc attccttttc tctctttttc tttaagtaat tatatacaat
    13981 gtacgacgaa gtcgtcattg caatgctgat ccaccaccta aagggaactt taaacaacat
    14041 tgataagata aagaatataa acaacgaaaa tacgttatac ccaattaatt ttattgtata
    14101 tctcatgatt aaaagttaat ccttccgttg ttaggaatgg catcattttt atcccataat
    14161 tgtgctaaat aagtccccgg tgataataaa ttcatagcga attctaaagc aacatcattt
    14221 acaaaccaac tacctagata tctagaaatt gctgaacgaa tagcactttt tgctgcatgt
    14281 tttcctttta ctttaattag atttgcaagg cctgcagtag ttcctcctaa tgctaaagct
    14341 attgcagtat ctaatagagc acccatttga ttaactgtaa taccttgcca agctgctcta
    14401 aatggagagt atgtaggtgg gattgtataa tcgccttgta attgtcggtt aattacttct
    14461 ttgatccatt gttgtgagac gtctggatga aaagattgga tttcgtttgc aagtgtattg
    14521 atttgttctt ctgttagaga agtgacaggt tgaagttcca tatttgtttc aatttgcgat
    14581 acttgttcag aagcgtatac agctgaaaca cttggaatcg ctgatacaat taacacaatt
    14641 gacgtcaaaa aaaccgaaat aaatttcatt aatttgttca tgagcttttc tcctttttat
    14701 ttgtatctgc ttacatttta tcatatactg ttattatagt caaaaaaata tgctattatg
    14761 ttaaaaaaat atttttcaaa atataaatgg acggatttat tttggatttt atttgttatt
    14821 ttgacctgcc tctatattgg taaccatgat ttgtttactc tcaatcatca agaattctct
    14881 tttcgtggta gcgtttgggg tctggtactg gccttatatc acttactatt cattgataag
    14941 tttgttatat cgaatcgaaa ataaagatta gagctatgct tgactgtgta cttttaggat
    15001 tgattttgga ggaagatttt gtctctatta tttattattt taaatttatt tattttgtat
    15061 aagatctatt ctttgaggcg ggaaaaatcg aaatacttga tttatacggc ctatatcata
    15121 tttggggtaa atgtagtata tggtattcaa tggttattaa aagaactgat ttcaactatt
    15181 tccccttaat gtgtatggaa actataacaa aacgcataag attaaggttt gtgtacctgt
    15241 tcttatgcgt ttttgtcata ttgaagattt tcggtaagtt ttataccttt gggaagtcta
    15301 gtttatactc aatgaaaatc aaagagtaaa ctagccgtag gttgctcaaa gtacagcttt
    15361 gaggttgcag at
//
LOCUS       DAVDFK010000043        14333 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.43, whole genome shotgun sequence.
ACCESSION   DAVDFK010000043 DAVDFK010000000
VERSION     DAVDFK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14333
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.43"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(298..1989)
                     /locus_tag="VUR04_001706"
     CDS             complement(298..1989)
                     /locus_tag="VUR04_001706"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET5341577.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2125..2571
                     /gene="argR"
                     /locus_tag="VUR04_001707"
     CDS             2125..2571
                     /gene="argR"
                     /locus_tag="VUR04_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5341578.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2622..5156
                     /gene="mutS"
                     /locus_tag="VUR04_001708"
     CDS             2622..5156
                     /gene="mutS"
                     /locus_tag="VUR04_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET5341579.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5303..6997
                     /gene="patA"
                     /locus_tag="VUR04_001709"
     CDS             5303..6997
                     /gene="patA"
                     /locus_tag="VUR04_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET5341580.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7327..7590)
                     /locus_tag="VUR04_001710"
                     /pseudo
     CDS             complement(7327..7590)
                     /locus_tag="VUR04_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7788..9554
                     /gene="patB"
                     /locus_tag="VUR04_001711"
     CDS             7788..9554
                     /gene="patB"
                     /locus_tag="VUR04_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET5341581.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9693..10382
                     /locus_tag="VUR04_001712"
     CDS             9693..10382
                     /locus_tag="VUR04_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET5341582.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10386..10565
                     /locus_tag="VUR04_001713"
     CDS             10386..10565
                     /locus_tag="VUR04_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341583.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10552..11901
                     /locus_tag="VUR04_001714"
     CDS             10552..11901
                     /locus_tag="VUR04_001714"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET5341584.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12025..13485
                     /locus_tag="VUR04_001715"
     CDS             12025..13485
                     /locus_tag="VUR04_001715"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET5341585.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13499..13933
                     /locus_tag="VUR04_001716"
     CDS             13499..13933
                     /locus_tag="VUR04_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET5341586.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
     gene            14057..14128
                     /locus_tag="VUR04_001717"
     tRNA            14057..14128
                     /locus_tag="VUR04_001717"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14090..14092,aa:Glu,seq:ttc)
BASE COUNT         4218 a         2749 c         3238 g         4128 t
ORIGIN      
        1 tatttggtta ggtgaattag tgaagtgttt aggcaagtgt ctctggttac gacgtcatgg
       61 cctctaaatc gattatattt aggggtcatg actagtgaag cagttagcta gttcgcatat
      121 aagcggctag cgtctaacaa ttaggaactt tagttccaat aactttaaga ttacgacgtt
      181 ttaggacata aatcgatcat atttatgtcc taaaactagt gaagcgccta gccaaagtcc
      241 gaataggatt tggcgttagt tacttagatt gctttgcaat caagtaactt tggcgattta
      301 catcttctct ggcgcttcta ctccaagcaa gcgaagggct tctttgagaa cgactgcggt
      361 tgcgtagctg agggctagac ggctgtcgcg ttctgggctt tcatccaaga tacgtgtatg
      421 tgcatagtat ttgttaaagg attgagccag gctaattgca aatttagcaa tgatagaagg
      481 ttcaaagtta tctgccgcac ggttgataat acgtgggaag tcttgaatga gtttaatgat
      541 ttcccagctt tcagtatcat tcaagctata gttgccagct gtttctggtt tgaaatcggc
      601 tttgcgtaag atagattgga tacgagcgta ggcatattga acgtaaggtc cagtttcacc
      661 ctcgaaggat accatagctt ctaggtcgaa gtcgtatcca tttgtacggt cggttttgag
      721 gtcatagaat ttaatggctc caaccccaac agcatgtgct acttggtctt tgttttctag
      781 ttcaggattt ttagcctcga tttggacctt ggcacggcta acagcctctg caacagtagg
      841 ctctagcaag atgacattcc ctttacgagt agagagcttc ttcccttctt ttgtaaccag
      901 accaaaagga acgtgggtaa tgtcgtcact ccaatcgtag cccatctctt gcaagacagc
      961 tttgagctgt ttaaagtggg cagattgttc ttgaccaacg acatagatag atttagcaaa
     1021 ttggtattcg tttttacggt agagggctgc agccaagtca cgtgtgatat agagagttgc
     1081 accatcagac ttcttgatga gggctggatg ttcaattcca tatttctcaa gattcacaac
     1141 ttgggcacct tctgattcaa gaagtagtcc tttttcagaa agaatgtcta caactgcatc
     1201 catcttatca ttgtagaagg cttctccgtt atagctgtca aattcaacct tcaattcatt
     1261 gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac cattgccaaa gagcgagagc
     1321 ttcctcatct ccattttcaa gtttacggaa ccattcgcgc gcttcttcat ccaagctagg
     1381 gtcattttca gcttcagcgt tgatgcggac atagagttta aggagttcat cgattggatg
     1441 agcttttaca gcttcttcgt cgccccattt tttgtaggca acaatcaaca tcccaaattg
     1501 tttaccccag tctcccaaat ggttgacctt gaccgtttga taaccgattt tttggaaaat
     1561 atgtgacaag ctatctccga taacagttga acgcaggtgg ccaatagaaa atggtttagc
     1621 gatattcgga ctagacatgt cgataacaac attttcttgt ttgccaatat tttggtcagc
     1681 atagtgttct ttttcagtgg taacagcttg caatacttga gcagaaatgg cagatttatc
     1741 aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt tcaaaggctt ggctgttcat
     1801 tttttcagcc agttcagccg caatcatttg tggtgcttta cgttcgactt ttgcaagaga
     1861 aaaagcaggg aaagcaatgt ctcccatttc tgagttttta ggggtttcca gtaactttaa
     1921 aatagcctct tggtccaggc tatcaatgat gctagataat tcgctagcaa tcaattcttt
     1981 tgtattcatt aagagctcct ttttggactt ttctactatt ttatcacaat tttaaagaaa
     2041 gaagaaaaaa tttttgaaat ctcctgtttt tttggtataa tatggttata aatatagtta
     2101 taaatatgca cgcaagagga ttttatgaga aaaagagatc gtcatcagtt aataaaaaaa
     2161 atgattactg aggagaaatt aagtacacaa aaagaaattc aagatcggtt ggaggcgcac
     2221 aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc gcgaaatcgg cttgaccaag
     2281 gtcaagaaaa atgatatggt gtattatgta ctagtaaatg agacagaaaa gattgatttg
     2341 gtggaatttt tgtctcatca tttagaaggt gttgcaagag cagagtttac cttggtgctt
     2401 cataccaaat tgggagaagc ctctgttttg gcaaatattg tagatgtaaa taaggatgaa
     2461 tggattttag gaacagttgc tggtgccaat accttattgg ttatttgtcg agatcagcac
     2521 gttgccaaac tcatggaaga tcgtttgcta gatttgatga aagataagta aggtcttggg
     2581 agttgctctc aagacttatt tttgaaaagg agagacagaa aatggcgata gaaaagctat
     2641 cacccggcat gcaacagtat gtggatatta aaaagcaata tccagatgct tttttactct
     2701 ttcggatggg tgatttttat gaattatttt atgaggatgc ggtcaatgct gcgcagattc
     2761 tggaaatttc cttaacgagt cgcaacaaga atgccgacaa tccgatccct atggcgggtg
     2821 ttccctatca ttctgcccaa cagtatatcg atgtcttgat tgagcagggt tataaggtgg
     2881 ctatcgcaga gcagatggaa gatcctaaac aagcagttgg ggttgttaaa cgagaggttg
     2941 ttcaggtcat tacgccaggg acagtggtcg atagcagtaa gccggacagt cagaataatt
     3001 ttttggtttc catagaccgc gaaggcaatc aatttggcct agcttatatg gatttggtga
     3061 cgggtgactt ttatgtgaca ggtcttttgg atttcacgct ggtttgtggg gaaatccgta
     3121 acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc tgaggaagaa gaacaaatcc
     3181 tcagccgcca gatgaatctg gtactctctt atgaaaaaga aagctttgaa gaccttcatt
     3241 tattggattt gcgattggca acggtggagc aaacggcatc tagtaagctg ctccagtatg
     3301 ttcatcggac tcagatgagg gaattgaacc acctcaaacc tgttatccgc tacgaaatta
     3361 aggatttctt gcagatggat tatgcgacca aggctagtct ggatttggtt gagaatgctc
     3421 gctcaggtaa gaaacaaggc agtcttttct ggcttttgga tgaaaccaaa acggctatgg
     3481 ggatgcgtct cttgcgttct tggattcatc gccccttgat tgataaggaa cgaatcgtcc
     3541 aacgtcaaga agtagtgcag gtctttctcg accatttctt tgagcgtagt gacttgacag
     3601 acagtctcaa gggtgtttat gacattgagc gcttggctag tcgtgtttct tttggcaaaa
     3661 ccaatccaaa ggatctcttg cagttggcga ctaccttgtc tagtgtgcca cggattcgtg
     3721 cgattttaga agggatggag caacctgctc tagcctatct catcgcacaa ctggatgcaa
     3781 tccctgagtt ggagagtttg attagcgcag cgattgctcc tgaagctcct catgtgatta
     3841 cagatggggg aattatccgg actggatttg atgagacttt agacaagtat cgttgcgttc
     3901 tcagagaagg gactagctgg attgctgaga ttgaggctaa ggagcgagaa aactctggta
     3961 tcagcacgct caagattgac tacaataaaa aggatggcta ctattttcat gtgaccaatt
     4021 cgcaactggg aaatgtgcca gcccactttt tccgcaaggc gacgctgaaa aactcagaac
     4081 gctttggaac cgaagaatta gcccgtatcg agggagatat gcttgaggcg cgtgagaagt
     4141 cagccaacct cgaatacgaa atatttatgc gcattcgtga agaggtcggc aagtacatcc
     4201 agcgtttaca agctctagcc caaggaattg cgacggttga tgtcttacag agtctggcgg
     4261 ttgtggctga aacccagcat ttgattcgac ctgagtttgg tgacgattca caaattgata
     4321 tccggaaagg gcgccatgct gtcgttgaaa aggttatggg ggctcagacc tatattccaa
     4381 atacgattca gatggcagaa gataccagta ttcaactggt tacagggcca aacatgagtg
     4441 ggaagtctac ctatatgcgt cagttagcca tgacggcggt tatggcccag ctgggttcct
     4501 atgttcctgc tgaaagcgcc catttaccga tttttgatgc gatttttacc cgtatcggag
     4561 cagcagatga cttggtttcg ggtcagtcaa cctttatggt ggagatgatg gaggccaata
     4621 atgccatttc gcatgcgacc aagaactctc tcattctctt tgatgaattg ggacgtggaa
     4681 ctgcaactta tgacgggatg gctcttgctc agtccatcat cgaatatatc catgagcaca
     4741 tcggagctaa gaccctcttt gcgacccact accatgagtt gactagtctg gagtctagtt
     4801 tacaacactt ggtcaatgtc cacgtggcaa ctttggagca ggatgggcag gtcaccttcc
     4861 ttcacaagat tgaaccggga ccagctgata aatcctacgg tatccatgtt gccaagattg
     4921 ctggcttgcc agcagacctt ttagcaaggg cggataagat tttgactcag ctagagaatc
     4981 aaggaacaga gagtcctcct cccatgagac aaactagtgc tgtcactgaa cagatttcac
     5041 tctttgatag ggcagaagag catcctatcc tagcagaatt agctaaactg gatgtgtata
     5101 atatgacacc tatgcaggtt atgaatgtct tagtagagtt aaaacagaaa ctataaaacc
     5161 aagactcact agttaatcta gctgtatcaa ggagacttct ttgacaattc tccacttttt
     5221 tgctagaata acatcacaca aacagaatga aaaggagctg acgcattgtc gctccctttt
     5281 gtctattttt taaggagaaa gtatgctgat tcagaaaata aaaacctaca agtggcaggc
     5341 cttggcttcg ctcttgatga caggcttgat ggttgctagt tcacttctgc aaccgcgtta
     5401 tctgcaggaa gtattagacg ccctccttac tgggaaatat gaagctattt atagtatcgg
     5461 ggcttggttg attggtgtgg ccgtagtcgg tctagttgct ggtggactca atgttgtcct
     5521 cgcagcctat attgcccaag gagtttcatc cgaccttcgg gaggatgcct tccgtaaaat
     5581 tcaaaccttt tcttatgctg atattgaaca atttaatgcg ggaaatctag tcgttcgaat
     5641 gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg accttccaaa ttcttttcag
     5701 acttcccctc ttgttcatcg gttcgtttat cctagcggtt caaaccttac cttctctgtg
     5761 gtgggtgatt gttctcatgg tagtcttgat ttttggtttg actgctgtca tgatgggaat
     5821 gatggggcct cgttttgcca agtttcaaac ccttcttgag cgcatcaatg ccattgccaa
     5881 ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc caagaaaaag agcaatttgc
     5941 taagtttaca gaggtctcag acgagctttt tggtcaaaac ctttacattg gttatgcctt
     6001 ttcagtagtg gaacccttta tgatgttggt tggttacggg gcggtcttcc tctctatttg
     6061 gctggtcgcg ggaatggttc agtcggatcc gtctgttgtt ggttccatcg cttcttttgt
     6121 taattaccta agccagatta tctttaccat tgttatggtt ggatttttgg gaaattctgt
     6181 cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt cttgatgcag agccagctat
     6241 gaccttcaag gatatcccag atgaagagtt ggttggaagc cttagctttg aaaatgtgac
     6301 ctttacctat ccaatggaca aggaaccgat gctgaaagat gtgagcttta ctattgaacc
     6361 tggtcaaatg gttggtgtag ttggagcgac tggtgcagga aagtcaacct tggctcaatt
     6421 gattccacgt ctctttgatc cacagaacgg ggccattaaa atcggtggca aggatattcg
     6481 agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc gttctccaac gtgccattct
     6541 ttttagtgga acgattgcag ataacttgag acaggggaag ggaaatgcta ctctatttga
     6601 aatggagcgc gcagccaata ttgcccaggc tagtgaattc attcatcgta tggagaaaac
     6661 ctttgaaagt ccagttgaag aacggggaac caatttctct ggtggacaaa aacaaaggat
     6721 gtcgattgcg cgtgggattg tcagcaatcc acgtattctg atttttgatg attcgacctc
     6781 agccttggat gccaaatcag agcgcttggt gcaagaagct ttgaataagg acttgaaggg
     6841 tacgacaacc attattattg ctcaaaaaat tagctcggtt gtccatgcag acaagatctt
     6901 ggttctaaat caaggacgat tgattggtca aggcacgcat gcagacttgg ttgccaacaa
     6961 tgccgtttac cgtgaaatct atgaaacaca gaaatgaaag acaaactata agaaaagtca
     7021 atagttttat ctaaactatt tcttatttca atttgatgat ttggcgatga ttttagagaa
     7081 cggcaaaaag cccttgaaaa agtccatttt ttcaaaggta atcctgtgtt gatttcagaa
     7141 attacatcac tttttgttcg tcaaatggca gctctttttt aggatataaa acagggttcg
     7201 gataagtttt tttgcaaggt ggatgatggc tacattgtaa tgttttcctt attctaactt
     7261 agtcttaaga taggtcttga aagcaggtga aaagcgaggg catgctttgg cagcttgtat
     7321 gagtacctac cgcagatgag gggaaccccg tttgaccatt cttccagcta aatcaatctg
     7381 acctgactga taaatagaag aatccagtcc agcgaaagct tgtaattgag caagattatc
     7441 aaaggcatga atatttcgaa tctcggctaa aatgaccgcc cctaaacgat tcccaatccc
     7501 agtaaccgtc gtgatgatcg agttgaactc agccatcaag tcattgacac atgtttccgc
     7561 cttgtcaatg agcctcttgt aatgtttgat gttttcatta cacgagataa aacgtttatg
     7621 cgttatcaaa ctcatgacca attgaaacga aaagctgtgg ttagatcctt tcggaaattg
     7681 tcaagcgatt ggaggaaatg aactaatcca cagcggctta ttccaagtat accacttggg
     7741 ctttggcagt agctaactgc gctaaatata atataaggag gagtaaaatg aagacagttc
     7801 aatttttttg gcattatttt aaggtttaca agttctcatt tgtagttgtc atcctgatga
     7861 ttgttctggc gacttttgcc caagccctct ttccagtctt ttctggacaa gcggtgacgc
     7921 agctagccaa tttagttcaa gcttatcaaa atggcaatcc agaacttgta tggcaaagcc
     7981 tatcaggaat catggtcaat cttggcctgc tggttttggt tctatttatc tctagtgtaa
     8041 tatacatgtg tctcatgacg cgcgtgattg cagaatcgac caacgagatg cgcaaaggcc
     8101 tctttggtaa gcttgctcag ttgacggttt ctttctttga ccgtcgacaa gatggcgata
     8161 tcctgtctca ttttaccagt gatttggata atatcctaca agcctttaac gaaagcttga
     8221 ttcaggtcat gagcaatatt gttttataca ttggtctgat tcttgtcatg ttttcgagaa
     8281 atgtgacgct ggctctcatc accattgcca gcaccccatt ggctttcctt atgctgattt
     8341 tcatcgtgaa aatggcacgc aaatacacca acctccagca gaaagaggta gggaagctca
     8401 acgcctatat ggatgagagc atctcaggcc aaaaagccgt gattgtgcaa ggaattcaag
     8461 aggatatgat ggcaggattt cttgaacaaa atgagcgcgt gcgcaaggca acctttaaag
     8521 gaagaatgtt ctcaggaatt cttttccctg tcatgaatgg gatgagcctg attaatacag
     8581 ccatcgtcat ctttgctggt tcggctgtac ttttgaatga taagtctatt gaaacaagta
     8641 cagccctagg tttgattgtt atgtttgcac aattttcaca gcagtactac cagcctatta
     8701 tccaagttgc agcgagttgg ggaagccttc agttggcctt tactggagct gaacgaattc
     8761 aggaaatgtt tgatgcagag gaggaaatcc gacctgaaaa ggctccaacc ttcactaagt
     8821 tgcaagaaag tgttgaaatc agtcatatcg atttttcata cttgcctgat aaacctattt
     8881 tgaaagatgt cagcatttct gcccctaaag gccagatgac agcagttgtt gggccgacag
     8941 gttcaggaaa aacgactatt atgaacctca tcaatcgctt ttatgatgtt gatgctggtg
     9001 gtatttattt tgatggtaaa gacattcgtg gctatgactt agatagtctt agaagcaagg
     9061 tgggaattgt attgcaagat tcggtcttgt ttagcggaac gattcgagac aatatccgat
     9121 ttggtgtgcc agatgctagt caggaaatgg ttgaggtagc agcaaaagca acccacattc
     9181 acgactatat cgaaagtttg cctgataagt acgatactct tattgatgat gaccagagca
     9241 tcttttcaac agggcagaag caattgattt caatcgctcg aaccctgatg acagatccag
     9301 aagttctcat tctcgatgaa gcaacttcaa acgtagatac ggtgacagaa agcaagattc
     9361 agcatgccat ggaggtggtt gtagcaggta gaactagttt cgtcattgcc caccgcttga
     9421 aaaccattct caatgcagat cagattattg tccttaaaga tggagaagtc attgaacgtg
     9481 gtaaccacca tgaacttttg aagctaggtg gcttttattc agaactctat cacaatcaat
     9541 ttgttttcga ataagaaaga agttgtccta tgtgggcagc tttttcttgt ccataaaaaa
     9601 tgtttatcac agccttaaaa aaaacatatt agacgaaagt cattttgagt gatatgatag
     9661 gactatcgtt agcattcgaa aggagaggca tcatggctag aacggttgta ggagttgctg
     9721 caaatctatg tcccgtagac gcagaaggta aaatcattca ttcatctgta tcttgtagat
     9781 tcgcagagat cattcgtcaa gtcggtggtc tccctttagt cattcctgtt ggtgatgagt
     9841 cagttgtacg tgattatgtg gaaatgattg acaaactcat tttgacagga ggccaaaatg
     9901 ttcatcctca gttttatgga gagaaaaaga ccgtcgagag cgatgattac aatctggtcc
     9961 gtgacgaatt tgaattggca ctcttgaagg aagcgcttcg tcagaataaa ccaattatgg
    10021 caatctgtcg cggtgtccaa cttgtcaatg ttgcctttgg tggaaccctc aatcaagaaa
    10081 tcgaaggtca ctggcaagga ctacctttcg ggacatctca ctctattgag acagtagaag
    10141 gaagcgtggt ggctaagcta tttgggaaag aaagtcaggt caattcagtc catcgtcaaa
    10201 gcattaaaga tttggcaccc aatttccgtg taactgctat tgattcaaga gaccaaacta
    10261 ttgaagcgat tgagtctatc gacgagcacc gcattatcgg tttacagtgg catccagagt
    10321 ttctggttaa tgaagaagat ggcaatttag aattatttga gtatttattg aatgaactgt
    10381 aacgattgga acatctggtc gttctttctt ttattttttc aaaattttta gaatgtggca
    10441 ttttacgcaa acgtttgaat tctgataaaa attggagaaa ttcgacaaaa aaacttgaaa
    10501 aaaacgaagg taagcgttat gatagaaaag aagaaatatt ggaggaagaa catgtcacat
    10561 attaaatttg attattcaaa agttttagac aaatttgttg caccacatga agtggaatac
    10621 atgcaatcac aagtaacagc agcagatgaa ttgatccgta aaggaactgg tgctggtagc
    10681 gacttcttgg gatggttgga ccttcctgaa aaatacgatc gcgaagaatt tgaccgcatc
    10741 ttgaaagctg ctgagcaaat caagtcagac agcgatgttt tggttgtgat cggtattggt
    10801 ggatcttacc ttggtgcaaa agcagcaatc gacttcttga atcaccattt tgctaacttg
    10861 caaacaaaag aagaacgcaa agctccacaa atcctttacg caggaaactc aatctcatct
    10921 acttaccttg ctgacttggt agagtatgtt gcagacaaag acttctcagt aaacgtaatt
    10981 tctaaatcag gtacaacaac tgaaccagcg attgctttcc gtgtctttaa agaactcttg
    11041 gttaagaaat acggacaaga agaagctaac aaacgtatct atgcaacaac tgaccgccaa
    11101 aagggtgctg ttaaggttga agcagacgct aacggttggg gaacatttgt tgttccagat
    11161 gatatcggtg gacgcttctc agtattgaca gccgttggtt tgcttccaat cgcagcatca
    11221 ggagctgaca tcaaagctct tatggaaggt gcgaatgcag ctcgcaaaga ctacacttca
    11281 gacaaaatct ctgaaaacga agcttaccaa tacgcagtcg ttcgtaacat cctttatcgt
    11341 aaaggctatg caactgagat cttggtaaac tatgagccat cacttcaata cttctcagaa
    11401 tggtggaaac aattggctgg tgaatcagaa ggaaaagacc aaaaaggtat ctacccaact
    11461 tcagccaact tctcaactga cttgcactca cttggtcaat ttatccaaga aggaactcgt
    11521 atcatgtttg aaacagttgt ccgtgttgac aaacctcgta aaaacgtgct tattcctact
    11581 ttggaagaag accttgacgg acttggttac cttcaaggaa aagacgttga ctttgtaaac
    11641 aaaaaagcaa ctgacggtgt tcttcttgcc cacacagatg gtgatgtacc aaacatgtat
    11701 gtgactcttc cagagcaaga cgctttcact cttggttaca ctatctactt cttcgaattg
    11761 gcaattgccc tttcaggtta cttgaatgct atcaacccat ttgaccaacc aggtgttgaa
    11821 gcttataaac gtaacatgtt tgcccttctt ggaaaaccag gatttgaaga attgagcaaa
    11881 gaacttaacg cacgtctata atagaagaaa agagtggttt gcccactctt tttactctct
    11941 ttatccatag aaattggact cagccaagac ttgtgatata atatagaaag caaaaaggca
    12001 gacgcctaga taataggaga aactatgtca aaagatatcc gcgtacgtta cgcaccaagt
    12061 ccaacaggac tactacacat cggaaatgct cgtacagcat tgtttaatta cttgtatgcg
    12121 cgccatcatg gtggaacatt tctcatccgt atcgaagata ctgaccgtaa acgccatgtc
    12181 gaggatggtg aacgttcaca acttgaaaac cttcgctggt taggcatgga ttgggatgaa
    12241 agtccagaat cacatgagaa ttatcgccag tctgagcgtt tggacttgta tcaaaaatac
    12301 attgaccaac tattagctga aggaaaagcc tataaatctt acgttacaga agaagagttg
    12361 gcagctgaac gcgaacgcca agaagtagct ggcgaaacac cacgctacat caatgaatac
    12421 cttggtatga gtgaagaaga aaaagcagct tacatcgcag aacgtgaagc agcagggatc
    12481 atcccaactg ttcgtttggc tgtcaatgag tcaggtatct acaagtggca tgatatggtc
    12541 aaaggcgata tcgaatttga aggtggcaat atcggtggtg actgggttat ccaaaagaaa
    12601 gacggttacc caacttacaa ctttgccgtt gttatcgatg accacgatat gcaaatctct
    12661 catgttatcc gtggagatga ccatattgct aatacaccaa aacagcttat ggtctatgaa
    12721 gctcttggtt gggaagctcc agagttcggt cacatgacct tgattatcaa ctctgagact
    12781 ggtaagaagt tatctaaacg tgatactaat acacttcaat ttatcgaaga ttaccgaaag
    12841 aaaggttacc ttccagaagc agtctttaac tttattgctc ttcttggttg gaacccaggt
    12901 ggtgaagatg agattttctc tcgtgaagaa ctcattaaac tttttgatga aaaccgcctc
    12961 agcaagtcac cagcagcctt tgatcagaaa aaactagact ggatgagcaa tgattatatc
    13021 aagaatgcag accttgaaac catctttgaa atggcaaaac cattcttaga ggaagcaggc
    13081 cgtttgactg acaaggctga aaaattagtt gagctctata aaccacaaat gaaatcagta
    13141 gatgagatta tcccattgac agatcttttc ttctcagatt tcccagaatt gacagaagca
    13201 gagcgcgaag tcatgacggg tgaaacagtt ccaacagttc ttgaagcatt caaagcaaaa
    13261 cttgaagcga tgacagatga taaatttgtg acagaaaata tcttcccaca aattaaagca
    13321 gttcaaaaag aaacaggtat taaagggaaa aatcttttca tgcctattcg tatcgcagtt
    13381 tcaggcgaaa tgcatgggcc agaattacca gatacaattt tcttgcttgg acgtgaaaaa
    13441 tcaattcagc atatcgaaaa catgctaaaa gaaatctcta aataaagagg atacaataat
    13501 ggacatctgg gaaaagatgt acgaagaagc acagaaacta tacaatccac atgaagtatc
    13561 agactttgtt tatgccaatc atgttgtagc tgcagtagaa gcagaagatg gacaaatatt
    13621 tacaggattc tgtatggagg gaacctgtgg tgttttccat ctctgcgcag aacgggcggc
    13681 cctcttcaat atgtaccaat tttcaggaca aactaaggtt aagaaagtat tagcctttcg
    13741 agacaaacca ccttatggtg gaagttcagc catgccttgc ggtgcttgta gagaattcct
    13801 tttagagctt aatgctgaaa ataaagatgc agaattcatg atggactata atataagaaa
    13861 aacagttaaa gtcgcagaac taatccctta ttggtgggga gaagaacgtg cttctaagtt
    13921 taatgagcga tagaagagtc agtataattc tggctttttt tactataagt tgcaaaaaaa
    13981 atgaaaaaaa ttagaaaaag tagttgacaa agtttgaaaa gactgtataa tagtaagagt
    14041 tgaaaataac aactcaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt
    14101 aacacgggtt cgaatcccgt acggactatg gtatgttgcg gttggaacac ttgatgaaaa
    14161 aaagtttaaa aaagcttaaa aatcttcaaa aaagtgttga caagcgaaag cggctgtgat
    14221 atactaatat agttgtcgct tgagagaagc aagtgacaaa gacctttgaa aactgaacaa
    14281 gacgaaccaa tgtgcagggc gctacaacat aagttgtagt actgaacaat gaa
//
LOCUS       DAVDFK010000044        13846 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.44, whole genome shotgun sequence.
ACCESSION   DAVDFK010000044 DAVDFK010000000
VERSION     DAVDFK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.44"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(105..542)
                     /locus_tag="VUR04_001718"
     CDS             complement(105..542)
                     /locus_tag="VUR04_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET5341587.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(627..3260)
                     /gene="polA"
                     /locus_tag="VUR04_001719"
     CDS             complement(627..3260)
                     /gene="polA"
                     /locus_tag="VUR04_001719"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET5341588.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKNAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYLQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3511..3861
                     /locus_tag="VUR04_001720"
     CDS             3511..3861
                     /locus_tag="VUR04_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET5341589.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4076..4192
                     /locus_tag="VUR04_001721"
     CDS             4076..4192
                     /locus_tag="VUR04_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET5341590.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4185..4436
                     /locus_tag="VUR04_001722"
     CDS             4185..4436
                     /locus_tag="VUR04_001722"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341591.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGLSVSEFEPFCVEKSPI"
     gene            4480..4758
                     /locus_tag="VUR04_001723"
                     /pseudo
     CDS             4480..4758
                     /locus_tag="VUR04_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4895..5863)
                     /locus_tag="VUR04_001724"
     CDS             complement(4895..5863)
                     /locus_tag="VUR04_001724"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET5341592.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6008..6550)
                     /locus_tag="VUR04_001725"
     CDS             complement(6008..6550)
                     /locus_tag="VUR04_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET5341593.1"
                     /translation="MDQLLGVLFPDSTFLNAFESAIVAPLVEEPLKLLPLVFVLALIP
                     VRKLKSLFLLGIASGLGFQMIEDIGYIRTDLPEGFDFTISRILERIISGIASHWTFSG
                     LAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAIPVVTAI
                     ALYGFYHAYCFVEKHNELMT"
     gene            complement(6554..6838)
                     /locus_tag="VUR04_001726"
     CDS             complement(6554..6838)
                     /locus_tag="VUR04_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341594.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFLALFYM
                     IPALYFLFHIGKKWELPKKVLILSLLGAICSFTSLLLFGIYNHRRKSSKV"
     gene            complement(6863..7360)
                     /locus_tag="VUR04_001727"
     CDS             complement(6863..7360)
                     /locus_tag="VUR04_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET5341595.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7433..8794)
                     /gene="radA"
                     /locus_tag="VUR04_001728"
     CDS             complement(7433..8794)
                     /gene="radA"
                     /locus_tag="VUR04_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET5341596.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8808..9323)
                     /locus_tag="VUR04_001729"
     CDS             complement(8808..9323)
                     /locus_tag="VUR04_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5341597.1"
                     /translation="MKIIFVRHGEPDYRELEERFYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9325..9768)
                     /locus_tag="VUR04_001730"
     CDS             complement(9325..9768)
                     /locus_tag="VUR04_001730"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET5341598.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9828..9921)
                     /gene="ffs"
                     /locus_tag="VUR04_001731"
     ncRNA           complement(9828..9921)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VUR04_001731"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(9954..10421)
                     /locus_tag="VUR04_001732"
     CDS             complement(9954..10421)
                     /locus_tag="VUR04_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET5341599.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(10622..11908)
                     /locus_tag="VUR04_001733"
     CDS             complement(10622..11908)
                     /locus_tag="VUR04_001733"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET5341600.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(12139..12375)
                     /locus_tag="VUR04_001734"
     CDS             complement(12139..12375)
                     /locus_tag="VUR04_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET5341601.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            12635..13363
                     /locus_tag="VUR04_001735"
                     /pseudo
     CDS             12635..13363
                     /locus_tag="VUR04_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13398..13607)
                     /locus_tag="VUR04_001736"
                     /pseudo
     CDS             complement(13398..13607)
                     /locus_tag="VUR04_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13773..13846)
                     /locus_tag="VUR04_001737"
     tRNA            complement(13773..13846)
                     /locus_tag="VUR04_001737"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13810..13812),aa:Asn,seq:gtt)
BASE COUNT         4370 a         3303 c         2328 g         3845 t
ORIGIN      
        1 caacctcaaa acagtgtttt gagcaacccg cagctagttt cctagtttgc tctttgattt
       61 tcattgagta taacacaaaa ggtagcccat cagctacctt tttcttatgc ttcctcaatc
      121 aagcgagtat gttctctctt gatacagcga ttcatcacga tatcatcaca tccaccatca
      181 cgcaaaatct ctttcgcttc taaactttca agtcctagct gtgcccaaaa aatcttggca
      241 tcagctttga gaaaatcacg cgccacatcg ggcagaaatt cactgcgacg ataaacattg
      301 acaatatcta caggaaaagg aatttcagcg aggctagcat aagccttttc acccaagatt
      361 tcgccacctg ccgccttggg attgactggg atgattttat agccccgagc ctgcatttcc
      421 tttgttactc gattactggt tgtttcttca cggtcagaca aacccaccac agcaagggtt
      481 ttactcgttg cgagatactg acgaatcacg ccatcacttg gattgataaa ttcttgactc
      541 atagaaatcc tcctttttca tcagtatagc acattttgaa aaggtttgca gaattctact
      601 acaaaaaagg aggactagcc ccctttttat ttagcctcgt accaggttgc cccttcattc
      661 tcatctgcga taagaggaac actgagttga atggcttctt ccatggtttg tttcaccaat
      721 tttttcatct ctaccaattc agatttaggc acttcaagga cgatttcatc gtgcacttgt
      781 aacagcatct tggtctgata accacctgca accaaggctt tatccagctg aatcatggca
      841 atcttgagaa tatctgctgc cgaaccctgg ataggtgagt tgatagcagt tcgctccgca
      901 aaaccacgaa tattgaagtt gcgcgaattg atatctggca actcacggcg acgcttaaag
      961 agggtctcta catagctctt atcacgcgcc tcccgcacca cttcatccat gtagttttta
     1021 atacctggaa aacgttcaaa gtaggtatca atgtaggctt tggcttcctt acgactaatt
     1081 cccaaattat tagacaagcc aaagtctgaa atcccataaa ccactccaaa gttaactgcc
     1141 ttggcattgc gacgatcatt tgcagtcaca ttatcaggac gctcaatgcc aaagacccgc
     1201 atggctgtcg aagtatggat atctgccccc tcttggaagg ccttaatcaa gtgctcatcc
     1261 ttagaaatat gcgccaaaac gcgcaattca atctgtgaat agtcagagct gagtagcaca
     1321 ctatcctccc actctggcac aaaagccttc cgaatcaagc gcccctgttc caatcgggca
     1381 ggaatatttt gcaagtttgg atccacacta gacaaacgcc cggtctgggt caaatcctgc
     1441 aaatagcgag tatgaatctt tccatcagcc aaaatccagt cctgcaagcc aattacataa
     1501 gtagattgaa tcttagcaat ttgacggtaa tccaggattt tcttaacaat cggagcaata
     1561 ggagcgagac gctccaaaac atccactgct gtcgaataac ctgtcttggt tttcttagtg
     1621 tattctagag gaagtcccaa tttctcaaag agaagcacgc ccaactgctt aggcgagttg
     1681 acattaaact cctcaccagc cagctcgtaa atctcttgag tcagtttttc aatgacaagc
     1741 tcattttcag cctgcatctc aagcaaggtc tctttcttga ccataatccc agcaatttcc
     1801 atcttggcaa ggacaaaagc cagaggttgc tccatatcat aaagaagctc taattgccca
     1861 ttttcgctga gtttttcaag taaaataggc tctgtttcta ccaaaacagc aagtttacaa
     1921 gctaagtgtt ccaagaattt ctcacgttca ggaatggcat ttttaacacc cttaccgtag
     1981 aaagtttcat catcaaccaa gtaagtctga ccataaagac tagcgatggt cgcaatttca
     2041 ttgtcctcca cagtcgaaag gaggtattta gccaaacgga tgtcaaaagc aggcgcctgc
     2101 aaatccacac caaaacgttg caaaagaact ttaaccttct taaagtcata aactctcaga
     2161 gatgtttttt ctaagaaatc cttgaaaatc gggtcttgca acagctcaag cttgtctgtg
     2221 gcatagagct tatccccaca agaccaggca aatccaacca aattatccgt atggtaattc
     2281 tcaccaaaaa gctcaaagtg gaagatagac tcttcactca gcatatcttg actgatttgg
     2341 tcaacaatag taaaatccaa actctcagac acatcagctg acgacacatt taaagcctgc
     2401 ttgagctgtt tgaagcccat ctcatcgtag aatttcccaa gattttcaac atctggacca
     2461 ctatagacca agtcctctaa accaatcgca atcggtgcct tggtatcaat ggtcgctagt
     2521 gttttagaca aaaaggcctg ttccttgtca ttgatgagat tttccttcat cttagaagtc
     2581 ttcattccat caatattttc ataaatcccc tcaagcgaac catgctccag caagagctta
     2641 atacccgtct tttcaccgac tttggtcacc ccagggatat tatccgactt atcacccatg
     2701 agcgccttga gatcgataaa ctgagctggt gtgaggccca tttcttccat gaggtaatct
     2761 ggcgtaaagg cctcaaactc agccacacct ttcttggaaa tttcaaccac cgtatgctca
     2821 tccgtcagct gaatcaaatc cttgtcccca ctgacaatgg taatatcaaa accatcctgc
     2881 tctgctagct tatccagcgt cccaatgatg tcatccgcct catactgagc cagctcatag
     2941 tgacgaatcc ccatatgatc cagcaactca cgaatgaaag gaaattgctc acgaaactca
     3001 tcaggagtct tggcccgacc acccttatag tccgcataca tctctgtccg gaaggtcgtc
     3061 tttcccgcat caaaagccac caaaatatga ctcggctcaa cccgctccaa caaatgactc
     3121 aacatcaact gaaaaccata aatcgcattg gtatgcaaac cagccgcatt cttaaaacgg
     3181 tccaactgct gatacagcgc aaaaaacgcc cgaaaagcta cagaagaccc atcaatcaat
     3241 aataattttt tcttatccat acacccatta taaaggaaag aatcaaaaaa taccattggg
     3301 aagagctaga gcaagtattt ttcaaacttt ttccgaataa atagatagag ccagagaatt
     3361 tagtaaacct agatttaaaa atgtgctata atatattgaa tctataatag tacaccttga
     3421 ctgctaaaat atttctataa attaatttga ctttcctgat agagttattc acatcttatt
     3481 tcaactcact atagaaggag gaataggagg attctcagac atccgggcat cagcccaact
     3541 aatgatttga ttgctaagaa aatattcagc aatccagaaa tcacttgtca atttattcgc
     3601 gatatgctgg acttgccagc aaaaaatgtg accattttgg agggaagcga tattcacgta
     3661 ttactctcca tgccttactc ggtgcaggat ttttatacca gtatagacgt cttggcggag
     3721 ttggataacg gtactcaagt aattattgag attcaagtcc atcatcagaa ttttttcatc
     3781 aatcacttgt ggacttacct gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag
     3841 cgagaaggtg atactcacta gagctacaaa cacatcgctc ctgtttacgc cattgctatc
     3901 gtggatagta attatttctc agatgacctg gcttttcata gctttagtat gcgcgaagac
     3961 acaacaggtg aggtattggc gattaccaac aatggacagg aaaaccatct ggttaagatg
     4021 gcattcttgg aattaaaaaa tacagagaaa ccagcaagga cgaggttcgc aagccatggt
     4081 tggagttttt cggcaacaag ccctttaccc agcaaccgca acgagccatt acccaagcaa
     4141 atcaactgct ggactacaag agctggtccg aggaggacag gaaaatgttt agtcaactac
     4201 atatgcgaga agaacaagtc ttgttagcac aggactatgc cttggaaact gctagggctg
     4261 aaggccttga acaaggacta gagcgtggga aagttgaagg aagggcagaa aggaaacttt
     4321 ttgccttcct agacatagta cgccaaggtc ttctgacttc tgaggttgcc agccagcaat
     4381 taggtctgtc agtatctgaa tttgagccat tttgtgtaga aaaaagtccc atataaccta
     4441 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
     4501 acaaaattac tagacattaa agaccctaat gtccagattt taaacatcat caataaggat
     4561 acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc tgagtgcgga
     4621 aaccaattga agaaatatga ctttcaaaaa ccttctaaaa ttccttatct tgaaacgact
     4681 ggtataccta ctagaattct ccttagaaag cgtcgattca agtgctatca ctgttcaaaa
     4741 atgatggtcg ctgaaactta tgatgacgta cagtcatatt tcttctcttt ttattatatc
     4801 acagttttaa atctagcttt actagattca ccgctactat ctatttattc ggaaaaaaga
     4861 cgaaaaaacc tgagaatcat ctcaggcttg gtcattaaat ttttttctca atatcgaaaa
     4921 gtggagaaag tggtcgtttt tcatgaatac gtacgatagc atcccctagg agatgagcga
     4981 ttgaaatctg ctcaatctta tcaatcaaac gctcttctgg cagatagatg gtatccaaaa
     5041 caaccaattt cttaatagct gatttttgga tattgtccgt agcaggacca gaaagaactg
     5101 ggtgcgtaca gcttgcatag acttcaacag caccagcttc cgcaagagca tctgccgcat
     5161 gacaaatcgt tccagcggta tcaatcatat catcaatcaa gatacaagtc ttgccttcaa
     5221 ccttaccgat gatgttcata acttcactag tattcatctt atcaacgcta cgacgtttat
     5281 caataatagc gatagatgtt ttcaaaaatt ctgccaactt acgagcacga gtcacccctc
     5341 catggtccgg gctgacaacc acatagtcag aaccaaccat accacgacgc tcaaaataat
     5401 ctgcaatcag aggagcaccc atcaaatgat ccacaggaat atcaaagaat ccttgaattt
     5461 gcgcagcatg caagtcgatg gtcaataaac gatccactcc agctacttca agcatatttg
     5521 cgacaagttt tgaagtgatt ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc
     5581 catagtaagg catgacaaca ttgacagatt ctgcactcgc acgcttcaaa gcatctacca
     5641 taatcaaaat ttcaagcaga ttgtcattta caggcgaact agttgattgt aagataaaga
     5701 cgtgtttccc acggattgat tcttcaatgt tgacctgaat ctctccatct gaaaattggc
     5761 gaacacttga tttccccaac tctatcccaa tctcctgcgc cacacgttct gccaattctt
     5821 tattagaaga aagggcaaac agctttaaat cagaaaaaga catgatttcc tccggtatat
     5881 atgtataact tgtgcttttc acaagatttt ccatctacca ttgtagcgct ttttgcacta
     5941 tttttcaatc aaaaataaaa gaagggcacc atatttgtac ccttgcatca ttcttttgaa
     6001 aaatattcta ggtcatcaac tcattgtgtt tctcaacaaa gcaataagca tgataaaaac
     6061 catagagagc aatagccgta accactggaa tcgctaaagg caactctgtt tccaactcca
     6121 caaaaggaga gttaaacaag aagtgagttc ccaaggctaa acctagaaaa ataaggccct
     6181 gtttcttgcc aaccttctgt cctttatagg ctctgtaaag caagtaaaca cctactacag
     6241 ctagacctga aaaagtccag tgagaggcaa ttcctgagat gatacgctct aaaattcgcg
     6301 aaatagtaaa gtcaaagccc tctggcaaat ccgtacgaat ataaccaata tcctcaatca
     6361 tttggaatcc caaaccggaa gcaattccaa gtaaaaacaa agattttaat tttcgcacag
     6421 gaatcaaagc caaaacaaaa acaagtggca ataatttcaa gggttcttct accaaaggag
     6481 ccacaatagc actttcaaag gcatttaaaa atgtactatc tgggaaaaga acccccagta
     6541 actggtcgat tttttatacc ttagatgact ttcgtctgtg attatagatt ccaaatagta
     6601 agagagaagt aaaggaacag attgctccca ataaagacag aatcaaaacc ttctttggca
     6661 attcccattt tttcccaata tggaagagaa aataaagagc cggaatcatg taaaagagag
     6721 ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa ccgtccgtat
     6781 agtagatggt ttcatactgt aaaccaatac atagcaataa aatactgctt ttcttcatac
     6841 actttctttc taaatgaagt atttataatt ctacgactgt catacttcct gtatcaacat
     6901 tgtaaatagc accagagata atgacatcgt ctggtattag gggagactcg ataagcagtt
     6961 gcatatcctc gcgtacactc tcttctatat cttggaaggg caagaagtcc tggtctgaca
     7021 catctacacc taattcctct tttaaatact cctgaaaagg ttcattttca aaggtctgag
     7081 caccacagtc tgtatggtgc aataccacaa tctctcttgt ccccatttgt tgctgggaaa
     7141 taactagcga acgaatcatg tcttcagtca ctcgaccacc tgcattccgc aagatatgag
     7201 catctccaag tgccaagccc agagcttgcg caacgtgcag acgagagtcc atacaggtca
     7261 caatagctac tcttgttttg ggtttaagtg gcagatttaa ctgcccatgt agggcaacat
     7321 aagcctgatt agcttgcata aactgttcaa aatacgacac gattccctcc ttgaaaattt
     7381 gatagtcaaa tatttctcct atcttatcat ttttaagaga atttgtcacg gattatgcaa
     7441 agaccttttt caaaacttcc tgaatcgttg tcacgccaat gacctgaatt tccttaggca
     7501 gagtgattcc tgtcaaggaa ttcttaggta cataaatctt agtaaagccc agtttagcag
     7561 cttcgttgat gcgttgctca atacgattca cgcgccgaat ctctcctgtc aagcccagtt
     7621 ctccgacaaa acattcctga ggattagttg gcttgtcttt gtagctcgaa gcaatagcaa
     7681 ctgcaacagc caagtcaatg gcaggttcat ccaatttaac accaccagca gatttgagat
     7741 aggcatcctg attttgcaag agaagccctg cccgtttttc caaaacagcc ataatcaagc
     7801 tagcacggtt aaaatcaagt cctgtcgtag tacgcttggc atttccaaac atggtcggtg
     7861 ttaccaaagc ctgaacctcc gccaaaatcg gacgcgtccc ttccatggtt acaacgatgg
     7921 aggaaccagt cgccccatcc aaacgctctt ctaggaaaac ttgactcgga ttgagtacct
     7981 caaccaagcc gcccgactgc atctcaaaaa tcccaatctc attagtggaa ccaaaacgat
     8041 ttttgaccgc tctcaaaata cgaaaggtgt ggtgacgctc cccttcaaag taaagcaccg
     8101 tatccaccat atgctccaac atacgaggcc cagccaaggt tccttctttg gtcacatgac
     8161 ctacgataaa gatggcaatg ttattggtct tggccaactg catgagttca gcggtcactt
     8221 cacgcacctg agaaacagac ccctgcaccc ctgaaatctc aggagacatg atggtctgga
     8281 tggaatcaat aatgagaaag tctggctgga tacgctccac ttctgcacga acactctgca
     8341 tattggtctc tgcatagaga taaaactcac tatcaatatc acctaagcgc tctgcacgta
     8401 gtttaatctg ctgggcagac tcctccccac tgacatagag aactgtcccc acttgggaca
     8461 actgggttga gacttgtagg agaagagttg atttcccaat cccaggatcc ccaccgatga
     8521 ggacgagact tcctggtaca actccgcctc caagcacacg gttgaattcc tccatctccg
     8581 tcttggttcg attgacattg atggaagtca cctcagctag tttcatgggc ttggttttct
     8641 cacctgtcaa ggacacacgc gcattcttga cctcggcaac ctcaacctct tccacaaaag
     8701 aagaccaaga cccacagttg gggcaacgtc ccagatattt aggggaatta tacccacaat
     8761 tttgacatac aaatgtcgct tttttctttg cgatgacaaa cctctttcta tatctctaac
     8821 tcacactcaa tcacttggca aaaatcaatc ttctcatttg gcacaaactg gcgcatgagc
     8881 attcgatgag caacaactac cacagtctga tgttctcgat acttagacat acattctaga
     8941 aaccgagact tcatttccgt agctgtctca tattgaatag gactattagg aagcaactcc
     9001 cccttgtttt ctaaaaacag tcttctagct gtttcaaagt tttctattcc tgttttatag
     9061 acctgccatt catgtaataa aggctctact cttaaaggaa gacccgtagc acagaccaca
     9121 tacgaagccg tttctaaagc tcttgtgact gcagaagata cgattatttc agctgacgag
     9181 agtaaaggag ttttgctcaa tttctggact tgctgccgtc ccatctcaga caagggtgcc
     9241 aaatctatcc caaatcctat ataaaaacgc tcctctaact cacggtaatc tggctcccca
     9301 tgacgtacaa agataatctt cattctagtg ccctgtcgat ccaaatccac cagttcgaac
     9361 gccatcagcc gcatctccat ctgcaattaa gaaagtagca aaaacagcct ggacaatacg
     9421 ctccccaact tcaagaacaa cctcttggtc tgtgatattc ttcatctgcg caaaaatatg
     9481 cccttcattt ccaggatttc cataataatc cccatcaatg accccaactg agttaattaa
     9541 aaccaagccc ttcttacgag gatttgaaga acgatcatag aggtagagaa cctcagtcgg
     9601 ctgcatataa gccttaaccc ctgtcggaac caagacaatc tctcctggcg caacaactgt
     9661 acgcacagca acctttaagt cgtaaccagc cgcatgcgct gtctcacgct tgggcaataa
     9721 attttcatct gtaaaactcg aaaccaattc aaaaccacga attttcataa ttttctcttt
     9781 tctattatca tttattctag attattctat cttatttatt cggaaaaagc acgaaaaaag
     9841 agcacacaat tcaaatcgct tagggctgct ggattcctcc cctgacccgc ttcacgcaga
     9901 actgttgctc cactatttat tatatcacat tcctattcat tttaaaagca aaattatttt
     9961 ttccgtctat ttctaaaaaa atcctgcatg atagctgcgc attcatcttc caaaattcct
    10021 atttcaacct ccacacgatg attgagacgc tcatctgtca agatatcgta caaactccca
    10081 gcagcgccaa atttctggtt tttagcccca tagaccacat ttggaatgcg ggcaagccca
    10141 atcgccccac tacacatgac acaaggttca atggtcacaa aaagtgtgca atccagcaag
    10201 cgccagctct cctcactcaa gttcgcatcc tctatagcca taatttccgc atgcataacc
    10261 gctcgctgta attcctcacg cgcattatgc ccacgaccaa tgatttcccc atctttgaca
    10321 atcacacaac caattggaat ttcatcgtgt tcaagagcaa tctcagcctc tctcaaagcc
    10381 tccctcataa agacttcttt ttcttcaagc gtataataca tctcttttct cttttcctac
    10441 ttatcgattt tattattata tcatgaatcc caacacaaaa aaagccaccg aatgcggtga
    10501 ctctataggg agattattat gaaaaagaaa agtttaggat atttgttaca acaagttagg
    10561 aggtcttctt gtaaccgtct atagtatacc cgacctatct taaacaaatc ttaaaaatct
    10621 cttaggacca aacactttct aaaatatttg tttgttcacg accaggacct actgagaaag
    10681 tagaaatacg aacgccaacc aattcactca cacgacgaac atagttacgc gcattctcag
    10741 gaagatcttc caaattgcga actccggtaa tatcttctga ccaacctggc aactcttcat
    10801 agataggctt gcaacgtttc aattgctcaa gactagctgg atagtagtca atacgttgac
    10861 cgtcaagatc ataggccaca cagattttca cagtatccaa accgctcaaa acatcaatag
    10921 agttcaaaga aaggttagta ataccagaaa cacgacggct atgacgcatc acaactgagt
    10981 caaaccaacc tacacgacgt ggacgaccag ttgttgtacc atactcatga cccacttcac
    11041 ggatacgttc tcccacttca tcaaacaact cagttgggaa aggaccatct cctacacgac
    11101 tcgtataagc tttacataca cctacaacct tgtcaatctt gcttggaccg acaccagaac
    11161 caattgtcac accaccagct acagggtttg atgacgtaac aaatggataa gtaccttggt
    11221 caatatctag cataacacct tgtgcacctt caaaaagcac acgtttgcca ttatcaagcg
    11281 catcattcaa gataacagat gtatctatca cgtatttctt gatttgttga ccatattcgt
    11341 aatattcttc aaaaatatca tcgaaaacaa tcgctttact gtcatacaat ttttcaaaaa
    11401 gacgattctt ttcagcaagg ttacgttcta aacgctcacg gaaaatatct ttatctaaaa
    11461 gatctgcaat acgaattcca acacgagcag ccttgtccat ataagctgga ccaattccct
    11521 taattgtcgt accaatctta ttgtcgccct tagcttcttc ttgcaagcga tccaactcga
    11581 tatgataagg caaaataaca tgcgcacgat cagaaatacg caagttatca gttgttacac
    11641 cttcctcatg aagatagctc aactctttta caagagattt aggatttaca accataccat
    11701 tcccaatgac agatattttt tcagggaaga aaatcccaga tggaatcaag tgcaacttaa
    11761 atttcttacc gtcaatcaca atcgtgtgac cagcattatc accaccttgg taacgtgcaa
    11821 tcacttctgc attcgctgaa aggaagtctg taatcttccc tttaccttca tcaccccatt
    11881 gggtacctac aacaacaact gaagtcataa tcttgtctga gccctcaggc tcttcctttc
    11941 tcacatacat ggcaggactc tcacctgcaa ttatatctta caatttatta taataaaaaa
    12001 tcgccttttt atcaagaaga aacaatagaa agatttgcta tttccaacta ttaaaaaatg
    12061 atttagaaaa attactagct atttactatt atctttccat aaaagagtaa attagttcgg
    12121 aaatttacta aaattacctc aacaagaaat aaaaccccga ttcattacca atttttcaag
    12181 atacaaacga taagcaacac gataatggta aacgataaaa tccctacgac aaccaatgcc
    12241 atatctcact aaataataaa ttaaaaattt aaaatgaaca tgttcccagt caaaattatc
    12301 accaaatgta ggaccatact cttcttcaat actatcatag aaattagtca tctgctcata
    12361 aattttttgt aacataatca aatactcctt ttctttttta taaacttatt ctaacaaaaa
    12421 attttacaca ttcactatca attcctgaat tgttaaaata ccagcctcaa caagataaaa
    12481 ataggaaaag ttgacaaaat agaaacaaat ttgctaccta aatttcaaac gattaaagtt
    12541 ctaaaaagac cgccttaaaa cttttgggta aatcctatta gaactataat atttatatat
    12601 atgtattatg gttctgattt tctagtataa aaaaattcaa actagaattc ttcttaggaa
    12661 aggccgtttt aagtgctatc attgctcaaa aatggaggtc gctgagactt ctatgaccga
    12721 cattgatcat cagttgtcta tttcaacttc aactgtcatt cgcaagatca ataattttca
    12781 ctttgagcat gatttttcgc gtcttcctga gattatgtcc taggacgttg aaacagtccg
    12841 gggagtgact gttttaatcg ggagatggag atgagcttta ttgctcagga ctttaataag
    12901 ctcaatatca taactgttct tgagagcaga atacaagcca tcatccgaaa tcccatgaat
    12961 acaaggctat caagcgttac tggaagctca ttcaacaaga tagtcagaaa ctgagtgata
    13021 aacgatttta tcgccctact tttcgtatgc acttaactaa taaagaaatt ctagataaac
    13081 ttttgagcta ttccgaagac ttgaaacacc actataatct ctatcagctc ttgcttttcc
    13141 acctcttttt cagactctgt ttaaaacctt cctcaaagat aaagagaaaa tcgtcaacgc
    13201 ccttcaatta ccttattcca acgccaaact ggaagccacc aataatctca tcaaacttat
    13261 caagcacaat gcctttggtt ttaggaactt tgaaaacttc aaaaaagaaa ggacgaaatt
    13321 tgtcctttct agatcttcgc tttcttcaac ccactacagt tgacaaagaa ccgaaaaatg
    13381 tctcgcctct aatatagtca attgaaacaa gaacaagaca aaagagcctc ataaaaggta
    13441 ttgcaacttg gtaatacctt tttgaggtgc tttttgatat gagcccatgt tttctcaata
    13501 ggattgtact caggcgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcttcacac
    13561 aagagtgcta gcttacccat tctatggaat cttgcattgt ccataatata gtagattgaa
    13621 actagaatag tacacctcta cttctaaaac attgttagaa ttcgatttta ctgttctaat
    13681 cgatttgtcc tattcttatt tcattttact ataacacgaa atagattatt attacataac
    13741 aaaaaagagg tctaaacctc ttaactaaat tactccgcca gtaggactcg aacctacgac
    13801 atcatgatta acagtcatgc gctactacca actgagctat ggcgga
//
LOCUS       DAVDFK010000045        13468 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.45, whole genome shotgun sequence.
ACCESSION   DAVDFK010000045 DAVDFK010000000
VERSION     DAVDFK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.45"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(10..870)
                     /locus_tag="VUR04_001738"
     CDS             complement(10..870)
                     /locus_tag="VUR04_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET5341602.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(1049..3103)
                     /locus_tag="VUR04_001739"
     CDS             complement(1049..3103)
                     /locus_tag="VUR04_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET5341603.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(3115..3369)
                     /locus_tag="VUR04_001740"
     CDS             complement(3115..3369)
                     /locus_tag="VUR04_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341604.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(3362..3919)
                     /locus_tag="VUR04_001741"
     CDS             complement(3362..3919)
                     /locus_tag="VUR04_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5341605.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDIVVDATMGNGHDTLFLAKLAKKVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(3903..4859)
                     /locus_tag="VUR04_001742"
                     /pseudo
     CDS             complement(3903..4859)
                     /locus_tag="VUR04_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            4951..5310
                     /locus_tag="VUR04_001743"
     CDS             4951..5310
                     /locus_tag="VUR04_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET5341606.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LIFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            5520..6376
                     /locus_tag="VUR04_001744"
                     /pseudo
     CDS             5520..6376
                     /locus_tag="VUR04_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6623..13324)
                     /locus_tag="VUR04_001745"
     CDS             complement(6623..13324)
                     /locus_tag="VUR04_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET5341607.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHTVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPRTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGDDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVATVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
BASE COUNT         3809 a         2968 c         2572 g         4119 t
ORIGIN      
        1 gataaatagt tagtcttttt taaagaccgg atctttcaaa ctctgcatac tggcattgat
       61 aaccgcgcct aggataacaa ttttagcaat caagataaac caaaacatca taacaacaag
      121 aagaacggaa cctaaaattc ggacatccac caaatgatgg acatagtaat tgagataact
      181 agagaacaga gttagtaaac ctaaaatcac taagagaaca aaggcactgc ctggtagggt
      241 atagctaatt ttcctgttag atagattggg aagaaaataa taaagcatga ccaagatagc
      301 aaagaggagg gcgtaaatca gaggacctgc caacccttgt aaagcctgat agataatgcc
      361 atcttttgtc caataatgag caagtaaagc caaaatcatc tgaccaaata agatcaaaaa
      421 caaggcaaac gcaaagagga gctgcaagcc aaaactgact aggagactta gcatctgatg
      481 agaaataagt ccacgactct tttcgacgcc ataagccttg ttaaaagctt tttgcaagaa
      541 attcatagat tttgaaaaac tccataacgc cgataaaaca gaaaaactca ataaacctgt
      601 tgaaggttgc gtcaagactt ctctggctat tttttccaca ccttcataga ggcttggggg
      661 caggacgtct ttcataaagc ccagaaattc tcccacagga atctgaaaat aggggaggat
      721 attgaccacc accaaaagca gggggaaaat cgaaatcaac caatagtagg ctactgcgac
      781 actggtcaac tcactatctg atgcttgata ataatgcaaa aaagctttta ataaaggctt
      841 gtctatcagc tctttccacc actttttcat gtcacactcc ttcacttata atcttatact
      901 caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa cactgttttg
      961 aggttgtaga taagactgac gaagtcagtc acatacatac ggtaaggcga cgctgacgtg
     1021 gtttgaagag attttcgaag agtattaact aatttcttct taccaattcc accatatcat
     1081 acggcagggt attggcagct tccttcaagg aatagttctc taagttattt acattttgtc
     1141 gtaatttctt ggcatactta gttgtaatta atcgtttttc ttcgtattcg aaaatcaact
     1201 tgcgctccag ataatagcct ctcagcattt cattgatatt gttgggtttg acacgattga
     1261 taacccgttc gacaaaggca ccactgctga taatagttgt ttctcgaaga cgagactcct
     1321 gcataaaact aatcaaagag cgtctgtaga ctcccttcag gttttccaaa ctttcaataa
     1381 tcatctccgt attggcaaga tagagctctg caatttggtc ataatcaaga gcacggagac
     1441 ggctttgctc cttgttcttc cagctacgga aggtctttcc gagagtaaaa acttcatgaa
     1501 ggagaaaacg taaaatcctc aaggaaacaa gaaaataata ggtcagtctt gaggcaagtt
     1561 tacgattgat tccttgttct atatttttca gataacgttg gtaaactcgg taagcacgat
     1621 tgctaatgtt cccctcttca taggcctgtt ccaaaccatc actttcaata ctaagaatca
     1681 agagtttcaa agcagcccag tcttcttgat catcctggtt ttcttggctt aaaatgagat
     1741 tttcaatacg tccatgataa ttgtcaatag ccgcatagag gggaagttta tttctggtgt
     1801 cttccaactc tttttccaac tctagcgtta cttcattcaa aatggcgata tgcatgagat
     1861 aatccttgct ttcttcctct tcatcagaaa gatgaggcaa gaccaagaga cctgttaaaa
     1921 agctgacaag cgtcacacct gcaacaagga aaagcaagag aggatactcc tgttctagat
     1981 tacttggtat caagagaatc gtagcaatcg acaccgttcc cttaacacct gaaaaggtca
     2041 agagaaacat gtccttcata tacttattta gctttttctt gaggcgtcgg gttctatagg
     2101 cataatagcc atagatcata ataaaacgaa tgacaaagag gacaaaggta agggcgatga
     2161 gagatagcaa taaaagtaga ggattataga ttggattggt caagataggt tctgctatca
     2221 tttccaactc catccctaaa atcacaaaga cagaaccgtt gagcataaag gtcactgtat
     2281 gccagaccgt ctcggtcacc gtatccactt gggcttcgag gagcgtgatt ttcttgaagc
     2341 gacttgcctt taaaattcca gcaactacga cggcaataat ccctgaaaca tggacttctt
     2401 ctgccagaaa gaaggtcact agaggcaaac tcaattctaa taaaagttca ctggcaatat
     2461 ccgttgcgcg cacacttagc aagaaggtat ggaggaagcg gttggtcatg gctgttaaaa
     2521 atccaattaa aaaaccgcct aggattgaaa agatgagcga actgctagct tgccccagag
     2581 aaaaagctcc agttgtccaa gctgtcaaag ctacctgaaa agccaccaaa ccagaagcat
     2641 cattcaagag tccttcgccc ttaagaatat tggacacgcg cttaggaaag ctaaaacgct
     2701 ccgaaagaga ggcaaaggcc accaagtccg taggaccaag ggctgcccca acagccaagc
     2761 aagctgccaa gggaaggctg aaccaaagaa gatgggccaa gccacccaaa ctcagggtcg
     2821 agataaaaat cactggaaat atgagataaa caatgattcg ccagtgtttt aaaatagccg
     2881 taacatctgc ttcttcagcc tctcggaaaa gcaagggtcc gataaccagt gccaaaaaca
     2941 actccgtatt aaggtgaaag tcagtattgg gtaaaaagag accaatcaca attcccaaaa
     3001 gaatttgcac caaagggaga ggcaaaaagg gcaggagctt attggttgta cttgagacaa
     3061 tcaaaaccag taaaaacagg atgaggtaaa tcagtaattc cacgcacgtc ctccttaatc
     3121 ttttttacaa caggattcaa atatctcctt ctgctctttg attttttggt caatcttgga
     3181 acagtctttg tgctcaattt ttctctggca ccgttccatt tcaagagcaa ctaatttttt
     3241 cttgatttta agcatttttt tgctcatatg cgcttggtct agcacgccca ccgatcgttc
     3301 gtggtgggtt gattcaacaa aattctggcg catggcatcc agcttttcgt gtaggtattg
     3361 tttatccatg tctgtatctc tctaattttt caatcatcac taaaaacggc gggttgttga
     3421 cttggtttaa agttcggtaa atggcagctg tgtactcttg ttggttcaac tggattacaa
     3481 aatccaagac agcatctctc tcgaggtcgc ctccttcatg accatagtaa atcataatag
     3541 caattcgtcc acctttgaca agtaagccac atagcttttc taatgcctca atcgttgtct
     3601 gcggtcgggt gatgacagac ttatcagctg acggcaaata gcccaaatta aaaatccctg
     3661 ccttagcttt tgtcacaaac tggtccagtg tctcatggcc ttgcaagatt aactgggcat
     3721 ttgtcaagcc agcctgatgc aaacgctctt gggtcttttc caaggcttgc ttctgaatat
     3781 caaaggcata gactttcttg gctagtttgg ctaaaaaaag cgtgtcatgg ccatttccca
     3841 tagtcgcatc cactacgata tcctcttttg tcactacctc agccaaaaaa tcatgtgcca
     3901 tctcaagtgg tcttttcatt ttcaaactcc tgttttacaa ccttgcatcc ttgaacactt
     3961 ccacgacgtc gcatttcagt ttcaatagca tttagcactt cccatttatt gaggctccac
     4021 atagggccaa ttagcatatc tcgaggtgca tctccggtaa ttcggtggat gacgatatgc
     4081 ttgggaatga tttccagttg gtcacagatg accttgacat attcgtcctg actcatcaat
     4141 tgtaaacgtc cctcatggta atctcgttgc atacgagtat ttgtcataag atggagcaaa
     4201 tgcagtttaa tcccttgaat atcgttattc gtgacacaac ggcggacatt ttcaaccatc
     4261 atctcatggg tttcaccagg caaaccatta atcaaatggg aaacaatctc aatcttggga
     4321 tactttctca aacgcttgac cgtttccacc tacaattcat aagaatacgc acggttaatc
     4381 aggtcagagg ttgcttcata agtagtctgc aagcccaatt caaccgtcac atgcatgcac
     4441 tccgataact cagccaaata ttcgatggtt tcgtctggta aacagtctgg gcgcgttcca
     4501 atattgattc ctaccacacc tggctcattg atagcctgtt cataacgctc tcgaataact
     4561 tccacctttt catgggtgtt ggtaaaattt tgaaaataaa ccagatactt ctgaacatct
     4621 ggccacttac gatgaataaa gtcaatttcc ttataaaatt gctcacggat aggcgcatct
     4681 ggtgccacaa tggcatctcc agaaacggaa accgtacaaa aagtacagcc tccatgagcc
     4741 acagttccat cacgattggg acagtcaaat cccgcatcaa tagggacttt aaaagtcttt
     4801 tctccaaaga gttttcgata ataatcattc aaggtattat aagattttat aactttcatt
     4861 ataacaaaaa tcacccacaa tctcaaaagc ctgactttcc tataaattcc tctgtttctc
     4921 gtttccatta gccttttttt atgatacaat atgggtatga ttttaatgaa attagcatct
     4981 attttattat tgatactgac cttagtcgtc tgcattatcc taaccaaact ttttagatta
     5041 aaaaaactag gacgaaactt tgcggatttg gcttttccag tcttgatatt tgagtattac
     5101 ttgattacag ctaaaacctt tacccataat ttcctcccta gactggggct agccctctcg
     5161 ttcctagcca ttattctcgt ctttttcttc cttttgaaaa aacgcagctt ttactatcct
     5221 aaattcatca aattcttctg gcgtgcagga ttcttattaa cccttatcat gtatatagaa
     5281 atgattgttg aattgttctt aatgaaatag tcgaatccct aagcattttc tagggatttt
     5341 tgctttctct acaaaatagt atagacaata acactataca attttataca aagaaaagag
     5401 tctgggacaa tagtctctta tatccaaaaa ggcaacggat ttgccgttgc ttttttgcat
     5461 ggttacgata gtcttggtaa aatagaattg cttaataaac catttagaaa ggctatccca
     5521 tgcatattca ctataacaca aatcaaacaa ctttaccact agaaatcagt tccttcttac
     5581 cacaagacca tctcgtcttt actattgaaa aagtggtgac taccttggag gaacgtcact
     5641 tctacgcctt ctatcatgcc tttggtcgcc cgtcttatca ccctaaaatg cttgtatcta
     5701 ctcttctatt tgcctattca caagggattt tctctggtcg aaaaattgaa aaatggaaga
     5761 gttagtgacc ttagattgtt tgtttattga cggaactaag attgaagcca atgccaacaa
     5821 gtatagtttt gtgtggaaga aaacgacaga gaaattctcc gccaaacttc aagaacagat
     5881 acaagtctat tttcaagaag aaatcactcc ccttctgatt aaatatgcca tgtttgataa
     5941 gaaacaaaag agagggtata aacagtcagc taaaaactta gcgaattggc actataatga
     6001 caaggaggat agctacatac atcctgatgg ctggtgctat cgttttcacc atatcaagta
     6061 ccagaaaaca cagacagact ttcaacagga aatcaaggtt tactacgctg atgaacctga
     6121 atcagcccct caaaagggac tgtatatgaa cgaacgctat caaaacttga aagctaaaga
     6181 atgtcaggcg cttttatctc cccaagatag acagattttc gctcaacgca agattgatgt
     6241 ggaacctgtc tttgggcaga taaaggcttg tttgggttac aagagatgta atctgagagg
     6301 caagcgtcaa gtgagaattg acatgggatt ggtacttatg gccaataacc tcctaaaaca
     6361 tagtgaaatg aaataagaac aggacaaatc gataaggaca gtcaaatcga tttctaacaa
     6421 tgttttagaa gtagaagtgt actattctag tttcaatcta ctatacaata agagaacgac
     6481 tcaaaattaa aaagctagag ttccgcaatt ggaaatctct agctttttgt ggttgagaac
     6541 tattttgtcc cagactcttt atcttctatt taggacaaga gtttttcttt ggtctttaat
     6601 gataaagaag gtatcaaaat ttctagtctt cttttttacc tttagtaact actaatcctg
     6661 cactcaaacc tagaagagct aaacctgctg ctactgctgc ttgacttgcc gcactacctg
     6721 tatttggtaa ctgggcttta ttagtttgac tagcttcact tgaatcaatt ggttttgtat
     6781 ctgctttttc tgacacttgt ggttttttag cttcttgagc tactggtttg gttccaacca
     6841 agacgatgcg gtctgtcgga gcttctacca cttcacggag tttttcttcc ttacttccat
     6901 caggattaat cgctgtaaag atacgttctt ttccaacttt tccttcttgt tctacacgag
     6961 tttcacctag atacagtgtt gaatcttttt tctcaactgt cttgtaggcc aaatcttttt
     7021 caacaaattc gagttttgga agatcttctt gtacagtagc aacagtcttc tcagaaactg
     7081 gtttttcctt agtcaactgg atacggtatt ccttgacttg ttttccactt tctgaaacga
     7141 ggcgaacaag tactggaagg ctatcgtctc cgctatctac cacagttgaa gctacttgat
     7201 tgttttcttc aactgagact tttggccgtt gacctttata ggtaatttga tagtcttgac
     7261 gattttcagc gaaatcagca agttcttttc catctacaag aatcttcgat tgcgtacttt
     7321 cttgaggcaa ttcactcggt gcaaggaagg tcatctcaat catcgcaaca ccgctcttgt
     7381 cagctttacg ctccatacgc catctcatag ctttggcttt gacagcttta aatgttacgt
     7441 tgatttcatc accagctgcg atgtctttat ccgcacgata aggcacagct tcccaatttt
     7501 ctggattgtt gaatggatgg tctgcgtcgt aggcttggta gtttgaatag taggttggca
     7561 cttcaaactc tggaccgaca tagcgttcta aaacgagttt agttggtgca tccgtaccac
     7621 tatctgcaaa gaaacgaagt ttggcttggg caacagtccg ttctacaatc ttaccatttt
     7681 cacggaagat cacacccgct gatacttctg gattagaaga tggtgttgga gaccagtttg
     7741 tccaacgacg attttctgaa tgatctccgt cattgagata gtcaacgcgg tcatgagagt
     7801 ttttgtcaat atcattggtt gctgaagcaa aggcctggtt actgttttca tcatagttag
     7861 ggttatctga aagagcttcg cctagtttgt ctgtcactcg tacagtgacc tcagcaacaa
     7921 gatcactacc aaggacacgg cctcgaacag taaattgacc tgcttttgtc agattttccg
     7981 ctggaacttc ttcccattca actgtcaggt cttttgtttc gtagccgtct ttacctgtga
     8041 agtaaactgg aaccttagtc ggcaattcaa gtgcttgacc tacttgtagc aagcgagctt
     8101 gtttaaccgc agcaactggt ttatgagaaa gtaagttctt atccttagtg aagtgcagac
     8161 ggtattctcc taagatgtcg ccattttcag ctttcgcgat gacacgaact ggctcacctt
     8221 cacgaacgct tggaacgacg gtagcgagac cattgttgct aacacttgct gtgactgccg
     8281 gaacttttcc atctacagac tcaaggtagt agtctgtcaa atcagggttg aagtttgcta
     8341 agtctttgcc gtcaacttgg attcttgttt gtccttgttt ggctgccgca acttgtttcg
     8401 caaagatttg tacctctgtg atagacgttc cacgcttgtt atctgcttta accatgcgaa
     8461 tacgaatagc ataggtttca actttatcaa agctaaagtg gttcatttct ccagccttga
     8521 gttgagcagg ggcttttaga ttagtaactg gtttccagtt ggcagaatca ttaaagacat
     8581 ggtcctcatt accaacaaaa ctagggtttt taggagctgt tgggacagtc ttaccaacat
     8641 aatactcaat cacataagac ttcggtgcac caactccatg gtcttcgtgg aatccgacac
     8701 ttagattatc aacggagcgt ttgctcaaga tacctgaatc tccaaacaga acaccgactg
     8761 aagcttctgg attactacga ttccagtttg tccaacgatt ggctggttgg ttattgtagg
     8821 aaatgagctt gtcattaaca tttgaaactg ggtcgcttgg atttgaatct gaagcaaagg
     8881 caagtggcaa ttctgaaccg gtccattggt cagaaatgtt tgcaccttgc tcagtttgag
     8941 cagatacgcg aacatgaagt ttagttgtta attgcgtacc ttctaagcga ccattaactg
     9001 taaagacacc ttccttagcg tattgctctg gacgaatcgc atcccatgca accttagctg
     9061 atgaaacgtg accatttgaa tcatatgtcc gaacgctttc tggtaattgt ggtgcttctg
     9121 cgattggagt tgtcacactg acttcttcaa ctgaaacgat accttctaca gagacttttg
     9181 cacgcgcttc aaggtcaatt ccttcaactt tacctagtac ttcaaatgtt tgataggagt
     9241 ctagtttttc tttcggaata gcttgccaag tgactttatg agttctaggg aaacctttgt
     9301 catactcaac tgttactgtt gctggaagac ttggttcctg atgcaaatct gtcactacat
     9361 ttacaggacg gatggattgc gcaatcttct tctcagtatt ggcttggata gtgagttcaa
     9421 cttggccttt agctccctca tattcagcgt tcagagtgac tgctcctggc ttatgcaact
     9481 caagcattcc tttacgaatt gcgacttccc cttcaccact tgtagagaag gttactttat
     9541 cagctggtaa tacagcttgc gttccatctt gatagtgagc tcgaaccgac aatttgacag
     9601 tttggtcttc tttgagactg tcagcttttt ccacttgcaa gctcaagtga gcaatttttg
     9661 gtgcttcttc taggaattga attgcatagg tttgaagagg gccaccatct ttaggctgaa
     9721 caaatatgct tgcacgcatg ccgtttgctg cgcttgcttg aagaactgta acagctgcat
     9781 ttttagcact tgctgtgact tctggcaact tagctccata agcaagagtg cggtattgca
     9841 ttggtttttg actagtaaga cctgtgacag cttcaccacc aaccgttaca gttggtactg
     9901 caggtgccgc aggattgcct tcttctacca caagggttgc atgaattggt tgaccttcta
     9961 aataaccggt cgcttgaata cgagaacctg gaattgctaa cttagcttta tcttcttcgg
    10021 caatctccca cttgtccact tcatactctt gtacacttcc atcagtcaaa acataggaaa
    10081 cagatttgtc tacagaattc aagtcagtat ttggagcaat acgtttcaca actggtagct
    10141 ctgatttaag agcaatcact tctacacgag cttctacttc tcgtccgtca gccatacctt
    10201 tcaccgttac aataccaggc ttgctcacat ctactgaaga ccaggttaca ggacgttctg
    10261 cacggctacc atcactgtat acaaacggaa cagtggtagg catttcaggt gcctctccaa
    10321 taatggtctg tacttttggc acttctgtca ccaaaacagt cttctcttgt ccttctttct
    10381 taccagtaaa gacagtgact tggttcgatt tcaagagatc agagtgggca gtaagggtga
    10441 atttccctgc ttgttcagtt gatttgacaa tggcaacacc tttaccatta aatgctttac
    10501 gaatccaaga accatctgct tgcgccttat agcgttcacg gctggcttgt tctccgttat
    10561 ctacaccgac cagttgacct tgaccatgca attggaagcg aaccagatta ttagcagttg
    10621 gaaccacatt cccctggctg tcaacaattt catagtagat gtaagtcaag tcttttccat
    10681 ctgctgcaat cgcatggtct tccttaataa gacgaactgc cgctggctta ccagcagtcg
    10741 taatcttatc tcgagcaatt tccttgccag attcatcacg agcaattgct tccaaggtac
    10801 ctggttgata ggcaactttc cattcaagat aaagttcatt agcatttgca ccttcttggt
    10861 aagtccgccc atcgctggtt tgttttttat tgaaagtctt aagaccaaga gattttccat
    10921 tcaagaacaa ttctacacta gaagcattcg aataagcacg aactggaatc ttaccttctg
    10981 agtcagctac tttggatgct aattctttgt tttcccagtt ccagtgagga agaaggtgta
    11041 ccatcggttt cttcttaaca gaaacccatt ggctttggta gagatagaag tcatgttttg
    11101 gaatgccggc tgtatctacg ataccaaagt aagagctctt aacaggagtt tgattttggt
    11161 tgtgccatgg tgtaggttca ccaatatagt ccgtacctgt ccagataaac tgtccagcat
    11221 agccagcgtt gtcacggtca aaagtccatg aagcggttgc tgttttcccc caacccacac
    11281 gatcattccc atagtcagac tgttcataat tacgctcagg tccattgcta tgtttcaatt
    11341 cacgttcagg gcgatagtaa cttccacgtg tacgggtagc tgaagatgtt tctgatccat
    11401 aaatcaacca ttttggatgc ttagctctaa gggctttgta attatcttca gaatagttaa
    11461 atccaacagc atcgagttca tcagcaattt tctcatgccc tccgctacca ttaccgaaac
    11521 ggaatttatc tgctcccatg gtaacatagc gagtcttatc aacatccttg ataaccttga
    11581 ccaaacgttt aacagttact aaagagtggg catcaccatt agcttcacct atttcattac
    11641 caattgacca catgaagata gcagggttgt ttttgcctct ttcgaccatg gtacgtaggt
    11701 caaaatcaga ccatttttca ccttttcgag cttctgggtg agtggcatct ttttcaaaga
    11761 aacgtccata gtcataaggt ttcttgccac cataccacgt atcaaaggcc tcttcctgaa
    11821 cgagtaaacc tagttctgct gcgatttgca aggtttgctc actagcaggg ttgtgggttg
    11881 tacggatgga gttaactccc atctccttca tttgtttgag acggcgatat tctgctttat
    11941 agttttcttc tgctccaagc gccccatggt cgtggtgcaa ggatactcca tggaatttaa
    12001 tacgttcacc attcaaagag aaaccttcat ttggagtcca gtgatagtaa cggtaaccaa
    12061 acaaatcctt cttagcatca accaattgac cgtcacggta aacacgcgta atcaattcgt
    12121 acaaggcagg tttgtcattt aaaacggtcc agagttttgg tctttcaact tctaaaatcg
    12181 catctaggct tgttgattca tgtgctttta aggtacgact cgctgtacga actaagcctg
    12241 ttacagtatg accacctcgt tcaacgattt gatattcggc tacaagttca tggtctttgt
    12301 cgtccgtatt gacgattttg ctggtcacat gagtttcaac cttgccatgt tgttgttctt
    12361 caagttttgg tgttaaaata gttgtcccat ttttctcaac atgcacctta tctgtcactt
    12421 gtaaagtcac atcacgatag ataccacttc ctgaatacca acggctactt ggctgtttgt
    12481 tgactgcatg gacagcaatc acattctcac gaccatcttt gtgaaggtat ttggtgatat
    12541 cgtatgagaa ctggttataa ccatttggat aatgccccac taactgacca ttgacataaa
    12601 cttgagaatc catatagacg ccatcaaaag taaggcgaac atttttcttg aggtcttttt
    12661 catctagttt gaaagtcttg cgataccaag cttccccacc gttgagctgt ccaccttcat
    12721 tttgtgcagg agattcatga tcgaaatcgt taaagatact ccagtcatac ggtaaatcta
    12781 attttttcca cgtagatacg tctgcatcag gtttaatggc ttccttagaa tttgcattga
    12841 gtttaaagta ccaattttga ttaaaatcca ctttcctgtc ttcaatcatt tgattcactt
    12901 cttcatttgt tacagcttta gcatcttcct tgagcggttt ttcttgactt gaagcttgtg
    12961 attctatcct tggagctttt tcttccggtt tagcagacac tttttcctct tttggagtta
    13021 cggcttcatc ttctttcttc tcagatgcaa tagcctcagt tgaactaggt tcactttgtt
    13081 ctgtcctttc aactacattt ttagtttcca aagctttatc agccttttct tctactatca
    13141 ttttttcctc tttaggtttc tcagcagtat gagtaataag tgtttcatcc gcataaacta
    13201 cagattctcc agctatattt cctcctaata gaactgcaca agtcccaatc attactgagc
    13261 aagctcccac agcaaactta cgaatgctat aaactctttt ccgattccaa tggcctttcc
    13321 ccataaaacc ctccttatat tatatttagt gcagttagct actactaaag cccaagtggt
    13381 atacatggta tgacaaccta gtttcaacaa tttacactct gcgaaaatcc aattcaaact
    13441 tcgtcagtgt cgccttgccg tatgtatg
//
LOCUS       DAVDFK010000046        11659 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.46, whole genome shotgun sequence.
ACCESSION   DAVDFK010000046 DAVDFK010000000
VERSION     DAVDFK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.46"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            6..473
                     /locus_tag="VUR04_001746"
     CDS             6..473
                     /locus_tag="VUR04_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HET5341608.1"
                     /translation="MKSGTSLEYSPLASVGAYKLLPNIVGNMETTPVERVEEEMRTLL
                     IGYNLNNAKELEYLITFHANFEKIHPFADGNGRVGRLLLYKECLKEGIIPFIVDDSNK
                     SHYYSALEELQLRDNKEPLLTYFQGEQKNYINDLKNKNFDGKINHAKEYSQKV"
     gene            1532..2215
                     /gene="tsaB"
                     /locus_tag="VUR04_001747"
     CDS             1532..2215
                     /gene="tsaB"
                     /locus_tag="VUR04_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET5341609.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETMINIKKNHSINLMPAID
                     FLMASLDLTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPR
                     QKEGLVVPIMDARRNNVYAGFYENAKPVLPEAHLSFAEVLEQVKDAEQVTFVGEVGAF
                     VEQIQEQLPQASYQETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            2212..2649
                     /gene="rimI"
                     /locus_tag="VUR04_001748"
     CDS             2212..2649
                     /gene="rimI"
                     /locus_tag="VUR04_001748"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET5341610.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            2639..3649
                     /gene="tsaD"
                     /locus_tag="VUR04_001749"
     CDS             2639..3649
                     /gene="tsaD"
                     /locus_tag="VUR04_001749"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET5341611.1"
                     /translation="MKDRYVLAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3689..4995)
                     /locus_tag="VUR04_001750"
                     /pseudo
     CDS             complement(3689..4995)
                     /locus_tag="VUR04_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5271..5622)
                     /locus_tag="VUR04_001751"
                     /pseudo
     CDS             complement(5271..5622)
                     /locus_tag="VUR04_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5729..6022)
                     /locus_tag="VUR04_001752"
                     /pseudo
     CDS             complement(5729..6022)
                     /locus_tag="VUR04_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            6265..7470
                     /locus_tag="VUR04_001753"
     CDS             6265..7470
                     /locus_tag="VUR04_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5341612.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYISSDTEGIPMCVLESMSQGTSVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            7463..8259
                     /locus_tag="VUR04_001754"
                     /pseudo
     CDS             7463..8259
                     /locus_tag="VUR04_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            8346..9961
                     /locus_tag="VUR04_001755"
                     /pseudo
     CDS             8346..9961
                     /locus_tag="VUR04_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            9981..10826
                     /locus_tag="VUR04_001756"
                     /pseudo
     CDS             9981..10826
                     /locus_tag="VUR04_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10855..11181
                     /locus_tag="VUR04_001757"
     CDS             10855..11181
                     /locus_tag="VUR04_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341613.1"
                     /translation="MENTLLNITGSFDMETRNLISYSLTDIFETDKIRIELLGEIYYK
                     NIKLELHEFAGLYKIYGISLIKNITGMFLIIIFDTKTKELKIFQDITTSYFNLYYTVY
                     GGVFYI"
     gene            11201..>11659
                     /locus_tag="VUR04_001758"
     CDS             11201..>11659
                     /locus_tag="VUR04_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="HET5341614.1"
                     /translation="MKLSHVPVTLNNKKIQEFMRNGFILDSNTLVTEINKLEYFSYIS
                     VNNTIRICGIDYNDSNNFTKEQVLKNWDSMLRESILRVYSEAGEANITLSSGFDSNYI
                     LYTLANYTNSSINAFCIGGEKGINEIPEVTKIAKFYGINLLVDTVMSQDLE"
BASE COUNT         3830 a         1787 c         2367 g         3675 t
ORIGIN      
        1 aaatattgaa aagtggaacc agtttggagt atagccctct tgcttctgtc ggagcctaca
       61 aattactccc aaatatcgta ggaaatatgg agacaactcc tgtagaacgt gttgaagaag
      121 agatgcggac cttactaatt ggatataact taaataacgc caaagaattg gagtatctta
      181 ttacttttca tgctaacttt gaaaaaatcc atccattcgc tgatgggaat ggtcgagtgg
      241 ggcgcttgct attgtataaa gaatgcctaa aagaaggaat cattccattc atcgtagatg
      301 attcaaacaa gagtcattac tactctgcct tggaagaact tcaacttagg gataacaaag
      361 aacctctgtt gacttatttt cagggtgaac aaaagaatta catcaacgat ttaaaaaata
      421 aaaattttga cggaaagatt aatcatgcca aagagtattc tcaaaaagtc taagagtaat
      481 atgtgagaat tcaaggataa tattgaaaag actctgtttt aggtcgaaaa agaaaaagct
      541 cttgacaaaa gtcaagagcc atctaacact gggggcgaac taatcaatcg caattccggt
      601 tatttagaag gcgaaccctc aaggacagca ccacagcctg aagagccaaa ggctcaacct
      661 gattttccta ccaatgttcg attatatttt aacattgaca agtcagtaaa gtcaagttat
      721 cggttgcgtg gtggctacaa ataccctgaa gatgcggaca taaggacttt aaataagtat
      781 gcggatgctt tgcaacggtc agcacaacaa tatttagata gatttgccaa tcaaaaaatc
      841 atctacgctt ttaacgaaga taaccaactg aacgctctgt taccagtcgc cctacgttat
      901 cctctagata tttatacttt actataactt acttagggaa tcaactttaa aagcatcaaa
      961 aagctcctga ccgaagtcaa gagccgtcaa acactggggg gcgaattgtt caatcgcaat
     1021 ttcagttctt tagaaaccaa agtttcaggg atagcactgc aacccgaaga gccaacgact
     1081 caacctgatt ttcctaccag tgttgaatta cattttaaca ttgatggtta aaagagtcaa
     1141 aggatttgcc atctttacgc ccttcttttt tctcagcaaa aatcgagttg aagcataaaa
     1201 agaaaacaat gcaaacagat gaatcaactg gtaagggtgt aacgattatg tttaaatcat
     1261 tgaaaatgat aagcaaacta taagagatga agagaataac attcatcctt ctaaaaatgt
     1321 gccttttatc tagcatgact tatctacact tcttacgaag aacctttcaa ttttcttgtt
     1381 cactttttta ttcgaaaaag atagaacttt tttgattttt tgccttcctc tttgtctaag
     1441 tggtgaggct ttttgtttgg ggagaaagaa aattcccatg cgctggcttt tgtagtataa
     1501 tagtaaacag acaaaaagat aggaatgtgt tatgaaagta ttagcttttg atacgtctag
     1561 taaggctctt tctctagcca ttttagagga caagcaggtt cttgccgaga ctatgattaa
     1621 tatcaagaaa aaccacagta tcaacctcat gcctgccatc gattttttga tggcgagtct
     1681 ggacctgaca cccaaggatt tggatcgcat cgtggtggca gagggaccgg gtagctatac
     1741 aggtttgcga attgcggtag caactgccaa gaccttggct cataccctga acattgagtt
     1801 agttgggatg tctagtctat tggctctggt gccacgccaa aaagaaggct tggtggttcc
     1861 tatcatggat gcgcgtcgca acaatgtcta tgcaggcttt tatgaaaatg ccaagccagt
     1921 cttgccagaa gcgcatctgt cttttgcgga agtgctagag caggtcaagg atgctgagca
     1981 ggtgaccttt gtcggagaag ttggagcctt tgtggaacag atccaagaac aactaccaca
     2041 agccagctac caagaaacct tgccaaatgc agctaatcta gctctttggg cctgggacaa
     2101 agaagcagac tccttgcacg actttgtgcc aaattacctc aagcgtgtcg aggctgagga
     2161 aaactggctc aagaaccata ccgagtctgg cgagtcttac attaaacgcc tatgatagaa
     2221 atcaaacgaa tccaacagca gcctgatcta gctaaagcca tctacgctgt tatgatagct
     2281 gtttacccag tcagtccttg gacgctggaa caaatccaag ctgacctgtt ccaagaccag
     2341 acttggtatg ctctggctta tgatggggca gaagtgattg gctttctagc tgttcaggag
     2401 actctctttg aagcagaagt cctgcaaatc gctgtcaaag gagcctatca gggtaagggc
     2461 attgcgtcag ccttgtttgc tcaattgccg acagataagg agattttcct cgaagtcaga
     2521 aagtcaaatc aacgagcgca agcattttac aagaaagaaa aaatggcggt catcgctgat
     2581 cgaaaggcct actaccatga cccagtcgag gacgccatta tcatgaagag agaaatagat
     2641 gaaggataga tatgttttag catttgagac atcctgtgat gagaccagtg tcgccgtctt
     2701 gaaaaacgac gatgagctct tgtccaatgt cattgctagt caaattgaga gtcacaaacg
     2761 ttttggtggc gtagtgcccg aagtagccag tcgtcaccat gtcgaggtca ttacagcctg
     2821 tatcgaggag gcattggcag aagcagggat taccgaagag gacgtgacag ctgttgcggt
     2881 tacctacgga ccaggcttgg tcggagcctt gctagttggt ttgtcagctg ccaaggcctt
     2941 tgcttgggct cacggacttc cactgattcc tgttaatcac atggctgggc acctcatggc
     3001 agctcagagt gtggagcctt tggagtttcc cttgctagcc cttttagtca gtggtgggca
     3061 cacagagttg gtctatgttt ctgaggctgg cgattacaag attgttgggg agacacgaga
     3121 cgatgcagtt ggggaggctt atgacaaggt cggtcgtgtc atgggcttga cctatcctgc
     3181 aggtcgtgag attgacgagc tggctcatca ggggcaggat atttatgatt tcccccgtgc
     3241 catgattaag gaagataatc tggagttctc cttctcaggt ttgaaatctg cctttatcaa
     3301 tcttcatcac aatgccgagc aaaagggaga aagcctgtct acagaagatt tgtgtgcttc
     3361 cttccaagca gcagttatgg acattctcat ggcaaaaacc aagaaggctt tggagaaata
     3421 tcctgttaaa accctagttg tggcaggtgg tgtggcagcc aataaaggtc tcagagaacg
     3481 cctagcagcc gaaatcacag atgtcaaggt tatcatcccc cctctgcgac tctgcggaga
     3541 caatgcaggt atgattgcct atgccagcgt cagcgagtgg aacaaagaaa acttcgcagg
     3601 ctgggacctc aatgccaaac caagtcttgc ctttgatacc atggaataaa gagtggctct
     3661 ttgtcaagtg tagtgggtag gcgaaaagct acaatctgga gagtacgaaa ttcgtactct
     3721 cttttttgat gttcaaagtc atcaaaatcc gttttttaaa attgttaaag ttccggaaac
     3781 caaaggcttt gcgcttgata accttaataa aattattggt cgcttcaagt ttagcgttgg
     3841 aataaggcag cttaagtgcg ttgataatct tatctctatc ccttaaaaaa gtccaaaaga
     3901 ccgtttgaaa aagcggatga accgttggca gttcttgctc aatcaatcca aagaaatggt
     3961 cggcattctt ctcttgaaaa tgaaagagca ggagttgata gagttcgtag tgaacctgta
     4021 atccctcaga gtaagaaagc agcttatctc gtacttcccg atgggttaag tgcattcgaa
     4081 acgtgggctg atagaatcgt ttctgacaga gcttgaagct atcctggtgt agtaaatcag
     4141 tccagtggac tgatttagcc cgagcctaga aacgaaaaag cgagggttcc aaaagcgctt
     4201 gagcgcccga tactccaagg attttcggtc aaattggttc atgatttgga ttcgtactcg
     4261 gttcatagct cggctcagat gttggacaat gtggaggcgg tcaagaacaa tcttcgcctt
     4321 tggaaagagt tgcttagcga gccgataata agggctgtac atgtccatgg tgatgacctc
     4381 gaccagctcc cgaacctctc tctgatagcg ttggaaatgg tttcgaatca ccgcatgagt
     4441 tcgcccgtct aaaattgcga ggatggattt ggactcaaaa tcttgggcaa tgaagctcat
     4501 tttgctcttt ttgaagctat actcatccca actcataact tttggcaact tggtccaatc
     4561 ggtttcaaac ttaaattccc tcagttttcg gatgacggtg gaagttgaga ccgccaatct
     4621 gtgggcaatc tcagtcatag actgcttttc aaggaggagc tgagcgattt tttgtctcac
     4681 catgttggaa atctggcaat ttttcttgac aatggatgtt tgagaaacga ccaccttaag
     4741 gcaattcttg cactgaaagc ggcgcttttt gagatgcagt accgtgggta aaccctgaca
     4801 gtcgagaagc ggaattttag aggctttctg gaagtcgtat ttgatcatct tcccttgaca
     4861 atgaggacaa ggaggagcgg gggaatccaa ctttgcctga acgactagat gggtttggta
     4921 tttcagaaca gacaagattt tgatattttt gtcttccaat ccgagcaaat ctgtggtatt
     4981 cttaagttgt tccatatgaa ccctttctaa tgagttggtt agacgctttt cattataggt
     5041 catatggggc tttttttcta caagaaacga ccctataatt cctggggtgg gattacccac
     5101 tacagaaatt atagagccaa aacattccaa agtcttgtct gactctggaa tgttttctgt
     5161 tcacagttgt tttgtaactg cctaataagt aaccgcgcta taacgaggta tctaccgaga
     5221 ttgtcaattc tccagtatac tgttataaaa aacaaaactg gaggattttt ttatgtcccc
     5281 ccatcgtccc atcgactgtt ccgtaactgc ccaataacgg agtatagtcg gctgaaacaa
     5341 gaataggaca aaagtgcctc aagaaaagca tcgtaatttg acaatattat tctgagatgt
     5401 ttttgatgta agcccatatt ttctcaatgg gattatactc gggtgaatag gtaggaagtg
     5461 gtaacagtct atgccctgct ccttacacat gttcattctg tgaaaccttg cattgtccat
     5521 aatgataagg gatggtgtat ctaaagtagg tagtaagaat ttttggaagc aagcttcgaa
     5581 aaagtcactc gtcatcgtat ctttataggt catcggagcc atagtatatt gaaacaaaaa
     5641 agggcattag tacttctata acagtatcgc aatctctggt gtgcgttgtc tcgatcttaa
     5701 ttcaaataat tatatcttct tccagagaga ctaactgcct gctcaaggct cgatcatatt
     5761 cgagataaaa ataggtctca acccctgtct cataaatata aataggagtc aggtagctta
     5821 agtgattcaa ttctttaagg aaccgattta ctttttctgg gtcttgttcg cagtaggtac
     5881 ggctcttttt tagactatat cccatagcct ttagagcgta atgaatagtt gttggaggac
     5941 agttgaattc agcagctatt tcagtcaaat aagcatcggg atgagtttca atatagatct
     6001 ttaatttatc tctatcaact ttttcaatta atagtggaag ttttcttgaa gttagtgtat
     6061 tgaaacgttt ttatacagtg ctaaaatttg aagtgtagtg cagatgtatt tgtaatagta
     6121 ttatagcaat tctttggaga aggtcgagac aagagaaaat aggtatcttt gagatataag
     6181 catgatttac tataaaatta ttgagttatt cataaaaatt tctctatcaa atatcataat
     6241 gcgtcgttta aggagatggt tacaatgcaa tatagttgtg gaaaaataaa tattaatatc
     6301 cctgatggat atggagacat taaggatata gtgttttcgg ctcatattat agttaggtat
     6361 aataatggac attgtggagg tatagatccg catataattg gactttgtaa aaagcagatc
     6421 agaaggatgt ctctatatcc tattttgata atcgtatcta gagattcaaa ggttattgat
     6481 gattataaaa atttagatat tgcctatgtt gattgtactc aatgttcaaa taattttgaa
     6541 actgccttac acgttaaaaa tattttaaaa ttattaaaaa tccaacttat acactgtcat
     6601 ggctactcaa ctaattattt tttatatatg ttaaaaaaac ttgacaagaa tggatttgga
     6661 aaggttaaga cagtgataac atgccatgga tgggttgaat ataacttaaa aaagaaattc
     6721 ttgacttatt ttgatttttg gacatattct atgggagatg cttttatttg tgtatctgaa
     6781 actatgaaaa aaagattgga gagtataata aaaaataaga agatagttgc aataaataac
     6841 ggaattaatg tatcaaatag cgatttagat gtagtaggtg ttcaagactt taaaaaagaa
     6901 ttttgtattc caaataacaa aaaaatcatt tgttatgttg gaaggttgga tccagaaaaa
     6961 aggccggata gattccttga atttgcagaa aaattatttt tagtcagaga agatgtgatt
     7021 tttattatgg ctggaaatgg tagtatgtgg gctgctttga aagaaaaaat ttgccatttg
     7081 aaatgtagag ataatttcag gttacttggt gaaatctatc cagctactat agtttaccaa
     7141 atatcggatt tattgtatat ttcttctgat acagaaggaa tacctatgtg tgttttagag
     7201 tcaatgtcac aaggaacttc ggttttagct agtaatgttg gcgggttaag tgaaattatt
     7261 gaacataggg ttgatggatt tttatttgag aaggaagatg ttgagggagt gtgtgcttgt
     7321 gctaattttt tactcaatga ttctgagtat ttgaaatata taggtgagaa tagtaaatca
     7381 aaaataagaa aacatttttc tgtgcaaaaa atgtttgtag aaaccatgag agtatatgat
     7441 gaattattag agaagagtag tcatggatag gaatatagat caagaattag taagtattat
     7501 aataccaaca cataataggt atgaatctct gattagagct gtgaaaactt gtttacatca
     7561 aagttataaa aatatcgaag ttataattat tgatgataat tatagtaatg taaatttaag
     7621 aaataaaatt atccatcaat ttggctatac caatcataga attaagttaa ttttaagtaa
     7681 tgaagattta ggtgcaacta atgccagaaa cataggtatc aaaaattcta gaggtaagta
     7741 tatatcattt ttagacgatg atgatgaata tatgccagat cgaattttaa agttgatggc
     7801 ttgttttaaa aagagtagaa tgaagaattt agctttagtt tatagttatg gaataataat
     7861 ttatccaaat ggtacacgag aagaggagaa gaccgatttt gttggaaatc ccttgtttgt
     7921 tcaaatggtt cacatcagga cggtgttgtt ttattaaaac tacttgctca aggataccaa
     7981 attgatatag tgcgagaatt cttggtgaat tactacgctc acagtaaaga aaacggtatc
     8041 actggagtga cacaaaaaac aattaatgca gatgaagaat attataatta ctgtaggaaa
     8101 tattttaatt tattgagttt caacgagaga atattggtta caaagaaata ttattcttta
     8161 aacataaagc ggttactatt aataggagac aaatgcaagg ctttaaaagt aatcaagaag
     8221 gcaagagaag aaaaaatttt taacgaattt cttttttgaa atatatgtta ttatatcatt
     8281 ttggtttttt ctattgtata tatgacaact atgttcaatt aaaatttaga aagtgagaaa
     8341 ctattgtgta tactattata aaatcaaata taaaaaaatt tagtttatta acgatattta
     8401 ttgttgctgg tcaattattg ctaatttatg cagcaactat taatgctctg gtgttgaatg
     8461 aattaattgc gatgaattta gagcggtttt tgaaattgtc aatctaccaa atgattgtct
     8521 ggtgtgggat aatattcctt gactgggtag tgaaaaatta tcaggttgaa gtgatccaag
     8581 agtttaatct agagattcga aatagaattg ccacagacat ctctaactct acctatcaag
     8641 aatttcatag taaatcatca ggaacatatc tttcgtggct aaataatgat gttcagactt
     8701 taaatgatca ggcttttaaa caactttttt tagtaataaa aggaatttct ggtactatat
     8761 ttgcagttgt gactcttaat cactatcatt ggtcattgac tgtagccacc ttgttttcat
     8821 taatgattat gctacttgta ccaaaaatct ttgcatcgaa aatgcgagaa gttagtctaa
     8881 atttaactaa ccaaaatgaa gcttttttaa aatctagtga gactatattg aatggatttg
     8941 atgtgttagc gtccttgaat cttttatatg tattgcctaa gaaaattaaa gaagcaggaa
     9001 ttttattaaa gatggttata caaagaaaga caactgtaga aacgttagca ggcgctatta
     9061 gcttctttct caatattttt tttcagatat ctctcgtttt tttaacaggc tatcttgcaa
     9121 taaaaggaat agtgaaaatt ggtactattg aagcaatagg agcactaaca ggtgttattt
     9181 ttacagcgct aggtgaatta ggaggtcaat tatcctctat tattggtacg aagcctattt
     9241 ttttaaaatt gtattcaatt aatccaattg agtcaaataa aatgaatgat atcgaaccaa
     9301 atgaggtgaa tagagatttt ccgttatatg aagcaaaaaa tatttgctat aagtatggag
     9361 ataaagaaat attaaaaaac ttaaattttt gttttcaacg taatgaaaag tatttaattt
     9421 taggtgaaag tggaagcggg aaatctacat tattaaaatt attgaatggc tttttgagag
     9481 attatagtgg agaattgcga ttctgcgggg atgatataaa aaaacctcct atttaaatat
     9541 ggtttcgaat gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga
     9601 taatatttta ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt
     9661 tggtttgagt gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg
     9721 gagattactg tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa
     9781 taagaaaata gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc
     9841 gattgaacgt aagatattag atagagagga tttgactgtc attattgtta cccatgctcc
     9901 gcatccggaa cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta
     9961 agaatatagg ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag
    10021 agaaaaaagt atactttaat gatattgagt tagaagttaa gtattcctct gtcgaagaat
    10081 tgtttataat atgtgagaaa ttattagata agaaaaaagt atcatttttt tatgtagatg
    10141 agaaaccctt aaggtatctg ttatttgact atatatttcc actagttcta gctaaaaaaa
    10201 aatatcccaa tcttagatgg agtttccaat aagcaagttg ctccaacgtt gctgcatcac
    10261 ttttctttgg aaattgaaaa gaattttatc gatttttgct ataaaaatat ggatctcatc
    10321 ctaaaaactc aaagtatatc tttgtgtcat agagaagagc ttattattgt agatgtttca
    10381 gatgactcta aatttggtgt tttttacaag cgttttagaa cactggttga taaaaataac
    10441 ggaaaatatg tttgtgttta taatttcagt cgtgtttcag atatactgca aaactggaaa
    10501 aattattgca atcgaaaatt ttcggttacg tttactgaaa gccaatttga attatttaag
    10561 cttttatata atcaaaaaaa ttttaaaaca atttcgttgc tatttggaaa aaaattgttg
    10621 ctggaggaat tatctattat agcgatctta ctaatataga atacttttgt attttttggt
    10681 gggatagtat gtttgggaaa gattctattg gaaaatacgt atatgtagaa gagattagta
    10741 gatgtcattt tttagataga aattattctt tttgttatgg tttacaagat tataaaagta
    10801 aacttattaa atatttttta gaatagttaa tctattcgag agagataaag aaatatggaa
    10861 aatactttat tgaatatcac aggaagcttc gatatggaaa ctaggaatct aattagttat
    10921 tctttaactg atatctttga aacagataaa ataagaattg aacttcttgg agaaatttat
    10981 tataaaaata taaagttgga attgcatgaa ttcgctggat tgtataagat ttatggaatt
    11041 agcttaataa agaatattac cggaatgttt ttaattataa tttttgatac gaagacaaaa
    11101 gaattaaaaa tttttcaaga tataacgact tcatacttta atttatacta tactgtttat
    11161 ggaggtgtgt tctatatata gtacatcttt aaagaaagtg atgaagttat ctcatgttcc
    11221 cgttacctta aataacaaaa aaatacaaga atttatgaga aatggattta ttttagattc
    11281 aaatacttta gtaaccgaaa ttaataaatt agaatatttc tcttacattt ctgtaaataa
    11341 tactattcgt atatgtggta ttgattataa tgattcaaac aattttacta aagaacaagt
    11401 attaaagaat tgggactcta tgctacgtga atctatatta agagtgtata gtgaagcagg
    11461 agaggctaat attacactat catctggttt tgattcaaat tatatattat atacattagc
    11521 gaattatacg aattcttcaa ttaatgcatt ttgcatagga ggagaaaaag gaattaatga
    11581 gattcctgaa gtaactaaaa ttgcaaaatt ttatggtata aatttattag ttgatactgt
    11641 aatgagccaa gatttagaa
//
LOCUS       DAVDFK010000047        11560 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.47, whole genome shotgun sequence.
ACCESSION   DAVDFK010000047 DAVDFK010000000
VERSION     DAVDFK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.47"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..275
                     /locus_tag="VUR04_001759"
     CDS             <1..275
                     /locus_tag="VUR04_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341615.1"
                     /translation="EKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAK
                     LEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(272..481)
                     /locus_tag="VUR04_001760"
                     /pseudo
     CDS             complement(272..481)
                     /locus_tag="VUR04_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(484..794)
                     /locus_tag="VUR04_001761"
                     /pseudo
     CDS             complement(484..794)
                     /locus_tag="VUR04_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
     gene            complement(781..975)
                     /locus_tag="VUR04_001762"
     CDS             complement(781..975)
                     /locus_tag="VUR04_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341616.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1041..1391)
                     /gene="tnpB"
                     /locus_tag="VUR04_001763"
     CDS             complement(1041..1391)
                     /gene="tnpB"
                     /locus_tag="VUR04_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET5341617.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINSSESCDFY"
     gene            complement(1372..1557)
                     /locus_tag="VUR04_001764"
     CDS             complement(1372..1557)
                     /locus_tag="VUR04_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341618.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(1861..3423)
                     /gene="guaA"
                     /locus_tag="VUR04_001765"
     CDS             complement(1861..3423)
                     /gene="guaA"
                     /locus_tag="VUR04_001765"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET5341619.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3565..4263
                     /locus_tag="VUR04_001766"
     CDS             3565..4263
                     /locus_tag="VUR04_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5341620.1"
                     /translation="MLPAYIKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4306..5202)
                     /locus_tag="VUR04_001767"
     CDS             complement(4306..5202)
                     /locus_tag="VUR04_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET5341621.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5211..6146)
                     /locus_tag="VUR04_001768"
     CDS             complement(5211..6146)
                     /locus_tag="VUR04_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET5341622.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAKWILDRNQVMNLIRKEE"
     gene            complement(6143..6868)
                     /locus_tag="VUR04_001769"
     CDS             complement(6143..6868)
                     /locus_tag="VUR04_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET5341623.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMFKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(6952..7587)
                     /locus_tag="VUR04_001770"
     CDS             complement(6952..7587)
                     /locus_tag="VUR04_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET5341624.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7589..8416)
                     /locus_tag="VUR04_001771"
     CDS             complement(7589..8416)
                     /locus_tag="VUR04_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5341625.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRTCQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8625..8774)
                     /locus_tag="VUR04_001772"
     CDS             complement(8625..8774)
                     /locus_tag="VUR04_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341626.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KVHPT"
     gene            complement(8775..9503)
                     /locus_tag="VUR04_001773"
                     /pseudo
     CDS             complement(8775..9503)
                     /locus_tag="VUR04_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10026..10637
                     /locus_tag="VUR04_001774"
     CDS             10026..10637
                     /locus_tag="VUR04_001774"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET5341627.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10682..11410
                     /gene="rlmB"
                     /locus_tag="VUR04_001775"
     CDS             10682..11410
                     /gene="rlmB"
                     /locus_tag="VUR04_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET5341628.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
BASE COUNT         3504 a         2555 c         2088 g         3413 t
ORIGIN      
        1 cagagaaatt tttcggactt attgaggaca atcttaagca ggttcatcct ctttttcaga
       61 ctgtctttaa aacctttcta aaggacaaag agaaaatcgt caacgccctt caactaccct
      121 attcaaacgc caaattggaa gcgaccaata atctcatcaa acttatcaag cgcaatgcct
      181 ttggttttcg gaactttgaa aacttcaaaa aacggatttt tatcgccctg aatatcaaaa
      241 aagaaaggac aaaatttgtc ctttctcgag cttagctttt tttcaaccca ctacagttga
      301 caaagagccg gaattcttgt actactaaac cactccgacg ctgatcatgg tggtaaagcg
      361 tgattgcttg attctcagct ttcccagaca aaaaggtcca atagtaggtc agctgactat
      421 cactctctag caccctataa gaagtttcat ctgcatgaag taaggactga gtcaatagtc
      481 tcgttataaa ggggctttag gaataggagc tttcacaatt ttatcactcg gatttttatc
      541 actgcatgct tggcatttgt aagcgtgttg gatatgatct atgcgtttta attgcgcagg
      601 aataaagact aattctattc ttgtcgttga agggttgctc caatctcttt tagatctccc
      661 tgacaatcag agcaaatgct ctcttctact tgatgatgaa cttcttctga atcaaattgg
      721 gcaagaagag cttggcgttt ccctttagat ttcttacgtt tgtaggtaat ttcctctgtt
      781 tcaactggga acatctccat cttcctcaga tggagactct tcctcaaaaa ggttaagttg
      841 tccagagggg caaacacttt tctcagagga ttttccatag agcttttgag tcagataagc
      901 cacttgttca cgaagaaggg caagttcatt ggtgagacta tcaattgtag cactctgttg
      961 ttgaatgatt ttcaatcttc ttccatgggc ttcccctcct tgttttctac ctttattata
     1021 ctaaaaagaa agtcctcatt tcaatagaaa tcacaacttt ctgatgaatt tattttggga
     1081 gtgatagaaa agcccttcat cagccaatct acttgttcag gtgtgagagc tttgacatcc
     1141 ttttctgtac tgggccaagt cagtctgccg ttctcaaagc gtttatatag tagccaaaat
     1201 ccttgaccat cccagtaaag ggctttaaag cggtatttac gtccaccaca aaagagaaaa
     1261 acttgaccgg agaaaggatc caattcaaag tgggttttaa cgagataagc cagtgaatcg
     1321 attccttgtc tcatatcagt cttcccacac acgagataga cctgccctag gctagataga
     1381 tgaattgtca tagagcaaca ccttatccaa aagctgttct atcatttcga gattgagaga
     1441 ttgaaaaaaa cttacttcaa gcttgccaat acgaatttta agcagaatat catttctctt
     1501 tttagaatca aaacgacgag attgtggaat ctctacagga acaataggtt gtggcattaa
     1561 aatatcctcc aatagtttta ctttactaat agtatacagg aggagctcca tgaatgatag
     1621 ataccttgtt atgacgcgct taccatatta gaaagttggc tctctaatta aattaattct
     1681 cattatatat atcaaaagac cgcagcttga aaactacggt ctaatttttt gtccaaatgt
     1741 aaaccacttg gaactattat tcaatttatt ctttttagca aatgttcccg ttttaatccc
     1801 agttacagtt tttaatcctc tgtaaccgtt gattttacaa agcttttaat ttttttgcga
     1861 ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga tacggttaac
     1921 atgatccact tcatttacga tacgtactga gattttttga agtacttccc atggaatttt
     1981 ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa tcgtgtagtc
     2041 atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa cagtgaagta
     2101 ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa tagcgtctga
     2161 ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga tagcaagtcc
     2221 tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct ctgtaccaag
     2281 agcacgaact tcatccttgt aaagagtatt aagtggttca atcaattcaa actgcatatc
     2341 ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga
     2401 ctcgataaca tctgtatata aagtaccttg agcaaggaat ttcacatctt tgagcttgct
     2461 tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt tttgttcagg
     2521 gtcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt
     2581 caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt tacgaagaag
     2641 accgtggtct acgaagatac agatcaattg atcgccaatc gctttttgga gaagaacccc
     2701 aacgacagat gagtcaacac cacctgatag accaaggagg acacgtttat caccgacggt
     2761 ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt cacctttagc
     2821 cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag aatgacgaac
     2881 ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg
     2941 gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc
     3001 atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg atggtgtgtg
     3061 agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa caacttttcc
     3121 tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg gaattccgag
     3181 ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat ttggaccacc
     3241 tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa ttttatggct
     3301 ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct ggttgtactg
     3361 gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg aaatgttgct
     3421 catctttttc ctttctcaaa agaaatatct tttcccaata ttctatcaca aataagggcg
     3481 aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt acaatagaga
     3541 aaagatagaa atgaagtgaa aaatatgcta cctgcttata taaaaatcca tgatcagata
     3601 aaaaaggata ttgacgagta ccgttgggct attggtgaga ggcttcccag tgaaagagat
     3661 ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc tctattagtc
     3721 gaagaaggcg tcttagagcg ccgtgtagga agcggcacct ttgtttccag tactcgagta
     3781 caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca aggtaaagtt
     3841 ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga agttgccaag
     3901 ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta tgccgaccaa
     3961 gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa
     4021 gaagaaatca ccagtcattt cttccaaacc ttgcaaaaac atggctatcg tatcggcaaa
     4081 tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta tttggaagtt
     4141 gaaaaaggac atgctattct tggattgacc caggtttcct acctagaaga tggtactgct
     4201 tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct tgaaaataat
     4261 tagattacca cgcaaaaact ctctgtcacg gacaaagagt cttttttatt tttctaagaa
     4321 taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac caagaaaatc
     4381 aatgggataa aattgttcat tcattattaa gaaggcaaag aaaatcgccg atattggctc
     4441 aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt taaggaaagc
     4501 tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga gaaaatcaag
     4561 actagtcggg atatcggcct gtagaacccc tgtaaaagga agggcgacca aacctgctat
     4621 gaccattccc acaccaatga ccaagctgct cccccacttt ttaatcaagg ctatgggtaa
     4681 aatgatatac agagcataag tcaaggcaga aaagagaccc cagaacagac cagcaggtgt
     4741 catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa
     4801 tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac agctataaat
     4861 taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat tggtctcctg
     4921 aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa aaataagaag
     4981 agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg cagtagcata
     5041 agccaagagc atgagaattc caccagcgat taaaagacgc aagttagtca agaccagagc
     5101 cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc aagcaatacc
     5161 agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc ttactcttct
     5221 ttgcgaatca agttcatcac ttgattgcgg tctaatatcc atttagctct ctcgtccttt
     5281 tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt ccacatgata
     5341 aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca tgctaaagaa
     5401 cgttccttgt catccaaagg agaaaaattt tgatttaagt ctcttgcaaa atcatctgct
     5461 aaatagtgtt ctaaaaagat ttgtaaatcc tttatagtcg aaaataaacc agcactccca
     5521 gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc tacacctcta
     5581 actgttggaa cagcaagctc aactggccca aacttagttt ccgtcattcc ccaaggtttc
     5641 cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc caaaataaag
     5701 cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg tctgttgaga
     5761 tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg aataaaagga
     5821 tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata atcactctca
     5881 ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca caagaaggta
     5941 caaactgtgc caaccccaac aaccttgctg acactagcta ggtcataaac tagtcctgcc
     6001 tcagtctgca agccatgctc tggggcactc tggcctaaat agaactctgt ccattgattg
     6061 tccttaaaat acgcaaaaga ggctccggga taaattcctg cctcgatttg ttcttctatt
     6121 tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca ttatttctat
     6181 ctttaccaag gaagaatttt tcagacttag gaataaaata ttcagtagac tcaaacttct
     6241 ggcgaagact tgctatgtct aattcattga ccaagaactt gaacatagat aagtcccagg
     6301 taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca agggatgccc
     6361 caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat tccatagaaa
     6421 tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc ttttctccta
     6481 cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca tcttctggtg
     6541 agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc gaatctgttt
     6601 tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat ctagctagtt
     6661 tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa accagctttt
     6721 caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag gccttcattc
     6781 caagggtttc aatataaaat gtttcattta attttctatt attagctttt aaagtaggaa
     6841 taatccgtac aatctgattt acattcataa attcctccgt cactttttat tttaaaggat
     6901 tttagaattt tttacaagat attatgctca aatttaacat tatttagcta tttagtaaag
     6961 atagtctttc aaggattttg acaaagcctg ataaccagca atactgaggt gcagtccatc
     7021 agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa atactggcac
     7081 aaattccacc tgcatatagg cagatgcaag ctcttgatag gcttgattcc agttctgaat
     7141 tttttcattc gagcggatat agactgcctg ctggtactcc tctccctcat tgacaggcaa
     7201 aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc
     7261 ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat ttgtcccaat
     7321 cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaaggt tctctagtaa
     7381 cagtcctgtc tgatagccac gaattcctcg attgacaatc gtctttgaag tcccaaatag
     7441 ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt ttggttctac
     7501 aacagaaatg tgatttaggt gacgatactt ggtttgaatt ttttcttgtt cctttaggag
     7561 ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag ttttccaaga
     7621 cttgataaac tcctccttgg ctgttggctg gtgctagagc agtcgccaca gctttggctt
     7681 tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt tcaacatcat
     7741 tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc ttgagtaatt
     7801 cctccaagcc ccatgcttta tgaatcccag cttggaggat atcaatgcaa ccatagccac
     7861 tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa accgaactca
     7921 aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg tcagatgtta
     7981 attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga gtcataaaac
     8041 tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc cccgttacaa
     8101 caaactggtc ctgacacgtt cgacccttga aatgagccaa agccttgttg acaatggcgt
     8161 catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg ccattagcaa
     8221 caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg tgaatttcat
     8281 tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa atcttttcca
     8341 atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata tctgtcgcaa
     8401 ttaccttaat catcatttac tttcctctgg attcaagcta ataccacttc aatcccacat
     8461 gttcattcat ttctttatag actgtatcaa ttcgttcctt agtcgcttca tctaactggt
     8521 cacgatgact gccacccctc tataaaatct tccaaaatat aagtttggta atgatacaag
     8581 ggatatcctt ctggtgaaaa ggttcccttt gatgttcgat tgacctaagt aggatgaact
     8641 ttagctgttc cgatagttgt ttttccatcc ttcttcttga tggtgacatc catgagaaca
     8701 ccacgttcag tccacttagc attctcttca tctcccatag attcaatccg ttgattggaa
     8761 atgaagttcc ccatttaata gacaatgagc ttcttatctc catctttttc caccgtttca
     8821 gatggttcaa caacgtgagg atgccctcca aagataatat ccgctcccca atcgatcatc
     8881 ttgtgataaa gagctttttg ttcttcagtt ggttccaatc gatactcaac acccatctga
     8941 ggcatgataa tggtgatatc ttcttccttc tctgcccgtt caacttcagc ctttatctta
     9001 tcttcgttta aatctgaaag ataacgatta tagtcttcct gagaaatata ctgctcaatt
     9061 ccattgaaac cataggaata ggctaacaat gcaaccttga taccattcac ttccttaatg
     9121 agcaacggag cctgatcacg tggttcgtgc gtataaactc cgattggagt gattccagct
     9181 ttctcaataa tatcggccgt tgaaataact ccctcaattt gcgaatccaa aatatgatta
     9241 tgagctaaat ccagcacatg ataacctgcc tccttaatag catccataac ttcaacagga
     9301 gcattaaaga gaagataacc cgctaaataa tgatccttat taatggttcc ttcaaaatca
     9361 ccaatagcta aatctgctgc ttagtcccct tgcttgagcc aaggagtcac atactcaaaa
     9421 ttttcatgaa agtcataggt accgtcttct tttttagctg aaaagaaaag tccatcgtgg
     9481 tagagcaaat ccccgtgggc cataattctg gcagtttttt cctcttccta ctcctgagac
     9541 ttttgcttag tcccctcttg agaaatagta tctcgttttt gactagtcaa gggattcctt
     9601 ggaagctttc aaacaacaag accaagccca ttgataaacc aactgctagc aagagtatcg
     9661 ccacaaatcc cttattgctc cacttgcgat aactcctaaa aagtttacca agcccttcat
     9721 aaaacgaaaa gctaaaccac cctgatttcg attttgtctt ctttgtatct tcattctccc
     9781 tactttctta tgcaagcctt ttctttttat tatatcacag ataagtattt ctttcacaat
     9841 tgaattgaac ttcccatcta ttttctataa atcctaaatg ccataatgct ttcaattctt
     9901 gtcattttgt gatatcatgt agaggtaatg aaaggaaatg aactaatcca cagtggctta
     9961 ttccaagtat accacttggg ctttggcagt agctaactgc actaaacata atataaggag
    10021 agaaaatgtc tgcaatagaa cgtattacaa aagctgctca cttaattgat atgaacgata
    10081 ttatccgtga agggaatcct actctacgcg cgattgctga ggaagtcact ttccccctat
    10141 ctgaccagga aatcatccta ggcgaaaaga tgatgcaatt ccttaaacat tcccaagatc
    10201 ctgtcatggc tgaaaaaatg ggactccgcg gtggtgttgg actggctgct ccccagttag
    10261 atatctcaaa acgcattatc gctgttttgg tacctaatat tgttgaagaa ggcgaaactc
    10321 cacaggaagc ctacgatttg gaagccatta tgtacaatcc aaaaatcgtc tctcactctg
    10381 ttcaagatgc tgctcttggc gaaggagaag gttgcctgtc tgttgaccgt aacgtgcctg
    10441 gctatgttgt tcgccatgcc cgcgttactg ttgactactt tgacaaagat ggagaaaaac
    10501 accgtatcaa actcaaaggc tacaactcca ttgttgttca gcatgaaatt gaccacatta
    10561 acggtatcat gttttacgat cgcatcaatg aaaaagaccc atttgcagtt aaagatggtt
    10621 tactgattct tgaataaaga aaatcccgtt gcaagacggg gttttgtgtt ataatagagg
    10681 catgaaaaca aatgatattg tctatggtgt ccacgccgtt accgaagccc tccttgcaaa
    10741 tacaggaaac aaactctacc tccaagaaga tctccgaggt aagaatgttg agaaagtcaa
    10801 ggaactagct acagaaaaga aggtgtccat ttcttggaca tcaaaaaaat ctctctctga
    10861 gattactgaa ggtgctgttc atcaaggttt tgttctacga gtgtctgaat ttgcctatag
    10921 cgagctagat tacatccttg caaaaacacg ccaagaagaa aatccacttc tattgattct
    10981 agatggtcta accgatcccc ataatctggg ttctatcttg cgaacagccg atgcgaccaa
    11041 tgtttcaggt gtcatcattc ccaagcaccg tgctgtcgga gtaactcctg tcgttgccaa
    11101 aacagccaca ggtgctattg aacacgttcc aattgcccga gtgaccaacc tcagtcaaac
    11161 cttagataaa ctcaaggatg aaggtttctg gacctttgga acggatatga acggtactcc
    11221 ttgccacaag tggaatacaa aagggaaaat cgccctcatc attggaaatg aaggaaaagg
    11281 tatctctagc aacataaaaa aacaggtcga tgaaatgatt accattccga tgaatggaca
    11341 tgttcaaagc cttaatgcca gtgttgctgc ggccattctc atgtacgaag ttttccgaaa
    11401 tagactataa aaaagtttcc agtcatctga ttggaaactt ttggctctat aatatttgta
    11461 gtgggtaaat cccctatgga tattatggag cctattttgt gtagaaaaaa agtcccatat
    11521 gacctataat gaaaagcgac aaaacaactc attagaaaga
//
LOCUS       DAVDFK010000048        11434 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.48, whole genome shotgun sequence.
ACCESSION   DAVDFK010000048 DAVDFK010000000
VERSION     DAVDFK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.48"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(39..590)
                     /locus_tag="VUR04_001776"
     CDS             complement(39..590)
                     /locus_tag="VUR04_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341629.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNSASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(892..1710)
                     /gene="nadE"
                     /locus_tag="VUR04_001777"
     CDS             complement(892..1710)
                     /gene="nadE"
                     /locus_tag="VUR04_001777"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET5341630.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDF"
     gene            complement(1707..3167)
                     /locus_tag="VUR04_001778"
     CDS             complement(1707..3167)
                     /locus_tag="VUR04_001778"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET5341631.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3282..3770)
                     /locus_tag="VUR04_001779"
     CDS             complement(3282..3770)
                     /locus_tag="VUR04_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341632.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFCICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(3760..3969)
                     /locus_tag="VUR04_001780"
     CDS             complement(3760..3969)
                     /locus_tag="VUR04_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341633.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(4355..5083)
                     /locus_tag="VUR04_001781"
     CDS             complement(4355..5083)
                     /locus_tag="VUR04_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341634.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(5099..5891)
                     /locus_tag="VUR04_001782"
                     /pseudo
     CDS             complement(5099..5891)
                     /locus_tag="VUR04_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(6327..7055)
                     /locus_tag="VUR04_001783"
                     /pseudo
     CDS             complement(6327..7055)
                     /locus_tag="VUR04_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(7315..7626)
                     /locus_tag="VUR04_001784"
     CDS             complement(7315..7626)
                     /locus_tag="VUR04_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341635.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(7641..8927)
                     /locus_tag="VUR04_001785"
     CDS             complement(7641..8927)
                     /locus_tag="VUR04_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET5341636.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVNEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            9551..9733
                     /locus_tag="VUR04_001786"
     CDS             9551..9733
                     /locus_tag="VUR04_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET5341637.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            9743..10093
                     /locus_tag="VUR04_001787"
     CDS             9743..10093
                     /locus_tag="VUR04_001787"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET5341638.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKQG"
     gene            10101..11291
                     /locus_tag="VUR04_001788"
     CDS             10101..11291
                     /locus_tag="VUR04_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET5341639.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
BASE COUNT         3721 a         2264 c         1901 g         3548 t
ORIGIN      
        1 aataaatagt tgacttcgat agaaacagaa aatagaattc aacattcttc cctacttata
       61 ccataataaa taagatccgc aagatagcct tttctctcta caccattaac aatggtttgt
      121 agataggaca ttccagcctt ttccatgaca cgacctgaag ctgagttgag actggcataa
      181 cgtgctctga ccttttgaaa acctgcttga gtaaaacaaa agtccaagac agctttcaag
      241 gcctctgtca tcataccatg tccccagtaa gccttgccta gcacatagcc gatttcacag
      301 cttaaatcag cctcgtctat cttaacgatg ctgatatctc ctatcacttg ctctgggttt
      361 tcttttagac aaatggccca tttgtaatag ttgagattag tataggaagc aacccaattg
      421 cgaatcgagt ttcgagtgat ttcgacatca ggatggggat cccaggtaac ataggtcaga
      481 ttctcagcgg atgaagccca attttgaaac atggcttctg catcactctc cacaaatctt
      541 cttaaaatca aacgttctgt ctgtaatatt tgcgtaccaa tagatttcat gatgctacct
      601 cacttcctta tttctatgct cgtagtaaaa aggctcaact cagtaacagc tagaaaacga
      661 gtttgtcttc taatttcttg acgtagtcgc tgcctggttt gaaatgcgat ctagcaagct
      721 ttttcaaacc tagtcatcgt tgcaggggta aaacgatgaa atcgaactct tcgagttacc
      781 gaatctgcct cattttctta tttctaaact cgaggttcaa gatcccccgg accttcttcg
      841 ctttctcatt tctaggctca gggtaaaaac ctccagtgga ggtttttact ctcaaaagtc
      901 atcaaataca gtgatgggta agtggcgttt gtgttggcct ttgtgccacc agttttcaat
      961 ggtcgcttga gcttctgggc tgattgtttt gccttctagg tagtcgtcaa tctctgcgta
     1021 ggtgactcca agtgcgactt cgtcagctag gcctggttta tcttcttcta ggtctgccgt
     1081 tggaattttt tcataaaggg ctggctctgc gccaagtttc tgcaagagct gttttccttg
     1141 gcgtttattg aggcggtaaa gagggagaat atccgcaccg ccgtcaccaa acttggtaaa
     1201 gaaacctgtg atattttctg cggcgtggtc tgttccaatg accgctccgc tatgggaacc
     1261 agcaagggca tactgagcaa tcatacggca acgtgccttg atattcccct tgttgaagtc
     1321 tgaaacagga ctacctgtcg cttcaactgc agctgtcatg gcatcagctg attccttgat
     1381 attcacaacc aagctgacat ctggctggat gaaggctagg gctttttgag catctgcttc
     1441 atcagcttgc actccgtatg gcaggcggac agcgataaat ttgtagctat cgtctcccgt
     1501 ttcagctcgc agttcttcca tagctaattg cgccaaacgt cctgccaagg ttgagtcttg
     1561 tcccccagaa atccctagta caaaggtttt taggaaggga tgttttttca gatatctttt
     1621 taagaaatca atagaacgac ggatttcttc ctgggcatca atcactggtt tgacacccag
     1681 ctcttggata atcgtttctt gcaaactcat tcttcttctc cttcaccaag ggcttccttg
     1741 cgcatcttat caatcaagtc catcttatct tgccatacgt cacgcgccaa atccactgga
     1801 tagtgctgcg gattgagcac acgcttatac tcatcccaca acttgtcaaa ttccttacgg
     1861 gcataatcct gaatgtcagt caaactaggc aagttgtaaa ctaatattcc ttctttgaag
     1921 atatccacca agagaggaac ggcatcaaaa ttacgaaccg tcttcttgat gtatgtatag
     1981 gtcggatgga acatcttgat ttctgtcatg tcgctaatat ccacaccatc ataagtgatg
     2041 tagtcacctt ctgacttgcc tttttcacga ctggtaatgc gccacacctg cttcttacct
     2101 ggcgtcgaca ctttttccgc attattagac agcttaatcg tattgcgcat ctgtccgttt
     2161 tcatcttcga ttgcaacaat cttgtaaacc gccccaagag ccggctggtc ataggctgta
     2221 atcagcttgg tacccacacc ccagacatca atcttggcct tttgcatctt taggttaagg
     2281 atggtatttt catctagatc attagaagca taaatcttag cctctgtaaa tccagcctcg
     2341 tccagttgct gacggacttt cttagaaatg taggcaatat ccccagagtc aatccgcaca
     2401 cccataaagt taatctgatc acccagctca cgcgccacct gaatggcagc tggtacaccg
     2461 atgcgaaggg tgtcataggt atccacaaga aagacacaat ttttgtgggt cgcagcgtaa
     2521 gccttgaaag cttcatagtc atttccataa acctgtacca aggcatgggc atgggttccc
     2581 aaaacaggaa tgtcaaagag cttacccgca cgcacgttgc tggttccatt ggccccacca
     2641 atcaccgctg cgcgtgttcc ccagatggcc gcatccattt cttgagcccg acgtgtccca
     2701 aactccatca agggttcatc ttcgataacc gaacgaatac gagctgcctt cgtcgccacc
     2761 aaggtctggt agttgacgat gttcaaaaga gccgtttcga ccaactgaca ttgggctaga
     2821 ggtccttcca cctgcacaat cggttcatta gcaaaaacca aatccccttc ttgggcagaa
     2881 cgaacggtca actccaactt gaaattgcga aggtaatcca agaacgcccc atgataacca
     2941 agcgactcca aataggctat atcactatct gaaaaacgca agtcttcaag atagttcaca
     3001 attctttcca aacctgcaaa aaccgcatag ccgttcttaa aaggctgttg gcggaaatac
     3061 acctcaaaga ccgccttctt attgtgaatc ccttggtcaa agtaaacctg catcatgttg
     3121 atctggtaca agtccgtgtg caatgtcaaa ctatcatctg gatacatact ttcctacttc
     3181 cttagctaga aacccatgaa aattttcaag aactttcatg tattccaata aattagtact
     3241 attatatcac attttagctg gattgagaaa agagtaacaa gctattctcc actctccaat
     3301 tcatccatat cttgttcaaa ttttttctga gcccattcgc catagctctt aagaccaaga
     3361 ttgccaataa agacccacgg aaggtaaatg acataagtaa tgacccaagc agacaggtat
     3421 ttaaaattca aaggattgtg ctgataaatt tctatgttga attgataatt ctgcaacatc
     3481 aaaagagccg taatagccaa ggttaggaaa aaacaaccca aaatcgtaaa atgaaaacga
     3541 ctatagtagg tcactcccag ataacgggcg cgattgaaaa agtaaaatgt ccctatgatg
     3601 ataacgatta gcagcatatt agaattaaaa aggcttggtg ctaatactga aatgatataa
     3661 gataggagcg acaaagcaat gcagatacag aaactttcag agcccgcttt attgaacagt
     3721 tgttcttctc tttcgtctag taattgataa taataaaatc tatttttcat cttcttcctc
     3781 ccaaaatagt tggtctaggg ttttccctaa acatctgcaa atagactggc agagcgagag
     3841 actgggattg tattttcccg cctctatcaa accaatagtc tggcgtgtca ccccgacagc
     3901 ctctgccagt tgaccttgtg ttaaatcacg ctctacccga gctaatttta attttaaatt
     3961 tttagccacc ttcgtcctcc ctatagtttt aatactcatc tactcttaaa aaatccaaaa
     4021 ccaacacaag ctatcagcta tttattataa ccccattaat ttgcactcca gtattatctt
     4081 cagccgaaaa tcagtatttt aggttgtttg aaataaactt cctagtttac tcttttattt
     4141 ttatttagta ttagctttag tagaatcttt taaacgagtt tttattgctt atatttcttg
     4201 tttagtttag ttggtttcat atcactatta tataatgctt ttggaaatga gcctagtata
     4261 agtcaaaaac gtgttgaata gtgaaagcag gagcatacca agatgactga tttttttatt
     4321 gtattttagg tatgcaaaat aatactaaat gaaactaaaa tgaatacttc ttgcttttct
     4381 tgagagtgaa aaagtacaat aaaatgattg tagtgattac cacaagatac tgactaatag
     4441 acatcgtatt tgaagccaca aatacaggta aagaataaaa aggaagaagt tcaattgctt
     4501 tgataaacaa atcattacta gtattcatca tcatcgtatt taatatatta gggataaaga
     4561 gtagtaaagc tactaaaata ccaaatacca agccactttt caatttgtat aaatagaaaa
     4621 tgtaagataa tagaaaataa aacaggacta acaaaattgt attgactaca atagctacta
     4681 taaaatctaa tcctaaatca cctggaatac ccaatttact tactatgact agtaacacaa
     4741 tgccattcaa agcataaata atggaaactg agatggcata tagaaaatta gacaagacgt
     4801 aaatcatccg attcttctgt tgattataaa acaaacttac cgtattgtgg gaaaaatctc
     4861 tactaatgac tcgattagca tgtataacag ccattaacat accgagcata gcataaaagt
     4921 ttgaaatatg cttaatacca agcgatgtcc cttgagtctt tagaataaag aatgtaacca
     4981 atatcggcgg tataaacgag ataagcaaac cgagatatat tacgcctgat gaatataaat
     5041 ttcttatatt ttccttaaga aaattcaatt tatttaattt catgattata accttccttt
     5101 attttgaacg atttaggtaa atatctttaa gcgtctcttt tttagtttca aaatcaacta
     5161 ctttaataga gttttcgtta aaaaatttaa aaagctcact actttgaata ttcccagaca
     5221 tagtaattct caatccctct tcctgaacaa tatccccaaa ttcttgtttg gtaatgaaaa
     5281 tgtctctatc tgtagctgat gaaaaagcta tctcaaacaa gaaattatga ctatcttttc
     5341 ctactttttg aaatgtcaaa agcccgttct ccaagaaaag aactctctca caaatttctt
     5401 caatgtcttc taatttatga ctcgatatta aaattcccac attttcatgt aaagctaaat
     5461 tttttagaac cgctaaaact atttgtgatg attcaatatc taaaccatta gtcggttcat
     5521 ctaaaatcaa tatatcaggt tccgtaacga gagttagaag caaagctaat ttttgttttg
     5581 tacccaaaga aataggtctt tactttttta ttaatagact gagtcaaatc taactcttgg
     5641 atcaaacttc taaatatttc ttgattgtag tcaacaccat ataaatttga caaatatttt
     5701 aaattctcta aacctgtttt agataaaaat aattttggtt cttcgattaa atacccaaca
     5761 ttatcactgc ttataatatt acctgaagtc ggttgattat tctgaacaag aattttcatc
     5821 aacgtactct taccaactcc atttctccct gctagaccaa caatttcacc cttgttaagt
     5881 gcaaaattta tatctttgag aatgattgaa tgaccataat gcttacttac atttataact
     5941 tacatttttt attcctccat taatattcat ggtttgctct ttgattctta ttgagtttaa
     6001 aaagttgcgc ctctttttaa caatattata tcatatatct aacttaatgc aatatataaa
     6061 tgtcattttg taaaatttta ttaacaaaaa actctctaca acaaaataat agagagtttt
     6121 ctgcttatta atttttttca aaatatctaa gacatcgctt ctttgtttaa tttgatagac
     6181 tttaatacct aagctccgac tttatcactt aaaaaataaa aaaggacagc taatctcttg
     6241 cgcatcaagg gatttcgcca ttctttaatc tcgtttaagt gttgtatatg gagctttgca
     6301 taatttttta aaactaaaca actacattaa ggacgaactg tgacgctggt tccatcttcc
     6361 ttataaagat tgataagccc ctctttaaga gctcgaacca tgtctccagc ttgaacaggt
     6421 tgtgggactt taatagtcaa tagttccatt ggatttggag cgcggtcgat tttattgcct
     6481 ttggcatcat gcaaatcttc aatataggtt tcaaaatgac ggaaacctgg accataaaac
     6541 tcaacttggt ccccttcgtt aatgacgttt cgttgacgaa tagttgctgt ttgtgccgca
     6601 tcatcataag aaaccacttc agcgacaaac ttgtactcag ggattttacg acgagcacca
     6661 aacaactgct cattttcaga tggtgtacca tagtaaaatc ctgtagccag ttcacgttgg
     6721 gcaaccttcc acatctcgtc caccaagtct tgtttgatag cttcaaactt ttcaggactt
     6781 tcaagatagg catccacagc cgccttgtag cagttggtta ctgttgatac atagtgaata
     6841 gactccatac gtccttcgat ttttagactg tccacaccat tttcaatcat atctgagata
     6901 tggtcaatca tagacatatc aacggctgac attgaaaatt cttctggaat ctcaccctgc
     6961 aaactcttac gttctttccc aaatggcata tcgtaaaggt cgtacttcca acggcatgac
     7021 tgagaacatc caccacggtt ggcatcacgc atactctaga cggattgttt tgacaattct
     7081 aaccttttag actttgcata ataactgtta aacagtcgaa aattacccca gttttaacaa
     7141 gtagtcaaaa taccagataa agtaaaaagg ggctaggaaa aaagtcttta aaatcttaaa
     7201 aacgcatagt atcaggtatt gaacaatctt gatattatgc gttttattgt gggaagattt
     7261 acttcatttt ctcttggaat tgagttttct cctacttcaa aactagatga tttgctattt
     7321 aaaatagcgt tccttatgat tttggcaacc tggattaaag cgagaaaaac aaaagaggca
     7381 acttaagctt tctttatatt gcttatatgt taatagtttt agacaaacac cacataaaat
     7441 aggcttatcc tgtatcaaag ataagggata aggctcaaaa gggtgatttt ctaatgaatc
     7501 atgacaccga taacaagcat aatacttttt acaatcatag cattgtaaag caataatatc
     7561 cagcttgcta tggtaatgaa tgcatcttgt ttgcttatcc actaagaaac cctgtgcctc
     7621 tatcatttcc ttttcctttc ttaagctcga actgtgacgc tggttccatc ttccttataa
     7681 aaattgatga gtccttcttt taatgcacga accatgtctc ctgattgaac gggttgtggg
     7741 actttaatag tcaatagttc cattggattt ggagcgcggt cgattttatt gcctttggca
     7801 tcatgcaaat cttcaatata ggtttcaaaa tgacggaaac ctggaccata aaactcaact
     7861 tggtcccctt cgttaatgac gtttcgttga cgaatggttg ctgtttgtac cgcatcatca
     7921 taagaaacca cttcagcgac gaacttgtac tcaggaattt tacggcgagc accaaacaac
     7981 tgctcatttt cagatggtat accgtagtag aaacctgttg ccaattcacg ttgggcaacc
     8041 ttccacatct cgttcaccaa gtcttgtttg atagcttcaa acttttcagg actttcaaga
     8101 taggcatcca cagccgcctt gtagcagttg gttactgttg atacgtagtg aatagacttc
     8161 atacgtcctt cgatttttag actgtccaca ccattctcaa tcatatctgg aatgtggtca
     8221 atcatagaca tgtcaacggc tgacattgaa aattcttctg gaatctcacc ctgcaaactc
     8281 ttacgttctt tcccaaatgg catatcgtaa aggtcgtact tccaacgaca tgactgagaa
     8341 catccaccac ggttggcatc acgcatactc atgtggtttg aaagagtaca acgtccagag
     8401 tatgaaatac acatagctcc atggacaaag gcttcaattt caacatctgt acgtttgcgg
     8461 atttcagcta attcttccat tgaaacctca cgcgctaaaa cgacacgagt caagcctagc
     8521 tctttccaga actcaagggt ttcatagtta gtggcactgg cttgggtaga aaggtggatt
     8581 tcaagacctg gtgcttcagt agctgcaatc ataatcaagg ctgggtcaga tacgataact
     8641 gctgcaatcc cgatatcacg cagtttacgg aaccactcac cagcaccagc ttcatttcct
     8701 tcgtgcataa ccatattagc cgctacatag accttggcac catacttggc cgcaaactgc
     8761 acgccctctt ccatctgttc gaaagtaaag tttcccgcac ggctacgaag accataggcc
     8821 tgaccaccga taaagacagc atctgctcca tactgaacag ctacctttag cttctctaaa
     8881 gtccctgcag gtgataaaac ctcaggacgt tttaatgttt ttgtcatgat ttctcctatt
     8941 tgcaatataa aagtttgaca tttttccttc tcattttata gtaaataaag gataaaatca
     9001 agcctagacg gattgttttg acaattctaa tcttttagac tttgcataat aactattaaa
     9061 cagtcgaaaa ttaccccagt tttaacaagt agtcaaaaag tctaaaaaag taaaaaccag
     9121 tatcccaaga tactgactcg taaaaatata taaattagtc cttagatgac tactcccact
     9181 ctgttgctcc tataatggaa aaggattgat acagtctaga atatcgcttt tttatttatt
     9241 attctgatat aaaactgtta gaattgattt tttgttttat acccaaatat gaatagagac
     9301 gtagctaata agttgaataa catatttgga aaaatgagaa atagcaatat tactagaact
     9361 tttagaaaca atcaatattt aaaaagaaaa aagctcaaag aatttattaa accatgttat
     9421 aatagatata gctataattt tatttataac aagaggatag aaatgaccga attagaaaga
     9481 aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag ttcaagagag
     9541 agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag ttttaggtat
     9601 ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt ttttatacaa
     9661 atatgctggt tcatttttag aagaagctgc agtactatcc tttaacgaaa aatttggtac
     9721 agaaaatact taaaaagtta acattcctaa ttctgaaagt acaaaaccta agacttttga
     9781 aattgattgt ttagtcggag aaaaacacgc atacgaaata aaatggtggg atgcaactac
     9841 agatggagac catataacta aagaacacac tagaataaaa gttattcata acaaaggata
     9901 tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa aaattcagca
     9961 aactttagaa acattgtata acggtattgg agggaaatat tatggagatt ctgcctggga
    10021 acatttaaga gcagtgaccg gtattgattt acttagtatt ctaacagata ttgcaaataa
    10081 aaaacagggg taaaatcaaa atgacagtat taaaaggaga taacttagaa atattaaaaa
    10141 ctattgaatc ctcaagtatt gatttaatct atatggaccc tcctttcttt acacagaaaa
    10201 cccaaaaatt atctaataac aaaaatatta tgtattcatt cgaagatacg tggacttcga
    10261 ttgaggatta caaagaattt ttgtctgtaa gattagaaga atgcaaaaga gtgctaaaaa
    10321 atagtggcag tattttcgtt cattgtgata aaattgcaaa tcatcatatt agattaattt
    10381 tagataatat ctttggagca gatatgtttc aaagcgaaat tatatggaac tataaacggt
    10441 ggtctaattc aaaaaaggga ttattgaaca atcatcaaaa catttacttt tattcaaagt
    10501 caaaagattt taaatttaat acaattttta cagagtattc ttctactaca aatatcgacc
    10561 aaatactagt ggaacgaaaa cgagatggaa actctaaaac tatatataag gttgataata
    10621 atggtaacta tattctagca aaagagaaaa atggagttcc cctttcagat gtttggaata
    10681 taccatttct taatccaaaa gctaaagaaa gagtaggtta tcctacacaa aaacctattc
    10741 tgttattaga acaaattata aagattgcta ctgataaaaa tgatatagtt ttagacccgt
    10801 tctgtggaag tggaactact ttagtagcct ccaagatttt gaatagaaat tatatgggga
    10861 ttgatttatc tgaggaagct atcaatataa ctcagcaacg tctggaaaat gttataaaaa
    10921 caagttcaaa tttattgaat aaaggaatcg aagcatatag aaccaaaact gaggaagagg
    10981 aaaacattct taaattatta caggcaaaaa ttgttcaaag aaataaagga attgatggtt
    11041 ttttacctaa acattttcaa aaaaaaccga tacctataaa aattcaaaaa aataatgaat
    11101 gtctgaatga gagtatctct ttattacaga atgctataaa ctccaaaaaa cttgattttg
    11161 gagtagttat aaaaactcat tcagataatt tattatttga ttttgatacg attcctgaaa
    11221 atataatagt agttgaccat tttgaactta caatcgaaaa atggttaagt aaaagtcaac
    11281 agttactata gtttgcaaat tatttacaga aagaacaaaa aatgctctga aacactgatt
    11341 tcaaggcatt ttttgttagt ttaaaattac tcccattctt cttttccaaa cgtacaatat
    11401 atccaaaacc attcaaaata ctagattcta tttt
//
LOCUS       DAVDFK010000049        11312 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.49, whole genome shotgun sequence.
ACCESSION   DAVDFK010000049 DAVDFK010000000
VERSION     DAVDFK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.49"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            27..1176
                     /locus_tag="VUR04_001789"
                     /pseudo
     CDS             27..1176
                     /locus_tag="VUR04_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1304..1507)
                     /locus_tag="VUR04_001790"
     CDS             complement(1304..1507)
                     /locus_tag="VUR04_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341640.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1500..2582)
                     /locus_tag="VUR04_001791"
     CDS             complement(1500..2582)
                     /locus_tag="VUR04_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET5341641.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2708..3490)
                     /locus_tag="VUR04_001792"
     CDS             complement(2708..3490)
                     /locus_tag="VUR04_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET5341642.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVIVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3490..4833)
                     /locus_tag="VUR04_001793"
     CDS             complement(3490..4833)
                     /locus_tag="VUR04_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET5341643.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRYGEIYTTYKMILDAIRKVPT
                     ATVLLNGDSPLFYKPAIPNPVEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4932..6248)
                     /locus_tag="VUR04_001794"
     CDS             complement(4932..6248)
                     /locus_tag="VUR04_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET5341644.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6441..7667
                     /locus_tag="VUR04_001795"
     CDS             6441..7667
                     /locus_tag="VUR04_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET5341645.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGSGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELVILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7866..9440
                     /locus_tag="VUR04_001796"
     CDS             7866..9440
                     /locus_tag="VUR04_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5341646.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9703..10491
                     /gene="codY"
                     /locus_tag="VUR04_001797"
     CDS             9703..10491
                     /gene="codY"
                     /locus_tag="VUR04_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET5341647.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10491..11066
                     /locus_tag="VUR04_001798"
     CDS             10491..11066
                     /locus_tag="VUR04_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET5341648.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            11147..11232
                     /locus_tag="VUR04_001799"
     tRNA            11147..11232
                     /locus_tag="VUR04_001799"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11181..11183,aa:Leu,seq:aag)
BASE COUNT         3374 a         2114 c         2487 g         3337 t
ORIGIN      
        1 ggataaacaa ttctaatatt aggtacatga ttaaattgat tgatcgttac ggaatagagt
       61 tcgtcaaaaa aggaaaaaat cgttactatt ctcctgattt aaaacaagaa atgattaata
      121 aagtcttata tgaaggctgg actaaagata gagtttctct tgaatacggc ctcccaagtc
      181 gtacgatact tcttaactgg ctagcacaat acaggaaaaa cgggtatact attgttgaga
      241 aaacaagagg gagagtacct gagagcggag aatgccatcc taaaaaagtt aagagaactc
      301 cgattgaagg aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa ttaatgactg
      361 agttttcgtt agatcttctt ctaaaagcca ttaaactagc tcgttcgacc tactactatc
      421 acttgaaaca gctagataaa ccagataagg accaagagct taaagctgaa attcaatcca
      481 tctttatcga acacaaggga aattatggtt atcgtcggat ttatttagaa ctaagaaatc
      541 gtggttatct ggtaaatcat aaaagagttc aaggcttgat gaaagtactc aatttacaag
      601 ctaaaatgcg acagaaacga aaataaagga gacgttggta agaaggcaga gaatctcatt
      661 caaggccaat ttgaaggctc taaaacaatg gaaaagtgct acacagatgt gacagaattt
      721 gccattccag caagtactca aaagctttac ttatcaccag ttttagatgg ctttaacagc
      781 gaaattattg cttttaatct ttcttgttcg cctaatttag aacaagtaca aacaatgttg
      841 gaacaggcat tcacagagaa gcactacgag aatacgattc tccatagtga ccaaggctgg
      901 caataccaac acgattctta tcatcagttt cttgagggta agggaattca agcatccatg
      961 tcacgtaagg gtaacagccc agacaacggt aggatggaat ccttctttgg gattctgaaa
     1021 tcggaaatgt tttatggcta tgagaaaaca tttaaatcac ttaatcaatt ggaacaagct
     1081 attgtagact atattgatta ctacaacaat aaacgaatta aggtaaaact aaaaggactt
     1141 agccctgtgc aatacagaac taaatccttc agataaatta attgtctaac ttttgggggg
     1201 cagtacattt taacacttga taatatgcgt tttattgtgg gaagattttc ctcattttct
     1261 agtgaaattg aactttttct aacatctttt gatagatgac ttcttaatca attatcattt
     1321 ccattgttgt ttcttggggt ttcatccctt gtctttgata aaagcggaga gcaccctcgt
     1381 tatcattcca gacacttagg gttagattat tgcagccaat ttctttagca taatagcaga
     1441 aaaatgacaa taaaatagcc cctagatatt ttgaaaggaa agcatagggg ctatatagtt
     1501 taatcaaaat aaagcaaatc tttgctggtg cttgtaaaga ggtcgaagcc atccttggta
     1561 acaacaccgc agtcttcaat acgaacaccg actttaccag ggatatagat acctggttca
     1621 acagagaagc acatgccttc ttcgatgacc atgtcgtttc cttccatgat agatgggaat
     1681 tcatggacat ccataccgat accatgcccg agacggtggt tgaagtactc accataacca
     1741 gctttttcga tgacctcacg ggcagcgcgg tccacttcat gagcagtcac acctggcttg
     1801 ataaagtcaa gagcagcttg ttgggcttca agagtcaagt tgtaaatatc tttcttgaat
     1861 tggtctggtt tgccgacagc gactgtacga gtcatatctg acgcatagcc attgaccaga
     1921 acccccaggt caaagaggag aagagcatca ttttcaacct tattagctgc tggaatgccg
     1981 tgtggattcg cagcattatc accagtcaag accatggtat caaagctcat ttcgtaacct
     2041 tcacgtttca tggcaaagtc aatttgtgcg atgatatctg tctcagtctt atcaagagaa
     2101 atattgtcaa aaccaacatg aacagccttg tcagcataaa gacctgcaac catcattttt
     2161 tgcacttcat cagctgattt gatgaggcgc atgcgttgga tacgaggagt gaggttgtca
     2221 aactcagcag tctcaaaaac tgttttcaaa ccatggtatt tggtcaagat gagattgtca
     2281 aactcaacag cgacacgttt gaagtcaagt tgtggaagag catgtttgat tttttgccat
     2341 ggattttcag aatcgacata gcccactact gggaaggaaa cggtgctact tgcacgttct
     2401 acttcaagag ctgggacaaa gaggagaggt tcctgatccg ctaggacaaa gaggaacatt
     2461 tggcgttcat ggggatcact gtaaaaacca gtgaggtaat tgattgtgac ggggtcagat
     2521 acgacagcga cgtctagttt ttctgattca agatatgtta ggatttgttg taatttagac
     2581 atatgctacc ttctttctac ccctctattt tggcaaaaaa tgagagaaaa tgcaagggag
     2641 aagggtaaaa gaaaagacaa aaaactccga caagataacg gagttctttg atatcatttt
     2701 cctttgttta agaaaagtca gccttgcttt tgacgtcact gtactcttca gcgatttctt
     2761 ggctgaggat atcctcatag gcagggagtt ggatatcctg accatatttc ttcttgaggg
     2821 cagtagtaac taggcgataa gccagattgg cattacgaga gaggataggc ccgtggaagt
     2881 aggaaccaaa gacattctta taatgaaccc cttcaccgac cttttcttcg ttgtttccat
     2941 ttccatagac aacctgtccc agcggttttt ggtcatcaga gaggaaggta cggccttggt
     3001 gattttcaaa tccatagtag gtttcatcga aatcttcatt gtgaatcttg atgtcaccga
     3061 taaaacggtt attggtctgg ttgagcgtgt agtgtcccat gacccctagc ccttcgatac
     3121 gttttcctga agcttcaaca taatattgac ccaatagttg gaaaccaccg cagatagcca
     3181 gaactacacc gtcgttttgg atgtagttgt caatgctctc ttttttagca ggtaggtcgt
     3241 ctgcaatgat actttgttca aagtcttgac caccaccgaa aaaggcgatg tcgtagtgat
     3301 tttcatcaaa gtcatcatgg agagaaacga tgtcaacgat cacatgggct cccagttttt
     3361 cagccacata cttgagcatg aggatgtttc cattgtcccc gtaggtattc atgagatttc
     3421 cgtagaggtg ggcaatgttg agctgatagg ggtaattgcc atcttttgag gaaagtgaag
     3481 tataaaccat tagttcatct cctttctaac aatctgacga ctagccagca gttcacgaaa
     3541 ttccagcatg gcagtataag ttgccagaat ataggcatgc ttgcagtctt gattctcaat
     3601 ggtcttgaga acttgctcca gattactcgt ttcagtgatt ttctcagctg gatagccagt
     3661 cactcggagg cgacgagcga tttcagaatg acgaacaccg ccagcgttga tttcaggaat
     3721 gtccatgtca gtgatttgtt caaagtctgc atcccagatc cagctagtgt caattccatc
     3781 tgcatagttg gcattaagga ggacagatag gctaaatgga taaggtgcta gtttgatcat
     3841 ttcgatagct tgggttgcac cgactggatt tttaatcaag acaagggtac attctttgtc
     3901 accgatatga aaggtttctt ggcgtccaaa gacagcacgg ctcttgtcaa atccctgttt
     3961 gatgagttgc gaatcggcac ctaggaaacg ggcgatggcc acagcagcta gggcgttata
     4021 gatattatag agcccgccga tttggatacc gtattcttgg ccgtctatga caaagcgaga
     4081 gcgattgttg gtcaactcaa ccagttttgt caaacgatag tcgagatcag gacgtttgca
     4141 tccacaacct tcacagatat aggcacccaa gtttgcatag gtattatgct catatttgag
     4201 gatgccttgg cagtcaggac agaggattcc ttcggtatta tagtgagcca gctgggctgg
     4261 acctttctcc aagtcaaaac caaaatactc tacaggattt ggaatagctg gcttgtagaa
     4321 aagtggactg tctccattaa ggagaacagt ggcagtaggc accttacgaa tggcatccaa
     4381 aatcatcttg taagttgtgt aaatctcacc atagcggtcc atctggtcac ggaaaatatt
     4441 agtaataaca aataagcttg gctggatata gtcacagata cgagatagac tggcctcgtc
     4501 gatttctagg acggcaatat ttttcccagt tttagaagat ttggctgtta agaaggttgt
     4561 cgcaattcct gtaatcatgt tggcaccgct tgggttggtc agaacttgac cataaacttc
     4621 ttttaaaata ccgacagtga gggcagttgt caaggttttt ccgttggttc cagtgaccac
     4681 gacaatctcg tagttcttag ctaggttttg taaaatatct ttatcaaatt gaagggcgac
     4741 tttacctggg agcgtacttc cacggccaag acggcttaaa atgaagtggg aagaacgccc
     4801 agcaagaagg cccaaagtag tttttaagtt catgtttcta ttatatcata aaagaggaga
     4861 aagacagatt tgagattccg cagaagtaaa aacagcccaa agagggctgt tcgatacgat
     4921 taaatctcaa cttaaatcgc aaacaagtca ttcaagttct cagccaaggt tgggtgagtg
     4981 aagatttgtt ttgtgaagta agtgtaagga atcttgttgt ccatagcaac agtgatgatg
     5041 ttgatgattt cttgagaacc ttctgagaag atgcttgctc caagaatttc ttttgtttca
     5101 gtattgacaa cagctttgaa ggcaccgcga aggtctccat ttacgtgacc acgaggcatg
     5161 gctgcaacgg ggatttcctt aacagcgtat ggaagtttca aatcagctgc ttggctttca
     5221 gtcaaaccaa cttgtgaaag tgcaggtgtg atgaacatag tatttggcac attgagacgg
     5281 tcttcaagtg tgtagctgcc atctccagca aggtagctgt aaacaacacg gaagtcatca
     5341 agtgaaatgt aagtaaattg aaggccaccg ttgacatctc caactgcaaa gacaccagga
     5401 acgtttgttt gacagtgttt gtctacttta atagcaccac gttcagttag ttcaatatct
     5461 gtattttcaa gttgaagtgg ttctacattt ggtttgcgtc cagttgcgta gagaagggcg
     5521 tcgaaacggt aagtttcgtc ttcagttacg acaagcactt ggtcaccatc gtttttgatt
     5581 tcagtagtat ggatattttg aagcaattca atgccatctt cttccatgta ttgtttagca
     5641 agagctgcga tggaaggttc tgcacgagga aggaaagtat ccaaggcatc taggactgtg
     5701 accttgcttc caagtttgtt gtaaaggccg gcaaattcaa gaccgatatt tccgccacca
     5761 aggattccaa gtttttcagg taatttgtcc aagttttgga tacctgttga gtcaaagatg
     5821 tttttgcttg tagcaagtcc aggaattggc aagacgtttg aaacagcacc agtgttgatg
     5881 acgatagttt cagcagtcaa ttcttgtttt tcatcaccag cttggatttc gatgacttta
     5941 tttgaaagga agtgagcttc agcatcaaag atatcgacgc cagtaccagc aacagtcgta
     6001 tagtttttac cgttgaggcg accagtgatc gtgtttttag tagcaatcac ttcttcaaaa
     6061 gacaagtcct tttcagcagc aactagcaag gttttagttg ggatacaacc aatgttgata
     6121 caagttccac cgtacatagc cttgctgcgt tcaacgaggg caactttttt gccagctgaa
     6181 gccaatttac ctgctagtgt tttaccagct ttaccaaatc caataacaat taaatcgtat
     6241 gttaacattt atcttcctcc tattcgaatt tcattctagc acaagaaaaa aacttttgca
     6301 caattctgct acggaaaaga cagaaaaaga taaaaacgct ttccagacaa aaaactagta
     6361 attttttgac aagcttgata aactaaaatc ctatctattt ttatataaga aagaataaat
     6421 gttcgaaaat aggaggtttt atgaaatcga atcgttatat tattgccttt gctggggtca
     6481 ttttacactt aatgctgggt tcgacttatg cttggagtgt ttatcgtaac cctattattg
     6541 aaaaaacggg atgggatcag gcttctgttg ccttcgcctt tagtctagca atcttttgtt
     6601 tgggcttatc ggctgcattt atggggcgtt tggtagaaaa atttggtccg aaagtcatgg
     6661 ggagtctatc tgcttttcta tacgcaggtg gaaatatctt aacaggattt gcaatagacc
     6721 gtcaggaact gtggttgttg tatctagctt atggcatttt aggtgggctt ggtttgggat
     6781 caggctatat tacccctgtg tcaacgatta taaaatggtt tcctgataaa cgtggtctcg
     6841 caacaggttt agcgattatg gggtttggtt ttgcttcttt attgactagt cccatagcgc
     6901 aacacctcat cgcaggggta gggattgtag aaacttttta tattttagga gcaagttact
     6961 ttattatcat gctcctagct tcacaattca ttaagcgtcc aaatgagcaa gagcttgtaa
     7021 ttttatcttc ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg gctgcaaatc
     7081 aggctctaaa aagcaatcgg ttttatatgc tttggattat tttctttatc aacatagctt
     7141 gtggtttagg cttaatttca gcggcatcgc caatggcaca ggagatggct ggcttgtcta
     7201 caagtcatgc agcagtaatg gtgggtgttt tggggatttt caatggattt ggtcgcttgc
     7261 tctgggcgag tttgtctgac tatatcggtc gccctctaac ctttagtata ttactgcttg
     7321 tcaatctttt cttttctctc tcactttggc tctttacaga ttccgtttta tttgtagttg
     7381 ctatgtctat tttgatgact tgctatggag ctggtttttc tttgattcca gcttatctca
     7441 gtgatatttt tggaaccaag gaattggccg ctctgcatgg ttatatttta acagcttggg
     7501 caatggctgg tttagcggga cctattttat tagcagagac ttataaaatg gctcattcgt
     7561 acacacaaac cttgttcgtt tttctcattt tatacagtat cgccttggct ttgtcttatt
     7621 atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt tctgtagaaa
     7681 tggggctatc ttttgctctg gtcttgtgtt atactagata ggttgcaaag aaaacagtac
     7741 ttttcttttg tggaaaagaa gcaacacgat tttatatcta gttatatgaa aatacgtcat
     7801 aaaaagaaaa gtataaacta agccctatag ggtggcttcg caccaccttt agaaagaaga
     7861 ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt gctagcagaa attgaaaaag
     7921 ctggttttgt agaagctagt cctatccaag aacaaactat tcctttggcc cttgaaggca
     7981 aggatgttat cggtcaagct cagactggta caggaaaaac tgcagccttt ggcttgccta
     8041 cccttgaaaa aatccgtaca gaagaagcga ctatccaagc tttggtcatc gctccaactc
     8101 gtgaactagc tgtccaaagt caagaagaac tcttccgctt tggtcgtagt aagggagtca
     8161 aagtccgttc agtatatggc ggatcaagca ttgaaaaaca aattaaggct cttaaatctg
     8221 gtgcccatat cgtggtggga actccaggtc gcctcttgga cttgattaaa cgcaaggcct
     8281 tgaaattaca agacattgaa acccttatcc ttgacgaagc ggatgaaatg cttaacatgg
     8341 gcttccttga agacatcgaa gccattattt cccgtgtacc tgagaaccgt caaactttgc
     8401 ttttctcagc aactatgcca gatgccatca aacgtatcgg tgttcagttt atgaaagccc
     8461 ctgaacatgt caagattgcg gctaaggaat tgacaacaga attggttgac cagtactata
     8521 tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg tctcatggat gtggcacaac
     8581 cagaactcgc tattgtattt ggtcgtacca aacgccgtgt ggatgaattg actcgtggtt
     8641 tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga cctagaccaa aataaacgtc
     8701 ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt tttggttgcg acagacgttg
     8761 cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta caactacgat attccacaag
     8821 atcctgagag ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag tcaggtcaat
     8881 ctattacttt tgttgctcca aacgaaatgg gttaccttca aatcattgaa aacttgacta
     8941 agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa tcaaaaaaac
     9001 aggtagctct caagaaaatc gaacgtgatt ttgcagatga aaccattcgt gccaactttg
     9061 agaaatttgg taaggatgct cgcaaattgg ctgctgagtt tactccagaa gaattggcaa
     9121 tgtatatctt gagtctgaca gtccaagacc cagatagcct tccagaagtg gagattgcac
     9181 gtgaaaaacc actaccgttt aaaccatcag gtaatggttt cggtggtaaa gctaagggag
     9241 gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc aatggtcgcc
     9301 gtgatgagtt caaaaaagga agtcgtggca acgatcgttt tgataaggaa aaacgttacc
     9361 gtaaggataa taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc tttgttattc
     9421 gtaacaaggg cgataaataa gaaaaagcgg ttcaaaatga atcgcttttt atataaggag
     9481 accgaatgtg aaaagacaaa taaaattatt atattatctt ttataatgtt atgatacaca
     9541 aaaataggca acttgtcaat agaaaaggaa caatttaatt aaaaatattc tggtttttaa
     9601 ttaaattgta agtcaatgca agtcaataag gaattttcag ataattattg aaaaagagac
     9661 atttttatgt tataatgata gcgattaaat tcgaggtgaa aaatggcaca tttattagaa
     9721 aaaactagaa aaattacatc aattttgaaa cgctcagagg agcagttgca ggatgagctc
     9781 ccttacaacg ctattacgcg tcagttagcg gatattattc attgcaatgc ctgcattatc
     9841 aatagtaagg gacgtctgct tggctatttt atgcgttata aaacaaatac agatcgcgta
     9901 gagcaattct tccaaactaa gattttccca gatgactacg ttcaaggggc taatatgatt
     9961 tacgaaacag aagcaaactt gcctgttgag catgatatga gtattttccc tgttgagagt
    10021 agagatgatt ttccagatgg cttgacgact attgcaccga ttcatgtatc ggggattcgc
    10081 cttggttctt tgattatttg gcgtaatgat aaaaaattcg aagatgagga cttggttctt
    10141 gttgagattg ccagtaccgt tgttgggatt cagcttctta acttccaacg tgaagaagat
    10201 gagaaaaata ttcgtcgtcg tactgctgtc accatggcgg tcaataccct ttcttactcc
    10261 gaactccgtg ctgtttcagc aattttaggg gaattaaatg gaaatgaagg gaagttgact
    10321 gcgtcagtga ttgcagatcg tatcggaatc actcgctctg tgattgtcaa tgctcttcgt
    10381 aaacttgagt ctgcagggat tattgaaagt cgctcacttg gaatgaaggg aacctatctt
    10441 aaggtcttga tttcagatat ttttgaagaa gtgaagaaaa gagattacta atgacaaagg
    10501 ctttaatttc gattgattat acagaagatt ttgttgctga tagtgggaag ctgacagcag
    10561 gtgctccagc tcaggcgatt tcggatgcca ttagcaaggt aactcgatta gcttttgaac
    10621 gaggagatta tatcttcttt actattgatg ctcatgaaga aaacgattgt ttccatccgg
    10681 aaagtaagtt atttcctcct cataatctga ttgggacgag tggacggaat ttatatggag
    10741 atttggggat cttttatcaa gaacatggtt cagacagtcg tgtcttttgg atggataaac
    10801 gccattactc agctttttca gggactgacc tagatattcg tttgagagag cgtagagtgt
    10861 ctaccgttat cttaacaggt gtcttgacgg atatctgtgt cctacataca gctatagatg
    10921 cctataatct aggatatgac atcgagattg ttaaaccagc tgttgcttcc atctggcctg
    10981 aaaatcatca atttgcccta ggtcatttca aaaatacact cggagctaag ttagtagatg
    11041 aaaatctaaa tgaactttct gagtaacctg gttggtgaaa atgaaaaaat ttgaaaaaag
    11101 tgttgacaag catcccaaaa gttgatatac tagtaaagta atcgacgcgg ggatggcgga
    11161 attggcagac gcgcaggact aaggatcctg tgaccgcttt aggtcgtgag ggttcaagtc
    11221 cctctctccg cataggaaaa gagctagcta aagcggctct ttgtcaactg tagtgggttg
    11281 aaaaaaagct aagctcgaga aaggacaaat tt
//
LOCUS       DAVDFK010000050        10701 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.50, whole genome shotgun sequence.
ACCESSION   DAVDFK010000050 DAVDFK010000000
VERSION     DAVDFK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10701
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.50"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..571
                     /locus_tag="VUR04_001800"
                     /pseudo
     CDS             1..571
                     /locus_tag="VUR04_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            471..917
                     /locus_tag="VUR04_001801"
     CDS             471..917
                     /locus_tag="VUR04_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5341649.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFMRLFCLVLVSIDYINRLSETTD
                     KNWHKSGRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDGVGHSDSEVTTSIYTHATKNMKDEAINVLDKVMKKIF"
     gene            complement(1055..2359)
                     /gene="eno"
                     /locus_tag="VUR04_001802"
     CDS             complement(1055..2359)
                     /gene="eno"
                     /locus_tag="VUR04_001802"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET5341650.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2523..2969
                     /locus_tag="VUR04_001803"
     CDS             2523..2969
                     /locus_tag="VUR04_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET5341651.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2966..4081)
                     /locus_tag="VUR04_001804"
     CDS             complement(2966..4081)
                     /locus_tag="VUR04_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET5341652.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLQFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4090..4419)
                     /locus_tag="VUR04_001805"
     CDS             complement(4090..4419)
                     /locus_tag="VUR04_001805"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET5341653.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4364..4735)
                     /locus_tag="VUR04_001806"
     CDS             complement(4364..4735)
                     /locus_tag="VUR04_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET5341654.1"
                     /translation="MSQVKGLCVLDVDGTLILEEMIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4794..6227)
                     /gene="glgA"
                     /locus_tag="VUR04_001807"
     CDS             complement(4794..6227)
                     /gene="glgA"
                     /locus_tag="VUR04_001807"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET5341655.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKTKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6224..7363)
                     /gene="glgD"
                     /locus_tag="VUR04_001808"
     CDS             complement(6224..7363)
                     /gene="glgD"
                     /locus_tag="VUR04_001808"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET5341656.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7353..8495)
                     /locus_tag="VUR04_001809"
     CDS             complement(7353..8495)
                     /locus_tag="VUR04_001809"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET5341657.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8485..10413)
                     /gene="glgB"
                     /locus_tag="VUR04_001810"
     CDS             complement(8485..10413)
                     /gene="glgB"
                     /locus_tag="VUR04_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET5341658.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVVVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3261 a         2347 c         1888 g         3205 t
ORIGIN      
        1 atccaactac catccactat gcgctcaaag ctatgggcta cactcgaaaa aaaagaacca
       61 cacctactat gaacaagagc cagaaaaagt agccttattt cttaagaatt ttaatagttt
      121 aaagcaccta gcacctgttt agattgatga aacaggattc gatacttatt tttatcgaga
      181 atatggtcgc tctttaaaag gtcagttaag aagaagatat cagaggattt ctttggttgc
      241 aggtctaacc aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga
      301 cttttttgaa gcatggtttc agaagtttct cttaccaaca ttaaccacac catcggttat
      361 tattatggat aatgcaagat tccatagaat gggtaagcta gaactcttgt gtgaagagtt
      421 tgggcataaa cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac
      481 atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga
      541 ggctcttttg tcttgttctt gtttcaattg actatataaa tcgtctaagc gaaacaaccg
      601 ataagaattg gcacaaaagc ggccgtattt ttgttaccaa tacaggaaaa ccagttcata
      661 gttccatctt gagcaagtct ctccagcgag caaacgaacg ccttaaaaaa ccaattccca
      721 aacatctgtc ccctcacatc ttcagacaca ccactattag catcttatca gaaaataaaa
      781 ttcctttaaa aacaatcacg gacggggttg gtcattctga ctctgaagtc actacttcca
      841 tctacaccca cgccacaaag aacatgaaag atgaagcaat caatgtactg gataaagtta
      901 tgaaaaagat tttttaaaaa gttttgcccc ttttttgtcc tctaaataca aaaatagccc
      961 ttcggataaa atccgagggg ctagaaacgt tgttaaatca acagccgaac ttttgaattt
     1021 catggttcgg gataaaatag ttcactgaac tattttattt tttaaggttg tagaatgatt
     1081 tcaatccacg atattcagct acttcaccaa gttggtcttc gatacgaagc aattggttgt
     1141 atttagcgat gcggtctgta cgtgaaagtg aaccagtctt gatttgtcct gcgttagttg
     1201 caactgcgat atcagcgatt gttgaatctt cagtttcacc tgaacggtgt gatacaacag
     1261 cagtgtaacc agcttcttta gccatttcga tagcttcaaa agtttcagta agagtaccga
     1321 tttggttaac tttgataagg attgagttag cagcaccttc ttggatacca cgtgcaaggt
     1381 agtcagtgtt tgttacgaag aagtcgtcac caacaagttg tactttctta ccaagacgtt
     1441 cagtaagagc tttccaacca tcccagtcgt tttcatccat accatcttca atagtgatga
     1501 ttgggtattt gttaaccaat tcttcaaggt agtcgatttg ttctgcagat gtacgaacag
     1561 cagcaccttc accttcaaat ttagtgtagt cgtaaacttt acgttcttta tcgtagaatt
     1621 ctgatgaagc acagtcaaat ccgataaata cgtctttacc tggtacatat ccagcagctt
     1681 caatcgcagc aaggatagtt tcaacaccat cttcagttcc ttcgaaacga ggagcgaatc
     1741 caccttcgtc acctacggca gtttccaaac cacgtgattt aaggattttc ttaagagcgt
     1801 ggaagatttc agcaccgtaa cgaagggctt ctttaaatgt tggcgcacca actggcaaga
     1861 tcatgaactc ttggaaagcg attggagcgt cagagtgaga accaccgttg atgatgttca
     1921 tcattggagt tggaagaact ttagtgttga atccaccaag gtagctgtaa agtgggattt
     1981 caaggtagtc agcagcagca cgagctacag cgatagacac accgaggatt gcattcgcac
     2041 ccaatttacc tttgttagga gtaccgtcaa gtgcgatcat agcacggtca atagcttgtt
     2101 gatcacgtac atcgtagcca atgatagctt cagcaatgat gttgtttacg ttgtcaacag
     2161 ctttttgtgt accaagacca ccgtaacgag atttgtcacc gtcgcgaagt tcaactgctt
     2221 cgtgttcacc agtagaagct cctgatggaa ccataccacg tccgaaagca cctgattcag
     2281 tgtaaacttc tacttcaagt gttgggttac cgcgtgagtc taggacttcg cgagcgtaaa
     2341 catcagtaat aattgacatt ttttactctc cttatgagtt aaatttttta cacctctata
     2401 ataccttaaa acccctcctt tttcaagaaa aaacgttatc tttgtgcaac ttttccttaa
     2461 ctttataaag taatcgcttt cttttgtctg ttttattcta acttttatga tatactgttt
     2521 tcatgacaga tttatcaaaa caattacttg aaaaagctca tggtgggtta aaaataaatc
     2581 cggatgagca aagacgctat cttggtactt ttgaggaaag agttcttgga tatgtagata
     2641 ttgacacagc aaatagccct cagttagaaa aaggcttttt atttatttta gaaaaccttc
     2701 aggaaaaagc aaagccacta tttgtgaaga tttcaccaac tatcgaattt gataagcaag
     2761 ttttctactt aaaagaagca aaagaaactg atagtcaagc caccatagta tctgaagagc
     2821 atattacttc tccttttggc ctggttattc atagcaatgc accagttcaa gtagaagaaa
     2881 aagaccttcg acttgctttc ccaaaacttt gggaagttaa aaaggaagaa ccagccaaaa
     2941 catccttatg gaagaaatgg tttagctaaa tcttgcacat atttaataag tgcccaatat
     3001 tggcagccgt gcgctccaga tagagactgg catttttcaa actatcttct aaaggttcac
     3061 ttttctccaa aatagaaaaa acagcttgga tattttcaaa ttgtagggga ggtaaatctt
     3121 cagcaagact accgcaaata gcaataacag gaactccaac aggggttctt tttgcaacac
     3181 ctataggcgc tttcccagca aagctttgac tgtcaagtct tccttctcca acaacaacca
     3241 agtcagcatc tgaaactttc ttatcaaagt tgattaagtc caagcaggta tcaattccag
     3301 acacgatact tgcctgagca aaggcacaca aaccaccagc aaggcctcca cctgctcctg
     3361 ctcctttaat ttctaatgtt gcaggtgaga atttttcata aaaatcttgg atcgcctgat
     3421 ctacgactgc aaacatagtc ggatgtagac ctttttgatt gccaaaagtg taagtcgcac
     3481 cttgatgacc acataaggga ctcacgacat ctgctagaat atgaatttga acaccttcag
     3541 gaattttata gcaattttct gttgaaacag aagctaagtt taataaggat tgaccggaag
     3601 caggcaagac atttccatcc ctatcataaa attgataacc taaaccagca gcaatcccca
     3661 gtcctccatc attactggcc gtgccaccaa caccgatata aatatcttta atccctttag
     3721 aaatgagatg gagaatcaac tctccaatac cacaagtttg gatttgaagt ggatttcgtt
     3781 tctctagcgg aatttttcca agaccaacca agtcagctac ttcaaatagt gccagttccc
     3841 ctttttgaaa atagcgcatg gcttcttttt gtccaaaagg gtctgtcact tggatccatt
     3901 tttcttttag gtcaagagaa tgtcggatag catctacagt accttctccc ccatcaccaa
     3961 cagggcagag gagacattct acatctgcta tagattgttg gaagcctctt tttattgctt
     4021 cagctacctg ttgagctgtc aagctttcct taaacgaatc cggtgcaatt acaatcttca
     4081 tattttccct cattctaaac agtcaatcaa aggaagaact tctaaaaaat ccctcttgtc
     4141 aacatgatgt ggtatttctt ttttgagcat ttctttggaa caaaaggcga ttcctaactc
     4201 cgccgacttc aacattaata gattattgac cccatcaccg attgccaccg ttctttcttt
     4261 agaaagtttt agtttctttc tccatttttc cagagtttct tttttgacct ggggacttat
     4321 aatttgtcca actaattttc ctgttaaaag accttctttg acttcaagct ggttggcagt
     4381 gaaataggca ataccaaggg attttgctaa tctctccaac tattggtgta aatccaccag
     4441 acaccagacc aactaggatg ccattctttt ggagaataga gatgaactct gggacattta
     4501 gcgatagatg aattgagttg aagacgttat caaagaccaa aataggaaga ccttccaaca
     4561 aggacactct ttttcttaaa ctgctttcaa agaccaactc tcctcgcatt gctcgacttg
     4621 taatctgcga aatttccgcc tcatgacctg cctctctccc taaaagatca atcatttctt
     4681 ctaggattaa ggttccatct acatccaaaa cacacaagcc ttttacttga gacatcagtt
     4741 ctcctctcta aacagcctaa aaatcgtatg aagtcatcat acgattttat ctattaatta
     4801 actaaactat ggtacaagtc aaggtatgac ttgcaggctg tatcccatga gaagtcactc
     4861 tccatagctt gtttttgtag gtttctccaa atgtctggat ggtttctata caagtccaat
     4921 gctgtttgga aagtccaatt taaccaataa ggagatagat tgtcaaagct aaagccagta
     4981 ccgcttcctt cgattggatt gaaagcgcga actgtatctc gcaagcctcc aacttcatgg
     5041 accaatggca aggttccata acgcatagcc atcatttgag acaagccaca cggttcaaaa
     5101 cgacttggca tgaggaagag gtcacaagca gcgtagattt cctgagcaag tttgacatca
     5161 aaagtgatat ttgttgatag cttgtctggg taaatctgag caaaccatga gaaagctcct
     5221 tcaaaggctg gatcgccagt tcccaaaaga acaatctgaa catcttcttg caagatatgg
     5281 tgaagacttt cgaccaccac atcaaaacct ttttgacgtg tcaaacgaga aacaattccc
     5341 accagtggaa cgtctgctct aacaggcaag ccaactcttt cttgcaattt tgtcttattt
     5401 ttggctttcc cagacaaatc ttcctgattg aaatgatagt ctaaaagagc atccgtctga
     5461 ggattataaa gatcagcatc aatcccattc acgataccag atactttacc agactccatt
     5521 ttaagaatct gatccaaatt acatccaaac tgactagtca taatttcatg agcatagcta
     5581 ggtgaaacgg ttgaaacacg gttcgcatag agaatacctg ccttcatcca gttcagacag
     5641 ttgttccatc gaagggtgcc atcagcgtaa cgttcaaagc caactccaaa caaatcaccc
     5701 aacattcctt ctgaaaattg tccttggaat tctaaattat gaatggttaa aactgtttca
     5761 atgtcctcat aggcttgaat ccaacggtat ttttccttca acaagaaagg aatcatagct
     5821 gtatggtagt catgaacatg gagaagatca ggaataaagt caatcctttc catagcctca
     5881 atggcagcca gttggaaaaa ggcaaagcgt tctccgtcat caaaatcacc gtaaacatga
     5941 ccacggaaga aataatattg attgtcaata aagtagaagg ttacaccatt taatactgtt
     6001 ttcttaattc cacaatactg tctgcgccaa ccaacgctca cctcaaaatg aagcacatct
     6061 tcaatctgat ttccaaattt agcctctacc atatcatagt agggtaaaat cactgcaact
     6121 tcgtgcccag cttttaccag tgattttgga agagcgccaa tgacgtctcc caaaccacct
     6181 gtttttgaaa agggtgcacc ctctgctgct acaaataaaa ttttcatgaa tgaatatcct
     6241 ctgttacttt agcacctttc ttaaccacaa ctggatgttc tgcagttcct cgaatcacaa
     6301 caccaggctc aacttcaacc cctttgtcca agatagcata ttcgacctga gccccttctc
     6361 caataacaac acgagggaag agcaggctat ctttaaccaa gctatcctta tggacatgaa
     6421 tattacgtga tagaacagaa ttagctactt gaccttcaat aatactacca gaggcaaact
     6481 gagaagtgct taccttagat gtattagcat agtaagttgg ctcttcgttt ttgacctttg
     6541 tataaatctt ttggtttggt gagaaaagag aatagaattt ttgtgattca agcatatcga
     6601 tattcgcttg ataataagat ttaacagagt gaatattggc tagatagccc gtgtactcgt
     6661 aggcgaaagc tccctctttt acagccaaat cccgtaaaac atagcgcaat ttctttggat
     6721 gttctttttt agcttcttct tccaagtgtt caatcaacca aggtgtatca acgacaaaga
     6781 tatctgtaga catattgaac gtttcagctg ttgacttgct atcaaagagt ttatgagaaa
     6841 gaacatggtc tgtttcatct acatccaaga ttgcatttac ttctgaaata tctttcttag
     6901 ctagtttttt ataaactaca gtgataggct cttttgttgt actatgtagg tggaaaactt
     6961 ggttcaaatc aatgttaata agaacatcgc agttgagggc aaccgtttgg tttgagccag
     7021 aacgtttcaa ataagtaaga agctgttggt agtattcttt tccaactgta ctactttcta
     7081 cacgggtatt gtaaattcct agatagtaat gactaagaag ggttgataag ccccactcgc
     7141 gtcctgaacg aatatggtca aatactgagc tgatattatc ctgctggaaa ataccaaaga
     7201 cactacgaac acctgcatta gcaaggcttg aaagtgggaa gtcaatcaaa cgatatttcc
     7261 caccaaatgg caaacttgct actggacggt ggtccgtcaa tgtcgacata ttgtgaaaac
     7321 caactgtatt tcctaaaatg gcagaatatt tatcaatctt catctgttgc tacccccact
     7381 acttcattat atcctacaac ttgtacttca tctgttccat caatttcgac accgtcagaa
     7441 ataatcgcac cttcaccaat aatggcacgt ttaatcttag ctccttgacc aatgatagct
     7501 ccactcatga taactgaatc aaggacttcc gctccttcgc gaacttgcgc gcctgttgaa
     7561 aggatagaat gtttaacagt tccatcaacg aaacatccgt ctacaactaa tgagtcttcc
     7621 acatgagcat ttgccccgag gaagtttggt ggtgaaatca agtttcttga gtaaatcttc
     7681 cattgacggt tacgactatc caaggcattt tctggagaaa tatactccat gttcgcttcc
     7741 caaagtgact caatagtacc aacatctttc caataaccac taaattcgta agcataaaca
     7801 ctttcacctg actcaaggta atttggaatg acatttttac caaagtctga catgccaacc
     7861 ttgctctttt cagcagcgac taacatatta cgaaggcgtt gccaatcaaa aatgtagatt
     7921 cccatagaag cttttgtaga tttaggttga gctggttttt cttcaaattc aacaatacga
     7981 ttgttagcat ctgtgttcat gataccaaaa cggcttgctt ctttaagagg gacgtctaaa
     8041 actgctactg tcaagctggc attattatcc ttatgagact ggagcatatc atcatagtcc
     8101 attttgtaga tgtgatcccc agacaaaatc aagacatact caggattgac actgtcgata
     8161 tagtcgatat tttggtaaat agcgtgacta gtcccctcaa accaacgatt tccttcactt
     8221 gcagaataag gttgaagaat agagacacct gaattaatac cgtctagtcc ccagcttgaa
     8281 ccattcccaa tatggttgtt gagagcaagt ggttgatact gtgtaacgac cccaacattg
     8341 tgaatccctg agttggcaca gtttgatagg gcaaagtcaa tgatacggta gcgcccacca
     8401 aattgcacag ctggttttgc gatgctttga gtgagtttac cgagacgagt tccttgccca
     8461 ccagcaagaa tcaaagctaa catttcattt ttcattttct actccttttt ggtttttatt
     8521 tgtgacggtt ttagtagatt tcaagcgacg tttgattttc catacacttg ctcccatagc
     8581 cggtagggta aaggttaagg tctgctcata atctttccat agtccttctt gcgtttgaac
     8641 agtttgatta tgttctttcc aaacgcctcc ccactcttcc aactcagtat tccatacttc
     8701 ttcgtaaatt cctgcaacgg gtagtccgat tgtaaaatct ttccgctcaa caggtaccat
     8761 gttaaagata cagactaaca tttctccctt tttaccctta cgaataaagg aaagaacact
     8821 ctggtctcga ttatccgcat caatgatttc aataccatca tagctggtat cgatttccca
     8881 cagacagcga tgatctttgt aaaactggtt tagctgagaa gtgaaatact tcatcttagc
     8941 attcattggg tcttctaggt tagaccattc caactgttct tcagatttcc attctaggaa
     9001 ttgaccgtat tcgctaccca tgaagagcaa tttcttacca ggatgacaaa tttggtacgt
     9061 atagagattg cgcaagcctg cgaattgatt gtaacgatct ccccacatct tatgcatcat
     9121 actcttcttg ccatgaacca cttcatcgtg cgagaatggc aagagataat tctccttgaa
     9181 aacatacata aagctgaaag tcaccaggtt aaagtcatat ttacgataga tcggatcttc
     9241 ttcgtagaaa cggaggatat cattcatcca gcccatgttc catttgtagt caaatcctag
     9301 accaccaatc tctttcattc ccgtaatctt ggtcgcagac gaactttctt ctgcaatcat
     9361 catcacatct ggatattcta acttaataac ctcattcaag cgttgaagga aataataacc
     9421 ttcatagttg agatttccgc catctttatt aggtgtccat ggagcatcat catagtccaa
     9481 atagagcatg ttgctaacag catccacacg aataccatcc aaatgataga catcaatcca
     9541 atgcttaatg caagaaatta agaaggactg gacttcattt tttccaaggt caaaattaag
     9601 ggcaccccaa ccatggttat gagccttatt atggtcttgg tattcaaaag tcggtgtccc
     9661 atcataatag gctaaggcat catcgttgat ggtaaagtga cctggtaccc agtccacaac
     9721 aaccccaata ttatgggtat gacactcctc gacaaaatct tgaaactcct ctggtcggcc
     9781 ataagcatgc tctaaagcga agtaacccat aagctgatac ccccaactca agcccaaagg
     9841 atgggacatc aagggcataa actcaatatg agtatagttc atttcaacga gataaggaat
     9901 gagttcatcc ttgagctggg caaaactata aggactgcca tcagaatttc ttttccatga
     9961 tccagcgtga acttcataaa tattgacagg acgctcttca aagccccaac gttttcttcg
    10021 tgccagccaa agtccatcct tccatttctt ctcaggaagc tctgttaaga ttgcccctgt
    10081 tcctggacga gcctcatacc tgacagcaaa agggtcaatc ttcatcaatt gatgaccatt
    10141 ttgacgtgtg acatgatatt tgtaaatatg cccttcttga gccatattgg taaagacttc
    10201 ccagacccca aagtcatttc ttaccattgg aatctgattt tcaatccagt tggtaaaatc
    10261 accaaccaag tgaacagcct gagcattagg tgcccaaaca cggaaggtat agccatactc
    10321 tccatttagt tcttccctat gtgctcctag ataatgttgg agataaaaat tttcacccgt
    10381 cataaaggtt tttaatgctt ctctattatc catatactcc ctttctcctg taagcgtttt
    10441 ctatgttttt attatactac ctttttagag aagattcaag taaattacta tacttcttta
    10501 attattttga aaatctacaa caagttcact tactcgttca attgtaaatc agtatttttt
    10561 tcaaaaaaat tgcgaaaacg cctttctttt tctactatag tgaaatgaaa taaaacatgc
    10621 gcaaatcgac taaggaattt aatctaattt ctaacaatgt cttagaaatc aaagtgtact
    10681 attttaactt caatgtatta t
//
LOCUS       DAVDFK010000051        10569 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.51, whole genome shotgun sequence.
ACCESSION   DAVDFK010000051 DAVDFK010000000
VERSION     DAVDFK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.51"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(136..1302)
                     /gene="recA"
                     /locus_tag="VUR04_001811"
     CDS             complement(136..1302)
                     /gene="recA"
                     /locus_tag="VUR04_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET5341659.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1357..2613)
                     /locus_tag="VUR04_001812"
     CDS             complement(1357..2613)
                     /locus_tag="VUR04_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET5341660.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2697..3713)
                     /locus_tag="VUR04_001813"
     CDS             complement(2697..3713)
                     /locus_tag="VUR04_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET5341661.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3721..4239)
                     /locus_tag="VUR04_001814"
     CDS             complement(3721..4239)
                     /locus_tag="VUR04_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341662.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4229..4672)
                     /gene="tsaE"
                     /locus_tag="VUR04_001815"
     CDS             complement(4229..4672)
                     /gene="tsaE"
                     /locus_tag="VUR04_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET5341663.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4758..5378)
                     /locus_tag="VUR04_001816"
     CDS             complement(4758..5378)
                     /locus_tag="VUR04_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341664.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5760..6623)
                     /locus_tag="VUR04_001817"
     CDS             complement(5760..6623)
                     /locus_tag="VUR04_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341665.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAKGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKAIIDFYQYELQFEAISHLENILSKVASTTLIYLKVLNTLSNFY
                     SLVGREEDYEANYSHLIELYQTKNLDHQEVLFGYIRVRYNYVHYLVSKEKYNEAMQEA
                     LETIELCKERQTSYQLAPLLVLVGNCGTQFLGKEQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDAV"
     gene            7425..9440
                     /locus_tag="VUR04_001818"
     CDS             7425..9440
                     /locus_tag="VUR04_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5341666.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGEGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            9442..10074
                     /locus_tag="VUR04_001819"
     CDS             9442..10074
                     /locus_tag="VUR04_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341667.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVTLAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT         3208 a         2143 c         1875 g         3343 t
ORIGIN      
        1 tgctaaaaca tttctagaaa ttaatttgac tttcctaata gagttgttca tatcttattt
       61 caagctacta tatataatct aaaaacttga atcaaaaatc gaaaaagtag cggatttctc
      121 cactgcttta acagcttatt cttcaatttc gatttcaagt tcatcgccta agtcaagcgg
      181 aacttcttca ttcactgctt cttctttctt tggctcatct tttttgtttt cagtatcttg
      241 ttctgaaact tcttctccat caatcaagcc aaatttagaa cggacttgct tatcaatttc
      301 atcaaagatt tctgggtgct ctgccaagta tttcttagca ttctcagaac cttgcccaat
      361 tttttcatct ttgtaagaat accaagcccc tgcttttttg ataatatcca aatcgcttgc
      421 aatcttcaaa agctcaccag tcttagaaat tccttctccg tacataattt caactacggc
      481 ttccttaaac ggtggagcta ccttattttt tacaacctta atcttagttt ctttaccgac
      541 attggtttct ttttggtcac cagttccctt aatttgtgta ttaccacgaa catccaagcg
      601 gactgaagca tagaatttca aagcacgtcc gcccggtgtt gtttctggat ttccaaacat
      661 cactccaact ttttcacgca attggttgat aaaaatggca attgttttgg ttttattgat
      721 agaggcgcca agtttacgca tggcctggct catcatacga gcctgcaaac caacatggct
      781 atctccgata tctccatcaa tttccgcacg aggaacaagg gcagcaactg agtcgactac
      841 gacaagatca actgcacctg agtcaatcaa ttttcccgca atctcaagac cttgctctcc
      901 tgagtctggt tgagacaaga gcaattcgtc aatattgaca ccaagggccg cagcataagc
      961 tggatcaagg gcatgttccg catcgataaa ggcagcaatc ccaccttctt tttgcgcttg
     1021 tgcaactgca tgaagggcaa ccgttgtctt accagatgac tctgggccat agatttcgat
     1081 gatacgtccc ttaggataac cacctgagcc aagggcaatg tcaagagcta aagaacctga
     1141 gctcatcact tgcacctttt gctccgcacg ttcacccaaa cgcatgattg atcctttacc
     1201 aaagtctttc tcaatcaatt taagagcgtc attcaaggcc ttttcacgtt ctgccccaaa
     1261 tttttttgaa atttcttcta atttttttgg ttttttcgcc attctattct cctacattct
     1321 aatgatcctc agacctatct actattatat caaaagttag tcacttaata aagccttgcg
     1381 aactaggtta aaggcatgca taaccgcaat gtgacgtaca tctgctcggc ttctgcctcc
     1441 aatattaacc ttgataacct cagttccttg atcttgcgcc aagcctatga agactgtccc
     1501 aactgggtgt ccttctaggc tatctggtcc tgccactcca gtcaaactaa ttccaaaatc
     1561 agactgggtc ttgcttcgtg cctgctcagc catcttctga gctgtaaatt cagacaccac
     1621 accatgttct tccaaattct tggcaggaat atccaacatc cttgattttt cctccaagct
     1681 ataggtcaca aaaccaccct taaatatact tgaaactcca gaaaaattcg ccacggtagc
     1741 ttggaaaaga cctgccgtca aactctctgc agccgcgatg gttttccctt gccttttcag
     1801 ttcttctacc acaatgctgg ctaaactagt ttcttcccca taaccatagc aaaagtctcg
     1861 taaagaaatt ccttcgaaag tctggcagtc caagatttga ttttccaaga tatccagcgc
     1921 ttgattcgcc tcttcttgac tgctagcctt tgttgacaga cgtagagtga cttctcctgt
     1981 cttggcataa ggggccaagg taggatcgat ctgattatca attaaatcag ccaaaatcgt
     2041 aaccaactgg ctctcgccaa tcccaaagaa acgaagaact cgggaataca gcttgctccc
     2101 tgtcatcaac ttgggtagaa gttggtttaa gaccatgggt ttcaattcac ttggcggacc
     2161 tggaaggacg acataggtca ctccgtctac ttctaatttt cctccaacag ccagtcctgt
     2221 ttcgtttggc agtggaatcg ctccttctac aatttgagct tgtctttcgt tattcggtgt
     2281 tcgggcatag tctggtcgca gggcaaaaaa gatatccaac ttctcctgag cctgaggatc
     2341 aaagactaat gctttcccta aaaatttagc tagggtttgt ttggttaggt cgtcctcagt
     2401 tggccccaaa ccgcctgtca aaatcaccag actgctacgt tgactggcaa tctcaagcaa
     2461 agacaagaga cgaacttcat tgtctcctac agccgtctga aaatatacat ctaccccaat
     2521 ctcagctagt ttttccgaca aaaactgggc attggtgttg acaatctgtc ctgtcaaaat
     2581 ctctgttcca acagcaatga tttctgcttt catgtttcct cctacctatc tattcgtatt
     2641 tttttgaaaa aatcgcagga attttcctac gattgatttt ttatttgtat caaaagttaa
     2701 ttatcttcat caccaacagg tgctctgcca aataaatctt caaataaaac cgcattggtt
     2761 tcaagctgag taacttcttc ttgtcccaaa gaacgtcgga gtatattttg catttccaac
     2821 atatgtgctc tcgaaacaat ctggtaagaa acaccttgaa gtatctctcc ttcaccctgc
     2881 aactgctgag tttcaatggt tttaaatgaa tctttatagc ctagcaagtt agggatactt
     2941 tttgcagaca aatcaatatt ggtctgcata ttgtcactca aagcttttag aatctcttga
     3001 taatgaccaa tgctatttaa actgagagct ttttccatga ctttttgaat aacttcacgt
     3061 tgacgttttt gacgaccata atccccctca ggatcttggt aacgcattcg tgcatagact
     3121 agggcttctt ctcccccaat atgttgctcc ccaacaccga tagaaatagt attaaattct
     3181 tcttggtcac tgatagaaat tgggaaacct aggatattat tgactgtaat acctcctact
     3241 gcatccacta gtttttgcaa tcctctcata ttgaccatca catagcgatc aatatggata
     3301 ttcatcattt tttgaatggt ttctatagca agctctgctc caccatctgc atatgctgag
     3361 ttcagtttcg cttcatgagc ctgaccattc cctgattcaa tgcgcgtcag aatatcccgc
     3421 tctaaactca tcattgttgt ttttttcgtt ttaggattca ctgtcatcaa gatcatgcta
     3481 tcacttctac cgacccaagt ttcagttcgt tcaacatttc cggtgtccac tcccattaac
     3541 agaatggtta gaggttcagt cgcttcaata accttggttt cttcgccgat ttttttatag
     3601 gttttagcta aggtttctgt cccttgttga taaatagtat aagcaaaaac acctactcct
     3661 actacagtta cagaaagtaa agctagcacc attccaataa tttttttaac catatttcta
     3721 ctaacctatc agtttaccca tcaagtaaac atcgataaat ttcccttctt ctatatatgc
     3781 cccacgctct tggctacctt caatgacaaa gccatgcttt tgataaagat ggactgctgc
     3841 ttgattacga gtttggacag tcagttggag acgacgcaga atgccacttg cttgtgccca
     3901 ctctatcgct tcttctagca acaaacttcc caagccatta ttccaatatc tttttccaat
     3961 cacaatgaag agatctccaa tatgacggac tctcttacgc tggtcagctg taatatttac
     4021 aataccagca attttgccat ttaagaatgc aagtaaggtt atctgattgt ccgaactagc
     4081 ttgcttgttg aggaatattt ccatctcctc actagtcaag agaataccat ctccgtctag
     4141 gctggtaaag tctgtctcca aactcacacg atttaaaaag gccactaatt cagctgcatc
     4201 tttgggctct gcttccctaa tgagcaattc atactccata ttgaagctcc tctaacaatt
     4261 tctcagcacg caaacccttt gcctgaaaat ttaaacggcg tccatctgct tcttttagaa
     4321 tttccaattc taaataagca tctggcaagg catctcctaa gagatttccc cactcaataa
     4381 cagtcacgcc gccaccaaag ataaactcat ccaagtcgat agaatcagca tctccttcaa
     4441 tacgataaac atctaggtga taaagtggaa gtcgaccttc atactctctc acgatagtat
     4501 aggtgggact tttaatcatt tgagaaatct gtaatccttt tgcaagtcct ttagtaaagg
     4561 tcgttttacc tgcacccagt tctccagtta agattaaaac atcattcttt gctaatagat
     4621 ggcccaaacg ctcccctaag gcttgcaact cttcttcatt ttttgtgtac atactcttat
     4681 tataccaaaa acttttcttt tgtgtctatt ttcctactaa acttatcatc ataacatcca
     4741 taaaaaacag gctttctcta aaagaaaatg agcgtaacaa tgaccaatac aagatctcgg
     4801 aaaatatgac cataaaagga aacttccttc ttaaccgaat ttgggacaag ataggctgca
     4861 aaaaacaagc ccagtccaat ataaatcaga agtgagacaa tggtcattgg atttcttaag
     4921 aaaagaagtg ttgctaaaat agtcaccaac actgtctttt ttctgtctag catagcaaga
     4981 aaatcgcgca cgtatttttt caagggtaaa aaaatcagca aatctagccc aaataggaaa
     5041 aagaaggatg gcaataaaaa gtcaactaat tcttgctgca gcgtattttt gatgaacaag
     5101 ttatctgaca aaacaagaac agctcctaac aaattaatta agagtaacat actgtaaaaa
     5161 agcttcaccg acttcttact ggctaggaca ctatggactt cttgcttacg ggtataaaga
     5221 taatttactc cagcacagat tcctgaaacg aaaaccatgc ttccgatgaa aaaagctgta
     5281 ctttgtttaa aggacaagat gcattccttc cataggaaac agctactcaa actgatttga
     5341 attaaagcta acaaaaataa gattctcatt gatttcatct tctctctccc ttcctaccaa
     5401 tcattatact aggagaaaag agagaactgt ttctaatctt ctcaaatgtc tctttaagac
     5461 gctaaacaaa cactagagac taatactcaa tgaaaatcaa agagcaaact aggtagctag
     5521 ccacaggttg ctcaaaacac tgttttgaga ttgcagatag agctgacgtg gtttgaagag
     5581 attttcgaag aatataaatt tgaaatcatg aaaatccgtc aaacgggtgg ttgttttgtc
     5641 tcgcacctca cggagcgaga cgactcagag tcacataatt ataaggctga tagtattaat
     5701 ctaactatca gccttacagg ctatttaatg tttaagtaac actccaatat caagataaac
     5761 taaacagcat ctagttcctt caaataattt tctatcttca tcagcattaa aggattgtta
     5821 taaatcttgc atagctctct tgcttctata taataatttt tgacttgttc tttgccaagg
     5881 aattgtgttc cacaatttcc aacgagaacg agcaggggag ctagttggta acttgtttgc
     5941 ctctctttac agagttcgat agtctcaagg gcttcttgca tggcttcgtt gtatttttct
     6001 tttgagacta aatagtgaac atagttgtaa cgaactctga tataaccaaa caaaacctct
     6061 tgatggtcca aattttttgt ctgatacaac tctattaaat gagagtagtt tgcttcataa
     6121 tcttcttcac gaccaacaag ggaatagaag ttagacagtg tgtttaatac ttttaagtaa
     6181 atcagagtag ttgaggctac ttttgataat atattttcca agtgagagat agcctcaaat
     6241 tgaagttcat attgatagaa gtcaataata gctttaatcc attcaaggta agttcgatct
     6301 tctagtgtta gaaaggtgct tcgctcaacc tctattttat aaagatattc taaatcgtca
     6361 taatttctat catccaatag acgagcagat aattgcttga aattagagag gttagattta
     6421 atttcaattt gttcattaaa aaaataatct aatggcactt cgagtcgttg tgagagtttg
     6481 aacaaaaggt ctgcggaggg aatgaaatgc cctctctcaa ttttactaat ctggctctgt
     6541 tcacaaattc cttttgcaag agtttgttgg gagagtctca actcttttct tttcaatctg
     6601 aatttttctg cgagtgtatt cattaaagat aataatcctt cctatttgct taatttcatt
     6661 ataaaatttt tagttcaaaa tagcaagtta aaggaataaa taattctcta tggtaataat
     6721 aaaaaagttc aaaatacaat aaaaatactt gactgaataa aatatatctg ttaaaataag
     6781 gataatgaaa aagaaaaggg tttcacgaat gaagaaaaat cgtggaattc aaaaattagc
     6841 tatattagca ttactaggtg tttttacatt tagtaacaca attccttacc aacagttatt
     6901 cagaagaata aacaattgga gattcgagtc caatcacaaa agaagtccaa tggtcttgat
     6961 gttgggaagg ctgattgatt tcgtattact ttaaaattca actatttaga gaaaggtatt
     7021 ctgatgagag cttgtaacaa taccagatag atataagaat ggagatgttt gataaaatgc
     7081 tttcatagct aaccaactgt tgaaaattat gagttacaaa atctaaagta tttaagattg
     7141 gtttataaaa ttagatctct gtctgtagaa aggaacgtgc agttagaaag gaggaaaaaa
     7201 taggatacta taattcagac tgagatttct aattaaaata tatagttgca tttcgctcat
     7261 tttcataata tttcattcag aggagtaata atatgttaaa attttttgat gcgggatggt
     7321 aaagaataat tgaagaagat tcttttatca atagtttagt aagcttgtta atttatagag
     7381 ggcaggggta tttctgccct ctgttttaga ataaggaatg cactatgaaa aaattattta
     7441 tactcatatc caacctgctt gctagtttgt tctttgtttg ggtatttacc atttggactg
     7501 atacatatgt ctcctattat taccccaacg ttgttgtaca tgattcttcc cctgaaacaa
     7561 cttttcagca tgttgctaca cgcttggaaa aactagcaga agaaacagat agctttattg
     7621 cgattcaaca ccaagatcct aactcagaag gtactacagt tttttcttat acgacctttg
     7681 gggacggaaa gttgcctgat gggcttcagg aaaaaaaact agaagatgct caaagtagta
     7741 gtgttgaaac aaactatttt gtattcgatg gacacctaga tattcacttg ctaagggagg
     7801 agctaagtca acttggcttg actaacatga acctgacaat tccatctaaa ctatctacgt
     7861 taatggctat ctttagtaac ggatttcagt taatcagtct attgattttc atcttaacct
     7921 ttgtagcact gactttaatt agtcaaatta gccaattacg gtcatcgggc attcgcctca
     7981 tttcaggaga gaaacggtgg tccattttcc ttagaccagt tggtgaggat ttgaaagcga
     8041 tagctgttgg tttcagttta gctggcgtgc tcgccattct tatgcaaaaa attctgtcgc
     8101 ttccaacgca atccctaatg accataggag aaggcttgct cagttataat ctcatcttgt
     8161 tgtcgatctc cctgtttttc gctcaactct tcgcagttgg gataaaaaag atacacctga
     8221 tgcagattat aaaagggcaa gtgcctgtca gaggaatcat tagtttgatt ttaatcggtc
     8281 aactattagc gattattatt gtaacgctgg gaatagggag tagcttaaag tattcccaag
     8341 cctggcaaca gcatcggatt ggacaagagg tttggagtca ggaaaggcaa ctgattaccc
     8401 tatcaatcag ccgtgaagga acgagtcctg gttttgatga acaagctcaa aggaaactca
     8461 gaacttggta tcaattgatg gatctggctg tttcagaaca aaaggctttc ttatctagac
     8521 accagttaat tgaccgtact ttgcaaaatg gcatggcttc ctccaaaaac ttgataacct
     8581 ctacagaatg gcacgattac aacccgaatg gcaatgtcct tatcgtcaca ccgcaatact
     8641 tggagcgtca aaacattcct gtagatacaa ctattgagca aaagatgaat caccttgatg
     8701 taggggagtt tgtcttattg ctgcctgaac acctccgttc agaggaagaa cattataaat
     8761 ctgtttttga agacgactta accagtcgca tgtctagtca agatgaacga cagcaaatga
     8821 ctgctacggt aggttattta gaatcaggtc aggatcgttt tgtgtataat acgaccccta
     8881 tttcttacca gcagtttttg aaagatccaa tcatcattgt tataacaccc caatcaactg
     8941 gtccacagtc cattttgttt tggatagacg cagtacagaa ctacgttctc tttaatcaat
     9001 tgtctgatgc ccaggagctt atccagagac aaggcattga aaattgggtc tcagaaatgc
     9061 aaacaggtta ccacaactac atcacattat tggataatat ccagagggaa cgttgggtaa
     9121 tgctagcagg agctgtgctt gggattgcaa cttcaatctt gttgtttaac actatgaata
     9181 ggctctactt tgaagaattt agacgtgcca tttttatcaa acgcattgca ggtctcaggt
     9241 tcttagaaat ccatcgcact tatctctttg ctcaactggg tgtgttttta ctgggatttg
     9301 ttgcgagtgt atttcttcag gtagagatag gagttgcttt cttagtcttg ttactcttta
     9361 ctggtctatc tcttttacag ttacatgtcc aaatgcagaa agaaaacaag atgtccattc
     9421 ttgttttgaa gggaggttaa tatgattgaa cttaaacagg tgagtaaatc ttttggagaa
     9481 cgagagttat tttcgaatct ttcaatgaca tttgaggctg gaaaagtcta tgccttaatt
     9541 ggttcaagtg gtagcggaaa aacaaccttg atgaacatga ttgggaaatt agaaccttat
     9601 gatgggacga ttttttaccg aggtaaagac ttggccaatt ataaatcgag tgattttttc
     9661 cgtcacgaat tgggctacct cttccagaac tttggcttaa ttgaaaacca aagtattgaa
     9721 gaaaacctta agctaggtct cattggtcaa aagttgagtc ggtcggaaca gcggttgagg
     9781 cagaagcagg ctttagaaca ggtcggcctg gcttatcttg acctagataa gcgcatcttt
     9841 gagttatcgg gcggagaatc gcaacgggtt accttggcaa aaattatctt aaagaatcca
     9901 ccctttattc tggcagatga gccaacagct tcaatagacc cagcaacctc tcagttgatt
     9961 atggagattt tgctatctct tcgagatgat aataggctaa tcattatcgc aacacataat
    10021 ccggcaattt gggagatggc tgatgaagtg ttcacgatgg atcatctgaa ataaaaatcc
    10081 ttgtttttaa ttgcacgatg agttactgaa atattatcat gaatcaagaa ttggagttaa
    10141 tttagaattg tactttatta atattgaggt aactttttct tgataaagga agaaataatg
    10201 gagaggaagt tagaatgaaa aaattcgaca attatattat tgagaagcct tgcgattcta
    10261 attcagataa actgcaaaaa atcttaataa ttgaaagttt ggtagatgat attttgcaat
    10321 tttctctcag aatcaataat agtgtaggag agattttcct cctacaaccg ttttaaaaga
    10381 aaactatctt tattccatgt tattttgagg aagatattgt gaaagtcaaa gatgatgata
    10441 aagttgagtg gaatttgtta gaatttcaaa aatttagagc atttttggct tagtaatctg
    10501 tgttgaaggc tcaaaaccta tggtaaaaaa gtagctttga aaacgtattg cctccaaaga
    10561 tttagttaa
//
LOCUS       DAVDFK010000052        10318 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.52, whole genome shotgun sequence.
ACCESSION   DAVDFK010000052 DAVDFK010000000
VERSION     DAVDFK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.52"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            110..279
                     /locus_tag="VUR04_001820"
                     /pseudo
     CDS             110..279
                     /locus_tag="VUR04_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            479..3754
                     /gene="rexB"
                     /locus_tag="VUR04_001821"
     CDS             479..3754
                     /gene="rexB"
                     /locus_tag="VUR04_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET5341668.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELNPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3751..7401
                     /gene="addA"
                     /locus_tag="VUR04_001822"
     CDS             3751..7401
                     /gene="addA"
                     /locus_tag="VUR04_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET5341669.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SKSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLNPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFISHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLIILKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLNQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFSYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPGLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7571..8749
                     /locus_tag="VUR04_001823"
     CDS             7571..8749
                     /locus_tag="VUR04_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341670.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKIENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQNQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8958..>10318
                     /locus_tag="VUR04_001824"
     CDS             8958..>10318
                     /locus_tag="VUR04_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5341671.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NEMQALVAGASLATLGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEENITSESEVSNQKSSIVTPTKQQKVDY
                     SVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLSEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPTIQPELPEAVVSDKGVPEVQPALPKAVVTDKG
                     EPAV"
BASE COUNT         3291 a         2084 c         2155 g         2788 t
ORIGIN      
        1 cctgttcgct cacaataaga gagaactttt ttacgaaaat ctattgaata tgccataaaa
       61 agattatacc acattgtgta ctatttttgg ttcattttac tatagttcaa tcattctatc
      121 aagaatattg aatatataaa ggcacgtaat attaaaactt cttctgatat cgaattagag
      181 tccgatgttg atggcgataa atcagacaat ctaccagtcg acattaagat actgggacaa
      241 cacattgaag tgtattccgt acctaagaaa caatcataaa actcaaagcc ttgttaccga
      301 ggctttttta ttatgtgatt ttcagtagcc agacttattc tatctaatac aagtaaagct
      361 aagtatttaa gatttagcag atgatgaaaa aaagaaagga tggcctaaat attttaacag
      421 atttacgagg ctaatcatgg tataatatag ggtaatgaaa aattccaacg aggctgagat
      481 gaaattactt tatactgata ttcggacttc tttgacagaa attctaacaa gagaggcaga
      541 agagctagtt gcagctggca agcgggtctt ctacattgcc cccaactctc tttcttttga
      601 aaaggaacgc gccgtgctgg aatgcttgtc ccagcaggct tctttttcga ttaccgtcac
      661 gcgctttgct caaatggctc gttatctggt cttgaatgat ttaccagcta aaactactct
      721 tgatgatatc ggtcttgggt tggcctttta caaatgcctt gccgaactca atcccaagga
      781 cttgcgtgtt tatggcgcta ttaagcagga tcctcaattg atccagcagt taattgagct
      841 ttaccatgag atgaccaaat cccagatgag ttttttggac ttggagaatt taacagatga
      901 ggataaaagg gcggatttac tcttgatttt tgagaaagta acagcctatc ttaatcaagg
      961 tcagttagcc cagggaagtc agttgtccca tttgattgag gctattgaga atgacaaggt
     1021 aagtagtgat tttaatcaaa tcgccttggt cattgacggc tttactcgtt tttctgctga
     1081 ggaagagcgg gttgtggact tacttcacgg caaaggtgtt gagattgtta tcggggctta
     1141 tgctagtaag aaagcctata ccagtccttt tagcgagggc aatctctacc aagccagcgt
     1201 aaaatttctc catcatctgg cttctaaata ccaaacgcct gctcaggact gttctcaaac
     1261 tcatgagaag atggatagtt ttgacaaggc ctctcgtttg ttggagtctt cttatgactt
     1321 ttcagaactc gctttggatg tcgatgagaa agaccgtgaa aatttacaaa tctggtcttg
     1381 tttgacgcaa aaggaggagt tggagctagt agcccgtagt attcgtcaga aattacatga
     1441 gaactcagac ctgagctaca agcattttcg tattctcttg ggggatgtag cttcttacca
     1501 gttatctctc aaaaccattt ttgaccagta tcagattcct ttttatcttg gtagaagcga
     1561 agccatggct catcatccct tgactcagtt tgtcgagtct attttagctt taaaacgtta
     1621 ccgttttcgt caggaggatt tgattaatct tcttagaact gacttgtata ctgacctcag
     1681 tcagtctgat attgatgctt ttgagcaata tatccgctat cttggtatca atggcttgcc
     1741 agcctttcag caaaccttca ccaaatccca ccatggaaaa tttaatcttg agcgtttgaa
     1801 tgtcctccgc ctgagaattt tagcacctct tgaaaccctc tttgccagcc gaaaacaaaa
     1861 ggctgaaaac ctcctacaaa aatggagtgt ctttctaaaa gaaggagctg tgaccaagca
     1921 gttacaagat ttgacaacca ctttggaagc tgtagaacaa gaaagacaag ccgaagtttg
     1981 gaaggctttc tgccatgttt tagaacaatt tgcgactgtt tttgctggtt cacaggttag
     2041 tctggaagac ttcctagcct tgctccattc tggaatgagt ttgtcccaat accgtaccat
     2101 tccagcaaca gtggacactg ttctggtgca gagttacgat ttgattgcac cattgactgc
     2161 tgactttgtc tatgctattg gactaactca ggacaattta ccaaaaattt ctcaaaacac
     2221 cagtcttctg acagatgaag aaaggcaaaa cctaaaccaa acgaccgaag aaggcgttca
     2281 attactgatt gccagcagtg aaaatctcaa gaaaaatcgc tacactatgc tttccttggt
     2341 caattctgct cgtaagcagt tgttcttgtc ggctccaagc ctttttaacg aaagtgaaag
     2401 taaggaatct gcctatcttc aagagttgat ccattttgga tttaggcgga gagagaagag
     2461 gatgaatcac aaaggactgt ctaaggagga tatggggtcc tatcacagtc ttttgtctag
     2521 tctggttgcc tatcaccagc agggtgagat gagcgatact gagcaagatt tgacttttgt
     2581 caaggttctg tcgcgtgtca taggtaaaaa actagatcag caaggtctgg aaaatccagc
     2641 catcccaatc agtccaagta gcaagacctt agccaaggac accttgcaag ctctctatcc
     2701 tgccaaacag gagttttacc tgtctacgtc gggtttgaca gagttttatc gcaatgaata
     2761 cagttatttc ctacgctacg ttttaggctt gcaggaggaa ttacgtttgc gtcctgatgc
     2821 ccgtagtcac gggaatttct tgcatcgtat ctttgaacgc gccttgcagt tgcctaatga
     2881 agattccttt gaccaacgtc tagaacaagc tattcaagaa accagtcaag aacgcgaatt
     2941 tgaagctatt tatcaagaaa gtttggaagc ccagtttacc aaggaagttt tgcttgatgt
     3001 tgcacggaca actggacata ttctccgaca caatccagcc atcgaaacca tcaaagaaga
     3061 agcaaatttt ggtggaaaag accaagcctt tattcaatta gacaatggac gcagtgtctt
     3121 tgtacgaggc aaggtggacc ggattgaccg tttgaaagct aatggagcga taggagtagt
     3181 agactacaaa tccagtctga ctcagttcca gtttcctcat ttctttaatg ggctcaattc
     3241 tcagttacca acctatcttg ctgccctaaa aagagaaggg gagcagaact ttttcggcgc
     3301 catgtacttg gaaatggctg aacctgtcca atctctgatg gcggtaaaaa gtctggcagg
     3361 agcagtggta gaagccagca aatctatgaa ataccaaggg ctcttcttgg aaaaagaaag
     3421 cagttattta ggcgaatttt ataacaaaaa caaggctaat caactgacag atgaggaatt
     3481 tcagctccta ctggactaca atgcctatct ttacaagaaa gctgctgaga agattttagc
     3541 aggccggttc gccatcaatc cttatactga aaatggcaga agcattgccc catacgtcca
     3601 gcaacatcag gctattacag gctttgaagc caattaccat ctgggccaag cccgtttcct
     3661 agaaaagttg gacctagctg atggcaagcg tctggtcgga gaaaaactca agcaagcttg
     3721 gcttgaaaaa ataagagagg agttgaatcg atgaagctta ttcccttttt aagtgaggag
     3781 gagattcaaa aactgcaaga agcagaagca aattcgagca aggaacaaaa gaaaactgcc
     3841 gagcaaatcg aagctatcta cacttctggt cagaatatcc tggtctcagc atcggctggt
     3901 tctggaaaga cctttgtcat ggcagagcgc attctggacc aattggcgcg tggtgtcgaa
     3961 atttctcaac tctttatctc aacctttacc gtcaaggctg caactgaact taaagaacgt
     4021 ttagagaaaa aaatcagcaa gaaaatccaa gaaacagatg atgtcgagct caaacaacac
     4081 ttgggtcgcc agttggcaga cctacccaac gctgccatcg gaaccatgga ctctttcaca
     4141 caaaaattcc ttggcaaaca tggttatctg cttgatattg cacctaattt ccgtatttta
     4201 caaaatcaaa gcgagcaact tcttctcgaa aacgaagtct ttcatgaggt ctttgaagcg
     4261 cattaccaag gtaaacagaa agagaccttt agtcatttgc tgaaaaattt tgctgggcgt
     4321 ggcaaggacg aacggggtct gcgccagcag gtctataaaa tctatgactt cctccaatcc
     4381 accagtaatc ctcaaaagtg gctgagtaaa tctttcctca aaggttttga gaaagctgat
     4441 tttaccagtg aaaaagaaaa actgactgag caaatcaaac aagccctttg ggatttggaa
     4501 agctttttcc gttaccatct ggataacgat gccaaggagt ttgcaaaggc tgcctattta
     4561 gaaaatgttc agttaattct ggatgaaatt ggctccctaa atcaggagtc cgatagtcag
     4621 gcttatcagg cagtgcttgc gcgtgttgtc gccatctcta aggagaaaaa cggtcgagct
     4681 ctgactaatg ccagccgtaa ggctgatttg aatcccctgg ctgatgccta caacgaagag
     4741 agaaagaccc agtttgctaa actaggacaa ttatcagacc agataaccat tctcgactat
     4801 caagaacgtt atcatcaaga cacatgggaa ctagctaaaa ccttccaaac ctttataagt
     4861 cattttgtgg aggcttatcg tcagagaaaa cgacaggaaa atgcctttga attcgctgat
     4921 atcagccatt acaccattga gattttagag aatttcccac aagttcgtga gtcttatcag
     4981 gagcgcttcc atgaagtcat ggtcgatgag tatcaggata ccaaccatat tcaagaacgg
     5041 atgctggaat tgttgtctaa tggccacaat cgctttatgg tgggagatat caagcaatcc
     5101 atctatcgtt tccgtcaggc agacccgcag attttcaatg agaaattcca acgctatgcg
     5161 caaaatcccc aagaaggcaa gctcattatc ctcaaggaaa atttccgtag tagttcagaa
     5221 gtgctgtcag caaccaatga tgtctttgaa cgtctcatgg accaagaggt cggcgaaatc
     5281 aactatgata acaagcacca gcttgttttt gccaatacca aactgactcc caatccagac
     5341 aacaaggcag aatttctcct ctacgacaag gacgatacag gtgaggaaga agagagtcaa
     5401 acagaaacga aactaacagg cgaaatgcgc ttagttatca aggagattct gaaacttcat
     5461 caagaaaaag gtgttgcctt taaggaaatt gcccttctga cctccagccg cagtcgtaat
     5521 gaccagattc tcctcgccct gtctgagtac gggattcctg tcaaaactga cggagagcaa
     5581 aacaattatc tccaatccct agaagtgcaa gtcatgctag acactcttcg tgtcattcac
     5641 aatcccctgc aagactacgc cttggttgcc cttatgaagt ctccaatgtt tggttttgat
     5701 gaggatgagc tagcacgttt gtcccttcag aaagcagagg ataaagtcca cgaaaatctc
     5761 tatgagaaac tggtcaatgc acaaaaaatg gcaagtagtc aaaaaggctt gattcacaca
     5821 gctctagctg aaaaactaaa tcaattcatg gatatcctag cttcttggcg cttgtatgcc
     5881 aaaacccact ctctctatga cttgatttgg aagatttaca acgaccgttt ttattatgac
     5941 tatgttgggg ctttgccgaa tggtcctgct aggcaggcca atctctatgc cctagcactg
     6001 cgtgctgatc aatttgaaaa gagcaatttc aaaggtttgt cgcgttttat tcgtatgatt
     6061 gaccaagtct tagaagccca gcacgatttg gcaagcgtgg ccgtcgcacc gccaaaagat
     6121 gcagtagagc tcatgaccat ccacaagagt aaagggctgg agttttctta cgtctttatc
     6181 ctcaatatgg atcaagattt caacaagcaa gactctatgt cagaagtcat tctcagtcgt
     6241 cagaatggtc ttggtgtcaa atatattgcc aagatggaga caggggcagt agaagaccac
     6301 tatcctaaaa ccatcaaact ctccattcct ggtctgacct ataggcagaa cgaagaggaa
     6361 ttacagctag caagctattc tgagcagatg cgtttgctgt atgttgctat gacgcgggct
     6421 gagaaaaagc tctatcttgt cggcaagggt tctcgtgaaa agctggaatc caaggaatac
     6481 ccagcagcca aaaatgggaa actaaatagc aatactagac tgcaagcacg gaatttccaa
     6541 gattggcttt gggctatcag taaagtgttt actaaggaca agctcaactt tagttatcgt
     6601 tttattggcg aagatcagtt gaccagagaa gctatcggag agttggaaac caagagtcct
     6661 ctccaagata gctcccaagc agacaatcgt cagtcagata ccatcaaaga agctctggaa
     6721 atgctgaagg aggtggaagt ttataatact cttcaccgcg cagctattga acttcctagt
     6781 gttcaaactc caagtcaaat caagaaattc tacgaaccag ttatggatat ggaaggtgtc
     6841 gagattgctg gtcaaggtca gtcagtaggc aagaaaatca gctttgattt gccagatttt
     6901 tcaaccaaag aaaaggtaac tggagctgag attggtagtg ctactcacga actcatgcag
     6961 agaattgacc tcagccagca actaaccctt gctagcctaa cagaaacact caaacaagtt
     7021 caaactagcc aagctgtcag agacaagatc aatcttgata aaattcttgc tttctttgac
     7081 acagcactcg gtcaggaaat tcttgctaat accgaccatc tctatcgcga gcaacctttc
     7141 tccatgctca aacgagacca aaagagtcag gaagactttg ttgtccgtgg tatccttgat
     7201 ggctatctgc tttacgaaaa caaaattgtt ctgttcgact acaagacaga ccgctatgat
     7261 gaaccaagtc aactcgtaga ccgctatcgt ggtcagttag ctctatacga agaggcttta
     7321 tcacgagcct attcgattga aaatattgaa aaatacttga ttttactcgg taaagacgag
     7381 gttcaagttg taaaagtata acttatactc ttcgaaaatc tcttcaaacc acgtcagctt
     7441 cgccttgctg tatatatggt tactgacttc gtcagttcta tccacaacct caaaacagtg
     7501 ttttgagctg attgcggcta gctttctagt ttgctctttg atttttattg agtattagaa
     7561 aggagacctc atgacacttc cagttagaaa atccctacac gatgcagttt tacaggcttc
     7621 gaaagcggat acttgggaac aagctaccaa ggaatggaat gaagtttcct tgatttttaa
     7681 cggtatcggc cgtagcaatt gtgtctgtgg aaatgccatc aaatacgctt atgaactctt
     7741 taacggtgtc acaggccaac gcctctttcc aattggtagc gactgtgttc gtcattttca
     7801 tcgattgtcc cttgaccagc aattggaaga ggaagaaaaa ctgctcagaa agattgaaaa
     7861 tctaaccaga aaagctcaga aaaaggaaaa aatcaaggtc aataaaagtg actttgacga
     7921 gcgacttcta aaatggctct gggaaaaagg tgttttcaaa cccaatcgtg gcaatcaatt
     7981 tgcgcctgag agagactacc agcttttcct agaagtcttt cagggaggaa gttggaccaa
     8041 ggcggaacca aagaaaaagg ctcggatgga agaagtcctt gaaaagtgta tcaaaccctt
     8101 tttacttggg aaatcggatg accaactcta ccttgtcaag ctaggcaagg agaaaattga
     8161 ctacgaacaa gaactccgta tccaggcaga gaaagaacgc aagaagaggg ataaaatcgc
     8221 caagcaatat gcagacaatc tggttctagc catgggaccc gcagagcgtg cttatcaaga
     8281 ttactttggc tttacagaga ccctgactca agaagaacgc aagtgggaaa aaattctttt
     8341 tggtaaaaat agagcagaac gggctatcaa ggccaaacaa taccaaaaag agctggaaaa
     8401 agaccaacga attgccagtc aggatccaat tgaaagaaaa cagaatcaga cttggctcct
     8461 caattcctat tttcgtgagc ttcctgaaga aaaagctcga ttttctaggc tcttattaga
     8521 atatcgaaaa agtggtgaag tacccttttc aactgaatac ctgtcagatc atctcatcga
     8581 ctttttctat aaaatgaaag cctttgaatt tgaaatcgca ccagaacaag tccgagattt
     8641 tctaaaaaaa agcctgcagg aagaccatcg ctcatcagca caaggaagct ggatagaagg
     8701 aattctcctc aactgcctca aaccattttt agaacgatta gtgatatgag taacacctac
     8761 cgtgtaaatt tcatggtagg tgttattgta cccccaaata atataaaaca aagtatgaaa
     8821 gcgcatctca attttaagac ttttttgtaa attaagagta taattaaggt atactgcctt
     8881 ttttatagat aatagataat acactaatat aataaaggtc tttgtaacat atataaattt
     8941 tatttcaagg aggaataatg gaaaagtatt ttggtgaaaa acaagagcgt ttttcattta
     9001 gaaaattatc agtaggactt gtatctgcaa cgatttcaag tttatttttt atgtctgtat
     9061 tagctagttc atctgtggat gctcaagaaa ctgcgggagt tcactataaa tatgtggcag
     9121 attcagagct atcatcagaa gaaaagaagc agcttgtcta tgatattccg acatacgtgg
     9181 agaatgatga tgaaacttat tatcttgttt ataagttaaa ttctcaaaat caactggcgg
     9241 aattgccaaa tactggaagc aagaatgaga tgcaagccct agttgctggt gctagcttag
     9301 ctactctggg aattttaatt tttgccgtct ccaagaaaaa ggttaagaat aaaacggtat
     9361 tacatttagt attggttgca gggataggaa atggtgtctt agtttcagtc catgctttag
     9421 aaaatcatct tttgctaaat tacaatacgg actatgaatt gacctctgga gaaaaattac
     9481 ctcttcctaa agagatttca ggttacactt atattggata tatcaaagag gaaaacataa
     9541 cttctgagtc tgaagtaagt aatcaaaaga gttcaattgt cactcctaca aaacaacaaa
     9601 aggtggatta tagtgttaca ccgaattttg tagaccatcc atcaacagta caagctattc
     9661 aggaacaaac acctgtttct tcaactaagc cgacagaagt tcaagtagtt gaaaaacctt
     9721 tctctactga attaatcaat ccaagaaaag aagagaaaca atcttcagat tctcaagaac
     9781 aattagccga acataagaat ctagaaacga agaaagagga gaagatttct ccaaaagaaa
     9841 agactggggt aaatacatta aatccacagg atgaagtttt atcaggtcaa ttgaacaaac
     9901 ctgaactctt atatcgtgag gaaactatag agataaaaat agattttcaa gaagaaattc
     9961 aagaaaatcc tgatttatct gaaggaattg taagagtaaa acaagaaggt aaattaggta
    10021 agaaagttga aatcgtcaga atattctctg taaacaagga agaagtttcg cgagaaattg
    10081 tttcaacttc aacgactgcg cctattccaa gaatagtcga aaaaggtact aaaaaaactc
    10141 aagttataaa ggaacaacct gagactggtg tagaacataa ggacgtacaa tctggagcta
    10201 ttgttgaacc cacaattcag cctgagttgc ccgaagctgt agtaagtgat aaaggcgtac
    10261 cagaagttca accagcgtta ccgaaagcag tcgtaaccga caaaggtgag cccgctgt
//
LOCUS       DAVDFK010000053         9943 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.53, whole genome shotgun sequence.
ACCESSION   DAVDFK010000053 DAVDFK010000000
VERSION     DAVDFK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.53"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(51..1754)
                     /gene="ilvD"
                     /locus_tag="VUR04_001825"
     CDS             complement(51..1754)
                     /gene="ilvD"
                     /locus_tag="VUR04_001825"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET5341672.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1987..2919)
                     /locus_tag="VUR04_001826"
     CDS             complement(1987..2919)
                     /locus_tag="VUR04_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET5341673.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2916..3773)
                     /locus_tag="VUR04_001827"
     CDS             complement(2916..3773)
                     /locus_tag="VUR04_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5341674.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3777..5123)
                     /locus_tag="VUR04_001828"
     CDS             complement(3777..5123)
                     /locus_tag="VUR04_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5341675.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5136..5420)
                     /locus_tag="VUR04_001829"
     CDS             complement(5136..5420)
                     /locus_tag="VUR04_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5341676.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5424..7454)
                     /locus_tag="VUR04_001830"
     CDS             complement(5424..7454)
                     /locus_tag="VUR04_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET5341677.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7645..8652
                     /locus_tag="VUR04_001831"
     CDS             7645..8652
                     /locus_tag="VUR04_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET5341678.1"
                     /translation="MTEKLINSKPNGVFALILIELTIILGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8655..8855
                     /locus_tag="VUR04_001832"
     CDS             8655..8855
                     /locus_tag="VUR04_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5341679.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9007..9189
                     /gene="rpmF"
                     /locus_tag="VUR04_001833"
     CDS             9007..9189
                     /gene="rpmF"
                     /locus_tag="VUR04_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET5341680.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9205..9354
                     /gene="rpmG"
                     /locus_tag="VUR04_001834"
     CDS             9205..9354
                     /gene="rpmG"
                     /locus_tag="VUR04_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5341681.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9834..>9943)
                     /locus_tag="VUR04_001835"
     CDS             complement(9834..>9943)
                     /locus_tag="VUR04_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5341682.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3231 a         2106 c         1604 g         3002 t
ORIGIN      
        1 ctacggcaag gcgacgttga cgtgatttga agagattttc gagtatgagt ttatttttta
       61 cctgacttgt ccatattcca gaagtctgtc acggctccgc gtgaagcaga tgatacgatg
      121 tgggcatatt taccgaggac accacggctg taaagtggtg gcaaggttgt ttctgccttg
      181 cgtttttcaa gttcttcttc ggatacggcc atggaaattt ctttggtatc ttggtcaacc
      241 gtaacgatat cgccggtacg gagataggca attggtccac catcctgagc ttcaggagcg
      301 atatgtccaa caaccagacc ataagtacca ccagagaaac ggccgtccgt caagagggcc
      361 accttatctc cctgaccttt accaacaatc attgaagaaa gtgacagcat ctcaggcata
      421 ccaggaccac ctttaggtcc aacaaaacga acaacgacta catcgccatc aacgatttca
      481 tctgtcagaa cggcctgaat cgcatcttct tctgagtcaa agaccttagc tggcccaacg
      541 tgacgacgca ctttaacacc tgataccttg gcaactgcac cgtcaggagc aaggttcccg
      601 ttcaagatga taagcggacc atccgcacgt tttggatttt caagtggcat gataactttt
      661 tggcctggag tcaagtctgc aaagtcagcc aagttttcag ctacagtctt accagtacat
      721 gtgatgcgat ctccgtgaag gaaaccattt gccaacaagt acttcataac cgcagggaca
      781 ccaccgactt cgtagaggtc ttggaagaca tactgaccag atggtttcaa gtcggccaag
      841 tgaggcacac gttcttgaat cgtattgaag tcctcaagtg acaagtcaac atttgcggca
      901 tgggcaatgg cgagcaagtg aagagtggcg tttgtagaac caccgagagc catcgttaca
      961 gtaatagcat cttcaaaggc ttcacgagtc aagatatctg atggtttgag accaagttcc
     1021 aacatcttaa caacagcacg tcctgctgct tcgatatctt ctttcttatc agctgattca
     1081 gctgggtgag aggatgaccc tggcaaactc atccctagaa cttcgatagc agttgccatg
     1141 gtattagcag tatacatacc accacaacca ccagggccag ggcaggcatt acattcaaga
     1201 cgtttcacgt cctcagctgt catgtcaccg tggttccatt ttccgatacc ttcaaagaca
     1261 gaaaccaagt cgatatcttt accatcaaga tttcccggtg caatagttcc accataggcg
     1321 aaaatagctg ggatatccat attagcaata gcaatcatag atccaggcat gttcttgtca
     1381 cagccaccga tagcgacgaa ggcatccacg ttgtgaccac tcatagccgc ctcgatggag
     1441 tccgcgatga tgtcacgaga tgttagagag aaacgcatac caggcgttcc catagcgatc
     1501 ccgtccgcta cggtaatggt tccaaactgt acaggccaag cgcctgcaga tttgacacct
     1561 tctttagcca gtttcccgaa atcatgcaag tgaatgttac atggtgtatt ttccgcccaa
     1621 gtcgaaatca ctcccacaat cgatgtttca aagtccttat ctgtcatacc agtcgcacga
     1681 agcatagcac ggttaggtga tttaaccatg ctgtcataaa tgctactgcg gtggcgttta
     1741 tctaattcag tcatcttatc cctcccattt cagtttttac tattatagca caattttcgc
     1801 atgaagaaca gaataaaatt cttgaatttt cagaaaattc tatacacatg tgaaatattt
     1861 aaaattaaaa acaacaaagc ggattagtgc actttctgat gaccagaata tgctttttaa
     1921 tccgctttct ttaaataacg tactgtaatt tttacagaaa ttctttcaga taagtgtatt
     1981 taacatctat cttgcattat aaatttctag aaccttctct tttatattcg attcactcaa
     2041 accatactca ttaagaagat aatccatttt ccctacttga ccgaatcttt cttgaacacc
     2101 catccgatga atttttgtca ttccatcatc agagaataat tcacataaag aactgccaat
     2161 tccacctatc tgattgtggt tttctacagt aaatatagtt tttccactta acattgtttt
     2221 tatctgttct ggtatcggtt tgattctaaa taaatctatc acacctactg aataacctaa
     2281 tttagacagt tcatctgcaa ctcgaatact tggagcaacc attataccag aagcaacgat
     2341 tacaagatct tcaccatgcc ttaactcaat gtagccttta gaaaaatctt ctccaccttg
     2401 atacacagga actggagctt ttctaattgt tcgaatatat tttagtcctt ttaagtctaa
     2461 tgtctggttc aatatttcac gaaattggat atcatcagtt gcttcaaaaa taatcgattt
     2521 aggaattaaa cgtaacaatc caatttcttc aaatggcata tgtgtcccac cattcatttc
     2581 tgccgttact cctgcatctg atccaatcac agtggcatcc aattgtgcgt atccaagaga
     2641 aataaataat tgatcaaata ctcttcgtga agcaaaagga ccaaatgtat gaagataagg
     2701 tctaaacccc tgaatagaca agcctgctgc aaggccgacc atttctgctt ccataatccc
     2761 aacattcaca taacggtctc cgaagtcctt ttcaagatta tgagtagcca tcgaacttga
     2821 caaatcggct tctaagacta ctatatcaga ataactttga ttagcctcta aaaggaagtc
     2881 tctatataca tgccgtaatt ctttcgtact tctcatcatt ctgtttcctc caattcctga
     2941 cttaatcttt ctacaactga agttaacatt tgtttctcct ctacagtagg gcgaagatga
     3001 tgattggatt tcatttcttc cagctcttga accccttgac ctttaatagt atctaataca
     3061 atgcacttag gtgatgaatt atttgactgt tttaattgga caatcccttc ataaatttct
     3121 ctaatatctg aacccttgac cctaatggat tcaaatccaa atgctgaaaa tttttctacg
     3181 aaatcacctg gattacaaat atcctttgta aaaccatcta attgtttttt gttctcatca
     3241 acaaatacaa ttaagttgga taactgttga tgagaagcaa actgtatagc ctcccaacat
     3301 tgtccttcat ttaactcacc atctccaaca atagcataag tataaaaggg actctttctt
     3361 attctctgac catatgcaag tccagttgca acactaattc cttgtcctaa agagcccgtt
     3421 gtcatatcta tgcctggcgt tagatttcta tcaggatgag acggtaattt ggttccattt
     3481 gtatttaaag aatataggaa ttctttgtca aagaaaccat tcaaatagag tgtactgtat
     3541 agagctggtc ctccatgacc ttttgataat atgaaataat ctctatctcg tgctgcaaat
     3601 atttctggag tcattggcat tatttcacca taaagcactg ctaaaacttc tacgatagac
     3661 agacttcctc cgtaatgtcc gaatccaaga tgattcaatg ttctaagagt atttaatcgg
     3721 atgttagtcg caaattttct taactcatct tctctatttt tacttaaaat catcccttat
     3781 tcctcctttg cagatggctt tttaataaag gatactccaa acataactgc tagaataaga
     3841 acaagaccaa tcacaatgcc tgcttgtgag ccaaattgat ttaacattcc taaaataatt
     3901 cctgatagac caaaatctgc atctgagaaa gttgatcctt ggaaaccaag tcctcccaaa
     3961 actggcatta aaaagactgg aagaaaactg attaaaatac cttgtaaaaa tgctccaata
     4021 gtggctccac gaacaccacc agatgcattc ccaatgacac ctgcagtcgc tccacagaag
     4081 aaatgaggca caacacctgg taagataaca accgttcctg aagcaatcat aattgccata
     4141 cttactaaac caccaataaa actagagata aatccaatta gaactgcatt gggtgcataa
     4201 gtataaacaa tcggacaatc caaagcaggt tttgaattag gtacaagacg ctctgaaata
     4261 cctttaaagg ctggaacaat ttcgcccaaa ataaggcgaa cacctgctaa aataacaaat
     4321 acccctgctg caaattgacc tgctaattgt aaagcataaa ctagaccact tgtaccacta
     4381 ctgatttctt tttctatata ttctgaccct gcaaagatag ctacaataat gtaaataact
     4441 gccatagata aagtgatact aacagtacta tcacgtaaaa aagctaaact ctttggaaat
     4501 ttaatgtcct ctgttgattt tgatttgtca ccgataaggc taccagtaaa accactcaac
     4561 caatatccca aagaactgaa atgacctaaa gccaccttgt catttccagt taattgaacc
     4621 atatattttt gcacaaatgc tggggaaata ctcataataa taccgagtgc taatcctcct
     4681 agtaagatga gaggcaagct agtaaagcca gcaactgata aaatgaccgc aatcatacat
     4741 gccatatata gagtgtggtg ccctgttaaa aaaatatatt taaatcgagt aaaacgagcg
     4801 attaagatat tgaacaccat gcctgcaaac ataatcattg cagtagctga gccatatgtt
     4861 gttaaagcta cagctacaat tgcttcatta ttcggcacaa cgccagataa atgaaaagca
     4921 tgctcaaaca tggtaccaaa tggatttaaa gaattttgta caattcctgc accaccagat
     4981 acaactaaga aaccaacaaa ggtcttaatt ccacctttaa taatatcagg taatttcttc
     5041 ttctgaagaa ctaatcctaa aattgcaatt aaagctacta aaatagctgg tgtactaaca
     5101 atatccaata tgaacttcat catgacgcta gcctcctata taagtccttt ttcttcacaa
     5161 agtttagtaa ttaattctcg tagttcatcc atatcaataa tactatttaa gatacgaaca
     5221 tctccaagat gactagctga atcagctaga tcacgaccaa caatccaaat atcagctgca
     5281 tttggatctg ctccacctaa atcataatgt tcaacttcta catccgaaac attcaaatca
     5341 ctcaatacag attcaatatt catctgtacc ataaaacttg aacctaatcc tgaaccacaa
     5401 gctgtaccaa tttttaacat tatctaatcc tcctgtttaa ttatcatttt aatgtcatca
     5461 tagttttttg atgaaattaa agtttgaaca tgatttttat ctcttaaaat tgttgttaaa
     5521 tgtgacaaag cctttaaatg actctcatta tcaatggctg caatacaaat caacaatctt
     5581 acctcttgtt ctggattatc caataaataa atcggttctt ccaaaactaa cattgacatt
     5641 cctatttcat tcacaccttc atctggccga gcgtgaggaa ttgctactcc cttccctaaa
     5701 ttaataaaag gtccaaactc ttctactttt tgaatcattg cctcagggta gttctccgtt
     5761 atcttatctt gatccaaaag cggtttagct gctaaacgaa tcgcctcctt ccatcctaat
     5821 ttttgcgaac taacctgata ggtttctttg gtaataagtt gttctagcac tggtacaatt
     5881 tcctttctat catttttttg ataaagataa ttctttaacg ccaatcttaa ttccaattct
     5941 tgtgtaataa ttccatatct tttgacaata ttcaggattt gttcaatctc aaaatctcca
     6001 tactctaaat tcggaaaatc ttttaacact agttctacta gttgtattgc ttgctcttca
     6061 gtcatcataa ccgaaactag ataatttggc ttttctgtct ccacctttat ggtagaaaaa
     6121 accatatcat agtcactact agctttcacc tgtaaatcat caatctttga ggttcctata
     6181 aactcaattt gaggaaataa tgctaataga ttctctttta acatcaatga agaactaaca
     6241 ccattaggac aaatgattgc tgctttatac catttttgag gcaaagtatc tgctttcttt
     6301 aaataacctc cgaaatggat aacaaaatat gctgtttcac tatcaggtat aggattgtca
     6361 atagcgtcca tcaagggcat caaagaatct ttgactaatt caaataaatc aggataatgt
     6421 tctttaacat gcaatacata ttcatttgaa ctaggtaggc cgaactttaa tctatagtaa
     6481 gccggtataa ggtggcgacg aagattttct ctcaatcctt ccctttgttt aaaatgtaac
     6541 aaagaaatat cttccattct acttataata gcctctgtta attgattaaa gtaaaccgga
     6601 gcaacatcta cttcaccttc aaagcaactt gataataaaa ctgtgatata gcgataatca
     6661 tcctcagaaa acaccgtatc tataattccc aaatcaacca ctgtatccaa taaaatagtc
     6721 gttatatctt gaataacagg agatactaat gtctctgaaa gacatactct ttcaacatcc
     6781 ctttgatacc tacacagaat gaatactaaa ccgaaaaggt aaacttttaa ttgattaaca
     6841 ataggtacta gctgtagctt ctcataataa tctttaacta cctgatcaat caaatcataa
     6901 gttaatgaat acccccaact ggataaaaca taatccaaac cccaaatccc tatggaggat
     6961 tccagcaact cactaaccat ttgaaaagct aaacggtgct tattccactc tgaaccgtgt
     7021 aaagtataac cttttgctct actgtaccct agctccaaat cattatctaa cataatcttt
     7081 cttaatgatt gaatatcaga taaggttgta ttcttactta ctttcaaaaa gtcttggtaa
     7141 tgattattcg atataaaatc taatcggcaa aaagtgtaaa gatagattaa agctaagcga
     7201 gtcgactttg gtaaaaccaa ttcatccgac ttaataatat ctgtcaaaga ctgcttcgta
     7261 cgatttgata aactatagcg accttgtttt ttatccagca ctatcccttt attagctaga
     7321 taaggcacta aataatctat tccttctttg acttccttta taggtaagct caccttaaca
     7381 gataattcat ataatgatag ctcacaatga tccatcaaag tcatcaaaat aactagtgct
     7441 ctataatcaa acatttctct tcctttctaa ctacaattat agtgtaaaaa ttataagaat
     7501 aaaagagtat ttgagcacaa tataatctca ccttttaaaa gaaattattg ggctgaaagt
     7561 ttttagtgat tattttcaac tttctattga cttttaaaaa caaagtgata tcatttagat
     7621 atcaaataat gggaggtcat tcttatgact gaaaaactaa tcaattcaaa accaaatggt
     7681 gtattcgcat tgattctcat tgagttgaca atcatacttg gtatctttat atttataatg
     7741 ggtgttggtt cggaaaacat ttttggaatt attatcggac ctttactaat cgtaattgca
     7801 ggtctagctc atgctggttt aaaagttgtc aaacctcagg aagctctggt tctgacacta
     7861 tttggtaatt atacaggtac catcaaagaa cctggttttt actttgtcaa tcccttcagc
     7921 gtagcagtca accctgcaaa ccacactcga cttggacaaa gtggtgatgt tagcacaaaa
     7981 tctccttttt taggagctaa atcatcaaat gacaatgatg taaatcttga aattggcaag
     8041 aaacacattt ccctcaaagt catgaccttg agcaattctc gtcaaaaaat caatgattgc
     8101 ttaggaaacc ctgtagaaat cggtatcgcg gtaacttgga gagttgtcga taccgctaag
     8161 gcagtcttca acgttgataa ctacaaagaa tatctttcat tgcaatgtga tagcgccctc
     8221 cgtaatattg tccgcatcta tccttacgat gtgtctccta atgtggatac tacgggtgac
     8281 gggcaagcag atgaaggtag tctccgtggc tctagcgaaa ttgttgctaa ccgtattcgt
     8341 gaagaaatcc aaagtcgtgt tgaggatgct ggcttggaaa tccttgaagc acgtatcact
     8401 tacctagctt atgctccaga aattgctgcc gttatgcttc aacgccaaca agcatctgcc
     8461 attattgatg cacggaagat gattgtagat ggtgctgtag gaatggttga aatggcacta
     8521 gaacggctca atgaagggga attggtagaa cttgacgaag aacgaaaagc tgccatggtt
     8581 tcaaatctcc ttgtcgttct ttgtggcaat catgatgcac aaccaattgt caacacagga
     8641 agtctttact aaagatggct gaagctaaaa aaaagcagat cccccttcga ctctcaacaa
     8701 agttatacgc tgcactcgca tcatgggcag aagacgactt tcgttcagtc aatgggcaaa
     8761 tcgaatatct cctcacagag tgtgtcaagc aacggaaaaa agacggaaaa tacgtatcag
     8821 aaaccattga cgaaccattt gagattgata tttaacacct tctcctgtct gccgtgtcgg
     8881 ataggagaat tttttcatct ttttttgtca agtaacttta ctttacaaaa aaaatgtgtt
     8941 atcctagtat ggttgatgaa aatcagtaga ttgaatcgaa tataaatacc taaaggagaa
     9001 atcaaaatgg cagtacctgc acgtcgcact tcaaaagcga agaaaaacaa acgtcgtaca
     9061 cactacaaag taacagctcc atctgtaaac tttgacgaaa ctactggaga ttactcacgt
     9121 tctcaccgtg tatcacttaa aggatactac aaaggacgta aaatcgctaa agctgcatca
     9181 gctgaataat agaagggaga taccatgcgc gtaaatatta cacttgaaca caaagaatct
     9241 ggtgaacgct tgtaccttac ttctaaaaac aaacgtaaca ctccagaccg ccttcaattg
     9301 aagaaatact caccaaaact tcgcaaacac gttgtgttta cagaagtgaa gtaagcattc
     9361 aatacgaatc aatacagaag aaaaacgctt gatcagcgtt ttttcttttt gttaatttca
     9421 ctatattgca agagaaatca ttcgaatgac tacatttttt gaaataagaa tacggattcg
     9481 gacgattaaa agtaagagaa actcaaatgt aagttggggt tccttttttg tatatttttc
     9541 aaataacgcc tctacactat ttgtagcaaa ttcaccaact acagttgcat cttagttaaa
     9601 ataagttaga atatgtaagt gagtaccaga tataccaaga catcgtcacc atctaaggta
     9661 tattcaaaat acaaaagttg accaactaga tttctgaata tccttatata tccattctta
     9721 aaattggttt aaatagcgta gtcttttaaa ctagttttga gaatccaaaa aatcttccta
     9781 catatgtaag aagatttttt agttcagaat gattagattt agctaatgga tacctatcct
     9841 acccactcac cgttagcatt gactcgatag ccatcgggtg tagtcgtgtt tactaataaa
     9901 tctcctgaat tataggtata gtaccattta ccagaaactg taa
//
LOCUS       DAVDFK010000054         9550 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.54, whole genome shotgun sequence.
ACCESSION   DAVDFK010000054 DAVDFK010000000
VERSION     DAVDFK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.54"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..4155
                     /locus_tag="VUR04_001836"
     CDS             <1..4155
                     /locus_tag="VUR04_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HET5341683.1"
                     /translation="ESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTG
                     VQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENEASSTNGESERPKDKIKEEKQVDK
                     KLELRNVSNVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIEST
                     TKNNKEVYKIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDP
                     NGTFHLGATMDAREVELPDDQESYVKNEFYGKLIGENNGKYYAIYNLKKPLFKTLNTA
                     TIQNLSIKEANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRI
                     SNSSFTGRITNTYDTTVGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGI
                     AGVVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNV
                     TNGNAISGDNFDNMKEDHAYSSKGNKVVNVVQVDDELVTKDSDVQRGTVLDADKVKEK
                     KAELVSKHSTKVEDFDFTSRYTTIYNEVTGYQKSREQVYKNIEKLLPFYNRETIVKYG
                     NLVDESSELFTKELLSVVPMKNNEVITDINKNKQEINKLLLHFEGNKSQVLNIAYKND
                     FSKVAEYSIEYQGLLYTPNTLLHDYSNIVDNVLTDLNSVQYDSNAIKKILDISDKVKN
                     TELYLDEQFVKTKANIKDTLSKLLSADAAIAENSNSIIDNYVIQKIKQNKEALLLGLT
                     YLERWYNFKYGETKAKDLVMYHLDFFGKSNSSALDNVIQLGKSGFNNLLAKNNVITYN
                     VLLSKNYGTESLFKALEGYRKVFLPTTSNNEWFKAQTKAYIVEEKSSIPEVSKKQSEQ
                     GTKYSIGIYDRLTSPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSKVHP
                     KGDNLNKFVEDNVREAAKRFRDHYDYWYKILELENREKLYRSLLVYDAFKFGRDNTED
                     KVTYQADFETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTH
                     EMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTR
                     LQVADPTQRFNSAEDLHNYMHNMFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYK
                     QDPDGNSVYATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLF
                     SPIYSALSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKIKSY
                     GKEVGLVTDKLVLEKVFNNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNVSWGRTN
                     RITITSIANLQNMINTAVNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQTNDFRRS
                     IFENKK"
     gene            4199..9550
                     /locus_tag="VUR04_001837"
     CDS             4199..9550
                     /locus_tag="VUR04_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5341684.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSLLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKG
                     EPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVH
                     EKLAYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVASEREELPSLHTDIRTE
                     TIPKTTIEESDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMK
                     PEIIVKGTKERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDG
                     DTVVKRVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKV
                     EIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEE
                     VTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNT
                     DKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGT
                     VTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQG
                     TLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQN
                     SGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIF
                     YGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLG
                     ITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQ
                     GNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKV
                     KQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEEN
                     TDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENK
                     AKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDR
                     TLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDF
                     VNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNE
                     FKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMG
                     YDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGIS
                     AFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHR
                     ENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKI
                     DREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGR
                     YRPEDFKPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVS
                     SKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDG
                     QTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
BASE COUNT         3553 a         1364 c         1899 g         2734 t
ORIGIN      
        1 gagtcgccag atactgtggt aagtgataaa ggtgaaccta aacaggtagc accgcttcca
       61 gaatatacag gaccacaagc cagcgctatt gttgaaccag agcaagtagc accactacca
      121 gaatacacag gggtacaagc cggatcgata gtcgagccag agaaagtaga agcaccgaaa
      181 gaatatactg gtaaaatcga acaacctagt gcagaagata ctaaacctga aaatgaggca
      241 agctctacaa atggggaatc ggaacgtcct aaagataaaa ttaaagaaga aaaacaagtc
      301 gacaagaaac tagaacttag aaatgtttca aacgtggaat tatatacggt agaaaataat
      361 aaatatcgac atattacggc tgtagatggt gctttagata gttcattgaa gtatttcatg
      421 aaggtaaaat cagaaaattt taaagatata atgttgcctg ttactaaaat tgaaagtaca
      481 acaaaaaaca ataaagaagt atacaaaatt gtggctcatg cagaaaatct aattcaacac
      541 gaaaacaatg ttatttcgaa tgactataca tattatttac caaaaactca gcaaagtgaa
      601 actggcgtct atacatcatt taaaaattta gttgatgcaa tgaatagtga ccctaatgga
      661 acattccatt taggtgcaac tatggatgct cgtgaagttg aacttccgga tgatcaagaa
      721 agttatgtaa aaaatgaatt ttacggaaaa ttaataggtg aaaataatgg taagtattat
      781 gctatttata acttgaaaaa acctttattt aaaactctaa acaccgctac tattcagaat
      841 ctttcaataa aagaagcgaa tgtttcttct aaagaagatg ctgctacaat atcgaaagaa
      901 gcaaaataca atactcttat agataatgtt cattctgatg gtattatagc tggtgaacgt
      961 ggaattggtg gattggtttc aaaagtagat aactcgagaa tttctaatag tagttttaca
     1021 ggcagaataa ctaacacata tgatacaact gtagggtatg aaattggtgg tttagtaggt
     1081 aaactttctg gttcgcttgc ttctatagag aaatcaatag catcgattga catagcctct
     1141 aatgcaaaat caggagatca aattgttggt ggtatagccg gagttgttga gaaaagtgcg
     1201 acaattaagt atagctatgt tgaaggaaat gttaacaatg tgcgacactt tggtaaagtt
     1261 gggggagttg caggtaatct ttgggataga gattcacaag atgtaagtaa atcaggtaaa
     1321 ctatcatatg ttttaagtga tgttaatgta acaaatggta atgctatatc gggtgataat
     1381 tttgataata tgaaagaaga tcatgcttat agtagtaaag gcaataaagt agtaaatgta
     1441 gtccaagtag atgatgaact tgtgactaaa gattcagatg tacaaagagg tacggtatta
     1501 gatgctgata aagtaaaaga gaaaaaggca gaattggttt ccaaacacag cactaaagta
     1561 gaagattttg attttacttc aagatacact actatttaca atgaagtaac aggttatcaa
     1621 aagtcgagag aacaagtata taaaaatatt gaaaaactat taccgttcta taatcgagag
     1681 acaattgtta aatatggtaa tttagtagat gaaagcagcg agctatttac taaagaactt
     1741 ctatcagttg ttcctatgaa gaataatgaa gtaataactg atattaataa aaataaacaa
     1801 gaaataaaca aattgttatt acattttgaa ggtaataaat cacaagtatt aaatattgca
     1861 tataagaatg atttctctaa agttgctgag tatagtatag agtatcaagg attattatat
     1921 actcccaata ctctattgca tgactacagt aatattgtag ataatgtttt aactgacttg
     1981 aattctgtac aatatgattc aaatgcaatt aagaaaatat tagatatctc agataaagtt
     2041 aaaaatacgg aattatactt agatgagcaa tttgttaaaa caaaagcaaa tataaaagat
     2101 actttatcaa aacttctgtc agcggatgca gcaatcgctg agaatagtaa ttcgataatt
     2161 gataattatg ttattcagaa aatcaaacag aataaagaag ctttattgtt aggattaaca
     2221 tacttagagc gttggtacaa ttttaaatat ggtgaaacga aagcaaaaga tttagttatg
     2281 tatcacttgg atttcttcgg taaatctaat agttctgcat tagataatgt tattcaatta
     2341 ggtaaatctg gatttaacaa tttactagca aaaaataatg taattactta caatgtatta
     2401 ttatctaaaa attatggaac tgaaagttta tttaaagcat tagaaggata tagaaaagta
     2461 ttcttaccaa caacttctaa caatgagtgg tttaaagctc aaactaaagc atatattgtt
     2521 gaagaaaaat cttctattcc agaagtaagt aaaaaacaat cagaacaagg aactaagtat
     2581 tctataggaa tttatgatag attaactagt ccgtcatgga aatatcaaag tatggtctta
     2641 ccactattaa ctttacctga agaaaaaaca gtatttatga tagcgaatat ttcaacaata
     2701 ggatttggtg cttatgatag atatagaagt aaagtccatc ctaaaggaga taacttaaat
     2761 aaatttgtag aagacaatgt aagagaagct gcaaaaagat ttagagatca ttatgattat
     2821 tggtataaaa tattagagct tgagaataga gagaaacttt atagaagttt attagtatac
     2881 gatgcattta aatttggtcg agataatact gaagataaag taacttatca agctgatttt
     2941 gaaactgatc atccagctat aaaatacttc tttggacctg cggggaataa tgttgttcat
     3001 aatggacacg gagcatatgc taccggagat gcattctatt atatggcata tcgtatgttg
     3061 gataaagatg gagctgtaac atatactcat gaaatgacac ataactctga tagagaaatt
     3121 tatcttggag gatatggaag aagaagcgga ttagggcctg agttttatgc taagggctta
     3181 ttacaagcac ctgaccaccc atatgatcca acaataacaa ttaactctgt gttgaaatat
     3241 gatgattcag aaaattcaac aagacttcaa gtagctgatc caactcaacg atttaatagt
     3301 gcagaagacc tacataatta tatgcataat atgtttgatt taatatatac tcttgaaata
     3361 ttagaaggtc gtgctgtagc taaattagat tataatgcga aaaatgattt attaagaaaa
     3421 attgagaata aatataagca agatccagat ggtaattctg tttatgcgac aaatgttgtt
     3481 cgcagattaa cgatggatga agttaataaa ttaaattctt ttgatagttt aattgaaaat
     3541 gatattatta ctagcagagg gtacaaagac caagaatata agagaaatgg ttattataca
     3601 attgatttat tttcaccgat ttattcagct cttagtggag agaaagggac tcctggtgat
     3661 ttaatgggac gtcgtatagc attcgaatta ttagctgcaa aaggatataa agagggcatg
     3721 gtaccttata tctcaaatca atatgaaaaa gatgcaaaag ctgcgggaag taagattaaa
     3781 tcttatggta aagaagtagg tttagttaca gataaattag tacttgaaaa ggtatttaat
     3841 aatcgttact catcttgggt agaatttaaa aaagcaatgt ataatgagcg aatagctaaa
     3901 tttaataatc taataagtgt tagctttaat aatccaaatg taagttgggg aagaactaat
     3961 agaataacaa taactagcat agccaacctt caaaatatga taaatacggc tgtcaatgaa
     4021 gatgctgaag attttagagc acaattatac cctgatacaa atagtagagt tcttaaactg
     4081 aaaaaagcaa tatataaagc ctatcttgac caaacaaatg attttagaag atcaattttt
     4141 gagaataaaa aatagtgttt actattagga aataaaaagt gaatgtggag gattagaatt
     4201 gtcattatta aaaaaagata aattttccat taggaaaata aagggtattg ttggttcgat
     4261 attcttgggg agtcttttat ttgcactgtc agttgttggt gtatcgactt atcattactt
     4321 agattatagt actttgacac aaactgaacg tgatcaactc aaacaaggta gacctgatga
     4381 atcaaaagag tcatatgctt tggtttatga aaaagacgca ttaccaaaca caggaagttc
     4441 tcaatctatt atgactgtat tgggtttgtt agctatcggg agtcttattg tgattatcac
     4501 aaaagataaa aagaggaaaa aaatagctac atttttgatt gtaggggcga caggtttagt
     4561 tacactatca actgcttcag cacttaattt gaatgctaac atccatgagt ctggacgtga
     4621 tggtgtgttg caaatttctg gttacagata tgttggttac ttggagcttg atgatagaac
     4681 tgtttcgtcg gtttctccag catcaactgt ttctccagtt gagcaaccca aagttgtgac
     4741 cgacaaaggc gaaccagaag ttcagccagc gttaccagaa gcagttgtaa ctggaaaagg
     4801 gaaaactgaa gtacaaccga cattaccaga agctgttgtg actgaaaaag gggaaccgga
     4861 agtacaacca gccttacccg aagcagttgt aactgaaaaa ggcgaaccgg aagtacaacc
     4921 agccttaccc gaagcagttg taactgaaaa aggcgaacca gaagttcatg agaagcctga
     4981 ctatacgcaa ccaataggtg caaaccttgt tgagcctgaa gttcatgaga aactagcata
     5041 cactgaacct gtaggtacaa caggagtaga tgaaaatgga aacttgattg agccacctgt
     5101 tagcgatatt ccagagtata ctgaaccaat atctacagtt tcagaagttg catcagaaag
     5161 agaagagttg ccttctttac ataccgatat tcgtacagag actattccta aaaccactat
     5221 agaagaatct gatcctagca aatttatagg cgataattct gttaaacaag ttggtgagga
     5281 tggcgaacgt caaattgtta ctagctatga agagttacat ggcaaaaaaa tcagcgagtc
     5341 agttgaaaca gtaacaattt tgaaagaaat gaagcctgaa attattgtaa aaggtacaaa
     5401 agaaagacca aaagaaaaaa cggctcctgt tttaaccttg accaaagtaa cagaagatgc
     5461 tatgaatcgt tctgccaact taaattatga gcttgataat aaagataatg ctgaaatatc
     5521 aagtattgta gctgaaatta aagatggtga tacagtagtt aaaagggttg atttatctaa
     5581 agaaaaatta actgacgctg tacaaaattt ggatttgttt aaagattata agattgcaac
     5641 aacaatgatt tatgatcgtg gtcaaggttc tgaaacgtct aaactggatg aaagacctct
     5701 gcgtttggag ttgaaaaagg tcgaaattaa aaatatcgca tctactaatt tagtgaaggt
     5761 aaatgatgat ggtactgaaa cacctagtga ttttatgaat gaaaaacctt cagaagaaga
     5821 tgttaaaaaa atgtacttaa aaatcactag tcgcgataat aaggtaactc gtttaactgt
     5881 agactctatt gaagaagtga ctgaagaagg tcaaaaactt tacaaaataa ctgctgaagc
     5941 acaagatttg attcaacaca cagacccaac gaaggttcgt aataagtatg tttattatat
     6001 agaaaaaccc catcctaaag aagataatgt ctactataac tttaaagatt tagtagatgc
     6061 tatgaatact gataaaaatg gtacatttaa acttggtgca gatttgaatg ccactggtgt
     6121 tccaacacct aagaaatggt atgttgacgg cgactttaga ggtacattga agagtgtaga
     6181 ggggaaacat tatactatcc acaacacgga gcgtccgtta ttccagaata ttattggtgg
     6241 tacagtaacc aaagtaaatc tgggaaatgt aaatatcaat atgccatggg cagaccgcat
     6301 cgcaccgatt gctgacacta ttaaaggtgg cgctaaaatt gaagatgtca aagtgactgg
     6361 taacgtatta ggtagaaact gggtatctgg atttattgat aagattgaca accaaggtac
     6421 actcagaaat gtagccttta tcggaaatgt gacatctgta ggtgatggtg gtcaattctt
     6481 gaccggtatc gttggtgaga actggaaagg actagtcgaa cgtgcgtatg ttgacgcaaa
     6541 tcttattggc aagaaagcca aggctgctgg tattgcttat tggacacaaa acagtggtga
     6601 caatcataaa gttggtgtcg aaggtgcagt caagaaagga attgtgaagg gtaccattca
     6661 ggtagaaagt cctgttgaag tcggcggtgc tgttggacgt ttgagtcatc atggttatat
     6721 cggggaagtc gtatctatga tgaaagttaa gaagggtgaa attttttatg gttctagtga
     6781 tatgaatgat gacccatatt gggtggcgaa taatgtacga ggaaattatg tcgttaatgg
     6841 tgtgagtgaa ggtacgatat cttatgctcg tgctaaagaa caccatcgta tcaaaccaat
     6901 ttcacagtca gaagcagata ctaaaattat gatgttaggt attacagcac aagattttgc
     6961 tatcaacgaa cctgtggtca atcgcttaaa ccgtttaacc agaaaagaag atgaatataa
     7021 gtcaacccaa gactataaag tagatcgaga tctggcttat cgtaatattg agaaacttca
     7081 accattttat aacaaagaat ggattgtcaa ccaaggtaac aaacttgcag aagattcaaa
     7141 cttagctaag aaagaagtcc tttctgttac gggtatgaag gatggacagt ttgtaactga
     7201 cttatcagat attgataaga ttatggttca ctatgctgat ggtactaaag aagaaatgga
     7261 cgtcactaag aatgctgatt ctaaagtgaa acaagttcgt gaatatacca tcgctggaca
     7321 aaacgttgtt tatacaccaa atatggttga gaaagaccgt aaccaattga ttcaagatat
     7381 caaagataag ttggcgtcag ttcaattgat ttctcctgaa gtacgtgctt tgatggatgc
     7441 acgtaagaaa ccagaagaaa atactgatga acgtaagaat ggttatatta aagaccttta
     7501 cttagaagaa agctttgctg aaacgaaagc taatcttgat aaattggtta aatccttagt
     7561 tgaaaatgca gatcatcaat taaatagtga cgaagcggct atgaaagcac ttgttaagaa
     7621 ggtggatgaa aataaagcta aaatcatgat ggctctgact tatctcaatc gttactatga
     7681 tatcaagtat ggggatatga ctatcaagaa cttgatgatg tttaaacctg atttctatgg
     7741 taaatcagtt gaccttcttg atttcttgat tcgaattgga tcaagtgaga gaaatatcaa
     7801 aggtgacaga actttggatg cttatcgtga tatgattggt ggaactattg gtaagtctga
     7861 attacatgga ttcttagatt acaatatgcg tctcttcact aacgatactg atttaaatga
     7921 ttggttcatc catgcagcta agaatgtata tgtatcagaa cctcaaacaa cgaacccaga
     7981 ttttgttaat aaacgacatc gtgcatttga tggtttgaac aacggtgttc ataatcgtat
     8041 gattctacct ctattaactc ttaagaatgc acatatgttc ttgatttcaa cttacaatac
     8101 aatggcttat agttcttttg agaaatatgg taagtataca gaagaagcta gaaatgaatt
     8161 caaaaaagaa attgataagg ttgcacatgc tcaacaaaca tacttagact tctggtcacg
     8221 tttagcattg ccaagcgtac gtgaccaatt actcaagagt gagaataggg taccaactcc
     8281 tgtgtgggat aaccaaaact atagtggtat taaaggaata aaccgtatgg gttatgatga
     8341 gaagaaagta ccaattgcgc caattcgtga gttatatggt ccaacttgga aattccataa
     8401 taccaactgg aatatgggag ctatggcatc tattttccca aatcctaata acaatgacca
     8461 agtttatttc atgggaacaa atatgattag tccgtttggt atttcagcct ttactcatga
     8521 aactacacac gttaatgata gaatgcttta cttcggtggt catagacacc gtcaaggtac
     8581 agacgtcgaa gcctatgctc aaggtatgct acaaactccg tcaagtattg gtcaccaagg
     8641 tgaatatggt gctttaggtt tgaacatggc ttatcatcgt gaaaatgatg gtgaccaatg
     8701 gtataactat gaccctgata agcttcaaac tcgtgaagat atcgatcgat atatgaaaaa
     8761 ctataatgaa gcactgatga tgctagatca tgtagaagca gacgccgtac ttccacaatt
     8821 gaatggtgat aatagcaagt ggttcaagaa aattgataga gaaatgcgca gaaatcttgg
     8881 ggatggtttg aataacttag tagcaccgca ccaatgggac aacgttcgtg acttaaatca
     8941 agaagagagt tctaagaaat tatcaagtat taacgatttg attgataata atttcatgac
     9001 caaacacgga aatccaggta acggacgtta tagaccagag gattttaaac caaactcagc
     9061 ttacgtaaat gtcaatatga tggcaggaat ttacggtggg aatacgagtc aaggtgctcc
     9121 tggttcatta tcgttcaaac ataatgcctt ccgtatgtgg ggttattatg gatatgacaa
     9181 aggtttcact agttatgtat ctagcaaata tcaaggtgaa gctgataaac aaaaccaggg
     9241 tagattaggt gatgatttca ttatcaaaaa agtttcaaac aaccaattct caaatcttga
     9301 agattggaag aaatattggt atcatgatgt gaaatccaga gctgaaaaag gattcacaga
     9361 gattacaatt gatggacaaa ccattcacaa ctataatgaa ctgaaagact tattcgacaa
     9421 agctgtcaca gaagacctca agaaagctgg aaactactca aatactgaga atttgaaatc
     9481 caaagtcttc aaagctcttc ttaaaaacac agacggtttc tttaatccat tgttcaaaaa
     9541 agacatttaa
//
LOCUS       DAVDFK010000055         9053 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.55, whole genome shotgun sequence.
ACCESSION   DAVDFK010000055 DAVDFK010000000
VERSION     DAVDFK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.55"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..716
                     /locus_tag="VUR04_001838"
     CDS             <1..716
                     /locus_tag="VUR04_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5341685.1"
                     /translation="GWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQ
                     YNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYNDSWYYLNSNGAMATGW
                     LQYNDSWYYLNSNGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMAT
                     GWAKVNGSWYYLNANGSMATGWVKDGDIWYYLEASGAMKASQWFKVSDKWYYVNGLGA
                     LAVNTTVDGYTVNENGEWV"
     gene            1117..2238
                     /gene="mnmA"
                     /locus_tag="VUR04_001839"
     CDS             1117..2238
                     /gene="mnmA"
                     /locus_tag="VUR04_001839"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET5341686.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2379..2834
                     /locus_tag="VUR04_001840"
     CDS             2379..2834
                     /locus_tag="VUR04_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5341687.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKTQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2844..4757
                     /gene="mnmG"
                     /locus_tag="VUR04_001841"
     CDS             2844..4757
                     /gene="mnmG"
                     /locus_tag="VUR04_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET5341688.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(5137..6816)
                     /locus_tag="VUR04_001842"
     CDS             complement(5137..6816)
                     /locus_tag="VUR04_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET5341689.1"
                     /translation="MTYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6818..7051)
                     /locus_tag="VUR04_001843"
     CDS             complement(6818..7051)
                     /locus_tag="VUR04_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET5341690.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7289..7432
                     /locus_tag="VUR04_001844"
     CDS             7289..7432
                     /locus_tag="VUR04_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000407001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341691.1"
                     /translation="MEIVDLRKNTVLVSLIVGLDGWDRMISLKKEKALEKSREQTKRL
                     RQN"
     gene            7900..8175
                     /locus_tag="VUR04_001845"
     CDS             7900..8175
                     /locus_tag="VUR04_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5341692.1"
                     /translation="MNEIVETTLLLNLFYYQNETYSRNEVFIESKKRKAISILDEYAD
                     ELKEIDEDLYNEYKETITFLEGISEEEYQNIKNEIIESVKEFIKNER"
     gene            8252..8749
                     /locus_tag="VUR04_001846"
     CDS             8252..8749
                     /locus_tag="VUR04_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341693.1"
                     /translation="MKTKFGQTKGGYIDFAKVCSSQGEYISKDEQHYKNYEVLKNCIE
                     KNLFEEYELSYLRKMSDISILDLNLDDKCEPNQKWHLYVSLFAQTIIEIKNEGKTAED
                     LWTTEFRKYLSLQLKLWMAEVVGLDVQEIGDAIKNSAGKSKVNNLIKEISWDAIFEIV
                     YKESI"
     gene            8769..>9053
                     /locus_tag="VUR04_001847"
     CDS             8769..>9053
                     /locus_tag="VUR04_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341694.1"
                     /translation="MDLIERLLEERNTKLHGGIYDITQKRFAYHSNKIEGSSLTENQV
                     SFIYDTKIIANIGERGIRIDDVIEMANHFKCFDYILDTVNEPLTEAYIKKI"
BASE COUNT         2778 a         1708 c         2107 g         2460 t
ORIGIN      
        1 caggctggaa acaagaaaac ggtatgtggt acttctacaa tactgatggt tcaatggcga
       61 caggttggct acaaaacaac ggttcatggt actacctcaa cagcaatggc gctatggcta
      121 caggttggct ccaatacaat ggttcatggt attacctaaa cgctaacggc gctatggcaa
      181 caggttgggc taaagtcaac ggttcatggt attacctcaa cgctaatggt gctatggcga
      241 caggatggct ccaatacaac gattcatggt attacctcaa cagcaatggc gctatggcga
      301 caggatggct ccaatacaac gattcatggt attacctcaa cagcaatggc gctatggcga
      361 caggatggct ccaatacaat ggctcatggt actacctcaa cgctaatggt gatatggcga
      421 caggatggct ccaatacaac ggttcatggt attacctcaa cgctaatggt gatatggcaa
      481 caggttgggc taaagtcaac ggttcatggt actatctcaa cgctaacggt tcaatggcaa
      541 caggttgggt gaaagatgga gatatctggt actatcttga agcatcaggt gctatgaaag
      601 caagccaatg gttcaaagta tcagataaat ggtactatgt caatggctta ggtgcccttg
      661 cagtcaacac aactgtagac ggatatactg tcaatgaaaa cggtgaatgg gtttaagccg
      721 attaaattaa atcatgttaa gaacatttga cattttaatt ttgaaacaaa gataaggttc
      781 gattgaatag atttatgttc gtattcttta ggtacctgtc ttatgatttc aggaaatatc
      841 attaaaaaaa cgactccttt tctctaattt gaaaaataga ttagagaaaa tgggttgttt
      901 tatttattat agttatttga atgaagataa gaagaaggta tactcacatc attcacatga
      961 tctgtatatt gactataagt tttaaaaaac aatttttaag ctcttccttg tcttctctaa
     1021 ccaagcgtgt tataatgaat actgctcaag cgaccttcaa tcgtgaagca cacacgacct
     1081 tcaatcgtga ataaacgaat agatgggaga cttaccatga gtgataactc taaaacacgt
     1141 gttgtcgtgg ggatgagtgg tggtgttgat tcgtcggtga cggctctttt gctcaaggag
     1201 cagggctacg atgtgatcgg tatcttcatg aagaactggg atgacacaga tgaaaacggc
     1261 gtctgtacgg cgaccgaaga ttacaaggat gtggttgcgg tggcagacca gattggcatt
     1321 ccctactact ctgtcaattt tgaaaaagag tactgggacc gcgtttttga gtatttccta
     1381 gcggaatacc gtgcgggacg cacgccaaat ccggacgtta tgtgcaacaa ggaaatcaag
     1441 ttcaaggcct ttttggacta tgctatgacc ttgggggcag actatgtagc gactgggcat
     1501 tatgctcgag tggtgcgtga tgaggatggt accgttcaca tgcttcgtgg cgtggacaat
     1561 ggcaaggatc agacctattt cctcagccaa ctttcgcaag aacaacttca aaaaacgatg
     1621 ttcccactag gacatttgga aaagcctgaa gttcgaaaac tagcagaaga agcaggtctt
     1681 tcgactgcta agaagaaaga ctcgacaggg atttgcttta tcggagaaaa gaactttaaa
     1741 aactttctca gcaactacct gccagctcag cctggtcgta tgatgactgt ggatggtcgc
     1801 gatatgggcg agcatgcagg tcttatgtac tatacaatcg gtcagcgtgg cggactcggt
     1861 atcggtgggc aacacggtgg tgacaatgcc ccttggttcg ttgtcggaaa agatctaagc
     1921 aagaatattc tctatgtagg acaaggattc taccatgact cgctcatgtc aactagccta
     1981 gaagccagtc aagtccactt tactcgtgaa atgccagaag agtttacgct agaatgtacg
     2041 gctaaattcc gttaccgtca gcctgactct aaggtgaccg tccatgtcaa aggagacaag
     2101 gcagaagtta tttttgcaga accacaacgc gcgattacac caggacaggc agttgtcttt
     2161 tacgatggcg aagagtgtct aggtggcggt ttgattgaca atgcttaccg cgatggacaa
     2221 gtttgtcagt acatttagat tgacaaattt tctcaatttg ctacaataat aacagcaata
     2281 gaaatgatgg tcaaagctca tggatgttgc aggctttttt gtcctgcact tctttgtagt
     2341 tttgactgtt tttgtgtcgt ttaagggaaa ggacaagaat gactcaacaa gactttcgga
     2401 caaaagtaga caatacggtt tttggtgttc gggctacagc cttgattgtc caaaatcaca
     2461 agcttctagt taccaaagac aagggcaagt attacactat tggaggtgcg attcaagtca
     2521 atgaaagcac ggaagacgcg gtagtccgtg aagtgaagga agaactgggt gtcaaaactc
     2581 aagctgggca gctagctttt gtggttgaaa atcgttttga acaagacggc gtttcctatc
     2641 acaatatcga gtttcattat ctggtggatt tgcttgaaga tgccccgttg accatgcagg
     2701 aagatgagaa aaggcagccc tgtgagtgga ttgacttgga taagcttgag gatatccagc
     2761 tagttccagc ctttttaaaa acggccctac cagattggga aggccaacta agacacattc
     2821 atcttgaaga ataggagaga aacatgactt atcattttac tgaagaatac gatattattg
     2881 taattggtgc gggacacgct ggggttgagg cttccttagc tgctagccgt atgggctgta
     2941 aggtcctgct tgcgactatt aacattgaaa tgctggcttt catgccttgt aatccctcta
     3001 tcggtggttc tgctaagggg attgtcgtac gtgaagtcga tgccctcggt ggcgagatgg
     3061 ccaagaccat tgacaagact tacatccaga tgaagatgct caacacaggg aaggggccag
     3121 ctgtccgtgc tcttcgtgcg caggctgaca aggaacttta ctctaaggag atgcgcaaga
     3181 cagttgaaaa tcaagaaaat ctgacccttc gtcaaaccat gattgatgag attttggtgg
     3241 aagatggcaa ggttgtcggt gtgcgtacag ccacccatca agaatatgct gctaaggctg
     3301 ttattgtgac gacagggact gctctccgtg gggaaattat catcggagac ctcaagtact
     3361 catcaggtcc taaccacagc ttggcttcta ttaacctagc tgacaatctc aaggaactgg
     3421 gcctcgaaat cggtcgtttc aagacaggaa cccctccacg tgtcaaggct tcttctatca
     3481 attacgatgt gacagaaatc caaccaggag atgaagcgcc taatcacttc tcatacactt
     3541 cacgtgatga ggattatgtc aaggaccaag tgccatgctg gttgacctac accaatggta
     3601 ccagtcatga gattatccaa aacaacctcc accgtgcgcc tatgtttaca ggtgtggtca
     3661 agggagtggg gcctcgttac tgtccgtcga ttgaagacaa gattgtgcgc tttgcggaca
     3721 aggaacgcca ccaactcttc cttgagccag aaggacgtaa tacagaggaa gtctatgtgc
     3781 aaggcctctc aaccagtcta cctgaggatg tccagcgtga cttggttcat tccattaaag
     3841 gtttggaaaa tgcagagatg atgcgaacag gttatgccat tgagtacgac atggtcttgc
     3901 ctcatcagtt gcgtgcgact ttggaaacca agaaaatctc aggtctcttc actgctggtc
     3961 agacaaatgg aacatcaggt tatgaagaag ctgctggcca agggattatc gcgggtatca
     4021 atgcggcttt gaaaatccaa ggcaagcctg aattgattct aaaacgaagt gacggttata
     4081 tcggggtgat gatcgacgac ttggtgacca agggaaccat tgaaccttac cgtctcttga
     4141 ccagtcgtgc tgaatatcgt ctcattcttc gccatgacaa tgctgatatg cgcttgactg
     4201 agatgggacg cgagattggc cttgtggacg atgaacgctg ggctcgtttt gaaatcaaga
     4261 aaaatcaatt tgataatgag atgaagcgcc tagacagtat caaactcaag ccagtcaagg
     4321 aaaccaatgc taaggttgag gaaatgggct tcaagccgtt gacagatgcg gtgacagcca
     4381 aggaattcct tcgccgtcca gaagtttctt accaagatgt ggtggccttc atcggaccag
     4441 ctgcagagga attagatgac aagattatcg aattgattga aacagaaatc aagtacgaag
     4501 gttacatctc aaaagccatg gatcaggttg ctaagatgaa gcgcatggaa gaaaaacgta
     4561 ttccagccaa tatcgactgg gatgacattg attctatcgc aaccgaagcc cgtcagaagt
     4621 tcaaactcat caatccagaa accatcggcc aagccagccg tatttcggga gtaaacccag
     4681 cagatatttc tattttgatg gtgtatctgg aaggtaaaaa tcgtagtatt tctaaaactc
     4741 ttcaaaaatc aaaatgatac gtcgtaggct tcttacgaat gagttcaaag cttggctttg
     4801 attcatctcc aacctcccat agttccccga actatgggag ctaactcaag ttatgcattt
     4861 tcctagcctt ctggtctgat tttcattgag ttttaatcta aaaagaaagc atagagaaaa
     4921 acagctccga agacggggct gttttgttga tttgtactca atgaaaatca aagagcaaac
     4981 taggaagcta gccgtaggtt gctcaaagca ctgctttgag gttgtagata gaactgacga
     5041 agtcagctca aaacacagtt ttgaggttgt ggatagaact gacgaagtca gtaaccatat
     5101 atacggcaag gcgaagctga cgtggtttga agagtattat tcttcatctg gtgtgaggat
     5161 catcgggatg atgatcggtt cacgttcggt attttcatag aggaaggggc gaatagcgtt
     5221 gacaatggca ccattgacag attgcacgct agcatcctta tttttcagtg cgatacgaat
     5281 ggcattgaag aggatacgct ggctttggcg aatcaagtct ccagactctc tcatgtagac
     5341 aaagcctcgg ctgaggatat ctgggccaga cagaatcatc tgcgatttga agtcaacagt
     5401 tgcgactgct agaacgacac cgtcttcaga tagatcgcga cgatctttga ggacagctgc
     5461 gccaatttca ccgatacgat ttccatcgac atagatatct tgggcgttga aatgacctgc
     5521 gatacgagct gagtcagcag taagggcaag cacatcgcca ttgctcatga taaagatatt
     5581 gtccttttca acaccagtat ccactgctag tccagcgtgg actttttgca tgcggtattc
     5641 accgtggaca ggcatgaagt attttggctt aatcaagcgg agcatgagtt tttgctcttg
     5701 ctggccaccg tgtccagatg tatggatatt gttcacttta ccgtggataa cttcgacacc
     5761 agcttcagaa atgatgttaa tcagcttgtt gacgctagta gtgtttccag ggatgggact
     5821 agaagagaag ataacggtat cacctggttg taattgtact tgacggtggg ttccgttggc
     5881 gatacgagag agggctgcca taggctcacc ctgactacct gtacagagga taagaacttc
     5941 tcctgcagga taatctttga tttcatttgg ctcgataaag gttcccttag gagctttgat
     6001 gtagccaaga tcgattccgt tgacaatggc cttttccata gaacgaccaa agaccgcaat
     6061 cttgcgtcca gtcttaacag cagcttctgt tgcctgctgg agacggaaga tatttgaggc
     6121 aaaggatgca aagatgatac gtccttcaat accttggata atcttcataa tggactgacc
     6181 aacgactttt tcagagttgg taaaggttgg tacttccgca tttgtcgagt cagacaggag
     6241 acagagcacg ccttcttcac caagcgcagc catacgatgc aagtccgcag gttctccaac
     6301 tggagtaaag tcgaacttaa agtcacccgt acagacgatt ttcccttgag gagtatgaat
     6361 gacaatcccc aaaggctctg gaatagagtg agtcgttcta aagaaagttg ccttgagatt
     6421 tttaaaggtc aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc gcaagaggcc
     6481 gtgttcttcg agtttcccac ggatcaaagc caaggcaagc ggtccagcat aaatagggac
     6541 atttgcttgc ttgagtagga acggaatccc accaatgtgg tcctcgtgtc cgtgtgtgat
     6601 taaaacagcc ttgacgcggt cgatattgtc tacgatgtaa gagtagtcag gaatgacata
     6661 gtcgatacca agcaagtcat cttctgggaa tttaatccca gcatcgacga tgataatctc
     6721 gtcttggtat tcaattccgt aagtgttttt cccgatttct cctagaccac cgatggcaaa
     6781 aacgccgact tcttcaggtt taagagtgta ggtcatatta gaactccgta atttcgaagg
     6841 cgccagtttc tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata tattcgatat
     6901 tgtactctgg gcgattttct tcgacaagtt ggcgagcagt gatacggccc tcaagttctg
     6961 agctggcatc gatgtctagg taaagcgcgc gtgttgtttc acggcgtggg ctacgttctt
     7021 ttgtttcttg ataaaaaact ttgtaaatca tatagttcct ttctatttac aggtcagctt
     7081 attccaaact tttagcagat atttgcttga tttcattcca ttttgtgtct agattgacct
     7141 tgattcgtta caattatttc aattatacca taaaatgaaa aattagtaaa agacggaaat
     7201 ggagaaagta gggatggtaa gaaggagcaa aaagacaggt aggatttggt cggagagtgc
     7261 ataggtgtta taattaaagg gggaatctat ggagatagta gatttaagga agaatacagt
     7321 tttagtttca ttaatcgttg gattagatgg ttgggataga atgatatctt tgaaaaaaga
     7381 aaaagctctt gagaaatctc gagagcaaac aaaaaggctg agacaaaatt aagggatctt
     7441 tctgagcaag ctcaaggggc agcaccatta cctgaagtga ttgaatcaca acctttgaaa
     7501 gacttgtcac caagtcagac caaatctcaa cctttactct attttatcat ctatgaggct
     7561 aagaagtcaa tctataagta taacgatgta gaaatagcaa gatgtagtgg agtgcttact
     7621 aaaaggtaaa gacaagccct taatttaaga gtaagcaaaa agagaggacg tatctgctca
     7681 agggttcttt acagcccgaa gctgaaggta gcacctcacc cgtacttgaa acaagtacct
     7741 ttgaacgctc tgttactagt cgccctacgt tatcctccca atatttatat tttactataa
     7801 cttactgagg gaatcaactt taaaagcatc aaaaatccct tgaccgaagt caagagccaa
     7861 tgttaaaatg gagaaaaata ttataaggag aattattaga tgaatgaaat cgttgagaca
     7921 acattgttat taaatctatt ctattatcag aatgaaacat attcaagaaa cgaagttttc
     7981 attgaatcca aaaagagaaa agctatttca attttagatg aatatgctga tgaactaaaa
     8041 gaaattgatg aagatttata taatgaatat aaagaaacaa ttacttttct tgaaggtatt
     8101 tcagaagaag aatatcaaaa tattaaaaat gaaattatcg aaagtgtaaa ggaatttata
     8161 aagaatgaga gatgatatga gaccgacatt taaacaagta agagactact ttattaataa
     8221 agaggcgaaa cctcccatca ctaatgcata tatgaaaaca aaatttggac aaacaaaagg
     8281 aggttatatt gatttcgcta aggtttgttc ttcacaagga gaatatattt caaaagatga
     8341 acagcattat aaaaattatg aagttcttaa aaactgtata gagaaaaatt tatttgaaga
     8401 atatgaacta tcttatctgc ggaaaatgag tgatatctcg attttagact taaacttaga
     8461 tgataaatgt gaaccaaatc aaaaatggca tctatatgtt tcattgtttg ctcagacaat
     8521 aattgaaatc aaaaatgaag gtaaaactgc tgaagacttg tggacaacag agtttcgtaa
     8581 atatctgagt ttacaactaa aattatggat ggctgaagtt gtggggctag atgtgcaaga
     8641 aattggtgat gctattaaga atagtgcagg taagagcaaa gtaaacaact tgattaagga
     8701 aatatcctgg gatgctattt ttgagatagt atataaagaa tcaatttaaa aatattatag
     8761 gagatgcaat ggaccttatt gaaagactct tagaagaacg taacacaaaa cttcatgggg
     8821 gaatctacga tataacccaa aaacgttttg cctatcattc caataaaata gaaggtagta
     8881 gcctgactga aaatcaggtt agttttattt atgatacaaa aatcatcgca aatatcgggg
     8941 aaaggggaat cagaattgat gatgtgattg aaatggcaaa tcatttcaaa tgttttgact
     9001 acattctgga tactgtgaat gaaccactga cagaagctta tattaaaaaa att
//
LOCUS       DAVDFK010000056         8541 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.56, whole genome shotgun sequence.
ACCESSION   DAVDFK010000056 DAVDFK010000000
VERSION     DAVDFK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.56"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..773)
                     /locus_tag="VUR04_001848"
     CDS             complement(<1..773)
                     /locus_tag="VUR04_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341695.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTVVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKDYEEAKKKAKEAQKKYDEEQKKTEEKAKKEKEAAKKVDDASLAV
                     QKAHVEYRKVLFSRNSYKYKSDYDKKLAEAQAKIDEANKKLTAANNEFQTVRAVVVPE
                     PNALAETKKKAEEAKAEEVVAKKKSDEAAQEVEVAKKEVEAKELEIEKLQDEISTLEQ
                     EVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAEL"
     gene            complement(1323..1562)
                     /locus_tag="VUR04_001849"
     CDS             complement(1323..1562)
                     /locus_tag="VUR04_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341696.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            complement(2694..3422)
                     /locus_tag="VUR04_001850"
     CDS             complement(2694..3422)
                     /locus_tag="VUR04_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341697.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKESQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            complement(3419..3772)
                     /locus_tag="VUR04_001851"
     CDS             complement(3419..3772)
                     /locus_tag="VUR04_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET5341698.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            complement(3918..5270)
                     /locus_tag="VUR04_001852"
     CDS             complement(3918..5270)
                     /locus_tag="VUR04_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HET5341699.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQTLQNELIQLQQQGDSSSLSDTTSDDDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILASNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKVDVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVILQKDMPVEVQIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(5267..5734)
                     /locus_tag="VUR04_001853"
     CDS             complement(5267..5734)
                     /locus_tag="VUR04_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5341700.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(5727..7946)
                     /locus_tag="VUR04_001854"
                     /pseudo
     CDS             complement(5727..7946)
                     /locus_tag="VUR04_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
BASE COUNT         2764 a         1666 c         1144 g         2967 t
ORIGIN      
        1 tttagctcag cttctccttt ttttaattta gcttctataa cttctgtgcc atcatcagga
       61 tccgcaccag caagaagttt tttcaaatta tctacttgat gttgagcagt agcaacttct
      121 tgttccaaag tagaaatttc atcttgaagt ttttcaattt caagttcctt agcctctact
      181 tctttcttcg ctacttctac ctcttgagct gcctcatcag attttttctt agctactact
      241 tcttctgctt tagcctcttc tgcttttttc ttagtctcag ccaacgcatt tggttcagga
      301 actacaactg ctcttacagt ttgaaactca ttattagctg cggttagttt tttattcgct
      361 tcatctattt ttgcttgcgc ctctgctaat tttttatcat aatcactctt atatttgtag
      421 ctattacgag aaaatagaac ttttctatat tctacatgtg ctttttgtac cgctaaacta
      481 gcatcgtcta ctttcttagc agcttctttc tcttttttcg ctttctcttc agttttcttc
      541 tgttcctcat catatttttt ctgagcttct tttgctttct ttttagcttc ttcgtaatct
      601 ttcttagcag cttcagattt tttcactgct gcatcatagt ctttctcagc tttagactga
      661 ctagctacgg gagcttcttc tgctcttaca acagtaggct gagacgtaac aaaaccagcc
      721 cctaagatag cgacgctggc taggcttgtt aaaatcattt ttttcttatt catctaaatt
      781 tacctctttt ctgataatca tttttagact atacttatat taagtatact ccccccgtaa
      841 atatttgtca aatgttttat attacatttt tattacaaat ttctatatca taagcttcta
      901 ctccaaaaag ataaagacac tacttttgcc cttttcgatt ctctttttaa acatagcatc
      961 atcttccttc attcctataa aaacatttcc gatgagagag cttgtttttt aatttcgtta
     1021 aacaacaaaa aacgcaagct taaggctgcg gacaatcttt atagccattt catttctttc
     1081 acatctgttt tacgaacttt agcatatttc ttagcgcttg taaaatgtag agtaactggt
     1141 ttaaatactc cgcttttgtc tcttcgtaaa cctaaaactg cggatctttt atttttatcc
     1201 tcaaaaaata tgacgtccaa tttcatagta tttttagata aatccttagc tacgatgcaa
     1261 caacttgcta gcttagatat agaagatatc gccgataaac tcacataaag atatcctttc
     1321 gattacatca ttgtacatag gatatttcta aaatcttcta aaataaaaac accatcttga
     1381 atagcaggtt ttgtttgact agcataatct cgtgtgattt tgtgtaagtc aaataaatga
     1441 tgtaaatcag tcaagcaaaa attcactttg aaaatctcta aatacttata attcgttgat
     1501 acttgacatg tttttccatt gaatctttct tgataatcca aaatacaatc aagtaatttc
     1561 aacgacaaac tccatatttt ctcaaaataa aaagcacggg gcagttacca ctactgccca
     1621 aagtggttga ttagagtcgg cttctctaac tccctatgtt gtgcttatta ggcttatcgc
     1681 aagggaacag tttttagatc tgccaagcca catagtgtgc ttactactat gtgtccatgt
     1741 caccatgaat taccgaacgg tttaacgaga aagtatagta gattgaaaca agatgtgaac
     1801 aaatcgatta ggaaagtcaa attaatttct agaaatattt taacagtcat aacggactat
     1861 tccagattca atctactata ttacttttag gtttatccca actcaattat gacatttttt
     1921 tcaaaagtca atatatctca ctcttttcaa cgacaagaaa gaggctgata atcgaccaac
     1981 ctctgttttt agatacagtt caagtccaaa ctattcttta tagaaaagtc cgataaattc
     2041 gagcaatagt taacatactt acaaatataa ctcccaaaat agataacact attttcacaa
     2101 aactcagttc cgaacctatg acatatatat gaaaaagagg ggctagtcct acacatatat
     2161 acaataagta gccaacaagt tttatctcac caattcctgc aaaaaaatgt ttcatgtgac
     2221 gattctccat ttactccatt aaatcagttt tattttagac tatcataaaa caatcacctc
     2281 ttcaataaaa accatttgcg aaatactatt ctgaagcatt gatagctcag atttctcaga
     2341 atagagctgt cctaactatc gagcagctca aatacatata tatgagcaat tctaagccta
     2401 gaattgctat aaaataaatg tttccaggct attctaagtc tttgactgct taaaatttta
     2461 cgttctgaag gattctaaag ctagaacagc tcaaaatcac gagaactaag gtattcgaaa
     2521 cttcagagta atacaatccc cataggaatt ctccattctt attaagcatg attaaaatgt
     2581 aatcctaaca agtgatcctc gactgtgttt gtagcactta gttacctaga taagactatt
     2641 tccctttatc atatctgatt ttaagccgtt ctaagattta acctatgttt ctattacttg
     2701 ctatttttaa ataattcgta ttcctttgct ttgataaatg gaactgaaaa attagaaaaa
     2761 agaagtaaaa ccgaaaacaa atagcctgct ttttgaatca ctaaaagata tcctaaaaat
     2821 aagtaagcta taacatccaa tgcgaaaaga aaaaatattc tcctcttcat taaagtactt
     2881 gtgtcaaata atctgatgaa taaaaatttt atcgtagtat ctacacaaat ttttatcaaa
     2941 aagataagag ccaatacacg attatcaact gtaccgtaaa gaatagatgg aaatatagtt
     3001 aatataaaac tagaaatctc taaatatttt atccaaggag attgagactc cttgcttcta
     3061 aactgactaa ttttcttata ttcgttagtc aatttagtag caaaatcttc cccaattaaa
     3121 tgaaagattg ctaactctag gataaaaaca cttattaata cggtataagt caaaaaactt
     3181 tctgggaaaa acttattgat taaaatgggg aaactcatta acagaatcga atttatggct
     3241 agacagatag atactatttt atttttcaca gaatatagag gtagtgatac tattgagtag
     3301 ataaaagcta aaaaaataag caaaaaatac tccgtgtcat ttataatcgc cctgaatgat
     3361 aaaaatatat acatccaaca tacgataata tgtatttttc gaatcttatc tacattattc
     3421 atcttactgt cgcagatatg aatccatccc aaggataagg gttcccgcta atatcacaac
     3481 ctctattaag agcaccatat ccaatacagt aagctatttt tcctgctgct gtagccaata
     3541 cacctgctgc tgcaccaata agccagcctc caagacctcc aaacttaata tagtttatta
     3601 gttttttagt taaaactgca gatccagcta atgctataaa agttcctggg ctcatagcta
     3661 aagctgcaca aattccttga caatcactct tgcttaaata agccccccca tcaagataca
     3721 tcatctcttc ttgctcaaga gcaacataat tatttggtaa tacgagttcc atttattttc
     3781 tcctttttta ttaagcatgg ttaggatagt ttcctaacaa gtgagcatcg actttgttta
     3841 tagcacttag ttacctagat aagatatctt ccctttatct tactttattt tataggtgac
     3901 ttaatgttta aaaccaatta ttgcttgaaa cttaacattt ccaaaatcca atcaagatag
     3961 gtttctttat catagacaat ctgcacttca actggcatat ccttttggag tatgaccgtc
     4021 tcgcttccat gttttagagt taaggtttct aattctatca tgactttata gaggctaata
     4081 ttcccctctt tcgtttcttg ggaaattgtt cctgaatcaa tctgtctgac ttgtcccttt
     4141 agtgttccat atttttgact atttacacca gtaatagcaa catcaacttt tgctcctttt
     4201 gagacacgag aaatatcact cgcaagtaca aaagcctcta catagtaacc tttttctttc
     4261 cctgaaactt ctgctatcgt ttgcccctgc tgaatagaca ttccttgttt caaaggtacc
     4321 agataatgca gagtaccttc atttgacgct aatatactat gagctttatc ttgacctgtt
     4381 gccactccaa gattagcctc aagctctgta atacttttat tgttgtttga acgagcagta
     4441 cctaactcac taattaattg agcataaata ttataagcct gagaagttgg atcattatag
     4501 gtacggttca tatccttaat attgctttgt tgactatcaa tctcgctatt cttagaagta
     4561 atatttgttt ttaatgcttc gatttttgtt gttatttctg atatcttagt ttctaactta
     4621 gctttatcat catctgatgt cgtatctgat aaggaggatg agtctccttg ctgttgaagt
     4681 tgaatcaatt cattttgtag agtttgcaag tcggcatcta actgatttct ttcagctgtt
     4741 attttattca acttcgtata ttcatcctga atctttgaat actgggtacc attattataa
     4801 ttttccgagt ttaactgaga cagatagtat tcaactttcc cataatattc ctgttcttca
     4861 ccagaattag ataaatgatt gtatttctca tttaatgatt gttcaaattt ttgaaagata
     4921 gcttcttttg cacgtaactt ctccaattgt ttatttaaag agctcgcttg taaaccttct
     4981 tgtccacttg ataacgaaat aatgacatct ccagcattta ccatatctcc ttctgactta
     5041 tgtaaagtaa ctaccttccc tgaaccaatt gctgatagga actctgtacc tgttataact
     5101 gaatttccat tcgcttttac aatatagttt ttgggtatat aagctgcgcc aaccaatgca
     5161 ccgcttaaga taatagcagt tgaaataatg agaataaacg caaaagctgg tggtctctta
     5221 tcaaagaaaa tacgagaata acgtaattct gatttattat ataatttcat aggcttacaa
     5281 ttggtctaaa aatatctact accatttttt caggagaaga attaacataa actgtataga
     5341 caatcccatc cgtttgaata tcattttcat agacatatag atccaattta gaatacgcat
     5401 actgtagata ctctggactg tcttcaaaac gaacatataa acaatatgga acagagatag
     5461 aatcctgtac atcataaatg ttactgtact gttgagcatt atgagcttga atataaaact
     5521 caaaatcagt cgttattaat ccatcatcat gaatagtagt accacaactt tttacaatta
     5581 atggaccaaa aatttgtgct tttaacaact gcaaatgttg atgaaattta ttaatttcct
     5641 gatctacatc ttctactttt gtatcatgta actttttaca gataactgac tttagtacca
     5701 gttttttatt atcttttacc tctaacttag ccataagtaa cctcctctgt atctaacaca
     5761 gcctgtgact gaatttgttg attcacttga acgctctgca aaccaaccat tctagcatac
     5821 tttccatttt tcgccattag ttcttcatga gtcccatatt ccacaatagt cccattttct
     5881 aaaaagcata tcttatcaca tcgaagaatt gtagacagcc tgtgggctac tacaattgtt
     5941 gtcttatcca ttattttatt aaagattaaa tcctgaataa tctgttcact aaatgaatct
     6001 aagttagagg ttgcctcatc aaatatatac aaatcagctt tactcagtag tgctcttgca
     6061 atagccaatc gttgtttctc tccacccgag aaattttgac cgtcttcttc tacaaaggag
     6121 ccataacgat tttgaagacg ttgaatcgta tcatgaatac caacaatacg acaaactctc
     6181 accatatcct catatgtaac agaaggatta ccaattttta gattatcaat aattgtccct
     6241 gtaaagagtt ctatggtctg aggaatgtag gaaattttct tacgtagttt accatagtca
     6301 agatctgata agtcattttc tcctatacga attttcccct cactcggatt tataaatctt
     6361 aataataaac gaactatcgt actttttcct gctccacttt caccaacaaa agctattttt
     6421 tctcattgtt taattcgcaa attaaagttc ttgataacag gtgggcgcga accataggca
     6481 aatgttacat ctttaaactc gatatcatca cataaggtga agtctctaat actataatcc
     6541 aaggcaatgt cttcacgatc tacttccatc aattcttgaa gtcgactaac cgcaacctgt
     6601 acctcttgaa aggttaactg caaaccaact aaattctgaa taggttctgt aaaatattga
     6661 cttaatgtct gaaaaaccaa gaggtcccca atagtcattt ttccatcaat gataaataag
     6721 gcgcccactc ccataaataa taacccaccc atggttgagg tcattgaaga tattgtagat
     6781 tgaatattct gcaaaacacc ctctttataa ccaatttcta aagtatgaac aaatttttct
     6841 tcaattttgt ttaaacgttg ttcctcgtca tgctgagact taatggtatc aatgttacga
     6901 atagattcaa ttaactgtga attaagaagt ccatttgctt ccatttgttc atgattaatt
     6961 tttttataag gctttttaaa acagtatata agaatgatgt taacaataac cataaaaact
     7021 aatatcagaa ataaagattg attaatagtc caaaggacaa ccgcactaat aactgacaag
     7081 gtgatatcca tgactaatga aatagagact gacgtaaaca cattctttat cgtcatcgca
     7141 tcttgaaatc tcgttaaaac atcaccaact ctacgacttc caaaaaaact ataaggaaga
     7201 tgaataatat ggtcataata tcccattaaa accggtatat caatttttcg agatagaaac
     7261 aaaagaacgt gctgacgaaa tgcagataga agagtctgta agaacgacac tattccaaat
     7321 actatcaaaa acatatacag actatttttt aaagcatatg gaatcacctc gtccatgata
     7381 acttttgaaa agagactcga taaaatacca atgatactta aaacaaagga agctaatatg
     7441 actgtactaa tcaatccttt ttgattaaaa attaacgttc caaataaatc aagaagtcct
     7501 tttcccttta gtttccctct ttcaaaatcc gaatttggaa ccataaaaag agtaatacct
     7561 tgataaattt ctcccagttc gtcacttgac atcttgcgta tgccactagc agggtctgct
     7621 acgtaaaatt tactattcct tttgatacta tgtaatacca caaaatgatt ttgacctaaa
     7681 tcattcttaa cttgaagaat cgcaggaaat gttaattttg gagtcaaatc ttccagtgct
     7741 actcgaacag cttttactgt aaaattcaac ttattcagac ctgaaacaat accactgaca
     7801 gtcgttccat acatgtctgt accaataatt tcccgaatct tcatgattga tagttccttt
     7861 ttgtaagata aaagaactgt tgaaacaact gccgcagcac aatctgactg gtcatgttgc
     7921 atcgtacaag gatatttttt taacatagaa atactcaatt ctttagaatt aatctaactt
     7981 ttctttgatg tcacccaaac ctcaatcact gcccagtagt tcttgaatta gtttattttc
     8041 aatcgtatca ttctttgttc ttgatatctt tccaagcatt gtagtacagc agatttttgt
     8101 ccaaggactg agcctccttt aacaactcaa gctcccttac attatatcag ccagccccat
     8161 ggaaagatta tggccagact aatcaatgat ataatacata ctagaataca aaatattttt
     8221 ttattcatac tttttctcct atctttattt tctacctaca tcatacctct tattaagctc
     8281 attttaaaat tacgttaact tttttcacag aaaggagaaa atcatgcgtt atgattatgg
     8341 atagcgcttt caaattttta aactcctatc ccatcctttt atctatataa taagtgaaaa
     8401 tataataact gtcaagtaac tgaagtgaat tttataaaaa aattacaagc caaatttgta
     8461 aagtttacac taagccgcta gagcaatcgt ctatcagaat gtccgtttat ttgtcaataa
     8521 tccgagaaaa tcttgcaacg c
//
LOCUS       DAVDFK010000057         7828 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.57, whole genome shotgun sequence.
ACCESSION   DAVDFK010000057 DAVDFK010000000
VERSION     DAVDFK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.57"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            407..6823
                     /locus_tag="VUR04_001855"
     CDS             407..6823
                     /locus_tag="VUR04_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET5341701.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHSAMETSQDFKEKKIAVIKEKEVVSKTPVIDTKTSNEENSNKS
                     QGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIFN
                     GSAIETIPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNFWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHFI
                     RGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISYY
                     LVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLFN
                     IHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGTD
                     LEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIKATKY
                     DSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
     gene            complement(7115..7461)
                     /locus_tag="VUR04_001856"
                     /pseudo
     CDS             complement(7115..7461)
                     /locus_tag="VUR04_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7645..>7828)
                     /locus_tag="VUR04_001857"
     CDS             complement(7645..>7828)
                     /locus_tag="VUR04_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341702.1"
                     /translation="FAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVMNQLQDV
                     IQGLEKEVIKSIVNRR"
BASE COUNT         2986 a         1116 c         1501 g         2225 t
ORIGIN      
        1 aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc ttcaaaccac
       61 gtcaacgtcg ccttgccgtg cgtatggtta ctgactacgt cagttctatc cacaacctca
      121 aaacagtgtt ttgagcaatc tgcggctagt ttcctagttt gctctttgat tttcattgag
      181 tactaatctt atttttaacg tgtgctaaaa aataaattaa tgcatgttaa tttttttgac
      241 ttaaattttt ttaaatgata tactgttttt atagagagat aacaattata tataaatgta
      301 ctactctatt tcctagataa tacttagtaa aactttttat aacaaaggct agcaaagtta
      361 aagtttatta tctattggaa gttatataaa tatgtaagga attaaaatga aaaaaagtac
      421 agtattgtca ttaaccacag ctgcagttat tttagcagcc tatgccccta atgaggtagt
      481 cttagcagac acatctagct ctgaagatgc tttaagcatc tctgataaag aaaaagtagt
      541 agtagataag gaaacagaaa ataaagagaa acataaagat atccatagtg ctatggaaac
      601 ttcacaggat tttaaagaga agaaaatagc agtcattaag gaaaaagaag ttgttagtaa
      661 aactcctgtg atagacacta aaactagcaa tgaagaaaat tccaataaat cccaaggaga
      721 tcatacggac tcatttgtga ataaaaacac agaaaatccc aaaaaagaag ataaagttgt
      781 ctatattgct gaatttaaag ataaagaatc tggagaaaaa gcaatcaagg aactatccag
      841 tcttaagaat acaaaagttt tatatactta tgatagaatt tttaacggta gtgccataga
      901 aacaattcca gataacttgg acaaaattaa acaaatagaa ggtatttcat cggttgaaag
      961 ggcacaaaaa gtccaaccca tgatgaatca tgccagaaag gaaattggag ttgaggaagc
     1021 tattgattac ctaaagtcta tcaatgctcc atttgggaaa aattttgatg gtagaggtat
     1081 ggtcatttca aatatcgata ctggaacaga ttataggcat aaggctatga gaatcgatga
     1141 tgatgctaaa gcctcaatga gatttaaaaa agaagactta aaaggaactg ataaaaattt
     1201 ctggttgagt gataaaatcc ctcatgcgtt caattattat aatggtggca aaatcactgt
     1261 agaaaaatat gatgatggaa gggattattt tgacccacat gggatgcata ttgcagggat
     1321 tcttgctgga aatgatactg aacaagatat caaaaacttt aacggcatag atggaattgc
     1381 gcctaatgca caaattttct cttataaaat gtattctgac gcaggatctg ggtttgcggg
     1441 tgatgaaaca atgtttcatg ctattgaaga ttctatcaaa cacaacgttg atgttgtttc
     1501 ggtatcatct ggttttacag gaacaggtct tgtaggtgag aaatattggc aagctattag
     1561 ggcattaaga aaagcaggca ttccaatggt tgtcgctacg ggtaactatg cgacttctgc
     1621 ttcaagttct tcatgggatt tagtagcaaa taatcatctg aaaatgaccg acactggaaa
     1681 tgtaacacga actgcagcac atgaagatgc gatagcggtc gcttctgcta aaaatcaaac
     1741 agttgagttt gataaggtta acattggagg acaaagtttt aaatacagaa atataggggc
     1801 ctttttcgat aagaataaaa tcacaacaaa tgaagatgga acaaaagctc ctagtaaatt
     1861 aaaatttgta tatataggca aggggcaaga ccaagatttg ataggtttgg atcttagggg
     1921 caaaattgca gtaatggata gaatttatac aaaggattta aaaaatgctt ttaaaaaagc
     1981 tatggataag ggtgcacgcg ccattatggt tgtaaatact gtaaattact acaatagaga
     2041 taattggaca gagcttccag ctatgggata tgaagcggat gaaggtacta aaagtcaagt
     2101 gttttcaatt tcaggagatg atggtgtaaa gctatggaac atgattaatc ctgataaaaa
     2161 aactgaagtc aaaagaaata ataaagaaga ttttaaagat aaattggagc aatactatcc
     2221 aattgatatg gaaagtttta attccaacaa accgaatgta ggtgacgaaa aagagattga
     2281 ctttaagttt gcacctgaca cagacaaaga actctataaa gaagatatca tcgttccagc
     2341 aggatccaca tcttgggggc caagaataga tttactttta aaacccgatg tttcagcacc
     2401 tggtaaaaat attaaatcca cgcttaatgt tattaatggc aaatcaactt atggctatat
     2461 gtccggaact agtatggcga ctccaatcgt agcagcttct actgttttga ttcgaccaaa
     2521 attgaaggaa atgcttgaaa aacccgtatt aaaaaatctt aaaggtgatg ataaaataga
     2581 ccttacaagt cttacaaaaa tagccctaca aaatactgca agacctatga tggatgcaac
     2641 ttcttggaaa gaaaaaagtc aatactttgc atcacctaga cagcaggggg cggggctaat
     2701 taatgtggcc aacgctttga gaaatgaagt tgtagcgact ttcaaaaaca cggattctaa
     2761 aggtttggta aattcatatg gttccatttc tcttaaagaa ataaaaggtg ataaaaaata
     2821 ctttacaatt aagcttcaca atacatccaa caggccttta acctttaaag tttcagcatc
     2881 agcggtaact acagattctc taactgacag actaaaactg gatgaaacat ataaagatga
     2941 aaaatctcca gatggtaagc aaattgttcc agaaattcat ccagaaaaag tcaaaggggc
     3001 aaatattaca tttgagcatg acactttcac tataggggca aattctagct ttgatttaaa
     3061 tgcggttata aatgttgggg aggctaaaaa taaaaataaa tttgtagaat catttattca
     3121 ttttgagtca gtagaagaaa tggaagcatt aagctccaat ggcaagaaaa ccgacttcca
     3181 accatcttta tcaatgcccc taatgggatt tgctgggaat tggaaccacg aaccaatcct
     3241 tgataaatgg gcttgggaag aaggatcaaa atcaaaaaca atggaaggtt atgatgatga
     3301 cggtaaacca aaaattccag gaaccttaaa taaggggatt ggtggagaac atggtataga
     3361 taaatttaat ccagcaggag ttatccaaaa tagaaaagat aaaaatagaa catctctaga
     3421 tcaagatcca gacttatttg cctttaacaa ccaaggtgtt catgcagaat ccactagtgg
     3481 ttctaagatt gctaacattt atcctttaga ttcaaatgga aatcctcaag atgctcaact
     3541 agaaagagga ctaactccat ctccacttgt tctaagaagt gcagaagaag gactaatttc
     3601 aattgtaaac accaacaaag aaggagaaaa ccaaaaagac cttaaagttg tatcaagaga
     3661 gcacttcata agaggaattc taaattctaa gggaaatgac gctaagggta tcaaatcatc
     3721 caaactaaaa gtttggggtg acttgaaatg ggatggactc atctataacc caagaggtag
     3781 agaagaaaat gccccagaaa gtaaggataa ccaagatcca gctactaaga tacgaggaca
     3841 atttgaaccg attgcggaag gtcaatattt ctataaattt aaatatagat taactaaaga
     3901 ttacccatgg caggtttcct atattcctgt aaaaattgat aacacagccc ctaagattgt
     3961 ttcggttgat ttttcaaatc ctgaaaaaat taagctaatc acaaaggata cttatcacaa
     4021 ggtaaaagat caatacaaga atgaaacttt atttgctaga gatcaaaaag aacatcctga
     4081 aaaatttgat gagattgcaa atgaggtgtg gtatgcagga gctgctcttg ttaatgaaga
     4141 tggagaggtt gagaaaaatc ttgaagtaac ttatgcaggt gagggtcaag gaagaaatag
     4201 gaagcttgat aaagatggga atactatcta tgaaattagc ggagcaggag atctaagagg
     4261 aaaaatcatc gaagtaatcg ccctagatgg agcaagcaac tttaccaaaa tccataggat
     4321 taaatttgct aatcaagctg atgaaaaagg gatgatttcc tattatctag tagatcctga
     4381 tcaggattca tctaaatacc aaaagcttgg cgaaattcct gaatctaaat ttaagaattt
     4441 aaaaaatgtt aaagatgata gcctaaacaa agagacagct gaggtggaaa ataacctttt
     4501 agtagataat cagtctatcg aaggaaaatc tctctttaat attcataaaa ctatttcaac
     4561 aattagagac tttgaaaata aagacctaaa gaaactcatt aaaaagaaat ataagcaaga
     4621 agacgacttt gtaaatggtg gaacaagaac agtagagcgt gattataaat acgatgataa
     4681 aggaaatata atagcctacg atgatgggac tgatctagaa tatgaaactg agaaacttga
     4741 cgaaatcaaa tcaaaaattt atggtgttct aagcccatct aaagatggac actttgaaat
     4801 tcttggaaag ataagcaatg tttctaaaaa tgccaaggta tattatggaa atagctataa
     4861 atcgatagaa atcaaagcga ctaagtatga ttcacattca aaaacgatga tatttgattt
     4921 atacgctaat attaatgata ttgtagatgg attagctttt gctggagata tgagattatt
     4981 tgttaaagat gacaatcaaa taaaagctga aactaagatt agaatgcctg aaaaaaataa
     5041 ggaaactaaa gcagaatatc cctatgtatc aagttatggg aatgtaatcg aattaggaga
     5101 aggagatctt tcaaagaaca aaccagacaa tttaactaaa atggaatctg gtaaaatcta
     5161 ttctgattca gaaaaacaac aatatctgtt aaaggataac atcattctaa gaaaaggcta
     5221 tgcactaaaa gtgactacct ataatcctgg aaaaacggat atgttagaag gaaatggagt
     5281 ctatagcaag gaagatatag caaaaataca aaaggccaat cctaatctaa gagtcctttc
     5341 agaaacaaca atttatgctg atagtagaaa tgttgaagat ggaagaagta cccaagctgt
     5401 attaatgtcg gctttggacg gctttaacat tataaggtat caagtgttta catttaaaat
     5461 gaacgataaa ggggaagcta tcgataaaga cggaaatctt gtgacagatt cttctaaact
     5521 tgtattattt ggtaaggatg ataaagaata cactggagag gataagtcca atgtagaagc
     5581 tataaaagaa gatggctcca tgttatttat tgataccaaa ccagtaaacc tttcaatgga
     5641 taagaactac tttaatccat ctaaatctaa taaaatttat gtacgaaatc cagaatttta
     5701 tttaagaggt aagatttctg ataagggtgg ttttaactgg gaattgagag ttaatgaatc
     5761 ggttgtagat aattatttaa tctacggaga tttacacatt gataacacta gagattttaa
     5821 tattaagctg aatgttaaag acggtgacat catggactgg ggaatgaaag actataaagc
     5881 aaacggattt ccagataagg taacagatat ggatggaaat gtttatcttc aaactggcta
     5941 tagcgatttg aatgctaaag cagttggagt ccactatcag tttttatatg ataatgttaa
     6001 acccgaagta aacattgatc ctaagggaaa tactagtatc gaatatgctg atggaaaatc
     6061 tgtagtcttt aacatcaatg ataaaagaaa taatggattc gatggtgaga ttcaagaaca
     6121 acatatttat gtaaatggaa aagaatatac atcatttgat gatattaaac aaataacaga
     6181 caagacacta aacattaaga ttgttgtaaa agattttgca agaaatacaa ccgtaaaaga
     6241 attcatttta aataaagata cgggagaggt aagtgaatta aaacctcata gggtaactgt
     6301 gaccattcaa aatggaaaag aaatgagttc aacgatagtg tcggaagaag attttatttt
     6361 acctgtttat aagggtgaat tagaaaaagg ataccaattt gatggttggg aaatttctgg
     6421 tttcgaaggt aaaaaagacg ctggctatgt tattaatcta tcaaaagata cctttataaa
     6481 acctgtattc aagaaaatag aggagaaaaa ggaggaagaa aataaaccta cttttgatgt
     6541 atcgaaaaag aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa gtcacagaaa
     6601 agaggattta caaagagaag atcattcaca aaaatctgat tcaactaagg atgttacagc
     6661 tacagttctt gataaaaaca atatcagtag taaatcaact actaacaatc ctaataagtt
     6721 gccaaaaact ggaacagcaa gcggagccca gacactatta gctgccggaa taatgtttat
     6781 agtaggaatt tttcttggat tgaagaaaaa aaatcaagat taagataaaa gctatagaaa
     6841 aaaatggttt atgtactgag attagatagt gaggtgatga catagttttg tgaaaacagc
     6901 catttataac tcaattattt agtttacttc actattgata ctatttggag ttattaatgg
     6961 acttagttta gataactaat gaattgattg aaagggttag tattgacaat attggtcata
     7021 ttgattagaa aatagagtct atcaaaattt aaaggctaat agaggtgatg agacaatttc
     7081 ggctctttgt caactgtagt gggttgaaga aaagctaagc tcgagaaagg acaaattttg
     7141 tcctttcttt tttgatattc agagcgatga aaatccgttt tttgaagttt tcaaagtttc
     7201 gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt attggtcgtt tccagtttgg
     7261 cattagaata gtgtagttga agggcattga caatcttctc tttatctttg aggaaggttt
     7321 tagaggatga acctgattca gattgtcctc aatgagtccg aaaaatttgt caggctcctt
     7381 attctgaaag tgaaaaagca agagttgata gagattatag tggtgtttca agtcttctga
     7441 atagctcaaa agtttatcta tagtagattg aaactagaat agtacacatc tgcttctaaa
     7501 acattgttag aaatcgattt gactgtccta atcgatttgt cctgttctta tttcatttca
     7561 ctataaattc atcagaaagt cgtgatttct attgaaatga ggactttctt tttatactca
     7621 tctgatttta aaaagcattc tagttcatct ccgattaacg atggacttta tcacctcctt
     7681 ctccagtcct tgtataacat cttggagttg attcatgaca tcttccaaag ttcgaaaggc
     7741 cttattctta aatccacgtt tacgaatctc tttccacact tgttcaatgg ggttcatctc
     7801 tggtgtgtat ggaggaataa atgcaaag
//
LOCUS       DAVDFK010000058         7779 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.58, whole genome shotgun sequence.
ACCESSION   DAVDFK010000058 DAVDFK010000000
VERSION     DAVDFK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.58"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..199
                     /locus_tag="VUR04_001858"
     CDS             <1..199
                     /locus_tag="VUR04_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341703.1"
                     /translation="KNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKK
                     RIFIALNIKKKGRILSFLELS"
     gene            complement(307..1812)
                     /gene="lytC"
                     /locus_tag="VUR04_001859"
     CDS             complement(307..1812)
                     /gene="lytC"
                     /locus_tag="VUR04_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET5341704.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(1850..2608)
                     /locus_tag="VUR04_001860"
     CDS             complement(1850..2608)
                     /locus_tag="VUR04_001860"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET5341705.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDFVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(2706..3383)
                     /locus_tag="VUR04_001861"
     CDS             complement(2706..3383)
                     /locus_tag="VUR04_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET5341706.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(3392..4336)
                     /locus_tag="VUR04_001862"
     CDS             complement(3392..4336)
                     /locus_tag="VUR04_001862"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET5341707.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            complement(4518..5030)
                     /locus_tag="VUR04_001863"
     CDS             complement(4518..5030)
                     /locus_tag="VUR04_001863"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET5341708.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(5117..5875)
                     /locus_tag="VUR04_001864"
     CDS             complement(5117..5875)
                     /locus_tag="VUR04_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5341709.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKCATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            complement(6376..7506)
                     /gene="ugpC"
                     /locus_tag="VUR04_001865"
     CDS             complement(6376..7506)
                     /gene="ugpC"
                     /locus_tag="VUR04_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET5341710.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
BASE COUNT         2310 a         1738 c         1297 g         2434 t
ORIGIN      
        1 aaagaacaaa gaaaaaatcg tcaacgctct tcaattacct tattccaacg caaaattaga
       61 agcgaccaat aatctcatca aacttatcaa acgaaacgcc tttggatttc ggaactttga
      121 aaacttcaaa aaaaggattt ttatcgctct gaacatcaaa aagaaaggac gaattttgtc
      181 ctttctcgag cttagctgac ttcaacccac tacagttgac aaagagctga atttactcga
      241 ggatgaacta tcataaaaca aagaaaaaga gggtgctact atcacatccc tctttcaaat
      301 catcgcttaa taccaaacgc tgacatctac gcgcccttgg attcctttca tgtattcaga
      361 agaggtatat tgccaacctt tttctcctga ataataaggg ttttcccatt ctaaagcatt
      421 cgtataggcc gctacccagt ttacatgttt taaaatatct gggtgtttta aacgcgtctg
      481 taataaacta cgatagctat agacatacac attttgataa cccgcctgct tcatcgtgtc
      541 catgtacttg ttgatgattt taacccaagt gtctgtatca cttggagctc tcttgctctt
      601 atttacatat tcccagttct caacatcata atagataggg taagacaggt tcatattgta
      661 tttctttata agttcaatgg tctgtttagc gtcattctca gcatcggtct cattttcagc
      721 ataggtatag agatagacac cataaggaat tcccagacgg tttaactcct taatgttatg
      781 cgccaattcc ttgtcttctt taccgctata acctagacga acaatgacac catccacctc
      841 gttctcatca ataacctttt tccaatcatt gatacgacca ttgtgctcac taatatcaat
      901 gattttctta gcatgttcgg ttcccacttg ttcttctcta ttattaaaga aatagcgttt
      961 accatctctg tgaacccagc cgacattcaa atctttcttt tctttgagct caccagaagc
     1021 cgcaaagata tagcgagcac catccataat cacttcgtca gtcgccatgg caccacttcc
     1081 agtcaaatag tagttgcctt gccactcatt ccgagccata tagccccact tcttgaaata
     1141 gtaccatttg ccacccactt tttgccactc ttggttagca taagttccat cggattttag
     1201 ataaaaataa gcagaataag ctggatcata gagccattca ttttgcatca tagctccttg
     1261 accattcaag aaataacttc cttgccattg gcttttagcc atgtaacccc acttcttgaa
     1321 gtagtaccac ttatttccaa tcaattgcca ttcttgatga gcataagccc catctgactt
     1381 gagataaaac caactcttgt aattactgtc atagatccac tcgttttggg ccatatatcc
     1441 acctgatttc aggtagtaat ttccatgcca ttcattctgc gagtaacgac catctgaatt
     1501 aatataaaac caagccttat agtagttgtc aaaaatccat tcactttgag ctttagaacc
     1561 atcatccttt acataataat ccccatccca gtgggcagca gcattagtct gtacttctgc
     1621 gctcgtttgc gttttattag aagactgatt ttgctctgaa ctacttgaag ctgtcgttgt
     1681 atcctgcgaa gtttttgcta cttcagtttc atttgcagcg acatgactag ttgccaagcc
     1741 tagtaaacag atacttgcta atccaatttt tattttcaat ctttcctctc ctataaaaaa
     1801 tgtaacagac atctgaatgc tgttccacct agcttttgct acttactgat tattttacaa
     1861 agtcaagcaa agccaagaag ctttcagctt caagtgacgc accacctaca agggcaccgt
     1921 caacgtctgg gcaagccatg tatgaagcaa cattttcagg tttaacagaa ccaccgtatt
     1981 gaacacgaac tttgtctgcg acttcttgac caaagtcagc agctacaacg tcacgaacaa
     2041 ctttacacat tttttgtgca tcgtcttgtg aagctgattt accagtaccg atagcccaga
     2101 ttggctcata agcgataact gaggcagcaa cttgttcagc agtcaatcca gccaatgcag
     2161 cagatacttg agcacctacg aattcagcag ctttaccagc ttcgtaagtt tcaagtgatt
     2221 caccacaaca gatgattgga agcataccgt tcgcaaagat tgcttttgct tttttgttga
     2281 tatcttcatc agtttcatgg aagtagtcac ggcgttctga gtgaccgata acaacgtagt
     2341 cagtaccgat ttctttcaaa acttgtgggc tagtttcacc agtgaaagca cctgcatttt
     2401 caaagtagca gttttgagca gcaactttaa ggtttgagcc ttttgcaaca gcaagaacag
     2461 ttgtcaaatc aagagctgga gcagcgatac ctgcttcaac aaaatctgat gaaggaagtt
     2521 ttgatgcaac tgcttcaacg aatgctttag cttcttctgg atttttgttc attttccagt
     2581 taccagcgat aaatggttta cgtgacattt cacatacctc ttttttcaat ttattttcta
     2641 tttattctat cacaattata cacagcttgc aaatcttact cggatttcaa gcctacttgc
     2701 atggattaat ccttccagag atccatggca tttctgaaat ctgcagatac ctgtgtcaac
     2761 tgaggattgc ttgcttctct ttctgctctc ttggcctcaa tttgagccac actcttgatt
     2821 ccttcatggc gccagtttct caaaatcgcc tgaatgtact tccagtttgg ttttccattc
     2881 aaaacagctt cacgaagagc ctccttaatc aagtcagcac tggttccatc ttcctttagt
     2941 gtcttggtca aatcctcaat ctcaaaaggc gtcaacaatc gtcccaactc ctgctggaag
     3001 gtttccacca aatccttgag ctggttttga ggtgttagct ggtctgaact tgaatgaact
     3061 gctccaaaca ggtcatccaa acgttccaag gccaaactag catcaaagag caattcaatt
     3121 tcgccattta attcgatagt acgatactgg agcagtcccc tttccgtcaa attagaaatg
     3181 gactggttga catccgaaat ttccttgcca atcctttcag caatctggct tggcgacatt
     3241 tcttctaagc ctgtcgtatt ttgcaaatag aaaaattgcc aaaccagaaa atcgtcgcta
     3301 gaaggaaaga gttccttaaa atgcaagagc agggcactag gtaaaaccaa ggtacctgat
     3361 ttaaaagcgt ctaaatatgt cataattcct cttataaata cctatatgca gatgcatcat
     3421 cttctatctt tctccagtca aaaggcgtct cctgatagac cgcatggttt acccaattac
     3481 tgaaaaagag ggctgcagat gaagaccaac aaagacaagg tacctgatta acatcatcat
     3541 ctttaaagta attttctgga atatgtgggt cgaaacctgc atcacgatct cgaaaatact
     3601 cttttgccaa ggtatcacgg tcatactcca aatgaccaaa actataaatt tctcgtaaat
     3661 cacgactggc caaaatagaa accccaacct gaggtccttc tgataaaatc tcgagattgg
     3721 tcttgtttaa gacctcttcc ttagaaatct ccgtgtgccg tgaatgaggg gatacatagc
     3781 tatcatcaaa gcctctaaat agaaggtgac cctcttttag ggtgtcctga ggataaatac
     3841 ctgatagctt actgtccatc tggtattttt ctacaccata gcgcagataa agcccagcct
     3901 gagcccccca acagatatga agggtcgaat agacatgagt cttagaccac tcaagcatct
     3961 gtctaaattc ctcccaatag tccacttcct caaatggtaa atgctcaact ggagcacccg
     4021 tgatgatcat cccatcaaaa tactcatcct tgacttcagg aaaagtttta tagaaggtct
     4081 ccatgtgctc tgaacgagtt gttttagaac ggtggctctc catatagaga aaatcaatat
     4141 ccagttgtag gggtgtatta gccaagtggc gcaacaactg ggtctctgtg accattttct
     4201 gtggcatgag atttaaaatt aaaatcttca aaggacggat atcttggtgg gcagcacgtt
     4261 gatcatccat gacaaagata ttctctgtcc gtaaaatctc aacagctggc aattttttat
     4321 caattcgaat cggcataacc ctctcctaac tgtactcttt caggaataat tgcatatgtt
     4381 tgaagacaaa tctcaaacac ttagtccttt tattatactg caagaagata tagttttcaa
     4441 ttatagtttt tctctaacta gttatagtct atttttatat cctagtgtag agaaaacagc
     4501 cctagggact gttttcatta ataatgcata agaactttgt agtcgtagtc accaattttt
     4561 tcacggccgt tcaattcatc caattcaaca aggaaggcac aacctgccat aacaccacca
     4621 agtttttcaa tcatctcgat agttgcctta acagttccac ctgtcgccaa aaggtcatct
     4681 acaataagaa cacgttgacc tggcttaatg gcatccgcgt gcatagtcaa ggtatcgaca
     4741 ccgtactctt tttcatagtc agcagaaata acttcgcgtg gcaatttacc tggcttacga
     4801 acaggcgcaa aaccaattcc caactcaaag gcaactggac aacccacgat aaatccacga
     4861 gcttcaggtc ccacgatcat gtcgactttc ttgtcagtag catactgaac gatttcacga
     4921 acagcgtagc tataagcatt tccatcagcc atcaaaggac taatatcacg gaaggtaatg
     4981 ccttcctttg gataattttc aattgttgca atgtaatctt ttaaattcat ctttttcttt
     5041 ctttcaaagt tttttactct ctattatagc atatttttta agaaagaaaa aaggaaaagt
     5101 taacttcaat aattatctaa cgttttgacg atttataact agccatcgca ataaagccca
     5161 atttctgttt attcttagca aacattttat acatagttaa aaactgcttt ctattctcct
     5221 ttttacaagc atttacacaa attttcaaag ttcctagcaa accttcgtca taaatcatac
     5281 ccgataattt cattaatgtc atttcaccag tcaatgcttt cacatcacaa taacctgatt
     5341 ctatcatcac ctgttcccaa ccatcttgag ttaaaggacc tacatttaca tgaattgctt
     5401 gtgataattc ctgtctgata gactctttag cttccttaag aagcacatca tgtgtcaaga
     5461 gaagacctcc aggttttaat acccttagat attccattac acattttttc ttagcttgat
     5521 cggcttgcat agtcagcata gcttcattta taacaatatc aaaactagca tcttgataag
     5581 gaagtttcat tgcatttgct ctttcaaaac tgattaaatg agcaacacct gccgttccag
     5641 cagatttttt agccacttct aaagcttgag catccatatc aacagcagtt atcttgcaac
     5701 caaaacgctg tgccaactca attgctgtag ttcccctatt acacgcaacc tctagtattc
     5761 tcttttcttt tgaaaatcct ccttctgcaa ttaaccaatc tgtggcacac tttccacctg
     5821 gacgtaagcg ttttttcccc aattttgcta aaaacttatg acctgcttct gacatttgaa
     5881 cacctctgtt ttttcttcat tataacacaa aatgatatta tctgacaatt ctaatctatt
     5941 atttgataaa ctagaatcaa aagcatacaa gtcaccataa ctatagcata aatttattat
     6001 tacctctcta gttcgaattc aattgctcac gtagtttacg catatagctt cacttgtaga
     6061 tggtacccac aaataatact caatggaaat caaagagcaa actaggaaac tagccgtaag
     6121 ctgctcaaag tacatctttg aggttgcaga taaaactgac gaaatcagta atcatacgta
     6181 cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaaa gagcatcaca
     6241 atatagatgc ataatatgac ttccctagca aaaaggagag aagcattttg tttctctccc
     6301 tagattaact gatatctctc cactacaatt gataaagaga tatcttttct tgtagtgctt
     6361 tgaattttat ttattttagt agattgtttt ttcagtttct acatcgaaga agtgtgcttt
     6421 gttcaagtca aatccaagct caactgttgc acctgtttgc aagtagtcac gagcatcaac
     6481 ttttgcaaca aactcgtctt taccaacttg gcagtaaagg tgagattctg aaccaagcag
     6541 ttctgataca gagatagtcg cttttacaac acagtctggg aatgtttcaa ggaaagcagg
     6601 ttctgcattc acgtcttctg gacggatacc aaagatcaat tcttttcctt cgtagccttt
     6661 ttcacgaaga actttcaatg ctccttctgg cactttcaaa cggaaaccgt cagaaacaat
     6721 ttcgctacca accaatttca cgttgatgaa attcatagct gggcttccga tgaatcctgc
     6781 aacaaatttg ttaactggat ttttgtaaac ttcttgagga gtaccgattt gttctacacg
     6841 tccgatagta cctgtaccag cagggttctt agtagctgac ataataacga tacggtctgc
     6901 aagtgtcatc gcttctgttt ggtcgtgagt tacatagata gttgtagctc cgatacgacg
     6961 gtgaatttta gcgatttcag cacgcattga tacacgaagt ttggcatcca agtttgacaa
     7021 aggttcgtcc atcaagaata ctttcgcatc acggacaatc gcacgcccca tggcaacacg
     7081 ttgacgttga ccacctgaaa ggtcagctgg tttacgttcc aagaattctt tcaatccaag
     7141 tatttcagct gcttcttgaa cacgtttgtt aatgtcttct ttgctgtatt tacgcaattt
     7201 caaaccgaaa gccatgttgt cataaacagt catgtgtggg taaagagcgt agttttggaa
     7261 taccatggcg atatcacggt cttttggagc tacgtcgttg acaaccacgc catcgataga
     7321 tgcagtacct tctgtaatgt cttcaagacc agcaatcata cggagtgtag ttgatttacc
     7381 acatcctgaa ggtcctacga aaacgataaa ttctttatct ttgatgttca agttgaaatc
     7441 ttcaactgaa tagtgttcgc tgtttggata ttttttgtaa atatttttaa gattcaattc
     7501 taccatgagg tgaactcctt ttgtcttttg ataattatat tatagatgaa aacgctttat
     7561 atttctatgg caagatgacc aaaaaaataa aaaagttctg tgcaacttgc acaaaacttt
     7621 agagaatatc ggagaatttg aagaagataa tctttattat tcttctatga caaaagcaga
     7681 aacaaggatc agttttccca tattttcgct gattctccac tacatttgac tggattctaa
     7741 ttttttagag aaatacaaaa gagctagctt tagcggctc
//
LOCUS       DAVDFK010000059         7719 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.59, whole genome shotgun sequence.
ACCESSION   DAVDFK010000059 DAVDFK010000000
VERSION     DAVDFK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7719
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.59"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(246..1006)
                     /locus_tag="VUR04_001866"
                     /pseudo
     CDS             complement(246..1006)
                     /locus_tag="VUR04_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            complement(1279..2121)
                     /locus_tag="VUR04_001867"
     CDS             complement(1279..2121)
                     /locus_tag="VUR04_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET5341711.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAHRAVLEALKAGYRHID
                     TAVIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(2235..3626)
                     /locus_tag="VUR04_001868"
     CDS             complement(2235..3626)
                     /locus_tag="VUR04_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET5341712.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3861..4238)
                     /locus_tag="VUR04_001869"
     CDS             complement(3861..4238)
                     /locus_tag="VUR04_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET5341713.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4403..5380
                     /locus_tag="VUR04_001870"
     CDS             4403..5380
                     /locus_tag="VUR04_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET5341714.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNTQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5377..6459
                     /locus_tag="VUR04_001871"
     CDS             5377..6459
                     /locus_tag="VUR04_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5341715.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRAHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6523..7574)
                     /locus_tag="VUR04_001872"
                     /pseudo
     CDS             complement(6523..7574)
                     /locus_tag="VUR04_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2323 a         1670 c         1317 g         2409 t
ORIGIN      
        1 tgtaaggagg tttctgccac tgacgcagtg aaatgttaat ttcttagaca ttgaatactc
       61 cttaataaaa aataattact tgcgacacga gtctgcctcg tcgatcatac gaggcaagac
      121 gagttagtac tgcgtctagc tcaggcactc tagtgctgag cgtggagcag cccgactgta
      181 aggaggtttc tgccactgat gcagtgaaat gttaatttct tagacattgt ttactccttt
      241 agtttttata tttctttttc aattaatttc tgctgaacaa accaatctaa caagggaaaa
      301 gttttttctg tatttgccca taaatgataa gaatctaaga tcgcttgtac actacctaaa
      361 ttttctacca acttatctac tgtcaaaaag ctgcgccagt attcataaaa aatacttgca
      421 tagttcttat cataagtcga agaaccaaaa tcattcaatg aatgccaact atacttcttc
      481 tgaaaaagtt ctacgagaga ttgattacaa attttttccg cttgaaattc ctcttctgtc
      541 aagaaatact tgcgactaat atattcaacc atcccctctt cgaaccagat ataagagtca
      601 taaccatcaa aatcatctaa aaaatgtccg accaatgagc taactcatgt cctacaatct
      661 gtaagaggaa attttcagat aaagaatgat agtgactttc tattgcttga gtttgctcag
      721 aacactcgta gtccatcaac tgatacaaat acaactcttt ccaaacagct aaatcaggcg
      781 tcataaccac tcgtctatta tttgtatagg ttggaacagc actttcccta ataatctgtg
      841 tagcagcatt aaaatctgac caaataacgg cttgcggtaa atcacagact gcaagttcat
      901 tctttaaaaa agattgataa tctttcaact tttcagtatt tcttactaca aaatcacgaa
      961 atgtagctag ttgactatcg tcttttacaa gataaaggtt gtccacggct ctcctttctt
     1021 tcacacaata gactgaataa gcaaaagaac cacatctgac aatcctaggt tgatttaacc
     1081 taggggcgtc agaaacgcgg ttccacccta atttattact tcattgtttt tgaaaatact
     1141 acagaaagcg ccagctcatt attttaccct acttggctcc cactgtccca agctcgcttg
     1201 aagaacgcca taagactttc tttcctgctg actattatat caaaaattag aataatgtac
     1261 aattcttttt atgattttct agaaatccac atcatcaact cgtggagcac ccgattgaac
     1321 agcaatcgtt tttaaggttt ctctctcctc atgactcagt tcaattccaa agcaatcaag
     1381 attagcttga atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc cttctgccaa
     1441 gctccaggcc aaggctatct gagcaacaga ctttccgtga tttgctgcta tttcttggac
     1501 ttgcttgcta tcaaacagtt ctccttgtcc aaaaggaccc caagcttcca ataaaattcc
     1561 cttttcacga cagtaagcta cgacttgatc ttgatacaca cctggcgcca agcgaacttg
     1621 attgaccgca ggaacgatag ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa
     1681 attgctaacg ccgatagcac ggattttccc ttcttgatag aggtcttcca tcgctctcca
     1741 aacttccgca ttgcgagttt tccatgcgtc attttctctg agcggttttg ggttcggcca
     1801 atgaatcaaa tacaaatcca aataatccaa gcccagtttt tctatagatt tttccaaagc
     1861 ttgacgagtt tgctcatagg tttgctgact attccaaagc ttggtagtta cgaacatttc
     1921 ttcacgtgga actccgctat ctttgattgc ttgaccaaca ctttcttcat tctgataaat
     1981 caccgccgta tcaatatgac gataaccagc cttcaaggct tctaacactg cacgatgggc
     2041 ttcttctcca tccttagcct taaaagttcc aaatcccaat actggaattt ctactccatt
     2101 atttaattga taggtattca tatgcttctc tttctatttt attcatcaat tatagcataa
     2161 aacatttttt aagtagtact atattctgta aaaaataagt ctgtcaaata tctaacagac
     2221 ctattttttc ttgcttattc atcacgacta tagtacaact catgagcttt taggcgagta
     2281 ttgagcatct ctggtatggt cacaaaggta taaccttgat ttttcaaata ctcaatgacc
     2341 cttggcaagg cattgactgt cggactgtga atatcatgca tcaaaacgat agagccgtta
     2401 gctacttgat gctgaatttc tgtcaaaata gatgcttcat ttttactctt ccagtccaga
     2461 ctatccacat cccacatgat aaagctcaaa tccaagctat tgcgaatatc atctgtaata
     2521 gcaccataag gtggacgcat gagtttagaa ctagaaccca gcactttagt tagcacatcc
     2581 tcagtatcag taatctgctt tttagcttca tcaagagaga gttgcgagag aatcggatgg
     2641 ctccaactat ggtttccaac aacatgacct tcagatttta tcctcttcac caagtcctca
     2701 ttcccagaaa catttttccc aagcacaaag aaagtcgctt taatatcata tttagctagg
     2761 gtctctaata cctgcggggt cgttgctgga tttggaccat catcaaaggt tagagcgaca
     2821 actttttgat atttcttatc aaagtaagat tggtacaagg ccgcatcttt ttcgagtaag
     2881 tacgaagatt ggataacatc aaagaaagca gatactggca aggctatctc ttctaaattt
     2941 tcaaccacag gacttggata aaggataatc tgactatcct tgtaatcaaa attccatgca
     3001 gacaagtctt ggtcagagaa gttttttaca atctgctcac tctggtcttg ctctattttt
     3061 ttatcctcta tgaaggaggt caactctttt atcagctgtt ccttagcctt actagcatcg
     3121 gaaaacagtt ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac ctttcctaga
     3181 ctggtctttt cagtctcttc aaccttaaaa gcaactaaat catagatttg tttggtcaca
     3241 ttacgattaa cgactccctt taaacctgac tcttcttgct ctgtatagta gaaaacaaga
     3301 ttgtccttac tttctagctt gtccttaaca tcttgattta tcaactccct aacagaggaa
     3361 atcactttct ccccttggag aggataatag gcaatcactt cggcttgccc ctgacgaaaa
     3421 tgctccttct gatttccctc actcaattga tcatctttct cttttttgag cgattcaatc
     3481 ttttgctcaa aacttttttg ctggtagatc ttaaaagcaa taaatccgcc taataggcaa
     3541 atagaaattg ctaaaatacc aatcaaagcc aataatacat gtctcgtttt cccgtgtctg
     3601 ccacgtccta gtctactttt attcatattt atatcataac aaatttgagc aataatttca
     3661 atgatacaat ttggcaatcc acaattcctc tagcaagcca aagcatctta catcaactcc
     3721 aacatccgta tctgtagaga ttatgtagtt ttctatctat ggaatttcta gtagattgaa
     3781 gctagaatag tagacctata cttctaaaac attgttagaa atcgatttga ttgtcctgat
     3841 cgatttgtcc tgttctcatt tcattttact ataaaactat gaaaagctag gtcatctgag
     3901 aagtaattac tatcgacaat tgcgatagcg tatactggtg cgatttgttt gtagctctgg
     3961 tgggtatcac cttcacgttg gcgaattttt tctaggtttt gattaacctg actgcacaga
     4021 taagcccata ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc gatgataact
     4081 tggattccat tatctaactc cgccaagacg tctatactag tatagaaatc ctgcgctgag
     4141 tagggcatgg aaggcaagac gtgaatgtta cttccctcca aaatcgtcac attttttgct
     4201 ggcaagtcca gcatatcgcg gataaattga caaatcatta gttgggctga tacccggatg
     4261 tctgagaatc ctccttttcc tccttctatt atagcacatt agaaagctaa tagcttattt
     4321 gaaattttct cctctctgtt ggatagtccc gtctatctat gttataatga aagaaggatt
     4381 taaaatcgga aaaggagtat ttatgctaaa attaggtgtc atcggaactg gcgctatcag
     4441 ccatcatttc atagaagcag cccataccag tggagaatac caactggtcg caatctattc
     4501 tagaaaacta gaaactgcag caacctttgc ttctcgctat caaaataccc aactattcga
     4561 tcaattagaa gtcttcttca aatcttcttt tgatttagtc tatatcgcca gtccaaactc
     4621 cttacatttt gctcaggcaa aagctgcctt gtctgctggt aaacatgtta ttcttgaaaa
     4681 gccagctgtc actcaaccac aagaatggtt tgatttgatt caaacagctg aaaaaaataa
     4741 ctgttttatc tttgaagcag ctcgtaatta tcacgagaaa gcctttacta ctatcaaaaa
     4801 ctttttagca gataagcaag tgttaggagc agatttcaac tatgccaaat actcttccaa
     4861 gatgcctgac ttgttggctg gacaaacacc aaatgtcttt tcagaccgtt ttgctggtgg
     4921 agccctcatg gatttgggga tttatcccct ctatgctgct gttcgtcttt ttggaaaagc
     4981 caatgacgcg acttaccatg ctcaacagct tgacaatagc attgacctaa atggagatgg
     5041 tatcctcttc tacccagact atcaagttca catcaaggct ggaaaaaaca tcacttccaa
     5101 tcttccttgc gagatttata caacagatgg aaccttgact ctcaacacga ttgagcatat
     5161 tcgctcagct atttttaccg accaccaagg aaatcaagtc cagcttccta tccaacaggc
     5221 tcctcatacg atgactgagg aagtcgctgc atttgcacac atgatccagc aaccagatct
     5281 gaatctctac caaacttggc tgtatgatgc aggctctgtt catgagctac tatataccat
     5341 gcgccagact gctggcatta gatttgaggc agaaaaatga aaaccaaact accgactgaa
     5401 tggcaagaac tgagtgacca actcggtttc caagaattca cccccattca aactcaacta
     5461 tttgagcccc ttcttgctgg agaaaacctc ctaggagtga gccaaaccgg aactggtaag
     5521 accctagcgt atctcctacc aagtcttctc agactacaaa agaaaaaagc ccaacaactc
     5581 ttgattctag caccaaatac ggaacttgct ggacagattt ttgatgtatg taaaacgtgg
     5641 gcagaagcta tcggattgac tgctcaactc ttcctttcag gttcaagtca gaaacgacaa
     5701 attgaacgtc ttaaaaaggg gccagaaatt ctgattggaa ctcctggccg tatctttgaa
     5761 ctcattaaac ttaaaaaaat caagatgatg aatgtggaaa ccatcatcct ggatgaattt
     5821 gaccaattac tagatgattc tcagattcac tttgtagaaa aaatcactca ctacgcacct
     5881 cgtgcccacc aactggtcta catgagtgcc acgaccaagt ttgaccaaga aaagattgtg
     5941 ccgaatacac gcactattga tctctctgat caaaaattgg acaatatcca gcatttctac
     6001 atgcaggtag accaacgtca tcgagtggat atgctacgaa aactggctca tgtagaggat
     6061 ttccgtggtc tagtcttctt caatagcctg tcagaccttg ggaatgccga ggaaaaacta
     6121 cagtatcgtg atatattggc tgtttccctc gctagtgatg ttaatgttaa atttagaaaa
     6181 gtcatcttag aaaagtttaa agataaccaa ctaaccctgc ttcttgcaac tgaccttttg
     6241 gctcgtggaa ttgatatcga tagcctagaa tgtgtcgtaa actttgatat tcctagagat
     6301 agcgaaacct acacacaccg tgctggccgt actggccgta tgggcaagga aggatatgtt
     6361 attactctcg tcactcatcc agaagaaatc aaaaaactta aaaagtttgc aagtatccga
     6421 gaaattgtcc taaaaaacca agaactctat atcaaataaa gccccattgc tctatacaca
     6481 tccagtgtat ggagcttttt tataagcaat tcaattttat actcatctgc tttcaaaaag
     6541 cattctagtc catctccgat taacgatgga ctttatcacc tccttctcca gtccttgtat
     6601 aacatcttgg agttgattca tgacatcttc caaagttcga aaggctttat tcttaaatcc
     6661 acgtttacga atctctttca acacttgttc aatgggttca tctctggtgt gtatggagga
     6721 ataaatgcaa agccaatatt agtcggaatc tttaaggtac ttgatttatg ccatatagca
     6781 ttgtccataa cgagtaaaag ataatcatct ggataagctt gtgaaagctc ttctaaaaag
     6841 gcgttcatcc actcagtatt acatccacca gctattaaga aaaatgattc gcctgtatag
     6901 gcatcaacag ctccataaca atagcgaaat tctcgtatat agtgactatg gacatgtgga
     6961 cctactccta ttggagacca acaagatccc agtttactga ttctaccgaa accagcctca
     7021 tcttggtaca tcaagcgaac cttacgaaaa cgtctactat atttaaaacg ctttcttgtc
     7081 ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg ctttcttagg
     7141 attttctgga cgtggcataa tatttcgcca accatggcgc ttcaacagtt gatagaaggc
     7201 atcacgtgtg taggaacgac ctaactcctt tttataagcc tgaaataagg catcaattgt
     7261 aacaaattct cctgcctctg cagccttcaa atggcgggca agaaagactt tttcttcctc
     7321 aactgtcata tatgcatggt tacgaccacc acgtgtttct tgaaggagag agtcgggtcc
     7381 gaactcctca tattttttta catttcgcca aatcgttgtt tgattacagt ctaaaagttc
     7441 tataatctct ttataagatt tgcccatcag acgaaatata gtagattgaa actagaatag
     7501 tgcacctcta cttctaaaac attgttagaa atcaatttga ctgtcctaat cgatttgtac
     7561 tgttcttatt tcattttact atagaacgat ttgaaggtgt ttatgatatt tagctgtact
     7621 agagtttttt aaaagtgttt tgatggtttg gatttcttct ttaattgatt tcatattact
     7681 attgtataat gctttttgat tttagtctag tataaatag
//
LOCUS       DAVDFK010000060         7636 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.60, whole genome shotgun sequence.
ACCESSION   DAVDFK010000060 DAVDFK010000000
VERSION     DAVDFK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.60"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            477..2582
                     /locus_tag="VUR04_001873"
     CDS             477..2582
                     /locus_tag="VUR04_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5341716.1"
                     /translation="MNNNFNNFNNMDDLFSQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(2878..3360)
                     /locus_tag="VUR04_001874"
     CDS             complement(2878..3360)
                     /locus_tag="VUR04_001874"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET5341717.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(3455..4939)
                     /locus_tag="VUR04_001875"
     CDS             complement(3455..4939)
                     /locus_tag="VUR04_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET5341718.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PINLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            5091..6698
                     /locus_tag="VUR04_001876"
     CDS             5091..6698
                     /locus_tag="VUR04_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET5341719.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDRLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENKKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTDQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            6857..7030
                     /locus_tag="VUR04_001877"
     CDS             6857..7030
                     /locus_tag="VUR04_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET5341720.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(7023..7636)
                     /locus_tag="VUR04_001878"
                     /pseudo
     CDS             complement(7023..7636)
                     /locus_tag="VUR04_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2302 a         1422 c         1722 g         2190 t
ORIGIN      
        1 taaaatattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt cttatttcat
       61 tttaatatat agttttgaga tggttgatag aactgacgaa gtcagctcaa aacatggttt
      121 tgaggttgta gataaggaga agctgatgtg gtttgaagag gttttcgaag agtgtaaaaa
      181 aatattggtc agttaaagtc aaaactcttg accttttctg accaatgtag tatattatga
      241 acgtaaggta aatgaaagcc ttactagaac acttatttaa agtaaaatag aaagaggtgg
      301 gtctatgttt catctagaaa tcttcagaag taaagatggt ctactcctgc ttgaaaaaga
      361 aaaaccagaa atagtacgta gggtagcggt ttaactagtc taaatttttt aaaacaatgg
      421 tcaaagatag tcaatatcag taatcataac taagtaaaca aaaagaggta aagaatatga
      481 ataacaactt taataatttt aataacatgg atgatttatt tagccaattg atgggtggta
      541 tgcgaggata tagttctgaa aatcgccgtt acttaattaa tggacgcgaa gtcacacctg
      601 aggaatttgc tcactatcgt gcgactggtc aattaccagg aaatgcagaa actgatgtgc
      661 aaatgccaca acaggcatca ggtatgaaac aagacggtgt ccttgcaaaa ctaggtcgaa
      721 acttgacagc agaagcgcgt gagggcaagt tggatcctgt tatcggacga aacaaggaaa
      781 ttcaagaaac atctgaaatc ctctcacgcc gcaccaagaa caatcctgtt ttggtcggag
      841 atgcaggtgt tggtaagaca gcagttgtcg aaggtctagc gcaagccatt gtgaacggag
      901 atgttcctgc tgctatcaag aacaaggaaa ttatttctat tgatatctca ggtcttgagg
      961 ctggtactca ataccgtggt agctttgaag aaaatgtcca aaacttagtc aatgaagtga
     1021 aagaagcagg gaatattatc ctcttctttg atgaaattca ccaaattctt ggtgctggta
     1081 gcactggtgg agacagtggt tctaaaggac ttgcggatat tctcaagcca gctctctctc
     1141 gtggagaatt gacagtgatt ggggcaacaa ctcaagacga ataccgtaac accatcttga
     1201 agaatgctgc tcttgctcgt cgtttcaacg aagtgaaggt caatgctcct tcagcagaga
     1261 atacttttaa aattcttcaa ggcattcgtg acctctatca acaacaccac aatgtcatct
     1321 tgccagacga agtcttgaaa gcagcggtgg attattctgt tcaatacatt cctcaacgta
     1381 gcttgccaga taaggctatt gaccttgtcg atgtaacggc tgctcacttg gcggctcaac
     1441 atccagtaac agatgtgcat gctgttgaac gagaaatcga aacggaaaaa gacaagcaag
     1501 aaaaagcagt tgaagcagaa gattttgaag cagctctaaa ctataaaaca cgcattgcag
     1561 aattggaaag gaaaatcgaa aaccacacag aagatatgaa agtgactgca agtgtcaacg
     1621 atgtggctga atctgtggaa cgaatgacag gtatcccagt atcgcaaatg ggagcttcag
     1681 atatcgaacg tttgaaagat atggctcatc gcttgcaaga caaggtgatt ggtcaagata
     1741 aggccgtaga agttgtagct cgtgctatcc gtcgtaaccg tgctggtttt gatgaaggaa
     1801 atcgcccaat aggcagcttc ctctttgtag ggtctactgg ggttggtaag acggagcttg
     1861 ctaagcaatt ggcactcgat atgtttggaa cccaggatgc gattatccgt ttggatatgt
     1921 ctgaatacag tgaccgcaca gctgtttcta agctaattgg tacaacagca ggctatgtgg
     1981 gttatgatga caatagcaat accttaacag aacgtgttcg tcgcaatcca tactctatca
     2041 ttctcttgga tgaaattgaa aaggctgatc ctcaagttat tacccttctc ctccaagttc
     2101 tagatgatgg tcgtttgaca gatggtcaag gaaatacagt aaacttcaag aacactgtca
     2161 ttattgcgac ctcaaatgct ggatttggct atgaagccaa cttgacagaa gatgcggata
     2221 aaccagaatt gatggaccgt ttgaaaccct tcttccgtcc agaattcctc aaccgcttta
     2281 atgcagtcat cgagttctcg cacttgacta aggaagacct ttctaagatt gtagatttga
     2341 tgttggctga agttaaccaa accttggcta agaaagacat tgacttggta gttagtcaag
     2401 cggctaaaga ttatatcaca gaagaaggtt acgacgaagt catgggggtt cgtcctctcc
     2461 gtcgcgtggt tgaacaagaa attcgtgata aggtgacaga cttccactta gatcatttag
     2521 atgctaaaca tctggaagca gatatggaag atggcgtttt ggttattcgt gagaaagcct
     2581 aagatagaat tttgaggata aaaaagaagg agccagctga aaaaaactgg ttccttttta
     2641 ggtacgacag gcatgtcgta tagtagaagt gtattattcc agtttcaata tactatagta
     2701 tctcagaagt cggtacttaa acgtgctata tcaaaaccag tccttgagaa acgtggactg
     2761 gtttcgtgtt tggattatta ccttgaacga catacgttaa aagttagttg aaccgccgta
     2821 tgccgaacgg cacgtacggt ggtgtgagaa gggctagaga ttatccccta ctcgatttta
     2881 aatcacatga cgttcaaagg catcatctga aatcccttgt tccaagatga gttttgccca
     2941 ttctttagca gagaagaggc tgtggtcttt gtagtttccg caagattcga tggttgtccc
     3001 tgggacatct tcccaagtag tagtttcagc gatttccttg agcgaatcct tgataacagc
     3061 tgcgatttta gcactggtgt gacgtcccca cataatcatg tggaagcctg tgcggcaacc
     3121 aaatggtgaa cagtcaatca tgccgtcaat gcgggtacgg atgagtttgg ctaagaggtg
     3181 ctcgatagtg tgaaggccgg cagtagggat agagtcttcg tttggttgca ccaagcgaat
     3241 atcataattg gagatgatgt ctccttttgg tcctgtttct tccccaatca agcgaacata
     3301 gggtgctttg acaatggtgt ggtcaagttc aaaactttcg acaataactt cttttgacat
     3361 tgtaaatcct ttcagttttc ttctctcatt atatcataaa ggttgttcct gagacagaga
     3421 gaaaacctct ccgaggctag agaggttgaa atctttactt acgatataag cggtcgtatt
     3481 ggtagtatgg gtcaaaggtt acgttgatac ccagtttacg aaggacattc ttgtcttcat
     3541 cagtcaagat gatggttgag tgggcttcgc ttcctttgag gttgccgagt tcttccatag
     3601 cgcgggcagc atcaggattt tctgtagctg tgatagcaag tgcaatcagg atttcatttg
     3661 aatgaaggcg tggattgcgg ctaccgagat gatcgatttt aagaccttgg attggcttaa
     3721 caacttcagg ctcgattagt tttacttctt tagcgatgtc agctgatttt ttgatggcgt
     3781 tgatcaaggc agcggctgta ggcccaaaga gttctgagtt cttaccagtg acgatttccc
     3841 catttggcaa ttcaaaggct agggctggtc caccagtttc ttctgctttt tggcgcgcaa
     3901 cgacagcaac cttacggtct gcaggtgtga taccgaggtc gttcatgagc aactcaattt
     3961 tcttgacggc agcttcgcca actttttcag ctttgaagtc aagaactgtt tgatagtaac
     4021 ggcggatgat ttcttgttta gaagcttcga cagcggcctc gtcatctgta atagcgaaac
     4081 caaccatgtt gacacccata tctgtcggtg aagcgtatgg tgattttccg agaatacgtt
     4141 ccaacatgcg cttgagcact gggaagattt cgatatcacg gttgtagttg acagtggttt
     4201 ctccataggt ttgaagatgg aaggggtcaa tcatgttgac atcatcaagg tcagctgtgg
     4261 cagcctcgta ggccaagttg atagggtgat gaaggggcag attccagact gggaaggttt
     4321 caaatttagc gtagccagac ttgataccat tgatttggtc gtgatacata ttggacatac
     4381 acgttgccaa ttttccagaa ccaggtccag gagcggttac gacaatcaag ttgcgactgg
     4441 ttttgatgta gtcatttttc cccatacctt caggagaaat gatgtgatcc atatccgtcg
     4501 gatatccttt gattggataa tgaagataag aatcaattcc atttttctca agttggttgc
     4561 ggaaggcatc tgcagcgggt tggccagcgt attgtgtaat gacaacggaa ccaacaaaaa
     4621 tccctaattc attgaatttg tcaatcaaac gaagaacttc ttggtcataa gaaatgccta
     4681 agtcgccacg tgctttggaa tgttcaatgt tgctagcatt aatggcaatc acaacctcaa
     4741 cctgctcttt caattcttgc aagagcttga ttttgttgtc aggttcataa ccaggaagga
     4801 cacgagcagc gtggaaatct tctaacattt taccgccaaa ctctaagtag agcttgccgt
     4861 caaattggtt aatgcgctcc aaaatatggt cgcgttgtaa attcaaatat tgttcagaac
     4921 taaaagcttg ttttttcatt ttttacctct ggactctatt ataataaaaa attggaagtt
     4981 aggaaactac ggagctaaaa aagaaattaa aaagattaag caaacgcttg cacaaaattt
     5041 taaaaagtgc tatcatatac tatagattat taaaataatg aggtaagaag atgcaagaaa
     5101 aatggtggca taatgccgta gtctatcaag tctatccaaa gagttttatg gatagtaatg
     5161 gagatggagt tggtgatttg ccaggtatta ccagtaagtt ggactatcta gctaagctag
     5221 gaatcacagc gatttggctt tctcccgttt atgacagccc tatggatgat aatggctacg
     5281 atattgctga ttatcaagcg attgcaacga tttttggaac catggaggat atggatcgac
     5341 tgattgcgga agctaagaag cgtgacattc gtatcatcat ggacttggtg gttaatcata
     5401 cctcagatga acatgcttgg tttgtcgaag cttgtgaaaa tactgacagc cctgagcgag
     5461 actactatat ctggcgcgat gaacccaatg acctagattc tatctttagt gggtctgctt
     5521 gggaatacga tgaaaagtca ggtcaatact atctccactt tttcagcaag aaacagccgg
     5581 atctcaactg ggaaaataaa aaacttcgcc agaaaattta tgagatgatg aacttctgga
     5641 ttgataaagg tattggtggt ttccgtatgg atgttattga catgattggc aaaattcctg
     5701 acgagaaggt agtcaataat ggtcctatgc tccatcccta tctcaaggaa atgaatcagg
     5761 cgacctttgg agataaggat ctcttgacag taggggagac ttggggagca acgccagaga
     5821 ttgccaagct ctactctgat ccaaaggggc aagaattgtc tatggtcttc cagtttgaac
     5881 atatcggtct tcagtatcag gaaggtcagc ctaaatggca ctatcaaaaa gagctgaata
     5941 tcgctaagtt aaaagaaatc ttcaacaaat ggcagacaga gttaggagtt gaggacggct
     6001 ggaattccct cttctggaac aaccatgacc tccctcgtat tgtctcaatc tggggaaatg
     6061 accaagaata ccgcgaaaaa tctgccaaag cctttgcaat cttacttcat ctcatgagag
     6121 gaactcctta tatctaccaa ggtgaggaga ttgggatgac caactatccg tttgaaacac
     6181 tagatcaagt agaagatatt gaatccctca actatgcgcg tgaggctctt gaaaaaggtg
     6241 ttccgattga agaaatcatg gacagtatcc gtgttattgg acgtgacaat gcccgtaccc
     6301 ctatgcaatg ggacgagagc aaaaacgctg gtttttcaac agatcaacct tggttggcag
     6361 ttaatccaaa ttacgagatg atcaacgtcc aagaagcgct ggcaaatcca gattctattt
     6421 tctataccta tcagaaactg gtccaaattc gcaaggagaa tagctggcta attcgagctg
     6481 actttgaatt gcttgatacg gctgataagg tctttgctta tatacgtaag gatggcgacc
     6541 gtcgcttcct agttgtggct aacttgtcca atgaagagca agacttgaca gtagaaggaa
     6601 aagtcaaatc tgtcttgatt gaaaacaccc tagctcaaga agtctttgaa aaacaaatct
     6661 tagttccatg ggatgctttc tgtgtggaat tactataaat attttttgca gaaaaattta
     6721 aaattgaaat catataaaaa caagggagga ctgtataaaa ggcggaaatc ctttgttttt
     6781 tataaccaag gtttataaac tttcattctc gaaattcaat taactttaca aattcccact
     6841 attaaggaga aagaagatga acataaagaa gcgtgtcctt agtgcaggcc tgacttttgc
     6901 atctgctttg cttttagctg cttgcggcca atcaggttca gatacaaaaa cttactcatc
     6961 aacctttagt ggaaatccaa ctacatttaa ctatctatta gactattacg ctgataatat
     7021 agttaattga aacaagaaca agacaaaaga gcctcgtaaa aggtattgca acttggtaat
     7081 acctttttgg ggtgcttttt gatatgagcc catgttttct caataggatt gtactcaggt
     7141 aagtagggag gaagaggtaa aagtttatgc ccaaactctt cgcataaaag ttctagcttc
     7201 cccattctat ggaatcttgc attatccata ataataaccg atggtgtggt taatgttggt
     7261 aagagaaaat tctgaaacca agcttcaaaa aagtcgctcg tcatcgtctc ttcgtaagtc
     7321 attggaacga ttaactcacc atttgttagc cctgcaacca aagaaatcct ctgatatctt
     7381 cttccagata ctttgcctct tattaactga ccttttaaag agcgaccata ttctcgataa
     7441 aaataagtat cgaatcctgt ttcgtcaata taaacaggtg ctaggtgctt taaactatta
     7501 aattcttaag aaataaggct actttttctg ggtcttgttc atagtaggtg tggttctttt
     7561 tttcgagtgt agcccacagc tttgagcgca tagtggatgg tagttggatg acagccaaat
     7621 tcagaagcta tttcag
//
LOCUS       DAVDFK010000061         7242 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.61, whole genome shotgun sequence.
ACCESSION   DAVDFK010000061 DAVDFK010000000
VERSION     DAVDFK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.61"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..587
                     /locus_tag="VUR04_001879"
                     /pseudo
     CDS             1..587
                     /locus_tag="VUR04_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(584..829)
                     /locus_tag="VUR04_001880"
     CDS             complement(584..829)
                     /locus_tag="VUR04_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET5341721.1"
                     /translation="MEQSPQKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(844..2016)
                     /locus_tag="VUR04_001881"
     CDS             complement(844..2016)
                     /locus_tag="VUR04_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET5341722.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGANPI"
     gene            complement(2075..2920)
                     /locus_tag="VUR04_001882"
     CDS             complement(2075..2920)
                     /locus_tag="VUR04_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5341723.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            3045..3602
                     /locus_tag="VUR04_001883"
     CDS             3045..3602
                     /locus_tag="VUR04_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET5341724.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            3621..4088
                     /locus_tag="VUR04_001884"
     CDS             3621..4088
                     /locus_tag="VUR04_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET5341725.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            4177..4806
                     /gene="upp"
                     /locus_tag="VUR04_001885"
     CDS             4177..4806
                     /gene="upp"
                     /locus_tag="VUR04_001885"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET5341726.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            4980..5570
                     /gene="clpP"
                     /locus_tag="VUR04_001886"
     CDS             4980..5570
                     /gene="clpP"
                     /locus_tag="VUR04_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET5341727.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            5649..5897
                     /locus_tag="VUR04_001887"
     CDS             5649..5897
                     /locus_tag="VUR04_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET5341728.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            5999..7159
                     /locus_tag="VUR04_001888"
     CDS             5999..7159
                     /locus_tag="VUR04_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5341729.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
BASE COUNT         2275 a         1400 c         1517 g         2050 t
ORIGIN      
        1 tgattttggt atccacgaaa gcaacttact ccgtcggagc caatgggttg aagtaactct
       61 tgttcaaagt ggttttacgg tttcaagaac tcctctcagt tctgaggaca cggtaatgat
      121 tgatgcgacg gaagtaaaaa tcaatcgccc taaaaaaaca attagcgaat gattctggta
      181 aaaagaaatt tcacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt
      241 ctttggatat cgctgtgaac tatagtcatg atatgaagtt gttcaaaatg agtcgtagaa
      301 atatcgaaca agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat
      361 atcctcaagc acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gctgaagata
      421 aagcctataa ccatgcgcta tctaaggaaa gaagcaaggt tgagaacatc tttgccaaag
      481 taaaaacgtt taaaatattt tcaacaacct atcgaaatca tcgtaaacgc ttcggattac
      541 gaatgaattt gagtgctggt attatcaatc atgaactagg attctagttt tgcaggaagt
      601 ctaatagagt atgaacctgt tctcgtattt cttcgagagc taagttactt tcaagaataa
      661 tatttccact ttgaatataa gttcgaactt gttgaaaatc agcttctgtc aagatatcta
      721 ctagataaga cattttaggg atagcatttt ttccattagg agtgactccc cttagcaaga
      781 taatatgttc caaagtagtt cctttctttt tttgggggga ttgttccatt tagtaatgta
      841 tatttagatt ggatttgctc ccgccaccca gccggtacag agggcagaag tgatgttaaa
      901 gccacccgtg tgggcattga tatccataac ttcgcctgca aagtggaggc caggtaccag
      961 cttactttca agggttttag gattgatttc cttgagactg actccaccct tggtaacaaa
     1021 ggactttgca agggacattt ttccagttac aggaatttta agttctttaa tggactggac
     1081 aagttgttct cgttcctttt cagtcagttg tttgactttt tcaggatatc cttgtacaaa
     1141 aaattcggcc aagcgttctg gtaacaaggt ttttaaagcg tttttcaagg atttttcccg
     1201 attttcttct agaaatgtaa ccaagtcctt ctcagaaagt tgaggcaaaa catcgagtga
     1261 gagaacctcc ccacctttga caaagctaga catgcgtagg gcagcaggac ctgacaaacc
     1321 aaagtgggta aagagtaaat catgagtgat gacatgctta ccataactta gggtcacatc
     1381 gtccagagaa atcccttgta aggctttatg tggaaaatct gttaataaag gactttcagc
     1441 agcctcaaga tcggtgatgg tatgcttaaa atggcgagca atctcgtgac caaaaccagt
     1501 cgaaccagtc gaaggataag acttaccacc tgttgtgaca atgagtttct cacaagtgaa
     1561 ggtttgatcc gctgacttaa ggacaaactg gtcatctact tttttaacag aaacgatttc
     1621 tatttgagta gcaacttgac cacctagttc ggtgattttc ttttccaaag cttcgataat
     1681 agtccgagac ttgtcactgg ctggaaagac gcgtccgtgg tcttcgacct taagtttaac
     1741 accattttct gtaaaaaagt tgatgatgtc atgattatcg aactgggaga aaacactgta
     1801 aagaaagcgt ccgtttccag gaattccagc tagcaggttg tctaagctac cattgttggt
     1861 cacattgcaa cgtcccccac cagtcccagc taattttttt ccaagtttcc gatttttttc
     1921 gatgaggagg gttttctgtc cataaaagct actggaaatc gtagccatca taccagcagg
     1981 tcccccaccg atgacaatag tatcaaaatg tttcatagct ctattgtacc acaaaaaaac
     2041 aagagatgat ggtcacctct tgtcaagaat gcaattaatc aatttcatag cccatcagca
     2101 aaccgccctc ttctgcatag aaactgcaga gaccagaggt tggtagaatt ttaatatccg
     2161 cttgtgggaa ggtttcacgg attcgctctg agagctgttg acaacatttt tcgttattgc
     2221 gttgggccat gacaatacgg ccaccagcat atccagcttt tactaactca tcataggcag
     2281 cttgaactga tttctttgat ccccttgctt tttgtagcaa ttcgagagtc ccagtttcac
     2341 tagcttttcc gaccatacga atgttgagaa ggccaacgac cgtaccgata agcttgctca
     2401 aacggccgtt cttcaccaag ttatcgactt tggctaggac aaagagcaac ttagtttttt
     2461 cttgataggc ggtgatagct tcaaccactt cttcaaaaga caagccctgg tcaatcaagt
     2521 cattcaattt ttctacgagt aggtcaactt caccaccagc agataaacta tcaatcacat
     2581 gaatcttagt gtcaggatgg tcttccagat aaatattctt tgctagttga gcactattgt
     2641 gactgccaga aagggtacct gtgatggtta ctaggaaaat gtttttggca ccttcaaatg
     2701 ctcgcaaata gtcatctggg cttggacaag ccgattttga agcttctgca gttgcataca
     2761 tggtttccat catttggtca atatcgagac tggcgtcatc aacaaagacc tgatcagcta
     2821 cttgaatggt taaggggacg cttacaaagg ttgtgttaat agctggtgtt ggcagttgac
     2881 gataatcaca accagagtca gcaataattt tccaagtcat agaaattctc catctttgtc
     2941 agttatacat tgacaaaggt tctgtctttt tttacaatta tatcatgaaa acccttgaaa
     3001 caaaagcatc atccgtctgt tgtgacaagt agaaagaaaa tgttatgtct gaacgtagaa
     3061 tctctgaaaa gtctcttgaa aatctcagaa aatcaaacca agaatccaat ttattaacca
     3121 gagaagccat tgaaacagcc ctcttgcaac tcttggaaaa aaaggagctg accaagatta
     3181 gtatttctga attggtcaaa cgtgcgggtg tttcgcgtgc ggccttttat cgcaattatg
     3241 actccaaaga ggaaatttta gagagcgtct ttaaacgaac tgtccacaat attatggaac
     3301 agctgcatca ttacgattta aagacagacc tttatttggt ttgggttcac cttttccggg
     3361 aggccagaaa ggaagctaga gtgattcaat tggccttgga ttaccatctg gaaaaaatct
     3421 ttgtccaagc catgcaggaa tttctagaaa aataccatgg gaaatcaaaa ggtgtcagct
     3481 cttatcttca ttccttctgg agctcagcca tcgtctctgt ccttctaaaa tggatcaagg
     3541 atggcatgaa ggtaccagct gaaaagattg cagatttagg tttaccattt tttaaaaaat
     3601 agagaaaaag gagaaaagag atgactgaaa aaagactggc ctgggatgag tattttgcag
     3661 cccaagccct actaattgcg aatcgttcca cttgtaaacg tgctaaagtg ggcgcgattc
     3721 tggtaaaaga taataaggtt atttccactg gttacaatgg ttcggtgtca gggactgagc
     3781 attgtattga tcacgaatgt ttggtcattg aaggccactg tgttcgcacc cttcacgctg
     3841 aggtcaatgc tatccttcaa ggtgctgagc gtggtgttcc caaaggcttt acagcctatg
     3901 taacccattt tccttgtctc aactgtacaa aacaattgct tcaggtcggc tgcaagcgtg
     3961 tggtttatat caaccagtac cgaatggacg actacgccca atacctttat caagaaaaag
     4021 ggacagaatt gacccattta ccacttgaga cagtacagac agctcttaaa gaggctgatc
     4081 taatgtaaaa attatcaaaa ataaatggtt tagaaagatt tttaaaccgt tttttggtat
     4141 aataagaaga ataaattgaa agaaggaatt ccaaaaatgg gaaaaattga agttattaat
     4201 cacccactga ttcaacacaa attgtcaatc ttgcgtcgta cagatacttc tacaaaagct
     4261 tttcgtgagc tagtagatga gattgcaatg ttgatggggt atgaagtact tcgtgatctt
     4321 ccactagaag atgtggaaat cgaaacacca attacaaaaa cagttcaaaa acaattggca
     4381 ggtaagaaat tggccatcgt cccaatcttg cgtgcaggta tcgggatggt tgatggtctc
     4441 ttgagcttgg ttccagctgc taaagttggc cacatcggta tgtaccgtga tgaagaaaca
     4501 cttcaaccag ttgaatactt ggtgaaattg cctgaggaca ttgaccaacg tcaaattttt
     4561 gtagtagacc caatgttggc aacaggtggc tcagcaatct tggctgttga ttctcttaaa
     4621 aaacgtggcg catcaaatat caaatttgtc tgccttgtat ctgctccaga gggtgtaaaa
     4681 gcccttcaag aagctcatcc agatgtagaa atctttacag cagccttgga tgaacgtttg
     4741 aacgaacacg gttatatcgt tccaggtctt ggagatgctg gagaccgctt gttcggtaca
     4801 aaataagatc gaaaagaaga atgacttgga aaagtatttc cagtcacgaa aggaggttgg
     4861 gtttttgttt ctgtctaatg aaagcagagc aaaaatttga ccttttttga ccaagatatt
     4921 ataatagtct tatcttcagt catttgacca acaaaattaa aactcaaaag gagaaatgaa
     4981 tgattcctgt agttattgaa caaacaagcc gtggagaacg ttcttacgat atttactcac
     5041 gtcttctcaa agaccgcatc attatgctga caggtccggt tgaagacaat atggctaact
     5101 ctgttattgc ccaactgctt ttcttggatg cccaagatag tacaaaagat atttaccttt
     5161 atgtcaatac accaggtggt tctgtttcag ctggtttggc aatcgtagat accatgaact
     5221 ttatcaaggc agatgtccaa accattgtta tgggaatggc tgcatctatg ggaacagtca
     5281 tcgcatcaag tggagcaaaa ggcaaacgtt tcatgcttcc aaatgctgaa tacatgattc
     5341 accaaccaat gggcggtaca ggtggtggta cccaacaaac tgatatggct atcgctgcag
     5401 aacacttgct caaaactcgt aataccttgg aaaaaatctt ggctgaaaat tcaggtcagt
     5461 caatggaaaa agtccatgca gatgcagaac gtgataactg gatgagcgcc caggaaacac
     5521 ttgaatatgg ctttattgat gaaattatgg ccaacaattc attgaactaa tgatgataga
     5581 aggcaaactc gactgggttt gctttttttg gtataatagg gagagatttc ttagaaagag
     5641 gatttatcat gtttgaaaaa gtcaatcgct ctggcttgat tatctatctt tactataatc
     5701 gtgatgccaa aaaactgcag gattatggag atattaccta tcattccaag aaacatcgtt
     5761 acttacaact ctatgttcca actcaagaag tggagcaatt ggtcggacgc ttgagcaagg
     5821 aaaaatttat taaaaaagtt agggtttgtc atatccaaga gttggaaaca ccctttgtgg
     5881 gcaatcttta tcgataggaa aacgctatca tcgaaaaagt tcaaggaaaa cattgacaat
     5941 tttctgataa ttcggtatat tcttaacaga ctatttaaga aataaggaga caaaaaagat
     6001 gaagaaaaaa tttgccctat cgtttgtggc gcttgcaagt gtagcacttc ttgcagcctg
     6061 tggagaagtg aagtctggag cagtcaacac tgctggtaac tcagtagagg aaaagacaat
     6121 taaaatcggg tttaactttg aagaatcagg ttctttagct gcatacggaa cagctgaaca
     6181 aaaaggtgcc caattggctg ttgatgaaat caatgccgca ggtggtatcg atggaaaaca
     6241 aatcgaagta gtcgataaag ataataagtc tgaaacagct gaggctgctt cagttacaac
     6301 taaccttgta acccaatcta aagtatcagc agtcgtagga cctgcgacat ctggtgcgac
     6361 tgcagctgcg gtagcgaacg ctacaaaagc aggtgttcca ttgatctcac caagtgcgac
     6421 tcaagatgga ttgactaaag gtcaagatta cctctttatt ggaactttcc aagatagctt
     6481 ccaaggaaaa attatctcaa actatgtttc tgaaaaatta aatgctaaga aagttgttct
     6541 ttacactgac aatgccagtg actatgctaa agggattgcc aaatctttcc gcgagtcata
     6601 caagggtgaa atcgttgcag atgaaacttt cgtagcaggt gacacagact tccaagcagc
     6661 ccttacaaaa atgaaaggga aagactttga tgctatcgtt gttcctggtt actataatga
     6721 ggctggtaag attgtaaacc aagcgcgtgg tatgggaatt gacaaaccaa tcgttggtgg
     6781 tgatggattc aacggtgagg agtttgtaca acaagcaact gctgaaaaag catcaaacat
     6841 ctactttatc tcaggcttct caactactgt agaagtttca gctaaagcta aagccttcct
     6901 tgacgcttac cgtgctaagt acaatgaaga gccttcaaca tttgcagcct tggcttatga
     6961 ttcagttcac cttgtagcaa acgcagcaaa aggtgctaaa aattcaggtg aaatcaagaa
     7021 taaccttgct aaaacaaaag attttgaagg tgtaactggt caaacaagct tcgatgcaga
     7081 ccacaacaca gtcaaaactg cttacatgat gaccatgaac aatggtaaag ttgaagcagc
     7141 agaagttgta aaaccataat agaaaaatgt tgaaataggg aatgagcctt tgactcactc
     7201 cctgtttcga tatttaatac tcttcgaaaa tctcttcaaa ct
//
LOCUS       DAVDFK010000062         7196 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.62, whole genome shotgun sequence.
ACCESSION   DAVDFK010000062 DAVDFK010000000
VERSION     DAVDFK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.62"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(441..700)
                     /locus_tag="VUR04_001889"
                     /pseudo
     CDS             complement(441..700)
                     /locus_tag="VUR04_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(703..1203)
                     /locus_tag="VUR04_001890"
     CDS             complement(703..1203)
                     /locus_tag="VUR04_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5341730.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGFDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            1239..1418
                     /locus_tag="VUR04_001891"
     CDS             1239..1418
                     /locus_tag="VUR04_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341731.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(1396..2364)
                     /locus_tag="VUR04_001892"
     CDS             complement(1396..2364)
                     /locus_tag="VUR04_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET5341732.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(2450..2665)
                     /locus_tag="VUR04_001893"
     CDS             complement(2450..2665)
                     /locus_tag="VUR04_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET5341733.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(2674..3528)
                     /gene="cvfB"
                     /locus_tag="VUR04_001894"
     CDS             complement(2674..3528)
                     /gene="cvfB"
                     /locus_tag="VUR04_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET5341734.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(3588..4145)
                     /gene="frr"
                     /locus_tag="VUR04_001895"
     CDS             complement(3588..4145)
                     /gene="frr"
                     /locus_tag="VUR04_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET5341735.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(4154..4891)
                     /locus_tag="VUR04_001896"
     CDS             complement(4154..4891)
                     /locus_tag="VUR04_001896"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET5341736.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(4975..6309)
                     /gene="trmFO"
                     /locus_tag="VUR04_001897"
     CDS             complement(4975..6309)
                     /gene="trmFO"
                     /locus_tag="VUR04_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET5341737.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(6554..6808)
                     /locus_tag="VUR04_001898"
     CDS             complement(6554..6808)
                     /locus_tag="VUR04_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET5341738.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            6803..>7196
                     /locus_tag="VUR04_001899"
     CDS             6803..>7196
                     /locus_tag="VUR04_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HET5341739.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKRISESF"
BASE COUNT         2067 a         1652 c         1349 g         2128 t
ORIGIN      
        1 aaggttactt gactagccta ccagttgctc aaggacttaa tcgtgactac actgatatca
       61 atgatttagt ataaattttg aaaagaaaag ggtgacttcg caagtcctac ccactgtgct
      121 ttgtgtcatc agctattaca tcgttggttt attgtactgt atactttgca actggagact
      181 ttcgttccag actcaattgt gcataagaaa ctctaaattg aataaagtca acagagtttc
      241 gcccaaccac ttcgtcttgt aatgacaatt atataaacca aaggaagctg agctctttag
      301 tcccagcttc tttttatata taaaatttta cccgtgcaaa gacagggcct tagcagactt
      361 cttttttact tcgttcaccc ttgctttttc tttttaggtt tgggcgttgg cagttggtta
      421 tacatagcta aaatcaggtc ttatagaaac atcttattat caagttcttc cactcaaatc
      481 atttctttgg cacctttgta tggaaactca aaagaagatt ggtcaatctt atctaagact
      541 gcttgcacgg gtttaactaa aagcgatcgt cataaatgcc gccaataatc ttgccgcgga
      601 agtaaagaat atactccccc atcatggaac ggtaagtcac atcatctaat cctgataatt
      661 gttccaaaac aaattccaaa tagttcttac ttgatgccat ttctaatctt ctaggctctg
      721 ttcaacgata acaaccgtat agagttcttg cttaacctcg catccaattg atttaaagcc
      781 ctgcttttcc caaaaatgct gagattgcgg atttccctta acataagcca aacgtgcctt
      841 tcgaaagttc ttagcaaaat aagctagtgc ttctgtcaca atatgactac caatcccttt
      901 cctctgatag gcttgatcaa ccataaacaa accaataaaa acagtctcct catcaggata
      961 tgcatagaca aaatccataa cagccacaag gtcaaatcca ttccaaaatc caacaaaaaa
     1021 cttatcagcc ttagctttac cttcaggtag acaaagcatg tcctctttta cagttgcaaa
     1081 atttggctct ggtggacaat gctgaaaata cagaggatta ctttcatata aagataaaat
     1141 acttggaata tccttttcag ttagtatcct acaactgtaa tacttagata gttggtcaat
     1201 catcttttca aattcctact ttcttgtgcc ctgtgattat gacacaggaa gatgcactga
     1261 tcgtcatcag ccacataaaa gttctttcca tcgtgcctaa tcgttgtctc aaacctttgg
     1321 ataaaacctt tagcctatac aactggattt tcctctctca aaagtatatt cttttgcagg
     1381 cgaacttcct caaaatcagt cgtgtgcaac ttcagtagaa tattcatagg ctcggataat
     1441 ctgagcgaca acaggatggc gaaccacatc cttggctgaa aaatgaacaa agtcaatctg
     1501 atggatgttc ttgagtttct cttgagcatc aatcaaaccg gacttgacat tacgtggcag
     1561 gtcaatctga ctaatatctc cattgacaat catcttagaa tgaaaaccta aacgagtcaa
     1621 gaacatcttc atctgcatga tggtcgtatt ttgcgcctca tcgagaatga caaaggcatc
     1681 atccaaggtc cgtccacgca tataggcaag gggcgcaatc tcgataattt cacgctccat
     1741 gagtcgagtt gtttggtctt tccccagaat ctgatacaag gcatcataaa caggtctaag
     1801 gtaaggatct accttctcct taagatcacc cggaagaaaa cctagactct ctcctgcttc
     1861 caccgctgga cgtgtcaaga taatccgctt gacttgccca cgtttaaggg cagtcactgc
     1921 caaagtaact gcaagaaagg tcttccccgt ccctgcaggc ccaattccaa aggtcacatc
     1981 atgctgtttg acactgtcca cataaagttt ttgacctaag gttttgacgc ggatcggttt
     2041 cccagtatta tctttgataa tttcttcttc gtaaagggcg acaaacttat caatttcatc
     2101 gtttttgacc atgctaattg cagtcaccac atctggcgta ccaacggtca tcccacggtt
     2161 caccaagacc atgagagctt gaataacctg acgggcttcc tcacaagcag actcttctcc
     2221 caaaacctgg acaatctccg tacgagcatg aatcaccaca tccagctctt cttccatcaa
     2281 acgaagatgg cgctcattgg aaccaaaaag atgaaacagg tcatctggat gactcagttg
     2341 aatgtctatt gaatgttcct tcaaataaag aacctctcta atccttttat ttctttttat
     2401 tatagcagag ggatggagaa attactagcc caaacccaat gaataaatgc tagtgttcta
     2461 gatattcctg ccaaatgctg tcaaaatctc ctaggttaaa agagaaactg gcatgctcct
     2521 ccaaaaagcg actgacctca tcaaaatcat ctgtatgttt tggaaaagct gcctcttcaa
     2581 aagcgaggtc tgccaaaatt gctttgggac tgttactttt aggattgcgc tcggtcatga
     2641 gccaagtgta aaatgatttt ctcataagcc tccctaaatc aactctgtac caaactggtc
     2701 ctgcttgatt ttaccagcct tcataagacc acctaaagct ttcttgaact gacctttaga
     2761 aatgccaaag gttgccttga tgtcgtctgg agatgacttg tcatttaagg tcatgaaacc
     2821 gccattgctt tccaaataag tcaaaatcat ctgagcatcg ttttccaaca tttcaaagga
     2881 gcgtggtttg agggagaggt tcaaagtgcg gtccacttca cggaaaccaa taacgcgcgc
     2941 atctaatact tgccccaaac gtggctctgc gtaacgctcg ctaggatgaa taaaaccaag
     3001 catattattt tctggtaggt aaacaaaagt tcctgacagc ttgagacggt aaacaatggc
     3061 tggccagttt tggttctgca tgttgttgta ggcaggacga gcgagacgtt ggaagtcttc
     3121 ttgataagcc aagaggcccc agatacggtc tttcttatcc acttcaagac ggatgtagag
     3181 ttggtcgccc ttcttaggcc agagttcctt gagctcaggg agaatatcga gtgacacaac
     3241 gatttccttg tcaggaaggc ctgtatccac aaagacaccc aagtccttac gaacctctgt
     3301 gacacgtccc caaccaaatt ggtcctgagt ggcagtcact tctaaggttg tcaggcggag
     3361 tttttgcttc atatccgtgt atgcaaaacc tttgaccgta tcccctactg tatgttggcc
     3421 ctcttcctta gcaagagcat aggtttgacc atccttttgc acaaagtaaa aacggtcatt
     3481 ttcatcgatg atcagtccaa cgataaaact tgcaagattt gtattcatat ttccttcttt
     3541 cgaataaaac tcagccagca atgccaactg agtttttctg tttattttta gacttccaaa
     3601 agttctttct ctttgttagc agtcatgtcg tcgatgtgtt taacagcatc gtctgttact
     3661 ttttgaatat ctttttcaag agtcttcaat tcgtcttcag tgatttcttt tgctttttct
     3721 tgtttcttag cttcgtccat agcatcgcga cggatattgc ggacagccac tttagcattt
     3781 tcgccgacct tcttcacttc tttagcaagg tcacgacgag tttcttctgt aagagctggg
     3841 ataaccaagc gaatcacaga accgtcatta gccggtgtga taccaagatc agaagcgttc
     3901 aaggcacgtt cgatgtcttt caatgaagac ttgtcaaatg gtgttaccaa caaaacacgc
     3961 gcttctggaa tcgtaattga agcgatttgg ttaagaggag tttcgactcc atagtattct
     4021 acatgtacac ggtcaagcaa gcttgcattg gcacgaccag cacggatacc accaaattca
     4081 cgagcaagtg attggtgaga ctgggtcatt ctctctttag ctttttcaat aattacgtta
     4141 gccatattct ttcttattcc ttttcttcga tattatttga aactgttgtt ccgatatttt
     4201 caccaaatac gacacgtttg atgttgcctg attggttcat gttgaagaca accaagtcaa
     4261 tgtcgttgtc cattgagagg gttgaggctg ttgagtccat gatacgaaga cctttgttga
     4321 taacatcacg gtgggtcaat tcttcaaact taacggctgt cttgtccttc ttaggatcgg
     4381 cattgtacac accatcgacg ccatttttag ccatgaggat ggcatctgct tcgatttcag
     4441 ctgcacgaag ggccgctgtt gtatctgtcg agaagtatgg tgaaccaatt ccagcaccaa
     4501 agataacgat acggcctttt tcaaggtgac gaagggcacg tccacggaca taaggctctg
     4561 ccacttgttg catagcaata gctgtttgta cacgcgtatc aaccccaact tgttgcaatg
     4621 aatctgccat cacaagagca ttcataacag tcccaagcat tccagtgtaa tctgcctgaa
     4681 cacggtccat acctgcttct gctgcaggtt ctccacgcca gagatttcct ccaccaataa
     4741 caagggcaat ttcgatacct aagctatgaa cttcttgaat ctcttttgcg attgtttgaa
     4801 ctgtttggat atcaatccct acgccacgtt caccggcaag ggcttcacct gataacttga
     4861 ttaaaatacg tttatacttg ggattcgcca ttttcactct ccttctttca tcctacctat
     4921 tttatcacaa tttctaagat ttttatagta tcatgaacaa ttctttcaaa aaaattagac
     4981 agtcaaaaat tcctctaagt cggcaagggc acgctctgca attttttcat aacgagcctt
     5041 cttatcacgg atacgctcgc cttccaactc cttgatgatc ccaaaattga cattcattgg
     5101 ttggaaatgt ttgctgtcgg catgggtaat gtaatgagct aagcttccaa tcgctgtcgt
     5161 ctcggggaaa ataacctcgc tttcttcctt gaagagacga gctgcgttaa ttcccgcaac
     5221 taagcccgaa gccgccgact caacatagcc ttccaccccc gtcatctgac cagcaaagaa
     5281 gagatttggt tgtttcttgg aacggtaagt ctgctcaaga agatttggtg aatccatgta
     5341 agaattgcga tgcatgacac cataacggac aaactccgca ttttcaagac ccggaatcat
     5401 ttggaagaca cgcttttgtt ctccccattt gaggtgggtc tggaaaccaa caatattgta
     5461 taggctacca gctgcattat cctgacgaag ttgcacaacc gcataaggtg ttttaaattc
     5521 tccatcacga ggtcctgtgt agtcgtccgg atactcaaga ccgactggct tcatagggcc
     5581 ataaagcata gttttaatgc cacgtttggc cataacttcg attggcatac atccttcaaa
     5641 gtacttttct ttttcaaaag aattgagcgg tgcttcttcc gcattgacca aggcttcatg
     5701 gaaatccata aactcttgct tggtcattgg agcattgaga taggctgctt ctcccttatc
     5761 ataacgagat ttgagataga ccttactcat atcgatagtg ttgacatcga taataggcgc
     5821 tgctgcatcg tagaaataga agccatcgcc attattaagg gcatgaatct tttcagccag
     5881 ggcatcgcta gtcaagggac cagtcgccac aactgtaata acatctgttg gcaattctgt
     5941 aatttcatca cgcaccactt caatcaaggg gtggttgacc actttttcgg tcaccatttg
     6001 agagaaacca tcacgatcca ccgcaagggc tccaccggca ggaacacgtg tagcctcagc
     6061 agattccaag ataacagaac ccaagcgacg catttcttcc ttgagaagac caactgcatt
     6121 tgtcaaagca tccccacgca aagaattgga acaaaccaac tcagcaaaat tgtctgtttt
     6181 atgctggggt gtagacttga caccacgcat ttcatatagt ttaactggaa taccacgctc
     6241 tgcgatttgg taagctgctt cagaacctgc caaaccagca ccgataacat tgatataaga
     6301 ttgagacacg acactaatac ctctttggga gtgtgaagtt aagattcaca ttgaaaaagc
     6361 caatcagact tacaagcttt cgagtttctt ggctcaggct gaaaaagtcc acagggcttt
     6421 ttcactccca caaatctttc tattttttct tctactagta taacaaaaaa agggaagaag
     6481 gcaaacttcc ctgtttagtc attttcttga tgtaaagaga tagtgagtat tccagttaag
     6541 aatcaattat atgctactct ataaaatctt ttccacataa cggatcgata gggactgtta
     6601 ttctatctct tgctataacc gtattatcta aaacagcata acattcaaca tagtgatctc
     6661 ctttaaactg tgaatcttcg tgatatttta ttttacctga aaaaatagca ccacgctcac
     6721 aatttcttct aatagcctca gcttcaatat ttcttacttt ccaatagact tcctgcgaaa
     6781 caaaatatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg
     6841 atttaagcgt cttgttggtg ttcagcgcac gacttttgaa gagatattag ctgtattaaa
     6901 aacagcttat caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga
     6961 ccttcttatg gccactcttc aatatgtgcg agaatatcga acttatgaac aaattgcggc
     7021 tgattttggt attcacgaaa gcaacttaat ccgtcggagc caatgggttg aagtaactct
     7081 tgttcaaagt ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat
     7141 tgatgcgacg gaagtacaaa tcaatcgccc taaaaaaaga attagcgaat cattct
//
LOCUS       DAVDFK010000063         7067 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.63, whole genome shotgun sequence.
ACCESSION   DAVDFK010000063 DAVDFK010000000
VERSION     DAVDFK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7067
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.63"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..499
                     /locus_tag="VUR04_001900"
                     /pseudo
     CDS             1..499
                     /locus_tag="VUR04_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            560..1522
                     /locus_tag="VUR04_001901"
     CDS             560..1522
                     /locus_tag="VUR04_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5341740.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFMKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1699..2706
                     /gene="gap"
                     /locus_tag="VUR04_001902"
     CDS             1699..2706
                     /gene="gap"
                     /locus_tag="VUR04_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET5341741.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2773..3609)
                     /locus_tag="VUR04_001903"
     CDS             complement(2773..3609)
                     /locus_tag="VUR04_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5341742.1"
                     /translation="MTVKQLLEEQLLIPRKIRYFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDTLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3735..5930
                     /locus_tag="VUR04_001904"
     CDS             3735..5930
                     /locus_tag="VUR04_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET5341743.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5983..6135
                     /gene="rpmG"
                     /locus_tag="VUR04_001905"
     CDS             5983..6135
                     /gene="rpmG"
                     /locus_tag="VUR04_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5341744.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6145..6321
                     /gene="secE"
                     /locus_tag="VUR04_001906"
     CDS             6145..6321
                     /gene="secE"
                     /locus_tag="VUR04_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET5341745.1"
                     /translation="MRFIGDIFKLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6376..6912
                     /gene="nusG"
                     /locus_tag="VUR04_001907"
     CDS             6376..6912
                     /gene="nusG"
                     /locus_tag="VUR04_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET5341746.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2207 a         1223 c         1530 g         2107 t
ORIGIN      
        1 agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgacga
       61 aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag gtcagttaat
      121 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
      181 tggtgagtta atcgttccaa tgacttacga agagacgatg acgagcgact tttttgaagt
      241 atggtttcag aagtttttct taccaacatt aaccacacca tcggttatta ttatagataa
      301 tgcaagattc catagaatgg ggaagctaga acttttatgc gaagagtttg ggcataaact
      361 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      421 caaaaagcac ctcaaaaggg tattaccaag ttgcaatacc ttttatgagg ctcttttgtc
      481 ttgttcttgt ttcaattgac tatagttcac ggatacagtt gggaaagaag ctattaaaca
      541 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaatgga
      601 tctgagtcaa acgatgcctt cttatgctca agtagtgagt ctttatgagg atacaagcat
      661 ttctgttagt agtaatgaga cggacaaagt gttggctgga tccctctata ctgatacaaa
      721 tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa
      781 aaatttgaca gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc
      841 tgccgaagct agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga
      901 agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa
      961 agaggctgga tttatgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca
     1021 gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca
     1081 gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct
     1141 ttcatcacaa gctattgtgg tagcagcggt tatgattggt attattattt acatcaatat
     1201 catgcaacgt tccaaggaaa taggtgtcat gaaagcagtt ggttatcaga atcgtgatgt
     1261 caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt
     1321 tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc
     1381 catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct
     1441 attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctgt
     1501 agaatcgtta cgctatgaat aataagggat tccttgattt acagtcttaa aaagaaactc
     1561 acatagaaaa acaatggcca tacttgcaat tcaactcaaa tagttgtata ataggtttgt
     1621 tgaaaggtga tttgtagtga ttcaagttac tcttttcaca ataaaaattt catgattttc
     1681 ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg acgtatcggt
     1741 cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg catcaacgac
     1801 cttacagatc cagttatgct tgcacacttg ttgaaatacg acacaactca aggtcgtttc
     1861 gacggtactg ttgaagttaa agaaggtgga tttgaagtta acggtaaatt catcaaagtt
     1921 tctgctgaac gtgatccaga acaaatcgac tgggctactg acggtgtaga aatcgttctt
     1981 gaagctactg gtttctttgc taagaaagaa gcagctgaaa aacaccttaa aggtggagct
     2041 aaaaaagttg ttatcactgc tcctggtgga aacgacgtta aaacagttgt attcaacact
     2101 aaccacaacg ttcttgacgg tactgaaaca gttatctcag gtgcttcatg tactacaaac
     2161 tgcttggctc caatggctaa agctcttcaa gacaactttg gtgttgttga aggattgatg
     2221 actactatcc acgcttacac tggtgaccaa atgatccttg acggaccaca ccgtggtggt
     2281 gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac tggtgctgca
     2341 aaagctatcg gtcttgtaat cccagaattg aatggtaaac ttgatggatc tgcacaacgc
     2401 gttccaactc caactggatc agttactgaa ttggtagcag ttcttgaaaa gaacgttact
     2461 gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg ttacacagaa
     2521 gatccaatcg tatcttcaga tatcgtaggt atgtcttacg gttcattgtt tgacgcaact
     2581 caaactaaag ttcttgacgt tgacggtaaa caattggtta aagttgtatc atggtacgac
     2641 aacgaaatgt catacactgc acaacttgtt cgtactcttg aatacttcgc aaaaattgct
     2701 aaataattct tgagttgata gaaagcaagg ctttgtggtc ttgcttttta tatggaaaaa
     2761 tggatgacac gatcatccat tcttttttaa ttctttttca aatgtatttg aaagggtagt
     2821 gaaagttagc ttctctaaag taagtgggtg ggtaaaggaa agtcggaagg catgaagcat
     2881 aagccggctt gtctttgatt tactattata gagagtgtct cccaggatag gaagattatg
     2941 atgcgaaagg tgcacacgaa tctgatgggt tcgccctgtc tttagcttgc aatgagccaa
     3001 ggaagtcttg tttgagaatt gctttaatct gcttacatgc gtttcagcat attgcccatt
     3061 ttttgcatca actattcttt ttctacgatc atggcgatca cgtccaattt tgtctctgaa
     3121 aacaagttct tttctgttga tatttccatc aactagagcc caatattctc tagaaatctc
     3181 ttttttctcc aataagcgat tgagaatggg caggataaaa ggatttttgg caaagagaac
     3241 taagccactg gtttccatgt ccagacgatg aacgacatag caggtttggc caacataggt
     3301 actgacatgg ttaagaaggg caatttcgtt tggttgatta ccatgcgttt tcatcccctc
     3361 tggtttgttt acaataatca agtgttgatc ttgataaact tcctgcacta agtctgggtt
     3421 gccccaaggg atcgtctttt gggaataatc ttcctcgtca aaagtcaact ggcaaacatc
     3481 tccaggattt acgatttcgt tccagtggac ttcttcttga tttatcaaaa tatgtttctt
     3541 gattctcaaa aaataacgga tttttctagg gatgaggagt tgttcctcaa gtaattgctt
     3601 taccgtcatt tgaggtagag aggcgggtaa tgtaaatgtg aattgcatac agatattgta
     3661 acaaaaaaag ccctatttgg ataggaaata gctaaattct tgtcttccta tgatgaagat
     3721 gataaaataa acgcatgaaa ttagataaat tatttgagaa atttctttct ctttttaaaa
     3781 aagaaacaag tgaactagag gactctgatt ctactatctt acgtcgctct cgtagtgatc
     3841 gaaaaaaatt agcccaagta ggtccgattc gaaaattctg gcgtcgttat catctaacaa
     3901 agattatcct tatactaggt ttgagtgcag gcttgctagt tggaatctat ttgtttgctg
     3961 tagccaagtc gaccaatgtc aatgatttgc aaaatgcctt gaaaactcgg actcttattt
     4021 ttgaccgtga agaaaaagag gctggtgcct tgtctggtca aaagggaacc tatgttgagc
     4081 tgactgacat cagtaaaaac ttgcagaatg ctgttattgc gacagaagac cgttctttct
     4141 ataaaaatga cgggattaac tatggccgtt tcttcttggc tattgtcact gctggacgtt
     4201 caggtggtgg ctctaccatt acccaacagc tggctaaaaa cgcctattta tcgcaggatc
     4261 aaactgttga gagaaaagcg aaagaatttt tccttgcctt agaattaagc aaaaaatata
     4321 gtaaggagca aattctaacc atgtacctta acaacgctta ttttggaaat ggtgtgtggg
     4381 gtgtagaaga tgcgagtaag aaatactttg gagtttctgc atcagaagtg agtctggatc
     4441 aagctgcgac tctggcaggg atgctcaagg ggccggaact gtataatccc ttgaattccg
     4501 tagaagattc tactaatcgg cgcgatactg tcttgaagaa tatggttgca gcaggatata
     4561 ttgataaaaa ccaagaaacc gaagctgctg aagttgatat gacttcgcaa ttgcacgata
     4621 agtatgaagg aaaaatctca gattaccgtt acccctctta ttttgatgcg gtggttaatg
     4681 aagctgtttc caagtataat ctaacagagg aagagattgt caataatggc taccgcattt
     4741 acacagagct ggaccaaaac taccaagcaa atatgcagat tgtttatgaa aacacatcgc
     4801 tatttccgag ggcagaggat ggaacgtttg ctcaatcagg aagtgtagct ctcgaaccga
     4861 aaacaggggg agttcgtgga gttgtcggtc aagttgctga caatgataaa actggattcc
     4921 ggaatttcaa ctatgcaacc caatcaaagc gtagtcctgg ttctacaatt aagcctttag
     4981 ttgtttatac gccagcagtt gaagcaggct gggctttgaa taagcagttg gataaccata
     5041 ccatgcagta tgacagctat aaggttgata actatgcagg gatcaaaacg agtcgagaag
     5101 ttcctatgta tcaagccttg gcagaatcgc ttaatctacc tgctgttgcc actgttaatg
     5161 atttgggtgt cgacaaggct tttgaggcag gcgaaaaatt cggactcaac atggaaaagg
     5221 tcgaccgtgt tcttggtgtc gccttgggaa gcggtgttga aaccaaccct cttcaaatgg
     5281 ctcaagcata cgccgccttt gcaaatgaag gtttaatgcc tgaagctcat tttattagta
     5341 gaattgaaaa tgctagtgga caagttattg cgagtcataa aaattcacaa aaacgggtga
     5401 ttgataagtc tgtagctgac aagatgacca gtatgatgtt ggggactttc accaacggta
     5461 ccggtattag ttcatcgcct gcagactatg tcatggcagg gaaaactgga acaactgaag
     5521 cagttttcaa tccggagtac acaagtgacc agtgggtaat tggttatact ccggatgtag
     5581 tgattagcca ctggcttggc tttccgacca ctgatgaaaa ccactatcta gctggctcta
     5641 cttcaaacgg tgcagctcat gtctttagaa acattgccaa taccatttta ccttatacgc
     5701 caggaagtac ctttacggtt gaaaatgctt ataagcaaaa tggaattgca ccagccaata
     5761 caaaaagaca agtacaaacc aatgataata gccagacaga tgataatttg tctgatattc
     5821 gagggcgtgc gcaaagtcta gtagatgagg ctagccgggc tatctcagat gcgaagatta
     5881 aggaaaaggc tcaaacaata tgggattcga tagtcaatct atttcgctaa gatgcttgtc
     5941 aaagcctagc tttcttgtta taatggataa gatggaggcg ttatggcact aaaaaaagca
     6001 agcctagctt gtgcggtttg tggttcgaga aactattcaa tcaagatcag cggaaacccc
     6061 aagcctacac gactagaagt aaataaattt tgtaagcatt gtggcaagta cactacacac
     6121 agagaaacga gataggagag agcgatgcgt tttattggag atatttttaa acttcttaaa
     6181 gacacaacat ggccaactcg caaggaaagc tggagagatt ttcgttctat catggaatac
     6241 acagctttct ttgtagtaat tatttacatt tttgaccagt tgattgtttc aggtttgatt
     6301 cgatttatta acatttttta gaagattagt ggagttaatt acactagaaa tcttctattt
     6361 atgaaaggaa atatcatgga tagttttgat aaaggatggt ttgttttaca aacttattct
     6421 ggttatgaaa ataaggtgaa agaaaatcta ttacaacgtg cacaaaccta caatatgttg
     6481 gataatattc tacgcgttga aattccaaca caaacagtgc aagttgaaaa aaatggaaag
     6541 agaaaagaag tagaagaaaa tcgctttcca ggttatgttc ttgtagaaat ggtcatgaca
     6601 gatgaagctt ggtttgttgt tcgaaacaca ccaaatgtta caggatttgt cggatcacac
     6661 gggaacagat caaaaccaac tccattattg gaacaagaaa ttcgtgacat tttggtatct
     6721 atgggacaaa ctgttcaaga atttgatttc gatgttgaga ttggtcaaac tgtacgtatt
     6781 attgatggtg cttttgcaga ctacactggt aagattacag aaattgataa taacaaagtg
     6841 aaaatgatta tctctatgtt tggtaatgac acagttgcag aagtaaacct aaaccaaatc
     6901 gcagaattat aaccctgaga gaggctggag cctctctttt ttgtgcagtt taggagctaa
     6961 agggaacaga atggagaaaa tggaacaaat gtgttttcta atctgttaga ctgtatctag
     7021 aaaggggaaa attatgatta aagaattgta tgaagaagtc caaggga
//
LOCUS       DAVDFK010000064         6990 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.64, whole genome shotgun sequence.
ACCESSION   DAVDFK010000064 DAVDFK010000000
VERSION     DAVDFK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.64"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(93..323)
                     /locus_tag="VUR04_001908"
     CDS             complement(93..323)
                     /locus_tag="VUR04_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341747.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(341..982)
                     /locus_tag="VUR04_001909"
     CDS             complement(341..982)
                     /locus_tag="VUR04_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5341748.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAVVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(994..1728)
                     /locus_tag="VUR04_001910"
     CDS             complement(994..1728)
                     /locus_tag="VUR04_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET5341749.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1731..1928)
                     /locus_tag="VUR04_001911"
     CDS             complement(1731..1928)
                     /locus_tag="VUR04_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341750.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(1928..2134)
                     /locus_tag="VUR04_001912"
     CDS             complement(1928..2134)
                     /locus_tag="VUR04_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341751.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2144..2458)
                     /locus_tag="VUR04_001913"
     CDS             complement(2144..2458)
                     /locus_tag="VUR04_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341752.1"
                     /translation="MWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKKPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2713..4002)
                     /locus_tag="VUR04_001914"
     CDS             complement(2713..4002)
                     /locus_tag="VUR04_001914"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET5341753.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4080..5327)
                     /locus_tag="VUR04_001915"
     CDS             complement(4080..5327)
                     /locus_tag="VUR04_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET5341754.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFFKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLAHTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5518..6369)
                     /gene="rgg"
                     /locus_tag="VUR04_001916"
     CDS             complement(5518..6369)
                     /gene="rgg"
                     /locus_tag="VUR04_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET5341755.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6493..6834
                     /locus_tag="VUR04_001917"
     CDS             6493..6834
                     /locus_tag="VUR04_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET5341756.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2264 a         1452 c         1283 g         1991 t
ORIGIN      
        1 gtgttttgag caacctgcgg ttagcttcct agtttgctct ttgattttca ttgagtataa
       61 tacaaaaatc cgatgaactt caccggactc ttttattttg aatttttgcc tgctttacgc
      121 ttttcagcga tttcggctgc ctttcgaggc aagacaattt ccgttatgta agccgtccca
      181 aaacgcagta cacctgcaat aggagcaaag acaactgcta gatagttata gaagaaatcg
      241 cctttgaagg cataagctag cgctccaatg atgaaaaata gaacgactgc ctgaatcact
      301 gctaataaaa ttactcgttt catgtgacct cctgactcta ttatagcatg agaatcatca
      361 aaaagccgac taaattattc aaagcgtgaa gagaaatact gtagaccaga ccttttctgc
      421 taatgtaagc caaacccaaa ctaaaaccaa ggctaaaata gacaaaaaat tgttgcacat
      481 cacctggaaa atgaatcaag gcaaatagaa gactagatac cagaagaaaa atcagggttc
      541 gtttactatt gtcctgctta ggaaagagat agcgtgctaa catccctcta aaaacaatct
      601 cttccgtcaa aggagcaaaa ataaccacag caaagaatga gaaaagtggt tgagacaagg
      661 tcaagtctgt cgctatttgc tgatttactg aaggatcatc tggcaagaag aattgaacga
      721 ccagagataa gaaccaaacc aagacaggaa gccaaataaa tcggttaaag ccgctcttct
      781 caatatgaac aggagccttc tgataccatt tgtaaatgcc gtacacatat actacagcca
      841 aggccacata gagtagagta acagcatagg gtgaagcgcc taaagcaagc gacgcagtcg
      901 cgagcccctg aataaagcca tagataaata aaaaggatag aagggctaga agaatccagc
      961 caaggttttt aagtaatttc atagataact cctttatttg aaataacgtt ttaccatagg
     1021 taactgcatc acattgatat aaacatggat ggctcctaca agcaagaaag ctagtaactg
     1081 aatctctcct gtcaagaaag aaatgataat aagaaaaata tataaggctg gtaagacata
     1141 ttggtgtaat tggaataaaa ttcgaaaact ctgttccaaa ttagcctgac gctccccttc
     1201 atcataagaa tttatatagt tcaagacatc ctttggtgta gcgaaaaatt ccaaatcaaa
     1261 ctgacgaaca atcgcaatgg ttttaaaaag agatttttga gcgactaaga ataccacaaa
     1321 gagtaagaaa gaaaggaaaa atgtttgagg gtttgtatgc aatataatca cctcacttaa
     1381 tgaaataaaa atagccaatg gaatcgctac acctgtaata ttaaaagcaa tggttccaaa
     1441 ctcaagattc cgatacattt gcacataata ggtttcattc agatcgtcat ccatttcctc
     1501 ttgatacaag gaatgaaatt ttctgctttt ctttaagaaa ttgaaagtca aaaacatact
     1561 aatgaaacct atcagtaaac aaatagctga tatccatggc atcaaggctt ttacatctaa
     1621 aataatttcg tgggattcga cacgtgcctt aaacatccct acaaacatgc ccaagaaccc
     1681 ccccaagaca atagacatca aaaataacaa tctacgtttc tttttcatat tcattctcct
     1741 ttttcacttg ctagattttt ggatttcttt tcaatccatt caattactgg gatgagagca
     1801 aagtagaccc aaacaaattg gtcgctttga tagggattaa accagcttag gtccatccca
     1861 atcagtagaa atacgctgac taataaagct atgaccacta cataataaat cactttatac
     1921 ttgttcatca ctcgtcctcc tccaaacgaa ataccgattc gactgtttcg ttgaaaattt
     1981 gagatatttt cagggcaatg ataatggatg gggtgtactc atcccgttct agtaggctaa
     2041 tggtctgtct ggaaacccct gccagtttgg ctaggtcggt ttgattgaga ccatcgcgag
     2101 ctcgaagctc ttttagacga ttttttagtt gcacgttaca cacctactct ccgtcaaatt
     2161 caacggtttg gatatcttca atacgttgca acttgaattt ttcttttccc gtattatcta
     2221 cacgtcgtag ctttacccat tcctcatcaa catccacaac ttcccagtta tctggcccaa
     2281 tatacactcc cgttataatt ggtttctttc caatcatttc ttgcaataat ctcgacattt
     2341 ctgcgtttcc tttctctttt cgctcaagtt ttttgatttt attctctagt ttcttgattt
     2401 ttttagaatt attagaataa aagaaaataa taaatagtat aaatactagt acccacatca
     2461 tagctccttt cttcttttct cttaacttgc ttacattgta acacgtcttt ttctttttga
     2521 caagtatagc tgtcaaaaag tttatgattt ttgtcatttt gcaaaagaaa aaggtcagga
     2581 gtaagttcct gaccacttta tctatcatta atactcttct aaaatctctt caaaccacgt
     2641 cagtttcatc tacaacctca aaaccatgtt ttgagcaacc tgcggctagc ttcctagttt
     2701 gctctttgat tttcattgag tataaaatcc tagtttttca aagatttctg agaagttttg
     2761 gctgattgtc tcaagtgaca cttgcacttc ttctcgggtt tggttgttct tgactgtcac
     2821 ttgtctgctt tcgacttcgc tctctcctag ggtgatgagg gtcttagccg caaagacatc
     2881 ggctgacttg aactgagctt tgagcttacg gttgaggtaa tcacgctctg ctttgaaacc
     2941 ttgttggcga agagcttgga ctagttctag ggctttgaca tttgctccat cacccaagac
     3001 tgcgatatag acatctaggg cattttcgat agggagggcc acgccttgtt tttcaaggat
     3061 gagaagcagg cgctctacac caagcccaaa accaaatcca gcagtttcag ggcctccaaa
     3121 gtaagcaacc aaaccatcgt agcgaccacc cgcacagact gtcaagtcat tgccctcaat
     3181 ctctgtgata aactcgaaaa tggtgtggtt gtagtagtcc agaccacgta ccatattggt
     3241 atcgatgatg taatctactc caagattttc caacatctga cgcacagcat caaaatgagt
     3301 ttggctttct tcatcaagaa agtccaagat agacggcgca ttctctactg ccaccttgtc
     3361 ttctttttcc ttagagtcca agacacgaag aggattttcc tccaagcgac gttggctatc
     3421 cttagacaag gtctccttga gcggtgtcaa atagtcaatc aaggcttggc ggtaggctgc
     3481 acggctctca ggatttccaa gagtgttgag gtgcaatttg acaccttgaa taccgatttc
     3541 cttcaaaaaa tgggctgcca tagcgattgt ttccacatcg gtagctggat tgctagagcc
     3601 aaaacactca acaccaatct ggtggaattg gcgcaagcgc cctgcctgtg gacgctcata
     3661 acggaacata ggtcccatat agtagaactt gcttggcttt tgcacttctg gggcgaaaag
     3721 tttattttcc acataggaac ggacaacggg tgcagttcct tctggacgga gggtaatatg
     3781 acggtcaccc ttgtcataaa aatcgtacat ttccttggtt acgatatccg ttgtatctcc
     3841 gacagagcga ctgataacct cgtaatgctc aaaaataggc gtgcgcactt ctgcgtagtt
     3901 gtagcgtttg aaaatttcac gggcaaagcc ctcaacgtac tgccacttgg cagattcagc
     3961 aggtaaaata tcctgcgttc cttttggttt ttgtaatttc atagggaatc ctctttaaac
     4021 ttaatagtct tattttacca caaataaagg gattaaaaca gtgagaaaaa aattaggatt
     4081 tagatatcat ttttgagatt aagaattgtc aaaaaaatag ctagcaagga aagaccaaca
     4141 aatagcatcc aagtcaactg tatattccat acggctacta gtgaaaaaca agctgttccc
     4201 acaggtatgg ataaggtaaa caatagacct aaaaaattac tagtatgagc tagaacctct
     4261 ggagctagat ttttcatgag catggcacta atctttggtt gaactttacc agacacatac
     4321 agagtaaaga agagaaatag caaaccaagc acgacttgat tgaataaatt agccaaacca
     4381 actagactaa gtcctacggt cgcccacatc atcaatctag gcaaggactg cttcccaaaa
     4441 taatcattgc ccgtaaggct actgatgatg attgctacta aaacacagaa ttgattgata
     4501 aatagtgcct ctgtataaga aaaattcaag agagaatggc tcaaaaagaa gatattataa
     4561 attccaccca aagcgccacc caaggaatta ataagcaaga cagcaaagag cataaaacca
     4621 aagtttttct gtccactttt aaaaaaaacg agacgtaaat ttcggtaaat tgttaggaac
     4681 tggtctttga tagaaagctt ctcatttttt aagttttcac catcagcaga tgacattgac
     4741 aggctcaatt tgctttttcc taaaaagagg atagtggctg atactaggaa aaagcaggca
     4801 ttgattcccg caacgagaga aaaattgttg accgatagag ctaagagcca gactccgaaa
     4861 gcttgaccac caatagctga aatataggtg atgaactgtg aaaaagaata agcctccatc
     4921 agatcatctt cagctacttt ttccttaata agaggcatgc gcaagccacc tgcaaaatca
     4981 ctgatgacat cactaatgac attgatcaaa cacaggctag aaaaggcaaa gagactagct
     5041 tgctgaacaa ctagggctgc tagaaaaaat agaaccgcct gaaacaaacc gctatagacc
     5101 atccatttga ccttgtccct cgtgtaatct gcccgaatcc ctacaaaaac tgtaaagaag
     5161 gtcggaagaa tcatgacaat attcgccata gcaacagcaa aagatgcttg tgacaaggtc
     5221 gatgcataga cgataaagac caggttgaaa atcgaagcac caaaagcatt gaagaagcgt
     5281 gataaagtca aaattctata agctggattt ctaaacaata gtttcataga taatctccct
     5341 ccttgttcta agttctacat caagaatagc tttagtatag cacttatgaa tttgcgaaac
     5401 gattcttttg aatatatgca acaaataaaa tgagcaaaaa aacgatagaa cttttgtaat
     5461 gacctgagag agggcaatag ttctatcgct tcaaattttt tcttggtttg cagatattca
     5521 acattcggtc gtatttctat agtattcggc agatttatta cagccaagca tctcaaaaat
     5581 acggacagca tcctccatct ttttctgacc ttccttgact ctaccttgct tgctatcaag
     5641 gagaccttct gcccacagat aaacaattcg gaaataggtc tcattttcct tgtagaaatg
     5701 ctcttcgata acacgtttaa aataataggc attggtaaat tcttcacact caatactagc
     5761 taaaaagcca ttcaatagta tagtataaaa aaggtttcga ttgccagaca tttccattag
     5821 aaaatcggat ttacgtacca tttctcgtac atatctagta aaaagagaaa cagataaaaa
     5881 tggagaactg actgaaaata aattgagttc atagattccc cagatctcgg tagaaaacaa
     5941 ataatcatga aggacttttc cttcctctgc tgttaactct accctttcat ccatgctctt
     6001 catataagac ttgatcataa tggcatttag aatatgtttc tgtttgttgt gagaatgggc
     6061 atgcttttga tactccctgc gatataagtc ctcaagaggt gctacattct ttggttccaa
     6121 gacatctgta atttcttttc tcaactcaga atctgtatca tactggaaac ctctcgccag
     6181 aaagaggatc tcctccacac tggcagatat attttccaga gcaaatagaa acttttccac
     6241 cgaaagctca ctctgacctg tttcaaaacg ggacaacata gacggcgaaa attgtcctcc
     6301 ggttgcttgt ctcagtgaga tatttcttga ctctcgtaat tgtctaaaga cttttccaat
     6361 ctgctccata gacttcccct tgattccgta ttttcttcat tttatcatat ttttcagaaa
     6421 attcatcaaa aacttgccaa attgtcagaa ttatgagaaa atagaggata tttatcacgt
     6481 ggagggactg ctatgagaga cgatatcaaa atcaatgacc gtgctttggc cttgcaagac
     6541 caaattatcg aaaaactaga gaaagttttt gatacagatg tggaattgga tgtttacaat
     6601 ctaggtctga tttatgaaat caatctggat gaaacggggc tctgcaagat tgtcatgacc
     6661 ttcaccgata ctgcctgtga ttgcgccgaa agcctgccta ttgaaatcgt ggcaggtctg
     6721 aaacaaatcg agggtatcga agatatcaag gttgaagtta cctggtcgcc tgcttggaaa
     6781 atcacacgaa tcagtcgcta tggccgtatt gcccttggac taccacctcg ttaagcaggc
     6841 caatcacttt taaagatgaa aaaagcaagc cgaaaatggc ttgctttttg atactcaatg
     6901 aaaatcaaag ggcaaactag aaaactagcc gcaggttgct caaaacactg ttttgaagtt
     6961 atggatagaa ctgacgaagt cagctcaaaa
//
LOCUS       DAVDFK010000065         6684 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.65, whole genome shotgun sequence.
ACCESSION   DAVDFK010000065 DAVDFK010000000
VERSION     DAVDFK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.65"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(123..406)
                     /locus_tag="VUR04_001918"
                     /pseudo
     CDS             complement(123..406)
                     /locus_tag="VUR04_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(396..557)
                     /locus_tag="VUR04_001919"
     CDS             complement(396..557)
                     /locus_tag="VUR04_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET5341757.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            627..1391
                     /locus_tag="VUR04_001920"
     CDS             627..1391
                     /locus_tag="VUR04_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET5341758.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKAYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHYL"
     gene            2001..3380
                     /locus_tag="VUR04_001921"
     CDS             2001..3380
                     /locus_tag="VUR04_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET5341759.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLITFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTLGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3394..4059
                     /locus_tag="VUR04_001922"
     CDS             3394..4059
                     /locus_tag="VUR04_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET5341760.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNMNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4459..4998
                     /locus_tag="VUR04_001923"
     CDS             4459..4998
                     /locus_tag="VUR04_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5341761.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQKNKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LEILQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTALLRASQF"
     gene            5065..5475
                     /locus_tag="VUR04_001924"
     CDS             5065..5475
                     /locus_tag="VUR04_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET5341762.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5591..>6684
                     /gene="pavB"
                     /locus_tag="VUR04_001925"
     CDS             5591..>6684
                     /gene="pavB"
                     /locus_tag="VUR04_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET5341763.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEEASGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNG"
BASE COUNT         1818 a         1283 c         1545 g         2038 t
ORIGIN      
        1 atccacaacc ttaaaacagt gttttgagca gcctgcggct aacttcctag tttgcacttt
       61 gattttcatt gagtattact tcatcttttc ctgaaattga gtttttgccc aactcctctt
      121 gattattcta cttgaccggg ccaagcattc ataccacctt ctacgttggt aacggtgagg
      181 ccttgggagc tgagaaactg gcaggtagat gcagagcgga ctcctccgtg acaaatgaca
      241 tagtattcat ggtcaggttt gagttctttg tagccttgct ctaaggtatt tatggaagat
      301 ttttgggtcc tgcttggaat tcatgtgctt cacggacatc gataagttcc agattttcat
      361 tttgatattt tccataaaag tcagccatgc tgatactagt ttccatattc tactccttct
      421 gggttagcca ttttgtatag tgaataagcg ccgtcaaggt tttggacggt aaatcctgct
      481 tgcttgagga taggctctgc gatatagcta cgcaaaccac tgtggcagct gacgatgtag
      541 gcttgttttt tgtccagttc atcagcttcc tccttgacac tcggtcagat tttgatacaa
      601 tagtacaaaa ttagaggagg tgggctatga ttcagaaaca tgcgattccc attttagagt
      661 ttgatgataa tcctcaggcg gttatcatgc ccaatcacga ggggttggat ttgcagttgc
      721 caaagaagtg tgtctatgct tttttaggtg aggagattga ccgctatgcg agggaagtag
      781 gggcgaactg tgttggcgaa tttgtttctg ccaccaaggc ctatccagtt tatgtcgtga
      841 actacaagga cgaggagatt tgtctggttc aggctcctgt cggttcagct ccagcagccc
      901 agtttatgga ttggttgatt ggctatggtg tggagcagat tatctctact gggacctgtg
      961 gtgtcctagc tgatatagag gaaaatgcct ttctagtccc tgttcgcgct ctgcgagatg
     1021 aaggagccag ttaccactat gtggcacctt ctcgttatat ggaaatgcag ccagaggcta
     1081 ttgctgccat tgagcgagtt ttggatgata gagggattcc ttatgaagaa gtcatgacct
     1141 ggtccacaga tggtttttac cgagaaacgg ctgaaaaggt ggcttatcgc aaggaagaag
     1201 actgtgctgt tgtggagatg gagtgttccg ctcttgcggc agtagctcaa ttgcgtgggg
     1261 ttctctgggg tgaattgttg ttcacagcag attctctagc ggacttggac cagtacgaca
     1321 gtcgtgactg gggctcggaa gcttttaata aggcgctaga actgagttta gcaagtgttc
     1381 actaccttta gttgtactgg caaaggattt gttttatcat aaaatgtcta gctcatactt
     1441 ttcaaaaata tgtttaaacg aggtcacctt cctcttgtcc taggcatgtt gaggttggga
     1501 aaaatcttta aaatcagaaa aacgtatcat atcaggtgat gaaaactttg atactatgcg
     1561 ttttatgttg gtaagattta gagtgagatg aaatgatact cttcgaaaat ctcttcaaac
     1621 caggtcagct tcaccttgcc gtatagatgt tactgacttc gtcagttcta tctgcaacct
     1681 caaaacagtg ttttgagctg acttcgtcag ttctatccac aacctcaaaa cagtgttttg
     1741 agcaacctgt gactagcttt ctaagcgatg ccttggttct cattgcctat aatcaaaaag
     1801 agaaattttc tcctgaaaag catatagagt agctggcgtt aaaagctcct gtcttgcttt
     1861 tttgacctat agtcacatct atcaagtatt gttcttgcct aagctatcaa taaaaaggtg
     1921 gcatttttta ggcttggtgt tagtgaattt tgccttatcc tatctaagtc atttcgagct
     1981 ttttatggta caatggaaac atgttattca aattatctaa ggaaaaaata gagctaggct
     2041 tatctcgttt atcgccagcc cgtcgtattt ttttgagttt tgccttggtc attttactag
     2101 gctctcttct tttgagcttg ccctttgtcc aagttgaaag ctcacgagcg acttattttg
     2161 atcatctttt cactgctgtc tctgcagtct gtgtgacagg tctctcaacc cttccagtag
     2221 ctcacaccta taatatatgg ggccaaataa tctgtttgct cttgattcag atcggtggtc
     2281 tagggctcat aacctttatt ggggttttct atatccagag caagcaaaag cttagtcttc
     2341 gtagccgtgc aactattcag gatagtttta gttatggaga aactcgatct ttgagaaagt
     2401 ttgtctattc tatttttctc acgacctttt tggttgagag cttgggagct attttgctta
     2461 gttttcgcct tattcctcaa cttggctggg gacgtggtct ttttagttcc atttttctag
     2521 cgatctcagc cttctgtaat gccggttttg ataatttagg gagcaccagt ttatttgctt
     2581 ttcagaccga tttactggtc aatctggtga ttgcaggctt gattattaca ggcggccttg
     2641 gttttatggt ctggtttgat ttggctggtc atgtaggaag aaagaaaaaa ggacgtctgc
     2701 actttcatac gaagcttgta ctattattga ctctaggttt gttgttattt ggaacggcaa
     2761 ctactctctt tcttgagtgg aacaatgctg gaacgattgg caatctccct gttgccgata
     2821 aggttttagt tagctttttt caaacagtga cgatgcgaac agctggcttt tctacgatag
     2881 attatactca ggctcatcct gtgactcttt tgatttatat cttacagatg tttctaggtg
     2941 gggcacctgg aggaacagct gggggactca agattacgac attttttgtc ctcttggtct
     3001 ttgcacgaag tgagcttcta ggcttgcctc atgccaatgt tgcgagacga acgattgcgc
     3061 cgcgaacggt tcaaaaatcc tttagtgtct ttattatctt tttgatgagc ttcttgatag
     3121 gattgattct gctagggata acagccaaag gcaatcctcc ctttatccac ctcatatttg
     3181 aaaccatttc agctcttagt acagttggtg taacggcaaa tctgactcct gaccttggga
     3241 aattggctct cagtgttatc atgccactta tgtttatggg acgaattggt cccttgacct
     3301 tgtttgttag cttggcagat taccatccag aaaagaaaga tatgattcac tatatgaaag
     3361 cagatattag tattggttaa gaaaggaaag agcatgtcag atcgtacgat tggaattttg
     3421 ggcttgggaa tttttgggag cagtgtccta gctgccctag ccaagcagga tatgaatatt
     3481 atcgctattg atgaccacgc agagcgcatc aatcagtttg agccagtttt ggcgcgtgga
     3541 gtgattggtg acatcacaga tgaagaatta ttgagatcag cagggattga tacctgcgat
     3601 accgttgtag tcgcgacagg tgaaaatctg gagtcgagtg tgcttgcggt tatgcactgt
     3661 aagagtttgg gggtaccgac tgttattgct aaggtcaaaa gtcagaccgc taagaaagtg
     3721 ctagaaaaga ttggagctga ctcggttatc tcgccagagt atgaaatggg gcagtctcta
     3781 gcacagacca ttcttttcca taatagtgtt gatgtctttc agttggataa aaatgtgtct
     3841 atcgtggaga tgaaaattcc tcagtcttgg gcaggtcaaa gtctgagtaa attagacctc
     3901 cgtggcaaat acaatatgaa tattttgggt ttccgagagc aggaaaattc cccattggat
     3961 gttgaatttg gaccagatga cctcttgaaa gcagatacct atattttggc agtcatcaac
     4021 aaccagtatt tggataccct agtagcattg aattcgtaaa gagggatgac ccctcttttt
     4081 tgatgcccaa gatggcaaat agagacagaa gccccttgtc ttctagtaaa agttcttcaa
     4141 aggctggact ttatggtaaa atagaaggaa gtgacaagag agagtaatac tcaatgaaaa
     4201 tcaaagatca aactaggaaa ctagctgcgg gctgctcaaa acactgtttt gaggttgtgg
     4261 atagaactga cgaagtcagc tcaaaacact gttttgaagt tgcagataga actgacgaag
     4321 tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata
     4381 cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa gagtataaga aaaaatcagt
     4441 cccctaaagg agcagattat gaagttattg tctatcgcca tttctagcta taatgcagca
     4501 gcctatcttc attactgtgt ggagtcgcta gtgattggtg gtgagcaagt tgggattttg
     4561 attatcaatg acgggtctca ggatcagact caggaaatcg ctgagtgttt agctagcaag
     4621 tatcctaata tcgttagagc catctatcag aaaaataaat gccatggcgg tgcggtcaat
     4681 cgtggcttgg cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg
     4741 gatcctcgtg cctacttgaa aattcttgaa atcttgcagg aacttgagag caagggtcaa
     4801 gaggtggatg tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag
     4861 agtatgagtt acgattcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga
     4921 aatttctcca aaggccagta taccatgatg cactcgctga tttatcggac agctttgttg
     4981 cgtgctagcc agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt
     5041 acgccccttc agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg
     5101 attgggcgtg aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa
     5161 ctcaaggtca atcgactctt ggtagaccag cttgatttgt cccaagtgag tcatcccaaa
     5221 atgcgagaat atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc
     5281 aaccgatctg aaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag
     5341 cagaaaaatc cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa
     5401 cattctgtct tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt
     5461 tatggattta attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt
     5521 cttagtcctt tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa
     5581 ggagaatcct atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct
     5641 cagtgtcggt gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc
     5701 aagttctgta cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagaggc
     5761 atcgggaacg aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc
     5821 gaaacctgag ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga
     5881 agtgagcgag gaaacaaact cttctagttt ggatacactt tttgaaaaag atgaagaagc
     5941 tcaagaaaat ccagagctaa cagatgcctt aaaagaaact gtagatacag ctgatgtgga
     6001 tgggacacaa gcaagcccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga
     6061 aaatacaaaa gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg
     6121 tcctttcact gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat
     6181 gttaactcgt ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc
     6241 taaaaatcct gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt
     6301 agacttaaat ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc
     6361 taatggtact caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc
     6421 tgacttgact aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc
     6481 taaagaaact gtcgaaaaag ctgttaaaga taacgttaaa gacagtatcg atgttccagc
     6541 agcctaccta gaaaaggcca agggtgaagg tccattcaca gcaggtgtca accatgtgat
     6601 tccatacgaa ctcttcgcag gtgatggtat gttgactcgt ctcttgctca aggcatctga
     6661 caaggcacca tggtcagata acgg
//
LOCUS       DAVDFK010000066         6543 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.66, whole genome shotgun sequence.
ACCESSION   DAVDFK010000066 DAVDFK010000000
VERSION     DAVDFK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6543
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.66"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(370..1362)
                     /locus_tag="VUR04_001926"
     CDS             complement(370..1362)
                     /locus_tag="VUR04_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341764.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1522..3276
                     /locus_tag="VUR04_001927"
     CDS             1522..3276
                     /locus_tag="VUR04_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341765.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISTLLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3260..4981
                     /locus_tag="VUR04_001928"
     CDS             3260..4981
                     /locus_tag="VUR04_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341766.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVKGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDTKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            4992..5621
                     /locus_tag="VUR04_001929"
     CDS             4992..5621
                     /locus_tag="VUR04_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET5341767.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            5522..6080
                     /locus_tag="VUR04_001930"
                     /pseudo
     CDS             5522..6080
                     /locus_tag="VUR04_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            6068..>6543
                     /locus_tag="VUR04_001931"
     CDS             6068..>6543
                     /locus_tag="VUR04_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341768.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGKIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGT"
BASE COUNT         2332 a          903 c         1144 g         2164 t
ORIGIN      
        1 ataatatcac taaatccacc taattatagg acgttttcag atttttagtc ccgtcccagt
       61 cccagtaccg gagaaatatt gttttaatat aatatctctt tttgtcttct aagctcttaa
      121 aagcaaaaga acaagtaaag agtcaagaca aggataaaaa gtccatatta gggcaaataa
      181 aaagctttaa gacagatgac aaatctaagt caaataagaa agaccatagc aaaggtgcag
      241 agagataaat attggcggtc ttcggactgc ctttattttt ttatccattt ttcaaatcaa
      301 atttattcag actatatatg cacatataca cttaaattca tataaaaaca tggcttgtaa
      361 aaaattactt taatcacaat aatcgcattt aaaattgtga tgtttgcaag ctaaattacg
      421 gacttcactt ggaagttttc ccttgtatct tttataatag atagaaaatt tgctggcaga
      481 tgaatatcca acagattctg ctatctcttt tataggtagt tcagtgttta aaagaagagt
      541 ttcagctaca ttcattcttt ttctttgagt gtactctgta atgctttgac aatatttttc
      601 cttaaataaa ttttttaatt tagtaccact cattttagat attttttcaa gcgtgccttg
      661 atttacattc gttgcaaaat gatcatctaa gaatcttgct acatcttcaa gtgctttatc
      721 atcatcaatt tcaattttat atttttttct atttaagtat gtgtcaatta ctatacttat
      781 ccattcattt gcctttgctt taaagaaaaa atcagcggca ggagcgtcca tcttacaatt
      841 taatatttcc attgccactc tttctaaggc ctttgtaagt attatttgat tcggttgaag
      901 caaggttgaa taaaaagatt ctggattaat gttaatagat gctaaatgtt tttctattag
      961 ctctttttta aaaccaatgg aaacagcaag ataacaacaa ttctcgtgta ataaaaaaac
     1021 aaaatcatct tttatattat caaaatcaaa agtacataaa gagtttgcgg taatagtttg
     1081 atacggatta aacttttctc cgtttgcact gacaatgtaa cttgaataaa ttgaaacata
     1141 gtctgacata ctataagtgc tattttgaac tacttcctct ttgatataaa aatcatgtat
     1201 atcgataatg aagctgcctc cttcataaaa ccaatatagg ccttctgcat aagttgaatt
     1261 ctcttttttc caacaaaatg tatgacctgc acttgaatac ttctcattgt ttttacattc
     1321 atctactttc atataatctt ttacaaaatc ataatatgac ataacacact atccctttta
     1381 gacaatattc caattagcct tattaattca aaactattgt attagtaatt ataacagatg
     1441 tataatagaa aagcaatgat agatattatc aattaagcga atttatatct aaaagggata
     1501 ttaaagaaag gagatatgct tatgaagatt tacaaaaaac tatttgctta tgtccaagat
     1561 aagaaatatc ttggggtttt ggccataatt ttttctgcta tatctactct acttacagta
     1621 tatggatatt atttaatcta caaatttcta gataagttaa taattaattc aaatttatcc
     1681 ggtgcagaga gcatagcatt aaaatctgtt attacactaa caagtggagc gatattttat
     1741 tttgtctcag gaatgttttc acatatcttg ggattcaggc ttgaaacaaa tttaagaaaa
     1801 aggggaatcg atggtctgga aaaagcaagt tttaggttct ttgacttaaa tccatctggt
     1861 caaataagaa agatcataga tgataatgca gcacaaactc atcaggtggt agctcacatg
     1921 attcccgata gctctcaggc aatagtcaca cctatacttg tccttgcact tggctttata
     1981 gtaagtataa gagttggcat aattttgctt gctcttacta taattggtgg cttaatttta
     2041 ggggcaatga tgggcgagca agaatttatg aagatatacc aagaatccct atctaaacta
     2101 agtgctgaaa ctgttgagta cgtgagagga atgcaagttg taaaaatatt taaagcaaat
     2161 gtagagtcat ttaaaagctt ttacaaggct ataaaagatt actcaaagta tgcttatgat
     2221 tattccctat cttgtaaaag gccttatgtt ttgtatcaat ggttattttt tggactgatt
     2281 gcaattttaa ttattcctat agtttatttt atgactagct tagctagcgc aaaggtgatt
     2341 ttacttgagc ttatcatgat tttattttta tcaggagttc tctttgtttc attcatgaga
     2401 atgatgtggt actccatgta tatttctcaa ggaaattatg cagtagatac tttagaggcg
     2461 ctttacgaag atatgcaaaa agacaaatta gtgcatggta atgtcaataa ttttaaaaac
     2521 tataatatag aatttgagaa tgttagcttt gcttataatg ataaagctgt cattgaaaat
     2581 ttatccttta atttagaaga aggaaagtcc tacgcacttg tcggttcatc tggatcaggc
     2641 aaatcaacag tagcaaaact tatatcaggt ttttacaatg ttaatgaagg aagcataaag
     2701 ataggcggga tagcaataag tgaatattct gacgaagcct taattaaagc catttccttt
     2761 gtttttcaag attcaaaatt attcaagaag agcatttatg ataatgtagc tttagctaat
     2821 aaagatgcga cgaaagatga cgttatgaga gccttaaaat tagcaggatg cgatttaata
     2881 ttagacaaat tcccagaaag agaaaataca atcataggct caaaaggtgt ttatttatcc
     2941 ggtggagaaa aacaaagaat tgcaattgct agagcaattt taaaggattc caaaattatt
     3001 attatggatg aagcatcagc atctattgac ccagataatg agtttgaatt gcaaaaagct
     3061 tttaaaaatc ttatgaagga taaaacagtt atcatgattg cacacaggct atctacaatt
     3121 aaagaccttg atgaaattat tgtcatggat agtggaaaaa ttatagaaag agggtctgac
     3181 aaagaattaa tgtcaaaaga tacaaggtat aagagcctgc aagagatgtt taacagtgcg
     3241 aatgaatgga gggtttcaaa tgaaagagtt ttataaaaaa agatttgctc ttacagatgg
     3301 aggagcaaga aatttaagta aagcaacact ggcttcattt ttcgtttatt gtataaacat
     3361 gcttcctgcc atattactta tgatttttgc tcaggaagtt ttggaaaata tgggcaaaag
     3421 caatggcttt tatatagtat tctcagtttt gactttgata gcaatgtata ttttgctttc
     3481 tatcgaatac gataaattat ataacacaac ctatcaagaa agtgcagatt taagaataag
     3541 gacagcggag aatttatcaa aattacctct atcttacttt tctaaacatg acatttccga
     3601 catttcacaa acaatcatgg ctgatattga aggcatagag catgcaatga gccactcaat
     3661 accaaaggtg ggcggcatgg tactgttttt cccattaata tctgtaatga tgctagcggg
     3721 caatgtcaag atgggtttag ctgtaattat tccatctatt ttaagcttta tatttatacc
     3781 tttatctaaa aaatatcagg ttaagggaca gaatagatat tatgatgtct taagaaaaaa
     3841 ctcagaaagc tttcaagaaa atatcgaaat gcaaatggag attaaagcat ataatttatc
     3901 gaaggatatt aaagatgact tatataaaaa aatggaagat agtgagagag tacacttaaa
     3961 ggcggaagta actacaattt taactttgtc tatatcttca atatttagct ttatatctct
     4021 tgctgttgtg atatttgtcg gcgtaaatct aattattaat aaagagataa attctctcta
     4081 ccttatagga tatttactag ctgctatgaa gataaaagac tctttagatg catctaaaga
     4141 gggcttgatg gaaatatttt atttatcgcc caaaatagaa agattaaaag aaattcaaaa
     4201 tcaagattta caagaaggcg atgactatag tttaaaaaaa tttgatattg atctaaaaga
     4261 tgttgagttt gcctacaata aagacacaaa agttttaaat ggtgtaagtt ttaaagctaa
     4321 gcagggagag gtcactgctt tggtaggtgc aagtggctgc ggtaaaacaa ctatcttgaa
     4381 acttatatca agactttatg attatgacaa gggacaaatc ttaatcgatg gcaaagatat
     4441 aaaagaaata tcaacagaat ctctttttga taaggtctct atagttttcc aagatgtggt
     4501 tctctttaat caaagcatta tggaaaatat tagaatcgga aagcaagatg caagtgacga
     4561 agaggttaaa agagcagcaa aacttgcaaa ttgcacagat tttatagaaa aaatggataa
     4621 aggtttcgat acagttattg gtgagaacgg agctgagcta tcaggaggag aaagacaaag
     4681 attatcaata gccagagcct tcttaaaaga tgcgccgata ttgatcttag atgagataac
     4741 agcaagcctt gatgttaaca acgagaaaaa gattcaagag tctttaaata atttagttaa
     4801 agataaaact gttgtaatca tttcacatag aatgaaatcc atagaaaatg cagacaagat
     4861 agtagttctt caaaacggaa gagtagaaag cgaaggtaag catgaagagc ttttacaaaa
     4921 atcaaaaatt tacaaaaatt taatagaaaa gacaaaaatg gcagaagaat ttatttatta
     4981 ggaggactac aatggataat aaaaaattaa aagtaaaaga tttagtaagc atcggtgttt
     5041 ttggcgtaat ttattttgcc ttcatgtttg gagttggtat gatgggcttg attccaatat
     5101 tgttcttaat atacccgaca gtattagcca tagttgcagg aactgttgtt atgttattta
     5161 tggctaaggt tcaaaagcca tgggcactat ttatatttgg tatgatatca ccacttgtga
     5221 tgtttgcagc tggtcatacc tacgtagttg tggttttatc acttatagta atgataatag
     5281 cagaattaat tagaaagatt ggtaattata attcatttaa atacaatatg ctttcttatg
     5341 caatcttcag cacatggata tgtagctctt taatgcaaat gcttttagca aaagaaaaat
     5401 atatggagtg gtctttgatg acgatgggaa aagattatgt tgatgtatta gaaaagttaa
     5461 taacttatcc tcatatggct ttagtagcct taggtgcttt cttaggagga attcttggag
     5521 catatatagg caaggctcta ttgaaaaaac acttttcaaa tggattatat tgtgtgggat
     5581 actttactcc ttgcctaatt ttatggtgtt atctgaatta aaccctatag ttaagatgtt
     5641 tttgagtata cctattgtta ttagaatgtt tattttacca tttatggcag caagctttat
     5701 gataaagacc tcggatgtag gcgcaataat ttcatcgatg gataagctta agatttcaaa
     5761 gaatgtatcc atacctattg ctgttatgtt tagattcttc ccatctttta aggaggagaa
     5821 gaaaaacatc aaaatggcta tgagagtaag agggataaat tttaaaaacc cagtcaaata
     5881 tcttgaatat gtttctgtgc cactactcat tatatcatct aatatagtca gatgacattg
     5941 caaaagcggc agaaacaaag gcaatagaaa atccaattgc caagaccaga tacattcgcg
     6001 taaagataca gctaattgat tttgtttatg ttttagcggt tgctggactt attgtgggag
     6061 gcttaatatg gttgaaataa aaaatttaag tcttgattat ggtgaagagc atatattaga
     6121 tgatatatca ctatccatag ccgagggaga gtgcgtgcta tttacaggaa aaagtggaaa
     6181 tggtaagtca tctttaataa attcaatcaa tggactagct gtaaggtatg ataacgcaaa
     6241 gacaaagggc aaaataatta ttgatggtaa gaatataaaa aatttggaac tttatcaaat
     6301 ctcaatgctt gtttcaactg tttttcaaaa tcctaagaca tattttttta atgtcaatac
     6361 gacattagaa ttattatttt atttggaaaa tatcggtctt gcaagagaag agatggacag
     6421 gcgtttgaag gatatgcttg agatattccc gataaaaaat cttttgaaca gaaatatatt
     6481 taatctatcc ggcggtgaaa aacaaattct ttgcattgca gcttcttata tagcaggtac
     6541 aaa
//
LOCUS       DAVDFK010000067         6324 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.67, whole genome shotgun sequence.
ACCESSION   DAVDFK010000067 DAVDFK010000000
VERSION     DAVDFK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.67"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..306
                     /locus_tag="VUR04_001932"
                     /pseudo
     CDS             1..306
                     /locus_tag="VUR04_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            473..679
                     /locus_tag="VUR04_001933"
     CDS             473..679
                     /locus_tag="VUR04_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341769.1"
                     /translation="MVASASASSTSTQAPAQEQVDKSELRALSQELDQRLKALATVSD
                     PKIDATKAVLLDAQKALEDSALTE"
     gene            704..1120
                     /locus_tag="VUR04_001934"
     CDS             704..1120
                     /locus_tag="VUR04_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341770.1"
                     /translation="MKTALDSLKDVIANARDSKPAQGKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQEPLDLVKEENGSAETEAKLVEELKAILDKLK"
     gene            1351..2058
                     /gene="ccdA2"
                     /locus_tag="VUR04_001935"
     CDS             1351..2058
                     /gene="ccdA2"
                     /locus_tag="VUR04_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET5341771.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWLGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMLYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2069..2626
                     /gene="sdbB"
                     /locus_tag="VUR04_001936"
     CDS             2069..2626
                     /gene="sdbB"
                     /locus_tag="VUR04_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET5341772.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNTDAEAAFKEMN"
     gene            3000..4391
                     /locus_tag="VUR04_001937"
     CDS             3000..4391
                     /locus_tag="VUR04_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET5341773.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPSLVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYRHSTIGE"
     gene            4534..5451
                     /gene="adcAII"
                     /locus_tag="VUR04_001938"
     CDS             4534..5451
                     /gene="adcAII"
                     /locus_tag="VUR04_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET5341774.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5459..>6324
                     /gene="phtD"
                     /locus_tag="VUR04_001939"
     CDS             5459..>6324
                     /gene="phtD"
                     /locus_tag="VUR04_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET5341775.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSER"
BASE COUNT         1934 a         1139 c         1335 g         1916 t
ORIGIN      
        1 ccagaaaaag tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt
       61 tagattgatg aaacaggatt caatacttat ttttatcgag aatatggtcg ctcattaaaa
      121 ggtcagttaa gaagaggtaa agtatctgga agaagatatc agaggatttc tttggttgca
      181 ggtctaacaa atggtgagtt aatcgctcca atgacttacg aagagacgat gacgagcgac
      241 ttttttgaag cttggtttca gaaatttctc ttaccaacat taaccacacc atcggttatt
      301 atagtgaaat ggaataagaa caggacaaat cgatcaagac agtaaaatcg aattctaaca
      361 atgttttaga agtccatatg tactattcta gtttcaatat accataactg ctcctagtca
      421 acctgcaagt cctgtcccag ctccaagctc agctccgact caagatccta gagtggtagc
      481 aagcgcttcg gctagctcaa cgagcacaca agctccagct caagagcaag ttgacaagtc
      541 tgaacttcgt gccttgagtc aagagttaga ccaacgcttg aaagctttgg caacagtatc
      601 tgatccgaaa atcgatgcaa ccaaggctgt cctcctagat gctcaaaaag ctctggaaga
      661 tagtgccttg acagagtaag gtctgcatac tgcagtagag tctgtgaaga ctgccttgga
      721 ctctctcaaa gatgtgatag caaatgctag agacagtaag cctgcacagg gcaagaagga
      781 tgcaaaacaa ggaacggaag atagtaagga ttcagataag atgactgaaa caaactcagt
      841 tccggcagga gtgattgtgg tcagtctact tgccctccta ggcgtgattg ccttctggct
      901 gattcgccgt aagaaagagt cagaaatcca gcaattaagc acggaattga tcaaggttct
      961 aggacagcta gatgcagaaa aagcggataa aaaagtcctt gccaaagccc aaaaccttct
     1021 ccaagaaccc cttgatctcg tgaaagaaga aaatggctca gcagagacag aagctaaact
     1081 agtagaggag cttaaagcaa tccttgacaa actcaagtaa aacatgattt atgaaatgtc
     1141 agacctaaaa gacattttcg ttcacaaaat cagcgacgag caatccttgt cgttgctttt
     1201 tggctatttt gggggataag atccgccttg actcgcaaaa gaaaagattg gtccaatagt
     1261 gcccgatacg attttgtgta gcagaaagct tacaaataaa attgaatata gtaaaatagg
     1321 attagaatta ttaagaaagt tggttcttta ttggaaacga tagtattttt aatctctgtt
     1381 tttctagcag gtgttttatc ctttttttct ccctgtattt ttcctcttct gccagtctat
     1441 gctgggattt tattggatga tcaagaaagt gcaaaaagct tttctttgtt tgggagaaag
     1501 gttctctggt taggcttgat tcgaacactt tgctttatcg ctggtatctc tctcattttc
     1561 tttattctag gctttggtgc tggttacttt ggtcatattc tctatgcaaa ttggtttcga
     1621 tatggcatgg gagctattat tatcattttg ggtcttcacc agatggaaat ttttcatttg
     1681 aagaaattag aagttcaaaa aagttttacc tttaaaaaat cagattctaa tcgttattgg
     1741 tcagcttttt tacttggtat tacctttagc tttggttgga caccttgtat tggtccagtt
     1801 ttaagttctg ttttagcact tgcggcttct ggaggcaatg gtgcttggca aggagcaatt
     1861 tatactctca tttacactct gggtatggcc cttcctttct tggtcttggc actagcttca
     1921 ggtctagtca tgctatattt tagtaaaatc aagcgtcata tgatgctact aaagaaaatt
     1981 ggtggtttcc tcattgtttt aatgggaatt ttgttactat taggacaagt aaatgttcta
     2041 gctggaattt ttgaataaag gaggacaaat gaaaaaagta atgtttgctg gcttaagtct
     2101 cttgtcatta gttgtattga tggcctgtgg tgaggaagaa actaaaaaga ctcaagcagc
     2161 acaacagcca aaacaacaaa cgactgtaca acaaattgct gttggaaaag atgctccaga
     2221 cttcacattg caatccatgg atggcaaaga agttaagtta tctgatttta agggtaaaaa
     2281 ggtttacttg aagttttggg cttcatggtg tggtccatgc aagaaaagta tgccagagtt
     2341 gatggaacta gcggcgaaac cagatcgtga tttcgaaatt cttactgtca ttgcaccagg
     2401 aattcaaggt gaaaaaactg ttgagcaatt cccacaatgg ttccaggaac aaggatataa
     2461 ggatatccca gttctttatg ataccaaagc aaccaccttc caagcttatc aaattcgaag
     2521 cattcctaca gaatatttaa ttgatagcca aggaaagatt ggaaagattc aatttggtgc
     2581 tatcagtaat acggatgcag aagcagcatt taaagaaatg aactagaatc gataaaatct
     2641 gattacaaga tgtagtcaga ttttggtaac ttctaaaact aacttccagt ttcccacaac
     2701 ctagctttta gtatgagaaa aacgcgtgac atcagtggaa atccgtctta gactaacttc
     2761 cactggtttt ctttttcttg atatataagg gttcaaaagc gaaaagactc agaaaaagtg
     2821 cacgacaaat agccctaaaa cagagtcgtc ttagagtaat ttccagtttt gggagagaga
     2881 tggaagttac tttgagaagt tacggtagtc agattttttt agaaaaacat tttataaata
     2941 ttcacatatc tcctatattt atggtaaaat agaattatca gtttattttg gagtcaaaga
     3001 tgaatatatt tagaacaaag aatgttagtt tagataaaac agagatgcat aggcatttga
     3061 agttatggga tttgattttg ctgggtatcg gagccatggt agggacaggc gtctttacaa
     3121 tcacaggtac tgcagctgca acacttgctg gcccatccct agtgatttca atcgttattt
     3181 ctgccttgtg tgtgggatta tcagccctct tttttgcaga atttgcctcg cgagtacccg
     3241 ctacaggagg tgcctatagt tacctctatg ctatcttagg agaattccct gcctggttgg
     3301 ctggttggtt aaccatgatg gagttcatga cagccatatc aggcgtagct tcgggttggg
     3361 cagcttattt taaaggcttg ctctctcaat acgggatagc ccttcctcag gctttaaatg
     3421 gtacctttaa tcctcaagca gggacatttg ttgatttatt gcctattctt gtcttggtct
     3481 tggtgacttc gcttgtttta ctaaatgcca aggcagcctt acgctttaat tcgattctag
     3541 ttattttgaa attttccgct ttagctctct ttgttttagt aggaatttgg aatattaagt
     3601 ttgataattg gagcaatttt gctccttacg gttttggaca aatctatgga gctagcactg
     3661 gtattatggc tggtgcgtcc ttgatgttct tcggtttttt gggatttgaa tccatctcta
     3721 tggctgtaga tgaagtcaag actcctcaaa aaaatattcc tagagggatt gtcttatcgc
     3781 tttctatcgt aaccattctc tatgccttgg tgacccttgt tttgactggt gtggttcact
     3841 atagtcattt aaatgtcgat gatgccgttg cctttgccct tcgtagtgtt gggattagtt
     3901 gggcagccaa ctatgtgtca ttagtggcta tcttgacctt gattacagtt tgtatttcga
     3961 tgacctatgc cctatcgcgt atgatttaca gtttagcacg tgacggctta gtgcctgctg
     4021 cctttaagga actgacgaag actagcaaga taccaaagaa tgctactatc ttgacaggtc
     4081 tagcttcagc agtagcagca ggaatgttcc cactagccag tattgcagcc tttttaaata
     4141 tttgtacctt agcctacttg atcatgttgg cttatggtct gattcgctta cggaaagaaa
     4201 aaggaatgcc caaagctggg gaatttaaaa caccattggt acctctgtta ccaattttat
     4261 cgatcatcat ttgtttatcc ttcatgttac agtataatat gaatacctgg attgctttcc
     4321 tagttgcgtt gttagtagga agtattattt acttcactta tggctatagg cattctacca
     4381 taggagaata aagtgaaagt ctattgagtt gttgacactc agcagatttt tatatgtgaa
     4441 agaaatttca aattttttct aaaaatatct tgacagatta aattttcagg agtagaatat
     4501 ttactagtta attaaatggt taaggagttg ttcatgaaga aacaaaattt atttttagtc
     4561 ctgttaagtg tctttctttt gtgcttgggg gcttgtggtc aaaaggaaag tcagacagga
     4621 aaggggatga aaattgtgac cagtttttat cctatctacg ctatggttaa ggaagtatct
     4681 ggtgacttga atgatgttcg gatgattcag tcaagtagtg gtattcactc ctttgaacct
     4741 tcggcaaatg atatcgcagc catctatgat tcagatgtct ttgtttacca ttctcataca
     4801 ctcgaatctt gggcaggaag tctggatcca aatctaaaaa aatctaaagt gaaggtttta
     4861 gaggcttcag agggaatgac tttagaccgc gtccctggac tagaggatgt ggaagcaggg
     4921 gatggagttg atgaaaaaac gctctatgac cctcacacat ggctagatcc tgaaaaagct
     4981 ggagaagaag cccaaattat cgctgataaa ctttcagagg tggatagtga gcataaagag
     5041 acttatcaaa aaaatgcgca agcctttatc aaaaaagctc aggaattgac taagaaattc
     5101 caaccaaaat ttgaaaaagc gactcagaaa acatttgtaa cacaacatac agccttttct
     5161 tatctagcga agagatttgg gcttaatcaa cttggtattg caggtatctc tcctgaacaa
     5221 gaaccaagtc cacgacaact aacagaaatt caggaatttg ttaagaccta taaggttaaa
     5281 acgattttta cagaaagtaa cgcttcttca aaagtagctg aaactcttgt caaatcaaca
     5341 ggtgtgggtc ttaaaactct gaatccttta gagtcagacc cacaaaatga caagacctat
     5401 ttagaaaatc ttgaagaaaa tatgagtatt ctagcagaag aattaaagtg aggaaagaat
     5461 gaaaatcaat aaaaaatatc tagcaggttc agtggcagtc cttgccctaa gtgtttgttc
     5521 ctatgaactt ggtcgtcacc aagctggtca ggttaagaaa gagtctaatc gagtttctta
     5581 tatagatggt gatcaggctg gtcaaaaggc agaaaatttg acaccagatg aagtcagtaa
     5641 gagagagggg atcaacgccg aacaaatcgt catcaagatt acggatcaag gttatgtgac
     5701 ctctcatgga gaccattatc attactataa tggcaaggtc ccttatgatg ccatcatcag
     5761 tgaagagctc ctcatgaaag atccgaatta tcagttgaag gattcagaca ttgtcaatga
     5821 aatcaagggt ggttatgtca ttaaggtaaa cggtaaatac tatgtttacc ttaaggatgc
     5881 agctcatgcg gataatattc ggacaaaaga agagattaaa cgtcagaagc aggaacacag
     5941 tcataatcac gggggtggtt ctaacgatca agcagtagtt gcagccagag cccaaggacg
     6001 ctatacaacg gatgatggtt atatcttcaa tgcatctgat atcatcgaag atacgggcga
     6061 tgcctatatc gttcctcatg gcaatcactt ccactatatt cctaagagtg atttatctgc
     6121 cagtgaatta gctgctgccc aagcctattg gaatgggaag cagggatctc gtccttcttc
     6181 aagttctagt cataatgcaa atccagctca accaagattg tcagagaacc acaatctgac
     6241 tgtcactcca acttatcatc aaaatcaagg ggaaaacatt tcaagccttt tacgtgaatt
     6301 gtatgctaaa cccttatcag aacg
//
LOCUS       DAVDFK010000068         5838 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.68, whole genome shotgun sequence.
ACCESSION   DAVDFK010000068 DAVDFK010000000
VERSION     DAVDFK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.68"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(116..1126)
                     /gene="ccpA"
                     /locus_tag="VUR04_001940"
     CDS             complement(116..1126)
                     /gene="ccpA"
                     /locus_tag="VUR04_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET5341776.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1551..2150)
                     /locus_tag="VUR04_001941"
     CDS             complement(1551..2150)
                     /locus_tag="VUR04_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5341777.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2152..3249)
                     /locus_tag="VUR04_001942"
     CDS             complement(2152..3249)
                     /locus_tag="VUR04_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5341778.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRAIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(3249..3986)
                     /locus_tag="VUR04_001943"
     CDS             complement(3249..3986)
                     /locus_tag="VUR04_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5341779.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(3988..4872)
                     /locus_tag="VUR04_001944"
     CDS             complement(3988..4872)
                     /locus_tag="VUR04_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5341780.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(4859..5053)
                     /locus_tag="VUR04_001945"
     CDS             complement(4859..5053)
                     /locus_tag="VUR04_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341781.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGLGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(5050..5256)
                     /locus_tag="VUR04_001946"
     CDS             complement(5050..5256)
                     /locus_tag="VUR04_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5341782.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1859 a         1291 c          958 g         1730 t
ORIGIN      
        1 agtgtgttgc acagccttta accagccgcc tagtccgctc tatggtattc attaagtcaa
       61 catctcttgt ttaagagcac aaaatcagga aatcttctcg attccctgat tttttctatt
      121 tacgttttcg tgttgagcta cgttctgtca aaccatgagg taagagaact tcacgttctt
      181 ccaactcttc cttatgcata atcttggtca acatacgcat actaatggca ccaaggtcat
      241 aaagaggttg ggcaatcgtt gtcaagtttg gacgggtaaa gcgtgagatt tgtgaatcat
      301 cactagtaat aatttcaaaa tcttctggca cagaaacacc cttatcagcc aaaccgttca
      361 agactcctgc tgccaactca tcacctgtca caactgctgc agttgcattt gatgaaatca
      421 aacgctctgc taaggcgtaa ccatcatcat agctatattt agattcaaat accaaaccct
      481 cactataagc gattcctgct tttttcaagg tttccttgta gccaactaaa cgaaccttac
      541 cattgatgtc atccactagc ggaccgctaa cgaaagcaat acgctcattt tctttagcaa
      601 ggtaactcac tgcatcaatt gttgcttgct tatagtcaat attgacactt ggcaactggt
      661 gctcaacatc gacagttcct gcgagaacaa tcggagtacg tgaacgcgaa aattctgagc
      721 gaattttatc tgtcaagtga taacccatat agataatgcc atctacctgc tttgaaaaga
      781 gggtattgac aacagaaact tctttctcgt tatcttcatc gctattagct aggacaatat
      841 tgtacttgta catttctgca atatcatcaa tccccttagc caaactcgaa aaataaccat
      901 tggtaatatt tggaatcacg acaccgacag tggttgtctt tttacttgca agaccacgcg
      961 caactgcatt tggacgataa tccaaacgat caattacctc tagcactttt ttacgggtat
     1021 tctcttttac atttttattg ccattgacca cacggctgac cgtcgccatg gaaacacctg
     1081 cttcacgagc gacatcataa atggttactg tatcatctgc attcattcct tttcctgtcc
     1141 tttctatctc acacattctt ttacaagtag aggtactgat tgaagctcta tatctactta
     1201 caaaagtgaa gatgtgaaaa tttcgttttc atatttctac ttattccatt ctatcactaa
     1261 ttgtaaacac tttcaagtgt tttttgaaga ttgattgaaa aaatttcata gaaaacctag
     1321 gtttagctcc ttgctaccac cttagactaa acaaaaagga ggaaactaag ccctcctaaa
     1381 gttatagtaa aatgaaataa gaacaggata aatcgatcag gacagtcaaa tcgatttcta
     1441 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tctactatag gtattgttcc
     1501 attcactacc gtcaatttta gcacatagtc ttcatgaaaa tattatatca tcataaccaa
     1561 ccagattctt ttgcgatatt agctgcctct gttcgattac cagcatccaa ttttgaaaga
     1621 atattggtga catagtttcg aatagttccg tttgagaggt aaagctgatc tgcgatttct
     1681 tggttggata agccccgggc gatccccttt aagacagcaa tctcttgttc tgtcaacgga
     1741 ttgggacggg tcatcaccac ttccatcaat tcaggcgaat actccttgcg tccttcgagg
     1801 acggtgtgca aggtttgcat gaggtctgca acgcttcgtt cctttaatac ataagcatcc
     1861 actccagcct tgaccgcacg ttcaaaatac ccagcacgct tgaaggtcgt caccacaacc
     1921 acctttgttt caagcctttc tgatcgtatc cactccaaga cttcaagacc tgtcttaaca
     1981 ggcatttcta cgtcaaggat ggcgatatct acagactcct tttctaatag ttggattgct
     2041 tcttgcccat tcttggcttg aaggacagac tccacatctg gttgaagcgt gagcaattga
     2101 cacatggcat ctcgcaacat actttgatct tctgcgacta atactttcat cttagtttct
     2161 ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga ttacacttac
     2221 ttctcctgaa aatggaaaaa cacgatctcg gattgtatgg agctcatctc cttttagaaa
     2281 agcaaagccg cagccatcat cacttactgt taaaatgagt tccttctctg tccgttctaa
     2341 ttttaagtaa gctttagacg ctttggcatg tttgatgata ttggtcacca actcaagcaa
     2401 aatcatagaa gccattgact ccaattcttg agtaaggcta gcagtatcta gttggttatc
     2461 tgtttccacc tcaattccag caatttctaa catctttttc acagtctcta gttcggatgt
     2521 caaagttcta gacttaagat tttccacaat ggctcgaact tcacgcattg attctttgct
     2581 aatttgctgt atttctctta attccttttc cacttgtgga taagcctgca tttgaaatag
     2641 ctgcaaggct agatctgtct tgacactaag catagcaaag gtatgtccca gactatcatg
     2701 caaatcctga ccgatacgat tgcgctcatt ttctgctagc aatagattta tctgggtatt
     2761 ttgcttgacc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg agcccaaagt
     2821 catcaaatcg acaaaagtaa gaattacaag catatagact agaaactcaa cttcgattct
     2881 ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca aggagaaatg tccatacatg
     2941 taaagacttt aaactacgta cgccaaaatg ataaattaag agattggaaa ggaaaaagaa
     3001 aaaccagata taattcccag caacaaaggc ggtattccca gctacataga ccagcatgat
     3061 cccccagaaa agccaagata ggcgctggtt cttagttatt aaaacaccca aatacgtcac
     3121 tacaaataga atatcaacca ataaatgcca agcaggaagc tccccaatca ctacaggtag
     3181 gatgggaaaa agcataaaaa tcaaactggc ccaaaacata tagtgtatgc ttttcagtct
     3241 ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tagtcaaacc aaataaaact
     3301 gctgaaaaaa caagtaaata aactgtggct gatagattga tgccaccctc gtttaagaag
     3361 gtcttgagca actccatcaa ttgataggtc gggagacatt taccaactgc ttgcatccag
     3421 tctggaaata aagaaatggg catccagagt ccgcctaaaa cagccaatcc tagataaaga
     3481 agattgccca caacagacat cagctgacta gttggtaaga gagtcaaggt caagccaagt
     3541 gctacaaaag caatactccc cacaatcagc aaaatcgcag ctccaaccca ttttactaga
     3601 ggcatgtcta cacctcttac aaaatgtcca actgtaaaaa caaccagaat tgagaccaaa
     3661 taatcaacca gcatacttgt tatctttgat agataatatt ctaccatatt tacagggcta
     3721 tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaaaacagc tggaaatgag
     3781 aggatagttg tcgacatcat ggaaaaggca gtcatggaga tgaggtaatc acgcataaaa
     3841 ttcgcgggtt cacctggtgt gtcctgatag ataccagaaa aaaataaata gaaagccgtc
     3901 ggcatcccta ccgacaatag ataatagatt aattgtcgtt tggtcaataa aaattctatc
     3961 ttactaagtg ctatccatcg tttcatctta gttatctccc ttctgcgtct cttcaaagat
     4021 tgtattcaac aaactacgat tattaacttc gatttcttgc atcctacatc ctgcttgggc
     4081 taatagttcc cagaaagcat ctgcttctcg agtgactact tgtaaagaat cttgctttag
     4141 ggtccagttt tcaaccaaat ttgactgctc tacgacttcc ttgtaagcta taggaaggat
     4201 aaagtgcttt tctatttcct cgctacgcat agctagaggc gtcgtatctc gaatcaactc
     4261 tcccttattt aagagcaaaa tgcggtctgc agtgtgttcc acttcctcaa tataatggga
     4321 cgaatagaga atggtgactc cttgcgcttt taactcctgg acaatttccc aaaaacgttg
     4381 acgagttgag gtatccatgg acgcagtagg ctcatctaaa aaaacaatct ttggtcgccc
     4441 aattaaggtc aagacgaaag aaaagagacg cttttgaccg cctgataatt tttctgccaa
     4501 ctgttctttt tgttgcttga caaactgcaa cagttgatca atttcctgat tgctcaaagg
     4561 atttggatag atacgttgaa agaaagcaat caactcttta acttttaatt tctgaacgat
     4621 tacattttct tgagggaggt aagccctagt atagtctaac ttagaactcg tcactggtaa
     4681 accttgaata gatacttgac cgcttgtgac cagtttatct ccaagcaaac aatctaagag
     4741 tgttgtcttt ccggcaccat ttggaccaat taaggcaaca cattcaccat cgttgatttc
     4801 aaaggagatg ttccgcaaaa tttccttgtc ttttattttc ttactcaatt tttcaacttt
     4861 aaccacagtc atgagactct cctttcaacc actccattcc catagggaaa acgacgaaaa
     4921 tcataaatcc aagccccaaa gcaccatgaa tgaattggcg aagcaaggct tgatcaaacc
     4981 aatcagtaaa catttccact aaccatacca agagtgacag gccgataaag aaatagatga
     5041 tccctctctt cattcctcaa actccttttt cacatctctg actaatttca aaccttctct
     5101 aacaagccaa gacatgattc caaagccagc aaagaccttc caaggaaaat ggtagaaatc
     5161 ctcatccaat cccgaaaaca tgagataggt cataactcct gctactacta aactcattgc
     5221 aataatcatt ttatttctca tctcttcttc ccccatttca tactacaatt atagtctttt
     5281 aaaatcagag gaggcagaag cttctgtcac tagaaaatat gacaaatgtc ataaaaaatt
     5341 ctgttcaaaa caagcaagat acactataca ataaaacaca atcagaaaaa tctaaggcaa
     5401 cttcctcaaa agagatatca aacccaattc acaccataat gtaaactaat acttatttaa
     5461 aatcaaaaag agtagaaatt tttatcagac aaacacatat atagtgtatt gaatctataa
     5521 cagtaggcct taaatactaa aatatttcta taaattaatt taactttcct gatagaactg
     5581 ttcatatctt atttcaattc tctatattat acgttgaaca aaacccttct attgctttct
     5641 taaaaattta taagagttat aaaatctgtt aaatttcaat gtgtatatct aaactacggt
     5701 atttattgaa aagactggag acaaaaagta tacgctgcca aaatgaatta ctgaaaatca
     5761 aaaaagagag aaccaaactg attccctctt aatgtatata atatctagtt ttaaaaatac
     5821 acactcacat atctctgt
//
LOCUS       DAVDFK010000069         4072 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.69, whole genome shotgun sequence.
ACCESSION   DAVDFK010000069 DAVDFK010000000
VERSION     DAVDFK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4072
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.69"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(478..1011)
                     /locus_tag="VUR04_001947"
     CDS             complement(478..1011)
                     /locus_tag="VUR04_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET5341783.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTRELAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1100..1876)
                     /gene="recX"
                     /locus_tag="VUR04_001948"
     CDS             complement(1100..1876)
                     /gene="recX"
                     /locus_tag="VUR04_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET5341784.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1886..2662)
                     /locus_tag="VUR04_001949"
     CDS             complement(1886..2662)
                     /locus_tag="VUR04_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HET5341785.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     KLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKWTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2719..>4072
                     /gene="rlmD"
                     /locus_tag="VUR04_001950"
     CDS             2719..>4072
                     /gene="rlmD"
                     /locus_tag="VUR04_001950"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET5341786.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1297 a          702 c          733 g         1340 t
ORIGIN      
        1 acagaatcta aagaatctgg aattaaacaa atggacaatg tcataaaata ttttgagttt
       61 attgaatcta aaagtattgc tttatatttt caaaaacgat taaatgagct gatagattaa
      121 atatcatttt ctctgttaag atattgtttt taaaatattg tactaaatga ttgatgctat
      181 gtggaaatac aaaaaaatgt ttttgatacg aagttgacct gtatttttta tactaatcat
      241 tttcgtattt tttgtattaa acgatataag tttgttgtaa acttactagg aataaagaca
      301 ttaaaaaata atagtatatc tatttgtttt atatatttta cgaattctgc ataaatctct
      361 ttctagtaat gtgttgtaac tctgctataa tggatttatt cctttttgtg tttacacaat
      421 ttattttata ctaccaaaaa aacaaggtca ggattttgtt cctgaccttt gacaacttta
      481 ccgattcttt agttctacat agcgcttgta ccaaatgttt acataggctt ctgagaaagg
      541 accacgtcca ttgttaatcc aatcaacaag aattttgaca tgttctttta aaatatagtc
      601 caagtcatca gaataattca ttttgcgttt gtgacgctcg tattcttcaa cgtccaagag
      661 acgtttttcc ccatctgtaa aaattttaac atccaaatcg taatcaatat acttcagtgc
      721 ttcttcatcc agatagtagg ggctagccat attgcaatag taagaagttc cattatcacg
      781 aatcatggca atgatattaa accaatattt cttgtgaaag taaacaatag ccagttctcg
      841 agtgacccaa cgacgaccat cactttcggt aacaagtgta tgatcgttga caccaataat
      901 ggcgttttct gttgttttta gtaccatggt gtcccgccaa gttcggtgga gactcccatc
      961 atgcttataa ctttgaattg taataaagtc gccttctttt ggaagcttca taactaacca
     1021 actttctaca atttataagt ttatcattta ctattgtacc ataaaattac ctaaaatctg
     1081 tgaatttcac ttggaaatat taaagatatt ctctaagagc gcttgctata tccgaaaaat
     1141 cgtagccctt tcgtgctaaa acttgagtta aacgctgctt cagttcgtat ccttcatact
     1201 ttcgggcata cttagtatat tgcttatcaa gttccttgaa gatgagttcc tgagtcgttt
     1261 cttggtcaac ttgactatcc aattcgtcaa aggcaatttt agcatcaaaa taagagaagc
     1321 ccttgttagt caagttctgg ataatcttat cttgcagggc acgagctgga agttttccct
     1381 catatttttt caatagttta ttggctacac gttgagcaac ttccgaaaaa tcaaaatcat
     1441 tcaagatttc ttctatagta gattttgaaa ttcctttttg tgctaatttc tgagtcagta
     1501 cataaggtcc cttgtctcct gaaacttgat tggcattgat gatagcataa gcgtactgac
     1561 catcattaat ccacttatct tctttaagat tagcaataac ttgagaaacg atgtttttat
     1621 caatatcgta ttttttcaga tattctctga cttctttttc agtgcgtgct ttaaaggata
     1681 agtggtagag ggccagattc ttaccataag aaaattgagc aaagtcttga atctctttca
     1741 attcctcttc gcttatcacc ttatctctcg ataacataaa acgaacaatt gtatcttcgg
     1801 tgatatagca tttgtcgcca ttatcaagct ccatcagata gagtcttttt ttcttttcaa
     1861 gttttgtgat tttcataatt tcctttcatc taaatgcttc gaaagctgca acaagtcgga
     1921 gtttatccat atttacatat tctctaccgt aatagtcgag aaataattca gcatacgtag
     1981 catcttgtag gttgtaatga agggaccaaa ttgcccaaaa gaggtcgata tgtcggtcac
     2041 taaaaccagc caatcccaag tcaataaagc aagaaaaatg agaggcatcc ttcaagatga
     2101 aatttggcag gcaggcatct ccatgaataa aagcatcagc tttgagaatg taacctttct
     2161 cttgtatcag ttggtaagct tcttcacgac tgtgaatgtg aaattgaggc agaagagtct
     2221 tgttataaaa agtccacttc tgatagtttt ttaaggcttt ttctttataa cgcttcagat
     2281 gattttccga cggaaaagat tgtggtttaa gactgtgaag tttgtttaat gcttgagcca
     2341 gggtttgaca gagtttttcg ggttgattta aaaaagcgag agcgttgctg ccaatggctt
     2401 ctttagtcag aaggaagtcc ttatttgctg ataaataggt aatcactgga gttcccaatc
     2461 cttcagtttc gaaccaactt gcaatcttag cttcttgagc taatctgcct ttttgatcta
     2521 tttttaaata gtaacctgaa tctatatata ggacagttgc acttgaatga gaagaactat
     2581 cagagagatt agctcccttg atatagcttc gtaattgttc agggaaatct agtatactaa
     2641 agcgaggtgt ttttgaattc atgcttttat tgtaacatat tcttaaatat cttagaaact
     2701 ccatggtata atagacatat gaatctgaaa gtgaaacaaa aaataccatt aaaaatcaag
     2761 cgcatgggaa ttaacggtga gggaatcggc ttttaccaaa aaacattagt ctttgtacca
     2821 ggagctctca aaggcgaaga tatctattgt cagattactt ctattagacg caactttgtt
     2881 gaagcaaaat tactgaaggt caacaagaag tctaaatttc gaattgtgcc atcttgtact
     2941 atttataatg aatgcggagg ctgccaaatc atgcacctgc attatgataa gcagctggag
     3001 ttcaagacgg acttacttca tcaagcgctg aaaaaatttg ctcctgcagg atatgaaaat
     3061 tatgaaattc gtccaaccat tggaatgcag gaaccaaaat attacagagc taagttacaa
     3121 tttcagactc gaaaatttaa aaatcaggtc aaggcgggct tatatgcaca aaactctcac
     3181 tatttagtag agttgaaaga ctgcctggta caagataagg aaacccaagt gattgctaat
     3241 cgcttagcag aattacttac ttatcaccag attccaatca cggatgagag aaaagttcta
     3301 ggtgtccgta ctattatggt ccgacgcgcg agaaagaccg gacaggttca gattattatt
     3361 gttacaaacc gccagcttaa tttaactcaa ttggtaaaag agttggttaa agatttccca
     3421 gaagttgtga cagtagctgt taatacaaat acagctaaaa ccagtgagat atatggtgaa
     3481 aagacagaga ttatctgggg gcaagagagt attcaagaag gtgtactcaa ttatgaattt
     3541 tcactatccc ctcgagcttt ttatcaacta aatcctgagc aaacagaagt cctctatagc
     3601 gaagcagtaa aagcgctgga tgttgataaa gaagaccatt tgattgacgc ttattgtgga
     3661 gttggaacga ttggatttgc ctttgcaaag aaagtaaaaa cactcagagg tatggatatt
     3721 attccagaag ctattgaaga tgccaagcga aatgctaaaa gaatgggatt tgacaatact
     3781 cattatgaag ctggaacggc agaagagatt attcctcgtt ggtacaagga aggctaccga
     3841 gcagatgctt tgattgttga cccaccacgt acaggtctgg atgataagtt attagatact
     3901 attcttactt atgtaccaga aaaaatggtt tatatttctt gtaatgtttc gaccttggct
     3961 cgtgatttgg tacgcttagt agaagtctat gatcttcatt atatccagtc ggtcgatatg
     4021 ttcccacata cagctcgaac tgaagctgtt gtaaaattaa taaaaaaagt tt
//
LOCUS       DAVDFK010000070         3272 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.70, whole genome shotgun sequence.
ACCESSION   DAVDFK010000070 DAVDFK010000000
VERSION     DAVDFK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.70"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            77..484
                     /locus_tag="VUR04_001951"
     CDS             77..484
                     /locus_tag="VUR04_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5341787.1"
                     /translation="MARYGIYAVIPNPEQKQIVLVQKPNGAWFLPCGEIEVGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLEDFN
                     HITWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            649..948
                     /locus_tag="VUR04_001952"
     CDS             649..948
                     /locus_tag="VUR04_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET5341788.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1089..2437
                     /locus_tag="VUR04_001953"
                     /pseudo
     CDS             1089..2437
                     /locus_tag="VUR04_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2652..2975
                     /gene="tnpB"
                     /locus_tag="VUR04_001954"
     CDS             2652..2975
                     /gene="tnpB"
                     /locus_tag="VUR04_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET5341789.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(3116..>3272)
                     /locus_tag="VUR04_001955"
     CDS             complement(3116..>3272)
                     /locus_tag="VUR04_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET5341790.1"
                     /translation="KEIRKRGFKNKAFQTLEDVMNQLQDVIQGLEKEVIKSIVNRRWN
                     RMLFENR"
BASE COUNT         1157 a          600 c          591 g          924 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactttc ggagaaaaaa
       61 agcaaataca gactatattg ctcgctatgg catatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aaaaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagtaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca agctgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaagacttta atcatattac ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcagc tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata ataaaacgca tagtatcagg
     1021 tgccgaaatg aactgccccc ccaaaaaaag ttagacagaa aaaatctaac ttttggggtg
     1081 tttttattat gaaattaact tatgatgata aagttcagat ctatgaactt agaaaacaag
     1141 gatatagctt agagaagctt tcaaataaat ttgggataaa taattctaat attaggtaca
     1201 tgattaaatt gattgatcgt tacggaatag agttcgtcaa aaaagggaaa aatcgttact
     1261 attctcctga tttaaaacaa gaaatgatta ataaagtctg acatgaaggc tagactaaag
     1321 atagagtttc tcttgaatac ggtctcccaa gtcgtacgat acttcttaac tggctagcac
     1381 aatacaggaa aaacgggtat actattgttg agaaaacaag agggagagta cctaaaatgg
     1441 gacgtaagcc aagaacgaga cctgaagaga ggacagaatt agaacgtctt caagcagaaa
     1501 atgagtacct gagagcggag aatgccatcc taaaaaagtt aagagaactc cgattgaagg
     1561 aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa ttaatgactg agttttcgtt
     1621 agatcttctt ctaaaatcca ttaaactagc tcgttcgacc tactactatc acttgaaaca
     1681 gctagacaaa acagataagg accaagagct taaagctgaa attcaatcca tctttatcga
     1741 acacaaggga aattatgctt atcgtcggat ttatttagaa ctaagaaatc gtggttatct
     1801 ggtaaatcat aaaagagttc aaggcttgat gaaagtactc aatttacaag ctaaaatgcg
     1861 acagaaacga aaatattctt ctcataaagg agacgttggc aagaaagcag agaatctcat
     1921 tcaaggccaa tttgaaggct ctaaaacaat ggaaaagtgc tacacagatg tgactgaatt
     1981 tgccattcca gcaagtactc aaaagcttta cttatcacca gttttagatg gctttaacag
     2041 cgaaattatt gcctataatc tttcaacttc acccaactta gaacaagtac aaacaatgtt
     2101 ggaacaggca ttcacagaga agcactacga gaatacgatt ctccatagtg accaaggctg
     2161 gcaatatcaa cacgattctt atcatcggtt cctagagagt aagggaattc aagcatctat
     2221 gtcacgtaag ggtaacagcc cagacaatgg tatgatggag tccttctttg ggattctgaa
     2281 atcggaaatg ttttacggtt atgagaagtc gtttcagtcg cttaagcaat tggaacaagc
     2341 tattgtagac tatattgatt actacaacaa taaacgaatt aaggtaaaac taaaaggact
     2401 tagccctgtg caatacagaa ctaaatcctt cagataaatt aattgtctaa cttttggggg
     2461 gcagtacact acacccacta ttatgcgttt ttatcatttt gaaatctact gctaatcaat
     2521 gaagaagcaa agatcaaact aggcagctag ttacaagtta cgtaagcgcg tcataacaag
     2581 gtatctatcc taattcccca acttccaata tactagataa aaaataatta tcggagaaaa
     2641 gatattgtac tatgataatt caactaagtg atttaggtca agttcacctt gtttgtggca
     2701 agacagatat gaggcaggga atagactcat tagcctatgt agttaaaacc cactttgaat
     2761 tggatccttt ctccgatcaa gtctttctct tttgtggtgg acgtaaagac cgctttaaag
     2821 tcctttactg ggatggtcaa ggattttgga tattatataa acgctttgag aacggaaaac
     2881 tgacttggtc cagtacagaa aaggatgtca aagctctcac atctgaacaa gtagactggc
     2941 ttatgaaggg cttttctatc actccccaaa tatagtggat ttaaactaga atagtacacc
     3001 tctgcttcta aaacattgtt agaaatcgat ttgactgtcc tgttcttaat tcattttact
     3061 ataaattcat cagaaagtcg tgatttctat tgaaatgagg actttctttt tatactcatc
     3121 tgttttcaaa aagcattcta ttccatctcc gattaacgat ggactttatc acctccttct
     3181 ccagtccttg tataacatct tggagttgat tcatgacatc ttccaaagtt tgaaaggctt
     3241 tattcttaaa tccacgttta cgaatctctt tc
//
LOCUS       DAVDFK010000071         2672 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.71, whole genome shotgun sequence.
ACCESSION   DAVDFK010000071 DAVDFK010000000
VERSION     DAVDFK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.71"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            197..907
                     /gene="ccdA2"
                     /locus_tag="VUR04_001956"
     CDS             197..907
                     /gene="ccdA2"
                     /locus_tag="VUR04_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET5341791.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            927..1493
                     /locus_tag="VUR04_001957"
     CDS             927..1493
                     /locus_tag="VUR04_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET5341792.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLRELA"
     gene            1504..2616
                     /gene="msrB"
                     /locus_tag="VUR04_001958"
     CDS             1504..2616
                     /gene="msrB"
                     /locus_tag="VUR04_001958"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET5341793.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT          766 a          493 c          613 g          800 t
ORIGIN      
        1 taaaagcgca tagtatcaag actttataga actttgatac tatgcgcttt tgtgctttga
       61 cagttttttg tatagttttt gtccaagatt tctaaatcat ctgattaaat tcctattttc
      121 ccctatcatt gtccctgttt tttcgaaaat ggaaggagta taataaatct atcaataaaa
      181 tgataggagg aactttatgg gtcatatttt cttttttcta agtgtctttt tggcagggat
      241 tctatccttc ttttctcctt gtatcttacc tttgttaccg gtctatacag gggtgttact
      301 agatgataag gatggtgctc aggcttctag cggcaaattt tcaatctcag ttactagttt
      361 attacgaact ctggccttta tagcaggaat ttcctttata tttattttgt tgggctatgg
      421 agctggtttt ttaggcgatt tgctttatgc ttcttggttc caatatctta ctggggcaat
      481 tattatcctt cttggtttgc accaaatgga gattctacac tttaaggggc tttataagga
      541 aaagaggcta caactgcaag gacaggggca aaatggtaag ggctatagtc aggcattttt
      601 attgggcttg acctttagtt ttgcttggac gccttgcgtg gggccggttc tggggtctgt
      661 tttggccttg gcggcttcag gtggttcagg agcttggcag ggagctggtc tcatgttggt
      721 gtatacgctg ggcttggcgc taccattctt gcttctagct ctgacctcta gttatgtttt
      781 gaaacatttc cgaaaacttc atccctatct cggaatcctc aaaaaagtgg gtggttttct
      841 cattattgtg atgggactct tggttctgtt tggaaatgct tcaattttaa gtcaattatt
      901 tgaataaaat ggaaaggaat atcaatatga aaaaatggca aacatgtgtt cttggagcag
      961 gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt gactagtgaa caccaaacga
     1021 aagatgaaat gaagacggag cagacagcta gtaaaacaag cgcagctaaa gggaaagagg
     1081 tggctgattt tgaattgatg ggagtagatg gcaagaccta ccgtttatct gattacaagg
     1141 gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc catctgtctg gctagtcttc
     1201 cagatacgga tgagattgct aaagaagctg gtgatgacta tgtggtcttg acagtagtgt
     1261 caccaggaca taagggagag caatctgaag cggactttaa gaattggtat aagggattgg
     1321 attataaaaa tctcccagtc ctagttgacc catcaggcaa acttttggaa acttatggtg
     1381 tccgttctta cccaacccaa gcctttatag acaaagaagg caagctggtc aaaacacatc
     1441 caggattcat ggaaaaagat gcaattttgc aaactttgag ggaattagcc taggaggtgt
     1501 cttatgaatg ataagttaaa aatcttcttg ttgctaggag tattttttct agccataacc
     1561 ggtttctatg ttctattgat acgaaatgca gggcagacag atgcctcgca aattgaaaag
     1621 gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag aaattagtaa agacgcagac
     1681 ttgcacgaaa tttatctagc tggaggttgt ttctggggag tggaggaata tttctcacgc
     1741 gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg gtagaggaga aacaactaag
     1801 tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc atgtcaccta tgatgccaag
     1861 caaatttctc tcaaggaaat cctgcttcac tatttccgca ttatcaatcc aaccagcaaa
     1921 aataaacaag gaaatgatgt ggggacccag taccgtactg gtgtttatta cacagatgac
     1981 aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg ctaagaaata cgatcaacct
     2041 ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg ctgaggatta ccatcaagac
     2101 tatctcaaga aaaatccaaa tggctactgc catatcaatg ttaatcaggc ggcctatcct
     2161 gtcattgatg ccagcaaata tccaaaacca agtgatgagg aattgaaaaa gaccctgtca
     2221 cctgaggagt atgcagttac ccaggaaaat caaacagaac gagctttctc aaaccgttac
     2281 tgggataaat ttgaatccgg tatctatgtg gatatagcaa ctggggaacc tctcttttca
     2341 tcaaaagaca aatttgagtc tggttgtggc tggcctagtt ttacccaacc catcagtcca
     2401 gatgttgtca cctacaagga agataagtcc tacaatatga cgcgtatgga agtgcggagc
     2461 cgagtaggag attctcacct tgggcatgtc tttacggatg gtccacagga caagggcggc
     2521 ttacgttact gtatcaatag cctctctatc cgctttattc ccaaagacca aatggaagaa
     2581 aaaggctacg cttatttact agattatgtt gattaatact cttcgaaaat ctcttcaaac
     2641 cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVDFK010000072         2535 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.72, whole genome shotgun sequence.
ACCESSION   DAVDFK010000072 DAVDFK010000000
VERSION     DAVDFK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.72"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VUR04_001959"
     CDS             <1..559
                     /locus_tag="VUR04_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5341794.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNISIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VUR04_001960"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VUR04_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET5341795.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDNLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2032
                     /locus_tag="VUR04_001961"
     CDS             1424..2032
                     /locus_tag="VUR04_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5341796.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(1980..>2535)
                     /locus_tag="VUR04_001962"
     CDS             complement(1980..>2535)
                     /locus_tag="VUR04_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5341797.1"
                     /translation="NIPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIK
                     PLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGG
                     FIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSDLLIPLA
                     PFEEQELITQKVEKLFEKVNQLWK"
BASE COUNT          893 a          380 c          422 g          840 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt tctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctgactttta ttggtcatga taatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaacaaa gacgaaacaa cctcttatcc
     1501 tatatatgaa atcccagaag catggagata tattaaattt gctagcctag ttaacttcag
     1561 aataggaaaa actcctccac gcagtgaagc tactttttgg ggaactgaaa taccctgggt
     1621 atctatatca gatatgccta tatctggtta tgtaactaat acgagagaat ctatttctaa
     1681 attagcatta aaatcaaaga aaatagacat ttcacctaaa ggaactttat taatgagttt
     1741 taaattatct attggaaaag ttgccatatt ggatattcct gccactcata atgaagccat
     1801 tatatcgata ttcccctatg ctaacaaaga aaatattatc agagattact taatgatatt
     1861 tttgccactt atctctactt taggtgattc aaaagatgct atcaaaggga aaacattaaa
     1921 tagtaccagt atctccgaat tattaatccc tatttctaat catgaagaga tgaaaagaat
     1981 catttccaaa gttgatttac tttttcaaaa agtttctcaa ctttttgagt aataagttcc
     2041 tgttcctcaa aaggagctaa cggaattaat agatcgctta gtgtagtttt aggaatatta
     2101 tataaagctt gacctgatag tttagttatt gctttcaatt gtttataaaa taacggagag
     2161 gacaagttaa ataatagaaa ttttgaaata atctctgaac tttcgaatgg tgttaattgg
     2221 aaaataaatc caccagccac aacaccatca tagtctttat cgattcttgc aaactttcca
     2281 atatgttcta aagaggttga cacaggtgtt attagctgat tatgttttaa ataaacttgc
     2341 tcagaggaga tgaattgtgt atcaatgtag taatcgttat ccaacagaga aaattctaaa
     2401 ggcttaatat taccaccacg tataattcta acacctttat tattaatgct taaatcgccc
     2461 ttcttgtaag aaagacctgt attcattgaa aaaatatctt ttatttttat aacaacccaa
     2521 ttcataggta tattc
//
LOCUS       DAVDFK010000073         2439 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.73, whole genome shotgun sequence.
ACCESSION   DAVDFK010000073 DAVDFK010000000
VERSION     DAVDFK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.73"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..850)
                     /locus_tag="VUR04_001963"
     rRNA            complement(<1..850)
                     /locus_tag="VUR04_001963"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(975..1047)
                     /locus_tag="VUR04_001964"
     tRNA            complement(975..1047)
                     /locus_tag="VUR04_001964"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1012..1014),aa:Ala,seq:tgc)
     gene            complement(1099..>2439)
                     /locus_tag="VUR04_001965"
     rRNA            complement(1099..>2439)
                     /locus_tag="VUR04_001965"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          523 a          732 c          512 g          672 t
ORIGIN      
        1 cggagagaac cagctatctc caagttcgtt tggaatttct ccgctaccca caagtcatcc
       61 aagcactttt caacgtgccc tggttcggtc ctccagtgcg tcttaccgca ccttcaacct
      121 gctcatgggt aggtcacatg gtttcgggtc tacgtcatga tactaaggcg ccctattcag
      181 actcggtttc cctacggctc cgtctcttca acttaacctc gcatcataac gtaactcgcc
      241 ggttcattct acaaaaggca cgctctcacc cattaacggg ctcgaacttg ttgtaggcac
      301 acggttttag gttctatttc actcccctcc cggggtgctt ttcacctttc cctcacggta
      361 ctggttcact atcggtcact agggagtatt tagggttggg agatggtcct cccagattcc
      421 gacgggattt cacgtgtccc gccgtactca ggatactgct aggtacaaag actattttaa
      481 atacgaggct attactctct ttggctgatc ttcccaaatc attcttctat aatctttgag
      541 tccacattgc agtcctacaa ccccgaagag taaactcttc ggtttgccct tctgccgttt
      601 cgctcgccgc tactaaggca atcgcttttg ctttctcttc ctgcagctac ttagatgttt
      661 cagttcactg cgtcttcctc ctcacatcct taacagatgt gggtaacagg tactacctgt
      721 tgggttcccc cattcggaaa tccctggatc atcgcttact tacagctacc caaggcatat
      781 cgtcgtttgt cacgtccttc gtcggctcct agtgccaagg catccaccgt gcgcccttat
      841 taacttaacc ttattttctg acctttcagt cataaactct tattaatact acagcgtttt
      901 cggtttattt tcttgttact atttgatata gatattcaat tttcaatgtg cattacttgg
      961 tgatctctca ccaatggagc ctagcgggat cgaaccgctg acctcctgcg tgcaaagcag
     1021 gcgctctccc agctgagcta aggccccaca agacctctca agactaaaca agaccaatgc
     1081 gcagttcctt atccttagaa aggaggtgat ccagccgcac cttccgatac ggctaccttg
     1141 ttacgacttc accccaatca tctatcccac cttaggcggc tggctcctta cggttacctc
     1201 accgacttcg ggtgttacaa actctcgtgg tgtgacgggc ggtgtgtaca aggcccggga
     1261 acgtattcac cgcggcgtgc tgatccgcga ttactagcga ttccgacttc atgtaggcga
     1321 gttgcagcct acaatccgaa ctgagactgg ctttaagaga ttagcttgcc gtcaccggct
     1381 tgcgactcgt tgtaccagcc attgtagcac gtgtgtagcc caggtcataa ggggcatgat
     1441 gatttgacgt catccccacc ttcctccggt ttattaccgg cagtctcgct agagtgccca
     1501 actaaatgat ggcaactaac aataggggtt gcgctcgttg cgggacttaa cccaacatct
     1561 cacgacacga gctgacgaca accatgcacc acctgtcacc tctgtcccga aggaaaactc
     1621 tatctctaga gcggtcagag ggatgtcaag acctggtaag gttcttcgcg ttgcttcgaa
     1681 ttaaaccaca tgctccaccg cttgtgcggg cccccgtcaa ttcctttgag tttcaacctt
     1741 gcggtcgtac tccccaggcg gagtgcttaa tgcgttagct acggcactaa accccggaaa
     1801 gggtctaaca cctagcactc atcgtttaca gcgtggacta ccagggtatc taatcctgtt
     1861 tgctccccac gctttcgagc ctcagcgtca gttacaagcc agagagccgc tttcgccacc
     1921 ggtgttcctc catatatcta cgcatttcac cgctacacat ggaattccac tctcccctct
     1981 tgcactcaag ttaaacagtt tccaaagcct actatggtta agccacagcc tttaacttca
     2041 gacttatcta accgcctgcg ctcgctttac gcccaataaa tccggacaac gctcgggacc
     2101 tacgtattac cgcggctgct ggcacgtagt tagccgtccc tttctggtaa gataccgtca
     2161 cagtgtgaac tttccactct cacactcgtt cttctcttac aacagagctt tacgatccga
     2221 aaaccttctt cactcacgcg gcgttgctcg gtcagacttc cgtccattgc cgaagattcc
     2281 ctactgctgc ctcccgtagg agtctgggcc gtgtctcagt cccagtgtgg ccgatcaccc
     2341 tctcaggtcg gctatgtatc gtcgccttgg tgagccgtta ccccaccaac tagctaatac
     2401 aacgcaggtc catctggtag tgatgcaagt gcacctttt
//
LOCUS       DAVDFK010000074         2247 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.74, whole genome shotgun sequence.
ACCESSION   DAVDFK010000074 DAVDFK010000000
VERSION     DAVDFK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2247
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.74"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..883
                     /locus_tag="VUR04_001966"
     CDS             <1..883
                     /locus_tag="VUR04_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5341798.1"
                     /translation="VMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDI
                     VDRVFLIDKGKLKKTYTRREFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNL
                     SYKFTDDECLSLKDISFKLGKIYGIIGSNGRRKSTLLRCLIGLEKKSKEEIYFKGEKL
                     SKKERLKNSSLVMQDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLCLDEFIERHP
                     MSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIV
                     SHDIEFLNEVADEIFEL"
     gene            complement(1566..2118)
                     /locus_tag="VUR04_001967"
                     /pseudo
     CDS             complement(1566..2118)
                     /locus_tag="VUR04_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          791 a          337 c          394 g          725 t
ORIGIN      
        1 agttatggat gagccttcat cgaatttaga tattaaaagc ataagtgttt tggcaaagat
       61 gctaaagata ttaaaagaga aaggcataag cataattgtt gcagagcaca gaatttatta
      121 tttgatggac atagttgacc gtgtattttt aatagataaa ggaaagctta aaaaaactta
      181 tactagaagg gaatttttaa agctagataa aaatgaatta aatgctttaa gtttaagaga
      241 taaagaatta agtaaattaa aagttcctta tttaaaagaa ggtggagagt atcagataaa
      301 aaatcttagc tacaaattta ctgatgatga gtgtttaagc ttaaaagata tttcgttcaa
      361 gcttgggaaa atttatggca taataggatc caacggacga agaaaatcaa cgcttttaag
      421 atgtttaata ggtcttgaga aaaaatcaaa agaagaaatt tattttaagg gagagaagct
      481 atctaaaaaa gaaagactca aaaactcttc acttgttatg caagatgtaa atcatcaatt
      541 attcacagat gaagtattca acgagcttag attaggagta aagaattttg atgaagaaaa
      601 ggcgaaaatc attttaaaag atttatgcct ggacgaattt attgaaaggc atccgatgag
      661 tttatcagga gggcaaaagc aaaggcttgc aatagcatct gttatgtgca agaattctcc
      721 atttgtcttt tttgacgaac cttcaagtgg tatggattat tccaatatga taaaaatatc
      781 tgaactgatt aataagtata aaaccatgga taaaataatt tttattgttt cccatgatat
      841 agaattttta aatgaagtgg cagatgaaat ttttgaattg taaaatagag tctgttaaac
      901 atgtctatag aactggtaaa ttgtctaaaa atttaaaaga tactaacaca tattgatatt
      961 tattagaaaa ttaacttcag gatttttaca gtatttataa actttataat atgtatttat
     1021 agtattaata atttccatat ctttagggaa attctttatt tacttaccat aattaaagag
     1081 atgagagata aatatcggca gtcttcggac tgcctttatt tttttactta atttaatgca
     1141 gtaaatcata cgattgaaag gaatctgcgt tatatgctat aattagatag ttaatctata
     1201 catttagaaa ggtaaaatat agaattggag aatgatatgg gattttcata taataaattg
     1261 taaccgccca ataacgaagt atattgaaaa atctccagac tagagaactc atatatagtt
     1321 cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca cggtaaatag
     1381 gcctctaaaa cctctttgtt tacgagagtt tcctcgtttg gaagacattc tagaagatag
     1441 gatagatatt tctcactatt tataatggat tgaaataaga tatgaacaaa tcgattagga
     1501 aaggaaaatt gatttataga aatattttag cagtcgatgc gtactgttat agattcaacg
     1561 cactataatt gatgacgttt agctgtttcc aacaaactca taataatagc tcttgcttta
     1621 gctccttcaa aactttgaga aaataaccac cctcgctttt taaaatttag cttaggctaa
     1681 aagagtccac tgaactcttt tactccgtcc cataaccaat gatttaatgg tgcgtttagc
     1741 tagattattg gaaaggacca gatgtccgtt tttcaaaata gtcttaaagt tttcttcata
     1801 cttgaggctg tattcaattg cccttcctgg ttttgaacct gctaaaactg actgacggcg
     1861 gcaccaagca aagaagtctt ccattaaggg ctggagatgt tcttgacgtt tctgtagtcg
     1921 ttcatcagct ggcaaagcct cccagtctct tttcaaggca aataactggt cacaataggc
     1981 taaaccttta gctcctaagg atgatttatc cgcttgcttg ggggtcgctt caaaaaattt
     2041 ccttctcaca tgcgtccaac atccaacaag ttcagcttct tccagttgac gataagcttc
     2101 tagcggttcg cagtttacca agcttagcgt cgccttactc ctaaactttg gactgctatc
     2161 gcataggcag aactagagga ctaaagtcct aagttactgc cgcaacatgt cacaatgcac
     2221 atagccagaa taatctccta ggaattc
//
LOCUS       DAVDFK010000075         2022 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.75, whole genome shotgun sequence.
ACCESSION   DAVDFK010000075 DAVDFK010000000
VERSION     DAVDFK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.75"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..2009
                     /locus_tag="VUR04_001968"
     rRNA            <1..2009
                     /locus_tag="VUR04_001968"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          562 a          414 c          595 g          451 t
ORIGIN      
        1 tagagcactg tttgggtgag gggtccatcc cggattacca atctcagata aactccgaat
       61 gccaatgaat tatggtcggc agtcagactg cgagtgctaa gatccgtagt cgaaagggaa
      121 acagcccaga ccaccagcta aggtcccaaa ataattgtta agtggaaaag gatgtggggt
      181 tgcacagaca actaggatgt tagcttagaa gcagctattc attcaaagag tgcgtaatag
      241 ctcactagtc gagtgaccct gcgccgaaaa tgtaccgggg ctaaaacaat ttaccgaagc
      301 tgtggatacc tttataggta tggtaggaga gcgttctatg tgtgatgaag gtataccgtg
      361 aggagtgctg gaacgcatag aagtgagaat gccggtatga gtagcgaaag acaggtgaga
      421 atcctgtcca ccgtaagact aaggtttcca ggggaaggct cgtccgccct gggttagtcg
      481 ggacctaagg agagaccgaa aggtgtatcc gatggacaac aggttgatat tcctgtacta
      541 gagtatgtag tgatggaggg acgcagtagg ctaactaaag cagacgattg gaagagtctg
      601 tctaagcagt gaggtgtgaa ttgagtcaaa tgcttaattc tataacattg agctgtgatg
      661 gggagcgaag tttagtagcg aagttagtga cgtcacactg ccaagaaaag cttctagcgt
      721 ttaaacatac tctacccgta ccgcaaaccg acacaggtag tcgaggcgag tagcctcagg
      781 tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt cgggagaagg
      841 ggtgctgact ttaagtcagc cgcagtgaat aggcccaagc aactgtttat caaaaacaca
      901 gctctctgct aaatcgtaag atgatgtata gggggtgacg cctgcccggt gctggaaggt
      961 taagaggagt gcttagcgta agcgaaggta tgaattgaag ccccagtaaa cggcggccgt
     1021 aactataacg gtcctaaggt agcgaaattc cttgtcgggt aagttccgac ccgcacgaaa
     1081 ggcgtaatga tttgggcact gtctcaacga gagactcggt gaaattttag tacctgtgaa
     1141 gatgcaggtt acccgcgaca ggacggaaag accccatgga gctttactgc agtttgatat
     1201 tgagtgtctg taccacatgt acaggatagg taggagtcta agagatcggg acgccagttt
     1261 cgaaggagac gctgttggga tactaccctt gtgttatggc cactctaacc cagataggtg
     1321 atccctatcg gagacagtgt ctgacgggca gtttgactgg ggcggtcgcc tcctaaaagg
     1381 taacggaggc gcccaaaggt tccctcagaa tggttggaaa tcattcgcag agtgtaaagg
     1441 tataagggag cttgactgcg agagctacaa ctcgagcagg gacgaaagtc gggcttagtg
     1501 atccggtggt tccgtatgga agggccatcg ctcaacggat aaaagctacc ctggggataa
     1561 caggcttatc tcccccaaga gttcacatcg acggggaggt ttggcacctc gatgtcggct
     1621 cgtcgcatcc tggggctgta gtcggtccca agggttgggc tgttcgccca ttaaagcggc
     1681 acgcgagctg ggttcagaac gtcgtgagac agttcggtcc ctatccgtcg cgggcgtagg
     1741 aaatttgaga ggatctgctc ctagtacgag aggaccagag tggacttacc gctggtgtac
     1801 cagttgtctt gccaaaggca tcgctgggta gctatgtagg gaagggataa acgctgaaag
     1861 catctaagtg tgaaacccac ctcaagatga gatttcccat gattatatat cagtaagagc
     1921 cctgagagat gatcaggtag ataggttaga agtggaagtg tggcgacaca tgtagcggac
     1981 taatactaat agctcgagga cttatccaaa gtaactgaga at
//
LOCUS       DAVDFK010000076         1960 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.76, whole genome shotgun sequence.
ACCESSION   DAVDFK010000076 DAVDFK010000000
VERSION     DAVDFK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.76"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..237
                     /locus_tag="VUR04_001969"
     CDS             <1..237
                     /locus_tag="VUR04_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341799.1"
                     /translation="YNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQ
                     GITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            313..865
                     /locus_tag="VUR04_001970"
                     /pseudo
     CDS             313..865
                     /locus_tag="VUR04_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1448..1924
                     /locus_tag="VUR04_001971"
     CDS             1448..1924
                     /locus_tag="VUR04_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5341800.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
BASE COUNT          642 a          337 c          388 g          593 t
ORIGIN      
        1 tataacctct tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct
       61 tatagggtgc tagagagtga tagtcagctg acctactatt ggaccttttt gtcaggtaaa
      121 tcagagaaac aagggattac gctttaccac catgatcagt gtcgaagtgg ttcagtagta
      181 caagaattcc taggagatta ttctggctat gtgcattgtg acatgttgcg gcagtaactt
      241 aggactttag tcctctagtt ctgcctatgc gatagcagtc caaggtttag gagcaaggcg
      301 acgctaagct tggtaaactg cgaaccgcta gaagcttatc gtcaactggc agaagctaaa
      361 cttgttggat gttgggcgca tgtgagaagg aaattttttg aagcgacccc caagcaagca
      421 gataaatcat ccttaggagc taaaggttta gcttattgtg atcagttatt ttccctggaa
      481 agagactggg aggctttgcc agctgatgaa cgactacaga aacgtcaaga acatctccag
      541 cccttaatgg aagacttctt tgcttagtgc cggcgtcagt cagttttagc aggttcaaaa
      601 ctaggaaggg caattgaata cagcctcaag tataaagaaa cctttaagac tattttaaaa
      661 gacggacatc tggtcctttc caataatcta gctgaacgcg ccattaaatc attggttatg
      721 ggacggagta aaagagtcca gtggactctt ttagcctaag ctaaatttta aaaagcgagg
      781 gtggttattt tctcaaagtt ttgaaggagc taaagcaaga gctattatta tgagtttgtt
      841 ggaaacagct aaacgtcatc aattatagtg cgttgaatct ataacagtac gcatcgactg
      901 ctaaaatatt tctataaatc aattttcctt tcctaatcga tttattcata tcttatttca
      961 atccattata aatagcgaga aatatctatc ctatcttcta gaatgtcttc taaacgtgga
     1021 aactctcgta aacaaagagg ttttagaggc ttatttacca tggactaaag ttgtacaaga
     1081 aaagtgaaaa taagaaatct ccagattagg agctatccgt gagttcacta atctggagat
     1141 ttttcaatag acttcgttat tggacggtta cgatatgatc actgacttcg tcagttctat
     1201 ctacaaccta aaaacagtgt tttgaacaac ctgcggctag cttcctagtt tgctctttga
     1261 ttttcattga atattagaac agcaaaaatg cttggagtat ttgtttgtgt gtttgttttt
     1321 atataacaaa ctataaacaa aacaaaaata taaaaaaaga gacaaaaaag aacaaaaagt
     1381 aattgacaac ggtttcatat agtgttatac ttatggcata aagttaatgg aaagaaggga
     1441 aaaacttatg gtattagatt atttctttga caaaaacctt gtgttttgct tagaagcgga
     1501 taatcaagaa caactctttg atcaggttgc aactttattg gaagaacgag aaattgtcac
     1561 tccaacttat cgtgaagcct tgatcacgcg tgaaaagtca tttccaactg gtttagatat
     1621 ggaatttcta ggaaaggact tgccaaatgt agcgattcct catacagata ttgttcataa
     1681 tctagctgag aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc acaatatgat
     1741 agctcctgat aaggaagtag aagtatccct actcttcttt attattaaca attcaagttc
     1801 aagtcaaaca aatattctgg ctcagttgat ggactttttc acaggaaatg gacatcttga
     1861 agatttatca aaaatttccg aaccagaaaa actttatgct tacattgctg aagcaaccgc
     1921 ttaatcttgt ctattaaaaa ataaaatcgg aggaaatcca
//
LOCUS       DAVDFK010000077         1954 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.77, whole genome shotgun sequence.
ACCESSION   DAVDFK010000077 DAVDFK010000000
VERSION     DAVDFK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.77"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..552)
                     /locus_tag="VUR04_001972"
     CDS             complement(<1..552)
                     /locus_tag="VUR04_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5341801.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKIHHDLPIEEIRDMLEVVIYIRQHGAGELSDHTEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQR"
     gene            1189..1569
                     /locus_tag="VUR04_001973"
     CDS             1189..1569
                     /locus_tag="VUR04_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET5341802.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGCNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
BASE COUNT          625 a          248 c          397 g          684 t
ORIGIN      
        1 gcgttgcaat atttttccag tgatgagatg gaggtattca atgggaaaac tgaaaagaat
       61 ggtattgagg atttttagat cactctcata ccatgtatct tgtttttcaa tttttctcca
      121 aagttttttg acaacctgtt ctgtgtgatc tgatagttcc cctgccccgt gttgacggat
      181 ataaatgaca acttcaagca tatctctgat ttcttctata gggagatcgt ggtggatctt
      241 gaggtagtct tggcattttt gaaataaatt gacaagatcg ctggtcccga taatggaacg
      301 catattgaga taggtttgca taatctctgt gcgttgactt ggttgataaa gttgacagat
      361 atattcaaac tcttcaaaac tcatattgat ttgacggaga agaaattcca tattttcata
      421 ttttggggtt gtcttgccac tttcgatttt tgataagctg gttcttgaga gaacaccccc
      481 acagacctct tcttgggtca gcccctttga ctcacgtatt tctttataga cctttccgaa
      541 atcataacgc atgattttct ccttttcgtg aaaaaagtta acaaacaata aaattttgtt
      601 aaaaatattg tatcatagca atgtaaaaag taaaaaagaa agtcgaaata aatttgtgaa
      661 aaaagttaac gtaattttaa aatgagctta ataagaggta ctatgtaggt agaaaataaa
      721 gataggagaa aaagtatgaa taaaaaaata ttttgtattc tagtatgtat tatattattg
      781 attagtctgg ctataatctt tccatggggc tggtcgatat aatgtaaggg agcttgagtt
      841 gttagtagag gataaaatgt taagagtaat agtagttatt caatctttag taataatact
      901 gcttgccgtt gctttattat tatctcggaa aaactttgat tcgttaaatg ttgttcttat
      961 aatgatgatc gtatcacaat tgttgttatt agtatatttg ataaaatcag ggaatcagtg
     1021 attagctgtt atttgaatta agtaaactgt taagcttcaa gcagtaactg gttttaaata
     1081 tttaaaataa gataaaggaa ggaagtctaa tttaggtaac taaacaaagc ctgcgatcac
     1141 ttgttaggaa accatcctaa ccatgcttaa taaaaaagga gaaaataaat ggaactagta
     1201 ttaccaaata attatgttgc tcttgagcaa gaagagatga tgtatcttga tgggggtggt
     1261 gttggttgta actggtggaa tagtagaggt agttttgcaa cagttctgga tgtaggtttg
     1321 gccatctata gtggtggtgc aacaatttat tctgcttatg cgataaaaaa agctatctca
     1381 gctaatagag gggctattac gagaacatta cgtagtttaa taattaaaca tgtaggtagt
     1441 gcagctggcc atttagtcaa tactgcacta aacgttgcac taactgttac tggattttca
     1501 ctaggtggag caatcgcata tggggctgat tgggctgacg gtagcttaga tggttatatt
     1561 tttgcttaaa atgaaacatt tttttgcagg aattggtgaa ataaactttg taagttattt
     1621 attgtatata tgtgtaggaa tagccccttt ttttcacgta tatataatag gttctgaaat
     1681 gaattttgtg aaaatagtgt tatctatttt gggaattata tttgtttgta ttttaactat
     1741 tgctcgaatt tataggactt ttttctataa agaatagttt ggacttgaaa tgtatttaaa
     1801 aacaagaggt tggtagatta tcagcctctt tcttgtcgtt gaaaaagtga gatatattga
     1861 cttttgaaaa aaatgtcata attgagttgg gataaacgta aaagtcatac tttctcgtta
     1921 aatcgttcgg cgatcctatg aaaaggtcga ggag
//
LOCUS       DAVDFK010000078         1685 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.78, whole genome shotgun sequence.
ACCESSION   DAVDFK010000078 DAVDFK010000000
VERSION     DAVDFK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.78"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            114..1589
                     /locus_tag="VUR04_001974"
     CDS             114..1589
                     /locus_tag="VUR04_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET5341803.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          473 a          343 c          340 g          529 t
ORIGIN      
        1 ccagcaatga gcgctccagt atttgacaat attgaatcag ctattaaaga acacggatta
       61 agctaattct aatttgttaa cattcatata acataaaaaa gggaggaact gttatggatg
      121 caatctttga cctaatcgga aaggttttca atcccatctt agaaatgggt ggacctgtca
      181 tcatgttaat cattttgaca gtattggctt tactttttgg agtgaaattc tccaaagcgc
      241 ttgaaggtgg tatcaaactt gccatcgctc ttacaggtat cggtgctatc atcggtatgc
      301 taaatggtgc tttctcagca tcacttgcaa aattcgttga aaacactggt atccaattga
      361 gtattaccga cgttggttgg gcaccactcg caacaatcac ttggggttct gcttggacac
      421 tatacttctt gctcatcatg ttgattgtca acgtagtgat gcttgctatg aagaaaaccg
      481 atacacttga tgtcgatatc tttgatatct ggcacttgtc tatcacaggt ctcttgatta
      541 aatggtatgc tgataacaat ggtgtgagtc aaggggtttc actctttatt gctacagcag
      601 ctatcgtcct tgtcggtgtg ttgaaaatta tcaactctga cttgatgaaa cctacatttg
      661 atgaccttct taacgcccca agttcatcac caatgacatc aactcacatg aactacatga
      721 tgaacccagt tatcatggtt ttggataaga tttttgaaaa attcttccca ggccttgata
      781 aatatgactt tgatgctgct aaattgaaca agaaaatcgg tttctgggga tctaaattct
      841 tcatcggttt catccttggt atcgttatcg gtattatggg aactccacat ccaattgcag
      901 gtgttgcaga tgcagataaa tggcgtcttg ttatcaaagg atggttgtct cttggtttga
      961 ctgccggtgt atctttggaa ctcttctcac ttatcggttc atggttcatc gcagccgtag
     1021 aaccactatc acaaggtatt acaaacgttg ctactaaacg tcttcaagga cgtaaattca
     1081 atatcggtct tgactggcca ttcatcgctg gtcgtgctga aatctgggct tgtgccaacg
     1141 tacttgcacc aatcatgttg attgaagcag tgcttctttc aaaagttgga aatggtatct
     1201 tgccacttgc aggtatcatc gctatgggtg ttactccagc tctcttggtt gtaactcgtg
     1261 gtaaattgct ccgtatgatt atcttcggaa cactcttgtt gccactcttc cttctttcag
     1321 gtacacttat tgcaccattt gcaacagaac ttgctaaagg tgtaggtgcc ttcccagaag
     1381 gtgtgagcca aactcaattg attactcact ctactcttga aggaccaatc gaaaaacttc
     1441 ttggttggac aattggtaac actacaactg gtgatatcaa agcaatcctt ggtgcagtag
     1501 ccttccttgt attctatatc ggtatctttg cttggtacag aaaacaaatg atcaaacgta
     1561 acgaagagta cgcagcaaaa gcaaaataat gcgctcctat aaaatataaa ctcaatgaaa
     1621 atcaaagagc aaactaggaa gctagccgca ggttgctcaa aacacagttt tgaggttgta
     1681 gataa
//
LOCUS       DAVDFK010000079         1087 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.79, whole genome shotgun sequence.
ACCESSION   DAVDFK010000079 DAVDFK010000000
VERSION     DAVDFK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1087
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.79"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..308
                     /locus_tag="VUR04_001975"
     CDS             <1..308
                     /locus_tag="VUR04_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341804.1"
                     /translation="LYQLLLFHFQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKE
                     KVINALQLPYSNAKLEATNNLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(372..459)
                     /locus_tag="VUR04_001976"
     tRNA            complement(372..459)
                     /locus_tag="VUR04_001976"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(423..425),aa:Ser,seq:gct)
     gene            complement(466..539)
                     /locus_tag="VUR04_001977"
     tRNA            complement(466..539)
                     /locus_tag="VUR04_001977"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(503..505),aa:Ile,seq:gat)
     gene            complement(575..645)
                     /locus_tag="VUR04_001978"
     tRNA            complement(575..645)
                     /locus_tag="VUR04_001978"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(611..613),aa:Gly,seq:tcc)
     gene            complement(665..737)
                     /locus_tag="VUR04_001979"
     tRNA            complement(665..737)
                     /locus_tag="VUR04_001979"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(702..704),aa:Phe,seq:gaa)
     gene            complement(741..814)
                     /locus_tag="VUR04_001980"
     tRNA            complement(741..814)
                     /locus_tag="VUR04_001980"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(778..780),aa:Met,seq:cat)
     gene            complement(828..917)
                     /locus_tag="VUR04_001981"
     tRNA            complement(828..917)
                     /locus_tag="VUR04_001981"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(879..881),aa:Ser,seq:tga)
     gene            complement(928..1001)
                     /locus_tag="VUR04_001982"
     tRNA            complement(928..1001)
                     /locus_tag="VUR04_001982"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(965..967),aa:Ile,seq:cat)
     gene            complement(1015..1087)
                     /locus_tag="VUR04_001983"
     tRNA            complement(1015..1087)
                     /locus_tag="VUR04_001983"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1052..1054),aa:Met,seq:cat)
BASE COUNT          330 a          286 c          217 g          254 t
ORIGIN      
        1 agctctatca gctcttgctt tttcacttcc agaataagga accagagaaa tttttcgaac
       61 ttatcgagga caatcttaag caggttcatc ctatttttca gactgtcttt aaaaccttcc
      121 tcaaagataa agaaaaggtt atcaacgccc ttcaactacc ctattcaaac gccaaattgg
      181 aagcgaccaa taatctcatc aaacgcaatg cctttggttt tcgaaacttt gaaaacttca
      241 aaaaacggat ttttatcgct ctgaacatca aaaaagaaag gacgaaattt gtcctttctc
      301 gagcttagct gacttcaacc cactacagtt gacaaagagc caaaaaagag agttacaaac
      361 tctcattaaa acggagaata agggattcga acccttgcgc cagttacccg acctaacgat
      421 ttagcaaacc gtcctcttca gcctcttgag taattctcca attaatgggc acgagtggac
      481 tcgaaccacc gacctcacgc ttatcaggcg tgcgctctaa ccacctgagc tacgcgccca
      541 agttaaaaaa cttggtaatt tgaacaaagt tcaaagcggg tgacgagaat cgaactcgcg
      601 acaacagctt ggaaggctgt agttttacca ctaaactaca cccgcataaa tactatcaat
      661 aaaatggcgc gagacggaat cgaaccgccg acacatggag cttcaatcca ttgctctacc
      721 aactgagcta ccgagcctta ttgcgggagc aggatttgaa cctacgacct tcgggttatg
      781 agcccgacga gctacctagc tgctccatcc cgcgttaata atataaaagg aggatgtggg
      841 attcgaaccc acgcacgctt ttacacgcct gacggttttc aagaccgttc ccttcagccg
      901 gacttgggta atcctccaat attcaaatgg accttgtagg acttgaacct acgaccactc
      961 ggttatgagc cgagagctct aaccagctga gctaaaggtc cgacaagatc attatagcgg
     1021 cgaaggggat cgaacccccg acctcccggg tatgaaccgg acgctctagc cagctgagct
     1081 acaccgc
//
LOCUS       DAVDFK010000080          962 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.80, whole genome shotgun sequence.
ACCESSION   DAVDFK010000080 DAVDFK010000000
VERSION     DAVDFK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.80"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..>962
                     /gene="phtD"
                     /locus_tag="VUR04_001984"
     CDS             <1..>962
                     /gene="phtD"
                     /locus_tag="VUR04_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET5341805.1"
                     /translation="IFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPL
                     RYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGK
                     PNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSL
                     SEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAA"
BASE COUNT          311 a          212 c          205 g          234 t
ORIGIN      
        1 attttcgacc cagcgcaaat cacaagtcga accgccagag gtgtagctgt ccctcatggt
       61 aaccattacc actttatccc ttatgaacaa atgtctgaat tggaaaaacg aattgctcgt
      121 attattcccc ttcgttatcg ttcaaaccat tgggtaccag attcaagacc agaacaacca
      181 agtccacaat cgactccgga acctagtcca agtctgcaac ctgcaccaaa tcctcaacca
      241 gctccaagca atccaattga tgagaaattg gtcaaagaag ctgttcgaaa agtaggcgat
      301 ggttatgtct ttgaggagaa tggagtttct cgttatatcc cagccaagga tctttcagca
      361 gaaacagcag caggcattga tagcaaactg gccaagcagg aaagtttatc tcataagcta
      421 ggagctaaga aaactgacct cccatctagt gatcgagaat tttacaataa ggcttatgac
      481 ttactagcaa gaattcacca agatttactt gataataaag gtcgacaagt tgattttgag
      541 gctttggata acctgttgga acgactcaag gatgtctcaa gtgataaagt caagttagtg
      601 gatgatattc ttgccttctt agctccgatt cgtcatccag aacgtttagg aaaaccaaat
      661 gcgcaaatta cctacactga tgatgagatt caagtagcca agttggcagg caagtacaca
      721 acagaagacg gttatatctt tgatcctcgt gatataacca gtgatgaggg ggatgcctat
      781 gtaactccac atatgaccca tagccactgg attaaaaaag atagtttgtc tgaagctgag
      841 agagcggcag cccaggctta tgctaaagag aaaggtttga cccctccttc gacagaccat
      901 caggattcag gaaatactga ggcaaaagga gcagaagcta tctacaaccg cgtgaaagca
      961 gc
//
LOCUS       DAVDFK010000081          874 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.81, whole genome shotgun sequence.
ACCESSION   DAVDFK010000081 DAVDFK010000000
VERSION     DAVDFK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.81"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            362..838
                     /locus_tag="VUR04_001985"
     CDS             362..838
                     /locus_tag="VUR04_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5341806.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMKFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
BASE COUNT          301 a          143 c          152 g          278 t
ORIGIN      
        1 agtaaagcag gcttagatgg tctgcttttt tagtttttat actcttcgaa aatctcttca
       61 aaccacgtca gcgtcgcctt accgtatgta tggttactga cttcgtcagt ttcatctaca
      121 acctcaaaac catgttttga gtaacctgcg gctagcttcc tagtttgctc tttgattttc
      181 attgagtatt agaacagaaa aatgcttgga gtatttgttt gtgtgtttat ttttatataa
      241 caaactataa acaaaacaaa aatataaaaa aagagacaaa aaagaataga aagtaattaa
      301 caacgatttc atatagtgtt atacttatag cataaagtta atggaaagaa gggaaaacct
      361 tatggtatta gattatttct ttgacaaaaa ccttgtgttt tgcttagaag cggataatca
      421 agaacaactc tttgatcagg tagcaagctt gttggaagaa cgagaaattg tcactcctac
      481 ttatcgtgaa gccttgatca cgcgtgaaaa gtcatttcca actggtttag atatgaaatt
      541 tctaggaaag gacttgccaa atgtagcgat tcctcacaca gatattgttc ataatctagc
      601 tgagaaagtg gtggttgttc gattagaaaa accagtaact tttcacaata tgatagctcc
      661 tgataaggaa gtagaagtat ccctactctt ctttatcatt aacaattcaa gttcaagtca
      721 aacaaatatt ctggctcagt tgatggactt tttcacagga aatggacatc ttgaagacct
      781 atcaaaaatt tccgaaccag aaaaacttta tgcttatata gatgaagcaa tcgcttaatc
      841 ttgtctatta aaaaataaaa tcggaggaag tcta
//
LOCUS       DAVDFK010000082          784 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.82, whole genome shotgun sequence.
ACCESSION   DAVDFK010000082 DAVDFK010000000
VERSION     DAVDFK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.82"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..499
                     /locus_tag="VUR04_001986"
                     /pseudo
     CDS             1..499
                     /locus_tag="VUR04_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          262 a          112 c          153 g          257 t
ORIGIN      
        1 agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgacga
       61 aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag gtcagttaag
      121 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
      181 tggtgaatta atcgttccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      241 ttggtttcag aagtttttct taccaacatt aaccacacca tcggttatta ttatggataa
      301 tgcaagattc catagaatgg gtaagttaga actcttgtgt gaagagtttg ggtataaact
      361 tttacctctt cctccctact cgcctgagta caatcctatt gagaaaacat gggctcatat
      421 caaaaagcac ctcaaaaggg tattaccaag ttgcaatacc ttttatgagg ctcttttgtc
      481 ctgctcttgt ttcaattgac tataaatcgc tataagaaaa aatcatttta ttggtataaa
      541 gaagtgattg aaagtaatgg cgaaacctta tatgattagt tcataaaaaa caagtttaga
      601 ttcttatcta agcttgtttt tgaaaacttt agggataatt ttggaagata tgagatgaca
      661 ttgactattc atgtatatta taaaggcgat ggagattgtg caataaagtt tgtaagagaa
      721 atgcttgaat ctgggcttgt cgcagaaatt agatgtcaaa aaggtaattt gaaatacgaa
      781 tatt
//
LOCUS       DAVDFK010000083          715 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.83, whole genome shotgun sequence.
ACCESSION   DAVDFK010000083 DAVDFK010000000
VERSION     DAVDFK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.83"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..>715
                     /locus_tag="VUR04_001987"
     CDS             <1..>715
                     /locus_tag="VUR04_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET5341807.1"
                     /translation="YRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLE
                     RFNQLLFRMDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTIL
                     PHSAYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGR
                     GQAENFIKEMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIK
                     RFRHLFLHVVGKCVRTGRK"
BASE COUNT          202 a          163 c          144 g          206 t
ORIGIN      
        1 actatcgtgc tcatggctat catcctcttt atgctttcga ggggaagaca ggttattgtt
       61 tcaatgccca gcttcgtcct ggtaatcgtt attgttctga agaggcagac agctttatca
      121 cacctgtttt agaacggttt aatcaacttc tctttcgaat ggatagtggc tttgcgaccc
      181 caaaattata cgatttaatt gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa
      241 atactgttct gagccgtctt ggagaccttt ccctcccttg cccacaggat gaggacttaa
      301 ccatcttgcc ccactccgcc tactcagaaa ctctctatca agcaggatct tggtcgcaca
      361 agcgtcgtgt ctgccagttc tctgaacgaa aagaaggaaa cttgttctac gatgttattt
      421 ctctcgttac aaatatgacg agtggaacaa gccaagacca gtttcagctt tatcgtggac
      481 gtggtcaagc cgagaatttc atcaaggaga tgaaggaggg attttttggc gataaaacgg
      541 atagttcaac cttaatcaaa aacgaagttc gtatgatgat gagctgtatc gcctacaatc
      601 tctatctttt tctcaaacat ctagctggag gtgacttcca aactttaaca atcaaacgct
      661 tccgccatct ttttcttcac gtggtaggaa aatgtgttcg aacaggacgc aagca
//
LOCUS       DAVDFK010000084          703 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.84, whole genome shotgun sequence.
ACCESSION   DAVDFK010000084 DAVDFK010000000
VERSION     DAVDFK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.84"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..>703
                     /locus_tag="VUR04_001988"
     CDS             <1..>703
                     /locus_tag="VUR04_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5341808.1"
                     /translation="NYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTIHTE
                     IKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQKFS
                     PEMMVMAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQSIE
                     QRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQAL
                     KLILKQHKILSITADN"
BASE COUNT          246 a          143 c          146 g          168 t
ORIGIN      
        1 aattatacta caaaagccaa acatttgaca atcgatagcc gtcgcttaat cgaaagatgg
       61 aaaaaagaag gaaaatcaaa tagagaaatt gcctctctac ttggaaaagc tcctcaaact
      121 atccacactg aaatcaagcg tgggacagtc cgacaatgtc ttggaaaagg gcgcttcaaa
      181 gaggtttatt ctgccgacta tgctcaacag tcttatgaaa acaatcgcaa gcgctcggtc
      241 aagaaatcaa gcttgaccaa ggaactaaag gaaaagattc tccactatca taaccaaaaa
      301 ttttcgcctg aaatgatggt gatggctaaa ggggttaacg tgggaatttc aaccatttac
      361 tattggattc atcgtggaaa attggggtta agcaagcagg atctgcttta ccctagaaaa
      421 ggaaaagcgc ttaagaaaca ggctagcacc aactttaaac ctgctggtca atccatcgaa
      481 cagcggcctg aagctatcaa tcttcgcttg gagaatgggc attatgagat tgatacggtt
      541 ctacttacga gagcgaaaaa ctactgcttg cttgtcttga cggatcgaaa gagtagacat
      601 cagatcatcc gattgattcc aaataaaagt gctgaggtgg tcaatcaggc tctaaaactc
      661 atcttaaaac aacacaagat tctttccatc acggcagata atg
//
LOCUS       DAVDFK010000085          640 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.85, whole genome shotgun sequence.
ACCESSION   DAVDFK010000085 DAVDFK010000000
VERSION     DAVDFK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.85"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..640
                     /locus_tag="VUR04_001989"
                     /pseudo
     CDS             1..640
                     /locus_tag="VUR04_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          197 a          123 c          142 g          178 t
ORIGIN      
        1 atagagcttt tagactgtaa tcaaacaacg atttggcgaa atgtaaaaaa atatgaggag
       61 ttcggactcg actctctcct tcaagaaaca cgtggtggtc gtaaccatgc atatatgaca
      121 gttgaggaag agaaagcctt tcttgctcgc catttgaagg ctgcagaggc aggagaattt
      181 gttacaattg atgccttatt tcaggcttat aaaaaggagt taggtcgttc ctacacacgt
      241 gatgccttct atcaactgtt gaagcgccat ggttggcgaa atattacgcc acgtccagaa
      301 catcctagga aagcagacgc tcaaaccatt gtcgcgtcta aaaataaaat ctcaattcaa
      361 gaagacaaga aagcgcttta aaaccagtag accttttcat aaggttcgct tgatgtacca
      421 agatgaagct ggtttcggta gaatcagtaa actgggatct tgttggcctc caataggagt
      481 aggtccacat gtccatagtc actatatacg agaatttcgc tattgttatg gagctgttga
      541 tgcccataca ggcgaatcat ttttcttaat agctggtaga tgtaatactg agtggatgaa
      601 cgccttttta gaagagcttt cacaagctta tccagatgat
//
LOCUS       DAVDFK010000086          612 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.86, whole genome shotgun sequence.
ACCESSION   DAVDFK010000086 DAVDFK010000000
VERSION     DAVDFK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.86"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..>612
                     /locus_tag="VUR04_001990"
     CDS             <1..>612
                     /locus_tag="VUR04_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET5341809.1"
                     /translation="AYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILLKRT
                     GMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVRLGL
                     GKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYIENN
                     KSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENY"
BASE COUNT          247 a           77 c          119 g          169 t
ORIGIN      
        1 gagcctattt ttataacaga gaagcggaaa gatttaactt cttaaaagta ccggagatat
       61 tagttgatag agaagaattt cggggcttat cagcagaagc aattatcctt tattccatac
      121 ttcttaaacg gacaggaatg tcatttaaga ataactggat agacaaggaa ggcagagtat
      181 ttatctattt tactgtcgaa gaaattatga aaagaagaaa tatctcaaag ccaactgcca
      241 taaaaacatt agatgagctt gatgtaaaaa aaggaatagg actgatcgaa agagtaaggc
      301 ttggacttgg taagccgaac atcatttatg ttaaagactt tatgagtata tttcaggtaa
      361 aagaaaatga cttacagaag tcaaaaaact taacttcaga agtaaaagat tttaacctca
      421 gaagtaaaga aaatgaactt caagaggtta agaaccttga ctctaactat atagagaata
      481 ataagagtaa gtatagtaag agagaatata gttttggtga aaacggactt ggaacatttc
      541 aaaatgtgtt tttagctgct gaagatatat cggatttaca aatcataatg aactcacagc
      601 ttgagaatta ca
//
LOCUS       DAVDFK010000087          584 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.87, whole genome shotgun sequence.
ACCESSION   DAVDFK010000087 DAVDFK010000000
VERSION     DAVDFK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.87"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VUR04_001991"
     tRNA            complement(74..147)
                     /locus_tag="VUR04_001991"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VUR04_001992"
     tRNA            complement(157..242)
                     /locus_tag="VUR04_001992"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VUR04_001993"
     tRNA            complement(250..321)
                     /locus_tag="VUR04_001993"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VUR04_001994"
     tRNA            complement(344..416)
                     /locus_tag="VUR04_001994"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VUR04_001995"
     tRNA            complement(435..516)
                     /locus_tag="VUR04_001995"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
BASE COUNT          150 a          173 c          123 g          138 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgag
//
LOCUS       DAVDFK010000088          499 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.88, whole genome shotgun sequence.
ACCESSION   DAVDFK010000088 DAVDFK010000000
VERSION     DAVDFK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.88"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            1..432
                     /locus_tag="VUR04_001996"
                     /pseudo
     CDS             1..432
                     /locus_tag="VUR04_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          157 a          106 c           83 g          153 t
ORIGIN      
        1 ttcaagtgct atcactgttc aaaaatgatg gtcgctgaaa cttctatcgt caagaaaaat
       61 caccaaattc ctcgtatcat caaccaaaag attgctcaaa agttaattga aaagatttct
      121 atgaccgata ttgctcatca actggccatt tcaacttcaa ctgtcattcg aaagctcaat
      181 gacttccact ttgagtgtaa ttttagaaat cttcctgaga ttatgtcttg ggacgaatat
      241 gcctttacaa aaggaaagat gagctttatt gcgcaagatt ttgaaaagct cgatatcatc
      301 actgttcttg aaggtagaac acaagctgtc atccgagatc actttcttaa atatgataga
      361 tccgtccgat gtcgcgtcaa aatcattact atggatatgt ttagccctta ctatgacttg
      421 gctaaacagc ttcgctttca aatttctagg ctcaggctga aacagtctcc cagactgttt
      481 cactcccgaa tgcaaaaat
//
LOCUS       DAVDFK010000089          434 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.89, whole genome shotgun sequence.
ACCESSION   DAVDFK010000089 DAVDFK010000000
VERSION     DAVDFK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.89"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..>434
                     /locus_tag="VUR04_001997"
     CDS             <1..>434
                     /locus_tag="VUR04_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET5341810.1"
                     /translation="SPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGTQTYS
                     ATVNVYGNKDGKPDLDNIVATKKVTININGLISKETVQKAVADNVKDSIDVPAAYLEK
                     AKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNG"
BASE COUNT          150 a           97 c           92 g           95 t
ORIGIN      
        1 tctccactag gtgaaaacgt gaagaccaaa ggtcaatact tctatcaagt agccttggac
       61 ggaaatgtag ctggcaaaga aaaacaagcg ctcattgacc agttccgagc aaatggtact
      121 caaacttaca gcgctacagt caatgtctat ggtaacaaag acggtaaacc agacttggac
      181 aacatcgtag caactaaaaa agtcactatt aacataaacg gtttaatttc taaagaaaca
      241 gttcaaaaag ccgttgcaga caacgttaaa gacagtatcg atgttccagc agcctaccta
      301 gaaaaagcca agggtgaagg tccattcaca gcaggtgtca accatgtgat tccatacgaa
      361 ctcttcgcag gtgatggcat gttgactcgt ctcttgctca aggcatctga caaggcacca
      421 tggtcagata acgg
//
LOCUS       DAVDFK010000090          344 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.90, whole genome shotgun sequence.
ACCESSION   DAVDFK010000090 DAVDFK010000000
VERSION     DAVDFK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.90"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(169..>344)
                     /locus_tag="VUR04_001998"
     CDS             complement(169..>344)
                     /locus_tag="VUR04_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET5341811.1"
                     /translation="WVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTV
                     DSYRVNANGEWVN"
BASE COUNT          102 a           67 c           59 g          116 t
ORIGIN      
        1 aaaaaactcc gtagtctcta gcgctataaa tccggctaga gattacagag ttatttttta
       61 atctaaactt cctacaaggg tatattatct actgaaagga tatggtattt gtagggaata
      121 ctttaaagag ttcttacagg aagtcagtat taactagtta tattaggttt agtttaccca
      181 ttcaccattg gcattgactc tatagctatc tacagttgtg ttgactgcaa gggcacctaa
      241 gccattgaca tagtaccatt tatctgatac tttgaaccat tggcttgctt tcatagcacc
      301 tgatgcttca agatagtacc aggtatctcc atctttcacc caat
//
LOCUS       DAVDFK010000091          310 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.91, whole genome shotgun sequence.
ACCESSION   DAVDFK010000091 DAVDFK010000000
VERSION     DAVDFK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.91"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            complement(<1..>310)
                     /locus_tag="VUR04_001999"
     CDS             complement(<1..>310)
                     /locus_tag="VUR04_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5341812.1"
                     /translation="KGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVK
                     IITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKA
                     I"
BASE COUNT          103 a           57 c           60 g           90 t
ORIGIN      
        1 gatagccttg tattcatgag attttcgttc aaactgattc ataatttgaa cacgaaaacg
       61 actcatggca cggctgagat gttggataat atggaaacga tctagaacga ttttagcaca
      121 cggaaaaagc tgtttagcca agtcatagta aggactaaac atatccatcg taatgatttt
      181 cacttgacaa cgaacggctc tatcgtagcg aagaaagtga tttcggatga cagcttgtgt
      241 tctgccttca agaacagtga taatattaag attatcaaaa tcttgcgcaa tgaaactcat
      301 ctttccctta
//
LOCUS       DAVDFK010000092          273 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain S1301040306
            SAMEA3145635-rid19729303.denovo.92, whole genome shotgun sequence.
ACCESSION   DAVDFK010000092 DAVDFK010000000
VERSION     DAVDFK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145635
            Sequence Read Archive: ERR755435
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930110.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930110.1
            Genome Coverage       :: 291x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 10:12:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,000
            CDSs (total)                      :: 1,955
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 73 of 125
            Pseudo Genes (incomplete)         :: 46 of 125
            Pseudo Genes (internal stop)      :: 41 of 125
            Pseudo Genes (multiple problems)  :: 31 of 125
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145635-rid19729303.denovo.92"
                     /strain="S1301040306"
                     /db_xref="taxon:1313"
     gene            <1..>273
                     /locus_tag="VUR04_002000"
     CDS             <1..>273
                     /locus_tag="VUR04_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5341813.1"
                     /translation="QRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          124 a           36 c           46 g           67 t
ORIGIN      
        1 aacaacgaat agtagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aag
//
